Thrombectomy device

Abstract

The present application relates to a kind of thrombectomy device, including thrombectomy stent, the thrombectomy stent includes intercepting net and the multiple intercepting pieces that are spaced apart along the circumference of intercepting net and are arranged on the intercepting net, the proximal end of each intercepting piece is connected with the intercepting net, and the distal end is free end;In natural state, the multiple intercepting pieces are located in the outside of the intercepting net, and each intercepting piece is folded outward from the end connected with the intercepting net, and the outward folded part can be folded to the distal end in stretched state;Or, in natural state, the multiple intercepting pieces are located in the inside of the intercepting net, and in stretched state, the multiple intercepting pieces do not cross in radial direction.This thrombectomy device is advantageous to improve single thrombectomy amount.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of interventional medical devices, and in particular to a thrombus removal device. BACKGROUND

[0002] The background section provided herein is merely for information and is not necessarily prior art.

[0003] Pulmonary embolism (PE) refers to a clinical and pathophysiological syndrome caused by endogenous or exogenous emboli blocking the pulmonary artery or its branches, causing pulmonary circulation disorders. The most common and main type is pulmonary thromboembolism (PTE). Deep vein thrombosis is the main source of thrombosis causing pulmonary thromboembolism, which causes embolism by circulating to the pulmonary artery. Blood stasis, increased blood coagulability, and venous endothelial damage are promoting factors for thrombosis. Therefore, trauma, long-term bed rest, varicose veins, venous intubation, pelvic and hip surgery, obesity, diabetes, contraceptive drugs or other causes of hypercoagulability, etc. are prone to induce venous thrombosis. The risk of pulmonary embolism is highest in the first few days of thrombosis.

[0004] Pulmonary embolism is one of the three common lethal cardiovascular diseases, with high incidence, high disability rate and high mortality, and is a severe and acute condition of the respiratory system. Acute pulmonary embolism is an acute development of pulmonary circulation disorders, and common symptoms include dyspnea, chest pain, hemoptysis, syncope, and even death. The main method for treating pulmonary embolism is surgical treatment, which is performed in a timely manner after the onset to avoid recurrence and cause death in patients.

[0005] The traditional surgical method for treating pulmonary embolism mainly includes the following methods:

[0006] 1. Thrombolytic therapy

[0007] Dissolving the thrombus in the pulmonary artery rapidly reduces the pulmonary artery pressure, improves the right heart function, reduces or eliminates the impact on left ventricular diastolic function, improves left heart function and cardiogenic shock, improves pulmonary perfusion, prevents chronic pulmonary hypertension and long-term prognosis, and dissolves deep vein thrombosis to prevent repeated embolism.

[0008] 2. Anticoagulant therapy

[0009] Prevent the development and formation of new thrombi. Simple anticoagulation is not ideal in some high-risk and medium-risk PE patients. Many doctors try to improve the efficacy by systemic thrombolysis, direct catheter thrombolysis, or surgical thrombectomy.

[0010] 3. Thrombus fragmentation and aspiration through a venous catheter

[0011] It is mainly used for massive PTE in the main stem or main branch of pulmonary artery, and the following conditions: thrombolysis and anticoagulant therapy contraindication; thrombolysis or active medical treatment failure; lack of surgical conditions, etc.

[0012] 4. Implantation of inferior vena cava filter

[0013] It is mainly used for the following conditions: repeated PTE after sufficient anticoagulation; massive PTE with hemodynamic changes; proximal massive thrombus before thrombolysis; chronic recurrent PTE with pulmonary hypertension; pulmonary thrombectomy or pulmonary thromboendarterectomy.

[0014] 5. Pulmonary thrombectomy

[0015] Surgical thrombectomy, pulmonary endarterectomy, traditional surgical method with large trauma.

[0016] The current interventional treatment for acute pulmonary embolism mainly includes catheter thrombolysis and catheter-based thrombus removal / resection.

[0017] Interventional therapy using thrombectomy devices has become an effective and important treatment method for acute pulmonary embolism. However, the existing thrombectomy devices have the problem of thrombus escaping, resulting in a lower amount of thrombus removed at a time. In addition, the existing thrombectomy devices also have room for improvement in terms of convenient delivery or convenient sheathing and un-sheathing. SUMMARY

[0018] Therefore, it is necessary to provide a thrombectomy device that facilitates increasing the amount of thrombus removed at a time and is convenient to deliver, or a thrombectomy device that facilitates increasing the amount of thrombus removed at a time and is convenient to sheath and un-sheath.

[0019] A thrombectomy device includes a thrombectomy stent, the thrombectomy stent including an interception net and a plurality of interception members spaced apart along the circumference of the interception net and arranged on the interception net, a proximal end of each of the interception members being connected to the interception net, and a distal end being a free end.

[0020] In a natural state, the plurality of interception members are located outside the interception net, and each of the interception members is folded outward from the end connected to the interception net, and in a stretched state, the folded outward part can be folded distally.

[0021] Alternatively, in a natural state, the plurality of interception members are located inside the interception net, and in a stretched state, the plurality of interception members do not cross in the radial direction.

[0022] In one embodiment, the interception net comprises a first expanded portion, the first expanded portion comprises a plurality of first mesh units, the plurality of first mesh units are connected to form a circumferentially closed mesh structure, the interception members are arranged on the first mesh units, in a natural state, the plurality of interception members are located outside the interception net, and the interception members are folded outward from one end connected to the first mesh units, in a stretched state, the outward folded part can be folded distally, and the length of the interception member after the outward folded part is folded distally is less than the length of the first mesh unit.

[0023] In one embodiment, the interception net comprises a first expanded portion, the first expanded portion comprises a plurality of first mesh units, the plurality of first mesh units are connected to form a circumferentially closed mesh structure, the interception members are arranged on the first mesh units, each of the interception members comprises two interception rods, the two interception rods are connected to form a distal closed end, one end of the two interception rods away from the distal closed end is connected to the first mesh unit, and the distal closed end is a free end; or, the interception member comprises two first interception rods and a second interception rod, two ends of the second interception rod are connected to one end of the two first interception rods, and one end of the first interception rod away from the second interception rod is connected to the first mesh unit.

[0024] In one embodiment, each of the first mesh units comprises two first proximal rods, two first intermediate rods and two first distal rods, the two first proximal rods are connected at a proximal end, the two first distal rods are connected at a distal end, proximal ends of the two first intermediate rods are connected to distal ends of the two first proximal rods respectively, distal ends of the two first intermediate rods are connected to proximal ends of the two first distal rods respectively, and adjacent two first mesh units share one first intermediate rod.

[0025] In one embodiment, the hardness of the interception members is less than the hardness of the first proximal rods, the first intermediate rods and the first distal rods.

[0026] In one embodiment, the rod diameter of the interception members is less than the rod diameter of the first proximal rods, the first intermediate rods and the first distal rods.

[0027] In one embodiment, a filter membrane is arranged on the interception net, a proximal end of the filter membrane is open, and a proximal edge of the filter membrane has a wave-shaped structure with a plurality of convex portions, and adjacent two convex portions have a gap therebetween.

[0028] In one of the embodiments, the thrombus extraction device further comprises a filter membrane fixing member, the filter membrane fixing member comprises a proximal end fixing part and a distal end fixing part connected with the proximal end fixing part, the proximal end fixing part is in a cylindrical shape, the distal end fixing part is in a truncated cone shape, the distal end fixing part extends out of the intercepting net, the proximal end fixing part is connected with the intercepting net, and the distal end of the filter membrane is clamped between the proximal end fixing part and the intercepting net.

[0029] In one of the embodiments, the gap between the two adjacent protruding parts is located in the first mesh unit.

[0030] In one of the embodiments, the intercepting net is a first intercepting part, the thrombus extraction device further comprises a second intercepting part connected with the distal end of the first intercepting part, and the first intercepting part and the second intercepting part are connected through a flexible connecting member.

[0031] The thrombus extraction device comprises a thrombus extraction stent, the thrombus extraction stent comprises an intercepting net and a plurality of intercepting members arranged on the intercepting net in a circumferential direction.

[0032] When in a natural state, the plurality of intercepting members are located outside the intercepting net, and each intercepting member is folded outward from one end connected with the intercepting net, thereby improving the proximal end interception capability in the circumferential direction, which is conducive to intercepting more thrombus. And in a stretched state, the outward folded part can be folded towards the distal end, thereby enabling the thrombus extraction device to be delivered with a smaller delivery profile, facilitating delivery.

[0033] When in a natural state, the plurality of intercepting members are located inside the intercepting net, thereby improving the proximal end interception capability in the circumferential direction, which is conducive to intercepting more thrombus. And in a stretched state, when the plurality of intercepting members do not cross in the radial direction, it is convenient to enter and exit the sheath. BRIEF DESCRIPTION OF DRAWINGS

[0034] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0035] In which:

[0036] Figure 1 It is a structural schematic diagram of the thrombus extraction device of an embodiment;

[0037] Figure 2 It is a structural schematic diagram of the thrombus extraction stent of an embodiment;

[0038] Figure 3 It is a structural schematic diagram of the proximal end of the thrombus extraction stent of an embodiment;

[0039] Figure 4 Structure diagram of the first intercepting part of the stent for one embodiment;

[0040] Figure 5 Structure diagram of the connection between the intercepting part and the first mesh unit of the stent for one embodiment;

[0041] Figure 6 Structure diagram of the stent for one embodiment;

[0042] Figure 7 Structure diagram of the stent for another embodiment;

[0043] Figure 8 Structure diagram of the stent for another embodiment; Figure 4 Enlarged view of the stent for another embodiment;

[0044] Figure 9 Structure diagram of the second intercepting part of the stent for one embodiment;

[0045] Figure 10 Structure diagram of the second intercepting part from another angle for one embodiment;

[0046] Figure 11 Enlarged view of the stent for another embodiment; Figure 9 Structure diagram of the stent for another embodiment from another angle;

[0047] Figure 12 Structure diagram of the stent for another embodiment omitting the third intercepting part;

[0048] Figure 13 Structure diagram of the stent for another embodiment omitting the third intercepting part;

[0049] Figure 14 Structure diagram of the intercepting part for another embodiment;

[0050] Figure 15 Structure diagram of the stent for another embodiment;

[0051] Figure 16 Structure diagram of the stent for another embodiment;

[0052] Figure 17 Structure diagram of the stent for another embodiment from another angle; Figure 16 Structure diagram of the stent for another embodiment from another angle;

[0053] Figure 18 Structure diagram of the stent for another embodiment;

[0054] Figure 19 Structure diagram of the stent for another embodiment from another angle; Figure 18 Structure diagram of the stent for another embodiment from another angle;

[0055] Figure 20 Structure diagram of a stent for another embodiment;

[0056] Figure 21 Structure diagram of a stent for another embodiment;

[0057] Figure 22 Structure diagram of a stent for another embodiment;

[0058] Figure 23 Structure diagram of a stent for another embodiment;

[0059] Figure 24 Structure diagram of a stent for another embodiment;

[0060] Figure 25 Structure diagram of a stent for another embodiment;

[0061] Figure 26 Structure diagram of a filter membrane in an open state for an embodiment;

[0062] Figure 27 Structure diagram of a filter membrane fixing member for an embodiment;

[0063] Figure 28 Structure diagram of a filter membrane fixing member for an embodiment; Figure 27 Structure diagram of a filter membrane fixing member for an embodiment;

[0064] Figure 29 Structure diagram of a stent for another embodiment;

[0065] Figure 30 Structure diagram of a stent for another embodiment.

[0066] Reference numerals:

[0067] 1. A thrombectomy device;

[0068] 10. A stent;

[0069] 110. A first intercepting portion; 110a, a proximal end; 110b, a distal end; 111, a first expanding portion; 1111, a first mesh cell; 1111A, a first proximal end rod; 1111B, a first intermediate rod; 1111C, a first distal end rod; 1111a, a first proximal end connecting end; 1111c, a first distal end connecting end; 112, a first proximal end connecting portion; 1121, a first proximal end connecting rod; 1121A, a connecting portion; 1121B, a transition portion; 113, a first distal end connecting portion; 1131, a first distal end connecting rod; 1131A, a first straight rod segment; 1131B, a first branched rod segment;

[0070] 120, second intercepting part; 120a, proximal end; 120b, distal end; 121, second expanding part; 1211, second mesh unit; 1211A, second proximal end rod; 1211B, second intermediate rod; 1211C, second distal end rod; 1211a, second proximal end connecting end; 1211c, second distal end connecting end; 122, second proximal end connecting part; 1221, second proximal end connecting rod; 1221A, second straight rod segment; 1221B, second branch rod segment; 123, second distal end connecting part; 1231, second distal end connecting rod; 1231A, third straight rod segment; 1231B, third branch rod segment;

[0071] 130, third intercepting part; 131, intercepting piece; 1311, intercepting rod; 1312, first intercepting rod; 1313, second intercepting rod; 1314, free end;

[0072] 140, first converging piece; 150, second converging piece; 160, third converging piece;

[0073] 20, filter membrane; 30, filter membrane fixing piece; 40, pushing rod. DETAILED DESCRIPTION

[0074] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0075] In the description of the embodiments of the present application, it should be noted that the orientations or positional relationships indicated by terms such as “center”, “upper”, “lower”, “left”, “right”, “vertical”, “horizontal”, “inner”, “outer” and the like are based on the orientations or positional relationships shown in the drawings, and are only for the convenience of describing the embodiments of the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the embodiments of the present application. In addition, the terms “first”, “second”, “third” are only for the purpose of description, and cannot be understood as indicating or implying relative importance.

[0076] In the description of the embodiments of the present application, it should be noted that unless specifically defined and limited, the terms "mounting", "connecting", "connecting" should be understood in a broad sense, for example, it can be fixedly connected, or it can be replaceably connected, or it can be integrally connected, it can be mechanically connected, or it can be electrically connected, it can be directly connected, or it can be indirectly connected through an intermediate medium, it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the embodiments of the present application can be understood according to the specific circumstances.

[0077] In the field of interventional medical devices, the end of a medical device implanted in the human or animal body closer to the operator is generally referred to as the "proximal end", and the end farther away from the operator is referred to as the "distal end", and the "proximal end" and "distal end" of any component of the medical device are defined according to this principle. The "axial direction" generally refers to the length direction of the medical device when it is being delivered, and the "radial direction" generally refers to the direction perpendicular to the "axial direction" of the medical device, and the "axial direction" and "radial direction" of any component of the medical device are defined according to this principle.

[0078] Please refer to Figure 1 The thrombus extraction device 1 of an embodiment includes a thrombus extraction stent 10. Please refer to Figure 2 The thrombus extraction stent 10 includes a first intercepting portion 110, a second intercepting portion 120, and a third intercepting portion 130. The first intercepting portion 110 has a proximal end 110a and a distal end 110b, the second intercepting portion 120 has a proximal end 120a and a distal end 120b, and the proximal end 120a of the second intercepting portion 120 is connected to the distal end 110b of the first intercepting portion 110. Please refer to Figure 3 (only part of the intercepting pieces 131 are marked), the third intercepting portion 130 includes a plurality of intercepting pieces 131, and the plurality of intercepting pieces 131 are arranged on the first intercepting portion 110 along the circumferential direction of the first intercepting portion 110.

[0079] In the above-mentioned thrombus extraction device 1, the proximal end 120a of the second intercepting portion 120 of the thrombus extraction stent 10 is connected to the distal end 110b of the first intercepting portion 110, forming two levels of interception in the axial direction; the plurality of intercepting pieces 131 of the third intercepting portion 130 are arranged on the first intercepting portion 110 along the circumferential direction of the first intercepting portion 110, thereby improving the interception capability of the proximal end in the circumferential direction, which is conducive to intercepting more thrombus. Thus, it is conducive to improving the single thrombus extraction amount.

[0080] Please refer to Figure 4In an embodiment, the first intercepting portion 110 comprises a first expanding portion 111, each intercepting member 131 extends from the proximal end of the first expanding portion 111 to the distal end, and the distal end of the intercepting member 131 is a free end. In a natural state, the plurality of intercepting members 131 are located outside the first expanding portion 111, so that the radial size of the third intercepting portion 130 is greater than the radial size of the first intercepting portion 110, which is conducive to intercepting thrombus. Moreover, the distal end of the intercepting member 131 is a free end, so that when the shaft is axially stretched for delivery, the intercepting member 131 can freely extend, which is conducive to reducing the delivery profile.

[0081] The first expanding portion 111 comprises a plurality of first grid units 1111, and the plurality of first grid units 1111 are connected to form a circumferentially closed grid structure.

[0082] Please refer to Figure 4 and Figure 5 In an embodiment, the first grid unit 1111 comprises two first proximal rods 1111A, two first intermediate rods 1111B, and two first distal rods 1111C. The two first proximal rods 1111A are connected to form a first proximal connecting end 1111a at the proximal end. The two first distal rods 1111C are connected to form a first distal connecting end 1111c at the distal end. One end of each of the two first intermediate rods 1111B is connected to one end of each of the two first proximal rods 1111A away from the first proximal connecting end 1111a, and the other end is connected to one end of each of the two first distal rods 1111C away from the first distal connecting end 1111c. The two first proximal rods 1111A, the two first intermediate rods 1111B, and the two first distal rods 1111C form a frame structure. Each first grid unit 1111 shares one first intermediate rod 1111B with an adjacent first grid unit 1111, and the plurality of first grid units 1111 form a circumferentially closed grid structure.

[0083] Please refer to Figure 4 In an embodiment, the first intercepting portion 110 further comprises a first proximal connecting portion 112 and a first distal connecting portion 113, and the two ends of the first expanding portion 111 are connected to the first proximal connecting portion 112 and the first distal connecting portion 113 respectively, forming a grid structure with small ends and a large middle. That is, the first proximal connecting portion 112 converges towards the proximal end from the end connected to the first expanding portion 111, and the first distal connecting portion 113 converges towards the distal end from the end connected to the first expanding portion 111.

[0084] The first proximal connecting portion 112 converges towards the proximal end from the end connected to the first expanding portion 111, which is conducive to pulling the thrombus removal device 1 and the intercepted thrombus into the sheath tube together during the thrombus removal process, so as to remove the thrombus. The first distal connecting portion 113 converges towards the distal end from the end connected to the first expanding portion 111, which is conducive to improving the flexibility of the middle part of the thrombus removal device 1.

[0085] Please refer to Figure 4 and Figure 6 In an embodiment, the first proximal connecting part 112 comprises a plurality of first proximal connecting rods 1121. One end of each of the first proximal connecting rods 1121 is connected to the first proximal connecting end 1111a of the first expansion part 111, and the other ends of all the first proximal connecting rods 1121 converge in the first converging member 140.

[0086] In an embodiment, the first proximal connecting rods 1121 are strip-shaped rods, and the number of the first proximal connecting rods 1121 is equal to the number of the first mesh units 1111. In this way, on the one hand, the first proximal connecting part 112 can better support the first expansion part 111, which is conducive to keeping the first expansion part 111 in a radially expanded state and avoiding the first interception part 110 collapsing to cause thrombus escape. On the other hand, in the process of withdrawing the thrombus-removing stent 10 to bring the thrombus into the sheath tube, the first proximal connecting part 112 directly contacts the thrombus. The greater the density of the first proximal connecting part 112, the more thrombus it can intercept, and the higher the single thrombus-removing amount.

[0087] Please refer to Figure 7 In another embodiment, the first proximal connecting rod 1121 comprises a connecting part 1121A and a transition part 1121B connected to the connecting part 1121A. One end of the connecting part 1121A away from the transition part 1121B is connected to the first converging member 140, and one end of the transition part 1121B away from the connecting part 1121A is connected to the first expansion part 111. The width of the transition part 1121B gradually decreases from one end close to the first expansion part 111 to one end away from the first expansion part 111, so that the first proximal connecting rod 1121 can better support the first expansion part 111.

[0088] Please refer to Figure 4 In an embodiment, the first proximal connecting part 112 comprises a plurality of first proximal connecting rods 1121. One end of each of the first proximal connecting rods 1121 is connected to the first proximal connecting end 1111a of the first expansion part 111, and the other ends of all the first proximal connecting rods 1121 converge in the first converging member 140.

[0089] Please refer to Figure 4 and Figure 8In an embodiment, the first distal connecting rod 1131 is a Y-shaped rod, including a first straight rod segment 1131A and two first branch rod segments 1131B connected to one end of the first straight rod segment 1131A. The other end of the first straight rod segment 1131A, away from the first branch rod segments 1131B, is connected to the second converging member 150, and the other ends of the two first branch rod segments 1131B, away from the first straight rod segment 1131A, are respectively connected to the two first distal connecting ends 1111c of the two adjacent first grid units 1111.

[0090] Please refer to FIG. 9. In an embodiment, the second intercepting portion 120 includes a second expanding portion 121, a second proximal connecting portion 122, and a second distal connecting portion 123. The two ends of the second expanding portion 121 are respectively connected to the second proximal connecting portion 122 and the second distal connecting portion 123, forming a grid structure with small ends and a large middle.

[0091] The second expanding portion 121 includes a plurality of second grid units 1211, which are connected to form a circumferentially closed grid structure.

[0092] In an embodiment, the second grid unit 1211 includes two second proximal rods 1211A, two second intermediate rods 1211B, and two second distal rods 1211C. The two second proximal rods 1211A are connected to form a second proximal connecting end 1211a at the proximal end, the two second distal rods 1211C are connected to form a second distal connecting end 1211c at the distal end, and one end of each of the two second intermediate rods 1211B is connected to the end of the second proximal rod 1211A away from the second proximal connecting end 1211a, and the other end is connected to the end of the second distal rod 1211C away from the second distal connecting end 1211c. The two second proximal rods 1211A, the two second intermediate rods 1211B, and the two second distal rods 1211C form a frame structure. Each second grid unit 1211 shares one second intermediate rod 1211B with an adjacent second grid unit 1211, and a plurality of second grid units 1211 form a circumferentially closed grid structure.

[0093] Please continue to refer to Figure 9 In an embodiment, the second proximal connecting portion 122 includes a plurality of second proximal connecting rods 1221. One end of each second proximal connecting rod 1221 is connected to the second proximal connecting end 1211a of the second expanding portion 121, and the other ends of all second proximal connecting rods 1221 converge in the second converging member 150.

[0094] Please refer to FIG. 9. Figure 9 and Figure 10In an embodiment, the second proximal connecting rod 1221 is a Y-shaped rod, comprising a second straight rod segment 1221A and two second branch rod segments 1221B connected to one end of the second straight rod segment 1221A. The other end of the second straight rod segment 1221A away from the second branch rod segments 1221B is connected to the second converging member 150, and the other ends of the two second branch rod segments 1221B away from the second straight rod segment 1221A are respectively connected to the two second proximal connecting ends 1211a of the two second mesh units 1211 connected thereto.

[0095] Please refer back to Figure 9 In an embodiment, the second distal connecting part 123 comprises a plurality of second distal connecting rods 1231. One end of each second distal connecting rod 1231 is connected to the second distal connecting end 1211c of the second expanding part 121, and the other ends of all the second distal connecting rods 1231 converge in the third converging member 160.

[0096] Please refer back to Figure 9 and Figure 11 In an embodiment, the second distal connecting rod 1231 is a Y-shaped rod, comprising a third straight rod segment 1231A and two third branch rod segments 1231B connected to one end of the third straight rod segment 1231A. The other end of the third straight rod segment 1231A away from the third branch rod segments 1231B is connected to the third converging member 160, and the other ends of the two third branch rod segments 1231B away from the third straight rod segment 1231A are respectively connected to the two second distal connecting ends 1211c of the two second mesh units 1211 adjacent thereto.

[0097] The plurality of first distal connecting rods 1131 of the first intercepting part 110 and the plurality of second proximal connecting rods 1221 of the second intercepting part 120 converge in the second converging member 150. Please refer back to Figure 7 In an embodiment, the plurality of first distal connecting rods 1131 and the plurality of second proximal connecting rods 1221 are staggered in the radial direction of the second converging member 150, on the one hand making the overall flexibility of the stent 10 smaller, and on the other hand making the plurality of first distal connecting rods 1131 and the plurality of second proximal connecting rods 1221 cooperate with each other to increase the intercepting area, which is beneficial to intercept more thrombus.

[0098] In an embodiment, the first distal connecting rod 1131 is a Y-shaped rod, one end of the first straight rod segment 1131A of the first distal connecting rod 1131 away from the first branch rod segment 1131B is connected with the second converging member 150, and the two ends of the two first branch rod segments 1131B away from the first straight rod segment 1131A are connected with two adjacent first grid units 1111 of the first expanding part 111. And the second proximal connecting rod 1221 is a Y-shaped rod, one end of the second straight rod segment 1221A of the second proximal connecting rod 1221 away from the second branch rod segment 1221B is connected with the second converging member 150, and the two ends of the two second branch rod segments 1221B away from the second straight rod segment 1221A are connected with two adjacent second grid units 1211 of the second expanding part 121. That is, the area of the part where the first distal connecting rod 1131 and the second proximal connecting rod 1221 are connected with the second converging member 150 is small, so that the area of the connection part of the first intercepting part 110 and the second intercepting part 120 with the second converging member 150 is small, which is beneficial to improve the flexibility of the whole thrombus extraction stent 10. Further, the first distal connecting rod 1131 and the second distal connecting rod 1221 are staggered in the radial direction of the second converging member 150, so that the middle part of the thrombus extraction stent 10 has good flexibility. At the same time, the radial staggering is beneficial to improve the interception performance while ensuring flexibility. And the two first branch rod segments 1131B can better support the first expanding part 111, and the two second branch rod segments 1221B can better support the second expanding part 121, so that the first intercepting part 110 and the second intercepting part 120 can better maintain the state of radial expansion to better intercept thrombus and avoid thrombus escape, thereby improving the single thrombus extraction amount.

[0099] The second converging member 150 has a ring structure. Please continue to refer to Figure 7 In an embodiment, the part of the second converging member 150 between the two adjacent first distal connecting rods 1131 is concave, and the part of the second converging member 150 between the two adjacent second proximal connecting rods 1221 is concave, so that the flexibility of the second converging member 150 is smaller.

[0100] The first intercepting part 110 and the second intercepting part 120 are connected in the axial direction. During thrombus extraction, the first intercepting part 110 is located at the proximal end, and the second intercepting part 120 is located at the distal end. The thrombus is intercepted by the first intercepting part 110, and when small thrombus is generated and escapes from the first intercepting part 110, the second intercepting part 120 can intercept the small thrombus. Thus, it is beneficial to capture the escaped thrombus and improve the single thrombus extraction amount.

[0101] It should be noted that in other embodiments, the first intercepting part 110 and the second intercepting part 120 are not limited to the structure described above, but can also be other structures. For example Figure 12As shown, in another embodiment, the first intercepting part 110 comprises a first expanding part 111, a first proximal end connecting part 112 and a first distal end connecting part 113, and the two ends of the first expanding part 110 are connected with the first proximal end connecting part 112 and the first distal end connecting part 113 respectively.

[0102] The structure of the first expanding part 111 is the same as that of the first expanding part 111 of the embodiment shown in the figure, which will not be described here again. Figure 4 The structure of the first expanding part 111 is the same as that of the first expanding part 111 of the embodiment shown in the figure, which will not be described here again.

[0103] The first proximal end connecting part 112 comprises a plurality of first proximal end connecting rods 1121, and the first distal end connecting part 113 comprises a plurality of first distal end connecting rods 1131. The first proximal end connecting rods 1121 and the first distal end connecting rods 1131 are straight rods. The number of the first proximal end connecting rods 1121 is equal to the number of the first grid units 1111 of the first expanding part 111, and the number of the first distal end connecting rods 1131 is equal to the number of the first grid units 1111 of the first expanding part 111. One end of each first proximal end connecting rod 1121 is connected with the first proximal end connecting end 1111a of the first expanding part 111, and the other end is connected with the first converging piece 140. One end of each first distal end connecting rod 1131 is connected with the first distal end connecting end 1111c of the first expanding part 111, and the other end is connected with the second converging piece 150, thereby forming a structure with large middle and small both ends.

[0104] The second intercepting part 120 comprises a second expanding part 121, a second proximal end connecting part 122 and a second distal end connecting part 123, and the two ends of the second expanding part 121 are connected with the second proximal end connecting part 122 and the second distal end connecting part 123 respectively.

[0105] The structure of the second expanding part 121 is the same as that of the second expanding part 121 of the embodiment shown in the figure, which will not be described here again. Figure 9 The structure of the second expanding part 121 is the same as that of the second expanding part 121 of the embodiment shown in the figure, which will not be described here again.

[0106] The second proximal end connecting part 122 comprises a plurality of second proximal end connecting rods 1221, and the second distal end connecting part 123 comprises a plurality of second distal end connecting rods 1231. The second proximal end connecting rods 1221 and the second distal end connecting rods 1231 are straight rods. The number of the second proximal end connecting rods 1221 is equal to the number of the second grid units 1211 of the second expanding part 121, and the number of the second distal end connecting rods 1231 is equal to the number of the second grid units 1211 of the second expanding part 121. One end of each second proximal end connecting rod 1221 is connected with the second proximal end connecting end 1211a of the second expanding part 121, and the other end is connected with the second converging piece 150. One end of each second distal end connecting rod 1231 is connected with the second distal end connecting end 1211c of the second expanding part 121, and the other end is connected with the third converging piece 160, thereby forming a structure with small proximal end, large middle and tapered distal end.

[0107] Figure 12 In the illustrated embodiment, different from the first intercepting portion 110, the length of the second distal connecting rod 1231 of the second intercepting portion 120 is relatively large, and the ends of all the second distal connecting rods 1231 away from the second expansion portion 121 converge at the third converging member 160, thereby forming a distal tapered structure. In this way, the second intercepting portion 120 has a relatively large volume and can intercept more thrombus, which is conducive to improving the single thrombus removal amount.

[0108] Please refer to Figure 13 In another embodiment, the first intercepting portion 110 and the second intercepting portion 120 are both tapered at one end. The difference is that the tapered portion of the first intercepting portion 110 is located at the proximal end, and the tapered portion of the second intercepting portion 120 is located at the distal end. The proximal end of the first intercepting portion 110 is tapered, which is conducive to the interception of thrombus and the retraction of the thrombus and the thrombus removal stent 10 into the catheter. The distal end of the second intercepting portion 120 is tapered, so that the second intercepting portion 120 has a relatively large volume and can intercept more thrombus, which is conducive to improving the single thrombus removal amount.

[0109] It should be noted that in other embodiments, regardless of the structure of the first proximal connecting rod 1121 and the second distal connecting rod 1231, the first proximal connecting rod 1121 and / or the second distal connecting rod 1231 with a relatively large length can be selected, so that the proximal end of the first intercepting portion 110 is tapered and / or the distal end of the second intercepting portion 120 is tapered, to facilitate the retraction of the thrombus removal stent 10 into the sheath and / or increase the intraluminal volume of the second intercepting portion 120 to intercept more thrombus.

[0110] Please refer to Figure 3 and Figure 5 In an embodiment, in a natural state, the plurality of intercepting members 131 are located outside the first intercepting portion 110, and the radial dimension of the third intercepting portion 130 is greater than the radial dimension of the first intercepting portion 110, so that when the thrombus removal stent 10 is implanted in the blood vessel, the third intercepting portion 130 can be in contact with the blood vessel wall to effectively intercept the thrombus, and the third intercepting portion 130 is conducive to scraping and intercepting the thrombus adhering to the wall, thereby improving the single thrombus removal amount.

[0111] Here, the radial dimension of the first intercepting portion 110 can refer to the diameter of the circumscribed circle of the first intercepting portion 110. The radial dimension of the third intercepting portion 130 can refer to the diameter of the circumscribed circle of the plurality of intercepting members 131.

[0112] In an embodiment, each intercepting member 131 extends distally from one end connected to the first intercepting portion 110, and the distal end of the intercepting member 131 is a free end, so that in the stretched state, the thrombus removal stent 10 has a relatively small delivery profile.

[0113] Please continue to refer to Figure 5 In an embodiment, the intercepting member 131 includes two intercepting rods 1311, and the two intercepting rods 1311 are connected to form a distal end closed end. The two ends of the two intercepting rods 131 away from the distal end closed end are connected to the two first proximal rods 1111A respectively, and the distal end closed end is a free end.

[0114] In an embodiment, the intercepting member 131 is in the shape of a leaf, and the distal end of the intercepting member 131 is a pointed structure, which is conducive to making the flexibility of the thrombectomy device 1 as a whole better.

[0115] It should be noted that in other embodiments, the intercepting member 131 is not limited to the shape of a leaf, but can be other structures. Please refer to Figure 14 In another embodiment, the intercepting member 131 includes two first intercepting rods 1312 and a second intercepting rod 1313, and the two ends of the second intercepting rod 1313 are connected to one end of the two first intercepting rods 1312 respectively. The end of the first intercepting rod 1312 away from the second intercepting rod 1313 is a free end. The free ends of the two first intercepting rods 1312 are connected to the two first proximal rods 1111A of the first mesh unit 1111, and the first intercepting rod 1312 extends axially from the proximal end to the proximal end. The second intercepting rod 1313 extends substantially in the circumferential direction. The intercepting member 131 of this embodiment can also improve the intercepting effect and reduce the risk of thrombus escape, and the free end of the intercepting member 131 is not a pointed structure, which is conducive to avoiding damage to the blood vessel by the intercepting member 131.

[0116] Regardless of the shape of the intercepting member 131, in an embodiment, in the stretched state, the length of the intercepting member 131 is less than the length of the first mesh unit 1111. That is, in the stretched state, the intercepting member 131 extends inside the first mesh unit 1111, and the distal end closed end of the intercepting member 131 will not lap on any one of the first proximal rod 1111A, the first intermediate rod 1111B and the second distal rod 1111C. Therefore, the third intercepting part 130 is provided, which will not significantly increase the delivery profile of the thrombectomy device 1, nor will it significantly increase the stiffness of the thrombectomy device 1.

[0117] In an embodiment, the stiffness of the intercepting part 130 is less than the stiffness of the first expanding part 111. Specifically, the stiffness of the intercepting rod 1311, the first intercepting rod 1312 and the second intercepting rod 1313 is less than the stiffness of any one of the first proximal rod 1111A, the first intermediate rod 1111B and the second distal rod 1111C. The provision of the intercepting part 130 with smaller stiffness is conducive to avoiding the stimulation of the blood vessel wall by the intercepting part 130, and making the flexibility of the thrombectomy device 1 better.

[0118] In an embodiment, the diameters of the bars of the intercepting rod 1311, the first intercepting rod 1312 and the second intercepting rod 1313 are all smaller than the diameters of the first proximal rod 1111A, the first intermediate rod 1111B and the second distal rod 1111C, so that the hardness of the intercepting portion 130 is smaller than the hardness of the first expanding portion 111.

[0119] In an embodiment, the plurality of intercepting members 131 correspond to the plurality of first mesh units 1111 one by one, that is, one intercepting member 131 is connected to one first mesh unit 1111.

[0120] It should be noted that in other embodiments, when the number of the first mesh units 1111 is large, the intercepting members 131 can be arranged at intervals of one first mesh unit 1111, that is, the number of the first mesh units 1111 is twice the number of the intercepting members 131, so as to ensure certain intercepting ability, flexibility and smaller conveying profile.

[0121] Please refer to Figure 15 In an embodiment, the plurality of intercepting members 131 are located outside the first intercepting portion 110. The plane in which the two first intermediate rods 1111B of the first mesh unit 1111 defining the first expanding portion 111 are located is defined as plane A (not shown in the figure), and the angle between each intercepting member 131 and the plane A of the first mesh unit 1111 in which it is located is 0°-45°.

[0122] When the angle between the intercepting member 131 and the plane A of the first mesh unit 1111 in which it is located is 0°, the intercepting member 131 is parallel to the longitudinal central axis B-B of the thrombus capturing stent 10, which is conducive to avoiding the free end of the intercepting member 131 from tilting outward and stimulating the blood vessel wall when implanted in the blood vessel, thereby avoiding blood vessel damage.

[0123] When the angle between the intercepting member 131 and the plane A of the first mesh unit 1111 in which it is located is greater than 0°, the intercepting member 131 expands outward relative to the first mesh unit 1111, which is conducive to intercepting thrombus. At the same time, limiting the angle between the intercepting member 131 and the plane A of the first mesh unit 1111 in which it is located to be within 45° is conducive to reducing the stimulation of the blood vessel wall by the free end of the intercepting member 131.

[0124] In an embodiment, the angle between each intercepting member 131 and the plane A of the first mesh unit 1111 in which it is located is 0°-45°, and the hardness of the intercepting member 131 is small, so as to reduce the stimulation of the blood vessel wall while being able to intercept more thrombus. The ways to achieve small hardness of the intercepting member 131 include but are not limited to using thinner wire material to prepare the intercepting member 131, or cutting to form an intercepting member 131 with smaller diameter or radial size, or other processing, for example, polishing to make the hardness of the intercepting member 131 smaller.

[0125] In an embodiment, each intercepting member 131 forms an angle with the plane A of the first mesh unit 1111 in which the intercepting member 131 is located, and the angle is greater than or equal to 0°, so that in the stretched state, the intercepting member 131 extends inside the first mesh unit 1111, and the plurality of intercepting members 131 do not intersect in the radial direction to avoid interference when pulling the stent 10 back into the sheath during the stent retrieval process.

[0126] Please refer to Figure 16 and Figure 17 In an embodiment, in the natural state, the intercepting member 131 is folded outward from one end connected to the first mesh unit 1111, so that the free end 1314 of the intercepting member 131 is directed towards the first constriction member 140, which is beneficial to avoid damaging the blood vessel wall. Furthermore, the end of the intercepting member 131 away from the first mesh unit 1111 is a free end, so that in the stretched state, the everted portion can be folded distally to enable delivery with a smaller delivery profile. Further, in the stretched state, the length of the intercepting member 131 after the everted portion is folded distally is less than the length of the first mesh unit 1111, i.e., the intercepting member 131 extends within the first mesh unit 1111 in the stretched state to reduce the delivery profile and improve flexibility.

[0127] The first intercepting portion 110 of the stent 10 described above includes a first expansion portion 111 and a first proximal connecting portion 112 and a second proximal connecting portion 113 connected to both ends of the first expansion portion 111, respectively. The first mesh unit 1111 of the first expansion portion 111 is a frame structure including a first proximal rod 1111A, a first intermediate rod 1111B, and a first distal rod 1111C. On the one hand, the first mesh unit 1111 of the frame structure is configured such that the first mesh unit 1111 can cooperate with the intercepting member 131, and in the stretched state, the intercepting member 131 can extend in the first mesh unit 1111 when the third intercepting portion 130 is located outside the first intercepting portion 110, which is beneficial to reduce the delivery profile and improve flexibility. In the natural state and the released state, at least part of the intercepting member 131 is opposite to the area enclosed by the first mesh unit 1111, which is beneficial to improve the interception capability of the stent 10, thereby improving the single stent retrieval amount. Therefore, by using the above connection mode of the first intercepting portion 110 to set the third intercepting portion 130, compared with simply increasing the weaving density of the stent or increasing the density of the support rods of the stent to improve the interception performance, the flexibility of the delivery and the interception performance can be ensured.

[0128] Please refer to Figure 18 and Figure 19In an embodiment, in the natural state, the third interception portion 130 is located inside the first interception portion 110. That is, each of the interception members 131 is located inside the first interception portion 110. And, each of the interception members 131 is connected with two first intermediate rods 1111B of the corresponding first mesh unit 1111. The third interception portion 130 located inside the first interception portion 110 can improve the proximal interception capability in the circumferential direction, which is conducive to intercepting more thrombus. Thus, it is conducive to improving the single thrombus extraction amount. And, the third interception portion 130 located inside the first interception portion 110 is conducive to avoiding the free end of the interception member 131 stimulating the blood vessel wall, while being conducive to reducing the delivery profile of the thrombus extraction stent 10.

[0129] In an embodiment, in the stretched state, the interception member 131 extends inside the first mesh unit 1111, and the plurality of interception members 131 do not intersect in the radial direction, so as to avoid interference when the thrombus extraction stent 10 is pulled back into the sheath tube during the thrombus extraction process.

[0130] When the third interception portion 130 is arranged inside the first interception portion 110, the plurality of interception members 131 can not intersect in the radial direction in the stretched state by controlling the length of the interception member 131, reasonably arranging the shape of the interception member 131, and the like. For example, the interception member 131 shown in Figure 14 is used. For another example, a shorter interception member 131 is used.

[0131] In an embodiment, the thrombus extraction stent 10 is made of a metal material. For example, the thrombus extraction stent 10 is made of a metal material such as nickel-titanium alloy, stainless steel, and the like.

[0132] In an embodiment, the first interception portion 110, the second interception portion 120, the third interception portion 130, the first converging member 140, the second converging member 150, and the third converging member 160 are integrally formed. For example, they are formed by cutting a metal tube and then shaping.

[0133] Please refer to Figure 20 In an embodiment, the thrombus extraction stent 10 includes the first interception portion 110, the second interception portion 120, the third interception portion 130, and the fourth interception portion 140. The distal end of the first interception portion 110 is connected with the proximal end of the second interception portion 120. The third interception portion 130 includes a plurality of interception members 131. The plurality of interception members 131 are arranged on the first interception portion 110 along the circumferential direction of the first interception portion 110. The fourth interception portion 140 includes a plurality of interception elements 141. The plurality of interception elements 141 are arranged on the second interception portion 120 along the circumferential direction of the second interception portion 120. In an embodiment, the interception member 131 shown in Figure 20 and the interception member 131 shown in Figure 5 have the same structure. The interception element 141 has the same structure as the interception member 131.

[0134] By providing a third intercepting part 130 on the first intercepting part 110 and a fourth intercepting part 140 on the second intercepting member 120, the interception performance of the thrombectomy bracket 10 is improved, thus increasing the amount of thrombectomy performed in a single operation. Furthermore, the structural cooperation between the intercepting member 131 and the first intercepting part 110, and between the intercepting element 140 and the second intercepting part 120, offers better flexibility compared to simply increasing the braiding density or the density of the support rods of the thrombectomy bracket to improve interception performance.

[0135] Figure 20 In the illustrated embodiment, the third intercepting part 130 is disposed inside the first intercepting part 110, and the fourth intercepting part 140 is disposed inside the second intercepting part 120. In another embodiment, please refer to... Figure 21 The third intercepting part 130 is disposed outside the first intercepting part 110, and the fourth intercepting part 140 is disposed outside the second intercepting part 120. It is understood that in other embodiments, the third intercepting part 130 may be disposed inside the first intercepting part 110, and the fourth intercepting part 140 may be disposed outside the second intercepting part 120. Alternatively, the third intercepting part 130 may be disposed outside the first intercepting part 110, and the fourth intercepting part 140 may be disposed inside the second intercepting part 120.

[0136] In one embodiment, the first intercepting part 110 and the second intercepting part 120 are connected by a flexible connector, which improves the flexibility of the thrombectomy stent 10 so that it can pass through curved anatomical structures. Alternatively, the angles of the first intercepting part 110 and the second intercepting part 120 can be adjusted to accommodate the anatomical structures of different individuals.

[0137] Please see Figure 22 In one embodiment, the first intercepting part 110 and the second intercepting part 120 are connected by a flexible connector 170. The flexible connector 170 is a hollow metal tube with a spiral groove, which is formed by cutting the metal tube to form the spiral groove.

[0138] In one embodiment, the first intercepting part 110, the second intercepting part 120, the third intercepting part 130, the first gathering member 140, the third gathering member 160 and the flexible connector 170 are integral structures formed by cutting, and the second gathering member 150 is replaced by the flexible connector 170 to improve flexibility.

[0139] Please see Figure 23 In another embodiment, the flexible connector 170 is a helical spring, the distal end of the first intercepting part 110 is converged to the first middle converging member 150A, the proximal end of the second intercepting part 120 is converged to the second middle converging member 150B, and the two ends of the helical spring are respectively connected to the first middle converging member 150A and the second middle converging member 150B.

[0140] Referring to Figure 24 In another embodiment, the flexible connecting member 170 is an elastic linear structure, which includes at least two elastic wires 171, such as nickel-titanium wires. One end of the elastic wire 171 is connected to the first intercepting portion 110, and the other end is connected to the second intercepting portion 120. In a natural state, the elastic wire 171 is in a curved structure, and when subjected to force, the elastic wire 171 can deform so that the distance or angle between the first intercepting portion 110 and the second intercepting portion 120 is adjustable.

[0141] Referring to Figure 25 In another embodiment, the flexible connecting member 170 includes a first connecting ring 171 and a second connecting ring 172, the first intercepting portion 110 is connected to the first connecting ring 171, and the second intercepting portion 120 is connected to the second connecting ring 172. The first connecting ring 171 and the second connecting ring 172 are hook-connected, and the first connecting ring 171 and the second connecting portion 172 are only hooked or overlapped, and are not fixed, so that the angle between the first intercepting portion 110 and the second intercepting portion 120 is adjustable, and the thrombus stent 10 can easily pass through the curved lumen structure.

[0142] Referring back to Figure 1 In an embodiment, a filter membrane 20 is arranged on the second intercepting portion 120, and blood flow can pass through the filter membrane 20, but thrombus cannot pass through the filter membrane, so as to intercept thrombus with smaller size and improve the single thrombus removal amount.

[0143] In an embodiment, the filter membrane 20 is accommodated in the second intercepting portion 120. In another embodiment, the filter membrane 20 is wrapped on the surface of the second intercepting portion 120.

[0144] In an embodiment, the material of the filter membrane 20 is a flexible high polymer material such as nylon or polyester, and the filter membrane 20 is connected to the second intercepting portion 120 by sewing. The filter membrane 20 is made of a flexible material, which does not significantly increase the hardness of the thrombus stent 10. On the one hand, it is not necessary to significantly increase the size of the delivery sheath, and on the other hand, it also does not significantly increase the withdrawal force of the thrombus stent 10 during thrombus removal.

[0145] In an embodiment, the filter membrane 20 is accommodated in the second intercepting portion 120. As shown in Figure 26 the filter membrane 20 is a bag-shaped structure having an axially opposite proximal end 210 and distal end 220. The distal end 220 is connected to the third constriction member 160, and the proximal end 210 is connected to the second expansion portion 121 by sewing. Among them, the proximal end 210 forms an open end, and the distal end 220 forms a closed end.

[0146] In an embodiment, the filter membrane 20 is a bag-shaped structure with a large proximal end 210 and a small distal end 220.

[0147] In an embodiment, the proximal edge of the filter membrane 20 is in a wavy structure, having a plurality of protrusions 230, and a gap 240 between two adjacent protrusions 230. The plurality of protrusions 230 are connected to the second expansion portion 121 by sutures. Generally, in order to increase the single thrombus extraction amount, and the filter membrane is made of a flexible material, the art generally tries to set a larger volume of the filter membrane, and no gap is formed at the proximal end of the filter membrane to avoid thrombus escape. The applicant unexpectedly found that the filter membrane 20 with a wavy structure at the proximal edge combined with the thrombus extraction stent 10 including the first interception portion 110, the second interception portion 120 and the third interception portion 130 can obtain a higher single thrombus extraction amount. The proximal edge of the filter membrane 20 is set to a wavy structure with a gap 240, which avoids the filter membrane at the proximal end from being squeezed together to increase the sheathing resistance during the process of pulling the thrombus into the sheath, which is beneficial to reduce the withdrawal force of the withdrawal of the thrombus extraction stent 10, so that it is easier to push the thrombus into the sheath, while avoiding the thrombus from being crushed due to large sheathing resistance to escape, thus improving the single thrombus extraction amount and safety. Compared with the structure in which the proximal end of the filter membrane 20 is set to be flush without a gap 240, the single thrombus extraction amount is higher and the safety is higher.

[0148] Please go back to Figure 1 In an embodiment, the thrombus extraction device 1 further comprises a filter membrane fixing member 30. The filter membrane fixing member 30 is used to fix the distal end of the filter membrane 20.

[0149] Please refer to Figure 27 and Figure 28 In an embodiment, the filter membrane fixing member 30 comprises a proximal end fixing portion 310 and a distal end fixing portion 320 connected to the proximal end fixing portion 310, and a through hole 330 is formed in the middle of the filter membrane fixing member 30. The through hole 330 extends along the axial direction of the filter membrane fixing member 30 and penetrates the proximal end fixing portion 310 and the distal end fixing portion 320. The through hole 330 is provided for the guide wire to pass through.

[0150] The proximal end fixing portion 310 is in a cylindrical shape, and the distal end fixing portion 320 is in a truncated conical shape. The distal end of the proximal end fixing portion 310 is connected to the larger end of the distal end fixing portion 320. The outer diameter of the proximal end fixing portion 310 is smaller than the outer diameter of the end surface of the larger end of the distal end fixing portion 320.

[0151] The third converging member 160 is a ring structure. In an embodiment, the distal end of the filter membrane 20 extends into the third converging member 160. The proximal end of the proximal fixed portion 310 of the filter membrane fixing member 30 is inserted into the third converging member 160, and the proximal end face of the distal fixed portion 320 abuts against the third converging member 160. The distal end of the filter membrane 20 is clamped by the third converging member 160 and the proximal fixed portion 310. The proximal fixed portion 310 of the filter membrane fixing member 30 is inserted into the third converging member 160, and the proximal fixed portion 310 and the third converging member 160 are fixedly connected, so that the distal end of the filter membrane fixing member 30 is fixedly connected with the thrombus extraction stent 10.

[0152] It can be understood that, in other embodiments, after the proximal fixed portion 310 of the filter membrane fixing member 30 is inserted into the third converging member 160, in addition to abutting connection, the proximal fixed portion 310 and the third converging member 160 can be further fixedly connected by bonding or welding to improve the reliability of the connection.

[0153] The distal end of the filter membrane 20 is fixed by the filter membrane fixing member 30, and the proximal end of the filter membrane 20 is sutured on the second expanding portion 121, so that when the second intercepting portion 120 is expanded, the proximal end 210 of the filter membrane 20 is in an open state to facilitate the interception of thrombus. The filter membrane fixing member 30 can support and fix the distal end of the filter membrane 20, so as to avoid the inclination of the filter membrane 20 after intercepting thrombus, thereby making it difficult to continue to effectively intercept thrombus. By providing the filter membrane fixing member 30, it is not necessary to provide a support rod penetrating the thrombus extraction stent 10 for support, so that the flexibility of the thrombus extraction device 1 is better.

[0154] In addition, the distal fixed portion 320 of the filter membrane fixing member 30 is in a truncated conical shape, and the smaller end of the bottom surface of the distal fixed portion 320 is the distal end, which is beneficial for the thrombus extraction stent 10 to pass through the thrombus and be located at the distal end of the thrombus, so as to perform the thrombus extraction operation.

[0155] It should be noted that, in other embodiments, the filter membrane 20 can be omitted, and a braided wire can be used to weave a filter mesh with a closed distal end and an open proximal end on the second intercepting portion 120.

[0156] It should be noted that, in other embodiments, the third intercepting portion 130 of the thrombus extraction stent 10 can be arranged on the second intercepting portion 120 instead of being arranged on the first intercepting portion 110.

[0157] Please refer to Figure 29, another embodiment of the thrombus extraction stent 10' includes a first interception portion 110', a second interception portion 120', and a third interception portion 130'. The first interception portion 110' and the first interception portion 110 have substantially the same structure or are the same, and the second interception portion 120' and the second interception portion 120 have substantially the same structure or are the same. The third interception portion 130' includes a plurality of interception members 131', which are arranged on the second interception portion 120' along the circumference of the second interception portion 120'.

[0158] The third interception portion 130' is arranged on the distal second interception portion 120', and the first interception portion 110' and the second interception portion 120' cooperate to improve the interception performance in the radial and axial directions.

[0159] It should be noted that when the third interception portion 130' is arranged on the distal second interception portion 120', the second interception portion 120' can be provided with a filter membrane 20 or can not be provided with a filter membrane 20. The filter membrane 20 is beneficial to further improve the interception performance.

[0160] Please refer to Figure 1 In an embodiment, the thrombus extraction device 1 further includes a pushing rod 40 connected to the first converging member 140. The pushing rod 40 is used to push the thrombus extraction stent 10 to perform thrombectomy.

[0161] Please refer to Figure 30 In another embodiment, another thrombus extraction stent 10' is provided. The thrombus extraction stent 10' includes an interception net 110' and a plurality of interception members 120' arranged on the interception net 110' along the circumference of the interception net 110'.

[0162] The structure of the interception net 110' is the same as that of the first interception portion 110, or the structure of the interception net 110' is the same as that of the second interception portion 120, and the structure and connection mode of the interception member 120' are the same as those of the interception member 131, which will not be described here.

[0163] The thrombus extraction stent 10' of the present embodiment includes only one interception net 110', and a plurality of interception members 120' are arranged on the interception net 110'. On the one hand, the axial length of the thrombus extraction stent 10' is relatively short, which is beneficial to remove the thrombus close to the closed end of the blood vessel or close to the part where the diameter of the blood vessel decreases. On the other hand, the interception net 110' and the interception member 120' cooperate to improve the radial interception performance.

[0164] It can be understood that in the embodiment, the filter membrane can be arranged on the interception net 110' to improve the interception performance. The filter membrane is arranged in the same way as the filter membrane 20 arranged on the second interception part 120, that is, the distal end of the filter membrane is connected to the distal end of the interception net 110' through the filter membrane fixing part 30', and the proximal end of the filter membrane is fixed on the expanded part of the interception net 110' in a sewing manner. Details are not described herein.

[0165] Any combination of the technical features of the above-described embodiments can be made. In order to make the description simple, all possible combinations of the technical features in the above-described embodiments are not described, however, as long as the combination of the technical features does not exist, it should be considered as the scope of the present disclosure.

[0166] The above only discloses the preferred embodiments of the present application, of course, cannot limit the scope of the right of the present application, therefore, the equivalent changes made according to the claims of the present application, still belongs to the scope covered by the present application.

Claims

1. A thrombectomy device, comprising: The thrombus extraction stent comprises an intercepting net and a plurality of intercepting members arranged on the intercepting net in a circumferential direction, one end of each of the intercepting members is connected to the intercepting net, and the other end is a free end. The thrombus extraction stent further comprises a first converging member connected to a proximal end of the intercepting net, in a natural state, the plurality of intercepting members are located outside the intercepting net, and each of the intercepting members is folded outward from the end connected to the intercepting net, the free end of the intercepting member faces the first converging member, and in a stretched state, the folded outward part can be folded toward the distal end, and the free end of the intercepting member faces the distal end. Alternatively, one end of each of the intercepting members connected to the intercepting net is a proximal end, and the other end is a distal end, in a natural state, the plurality of intercepting members are located inside the intercepting net, and in a stretched state, the plurality of intercepting members do not cross in the radial direction. The intercepting net comprises a first expansion part, the first expansion part comprises a plurality of first mesh units, and the plurality of first mesh units are connected to form a circumferentially closed mesh structure.

2. The thrombectomy device of claim 1, wherein, The intercepting members are arranged on the first mesh units, in a natural state, the plurality of intercepting members are located outside the intercepting net, and the intercepting members are folded outward from the end connected to the first mesh units, in a stretched state, the outward folded part can be folded toward the distal end, and the length of the intercepting member after the outward folded part is folded toward the distal end is less than the length of the first mesh unit.

3. The thrombectomy device of claim 1, wherein, The intercepting members are arranged on the first mesh units, each of the intercepting members comprises two intercepting rods, the two intercepting rods are connected to form a distal closed end, one end of the two intercepting rods away from the distal closed end is connected to the first mesh unit, and the distal closed end is a free end; or the intercepting member comprises two first intercepting rods and a second intercepting rod, two ends of the second intercepting rod are connected to one end of the two first intercepting rods respectively, and one end of the first intercepting rod away from the second intercepting rod is connected to the first mesh unit.

4. The thrombectomy device of claim 2 or 3, wherein, Each of the first mesh units comprises two first proximal rods, two first intermediate rods and two first distal rods, the two first proximal rods are connected at a proximal end, the two first distal rods are connected at a distal end, proximal ends of the two first intermediate rods are connected to distal ends of the two first proximal rods respectively, distal ends of the two first intermediate rods are connected to proximal ends of the two first distal rods respectively, and adjacent two first mesh units share one first intermediate rod.

5. The thrombectomy device of claim 4, wherein, The hardness of the intercepting members is less than the hardness of the first proximal rods, the first intermediate rods and the first distal rods.

6. The thrombectomy device of claim 4, wherein, The rod diameter of the intercepting members is less than the rod diameter of the first proximal rods, the first intermediate rods and the first distal rods.

7. The device of claim 4, wherein, The intercepting net is provided with a filter membrane, a proximal end of the filter membrane is open, and a proximal edge of the filter membrane has a wave-shaped structure with a plurality of convex parts, and adjacent two convex parts have a gap therebetween.

8. The thrombectomy device of claim 7, wherein, The thrombus extraction device further comprises a filter membrane fixing member, the filter membrane fixing member comprises a proximal end fixing part and a distal end fixing part connected with the proximal end fixing part, the proximal end fixing part is in a cylindrical shape, the distal end fixing part is in a truncated cone shape, the distal end fixing part extends out of the intercepting net, the proximal end fixing part is connected with the intercepting net, and the distal end of the filter membrane is clamped between the proximal end fixing part and the intercepting net.

9. The thrombectomy device of claim 8, wherein, The gap between the two adjacent protruding parts is located in the first mesh cell.

10. The thrombectomy device of claim 1, wherein, The intercepting net is a first intercepting part, and the thrombus extraction device further comprises a second intercepting part connected with the distal end of the first intercepting part, and the first intercepting part and the second intercepting part are connected through a flexible connecting member.

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