A pushing device and a control method thereof, and a pushing dyeing machine

By using the sample addition unit and the imaging unit of the slide pusher to detect the sample on the glass slide in real time, the problem of repetitive operation when the smear is unqualified is solved, and the operation process is simplified and time is saved.

CN116124546BActive Publication Date: 2025-11-28SHENZHEN REETOO BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202211622004.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-12-16
Publication Date
2025-11-28
Estimated Expiration
2042-12-16

AI Technical Summary

Technical Problem

In the existing technology, if the smear formed by the slide pushing operation is not qualified, the slide pushing and staining operations need to be repeated, which makes the operation process time-consuming.

Method used

A slide pushing device is provided, including a sample addition unit, a slide pushing unit, and an imaging unit. The sample addition unit is controlled by a control unit to perform the first sample addition operation, and the sample is judged to meet the preset standard based on the image to be tested on the slide. If it does not meet the standard, a second sample addition operation is performed, which simplifies the operation process.

Benefits of technology

By detecting the sample on the slide in real time in the slide pusher, the need to transfer the slide to the slide reader for detection is avoided, simplifying the operation process and reducing time consumption.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application provides a slide pushing device and a control method thereof and a slide dyeing machine. The slide pushing device comprises: a sample adding unit configured to perform a first sample adding operation to add a sample to a slide; a slide pushing unit configured to perform a slide pushing operation to apply the sample to the slide; a photographing unit configured to acquire a to-be-detected image of the slide before the slide pushing operation and / or after the slide pushing operation; and a control unit in communication connection with the sample adding unit, the slide pushing unit and the photographing unit, respectively. The control unit is configured to control the sample adding unit to perform the first sample adding operation, and to detect whether the sample on the slide meets a preset standard according to the to-be-detected image. When the sample does not meet the preset standard, the control unit controls the sample adding unit to perform a second sample adding operation. Compared with the prior art, the slide does not need to be transported to a slide reading instrument for detection, the whole operation process is simplified, and time consumption is reduced.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a slide pushing device, a control method thereof and a slide pushing and dyeing machine. BACKGROUND

[0002] In the diagnosis and treatment of diseases, a sample is applied to a slide to form a smear through slide pushing operation, and then the smear is dyed to complete the preparation of the slide, and finally the sample on the prepared slide is detected to obtain a detection result, which provides a reference for the doctor's diagnosis of the disease. In order to ensure the accuracy of the detection result, the prepared slide also needs to be detected before the sample on the prepared slide is detected to determine whether the prepared slide is qualified.

[0003] In the prior art, the prepared slide after dyeing operation is detected in a slide reading instrument. This method will result in the need to re-perform slide pushing operation and dyeing operation if the smear formed by slide pushing operation is unqualified, and the whole operation process is relatively long. SUMMARY

[0004] The present application mainly provides a slide pushing device, a control method thereof and a slide pushing and dyeing machine, which can simplify the whole operation process and reduce the time consumption.

[0005] To solve the above technical problems, one technical solution adopted by the present application is to provide a slide pushing device, which comprises: a sample adding unit configured to perform a first sample adding operation to add a sample to a slide; a slide pushing unit configured to perform a slide pushing operation to apply the sample to the slide; a photographing unit configured to acquire a to-be-detected image of the slide before and / or after the slide pushing operation; and a control unit in communication connection with the sample adding unit, the slide pushing unit and the photographing unit, respectively. The control unit is configured to control the sample adding unit to perform a first sample adding operation, and to detect whether the sample on the slide meets a preset standard according to the to-be-detected image, so that when the sample does not meet the preset standard, the control unit controls the sample adding unit to perform a second sample adding operation.

[0006] In a specific embodiment, the slide pushing device further comprises a conveying unit, the conveying unit comprising a conveying driving mechanism and a conveying bearing mechanism, the conveying driving mechanism being connected with the conveying bearing mechanism to drive the conveying bearing mechanism to move, the conveying bearing mechanism being configured to carry the slide, a sample adding position and a slide pushing position being provided along a movement track of the conveying bearing mechanism, the sample adding unit being configured to perform a sample adding operation at the sample adding position, and the slide pushing unit being configured to perform a slide pushing operation at the slide pushing position.

[0007] In an embodiment, the sample adding unit is configured to perform a first sample adding operation to add the sample onto the first slide, and the photographing unit is configured to detect whether the sample on the first slide meets the preset standard before the slide pushing operation and / or after the slide pushing operation, so that when the sample does not meet the preset standard, the sample adding unit performs a second sample adding operation to add the sample onto the second slide.

[0008] In an embodiment, the slide includes a first slide pushing area and a second slide pushing area, the sample adding unit is configured to perform a first sample adding operation to add the sample onto the first slide pushing area, and the photographing unit is configured to detect whether the sample on the first slide pushing area meets the preset standard before the slide pushing operation and / or after the slide pushing operation, so that when the sample does not meet the preset standard, the sample adding unit performs a second sample adding operation to add the sample onto the second slide pushing area.

[0009] In an embodiment, the sample adding unit includes a sample adding power element and a sample adding member, the sample adding power element is in communication with the sample adding member, the sample adding power element is configured to collect the sample through the sample adding member for the first time, and perform a first sample adding operation to add the first collected sample onto the slide, the sample adding power element is further configured to collect the sample through the sample adding member for the second time when the sample of the first sample adding operation does not meet the preset standard, and perform a second sample adding operation to add the second collected sample onto the slide, or the sample adding power element is configured to collect the sample through the sample adding member, and perform a first sample adding operation to add part of the collected sample onto the slide, the sample adding power element is further configured to perform a second sample adding operation through the sample adding member to add another part of the collected sample onto the slide when the sample of the first sample adding operation does not meet the preset standard.

[0010] In an embodiment, the sample adding unit further includes a cleaning swab, the sample adding power element is further configured to discharge the remaining sample in the sample adding member when the sample meets the preset standard, and the cleaning swab is configured to clean the sample adding member.

[0011] In an embodiment, the conveying unit further includes a pushing driving mechanism and a pushing member, the pushing driving mechanism is connected with the pushing member, so that when the sample on the first slide does not meet the preset standard, the pushing driving mechanism drives the pushing member to push the first slide out of the conveying and carrying mechanism.

[0012] In an embodiment, the slide pushing device further includes a recycling unit, the recycling unit is configured to recycle the first slide pushed out of the conveying and carrying mechanism.

[0013] In an embodiment, a printing position is further arranged along the movement track of the conveying carrier mechanism, and the push slide device further comprises a printing unit, which is configured to perform slide printing on the first slide at the printing position when the sample on the first slide does not meet the preset standard, so as to form a detection mark on the first slide.

[0014] In an embodiment, the push slide device further comprises a transfer unit, which is configured to receive the first slide on the conveying carrier mechanism when the sample on the first slide does not meet the preset standard, so as to transfer the first slide to a slide basket.

[0015] In an embodiment, the push slide device further comprises a mixing unit, which is configured to mix the sample in the sample container, and the sample adding power element is configured to collect the mixed sample in the sample container by the sample adding element for the first time, and collect the mixed sample in the sample container for the second time when the sample collected for the first time does not meet the preset standard.

[0016] In an embodiment, the push slide device further comprises a clamping unit, which comprises a clamping driving mechanism and a clamping assembly, the clamping driving mechanism is connected with the clamping assembly to drive the clamping assembly to move, and a clamping position and a mixing receiving position are arranged along the movement track of the clamping assembly, the clamping assembly is configured to clamp the sample container at the clamping position, and the mixing unit is configured to receive the sample container clamped by the clamping assembly at the mixing receiving position.

[0017] In an embodiment, the push slide device further comprises a sample feeding unit, which is configured to convey the sample container, and a container receiving position, the clamping position and a container recycling position are arranged along the conveying track of the sample feeding unit in sequence, and the clamping driving mechanism is further configured to drive the clamping assembly to clamp the sample container collected for the second time to the clamping position, so that the sample feeding unit conveys the sample container collected for the second time to the recycling position.

[0018] To solve the above technical problems, another technical solution adopted by the present application is to provide a push slide staining machine, characterized in that the push slide staining machine comprises a staining device and the push slide device, and the staining device is configured to stain the slide meeting the preset standard.

[0019] In a specific embodiment, the staining device comprises a staining unit for performing first staining on the slide meeting the preset standard, and a detection unit for detecting whether the slide after the first staining meets the preset condition, so that when the slide after the first staining does not meet the preset condition, the staining unit performs second staining on the slide meeting the preset standard, or the sample adding unit performs third sample adding operation to add sample to another slide.

[0020] To solve the above technical problems, the application adopts another technical solution: providing a control method of the slide pushing device, the control method comprising: controlling the sample adding unit to perform first sample adding operation to add sample to a slide; controlling the photographing unit to acquire a to-be-detected image of the slide before and / or after the slide pushing operation; detecting whether the sample on the slide meets a preset standard according to the to-be-detected image, so that when the sample does not meet the preset standard, the control unit controls the sample adding unit to perform second sample adding operation.

[0021] The application has the following beneficial effects: different from the prior art, the slide pushing device provided by the embodiment of the application comprises: a sample adding unit for performing first sample adding operation to add sample to a slide; a slide pushing unit for performing slide pushing operation to spread the sample on the slide; a photographing unit for acquiring a to-be-detected image of the slide before and / or after the slide pushing operation; and a control unit in communication connection with the sample adding unit, the slide pushing unit and the photographing unit, respectively, the control unit being configured to control the sample adding unit to perform first sample adding operation, and detect whether the sample on the slide meets a preset standard according to the to-be-detected image, so that when the sample does not meet the preset standard, the control unit controls the sample adding unit to perform second sample adding operation, compared with the prior art, the slide does not need to be transported to a slide reading instrument for detection, the whole operation process is simplified, and time consumption is reduced. BRIEF DESCRIPTION OF DRAWINGS

[0022] In order to more clearly illustrate the technical solutions in the embodiments of the application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the application, and other drawings can be obtained by those skilled in the art without creative effort.

[0023] Figure 1 is a schematic diagram of the three-dimensional assembly structure of the slide pushing device provided by the application;

[0024] Figure 2 is Figure 1 is a schematic diagram of the three-dimensional exploded structure of the slide pushing device in

[0025] Figure 3 is Figure 2 Schematic diagram of the three-dimensional assembly structure of the sample adding unit in the middle;

[0026] Figure 4 is Figure 3 Schematic diagram of the principle of the sample adding unit in the middle;

[0027] Figure 5 is Figure 2 Schematic diagram of the three-dimensional assembly structure of the push piece unit in the middle;

[0028] Figure 6 is Figure 1 Schematic diagram of the position of the push piece device in the middle;

[0029] Figure 7 is Figure 1 Schematic diagram of the control of the push piece device in the middle;

[0030] Figure 8 is Figure 2 Schematic diagram of the three-dimensional structure of the conveying unit in the middle;

[0031] Figure 9 is Figure 2 Schematic diagram of the three-dimensional assembly structure of the sample adding unit, mixing unit and clamping unit in the middle;

[0032] Figure 10 is Figure 2 Schematic diagram of the three-dimensional structure of the transfer unit in the middle;

[0033] Figure 11 is the schematic diagram of the three-dimensional structure of the push piece dyeing machine provided in the present application;

[0034] Figure 12 is Figure 11 Schematic diagram of the exploded structure of the dyeing device in the middle;

[0035] Figure 13 is the flowchart of the control method of the push piece device provided in the present application. DETAILED DESCRIPTION

[0036] The present application will be further described in detail below in conjunction with the drawings and embodiments. It is particularly pointed out that the following embodiments are only used to illustrate the present application, but do not limit the scope of the present application. Similarly, the following embodiments are only part of the embodiments of the present application, but not all embodiments. All other embodiments obtained by those of ordinary skill in the art without creative labor are within the scope of protection of the present application.

[0037] The terms "first", "second", "third", etc. are used only for descriptive purposes and are not to be construed as indicating or implying relative importance or a specific number of the indicated technical characteristics. Thus, features defined with "first", "second" or "third" can explicitly or implicitly include at least one of the features. In the description of the present application, the meaning of "a plurality of" is at least two, such as two, three, etc., unless otherwise explicitly and specifically limited. All directional references (such as upper, lower, left, right, front, back, etc.) in the present application are only used for explanatory purposes and are not to be construed as indicating or implying relative importance or specific number of the indicated technical characteristics. In addition, the terms "comprise" and "have" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device that includes a list of steps or units is not limited to the listed steps or units, but can optionally include other steps or units not listed, or can optionally include other steps or units inherent to the process, method, product or device.

[0038] In this document, reference to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase "in an embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are they necessarily mutually exclusive of one another. It is expressly understood that any of the embodiments described herein can be combined with any of the other embodiments.

[0039] Please refer to Figure 1 and Figure 2 , Figure 1 is a schematic diagram of the assembled structure of the push piece device 10 according to the embodiment of the application, Figure 2 is Figure 1 a schematic diagram of the exploded structure of the push piece device 10 in

[0040] Please refer to Figure 3 and Figure 4 , Figure 3 is Figure 2 a schematic diagram of the assembled structure of the sample adding unit 11 in Figure 4 is Figure 3A schematic diagram of the principle of the sample adding element 152, the sample adding unit 11 is used to perform the first sample adding operation to add the sample to the slide 110. The sample adding unit 11 includes a sample adding power element 111 and a sample adding element 112, the sample adding power element 111 is in communication with the sample adding element 112. In the embodiment, the sample adding element 112 includes a sample adding needle 1121 and a sample adding tube 1122, the sample adding power element 111 is in communication with the sample adding tube 1122, and the sample adding tube 1122 is in communication with the sample adding needle 1121, so that the sample adding power element 111 performs the sample collection and sample adding operation through the sample adding needle 1121.

[0041] Further, the sample adding unit 11 in the embodiment further includes a first sample adding driving mechanism 113 and a second sample adding driving mechanism 114, the sample adding element 112 is installed on the second sample adding driving mechanism 114, and the first sample adding driving mechanism 113 is connected with the second sample adding driving mechanism 114, so that the first sample adding driving mechanism 113 drives the sample adding element 112 to move away from or close to the slide 110 in a first sample adding direction E, and the second sample adding driving mechanism 114 drives the sample adding element 112 to move away from or close to the slide 110 in a second sample adding direction F.

[0042] Please refer to Figure 5 and Figure 6 , Figure 5 is Figure 2 a perspective assembly structure diagram of the push piece unit 12, Figure 6 is Figure 1 a position schematic diagram of the push piece device 10, the push piece unit 12 is used to perform the push piece operation to apply the sample to the slide 110.

[0043] The push piece unit 12 includes a push piece driving mechanism 121 and a push piece mounting mechanism 122, the push piece mounting mechanism 122 is used to install the push piece 120, and the push piece driving mechanism 121 is connected with the push piece mounting mechanism 122 to drive the push piece 120 to perform the push piece operation to apply the sample to the slide 110.

[0044] In the embodiment, the push piece driving mechanism 121 includes a first push piece driving assembly 1211 and a second push piece driving assembly 1212, the first push piece driving assembly 1211 is connected with the push piece mounting mechanism 122, and the second push piece driving assembly 1212 is connected with the first push piece driving assembly 1211, so that the first push piece driving assembly 1211 drives the push piece 120 to move in a first push piece direction A, and the second push piece driving assembly 1212 drives the push piece 120 to move in a second push piece direction B, thereby completing the push piece operation. In the embodiment, the first push piece direction A is a vertical direction, and the second push piece direction B is a horizontal direction.

[0045] Optionally, in the embodiment, the first push piece driving assembly 1211 and the second push piece driving assembly 1212 both adopt the driving mode of a lead screw motor, and in other embodiments, other driving modes can also be adopted, such as a cylinder, which is not limited.

[0046] Please refer to Figure 6 and Figure 7 , Figure 7 are Figure 1 a control schematic diagram of the push piece device 10, and the photographing unit 13 is configured to acquire a to-be-detected image of the slide 110 before the push piece operation and / or after the push piece operation.

[0047] Further, the push piece device 10 in the embodiment further includes a control unit 100, which is in communication connection with the sample adding unit 11, the push piece unit 12 and the photographing unit 13 respectively, and the control unit 100 is configured to control the sample adding unit 11 to perform a first sample adding operation, and to detect whether the sample on the slide meets a preset standard according to the to-be-detected image, so that when the sample does not meet the preset standard, the control unit 100 controls the sample adding unit 11 to perform a second sample adding operation.

[0048] For example, the photographing unit 13 is configured to detect whether the sample on the slide 110 meets the preset standard before the push piece operation, and after the sample adding unit 11 performs the first sample adding operation, the photographing unit 13 performs a first detection, if the sample on the slide 110 meets the preset standard, the push piece unit 12 can perform a first push piece operation, if the sample on the slide 110 does not meet the preset standard, the sample adding unit 11 performs a second sample adding operation, and then the photographing unit 13 performs a second detection, and so on.

[0049] For another example, the photographing unit 13 is configured to detect whether the sample on the slide meets the preset standard after the push piece operation, and after the sample adding unit 11 performs the first sample adding operation, the push piece unit 12 performs a first push piece operation, and then the photographing unit 13 performs a first detection, if the sample on the slide 110 meets the preset standard, subsequent operations such as dyeing the slide 110 can be performed, if the sample on the slide 110 does not meet the preset standard, the sample adding unit 11 performs a second sample adding operation, and then the push piece unit 12 performs a second push piece operation, and the photographing unit 13 performs a second detection, and so on.

[0050] Through the above-mentioned manner, compared with the prior art, the slide does not need to be transported to the film reading instrument for detection, the whole operation process is simplified, and the time consumption is reduced.

[0051] Optionally, if the photographing unit 13 is used to detect whether the sample on the slide meets the preset standard before the pushing operation, the photographing unit 13 can specifically detect one or more information of the length, width, area, diffusion speed of the sample, so as to judge whether the sample meets the preset standard according to one or more of the information; if the photographing unit 13 is used to detect whether the sample on the slide meets the preset standard after the pushing operation, the photographing unit 13 can specifically detect one or more characteristics of the color, appearance, area, whether there is a bubble after the sample is applied, so as to judge whether the sample meets the preset standard according to one or more of the characteristics.

[0052] Please refer to Figure 6 and Figure 8 , Figure 8 is Figure 2 the schematic diagram of the three-dimensional structure of the conveying unit 14 in the slide pushing device 10, the slide pushing device 10 in the embodiment further includes a conveying unit 14, the conveying unit 14 includes a conveying driving mechanism 141 and a conveying bearing mechanism 142, the conveying driving mechanism 141 is connected with the conveying bearing mechanism 142 to drive the conveying bearing mechanism 142 to move, and the sample adding position P1 and the slide pushing position P2 are arranged along the movement track of the conveying bearing mechanism 142.

[0053] The sample adding unit 11 is used to perform the sample adding operation at the sample adding position P1, that is, to perform the first sample adding operation described above at the sample adding position P1 or to sequentially perform the first sample adding operation and the second sample adding operation described above at the sample adding position P1, and the slide pushing unit 12 performs the slide pushing operation at the slide pushing position P2, that is, to perform the first slide pushing operation described above at the slide pushing position P2 or to sequentially perform the first slide pushing operation and the second slide pushing operation described above at the slide pushing position P2.

[0054] It can be understood that the specific position of the photographing unit 13 can be set according to actual conditions, for example, if the photographing unit 13 is used to detect whether the sample on the slide 110 meets the preset standard after the slide pushing operation, the photographing unit 13 directly detects whether the sample on the slide 110 meets the preset standard at the slide pushing position P2 after the slide pushing operation of the slide pushing unit 12 is completed, or the photographing unit 13 detects whether the sample on the slide 110 meets the preset standard at other positions after the slide pushing operation of the slide pushing unit 12 is completed, and the conveying driving mechanism 141 drives the conveying bearing mechanism 142 to move the slide 110 to other positions, which is not limited.

[0055] In an optional embodiment, if the photographing unit 13 detects that the sample does not meet the preset standard, the sample adding unit 11 performs the first sample adding operation and the second sample adding operation on the same slide 110. For example, the photographing unit 13 is configured to detect whether the sample on the slide 110 meets the preset standard after the pushing operation. After the sample adding unit 11 performs the first sample adding operation at the sample adding position P1, the conveying driving mechanism 141 drives the conveying bearing mechanism 142 to move the slide 110 to the pushing position P2. The slide pushing unit 12 performs the first pushing operation at the pushing position P2. Then, the photographing unit 13 performs the first detection. If the sample on the slide 110 does not meet the preset standard, the conveying driving mechanism 141 drives the conveying bearing mechanism 142 to return the slide 110 to the sample adding position P1. The sample adding unit 11 performs the second sample adding operation at the sample adding position P1. The conveying driving mechanism 141 drives the conveying bearing mechanism 142 to move the slide 110 to the pushing position P2 again. The slide pushing unit 12 performs the second pushing operation at the pushing position P2. In this case, the two pushing operations of the slide pushing unit 12 are performed on the same slide 110.

[0056] In the optional embodiment, the slide 110 includes a first pushing area 1101 and a second pushing area 1102. The sample adding unit 11 is configured to perform the first sample adding operation to add the sample to the first pushing area 1101. The photographing unit 13 is configured to detect whether the sample in the first pushing area 1101 meets the preset standard before the pushing operation and / or after the pushing operation. In this way, when the sample does not meet the preset standard, the sample adding unit 11 performs the second sample adding operation to add the sample to the second pushing area 1102. In this case, although the sample adding unit 11 performs the first sample adding operation and the second sample adding operation on the same slide 110, the sample is added to different areas on the slide 110.

[0057] In another optional embodiment, if the photographing unit 13 detects that the sample does not meet the preset standard, the sample adding unit 11 performs the first sample adding operation and the second sample adding operation on different slides 110.

[0058] Specifically, the conveying bearing mechanism 142 is configured to carry a first slide and a second slide. The sample adding unit 11 is configured to perform the first sample adding operation to add the sample to the first slide. The photographing unit 13 is configured to detect whether the sample on the first slide meets the preset standard before the pushing operation and / or after the pushing operation. In this way, when the sample does not meet the preset standard, the sample adding unit 11 performs the second sample adding operation to add the sample to the second slide. In this case, if the photographing unit 13 is configured to detect whether the sample on the slide 110 meets the preset standard after the pushing operation, the slide pushing unit 12 performs the first pushing operation on the first slide and performs the second pushing operation on the second slide.

[0059] It can be understood that the first slide and the second slide described above can be the same type of slide, or can be different types of slides, and the first slide and the second slide are only artificially named for differentiation, and are not limited.

[0060] In a specific application scenario, the sample adding power element 111 is configured to collect a sample through the sample adding element 112 for the first time, and perform a first sample adding operation to add the sample collected for the first time to the slide 110. The sample adding power element 111 is further configured to collect a sample through the sample adding element 112 for the second time when the sample collected for the first time does not meet the preset standard, and perform a second sample adding operation to add the sample collected for the second time to the slide 110. For example, the sample adding power element 111 adds the sample collected for the first time and the sample collected for the second time to the same slide 110 described above in sequence, or adds the sample collected for the first time to the first slide described above and adds the sample collected for the second time to the second slide described above.

[0061] It can be understood that in the specific application scenario, the sample adding unit 11 performs two sample collection operations and two sample adding operations.

[0062] In another specific application scenario, the sample adding power element 111 is configured to collect a sample through the sample adding element 112, and perform a first sample adding operation to add part of the collected sample to the slide. The sample adding power element is further configured to perform a second sample adding operation through the sample adding element when the sample collected for the first time does not meet the preset standard, to add another part of the collected sample to the slide. For example, the sample adding power element 111 adds part of the collected sample and another part of the collected sample to the same slide 110 described above in sequence, or adds part of the collected sample to the first slide described above and adds another part of the collected sample to the second slide described above.

[0063] It can be understood that in the other specific application scenario, the sample adding unit 11 only performs one sample collection operation and two sample adding operations.

[0064] Further, the sample adding unit 11 further includes a cleaning swab 115, and the sample adding power element 111 is further configured to discharge the remaining sample in the sample adding element 112 when the sample meets the preset standard, and the cleaning swab 115 is configured to clean the sample adding element.

[0065] Further, when the conveying carrier 142 is used to carry the first slide and the second slide as described above, the conveying unit 14 further comprises a pushing driving mechanism 143 and a pushing piece 144, the pushing driving mechanism 143 is connected with the pushing piece 144, so that when the sample on the first slide does not meet the preset standard, the pushing driving mechanism 143 drives the pushing piece 144 to push the first slide out of the conveying carrier 142, so that the conveying carrier 142 receives the second slide after the first slide is pushed out.

[0066] Optionally, the slide pushing device 10 further comprises a recycling unit 15, the recycling unit 15 is used to recycle the first slide pushed out of the conveying carrier 142.

[0067] Optionally, the recycling unit 15 comprises a recycling body 151 and a mounting body 152, the recycling body 151 is used to recycle the first slide and is movably connected with the mounting body 152, so that the recycling position of the recycling body 151 is adjustable, for example, the mounting body 152 is a slide rail in the embodiment, and the recycling body 151 is mounted on the slide rail and is slidably connected with the slide rail.

[0068] Further, the recycling body 151 comprises a recycling bin 1511 and a guide piece 1512, the recycling bin 1511 is movably connected with the mounting body 152, and the recycling bin 151 is formed with a recycling space 101 and a first opening 102 communicating with the recycling space, the guide piece 1512 is formed with a recycling channel 103, and the extension direction C of the recycling channel 103 is arranged to be inclined relative to the opening direction D of the second opening 102, so that the first slide falls into the recycling space 101 along the recycling channel 103, in the embodiment, the opening direction D of the second opening 102 is a vertical direction, and when the first slide slides from the recycling channel 103 to the recycling space 101, the first slide falls into the recycling space 101 along the recycling channel 103 under the action of gravity.

[0069] Further referring to Figure 2 and Figure 6 , the slide pushing device 10 in the embodiment further comprises a slide storage unit 16.

[0070] Optionally, the slide storage unit 16 is used to store the slide 110, and the conveying carrier 142 is used to receive the slide 110 at the slide receiving position P3.

[0071] Please refer to Figure 2 and Figure 9 , Figure 9 is Figure 2A schematic diagram of the three-dimensional assembly structure of the sample adding unit 11, the mixing unit 17, and the clamping unit 18. The push piece device 10 in this embodiment further comprises a mixing unit 17, which is used to mix the sample in the sample container 130. The sample adding power element 111 is used to collect the mixed sample in the sample container 130 by the sample adding element 112 for the first time, and to collect the mixed sample in the sample container 130 for the second time when the sample collected for the first time does not meet the preset standard.

[0072] Specifically, the sample container 130 contains the sample that needs to be pushed and operated. The mixing unit 17 first mixes the sample in the sample container 130. After mixing, the sample adding power element 111 collects the sample in the sample container 130 through the sample adding element 112. When the sample adding unit 11 collects the sample twice, the sample adding power element 111 collects the sample in the sample container 130 for the first time and for the second time through the sample adding element 112.

[0073] In actual application, after the sample adding unit 11 completes the sample collection operation on the sample container 130, the sample container 130 needs to be removed from the mixing unit 17. Therefore, in the prior art, the detection of the prepared sample is performed after the push piece operation and the dyeing operation. Because the entire operation process takes a long time, if the push piece operation needs to be performed again, the sample container 130 needs to be placed on the mixing unit 17 again, and then the sample adding unit 11 can perform the second sample collection operation. In this embodiment, because the photographing unit 13 detects the sample on the slide before and / or after the push piece operation, the entire operation process takes a short time. Therefore, if the second sample collection operation is needed, the sample adding unit 11 can perform the second sample collection operation before the sample container 130 is removed from the mixing unit 17, without the need to remove the sample container 130 and then place it on the mixing unit 17 again, thereby further simplifying the operation process and reducing the time consumption.

[0074] Further, the push piece device 10 in this embodiment further comprises a clamping unit 18, which comprises a clamping driving mechanism 181 and a clamping assembly 182. The clamping driving mechanism 181 is connected with the clamping assembly 182 to drive the clamping assembly 182 to move. A clamping position P4 and a mixing receiving position P5 are arranged along the movement track of the clamping assembly 182. The clamping assembly 182 is used to clamp the sample container 130 at the clamping position P4, and the mixing unit 17 is used to receive the sample container 130 clamped by the clamping assembly 182 at the mixing receiving position P5. In this way, if the second sample collection operation is needed, the sample container 130 does not need to be clamped to the mixing receiving position P5 by the clamping unit 18 compared with the prior art.

[0075] Specifically, before the sample in the sample container 130 is mixed by the mixing unit 17, the clamping driving mechanism 181 drives the clamping assembly 182 to move to the clamping position P4. After the sample container 130 is clamped by the clamping assembly 182, the clamping driving mechanism 181 drives the clamping assembly 182 to move the sample container 130 to the mixing receiving position P5, so that the sample in the sample container 130 is mixed by the mixing unit 17.

[0076] Further, the slide pushing device 10 in the embodiment further comprises a sample feeding unit 19, the sample feeding unit 19 is used for conveying the sample container 130, and the conveying track of the sample feeding unit 19 is sequentially provided with the container receiving position P6, the clamping position P4 and the container recycling position P7. The clamping driving mechanism 181 is further used for driving the clamping assembly 182 to clamp the sample container 130 after the second sampling to the clamping position P4, so that the sample feeding unit 19 conveys the sample container 130 after the second sampling to the recycling position P8.

[0077] Specifically, the sample feeding unit 19 receives the sample container 130 at the container receiving position P6 and conveys the sample container 130 to the clamping position P4. Then, the clamping unit 18 clamps the sample container 130 to the mixing receiving position P5. After the sample in the sample container 130 is sampled by the sample adding unit 11, the clamping unit 18 clamps the sample container 130 from the mixing receiving position P5 to the clamping position P4. Finally, the sample feeding unit 19 conveys the sample container 130 to the container recycling position P7. In the embodiment, since the photographing unit 13 detects the sample on the slide before and / or after the slide pushing operation, the whole operation process takes a short time. Therefore, the sample feeding unit 19 conveys the sample container 130 from the clamping position P4 to the container recycling position P7 after the second sample sampling operation, so that the sample feeding unit 19 in the embodiment only needs to perform a sample feeding operation once, further simplifying the operation process and reducing the time consumption.

[0078] Further referring to Figure 2 and Figure 6 , the slide pushing device 10 in the embodiment further comprises a printing unit 10a, and the printing position P8 is further provided along the movement track of the conveying bearing mechanism 132. The printing unit 10a is used for performing slide printing on the first slide at the printing position P8.

[0079] For example, as described above, the conveying bearing mechanism 142 is used for bearing the first slide and the second slide, and the printing unit 10a is used for performing slide printing on the first slide at the printing position P8 when the sample on the first slide does not meet the preset standard, so as to form a detection mark on the first slide, thereby distinguishing the first slide through the detection mark and reducing the difficulty of distinguishing.

[0080] Please refer to Figure 10 , Figure 10 is Figure 2Fig. 6 is a schematic view of the perspective structure of the transfer unit 10b. The slide pushing device 10 in the embodiment further comprises a transfer unit 10b, which is used to receive the first slide on the conveying bearing mechanism 142 when the sample on the first slide does not meet the preset standard, so that the first slide is transferred to the slide basket.

[0081] For example, the photographing unit 13 is used to detect whether the sample meets the preset standard after the slide pushing operation. If the sample on the first slide does not meet the preset standard, the transfer unit 10b receives the first slide, so that the first slide is transferred to the slide basket, thereby eliminating the need for subsequent staining operation of the first slide.

[0082] The transfer unit 10b comprises a pushing assembly 100a and a transfer assembly 100b. The pushing assembly 100a comprises a pushing driving mechanism 1000a and a pushing piece 1000b. The pushing driving mechanism 1000a is connected with the pushing piece 1000b to drive the pushing piece 1000b to push the first slide from the conveying bearing mechanism 142 to the transfer assembly 100b, so that the first slide is transferred to the slide basket.

[0083] Further referring to Figure 2 , Figure 6 and Figure 8 The slide pushing device 10 in the embodiment further comprises a container transmission unit 10c. The container transmission unit 10 is used to receive the sample container 130 clamped by the clamping unit 18. For example, the clamping unit 18 clamps the sample container after the mixing unit 17 completes the mixing operation to the container transmission unit 10c.

[0084] The container transmission unit 10c is provided with a sampling position P9 along the conveying track. When the container transmission unit 10 receives the sample container 130 clamped by the clamping unit 18, the sample container 130 is transmitted to the sampling position P9. The sampling unit 11 collects the sample in the sample container 110 at the sampling position P9.

[0085] Further, the container transmission unit 10c is further provided with a cap pulling position P10. The slide pushing device 10 in the embodiment further comprises a cap pulling unit 10d, which is used to pull out the container cap on the sample container 130 at the cap pulling position P10.

[0086] Specifically, when the container conveying unit 10 receives the sample container 130 clamped by the clamping unit 18, the sample container 130 is first conveyed to the cap removing position P10, so that the cap removing unit 10d removes the container cap on the sample container 130, and then the container conveying unit 10 conveys the sample container 130 to the sampling position P9. By removing the cap, on the one hand, the sample container 130 does not need to be punctured by a puncture needle before sampling, which avoids the wear of the sample adding member 112 during the puncture process, and simplifies the structure of the sample adding unit 11. On the other hand, the sample adding member 112 can complete the sampling and sample adding operation, and the sample does not need to flow in the pipeline, which avoids the dilution of the sample, thereby affecting the effect of the push piece.

[0087] Optionally, in the embodiment, the mixing unit 17 mixes the sample in the sample container 130 by rotating mixing, and the sample adding unit 11 in the embodiment is also used for suction and suction mixing of the sample in the sample container 130.

[0088] Specifically, in actual application, different types of samples need to be mixed in different ways. For example, if the sample in the sample container 130 is a peripheral blood sample, the sample adding unit 11 can be used for suction and suction mixing. If the sample in the sample container 130 is a conventional blood sample, the mixing unit 17 can be used for swing rotation operation. Therefore, in actual application, the corresponding mixing mode can be selected according to the type of the sample.

[0089] Further, the push piece device 10 in the embodiment further includes a net weaving unit 10e, and the net weaving unit 10e is arranged along the movement track of the sample adding member 112. When the sample needs to be dyed with a net weaving red dye, the sample adding unit 11 adds the collected sample to the net weaving unit 10e, so that the net weaving unit 10e dyes the sample with a net weaving red dye. After the dyeing is completed, the sample adding unit 11 collects the sample in the net weaving unit 10e and adds the sample to the slide 110 at the sample adding position P1.

[0090] Please refer to Figure 11 and Figure 12 , Figure 11 is a perspective structural schematic diagram of an embodiment of the push piece dyeing machine 20 provided in the application, Figure 12 is Figure 11 an exploded structural schematic diagram of the dyeing device 21 in the embodiment, and the push piece dyeing machine 20 in the embodiment includes the dyeing device 21 and the push piece device 10 in the above-mentioned embodiment.

[0091] The staining device 21 is used to stain the slide that meets the preset standard. For example, if the sample on the first slide does not meet the preset standard and the sample on the second slide meets the preset standard, the staining device 21 only needs to stain the second slide and does not need to stain the first slide.

[0092] The staining device 21 includes a staining unit 211 and a detection unit 212. The staining unit 211 is used to perform first staining on the slide that meets the preset standard. The detection unit 212 is used to detect whether the slide after the first staining meets the preset condition. For example, the detection unit 212 is used to detect the staining transmittance of the slide, the number of cells, and the like. Therefore, the preset condition can be set according to the actual situation, and no limitation is made to this.

[0093] In an optional embodiment, when the detection unit 212 detects that the slide after the first staining does not meet the preset condition, the staining unit 211 performs second staining on the slide that meets the preset standard, that is, the staining unit 211 re-stains the slide.

[0094] In another optional embodiment, when the detection unit 212 detects that the slide after the first staining does not meet the preset condition, the sample adding unit 11 performs third sample adding operation to add the sample to another slide, that is, the sample adding unit 11 re-performs the sample adding operation, and then performs the slide pushing operation of the slide pushing unit 12 and the detection operation of the photographing unit 13 described in the above embodiment.

[0095] It can be understood that the third sample adding operation is only named for distinguishing the first sample adding operation and the second sample adding operation, and does not mean that it is the third sample adding operation. For example, in actual application, when the sample after the first sample adding operation of the sample adding unit 11 meets the preset standard, the third sample adding operation is actually the second sample adding operation. The detection unit 212 can use the same principle as the photographing unit 13 described above, or can use other ways, such as a microscope scanning way, an optical coupling detection way, and the like.

[0096] Further, when the detection unit 212 detects that the slide after the first staining meets the preset condition, other operations can be performed on the slide, such as drying, transferring the slide to a slide basket after drying, and waiting for the slide to be read by a slide reading instrument.

[0097] Please refer to Figure 13 , Figure 13 is a flowchart of an embodiment of a control method of the slide pushing device 10 provided in the application. The control method includes the following steps.

[0098] S110: Control the sample adding unit to perform first sample adding operation to add the sample to the slide;

[0099] S120: controlling the photographing unit to acquire a to-be-detected image of the slide before the pushing operation and / or after the pushing operation;

[0100] S130: detecting whether the sample on the slide meets a preset standard according to the to-be-detected image, so that when the sample does not meet the preset standard, the control unit controls the sample adding unit to perform a second sample adding operation.

[0101] It can be understood that the principles of the above steps can refer to the specific description in the embodiment of the slide pushing device 10, and will not be repeated here.

[0102] Unlike the prior art, the slide pushing device provided by the embodiment of the application includes: a sample adding unit for performing a first sample adding operation to add a sample to a slide; a slide pushing unit for performing a slide pushing operation to spread the sample on the slide; a photographing unit for acquiring a to-be-detected image of the slide before the slide pushing operation and / or after the slide pushing operation; and a control unit in communication connection with the sample adding unit, the slide pushing unit, and the photographing unit, respectively. The control unit is used to control the sample adding unit to perform a first sample adding operation, and to detect whether the sample on the slide meets a preset standard according to the to-be-detected image. When the sample does not meet the preset standard, the control unit controls the sample adding unit to perform a second sample adding operation. Compared with the prior art, the slide does not need to be transported to a slide reading instrument for detection, the entire operation process is simplified, and the time consumption is reduced.

[0103] The above only describes some embodiments of the application, and does not limit the protection scope of the application. Any equivalent device or equivalent process transformation using the content of the specification and drawings, or direct or indirect application in other related technical fields, is also included in the patent protection scope of the application.

Claims

1. A pusher device, characterized in that The push piece device comprises: a sample adding unit configured to perform a first sample adding operation to add a sample onto a slide; a push piece unit configured to perform a push piece operation to apply the sample onto the slide; a photographing unit configured to acquire a to-be-detected image of the slide before the push piece operation and / or after the push piece operation; a control unit communicatively connected with the sample adding unit, the push piece unit and the photographing unit, respectively, and configured to control the sample adding unit to perform a first sample adding operation, and to detect whether the sample on the slide meets a preset standard according to the to-be-detected image, so that when the sample does not meet the preset standard, the control unit controls the sample adding unit to perform a second sample adding operation; the push piece device further comprises a conveying unit, the conveying unit comprising a conveying driving mechanism and a conveying bearing mechanism, the conveying driving mechanism being connected with the conveying bearing mechanism to drive the conveying bearing mechanism to move, the conveying bearing mechanism being configured to carry the slide, a sample adding position and a push piece position being arranged along a movement track of the conveying bearing mechanism, the sample adding unit being configured to perform a sample adding operation at the sample adding position, and the push piece unit being configured to perform a push piece operation at the push piece position; the slide comprises a first push piece area and a second push piece area, the sample adding unit is configured to perform a first sample adding operation to add a sample to the first push piece area, and the photographing unit is configured to detect whether the sample in the first push piece area meets a preset standard before the push piece operation and / or after the push piece operation, so that when the sample does not meet the preset standard, the sample adding unit performs a second sample adding operation to add the sample to the second push piece area; or the conveying bearing mechanism is configured to carry a first slide and a second slide, the sample adding unit is configured to perform a first sample adding operation to add a sample to the first slide, and the photographing unit is configured to detect whether the sample on the first slide meets a preset standard before the push piece operation and / or after the push piece operation, so that when the sample does not meet the preset standard, the sample adding unit performs a second sample adding operation to add a sample to the second slide.

2. The tab device of claim 1, wherein The sample adding unit comprises a sample adding power element and a sample adding piece, and the sample adding power element is in communication with the sample adding piece; the sample adding power element is configured to collect the sample through the sample adding piece for a first time, to perform a first sample adding operation to add the sample collected for the first time to the slide, and to collect the sample through the sample adding piece for a second time when the sample collected for the first time does not meet a preset standard, and to perform a second sample adding operation to add the sample collected for the second time to the slide; or the sample adding power element is configured to collect the sample through the sample adding piece, to perform a first sample adding operation to add part of the sample collected to the slide, and to perform a second sample adding operation through the sample adding piece when the sample collected for the first sample adding operation does not meet a preset standard, to add another part of the sample collected to the slide.

3. The tab device of claim 2, wherein The sample adding unit further comprises a cleaning swab, and the sample adding power element is further used to discharge the remaining sample in the sample adding element when the sample meets the preset standard, and the cleaning swab is used to clean the sample adding element.

4. The tab device of claim 1, wherein The conveying unit further comprises a pushing driving mechanism and a pushing element, the pushing driving mechanism is connected with the pushing element, so that when the sample on the first slide does not meet the preset standard, the pushing driving mechanism drives the pushing element to push the first slide out of the conveying bearing mechanism.

5. The tab device of claim 4, wherein, The slide pushing device further comprises a recycling unit, and the recycling unit is used to recycle the first slide pushed out of the conveying bearing mechanism.

6. The tab device of claim 1, wherein, A printing position is further arranged along the movement track of the conveying bearing mechanism, and the slide pushing device further comprises a printing unit, the printing unit is used to perform slide printing on the first slide at the printing position when the sample on the first slide does not meet the preset standard, so as to form a detection mark on the first slide.

7. The tab device of claim 1, wherein, The slide pushing device further comprises a transfer unit, and the transfer unit is used to receive the first slide on the conveying bearing mechanism when the sample on the first slide does not meet the preset standard, so that the first slide is transferred to a slide basket.

8. The tab device of claim 2, wherein, The slide pushing device further comprises a mixing unit, and the mixing unit is used to mix the sample in the sample container, and the sample adding power element is used to sequentially collect the mixed sample in the sample container for the first time through the sample adding element, and collect the mixed sample in the sample container for the second time through the sample adding element when the sample collected for the first time does not meet the preset standard.

9. The tab device of claim 8, wherein, The slide pushing device further comprises a clamping unit, the clamping unit comprises a clamping driving mechanism and a clamping assembly, the clamping driving mechanism is connected with the clamping assembly to drive the clamping assembly to move, a clamping position and a mixing receiving position are arranged along the movement track of the clamping assembly, the clamping assembly is used to clamp the sample container at the clamping position, and the mixing unit is used to receive the sample container clamped by the clamping assembly at the mixing receiving position.

10. The tab device of claim 9, wherein, The slide pushing device further comprises a sample feeding unit, the sample feeding unit is used to convey the sample container, a container receiving position, the clamping position and a container recycling position are sequentially arranged along the conveying track of the sample feeding unit, and the clamping driving mechanism is further used to drive the clamping assembly to clamp the sample container collected for the second time to the clamping position, so that the sample feeding unit conveys the sample container collected for the second time to the recycling position.

11. A push-through dyeing machine, characterized in that The slide pushing and dyeing machine comprises a dyeing device and the slide pushing device according to any one of claims 1-10, and the dyeing device is used to dye the slide meeting the preset standard.

12. The slide stainer of claim 11, wherein, The dyeing device comprises a dyeing unit and a detection unit, the dyeing unit is used to dye the slide meeting the preset standard for the first time, the detection unit is used to detect whether the slide after the first dyeing meets the preset condition, so that when the slide after the first dyeing does not meet the preset condition; the dyeing unit dyes the slide meeting the preset standard for the second time; or the sample adding unit performs a third sample adding operation to add the sample onto another slide.

13. A control method for the pusher device according to any one of claims 1 to 10, characterized in that, The control method comprises: controlling the sample adding unit to perform a first sample adding operation to add the sample onto a slide; controlling the photographing unit to acquire a to-be-detected image of the slide before the slide pushing operation and / or after the slide pushing operation; detecting whether the sample on the slide meets a preset standard according to the to-be-detected image, so that when the sample does not meet the preset standard, the sample adding unit is controlled to perform a second sample adding operation.

Citation Information

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