A urine separation and recovery system for preparing urokinase

Abstract

The application provides a urine separation and recovery system for preparing urokinase, which comprises a separation device, the separation device comprises a separation mechanism and a detection mechanism, the separation mechanism comprises a plurality of separation test tubes, the separation test tubes comprise two groups of piston pieces, the two groups of piston pieces are used for separating the urine in the separation test tubes into three layers of upper, middle and lower, the middle layer of the separation test tubes is sleeved with a heating piece, and the detection mechanism comprises a first detection piece, a second detection piece and a third detection piece; the separation device is further provided with a control box, the control box comprises a urine sample database, a collection module and an analysis module for acquiring actual information of urine sugar, actual information of heavy metal and actual information of bacteria, and an analysis module for issuing abnormal instructions and normal instructions; the application has the advantages that the urine in each urine collecting cylinder can be accurately analyzed, so that the urine in the urine storage cylinder is healthy urine.

Description

Technical Field

[0001] This invention relates to the field of urine detection, and more specifically to a urine separation and recovery system for preparing urokinase. Background Technology

[0002] Urokinase is used in the endogenous fibrinolytic system. It catalyzes the cleavage of plasminogen into plasmin, which can not only degrade fibrin clots but also degrade fibrinogen, coagulation factor V, and coagulation factor VIII in the blood circulation, thereby exerting a thrombolytic effect. Urokinase is mainly isolated from human urine or cultured from human kidney tissue. This application is aimed at the former method. Currently, the urine used for the extraction and research of urokinase is mainly collected from students in schools. Although most of the urine in the student population is healthy and qualified, some urine contains unqualified urine.

[0003] High levels of heavy metals, bacteria, and glucose in urine can all affect the extraction of urokinase. Therefore, urine separation and collection in the early stages are essential for subsequent urokinase extraction. If healthy and unhealthy urine are mixed together for urokinase extraction, the extraction efficiency will be low. If each student's urine needs to be tested beforehand, it will cause some inconvenience for the students. Summary of the Invention

[0004] To address the shortcomings of existing technologies, the present invention aims to provide a urine separation and recovery system for preparing urokinase. This urine separation and recovery system can accurately analyze the urine in each urine collection cylinder to ensure that the urine in the storage cylinder is healthy urine.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] A urine separation and recovery system for preparing urokinase includes a separation device, which includes a separation mechanism and a detection mechanism. The separation mechanism includes several separation test tubes, each containing two sets of pistons. The test tubes are filled with urine, and the two sets of pistons are used to separate the urine in the test tubes into upper, middle, and lower layers. A heating element is fitted around the outer ring of the middle layer of the separation test tubes. The detection mechanism includes a first detection element, a second detection element, and a third detection element.

[0007] The separation device is also equipped with a control box, which includes a urine sample database. The urine sample database includes urine glucose reference information, heavy metal ion reference information, and bacterial reference information. The urine glucose reference information reflects the normal range of urine glucose content, the heavy metal ion reference information reflects the normal range of urine heavy metal content, and the bacterial reference information reflects the normal types and content range of bacteria in urine.

[0008] The control box also includes a data acquisition module and an analysis module;

[0009] The acquisition module obtains the content of urinary sugar in the upper layer of urine in the separation tube detected by the first detection device as the actual information of urinary sugar, obtains the content of heavy metal ions in the middle layer of urine in the separation tube detected by the second detection device as the actual information of heavy metals, and obtains the content of bacteria in the precipitated urine residue in the lower layer of urine in the separation tube detected by the third detection device as the actual information of bacteria.

[0010] The analysis module acquires the actual information collected by the acquisition module, and then acquires the reference information from the urine sample database. It compares the actual information with the reference information one by one. If any actual information does not match the corresponding reference information, an abnormal command is issued; otherwise, a normal command is issued.

[0011] Furthermore, the separation device includes an upper chamber, a middle chamber, and a lower chamber separated by a partition. The separation mechanism and the detection mechanism are both located in the middle chamber. The upper chamber is also equipped with a transfer mechanism that carries a urine collection tube. The lower chamber is equipped with a waste urine tube and several urine storage tubes. The top of the upper chamber is also equipped with an extraction mechanism that extracts urine from the urine collection tube into a separation test tube, a urine storage tube, or a waste urine tube. A water tank is also provided on one side of the upper chamber. The water tank is connected to the extraction mechanism, the separation test tube, the first detection mechanism, the second detection mechanism, and the third detection mechanism by a cleaning pipeline.

[0012] Furthermore, the separation mechanism also includes a test tube support, which is horizontally connected to the front and rear side walls of the central chamber. The test tube support has several insertion holes for fixing the separation test tubes. The separation test tube includes an upper part, a middle part, and a lower part. A first arc-shaped part is provided at the connection between the upper part and the middle part, and a second arc-shaped part is provided at the connection between the middle part and the lower part. The diameter of the upper part and the lower part are the same, and the diameter of the middle part is larger than the diameter of the upper part. The heating element is sleeved on the second arc-shaped part and the middle part. Two sets of pistons are located in the upper part and the lower part, respectively. Both sets of pistons include a piston head and a first power source. The diameter of the piston head is the same as the diameter of the upper part, and the first power source drives the piston head to move.

[0013] Furthermore, a heat insulation sheet is provided on the side of the piston head facing the middle portion, and a sealing structure that contacts the separation test tube is provided on the side of the piston head away from the middle portion.

[0014] Furthermore, the first detection component includes a detection box, a test strip box, and a first camera. The detection box is horizontally located on one side of the upper part of the separation tube. A flow channel is provided between the upper part and the detection box. A paper inlet is provided on the side of the detection box away from the separation tube. A drive roller assembly is also provided on the detection box outside the paper inlet. The upper surface of the detection box is transparent. The first camera is located above the detection box with its lens vertically facing the detection box. A sluice for draining or cleaning is provided at the bottom of the detection box. The test strip box is located on one side of the paper inlet. Several urine glucose test strips are vertically stacked inside the test strip box. A partial opening is provided on the side of the test strip box near the paper inlet. A paper-pulling device is also provided on the test strip box. The paper-pulling device adsorbs the test strips at the opening and rotates them to the drive roller assembly. The drive roller assembly is used to partially transport the test strips into the paper inlet.

[0015] Furthermore, the second detection element includes a reagent replenisher and a spectrometer. A first collection tube is provided between the spectrometer and the second arc-shaped part. The first collection tube is also provided with a replenishment tube communicating with the reagent replenisher. The heating element includes a heating cover. The heating cover is filled with circulating water. The heating cover is also provided with a temperature sensor for detecting the temperature of the circulating water.

[0016] Furthermore, the third testing component includes an electron microscope and a testing substrate. The testing substrate is located on the testing stage of the electron microscope. The testing substrate includes an upper substrate and a lower substrate. Baffles are provided on opposite sides of the lower substrate, and collection troughs for collecting wastewater are provided on opposite sides. A urine residue tube communicating with the bottom of the lower part of the separation test tube is provided at the edge of the lower substrate. A telescopic column passing through the lower substrate is provided at the bottom of the upper substrate. The telescopic column is used to drive the upper substrate to adhere to or move away from the lower substrate.

[0017] Furthermore, the detection mechanism also includes a fourth detection element, which includes a second camera located on opposite sides of the separation mechanism;

[0018] The urine sample database also includes urine reference color information, which reflects the RGB values ​​of healthy urine.

[0019] The acquisition module obtains the color of the urine in the separation tube captured by the second camera as the actual color information of the urine.

[0020] The analysis module acquires the actual urine color information from the acquisition module and the urine reference color information from the urine sample database. It compares the actual urine color information with the urine reference color information. If the difference between the two is large, an abnormal command is issued; if the difference is small, a normal command is issued.

[0021] Furthermore, the urine sample database also includes a scoring table and a control range. The scoring table contains the scoring values ​​of each reference information, and the control range reflects the normal score range of urine. The control box also includes a statistics module and a control module. The statistics module obtains the score corresponding to each actual information in the collection module, and then calculates the total score according to the weight formula.

[0022] The control module obtains the total score from the statistics module and compares the total score with the control score range. If the total score falls within the control score range, the control module extracts the urine from the urine collection cylinder and transports it to the urine storage cylinder. If the total score does not fall within the control score range, the control module extracts the urine from the urine collection cylinder and transports it to the waste urine cylinder.

[0023] Furthermore, the extraction mechanism includes an extraction frame and a plurality of extraction suction heads vertically connected to the extraction frame. One end of each extraction suction head is provided with a telescopic hose for conveying urine. The extraction frame is provided with a power unit for driving the extraction frame to move so that the extraction suction heads extend into or move out of the urine collection cylinder.

[0024] The beneficial effects of this invention are as follows: 1. By integrating the separation mechanism and the detection mechanism into the separation device, the user's urine can be accurately analyzed and separated into normal and healthy urine. Specifically, the device is equipped with separation test tubes that are thin at the top, coarse in the middle, and thin at the bottom. Two sets of pistons can separate the urine in the separation test tubes into three layers: top, middle, and bottom. Depending on the purpose of the detection, the temperature of the corresponding layer of urine can be adjusted or reagents can be added for subsequent detection. In addition, visual detection, urine sugar detection, heavy metal detection, and colony detection can be set up to accurately determine the health status of each user's urine, which is beneficial for subsequent urokinase culture.

[0025] 2. Through the coordinated arrangement of the paper feeding component and the drive roller assembly, the test strips in the test strip box can be continuously fed into the test box, so that the test strips are partially immersed in the urine in the test box. Then, the first camera above takes an image of the test strips in the test box for urine sugar content analysis. The drive roller assembly can transport the tested test strips out of the test box so that new test strips can be fed back into the test box. Its first detection component can work with the separation test tube and the internal piston component to realize urine sugar detection, which is faster and more hygienic than manual testing.

[0026] 3. By combining the detection substrate and the urine residue tube, the urine residue that has settled in the lower layer of the separation tube can be transported to the detection substrate for detection. After detection, it can be rinsed with clean water and the urine residue transportation and detection can be repeated. Specifically, the baffles on both sides of the detection substrate can prevent the urine residue from flowing out from both sides, and the collection tanks on both sides can collect the washing wastewater. Compared with a fixed detection substrate, the detection substrate in this invention can automatically cooperate with the input, pressing and rinsing of urine residue to automatically repeat the detection.

[0027] 4. The corresponding control system can detect specific components in each user's urine, automatically analyze and judge the results, and then control the corresponding structure to perform the action. The statistical module can also assign a score to the total of specific components in the urine, and determine the qualification level of the urine based on the score, so as to decide whether the urine is transported to the waste urine container or the urine storage container. Intelligent detection and separation of urine can improve the separation efficiency of urine and avoid human contact and contamination to a greater extent. Attached Figure Description

[0028] Figure 1 This is an overall structural diagram of the present invention;

[0029] Figure 2 This is a diagram of the control system in this invention;

[0030] Figure 3 This is a diagram showing the internal structure of the central chamber of the present invention;

[0031] Figure 4 This is a three-dimensional view of the separation test tube in this invention;

[0032] Figure 5 This is a cross-sectional view of the separation test tube in this invention;

[0033] Figure 6 This is a structural diagram of the detection substrate in this invention.

[0034] Reference numerals: 1. Separation mechanism; 2. Detection mechanism; 3. Separation test tube; 31. Upper part; 32. Middle part; 33. Lower part; 34. First arc-shaped part; 35. Second arc-shaped part; 4. Piston component; 41. Piston head; 42. First power source; 43. Heat insulation sheet; 5. Heating component; 6. First detection component; 61. Detection box; 62. Test paper box; 63. First camera; 64. Flow channel; 65. Paper inlet; 66. Drive roller group; 67. Paper feeding component; 7. Second detection component; 71. Reagent replenisher; 72. Spectrometer; 8. Third... 81. Electron microscope; 82. Detection substrate; 821. Upper substrate; 822. Lower substrate; 823. Baffle; 824. Collection tank; 9. Control box; 10. Transfer mechanism; 11. Urine collection tube; 12. Waste urine tube; 13. Urine storage tube; 14. Extraction mechanism; 141. Extraction rack; 142. Extraction pipette tip; 15. Water tank; 16. Test tube holder; 111. Upper chamber; 112. Middle chamber; 113. Lower chamber; 101. Acquisition module; 102. Analysis module; 103. Statistical module; 104. Control module. Detailed Implementation

[0035] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments. Identical components are denoted by the same reference numerals. It should be noted that the terms "front," "rear," "left," "right," "upper," and "lower" used in the following description refer to directions in the accompanying drawings, and the terms "bottom surface," "top surface," "inner," and "outer" refer to directions toward or away from the geometric center of a specific component, respectively.

[0036] Currently, the urine samples used for urokinase extraction and research are mainly collected from school students. Although most urine from students is healthy and meets standards, some samples contain unsuitable substances, such as high levels of heavy metals, bacteria, and glucose, which can affect urokinase extraction. Therefore, urine separation and collection are essential for subsequent urokinase extraction. Mixing healthy and unhealthy urine together for extraction would result in low efficiency. Furthermore, requiring urine testing for each student would be inconvenient. Therefore, this invention designs a device specifically for urine separation and processing, as follows: Figure 1As shown, the device includes a separation unit comprising an upper chamber 111, a middle chamber 112, and a lower chamber 113 separated by a partition. The separation unit includes a transfer mechanism 10, an extraction mechanism 14, and a water tank 15 located in the upper chamber 111; a separation mechanism 1 and a detection mechanism 2 located in the middle chamber 112; and a waste urine container 12 and several urine storage containers 13 located in the lower chamber 113. The transfer mechanism 10 is designed to transfer the urine collection container 11 containing urine provided by the user to below the extraction mechanism 14. Specifically, the transfer mechanism 10 may have a horizontally arranged slide rail within the upper chamber 111. The slide rail is equipped with a slide seat for carrying the urine collection cylinder 11, and the transfer is achieved by sliding. The transfer mechanism 10 can also be a conveyor belt horizontally arranged in the upper chamber 111, and the conveyor belt is equipped with a grid for separating each urine collection cylinder 11. The urine collection cylinder 11 is transferred by the conveyor belt. Secondly, the purpose of the extraction mechanism is to extract a certain amount of urine from the urine collection cylinder 11 and transport it to the separation mechanism 1 for separation and then testing. After the testing is completed, the extraction mechanism can also extract the urine from the urine collection cylinder 11 to the urine storage cylinder 13 or the waste urine cylinder 12 (specifically, the extraction mechanism 14 includes an extraction frame 141 and a vertically connected frame 141). The collection frame 141 has several suction heads 142, one end of which is equipped with a telescopic hose for conveying urine. The collection frame 141 is equipped with a power unit for driving the collection frame 141 to move so that the suction heads 142 can extend into or out of the urine collection cylinder 11. If the transfer mechanism 10 has 6 urine collection cylinders 11 arranged side by side, then the collection frame 141 has 6 suction heads 142 arranged side by side. The separation mechanism 1 includes several separation test tubes 3, each containing two sets of pistons 4. The separation test tubes 3 are filled with urine, and the two sets of pistons 4 are used to move the urine inside the separation test tubes 3. The urine is separated into three layers: upper, middle and lower. The middle layer of the separation tube 3 is fitted with a heating element 5. The detection mechanism 2 includes a first detection element 6, a second detection element 7 and a third detection element 8. The pipeline distribution includes: a pipeline between the extraction mechanism 14 and the separation tube 3, the urine storage cylinder 13 and the waste urine cylinder 12; a pipeline between the separation tube 3 and the second detection element 7 and the third detection element 8; a pipeline between the first detection element 6 and the waste urine cylinder 12; and a cleaning pipeline between the water tank 15 and the extraction mechanism 14, the separation tube 3, the first detection mechanism 2, the second detection mechanism 2 and the third detection mechanism 2.Its beneficial effects are as follows: By integrating the separation mechanism 1 and the detection mechanism 2 within the separation device, it can accurately analyze the user's urine and separate normal, healthy urine. Specifically, it is equipped with separation test tubes 3 that are thin at the top, coarse in the middle, and thin at the bottom. Two sets of pistons 4 separate the urine within the separation test tubes 3 into upper, middle, and lower layers. Depending on the purpose of the test, the temperature of the corresponding layer of urine can be adjusted or reagents can be added for subsequent testing. Combined with visual inspection, urine glucose detection, heavy metal detection, and colony detection, it can accurately determine the health status of each user's urine, which is beneficial for subsequent urokinase culture.

[0037] like Figure 2 As shown, the separation device is also equipped with a control box 9, which contains a urine sample database. The urine sample database includes urine glucose reference information, heavy metal ion reference information, and bacterial reference information. The urine glucose reference information reflects the normal range of urine glucose content (each urine glucose content range corresponds to a test strip color range), the heavy metal ion reference information reflects the normal range of urine heavy metal content, and the bacterial reference information reflects the normal types and content range of bacteria in urine.

[0038] The control box 9 also includes a data acquisition module 101 and an analysis module 102;

[0039] The acquisition module 101 acquires the content of urinary sugar in the upper layer of urine in the separation tube 3 as the actual information of urinary sugar by the first detection element 6, acquires the content of heavy metal ions in the middle layer of urine in the separation tube 3 as the actual information of heavy metals by the second detection element 7, and acquires the content of bacteria in the precipitated urine residue in the lower layer of urine in the separation tube 3 as the actual information of bacteria by the third detection element 8.

[0040] The analysis module 102 acquires the actual information collected by the acquisition module 101, and then acquires the reference information in the urine sample database. It compares the actual information with the reference information one by one. If any actual information does not match the corresponding reference information, an abnormal command is issued; otherwise, a normal command is issued.

[0041] For example, in the urine sample database, the reference information for urine glucose is A-A', and its corresponding color is S-S'; the reference information for heavy metals is B-B'; and the reference information for bacteria is C-C'. If the urine test result for person A is test strip color 's', the corresponding reference information for urine glucose is a-a', the actual information for heavy metals is b-b', and the actual information for bacteria is c-c', then the analysis module 102 compares a-a' with A-A', b-b' with B-B', and c-c' with C-C'. The result is that a-a' is not within A-A', while the rest fall within the range of the reference information. Therefore, it can be determined that person A's urine is unqualified, an abnormal command will be issued, and the extraction mechanism 14 will extract person A's urine collection cylinder 11 into the waste urine cylinder 12.

[0042] like Figure 4 and Figure 5 As shown, the separation mechanism 1 also includes a test tube support 16, which is horizontally connected to the front and rear side walls of the central chamber 112. The test tube support 16 has several insertion holes for fixing the separation test tubes 3. The separation test tube 3 includes an upper part 31, a middle part 32, and a lower part 33. A first arc-shaped portion 34 is provided at the connection between the upper part 31 and the middle part 32, and a second arc-shaped portion 35 is provided at the connection between the middle part 32 and the lower part 33. The diameters of the upper part 31 and the lower part 33 are the same, while the diameter of the middle part 32 is larger than the diameter of the upper part 31 (e.g., ...). Figure 4As shown, the separation test tube 3 is thinner at the top, thicker in the middle, and thinner at the bottom. The heating element 5 is fitted onto the second arc-shaped part 35 and the middle part 32. The heating element 5 is a water bath heater, which mainly heats the second arc-shaped part 35 and the middle part 32 by circulating warm water. Since the urine in the middle part 32 is used to detect heavy metal ions, such as mercury ions, the urine needs to be heated to 50°C for a certain period of time before mercury ion detection. The two sets of pistons 4 are located in the upper part 31 and the lower part 33, respectively. Each of the four components includes a piston head 41 and a first power source 42 (cylinder). The diameter of the piston head 41 is the same as the diameter of the upper part 31. The first power source 42 drives the piston head 41 to move. When the extraction mechanism 14 extracts urine from the urine collection cylinder 11 into the separation test tube 3, the upper piston head 41 moves downward to the first arc-shaped part 34, so that there is a gap between the piston head 41 and the first arc-shaped part 34. The urine flows downward into the middle part 32 of the separation test tube 3. At this time, the lower piston head 41 moves upward to the second arc-shaped part 32. The piston head 41 and the second arc-shaped part 35 are spaced apart, and the urine flows downward into the lower part 33 of the separation test tube 3. When the urine in the lower part 33 reaches a certain height, the lower piston head 41 moves downward to seal between the lower part 33 and the second arc-shaped part 35. When the urine in the middle part 32 reaches a certain height, the upper piston head 41 moves upward to seal between the middle part 32 and the first arc-shaped part 34. At this time, the urine in the separation test tube 3 is divided into upper, middle and lower layers. Compared with setting multiple test tubes to achieve different detections, setting the structure of the separation test tube 3 as the structure of the present invention can achieve different detection methods at the same time, which improves the detection efficiency. Since the urine will evaporate at high temperature, it will affect the bacteria or other components in it. Therefore, a heat insulation plate 43 is provided on the side of the piston head 41 facing the middle part 32, and a sealing structure that contacts the separation test tube 3 is provided on the side of the piston head 41 away from the middle part 32. The sealing structure can be a protruding sealing ring on the piston head 41.

[0043] like Figure 4 and Figure 5As shown, the first detection component 6 includes a detection box 61, a test strip box 62, and a first camera 63. The detection box 61 is horizontally located on one side of the upper part 31 of the separation test tube 3. A flow channel 64 is provided between the upper part 31 and the detection box 61. A paper inlet 65 is provided on the side of the detection box 61 away from the separation test tube 3. A drive roller assembly 66 is also provided on the detection box 61 outside the paper inlet 65 (the drive roller assembly 66 includes a pressing upper roller, a pressing lower roller, and an adsorption roller. The pressing upper roller and the pressing lower roller are coordinated and their purpose is to drive the test strip into or out of the detection box 61. The adsorption roller is located on the side of the pressing upper roller and its purpose is to adsorb and roll the test strip into the channel between the pressing upper roller and the pressing lower roller). The upper surface of the detection box 61 is transparent, and the first camera 63 is located above the detection box 61. The lens is vertically oriented towards the test box 61. The bottom of the test box 61 is provided with a vent for drainage or cleaning. The test strip box 62 is located on one side of the paper inlet 65. Several urine glucose test strips are vertically stacked inside the test strip box 62. The test strip box 62 has a partial opening on the side near the paper inlet 65 and a pushing member on the other side. The test strip box 62 is also provided with a paper-pulling member 67, which consists of a rotating shaft and a lever. One end of the lever is connected to the rotating shaft, and the other end of the lever is provided with a suction nozzle. The paper-pulling member 67 absorbs the test strip at the opening and rotates it to the drive roller group 66. The drive roller group 66 is used to transport part of the test strip into the paper inlet 65. Compared with the fixed test substrate 82, the test substrate 82 in this invention can automatically cooperate with the input, pressing and rinsing of urine residue to automatically repeat the test.

[0044] The principle of its test strip delivery is as follows: When a urine glucose test is required, the piston head 41 at the top of the separating test tube 3 moves upward, pressing the liquid level of the urine in the upper part 31 to be higher than the flow channel 64. At this time, some urine will flow into the test box 61. Before this, the suction nozzle of the paper-pulling component 67 sucks the bottom of the first test strip on the partial opening of the test strip box 62. The paper-pulling component 67 rotates to pull the first test strip out of the test strip box 62 from below, and then rotates again to make the bottom end of the test strip contact the adsorption wheel. When the adsorption wheel rotates clockwise, it will suck the end of the test strip. At this time, the suction nozzle is released, and the test strip is driven by the adsorption wheel to the space between the upper and lower pressing wheels. The rotation of the upper and lower pressing wheels will push the test strip from the paper feed. When the test strip enters the test box 61 through the opening 65, the first two-thirds of the test strip is immersed in the urine in the test box 61, while the last one-third is still located between the upper and lower pressing wheels. After a certain period of immersion, the first camera 63 above will take a downward picture of the color of the test strip to determine the actual range of urine sugar content. After the picture is taken, the upper and lower pressing wheels rotate in opposite directions to pull the test strip out of the test box 61 and drop it into the collection box below as a waste test strip (the collection box is not specified in this invention). The opening at the bottom of the test box 61 will discharge the urine inside into the waste urine container 12, and then the water tank 15 will fill some clean water through the opening for cleaning. The wastewater after cleaning will also be discharged into the waste urine container 12 through the opening.

[0045] like Figure 1 As shown, the detection of mercury ions requires adding reagents such as potassium permanganate to the urine, then bathing it in a 50°C water bath for a certain time, then adding chemical reagents for reduction, and finally extracting a portion for detection by the spectrometer 72. Therefore, the second detection element 7 includes a reagent replenisher 71 and a spectrometer 72. A first collection tube is provided between the spectrometer 72 and the second arc-shaped part 35. The first collection tube is also provided with a replenishment tube that communicates with the reagent replenisher 71. The heating element 5 includes a heating cover, which contains circulating water. A temperature sensor for detecting the temperature of the circulating water is also provided inside the heating cover.

[0046] like Figure 1 and Figure 6 As shown, the third detection component 8 includes an electron microscope 81 and a detection substrate 82. The detection substrate 82 is located on the detection stage of the electron microscope 81. For better hygiene, a urine trough can be set on the detection stage. The detection substrate 82 is placed in the urine trough, so that the urine leaking from the detection substrate 82 will not flow onto the detection stage. The detection substrate 82 includes an upper substrate 821 and a lower substrate 822. Baffles 823 are provided on opposite sides of the lower substrate 822. In addition, collection troughs 824 for collecting wastewater are provided on opposite sides. A urine residue tube communicating with the bottom of the lower part 33 of the separation test tube 3 is provided at the edge of the lower substrate 822. A telescopic column passing through the lower substrate 822 is provided at the bottom of the upper substrate 821. The telescopic column is used to drive the upper substrate 821 to adhere to or move away from the lower substrate 822. Compared with the fixed detection substrate 82, the detection substrate 82 in this invention can automatically cooperate with the input, pressing and rinsing of urine residue to automatically repeat the detection.

[0047] The detection principle is as follows: In the initial state, the telescopic column is in an upward state, and the upper substrate 821 is separated from the lower substrate 822. At this time, the urine residue tube transports the urine residue precipitated at the bottom of the lower part 33 of the separation tube 3 to the lower substrate 822. Since the baffles 823 on both sides can block the urine residue from flowing out from both sides, the telescopic column then presses the upper substrate 821 onto the lower substrate 822. The electron microscope 81 feeds the image back to the system, and the analysis module 102 can analyze the colonies and bacterial count in the image. Then, the upper substrate 821 is raised a certain distance, and the clean water in the water tank 15 is filled from the urine residue tube between the upper substrate 821 and the lower substrate 822 to rinse the urine residue adhering to the upper substrate 821 and the lower substrate 822. The rinsing waste liquid flows into the collection tank 824.

[0048] Before testing for urine glucose, heavy metal ions, and colonies, the color of the urine can be tested first. If the urine color is too dark, there may be other diseases. Therefore, the testing unit 2 also includes a fourth testing element, which includes a second camera located on both sides of the separation unit 1.

[0049] like Figure 2As shown, the urine sample database also includes urine reference color information, which reflects the RGB values ​​of healthy urine.

[0050] The acquisition module 101 acquires the color of the urine in the separation test tube 3 captured by the second camera as the actual color information of the urine;

[0051] The analysis module 102 acquires the actual urine color information from the acquisition module 101 and the urine reference color information from the urine sample database. It compares the actual urine color information with the urine reference color information. If the difference between the two is large, an abnormal command is issued; if the difference between the two is small, a normal command is issued.

[0052] The urine sample database also includes a scoring table and a control range. The scoring table contains the scoring values ​​of each reference information, and the control range reflects the normal score range of urine. The control box 9 also includes a statistics module 103 and a control module 104. The statistics module 103 obtains the scores corresponding to each actual information in the collection module 101, and then calculates the total score according to the weight formula.

[0053] The control module 104 obtains the total score from the statistics module 103 and compares the total score with the control range. If the total score falls within the control range, the control module 14 extracts and transports the urine from the urine collection cylinder 11 to the urine storage cylinder 13. If the total score does not fall within the control range, the control module 14 extracts and transports the urine from the urine collection cylinder 11 to the waste urine cylinder 12.

[0054] For example, in the scoring table, the reference information for urine glucose is A-A' corresponding to t1 score, and A1-A1' corresponding to t2 score; the reference information for heavy metals is B-B' corresponding to u1 score, and B1-B1' corresponding to u2 score; the reference information for bacteria is C-C' corresponding to o1 score, and C1-C1' corresponding to o2 score. The test results for substance A are t2, u2, and o1. Based on the weight ratio of the three, t2*z1 + u2*z2 + o1*z3 is used to obtain the total score. The total score is then compared with the control range to determine the health status of the urine.

[0055] The above are merely preferred embodiments of the present invention. The scope of protection of the present invention is not limited to the above embodiments. All technical solutions falling within the scope of the present invention's concept are within the scope of protection of the present invention. It should be noted that for those skilled in the art, any improvements and modifications made without departing from the principle of the present invention should also be considered within the scope of protection of the present invention.

Claims

1. A urine separation and recovery system for preparing urokinase, characterized in that: The application relates to a separation device, which comprises a separation mechanism (1) and a detection mechanism (2) in the separation device, the separation mechanism (1) comprises a plurality of separation test tubes (3), the separation test tubes (3) comprise two groups of piston members (4), the separation test tubes (3) are filled with urine, the two groups of piston members (4) are used for separating the urine in the separation test tubes (3) into three layers of upper, middle and lower layers, a heating member (5) is arranged on the outer ring of the middle layer of the separation test tubes (3), and the detection mechanism (2) comprises a first detection member (6), a second detection member (7) and a third detection member (8). The separation device is further provided with a control box (9), the control box (9) comprises a urine sample database, the urine sample database comprises urine sugar reference information, heavy metal ion reference information and bacteria reference information, the urine sugar reference information reflects the normal urine sugar content range in urine, the heavy metal ion reference information reflects the normal heavy metal content range in urine, and the bacteria reference information reflects the normal bacteria type and content range in urine. The control box (9) further comprises a collection module (101) and an analysis module (102). The collection module (101) obtains the content of urine sugar in the upper layer of the separation test tube (3) as actual urine sugar information, obtains the content of heavy metal ions in the middle layer of the separation test tube (3) as actual heavy metal information, and obtains the content of bacteria in the lower layer of the separation test tube (3) as actual bacteria information. The analysis module (102) obtains the actual information collected by the collection module (101), obtains the reference information in the urine sample database, compares the actual information with the reference information one by one, and issues an abnormal instruction when any actual information is inconsistent with the corresponding reference information, otherwise, a normal instruction is issued.

2. The urine separation and recovery system for preparing urokinase according to claim 1, wherein: The separation device comprises an upper chamber (111), a middle chamber (112) and a lower chamber (113) which are separated by a partition plate, the separation mechanism (1) and the detection mechanism (2) are located in the middle chamber (112), the upper chamber (111) is further provided with a transfer mechanism (10), the transfer mechanism (10) carries a urine collecting cylinder (11), the lower chamber (113) is provided with a waste urine cylinder (12) and a plurality of urine storage cylinders (13), the inner top of the upper chamber (111) is further provided with an extraction mechanism (14), the extraction mechanism (14) is used for extracting the urine in the urine collecting cylinder (11) into the separation test tube (3) or the urine storage cylinder (13) or the waste urine cylinder (12), one side of the upper chamber (111) is further provided with a water tank (15), and the water tank (15) is provided with cleaning pipelines between the extraction mechanism (14), the separation test tube (3), the first detection mechanism (2), the second detection mechanism (2) and the third detection mechanism (2).

3. The urine separation and recovery system for preparing urokinase according to claim 2, wherein: The separation mechanism (1) further comprises a test tube support (16) horizontally connected to the front and rear sidewalls of the middle chamber (112), and a plurality of insertion holes for fixing the separation test tube (3) are arranged on the test tube support (16); the separation test tube (3) comprises an upper part (31), a middle part (32) and a lower part (33); a first arc-shaped part (34) is arranged at the connection between the upper part (31) and the middle part (32); a second arc-shaped part (35) is arranged at the connection between the middle part (32) and the lower part (33); the diameter of the upper part (31) is the same as that of the lower part (33); the diameter of the middle part (32) is larger than that of the upper part (31); the heating element (5) is sleeved on the second arc-shaped part (35) and the middle part (32); two groups of the piston elements (4) are respectively arranged in the upper part (31) and the lower part (33); each group of the piston elements (4) comprises a piston head (41) and a first power source (42); the diameter of the piston head (41) is the same as that of the upper part (31); the first power source (42) drives the piston head (41) to move.

4. The urine separation and recovery system for preparing urokinase according to claim 3, wherein: A heat insulation sheet (43) is arranged on the side of the piston head (41) facing the middle part (32); and a sealing structure in contact with the separation test tube (3) is arranged on the side of the piston head (41) away from the middle part (32).

5. The urine separation and recovery system for preparing urokinase according to claim 3, wherein: The first detection element (6) comprises a detection box (61), a test paper box (62) and a first camera (63); the detection box (61) is horizontally arranged on one side of the upper part (31) of the separation test tube (3); a flow channel (64) is arranged between the upper part (31) and the detection box (61); an inlet (65) is arranged on the side of the detection box (61) away from the separation test tube (3); a driving roller set (66) is further arranged on the detection box (61) outside the inlet (65); the upper surface of the detection box (61) is transparent; the first camera (63) is arranged above the detection box (61) with the lens vertically facing the detection box (61); a through hole for draining or cleaning is arranged at the bottom of the detection box (61); the test paper box (62) is arranged on one side of the inlet (65); a plurality of urine glucose detection test papers are vertically stacked in the test paper box (62); a partial opening is arranged on the side of the test paper box (62) close to the inlet (65); a test paper pushing element (67) is further arranged on the test paper box (62); the test paper pushing element (67) adsorbs the test papers at the opening and rotates to move to the driving roller set (66); the driving roller set (66) is used for conveying the test papers to the inlet (65).

6. The urine separation and recovery system for preparing urokinase according to claim 3, wherein: The second detection element (7) comprises a reagent replenisher (71) and a spectrometer (72); a first collection tube is arranged between the second arc-shaped part (35) and the spectrometer (72); a replenishment tube in communication with the reagent replenisher (71) is further arranged on the first collection tube; the heating element (5) comprises a heating cover; circulating water is arranged in the heating cover; a temperature sensor for detecting the temperature of the circulating water is further arranged in the heating cover.

7. The urine separation and recovery system for preparing urokinase according to claim 3, wherein: The third detection member (8) comprises an electron microscope (81) and a detection substrate (82), the detection substrate (82) is located on the detection table of the electron microscope (81), the detection substrate (82) comprises an upper substrate (821) and a lower substrate (822), opposite sides of the lower substrate (822) are respectively provided with baffles (823), and the other opposite sides are respectively provided with collection grooves (824) for collecting waste water, an edge of the lower substrate (822) is provided with a urine residue pipe communicated with the bottom of the lower part (33) of the separation test tube (3), and the bottom of the upper substrate (821) is provided with an extension column penetrating through the lower substrate (822), the extension column is used for driving the upper substrate (821) to be close to or away from the lower substrate (822).

8. The urine separation and recovery system for preparing urokinase according to claim 1, wherein: The detection mechanism (2) further comprises a fourth detection member, and the fourth detection member comprises a second camera located on opposite sides of the separation mechanism (1); The urine sample database further comprises urine reference color information, and the urine reference color information reflects the RGB value of healthy urine; The collection module (101) obtains the color of the urine in the separation test tube (3) photographed by the second camera as actual urine color information; The analysis module (102) respectively obtains the actual urine color information in the collection module (101) and the urine reference color information in the urine sample database, compares the actual urine color information with the urine reference color information, and if the deviation is large, an abnormal instruction is sent, and if the deviation is small, a normal instruction is sent.

9. The urine separation and recovery system for preparing urokinase according to claim 8, wherein: The urine sample database further comprises a score table and a score control range, the score table contains the score value of each reference information, and the score control range reflects the normal score value range of urine; the control box (9) further comprises a statistical module (103) and a control module (104), the statistical module (103) obtains the score value corresponding to each actual information in the collection module (101), and then calculates a total score value according to a weight formula; The control module (104) obtains the total score value in the statistical module (103), compares the total score value with the score control range, if the total score value falls within the score control range, controls the extraction mechanism (14) to extract and convey the urine in the urine collecting cylinder (11) into the urine storage cylinder (13), and if the total score value does not fall within the score control range, controls the extraction mechanism (14) to extract and convey the urine in the urine collecting cylinder (11) into the waste urine cylinder (12).

10. The urine separation and recovery system for preparing urokinase according to claim 9, wherein: The extraction mechanism (14) comprises an extraction frame (141) and a plurality of extraction suction heads (142) vertically connected to the extraction frame (141), one end of the extraction suction head (142) is provided with an extension hose for conveying urine, and the extraction frame (141) is provided with a power part for driving the extraction frame (141) to move so that the extraction suction head (142) extends into or moves out of the urine collecting cylinder (11).

Images