Plasmapheresis machine

Abstract

The embodiment of the application belongs to the technical field of medical apparatuses, and particularly relates to a plasma separation machine. The embodiment of the application aims to solve the problem that the plasma separated by the related plasma separation machine is prone to denaturation. The plasma separation machine comprises a box body, a centrifugal machine, a plasma output assembly and a cooling device, the centrifugal machine, the plasma output assembly and the cooling device are all arranged in the box body, the plasma output assembly comprises a plasma tube and a plasma bag, the centrifugal machine has a liquid inlet end and a liquid outlet end, the liquid inlet end is configured to receive blood from a human body, the liquid outlet end is communicated with the plasma bag through the plasma tube, and the cooling device is configured to cool the plasma in at least one of the plasma bag and the plasma tube. Through the above arrangement, the cooling device cools the plasma in the plasma bag and / or the plasma tube, so as to reduce the temperature of the plasma in the plasma tube and the plasma bag, thereby preventing the plasma protein from denaturation and the coagulation factor from losing activity, and improving the quality of the plasma in the plasma bag.

Description

Technical Field

[0001] This application belongs to the field of medical device technology, specifically relating to a plasma separator. Background Technology

[0002] A plasma separator can separate plasma from blood and deliver the separated plasma into plasma bags for use by medical personnel.

[0003] In related technologies, a plasma separator includes a blood pump, a centrifuge, and a plasma bag. The blood pump is used to draw blood from the human body and deliver the blood to the centrifuge. The centrifuge separates the plasma from the blood and delivers the separated plasma to the plasma bag for use by medical personnel.

[0004] However, because the plasma separated by centrifuge is at a high temperature, prolonged exposure of the plasma to room temperature can easily lead to denaturation of plasma proteins and loss of activity of unstable coagulation factors, thus affecting the quality of the collected plasma. Summary of the Invention

[0005] The main objective of this application is to provide a plasma separator to solve the problem that the plasma separated by related plasma separators is prone to denaturation.

[0006] To achieve the above objectives, this application provides a plasma separator, including a housing, a centrifuge, a plasma output assembly, and a cooling device. The centrifuge, the plasma output assembly, and the cooling device are all disposed within the housing. The plasma output assembly includes a plasma tube and a plasma bag. The centrifuge has an inlet end and an outlet end. The inlet end is configured to receive blood from a human body, and the outlet end is connected to the plasma bag via the plasma tube. The cooling device is configured to cool the plasma in at least one of the plasma bag and the plasma tube.

[0007] In the preferred embodiment of the plasma separator described above, the cooling device includes a semiconductor cooling chip, which has a cold end and a hot end. A cold end heat sink is attached to the cold end, and the plasma tube is disposed on the side of the cold end heat sink away from the semiconductor cooling chip.

[0008] In the preferred embodiment of the plasma separator described above, a snap-fit ​​channel is provided on the side of the cold end heat sink away from the semiconductor cooling chip, and the plasma tube is snapped into the snap-fit ​​channel.

[0009] In the preferred embodiment of the above-mentioned plasma separator, the snap-fit ​​channel extends in a straight line, and the cross-section of the snap-fit ​​channel includes a fitting section, a first limiting section, and a second limiting section. The fitting section is arc-shaped. The first limiting section and the second limiting section are both straight sections. The first limiting section and the second limiting section are located at opposite ends of the fitting section in the circumferential direction. There is a preset gap between the end of the first limiting section away from the fitting section and the end of the second limiting section away from the fitting section.

[0010] In the preferred embodiment of the plasma separator described above, the bonding section is semi-circular, and both the first limiting section and the second limiting section are tangent to the bonding section.

[0011] In the preferred embodiment of the plasma separator described above, there are multiple locking channels, and the multiple locking channels are arranged in parallel.

[0012] In the preferred embodiment of the plasma separator described above, the plasma output assembly further includes a hook weigher and a plasma valve, with the plasma bag attached to the hook weigher; the plasma valve is located on the plasma tube and is configured to regulate the flow rate of plasma within the plasma tube.

[0013] In the preferred embodiment of the plasma separator described above, the plasma separator further includes a blood input component, which includes a blood tube, a blood valve, and a blood pump. The blood tube is connected to the inlet end of the centrifuge, the blood valve is disposed on the blood tube, and the blood valve is configured to regulate the flow rate of blood in the blood tube. The blood pump is disposed between the blood valve and the centrifuge.

[0014] In the preferred embodiment of the plasma separator described above, the blood input component further includes a first air detector, a second air detector, and a blood pressure monitor. The first air detector, the second air detector, and the blood pressure monitor are all disposed on the blood tube. The first air detector is disposed at the end of the blood valve away from the centrifuge. The blood pressure monitor is disposed between the first air detector and the blood valve. The second air detector is disposed between the blood valve and the blood pump.

[0015] In the preferred embodiment of the plasma separator described above, the plasma separator further includes an anticoagulant input component, which includes an anticoagulant container, an anticoagulant tube, an anticoagulant pump, and a third air detector. The anticoagulant container has an outlet, one end of the anticoagulant tube is connected to the outlet, and the other end of the anticoagulant tube is connected to the blood tube. The anticoagulant pump and the third air detector are both located on the anticoagulant tube.

[0016] Those skilled in the art will understand that the plasma separator of this application embodiment includes a housing, a centrifuge, a plasma output assembly, and a cooling device. The centrifuge, plasma output assembly, and cooling device are all housed within the housing. The plasma output assembly includes a plasma tube and a plasma bag. The centrifuge has an inlet end and an outlet end. The inlet end is configured to receive blood from the human body, and the outlet end is connected to the plasma bag via the plasma tube. The cooling device is configured to cool the plasma in at least one of the plasma bag and plasma tube. Through the above configuration, the cooling device cools the plasma in the plasma bag and / or plasma tube, thereby lowering the temperature of the plasma in the plasma tube and plasma bag, thus preventing plasma proteins from denaturing and coagulation factors from losing activity, thereby improving the quality of the plasma in the plasma bag. Attached Figure Description

[0017] A preferred embodiment of the plasma separator according to the present application will now be described with reference to the accompanying drawings. The drawings are as follows:

[0018] Figure 1 This is a schematic diagram of the structure of a plasma separator according to an embodiment of this application;

[0019] Figure 2 This is a front view of the plasma separator according to an embodiment of this application;

[0020] Figure 3 This is a top view of the plasma separator according to an embodiment of this application;

[0021] Figure 4 This is a schematic diagram of the structure of the semiconductor cooling chip, cold end heat sink, and hot end heat sink in the plasma separator of this application embodiment;

[0022] Figure 5 This is a schematic diagram of the cold end heat dissipation plate and the hot end heat dissipation plate in the plasma separator of this application embodiment.

[0023] In the attached image:

[0024] 10. Box body;

[0025] 20. Centrifuge;

[0026] 310. Plasma bag; 320. Hook weigher; 330. Plasma valve; 340. Fourth air detector;

[0027] 410. Semiconductor cooling chip;

[0028] 420. Cold end heat sink; 421. Snap-fit ​​channel; 422. Fitting section; 423. First limiting section; 424. Second limiting section;

[0029] 430. Hot-end heat sink;

[0030] 510. Blood valve; 520. Blood pump; 530. First air detector; 540. Second air detector; 550. Blood pressure monitor;

[0031] 610. Anticoagulant pump; 620. Third air detector;

[0032] 710. Saline bag; 720. Saline valve;

[0033] 800. Control Panel. Detailed Implementation

[0034] First, those skilled in the art should understand that these embodiments are merely used to explain the technical principles of the embodiments of this application and are not intended to limit the scope of protection of the embodiments of this application. Those skilled in the art can make adjustments as needed to adapt to specific application scenarios.

[0035] Secondly, it should be noted that in the description of the embodiments of this application, the terms "inner" and "outer" and other terms indicating the direction or positional relationship are based on the direction or positional relationship shown in the drawings. This is only for the convenience of description and is not intended to indicate or imply that the device or component must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation on the embodiments of this application.

[0036] Furthermore, it should be noted that, in the description of the embodiments of this application, unless otherwise explicitly specified and limited, the terms "connected" and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in the embodiments of this application according to the specific circumstances.

[0037] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0038] Medical staff often use plasma separators to separate plasma from human blood and transfer the plasma into plasma bags for use by medical staff.

[0039] The plasma separator in the relevant technology includes a blood pump, a centrifuge, and a plasma bag. The blood pump is used to draw blood from the human body and deliver the blood to the centrifuge. The centrifuge operates at high speed and separates the plasma from the blood. The separated plasma is delivered to the plasma bag for use by medical personnel.

[0040] Because the plasma separated by the centrifuge at high speed is at a high temperature, and the process of separating plasma from human blood is relatively long, the plasma is exposed to room temperature for a long time. The high temperature can easily cause the collected plasma proteins to denature and unstable clotting factors to lose their activity, thus affecting the quality of the collected plasma.

[0041] This embodiment provides a plasma separator that uses a cooling device to cool the plasma in plasma bags and / or plasma tubes, thereby reducing the temperature of the plasma in the plasma bags and plasma tubes, making it less likely for plasma proteins to denature and for coagulation factors to lose activity, thus improving the quality of the plasma in the plasma bags.

[0042] The principles and features of the embodiments of this application are described below with reference to the accompanying drawings. The examples given are only used to explain the embodiments of this application and are not intended to limit the scope of the embodiments of this application.

[0043] refer to Figure 1-3 The plasma separator provided in this application includes a housing 10, a centrifuge 20, a plasma output component, and a cooling device. The centrifuge 20 and the plasma output component are both disposed in the housing 10. The plasma output component includes a plasma tube (not shown in the figure) and a plasma bag 310. The centrifuge 20 has an inlet end and an outlet end. The inlet end is configured to receive blood from the human body. The centrifuge 20 rotates at high speed and separates the plasma from the blood. The plasma is discharged from the outlet end.

[0044] One end of the plasma tube is connected to the outlet end, and the other end of the plasma tube is connected to the plasma bag 310. The plasma tube transfers the plasma from the outlet end to the plasma bag 310.

[0045] The cooling device is configured to cool the plasma in at least one of the plasma bag 310 and the plasma tube, so as to lower the temperature of the plasma in the plasma bag 310, thereby making it less likely for plasma proteins to denature and for coagulation factors to lose activity, thus improving the quality of the plasma in the plasma bag 310.

[0046] The plasma separator in this embodiment includes a housing 10, a centrifuge 20, a plasma output assembly, and a cooling device. The centrifuge 20, plasma output assembly, and cooling device are all housed in the housing 10. The plasma output assembly includes a plasma tube and a plasma bag 310. The centrifuge 20 has an inlet end and an outlet end. The inlet end is configured to receive blood from the human body, and the outlet end is connected to the plasma bag 310 via the plasma tube. The cooling device is configured to cool the plasma in at least one of the plasma bag 310 and the plasma tube. Through the above configuration, the cooling device cools the plasma in the plasma bag 310 and / or the plasma tube, thereby lowering the temperature of the plasma in the plasma tube and plasma bag 310, making it less prone to plasma protein denaturation and coagulation factor inactivation, thus improving the quality of the plasma in the plasma bag 310.

[0047] refer to Figure 4 In some embodiments, the cooling device includes a semiconductor cooling chip 410, which utilizes the Peltier effect of semiconductor materials. When direct current passes through a thermocouple composed of two different semiconductor materials connected in series, heat can be absorbed and released at the two ends of the thermocouple, respectively. The end that absorbs heat is the cold end, and the end that releases heat is the hot end. The cold end can achieve the purpose of cooling.

[0048] Both the cold end and the hot end can be planar, with the cold end located on one side of the thermoelectric cooler 410 and the hot end on the other side. The cold end can be attached to a cold end heat sink 420. The plasma tube is positioned on the side of the cold end heat sink 420 furthest from the thermoelectric cooler 410. The cold end absorbs heat from the cold end heat sink 420, lowering its temperature. Since the plasma tube is positioned on the side of the cold end heat sink 420 furthest from the thermoelectric cooler 410, the cold end heat sink 420 cools the plasma tube and the plasma within it, thus lowering their temperature.

[0049] The semiconductor cooling chip 410 is small in size, which reduces the space occupied by the plasma separator; secondly, the semiconductor cooling chip 410 has no moving parts, and its reliability is also relatively high.

[0050] The hot end can be attached to a hot end heat sink 430, which can increase the heat exchange area between the hot end and the air to improve the heat dissipation efficiency of the hot end.

[0051] The housing 10 may have mounting holes, and the semiconductor cooling chip 410, the cold end heat sink 420 and the hot end heat sink 430 are integrally installed in the mounting holes. The cold end heat sink 420 may be located outside the housing 10, and the semiconductor cooling chip 410 and the hot end heat sink 430 may both be located inside the housing 10.

[0052] Furthermore, a fan can also be installed inside the housing 10, with the fan positioned close to the heat dissipation plate 430 at the hot end to accelerate the heat exchange efficiency between the heat dissipation plate 430 at the hot end and the air inside the housing 10, thereby improving the heat dissipation efficiency at the hot end.

[0053] Continue to refer to Figure 4 and Figure 5 In some implementations, a snap-fit ​​channel 421 may be provided on the side of the cold end heat sink 420 away from the semiconductor cooling chip 410, and the plasma tube is snapped into the snap-fit ​​channel 421.

[0054] Specifically, the snap-fit ​​channel 421 can extend in a straight line. The cross-section of the snap-fit ​​channel 421 may include a fitting section 422, a first limiting section 423, and a second limiting section 424. The fitting section 422 is arc-shaped. The first limiting section 423 and the second limiting section 424 are both straight segments. The first limiting section 423 and the second limiting section 424 are located at opposite ends of the fitting section 422 in the circumferential direction. There is a preset gap between the end of the first limiting section 423 away from the fitting section 422 and the end of the second limiting section 424 away from the fitting section 422. The fitting section 422, the first limiting section 423, and the second limiting section 424 surround the snap-fit ​​channel 421. The plasma tube passes through the preset gap and is inserted into the snap-fit ​​channel 421.

[0055] The plasma tube is a cylindrical hollow tube. After the plasma tube passes through the snap-fit ​​channel 421, part of the outer side of the plasma tube is attached to the fitting section 422. The first limiting section 423 and the second limiting section 424 are used to restrict the radial degree of freedom of the plasma tube, so that the plasma tube is not easy to slide out of the snap-fit ​​channel 421, and the snap-fit ​​channel 421 fixes the plasma tube more securely.

[0056] Furthermore, the fitting section 422 can be semi-circular, and the first limiting section 423 and the second limiting section 424 can both be tangent to the fitting section 422, that is, the first limiting section 423 and the second limiting section 424 are parallel, so that the plasma tube can more easily slide into or out of the locking channel 421 through the gap between the first limiting section 423 and the second limiting section 424, making it convenient for medical staff to lock the plasma tube into or out of the locking channel 421.

[0057] Of course, the straight lines containing the first limiting segment 423 and the second limiting segment 424 can also have an angle, and the gap between the first limiting segment 423 and the second limiting segment 424 gradually decreases in the direction away from the fitting segment 422, so that the plasma tube is not easy to slip out from the gap between the first limiting segment 423 and the second limiting segment 424 after it is inserted into the locking channel 421.

[0058] Multiple snap-fit ​​channels 421 can be provided on the side of the cold end heat sink 420 away from the semiconductor cooling chip 410. The multiple snap-fit ​​channels 421 can be arranged in parallel so that medical staff can more conveniently and quickly snap the plasma tube into the snap-fit ​​channel 421.

[0059] In addition to extending in a straight line, the snap-fit ​​channel 421 can also extend in a curve. For example, the snap-fit ​​channel 421 can extend in a spiral shape to reduce the space occupied by the snap-fit ​​channel 421.

[0060] In some other possible implementations, the plasma tube can be attached to the cold end heat sink 420 with adhesive tape. When it is necessary to remove the plasma tube from the cold end heat sink 420, simply peel off the adhesive tape, which is convenient and quick.

[0061] Continue to refer to Figure 1 The aforementioned cold end heat dissipation plate 420 can be set on the outside of the box 10, and the plasma bag 310 can also be set on the outside of the box 10. The plasma bag 310 is set close to the cold end heat dissipation plate 420 so that the cold end heat dissipation plate 420 can cool the plasma in the plasma tube and the plasma in the plasma bag 310, so that the temperature of the plasma in the plasma bag 310 is lower, thereby further preventing the denaturation of plasma proteins and the loss of activity of coagulation factors, and improving the quality of the plasma in the plasma bag 310.

[0062] In other embodiments, the cooling device may include a compressor, a condenser, a throttling element, and an evaporator, which are connected in series in sequence via pipelines through which refrigerant flows, and the plasma bag 310 and part of the plasma tube are located near the evaporator.

[0063] The compressor compresses the low-temperature, low-pressure gaseous refrigerant into a high-temperature, high-pressure gaseous refrigerant. The high-temperature, high-pressure gaseous refrigerant is then transported to the condenser, where it dissipates heat and becomes a normal-temperature, high-pressure liquid refrigerant. As the normal-temperature, high-pressure liquid refrigerant flows through the throttling element, it cools and depressurizes, becoming a low-temperature, low-pressure liquid refrigerant. When the low-temperature, low-pressure liquid refrigerant flows through the evaporator, it exchanges heat with the plasma tube, absorbing heat from the plasma tube and the plasma inside. After absorbing heat, it vaporizes into a low-temperature, low-pressure gaseous refrigerant. This vaporization absorbs a large amount of heat, thus lowering the temperature of the plasma bag 310 and the plasma inside the plasma tube.

[0064] In some possible embodiments, the cooling device may further include a cooling box disposed on the outside of the housing 10 and covering the outside of the plasma bag 310.

[0065] In the implementation of the cooling device including the semiconductor cooling chip 410, the cold end of the semiconductor cooling chip 410 or the cold end heat dissipation plate 420 is disposed in the cooling box to reduce the temperature inside the cooling box, thereby reducing the temperature of the plasma bag 310 and the plasma inside the plasma bag 310.

[0066] In the implementation of the cooling device, which includes a compressor, a condenser, a throttling element, and an evaporator, the evaporator can be installed inside the cooling box. The evaporator can absorb heat from the cooling box, thereby lowering the temperature inside the cooling box and consequently lowering the temperature of the plasma bag 310 and the plasma inside the plasma bag 310.

[0067] Continue to refer to Figure 1 In some embodiments, the plasma output assembly may further include a hook weigher 320 and a plasma valve 330, with the plasma bag 310 attached to the hook weigher 320, which weighs the plasma bag 310 to obtain a target weight of plasma; the plasma valve 330 is disposed on the plasma tube and is configured to regulate the flow rate of plasma in the plasma tube.

[0068] The weighing device 320 on the hook can be manually observed, and when the weight of the plasma bag 310 reaches the target weight, the plasma valve 330 can be manually adjusted to prevent plasma from flowing into the plasma bag 310.

[0069] Furthermore, the plasma separator may also include a main controller, and the hook weigher 320 and the plasma valve 330 may both be electrically connected to the main controller. The main controller may be configured to close the plasma valve 330 when the weight of the plasma weighed by the hook weigher 320 reaches the target weight.

[0070] The plasma output assembly may also include a fourth air detector 340, which is disposed on the plasma tube between the centrifuge 20 and the plasma valve 330 to detect the air content in the plasma discharged from the centrifuge 20.

[0071] In some embodiments, the plasma separator may further include a blood input assembly, which includes a blood tube, a blood valve 510, and a blood pump 520. The blood tube is connected to the inlet end of the centrifuge 20, the blood valve 510 is disposed on the blood tube and configured to regulate the flow rate of blood in the blood tube, and the blood pump 520 is disposed between the blood valve 510 and the centrifuge 20.

[0072] The end of the blood tube away from the centrifuge 20 can be connected to a blood vessel in the human body through a disposable injection needle. The blood pump 520 allows blood from the human body to be continuously pumped into the centrifuge 20. The blood valve 510 is used to regulate the flow rate of blood in the blood tube. When blood needs to be drawn from the human body, the blood valve 510 is opened, and when blood does not need to be drawn from the human body, the blood valve 510 is closed.

[0073] In some embodiments, the blood input component may further include a first air detector 530, a second air detector 540, and a blood pressure monitor 550, all of which are disposed in the blood tube. The first air detector 530 is disposed at the end of the blood valve 510 away from the centrifuge 20 to detect the air content in the blood in the blood tube at the front end of the blood valve 510.

[0074] The blood pressure monitor 550 is located between the first air detector 530 and the blood valve 510. The blood pressure monitor 550 has an exhaust manifold through which air in the blood flowing through the blood pressure monitor 550 can be expelled.

[0075] A second air detector 540 is disposed between the blood valve 510 and the blood pump 520 to detect the air content in the blood in the blood tube located between the blood valve 510 and the blood pump 520.

[0076] Furthermore, multiple first air detectors 530 can be configured, with multiple first air detectors 530 connected in series in the blood tube, so that the air content in the blood tube detected by the first air detectors 530 is more accurate.

[0077] In some embodiments, the plasma separator may further include an anticoagulant input assembly, which includes an anticoagulant container, an anticoagulant tube, an anticoagulant pump 610, and a third air detector 620. The anticoagulant container is used to contain anticoagulant and has an outlet. One end of the anticoagulant tube is connected to the outlet, and the other end of the anticoagulant tube is connected to a blood tube to deliver anticoagulant from the anticoagulant container to the blood tube. The anticoagulant can prevent blood from clotting.

[0078] Both the anticoagulant pump 610 and the third air detector 620 are located in the anticoagulant tubing. The anticoagulant pump 610 allows for the continuous delivery of anticoagulant from the anticoagulant container to the blood tubing. The third air detector 620 can detect the air content within the anticoagulant tubing.

[0079] Furthermore, the anticoagulant tube can be connected to the blood tube located at the front end of the first air detector 530, or the anticoagulant tube can be connected to the end of the blood tube away from the centrifuge 20, so that the blood from the human body can be quickly mixed with the anticoagulant after flowing into the blood tube, thereby effectively preventing the blood in the blood tube from clotting.

[0080] The anticoagulant inlet assembly may also include an electronic scale configured to measure the weight of the anticoagulant flowing from the anticoagulant container to the anticoagulant tube, so as to balance the amount of anticoagulant flowing into the blood tube with the amount of blood in the blood tube. This can avoid both excessive anticoagulant flowing into the blood tube, which would lead to waste, and insufficient anticoagulant flowing into the blood tube, which would lead to blood clotting.

[0081] In some embodiments, the plasma separator may further include a saline inlet assembly, which may include a saline bag 710, a saline tube, and a saline valve 720. The saline tube is connected between the saline bag 710 and the plasma tube to deliver the saline in the saline bag 710 to the plasma tube.

[0082] The plasma separator can include a blood drawing process and a blood transfusion process. During the blood drawing process, the blood flow direction is: human body, blood tube, centrifuge 20, plasma tube, plasma bag 310.

[0083] During blood transfusion, the blood flows in the following direction: plasma tube, centrifuge 20, blood tube, and then the human body. After the plasma is collected into the plasma bag 310, the whole blood (with plasma separated) in the centrifuge 20 is mixed with physiological saline before being transported into the human body.

[0084] Obtaining the target weight of plasma requires multiple blood draws and transfusions to avoid damaging the body by drawing too much blood at once.

[0085] The plasma separator may also include a control panel 800, through which the speed of the centrifuge 20 and the target weight of the plasma are set.

[0086] In summary, the plasma separator of this application embodiment includes a housing 10, a centrifuge 20, a plasma output assembly, and a cooling device. The centrifuge 20, plasma output assembly, and cooling device are all housed in the housing 10. The plasma output assembly includes a plasma tube and a plasma bag 310. The centrifuge 20 has an inlet end and an outlet end. The inlet end is configured to receive blood from the human body, and the outlet end is connected to the plasma bag 310 via the plasma tube. The cooling device is configured to cool the plasma in at least one of the plasma bag 310 and the plasma tube. Through the above configuration, the cooling device cools the plasma in the plasma bag 310 and / or the plasma tube, thereby reducing the temperature of the plasma in the plasma tube and plasma bag 310, making it less prone to plasma protein denaturation and coagulation factor inactivation, thus improving the quality of the plasma in the plasma bag 310.

[0087] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A plasma separation machine characterized by, The blood plasma separation machine comprises a box body, a centrifuge, a blood plasma output assembly and a cooling device, the centrifuge, the blood plasma output assembly and the cooling device are arranged in the box body, the blood plasma output assembly comprises a blood plasma tube and a blood plasma bag, the centrifuge has a liquid inlet end and a liquid outlet end, the liquid inlet end is configured to receive blood from a human body, the liquid outlet end is communicated with the blood plasma bag through the blood plasma tube; the cooling device is configured to cool the blood plasma in the blood plasma bag and the blood plasma tube; the cooling device comprises a semiconductor refrigeration sheet, the semiconductor refrigeration sheet has a cold end and a hot end, the cold end is attached with a cold end heat sink, the hot end is attached with a hot end heat sink, the blood plasma tube is arranged on a side of the cold end heat sink away from the semiconductor refrigeration sheet; the cold end heat sink is arranged on the outside of the box body, the blood plasma bag is arranged on the outside of the box body, and the blood plasma bag is arranged close to the cold end heat sink, so that the cold end heat sink cools the blood plasma in the blood plasma tube and the blood plasma bag; the box body is provided with a mounting hole, the semiconductor refrigeration sheet, the cold end heat sink and the hot end heat sink are arranged in the mounting hole, and the semiconductor refrigeration sheet and the hot end heat sink are arranged in the box body; the blood plasma output assembly further comprises a hook scale and a blood plasma valve, and the blood plasma bag is hung on the hook scale.

2. The plasma separator according to claim 1, characterized in that a clamping channel is arranged on a side of the cold end heat sink away from the semiconductor refrigeration sheet, and the blood plasma tube is clamped in the clamping channel.

3. The plasma separator according to claim 2, characterized in that the clamping channel extends in a straight line, the cross section of the clamping channel comprises a fitting section, a first limiting section and a second limiting section, and the fitting section is arc-shaped; the first limiting section and the second limiting section are both straight sections, the first limiting section and the second limiting section are arranged at opposite ends of the circumferential direction of the fitting section, and a preset gap is formed between an end of the first limiting section away from the fitting section and an end of the second limiting section away from the fitting section.

4. The plasmafilter according to claim 3, characterized in that the fitting section is semicircular, and the first limiting section and the second limiting section are tangent to the fitting section.

5. The plasma separator according to claim 3, characterized in that a plurality of clamping channels are arranged in parallel.

6. The blood plasma separation machine according to any one of claims 1 to 5, wherein the blood plasma valve is arranged in the blood plasma tube, and the blood plasma valve is configured to adjust the flow of the blood plasma in the blood plasma tube.

7. The plasma separator according to any one of claims 1 to 5, characterized in that the blood plasma separation machine further comprises a blood input assembly, the blood input assembly comprises a blood tube, a blood valve and a blood pump, the blood tube is connected to the liquid inlet end of the centrifuge, the blood valve is arranged in the blood tube, the blood valve is configured to adjust the flow of the blood in the blood tube, and the blood pump is arranged between the blood valve and the centrifuge.

8. The plasmafilter according to claim 7, characterized in that The blood input assembly further comprises a first air detector, a second air detector and a blood pressure detector, the first air detector, the second air detector and the blood pressure detector are arranged in the blood tube, the first air detector is arranged at an end of the blood valve away from the centrifugal machine, the blood pressure detector is arranged between the first air detector and the blood valve, and the second air detector is arranged between the blood valve and the blood pump.

9. The plasmafilter as claimed in claim 7, characterized in that The plasma separator further comprises an anticoagulant input assembly, the anticoagulant input assembly comprises an anticoagulant container, an anticoagulant tube, an anticoagulant pump and a third air detector, the anticoagulant container has a liquid outlet, one end of the anticoagulant tube is connected with the liquid outlet, the other end of the anticoagulant tube is communicated with the blood tube, and the anticoagulant pump and the third air detector are arranged in the anticoagulant tube.

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