A highly adaptable miniaturized microchannel reaction platform device

Abstract

This application relates to a highly adaptable miniaturized microchannel reaction platform device, belonging to the field of microchannel reactors. It includes a fixture and a microreactor chip. The microreactor chip has reaction channels, including raw material inlets and outlets. There are at least two raw material inlets. The fixture is fixed relative to the microreactor chip and has several fluid inlet / outlet channels. A raw material outlet or a single raw material inlet is connected to a corresponding fluid inlet / outlet channel. The fixture includes a base plate and a cover plate connected to each other. The microreactor chip is located between the base plate and the cover plate. The fluid inlet / outlet channels are located on the cover plate. One port of each fluid inlet / outlet channel is located on the side of the cover plate facing the microreactor chip, and the other port is located on the side of the cover plate away from the microreactor chip or on a side adjacent to the surface facing the microreactor chip. This application reduces the processing pressure of the hole structure on the cover plate by staggering the ports of the fluid inlet / outlet channels on different surfaces.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of micro-channel reactors, in particular to a highly adaptive miniaturized micro-channel reaction platform device. BACKGROUND

[0002] Micro-channel reactors are an important branch derived from the development of microfluidic technology, which refers to chemical reaction process equipment with a characteristic scale below 1000 μm. It has the advantages of large specific surface area, small scale-up effect, high mass and heat transfer efficiency, and flow state close to plug flow, so that material residence time can be accurately controlled, process control is energy-saving and safe; it refers to mesoscopic micro-channel reactors with a characteristic size in the range of 1000 μm-3500 μm, which can be used for small-scale, pilot-scale and batch production of chemical reaction processes.

[0003] The Chinese invention application with publication number CN106622064A discloses a micro-mixing chip and a micro-channel reaction system, which comprises a micro-mixing chip, a micro-channel reaction system, wherein the micro-mixing chip is provided with a reaction channel, and the reaction channel is communicated with a plurality of reactant inlets; the micro-channel reaction system comprises a clamp and a heat exchanger, the clamp is used for clamping and mounting the micro-mixing chip on the heat exchanger; the clamp is also provided with flow channel vias for injecting reactants into the reaction channel of the micro-mixing chip, the flow channel vias correspond to the reactant inlets one by one, and the flow channel vias are used for cooperating with the UNF external thread joint, so that the reactants can smoothly enter the micro-reaction chip for mixing or reaction.

[0004] For the related technology in the above, the inventors believe that there are the following defects: when multiple reactants are reacted, the number of reactant inlets of the reaction channel on the micro-reaction chip needs to be increased correspondingly, and the number of flow channel vias on the clamp also needs to be increased correspondingly, but the volume of the clamp is limited, the size of the flow channel via which needs to cooperate with the UNF external thread joint is a fixed value and is not easy to change, so for the micro-channel reaction system with more reactant inlets of the micro-reaction chip, various factors bring inconvenience to the processing of the hole structure of the clamp. SUMMARY

[0005] In order to improve the above problems, the present application provides a highly adaptive miniaturized micro-channel reaction platform device.

[0006] The highly adaptive miniaturized micro-channel reaction platform device provided by the present application adopts the following technical scheme:

[0007] The application discloses a highly adaptive miniaturized micro-channel reaction platform device which comprises a clamp and a micro-reaction chip, the micro-reaction chip is provided with a reaction channel, the reaction channel comprises a raw material inlet and a raw material outlet, the number of the raw material inlets is at least two, the clamp is fixed opposite to the micro-reaction chip, a plurality of fluid inlets and outlets are arranged on the clamp, the raw material outlet or a single raw material inlet is in communication with one fluid inlet and outlet, the clamp comprises a bottom plate and a cover plate which are connected to each other, the micro-reaction chip is located between the bottom plate and the cover plate, the fluid inlets and outlets are arranged on the cover plate, one port of each fluid inlet and outlet is located on the side of the cover plate which faces the micro-reaction chip, and the other port is located on the side of the cover plate which is away from the micro-reaction chip or is located on the side surface adjacent to the side of the cover plate which faces the micro-reaction chip.

[0008] According to the technical scheme, the ports of the fluid inlets and outlets which are away from the micro-reaction chip are arranged on different surfaces of the cover plate, the space resources for arranging the ports of the fluid inlets and outlets which are externally connected with UNF external threads on the cover plate are greatly increased, and the machining pressure of the hole structure on the cover plate is reduced.

[0009] Preferably, the device further comprises a temperature control table which is located on the side of the bottom plate which is away from the micro-reaction chip and is detachably connected with the clamp, the temperature control table comprises a base and a sealing plate which are detachably connected with each other, a medium groove is arranged on the side of the base which faces the sealing plate, a hot refrigerant inlet and outlet is arranged on the base and is in communication with the medium groove, the clamp is detachably connected to the side of the sealing plate which is away from the base, an isolation strip is fixedly connected to the base and is located in the medium groove, the isolation strip abuts against the groove bottom of the medium groove and the sealing plate respectively, and a plurality of hot refrigerant inlets and outlets are arranged on the base and are in communication with the opposite sides of the isolation strip.

[0010] According to the technical scheme, different hot refrigerant media are introduced into the two regions, different temperature zones are formed on the sealing plate, and the micro-reaction chips in the clamp in the different temperature zones can perform micro-reactions under different temperature conditions.

[0011] Preferably, the number of the hot refrigerant inlets and outlets which are in communication with one side of the isolation strip is two, a flow extension protrusion is fixedly connected to the base and is located in the medium groove, one end of the flow extension protrusion is located on the same surface groove wall of the two hot refrigerant inlets and outlets in the medium groove, and a plurality of medium protrusions are fixedly connected to the groove bottom of the medium groove and are in contact with the side of the sealing plate which faces the base.

[0012] According to the technical scheme, the flow extension protrusion is used for increasing the flow distance of the hot refrigerant in the medium groove, so that the temperature distribution uniformity of the corresponding temperature zone is improved, the medium protrusions shear, divide and stagger the flow of the hot refrigerant medium, the distribution range of the stagnation boundary layer of the hot refrigerant medium in the flow process in the temperature zone is reduced, the heat transfer film coefficient is improved, the thermal resistance is reduced, and the heat transfer efficiency is improved.

[0013] Preferably, the micro-reaction chip comprises two glass plates fixedly connected with each other through thermal bonding, and reaction grooves are formed on the sides of the two glass plates facing each other, the reaction grooves on the two glass plates are mirror images, the grooves of the two reaction grooves are opposite to each other and form a reaction channel, and a bonding exhaust hole is formed on the glass plate.

[0014] By using the above technical scheme, the bonding exhaust hole can improve the fitting degree of the plate surface during the bonding connection of the two glass plates.

[0015] Preferably, the reaction groove comprises a feeding channel, a mixing channel and a discharging channel connected in sequence, a plurality of reaction portions are connected between the mixing channel and the discharging channel, the feeding channel is connected with a raw material inlet, the discharging channel is connected with a raw material outlet, and a plurality of feeding channels are provided, and the width of the end of the feeding channel facing the mixing channel is tapered.

[0016] By using the above technical scheme, the tapered channel can refine the fluid and prolong the residence time of the material, and the tapered channel width can strengthen the mass transfer efficiency.

[0017] Preferably, a shunt structure is arranged in an array at the mixing channel, and the shunt structure is used for repeatedly shunting and combining the mixture.

[0018] By using the above technical scheme, the material is repeatedly shunted and combined under the action of the shunt structure in the initial stage of mixing, and the mixing degree between different materials is improved.

[0019] Preferably, a plurality of reaction portions are connected in sequence, the trajectory of the reaction portion is a curve, and the width of the channel between adjacent reaction portions is tapered.

[0020] Preferably, the reaction portion is a differential shunt channel arranged side by side.

[0021] Preferably, a viewing window is formed in the cover plate, and an LED surface light source plate is detachably connected to the side of the cover plate away from the bottom plate.

[0022] By using the above technical scheme, the LED surface light source plate is installed on the placing shell and turned on, which provides light source for the micro-reaction chip, creates the required conditions for chemical reactions that require light source catalytic conditions, enriches the types of micro-channel reactions that can be carried out in the reaction channel, and when no light source is added, the operator can directly observe the reaction in the micro-reaction chip through the viewing window.

[0023] Preferably, the clamp further comprises a mounting bolt, the LED surface light source plate comprises a connecting portion and a working plate, the mounting bolt passes through the connecting portion, the cover plate and the bottom plate in sequence, the working plate is fixedly connected with the LED lamp on the side facing the micro-reaction chip, a power supply interface is arranged on the connecting portion, and the working plate is detachably and slidably connected with the connecting portion.

[0024] In summary, the present application has at least one of the following beneficial technical effects:

[0025] 1. By arranging the partial fluid inlet and outlet channels away from the ports of the micro-reaction chip on different surfaces of the cover plate, the space resources of the cover plate for a certain number of fluid inlet and outlet channels are greatly increased, and the pressure of the hole structure processing on the cover plate is reduced.

[0026] 2. By arranging the LED surface light source plate connected to the clamp cover plate, the LED lamp can transmit light to the micro-reaction chip through the window, and provide necessary experimental conditions for the micro-reaction under the need of photocatalysis conditions.

[0027] 3. The medium groove of the temperature control table is divided into two areas by the isolation strip, different hot and cold media are introduced into the two areas, different temperature zones are formed on the cover plate, and the micro-reaction chips in the clamps in different temperature zones can perform micro-reactions under different temperature conditions. BRIEF DESCRIPTION OF DRAWINGS

[0028] Figure 1 is the overall structure schematic diagram of the high-adaptability micro-reaction platform device in the embodiment of the present application.

[0029] Figure 2 is the structure schematic diagram of the micro-reaction chip for prolonging the residence time of materials in the embodiment of the present application.

[0030] Figure 3 is Figure 2 is the partial enlarged view of part A in

[0031] Figure 4 is the structure schematic diagram of another micro-reaction chip for prolonging the residence time of materials in the embodiment of the present application.

[0032] Figure 5 is the structure schematic diagram of the micro-reaction chip for gas participation or two-phase difficultly soluble material in the embodiment of the present application.

[0033] Figure 6 is Figure 5 is the partial enlarged view of part B in

[0034] Figure 7 is the structure schematic diagram of the temperature control table base in the embodiment of the present application.

[0035] Figure 8 This is a schematic diagram illustrating the structure of the fixture in the embodiments of this application.

[0036] Figure 9 This is a schematic diagram illustrating the structure of the cover plate facing the microreactor chip in the embodiments of this application.

[0037] Figure 10 This is a structural schematic diagram used to illustrate the base plate in the embodiments of this application.

[0038] Figure 11 This is a schematic diagram illustrating the fluid inflow and outflow of the cover plate in an embodiment of this application.

[0039] Figure 12 This is a schematic diagram illustrating the structure of the fixture after connecting the LED surface light source board in the embodiments of this application.

[0040] Figure 13 This is a schematic diagram illustrating the structure of the LED surface light source board in the embodiments of this application.

[0041] Explanation of reference numerals in the attached drawings: 1. Fixture; 11. Base plate; 12. Cover plate; 121. Viewing window; 13. Placement half-groove; 131. Placement cavity; 14. Mounting bolt; 15. Fluid inlet / outlet channel; 2. LED surface light source board; 21. Connecting part; 211. Power interface; 212. Adjusting slide; 213. Positioning guide groove; 214. Conductive contact; 215. Anti-reverse groove; 216. Anti-reverse protrusion; 22. Working plate; 221. Contact guide post; 222. Anti-reverse post; 23. LED light; 3. Micro-reflector 31. Chip; 31. Reaction channel; 311. Raw material inlet; 312. Raw material outlet; 313. Feed channel; 314. Mixing channel; 3141. Diversion structure; 315. Discharge channel; 316. Reaction section; 317. Fourth material channel; 32. Glass plate; 321. Bonding vent; 4. Temperature control platform; 41. Sealing plate; 42. Base; 421. Medium tank; 422. Isolation strip; 423. Sealing ring; 424. Hot and cold medium inlet and outlet; 425. Flow extension strip; 426. Medium boss. Detailed Implementation

[0042] The following is in conjunction with the appendix Figures 1-13 This application will be described in further detail.

[0043] This application discloses a highly adaptable miniaturized microchannel reaction platform device, such as... Figure 1 As shown, it includes a temperature control platform 4, a fixture 1, and a microreactor chip 3; the microreactor chip 3 provides the necessary environment for the microreaction, the fixture 1 is used to clamp and fix the microreactor chip 3 on the temperature control platform 4, and the temperature control platform 4 provides the necessary temperature conditions for the microreactor chip 3.

[0044] As shown in Figure 2 The micro-reaction chip 3 is composed of two glass plates 32 fixedly connected with each other by thermal bonding. Before the glass plates 32 are fixedly connected with each other, reaction grooves are formed on the plate surfaces of the glass plates 32. When the reaction groove openings of the two glass plates 32 face each other, the two reaction grooves are mirror images of each other. After the two glass plates 32 are buckled, the reaction groove openings of the two reaction grooves face each other and form a reaction channel 31 for the reaction material to flow through. The one glass plate 32 is provided with a raw material inlet 311 and a raw material outlet 312. The specific structure of the reaction groove includes a feeding channel 313, a mixing channel 314 and a discharging channel 315 connected in sequence. A plurality of reaction portions 316 are connected between the mixing channel 314 and the discharging channel 315. The number of the feeding channels 313 is greater than two. The number of the raw material inlets 311 is consistent with the number of the feeding channels 313 and they are connected one by one. The discharging channel 315 is connected with the raw material outlet 312. The manufacturing process of the micro-reaction chip 3 is as follows: two glass etching plates with mirror image arranged reaction grooves are obtained by wet etching. After removing the residual chrome plating layer and plating glue layer on the surface, the laser ablation method is used to cut the outer shape frame and perform the round corner processing. The glass plate 32 is punched (the raw material inlet 311 and the raw material outlet 312). Then the glass etching mirror image plate with processed shape, punched and rounded corners is cleaned to the surface clean. Then it is placed into a vacuum drying box at 120°C for 2h for thermal bonding. The total time of thermal bonding and annealing is 24h. After thermal bonding, the glass plate is polished by cloth. The finished product is obtained. In order to improve the close fit of the two glass plates 32 during bonding, the glass plate 32 is provided with a bonding exhaust hole 321.

[0045] As shown in Figure 2 , 3 and 4, the number of the raw material inlets 311 and the feeding channels 313 on the micro-reaction chip 3 is two to four. After the reaction material enters the reaction channel 31 from the raw material inlet 311, it flows into the mixing channel 314 for preliminary mixing, and then further mixed and reacted in the reaction portion 316. Therefore, the width of each feeding channel 313 gradually decreases towards the end of the mixing channel 314. The mixing channel 314 is provided with a shunt structure 3141 for repeatedly shunting and fusing the raw material mixture.

[0046] As shown in Figure 2 and 3 The micro-reaction chip 3 for prolonging the residence time of the material. The number of the raw material inlets 311 and the feeding channels 313 is two. The shunt structure 3141 in the mixing channel 314 is a cylinder fixedly connected to the bottom of the reaction groove. The reaction portion 316 is a crescent-shaped flow channel structure, i.e. its trajectory is a curve, and the width of the channel between the adjacent two reaction portions 316 is gradually reduced. Thus, the fluid can be refined, the residence time of the material can be prolonged, and the mass transfer efficiency can be enhanced at the gradually reduced channel width.

[0047] As shown in Figure 4As shown, the micro-reaction chip 3 is also used for prolonging the residence time of materials, the distribution structure 3141 and the setting of the reaction part 316 are the same as the previous paragraph, and the number of raw material inlets 311 and feed channels 313 is three; and on this basis, a fourth material channel 317 is additionally arranged between the reaction parts 316, the quenching agent can be added to the reaction channel 31 through the fourth material channel 317, and the communication part of the fourth material channel 317 and the reaction channel 31 is also designed as a necked opening.

[0048] As shown in Figure 5 and 6 , the micro-reaction chip 3 is used for gas participation or two-phase immiscible material, the number of feed inlets is two, and the ports of the two feed channels 313 communicating with the mixing channel 314 are arranged opposite to each other, the distribution structure 3141 is a plurality of channel branches intersecting with each other in a mesh shape, and the reaction part 316 is a differential flow channel arranged side by side, the trajectory of the differential flow channel is a wave shape, which is helpful to reduce the size of the gas film and improve the mass transfer and diffusion efficiency of the two-phase immiscible material.

[0049] As shown in Figure 1 and 7 , the temperature control table 4 includes a base 42 and a cover plate 41 which are detachably connected by bolts, the side of the base 42 facing the cover plate 41 is provided with a medium groove 421 for the hot coolant medium to flow through. The base 42 is fixedly connected with a partition strip 422 in the medium groove 421, the partition strip 422 abuts against the middle groove bottom of the medium groove 421 and the side of the cover plate 41 facing the base 42, which divides the medium groove 421 into two independent temperature zones; the base 42 is provided with hot coolant inlets and outlets 424, the hot coolant inlets and outlets 424 are communicated with the medium groove 421, the hot coolant inlets and outlets 424 are provided with two pairs of four, and the two pairs of hot coolant inlets and outlets 424 are communicated with the opposite sides of the partition strip 422 respectively. The side of the base 42 facing the cover plate 41 and around the medium groove 421 is fixedly connected with a sealing ring 423, which is used to improve the sealing performance of the medium groove 421. The materials of the base 42 and the cover plate 41 are both 6061-T6 aluminum alloy, the thickness of the cover plate 41 is 4mm, the hot coolant is water or CS0.65 silicone oil, and the materials of the partition strip 422 and the sealing ring 423 are both silicone grease.

[0050] As shown in Figure 7As shown, a pair of hot and cold medium inlets and outlets 424 corresponding to a temperature zone of a medium tank 421 are located on the same tank wall. A flow-extending protrusion 425 is integrally formed on the base 42 within each temperature zone of the medium tank 421. One end of the flow-extending protrusion 425 is connected to the same tank wall of the hot and cold medium inlets and outlets 424 and located between the two hot and cold medium inlets and outlets 424. This protrusion is used to increase the flow path of the hot and cold medium within the medium tank 421, thereby improving the temperature distribution uniformity of the corresponding temperature zone. Simultaneously, several medium bosses 426 are integrally formed on the base 42 at the bottom of the medium tank 421. The medium bosses 426 are cylindrical, and their tops contact the side of the sealing plate 41 facing the base 42. The medium bosses 426 shear, divide, and cross-flow the hot and cold medium, reducing the distribution range of the stagnant boundary layer during the flow of the hot and cold medium within the temperature zone, increasing the heat transfer film coefficient, reducing thermal resistance, and thus improving heat transfer efficiency. Meanwhile, the cylindrical bosses, due to the fewer dead angles they form with the surrounding flow channels, are more conducive to reducing fluid pressure drop when a large flow of hot or cold media is introduced.

[0051] like Figure 1 , 7 As shown in Figure 8, the sealing plate 41 has a threaded hole on the side away from the base 42 for mounting the clamp 1. The clamp 1 includes a cover plate 12, a base plate 11, and mounting bolts 14. Both the base plate 11 and the cover plate 12 have placement half-grooves 13 of the same size and shape formed on their opposite sides. After the base plate 11 and the cover plate 12 are fitted together, the two placement half-grooves 13 are connected and combined to form a placement cavity 131. The micro-reaction chip 3 is placed in the placement cavity 131, and the surface of the micro-reaction chip 3 is in contact with the bottom of the placement half-grooves 13. A viewing window 121 is provided in the middle of the cover plate 12, which connects the bottom of the placement half-grooves 13 to the side of the cover plate 12 away from the base plate 11. The mounting bolts 14 pass through the cover plate 12 and the base plate 11 in sequence and are then screwed onto the temperature control console 4, thereby connecting the housing to the temperature control console 4. At this time, the viewing window 121 is located on the upper surface of the housing, allowing the operator to observe the reaction within the reaction channel 31. The cover plate 12 can be made of perfluorinated materials such as PFA, FEP, ETFE, or PCTFE, which are resistant to corrosion from most chemicals. The base plate 11 does not contact the reaction fluid and only needs to ensure heat transfer efficiency; therefore, it is made of 6061-T6 aluminum alloy. In this embodiment, eight clamps 1 can be installed on the cover plate 12, with four clamps 1 positioned above the same temperature zone.

[0052] like Figure 9 , 10As shown in FIG. 11, five fluid access channels 15 are formed in the cover plate 12, one of the ports of the fluid access channels 15 is located at the bottom of the half-slot 13, and each fluid access channel 15 is in one-to-one correspondence with the raw material outlet 312 or the raw material inlet 311 of the micro-reaction chip 3, i.e., the five ports of the fluid access channels 15 are arranged in a line. The other port of the fluid access channel 15 is a UNF screw thread interface for inserting a UNF inverted taper joint, two UNF screw thread interfaces are located on the side of the cover plate 12 away from the bottom plate 11, and three UNF screw thread interfaces are located on the side surface of the cover plate 12 adjacent to the side surface facing the micro-reaction chip 3. The fluid access channels 15 with ports located on different surfaces of the cover plate 12 are alternately arranged, so as to alleviate the problem of inconvenient machining of the hole structure of the cover plate 12 caused by excessive concentration of the screw thread interfaces.

[0053] As shown in FIG. 12, Figure 12 and 13 For chemical reactions requiring photocatalytic conditions, the clamp 1 can selectively configure the LED surface light source plate 2. The LED surface light source plate 2 is detachably connected to the side of the cover plate 12 away from the bottom plate 11, and for one of the micro-channel reactions requiring light source catalysis, the LED surface light source plate 2 can be installed in advance on the placing shell. The LED surface light source plate 2 includes a connecting portion 21 and a working plate 22, the connecting portion 21 is provided with holes for the installation bolts 14 to pass through, the installation bolts 14 pass through the connecting portion 21 first, and finally make the opposite sides of the connecting portion 21 abut against the cover plate 12 and the nuts of the installation bolts 14. The connecting portion 21 is provided with a power interface 211 for inserting the power line terminal, and the working plate 22 is fixedly connected with the LED lamp 23, and the working plate 22 is movably connected with the connecting portion 21 and is detachably electrically connected.

[0054] As shown in FIG. 13, Figure 12 and 13As shown, the adjusting slide 212 is arranged on the connecting part 21, the adjusting slide 212 is arranged at two opposite sides of the window 121, the length direction of the adjusting slide 212 is parallel to the plate surface of the cover plate 12, the opposite ends of one edge of the working plate 22 are fixedly connected with the contact guide posts 221, the LED lamp 23 is electrically connected with the contact guide posts 221, and the working plate 22 is slidably connected with the connecting part 21 by sliding in the adjusting slide 212 through the contact guide posts 221. One end of the adjusting slide 212 penetrates to the edge of the connecting part 21, and the end is an access end, and the other end is a conductive end; the positioning guide groove 213 is arranged on the side wall of the adjusting slide 212 close to the side of the cover plate 12, the positioning guide groove 213 is inclined to the side away from the retreat stop groove 215 relative to the length direction of the adjusting slide 212; the conductive contact 214 is fixedly connected with the power supply interface 211 on the connecting part 21 and at the groove bottom of the positioning guide groove 213, the conductive contact 214 is electrically connected with the power supply interface 211, and after the working plate 22 is slid relative to the connecting part 21 and the contact guide posts 221 are moved into the positioning guide groove 213, the conductive contact 214 is in contact with the contact guide posts 221, and at this time, the power supply interface 211 is electrically connected with the LED lamp 23 through the conductive contact 214 and the contact guide posts 221.

[0055] As Figure 12 and 13As shown, the light irradiance of the LED surface light source plate 2 can reach 100 mw / cm^2, and with 365 nm ultraviolet light, 405 nm ultraviolet light, 455 nm blue light, which will cause serious damage to the human retina. The exit end of the adjusting slide 212 and the side wall close to the cover plate 12 are provided with a retreat groove 215, and the side wall of the retreat groove 215 is fixedly connected with a retreat protrusion 216 at the communication position of the adjusting slide 212. The working plate 22 is fixedly connected with a retreat column 222, when the contact column 221 slides into the positioning guide groove 213, the retreat column 222 is above the retreat groove 215, press the working plate 22 downward, the retreat column 222 crosses the retreat protrusion 216 and enters the retreat groove 215, the retreat protrusion 216 abuts against the side wall of the retreat column 222, thereby realizing the retreat limiting of the whole working plate 22; and when the retreat protrusion 216 is located in the retreat groove 215 and the contact column 221 is located in the positioning guide groove 213, the side of the working plate 22 facing the micro-reaction chip 3 is attached to the surface of the cover plate 12 away from the bottom plate 11, and the LED lamp 23 is completely located in the opening range of the viewing window 121, that is, the power is turned on at this time, the LED lamp 23 is turned on, and the light emitted by the LED lamp 23 can be completely shot into the viewing window 121. At the same time, the edge of the working plate 22 away from the contact column 221 is located outside the surface projection area of the cover plate 12, so that the edge of the working plate 22 can provide a force point for the removal of the working plate 22; when it is necessary to observe the reaction in the micro-reaction chip 3, the working plate 22 is pulled out by applying a pulling force, the viewing window 121 is opened, and the LED lamp 23 is turned off and extinguished, thereby reducing the damage of strong light to the human body.

[0056] The implementation principle of the high-adaptability micro-reaction platform device is as follows:

[0057] The clamps 1 clamping different types of micro-reaction chips 3 are installed on the cover plate 41 in sequence, which can be connected in series through the fluid inlet and outlet channel 15 to complete various complex chemical reaction processes, or can be used in parallel to simultaneously perform different types of chemical reaction processes, or can be used to increase the production capacity of the chemical reaction process target.

[0058] The above are preferred embodiments of the present application, which do not limit the protection scope of the present application, therefore: any equivalent changes made on the structure, shape and principle of the present application shall be covered within the protection scope of the present application.

Claims

1. A highly adaptive miniaturized microchannel reaction platform device, comprising a clamp (1) and a micro-reaction chip (3), the micro-reaction chip (3) is provided with a reaction channel (31), the reaction channel (31) comprises a raw material inlet (311) and a raw material outlet (312), the number of the raw material inlet (311) is at least two, the clamp (1) is fixed opposite to the micro-reaction chip (3), the clamp (1) is provided with a plurality of fluid inlet and outlet channels (15), the raw material outlet (312) or a single raw material inlet (311) is in communication with one fluid inlet and outlet channel (15), characterized in that: The clamp (1) comprises a bottom plate (11) and a cover plate (12) connected with each other, the micro-reaction chip (3) is located between the bottom plate (11) and the cover plate (12), the fluid inlet and outlet channels (15) are arranged on the cover plate (12), one port of each fluid inlet and outlet channel (15) is located on the side of the cover plate (12) facing the micro-reaction chip (3), and the other port is located on the side of the cover plate (12) away from the micro-reaction chip (3) or the side adjacent to the surface of the side facing the micro-reaction chip (3); the temperature control table (4) is located on the side of the bottom plate (11) away from the micro-reaction chip (3) and is detachably connected with the clamp (1), the temperature control table (4) comprises a base (42) and a cover plate (41) detachably connected with each other, a medium groove (421) is arranged on the side of the base (42) facing the cover plate (41), a hot refrigerant inlet and outlet (424) is arranged on the base (42) and communicates with the medium groove (421); the clamp (1) is detachably connected to the side of the cover plate (41) away from the base (42), an isolation strip (422) is fixedly connected to the base (42) and located in the medium groove (421), the isolation strip (422) abuts against the groove bottom of the medium groove (421) and the cover plate (41) respectively, and the hot refrigerant inlet and outlet (424) is provided with a plurality of hot refrigerant inlet and outlet (424) and communicates with the opposite sides of the isolation strip (422); the number of the hot refrigerant inlet and outlet (424) communicating with one side of the isolation strip (422) is two, a flow extension protruding strip (425) is fixedly connected to the base (42) and located in the medium groove (421), one end of the flow extension protruding strip (425) is located on the same plane groove wall of the two hot refrigerant inlets and outlets (424) in the medium groove (421), and the groove bottom of the medium groove (421) is fixedly connected with a plurality of medium protruding columns (426), the top end of the medium protruding column (426) is in contact with the side of the cover plate (41) facing the base (42); the micro-reaction chip (3) comprises two glass plates (32) fixedly connected with each other through thermal bonding, the side of each glass plate (32) facing the other glass plate (32) is provided with a reaction groove, and the reaction grooves on the two glass plates (32) are mirror images, the grooves of the two reaction grooves are opposite to each other and form a reaction channel (31), and a bonding exhaust hole (321) is arranged on the glass plate (32); the reaction groove comprises a feeding channel (313), a mixing channel (314) and a discharging channel (315) communicated in sequence, a plurality of reaction parts (316) are communicated between the mixing channel (314) and the discharging channel (315), the feeding channel (313) communicates with a raw material inlet (311), the discharging channel (315) communicates with a raw material outlet (312), and the feeding channel (313) is provided with a plurality of feeding channels (313), and the width of the end of each feeding channel (313) facing the mixing channel (314) gradually decreases. ​ 2. The highly adaptable miniaturized microchannel reaction platform device of claim 1, wherein: The mixing channel (314) is provided with a plurality of flow splitting structures (3141) for repeatedly splitting and fusing the raw material mixture.

3. The highly adaptable miniaturized microchannel reaction platform device of claim 1, wherein: A plurality of reaction sections (316) are sequentially communicated, the reaction section (316) is a crescent-shaped flow channel structure, the track of the reaction section (316) flow channel structure is a curve, and the width of the channel between adjacent reaction sections (316) is gradually reduced.

4. The highly adaptive miniaturized microchannel reaction platform device of claim 1, wherein: The reaction section (316) is a differential flow channel arranged side by side, and the flow dividing structure (3141) is a plurality of channel branches intersecting each other in a mesh shape.

5. The highly adaptive miniaturized microchannel reaction platform device of claim 1, wherein: A window opening (121) is formed in the cover plate (12), and an LED surface light source plate (2) is detachably connected to the side of the cover plate (12) away from the bottom plate (11).

6. The highly adaptive miniaturized microchannel reaction platform device of claim 5, wherein: The clamp (1) further comprises a mounting bolt (14), the LED surface light source plate (2) comprises a connecting portion (21) and a working plate (22), the mounting bolt (14) sequentially penetrates the connecting portion (21), the cover plate (12) and the bottom plate (11), an LED lamp (23) is fixedly connected to the side of the working plate (22) facing the micro-reaction chip (3), a power supply interface (211) is formed in the connecting portion (21), the working plate (22) is detachably slidably connected with the connecting portion (21), and the LED lamp (23) is electrically connected with the power supply interface (211).

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