A suspension disinfectant, its preparation method and application

Abstract

The present invention relates to a suspension disinfection method, which includes a suspension disinfectant solution and its preparation method and application. The suspension disinfectant solution comprises the following components in percentage by weight: 10% decamethonium bromide, 5 - 15% diethylene glycol, 10 - 25% propylene glycol, 10 - 25% glycerol, 0.01 - 0.05% OP - 10, 0.1 - 0.5% nonylphenol polyoxyethylene ether, 0.1 - 0.5% fatty alcohol polyoxyethylene ether, 2 - 10% ethanol, 0.1 - 0.5% EDTA, 0 - 0.15% lemon essential oil. The suspension disinfection method of the present invention has excellent suspension performance, high safety, good stability, is non-toxic and pollution-free, can be used for space disinfection of livestock and poultry houses, and can also be directly used for disinfection of the environment, articles, etc.

Description

Technical Field

[0001] The present invention relates to a suspended disinfectant solution and a preparation method thereof, and an application of the suspended disinfectant solution as a livestock and poultry space disinfectant, an article surface disinfectant and / or a water body disinfectant. Background Art

[0002] With the development of the intensive farming level, people's awareness of biological safety prevention and control has gradually increased. Especially since the outbreak of African swine fever, the operation process of biological safety prevention and control in breeding enterprises has been gradually improved. Disinfection, as the main implementation means of biological safety prevention and control, can kill pathogens in the environment, cut off the transmission route, and prevent the spread or contagion of diseases. It is an important guarantee for the healthy development of livestock and poultry breeding, and an important measure to effectively prevent the infection of diseases in farms and control the outbreak of diseases. Therefore, disinfection has become an essential link in the biological safety prevention and control of farms.

[0003] At present, chemical disinfectants are mostly used for disinfection in farms. The disinfection methods mainly include spraying disinfection, wiping disinfection, fumigation disinfection, spraying disinfection and immersion disinfection. Among them, spraying disinfection and wiping disinfection are mainly for the surface disinfection of the environment or articles; immersion disinfection is mostly used for the disinfection of small corrosion-resistant objects. In the breeding environment, especially in the pens, some pathogenic bacteria can be transmitted through the air. Without a scientific and effective space disinfection method, it is difficult to achieve more thorough biological safety prevention and control. Fumigation disinfection, spraying disinfection and smoke disinfection are mostly used in pens. Fumigation disinfection usually uses formaldehyde as a disinfectant, but the application range of formaldehyde is relatively narrow and it can only be used for empty pen disinfection, and it has certain carcinogenicity, posing a great safety hazard. Spraying disinfection generally uses a spraying disinfection device equipped with a variety of chemical disinfectants for spraying disinfection, but the sprayed disinfectant droplets are relatively large and cannot be suspended in the space, and the disinfection effect is not ideal. Moreover, the spraying process will change the temperature and humidity in the pen and wet the surface of objects. Smoke disinfection is to ignite trichloroisocyanuric acid and dichloroisocyanuric acid smoke disinfectants disclosed in CN107821402A and CN101584319A to generate a large amount of disinfection smoke for disinfection. Although the use cost is low and the bactericidal effect is good, the irritation is relatively large, and when using, the solid disinfectant is ignited to generate smoke, posing a safety hazard.

[0004] With the continuous popularization of smoke disinfection equipment, glutaraldehyde-based disinfectants can also achieve smoke disinfection under certain conditions, but due to their safety problems, their application fields have certain limitations. Therefore, in order to solve the problem of space disinfection in farms and cut off the source of infection in the pen space, there is an urgent need for a suspended disinfectant with good space suspension performance, safety and high efficiency, so as to meet the needs of biological safety prevention and control in farms. Summary of the Invention

[0005] The object of the present invention is to provide a suspension disinfection method, which has excellent suspension performance, high safety, good stability, is non-toxic and pollution-free, can disinfect the space of livestock and poultry houses, and can also be directly used for disinfecting the environment, articles, etc.

[0006] To achieve the above object, on the one hand, the present invention provides a suspension disinfectant solution, which comprises the following components in percentage by weight: 10% decamethonium bromide, 5-15% diethylene glycol, 10-25% propylene glycol, 10-25% glycerol, 0.01-0.05% OP-10, 0.1-0.5% nonylphenol polyoxyethylene ether, 0.1-0.5% fatty alcohol polyoxyethylene ether, 2-10% ethanol, 0.1-0.5% EDTA, 0-0.15% lemon essential oil.

[0007] The content of the diethylene glycol can be 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14% or 15%.

[0008] The content of the propylene glycol can be 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24% or 25%.

[0009] The content of the glycerol can be 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24% or 25%.

[0010] The content of the OP-10 can be 0.01%, 0.02%, 0.03%, 0.04% or 0.05%.

[0011] The content of the nonylphenol polyoxyethylene ether can be 0.1%, 0.2%, 0.3%, 0.4% or 0.5%.

[0012] The content of the fatty alcohol polyoxyethylene ether can be 0.1%, 0.2%, 0.3%, 0.4% or 0.5%.

[0013] The content of the ethanol can be 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10%.

[0014] The content of the EDTA can be 0.1%, 0.2%, 0.3%, 0.4% or 0.5%.

[0015] The content of the lemon essential oil can be 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.10%, 0.11%, 0.12%, 0.13%, 0.14%, 0.15%.

[0016] In some embodiments of the present invention, the suspended disinfectant solution of the present invention comprises components in the following weight percentages: 10% decamethonium bromide, 5-15% diethylene glycol, 10-25% propylene glycol, 10-25% glycerol, 0.01-0.05% OP-10, 0.1-0.5% nonylphenol polyoxyethylene ether, 0.1-0.5% fatty alcohol polyoxyethylene ether, 2-10% ethanol, 0.1-0.5% EDTA, 0-0.15% lemon essential oil, and the balance is purified water.

[0017] In some embodiments of the present invention, the suspended disinfectant solution of the present invention comprises components in the following weight percentages: 10% decamethonium bromide, 8-12% diethylene glycol, 15-25% propylene glycol, 15-25% glycerol, 0.02-0.04% OP-10, 0.2-0.4% nonylphenol polyoxyethylene ether, 0.2-0.4% fatty alcohol polyoxyethylene ether, 4-8% ethanol, 0.2-0.4% EDTA, 0.01-0.12% lemon essential oil, and the balance is purified water.

[0018] In one embodiment of the present invention, the suspended disinfectant solution of the present invention comprises components in the following weight percentages: 10% decamethonium bromide, 10% diethylene glycol, 20% propylene glycol, 20% glycerol, 0.03% OP-10, 0.3% nonylphenol polyoxyethylene ether, 0.3% fatty alcohol polyoxyethylene ether, 5% ethanol, 0.3% EDTA, 0.01% lemon essential oil, and the balance is purified water.

[0019] In one embodiment of the present invention, the suspended disinfectant solution of the present invention comprises components in the following weight percentages: 10% decamethonium bromide, 8% diethylene glycol, 15% propylene glycol, 15% glycerol, 0.02% OP-10, 0.2% nonylphenol polyoxyethylene ether, 0.2% fatty alcohol polyoxyethylene ether, 4% ethanol, 0.2% EDTA, 0.01% lemon essential oil, and the balance is purified water.

[0020] In one embodiment of the present invention, the suspended disinfectant solution of the present invention comprises components in the following weight percentages: 10% decamethonium bromide, 12% diethylene glycol, 25% propylene glycol, 25% glycerol, 0.04% OP-10, 0.4% nonylphenol polyoxyethylene ether, 0.4% fatty alcohol polyoxyethylene ether, 8% ethanol, 0.4% EDTA, 0.12% lemon essential oil, and the balance is purified water.

[0021] The above-mentioned suspended disinfectant solution of the present invention has a long suspension time in the space of the disinfectant smoke generated by the smoke disinfectant, has a good disinfection and sterilization effect on the livestock and poultry space, the surface of articles and water bodies, and has no obvious toxic and side effects on humans and animals. In addition, the content of decamethonium bromide is stable after long-term placement of the suspended disinfectant solution, which is suitable for mass production.

[0022] To achieve the above object, on the other hand, the present invention provides a method for preparing a suspended disinfectant solution, which comprises the following steps:

[0023] (1) Prepare the raw materials of each component according to the components of the above-mentioned suspended disinfectant solution;

[0024] (2) Add the raw materials of each component into a liquid preparation tank while stirring, and continue to stir for 15 - 30 minutes after adding. Then add the remaining solvent and continue to stir for 10 - 30 minutes until uniform, thus obtaining the suspended disinfectant solution.

[0025] In some embodiments of the present invention, the solvent is purified water.

[0026] To achieve the above object, on another aspect, the present invention provides the application of the above-mentioned suspended disinfectant solution as a livestock and poultry space disinfectant, an article surface disinfectant, and / or a water body disinfectant. Detailed implementation manners

[0027] Preparation of the suspended disinfectant solution described in the present invention

[0028] Prepare the suspended disinfectant solutions 1 - 7 of Examples 1 - 7 respectively according to the components and related ratios listed in Table 1. The preparation method is as follows:

[0029] (1) Prepare the raw materials of each component according to the weight ratio in Table 1;

[0030] (2) Sequentially add the raw materials of each component into a liquid preparation tank while stirring, and continue to stir for 20 minutes after adding. Then add the remaining purified water and continue to stir for 15 minutes until uniform to obtain the suspended disinfectant solution.

[0031] Table 1 Component ratio table of the suspended disinfectant solution

[0032]

[0033] Note: Each suspended disinfectant solution in the table is made up to 100% with purified water.

[0034] Preparation of Comparative Solution 1

[0035] Components of Comparative Solution 1, by weight: 10% decamethonium bromide, 10% diethylene glycol, 20% propylene glycol, 20% glycerol, 5% nonylphenol polyoxyethylene ether, 5% fatty alcohol polyoxyethylene ether, 0.01% lemon essential oil, and the balance is purified water. Prepare Comparative Solution 1 with reference to the above method for preparing the suspended disinfectant solution.

[0036] Preparation of Comparative Solution 2

[0037] Component of Comparative Solution 2, by weight: 10% dequalinium bromide, 30% propylene glycol, 20% glycerol, 0.03% OP-10, 0.3% nonylphenol polyoxyethylene ether, 0.3% fatty alcohol polyoxyethylene ether, 5% ethanol, 0.3% EDTA, 0.01% lemon essential oil, and the balance is purified water. Prepare Comparative Solution 2 with reference to the above method for preparing the suspension disinfectant solution.

[0038] Preparation of Comparative Solution 3

[0039] Component of Comparative Solution 3, by weight: 10% dequalinium bromide, 5% ethylene glycol, 10% triethylene glycol, 25% propylene glycol, 0.03% OP-10, 0.3% nonylphenol polyoxyethylene ether, 0.3% fatty alcohol polyoxyethylene ether, 5% ethanol, 0.3% EDTA, 0.01% lemon essential oil, and the balance is purified water. Prepare Comparative Solution 3 with reference to the above method for preparing the suspension disinfectant solution.

[0040] Preparation of Comparative Solution 4

[0041] Component of Comparative Solution 4, by weight: 10% dequalinium bromide, 7% isopropyl alcohol, 0.03% OP-10, 0.3% nonylphenol polyoxyethylene ether, 0.3% fatty alcohol polyoxyethylene ether, 5% ethanol, 0.3% EDTA, 0.01% lemon essential oil, and the balance is ethylene glycol. Prepare Comparative Solution 4 with reference to the above method for preparing the suspension disinfectant solution.

[0042] Test Example 1. Content of Dequalinium Bromide and Storage Stability

[0043] Take the above suspension disinfectant solutions and comparative solutions, observe their appearance properties, and measure the content of dequalinium bromide in each suspension disinfectant solution and comparative solution according to Announcement No. 2369 of the Ministry of Agriculture and Rural Affairs. The results are shown in Table 2. Since Comparative Solution 1 showed the phenomena of solution turbidity and layering during storage, which did not meet the property requirements, Comparative Solution 1 was no longer evaluated in the subsequent suspension performance evaluation tests.

[0044] Table 2 Summary of Test Results of Suspension Disinfectant Solutions and Comparative Solutions

[0045]

[0046]

[0047] Test Example 2. Evaluation of Suspension Performance of Suspension Disinfectant Solutions and Comparative Solutions

[0048] Select a closed empty room with a space of about 50 m 3 as the test site. Smoke disinfect the prepared Suspension Disinfectant Solutions 1-7 and Comparative Solutions 2-4 in the closed empty room with a smoke disinfector, set the spraying time to 10 minutes, and at this time, the disinfectant solution concentration in the space is about 1.5 ml / m 3After the spraying is completed, start timing. At the same time, use a handheld dust particle counter to measure the particle size of the smoke particles and observe the visually observed suspension time of the smoke (h 1 ). In addition, after the spraying is completed, place culture plates containing Staphylococcus aureus (150 - 200 cfu / plate) at a height of 1 meter from the ground at the center of the room at 0, 1, 2, 4, and 6 hours. Open the lid of the plate, let it stand for 15 minutes, then cover the lid and take it out. Place it in an incubator at 37°C for 24 hours. Set up a control for each culture plate at each time point. The next day, calculate the sterilization rate at each time point based on the number of colonies on each petri dish, and thus obtain the duration for which the sterilization rate of the suspended disinfectants 1 - 7 and the comparison liquid 2 - 4 is > 90%, that is, their effective suspension time in the air (h 2 ). Combine the visually observed duration and the effective suspension time to evaluate the suspension performance of the suspended disinfectants 1 - 7 and the comparison liquid 2 - 4. The specific test results of the suspension performance evaluation are shown in Table 3 - 4.

[0049] Table 3 Particle size measurement results of the smoke particles of the suspended disinfectants and the comparison liquid

[0050]

[0051]

[0052] Table 4 Suspension time evaluation results of the suspended disinfectants and the comparison liquid

[0053]

[0054] The smaller the particle size of the smoke particles generated by the suspended disinfectant or the comparison liquid during smoking, the longer the time it can maintain in space. As can be seen from Table 3, under the same smoking conditions, among the smoke particles generated by the suspended disinfectant 5, the particles smaller than 10 μm account for 98%, which is the highest proportion among all solutions. Followed by the suspended disinfectant 3 and the suspended disinfectant 4.

[0055] As can be seen from Table 4, the suspended disinfectant 5 has the best suspension performance, with the longest visually observed suspension time and effective suspension time of the smoke. The suspended disinfectant 3 and the suspended disinfectant 4 are the next. The visually observed suspension time and effective suspension time of the comparison liquid 2 - 4 are significantly reduced, so the suspension performance of the comparison liquid 2 - 4 is significantly worse. Therefore, in the subsequent stability test, only the suspended disinfectants 1 - 7 are evaluated.

[0056] Test Example Three Determination of the Stability of the Suspended Disinfectant

[0057] The stability of seven solutions of suspension disinfectants 1-7 was evaluated by 60 °C high-temperature test, 40 °C accelerated test and 25 °C long-term test. The content of decamethonium bromide was determined according to Announcement No. 2369 of the Ministry of Agriculture and Rural Affairs. When the content of decamethonium bromide was 90.0%-110.0% of the labeled amount, it indicated that the stability of the solution met the requirements. During the stability test, the phenomena of turbidity and stratification of the solution were evaluated. The specific stability test results are shown in Tables 5-9. At 6 months and 12 months of long-term stability evaluation, the suspension performance of each suspension disinfectant was evaluated according to the method in Example 2. The specific test results are shown in Table 10.

[0058] Table 5 Test Results of Each Suspension Disinfectant in 60 °C High-Temperature Test

[0059]

[0060] Table 6 Determination Results of the Content of Each Suspension Disinfectant in 40 °C Accelerated Test

[0061]

[0062]

[0063] Table 7 Observation Results of the Properties of Each Suspension Disinfectant in 40 °C Accelerated Test

[0064]

[0065] Table 8 Determination Results of the Content of Each Suspension Disinfectant in 25 °C Long-Term Test

[0066]

[0067] Table 9 Observation Results of the Properties of Each Suspension Disinfectant in 25 °C Long-Term Test

[0068]

[0069] Table 10 Evaluation Results of the Suspension Performance of Each Suspension Disinfectant in 25 °C Long-Term Test

[0070]

[0071] According to the regulations in the "Technical Guidelines for the Study of the Stability of Veterinary Chemical Drugs", it can be seen from the data in Tables 5-9 that the suspension disinfectants 2-5 have better stability in terms of the content of decamethonium bromide and the appearance properties, and meet the requirements in each stability evaluation test. It can be seen from the data in Table 10 that after long-term storage, the suspension performance of suspension disinfectants 3-5 basically remains unchanged, so their suspension performance is relatively stable. Among them, the suspension performance of suspension disinfectant 5 is the most stable. Therefore, the laboratory disinfection effect evaluation and clinical effect verification were carried out with this suspension disinfectant 5.

[0072] Test Example 4 Laboratory Disinfection Effect Evaluation of Suspension Disinfectant

[0073] Test drug: Suspended disinfectant solution 5.

[0074] Test strains: Escherichia coli 8099, Staphylococcus aureus ATCC6538.

[0075] Test method: Pipette 0.5 ml of the test bacterial solution (10 6 -10 7 cfu / ml) and mix it evenly in 4.5 ml of the 500-fold, 1000-fold, 2000-fold, 4000-fold, 8000-fold, and 12800-fold dilutions of the suspended disinfectant solution 5 for 5 minutes. Immediately, take 0.5 ml of the bacterial-drug mixture and add it to 4.5 ml of the neutralizer solution, mix well and neutralize for 10 minutes, and take the neutralized product solution for viable bacteria counting. At the same time, use normal saline to replace the disinfectant dilution, and perform other operations according to the above steps as the bacterial solution control group. Dilute the neutralized product solution 10-fold and 100-fold with normal saline, and take the 10-fold and 100-fold dilutions for viable bacteria counting. Use normal saline to replace the disinfectant and bacterial solution respectively, and perform the remaining operations according to the above steps as the negative control group. The negative control group is directly plated for counting.

[0076] Bactericidal effect evaluation and calculation method: Bactericidal rate (P t ) = [(N 0 -N t ) / N 0 ×100%, where N 0 = the number of viable bacteria in the bacterial solution control group, N t = the number of viable bacteria in the test group. When the bactericidal rate of the highest dilution multiple of the disinfection solution > 99.9%, this dilution multiple can be determined as the effective bactericidal concentration of the disinfectant. The test results of the disinfection effects of each group of solutions on the three bacteria are shown in Table 11.

[0077] Table 11 Test results of the disinfection effects of the suspended disinfectant solution on 2 bacteria

[0078]

[0079]

[0080] Test Example Five Clinical Effect Verification of Different Application Scenarios of the Suspended Disinfectant Solution

[0081] The suspended disinfectant solution is mainly used for the disinfection of livestock and poultry houses and the disinfection of hatching rooms for breeding eggs in farms. For this application scenario, a clinical effect verification test was carried out using the suspended disinfectant solution 5.

[0082] 5.1 Evaluation of the disinfection effect of the pens

[0083] Test drug: Suspended disinfectant solution 5.

[0084] Test site: The brooding house of a chicken farm in Henan.

[0085] The coop to be disinfected is about 1200m 3 , Before disinfection, sampling points were arranged in the coop to be disinfected according to the relevant regulations in DB11 / T1429-2017 and GB / T18204.3, and surface samples of objects in the coop and natural settling bacteria in the air were collected. Then, the disinfection equipment was turned on to carry out smoke disinfection with the suspended disinfectant solution 5. During the disinfection process, the doors and windows in the coop were closed and the airtightness of the coop was good. After disinfection, it was kept closed for another 3h, and then samples after disinfection were collected according to the sampling method before disinfection. All samples were taken back to the laboratory for viable count detection. The average colony count of all sampling points was used as the average colony count of the sample, and the sterilization rate was calculated based on the colony counts of the samples before and after disinfection. The specific formula is as follows. The disinfection effect was evaluated by the sterilization rate.

[0086] Sterilization rate = (N 0 -N t ) / N 0 ×100%

[0087] In the formula: N 0 represents the average colony count of the sample before disinfection; N t represents the average colony count of the sample after disinfection.

[0088] The results of on-site disinfection tests are shown in Table 12.

[0089] Table 12 Test results of the disinfection effect of the suspended disinfectant solution in the coop

[0090]

[0091]

[0092] It can be seen from the data in Table 12 that when the suspended disinfectant solution 5 is used for coop disinfection, the sterilization rate of the natural bacteria on the surface of the coop to be disinfected is 90.8%-93.8%, and the sterilization rate of the natural bacteria in the air is 98.9%. According to the disinfection effect evaluation table in DB11 / T1429-2017, this disinfectant has a better disinfection effect on the natural bacteria in the coop.

[0093] In addition, during the subsequent observation, no irritation or toxic side effects of the disinfectant solution on the chicks bred in the coop and the relevant staff were found.

[0094] 5.2 Evaluation of the disinfection effect of the suspended disinfectant solution in the hatching room

[0095] Test drug: Suspended disinfectant solution 5.

[0096] Test site: The breeding egg hatching room of a chicken farm in Henan.

[0097] The coop to be disinfected is about 150m 3, before disinfection, surface samples of indoor objects and egg surfaces were collected in the hatching room to be disinfected. Then, the disinfection equipment was turned on to perform smoke disinfection with the suspended disinfectant solution 5. During the disinfection process, the doors and windows in the hatching room were closed and the enclosure had good airtightness. After disinfection, it continued to be closed for 30 minutes, and then samples after disinfection were collected according to the sampling method before disinfection. All samples were taken back to the laboratory for viable bacteria count detection. The average colony count of all sampling points was used as the average colony count of the sample, and the sterilization rate was calculated based on the colony counts of the samples before and after disinfection. The specific formula is as follows. The disinfection effect was evaluated by the sterilization rate.

[0098] Sterilization rate = (N 0 - N t ) / N 0 × 100%

[0099] In the formula: N 0 represents the average colony count of the sample before disinfection; N t represents the average colony count of the sample after disinfection.

[0100] The results of the on-site disinfection test are shown in Table 13.

[0101] Table 13 Test results of the disinfection effect of the suspended disinfectant solution in the hatching room

[0102]

[0103] It can be seen from the data in Table 13 that the sterilization rate of the suspended disinfectant solution 5 against the natural bacteria on the hatching room environment and egg surfaces is 92.9% - 100%, and the disinfection effect is relatively good.

[0104] In addition, during the subsequent observation, no irritation or toxic side effects of the disinfectant solution on the hatching eggs, hatched chicks, and related staff were found.

Claims

1. A suspension disinfectant, which comprises the following components in percentage by weight: 10% decamethonium bromide, 5-15% diethylene glycol, 10-25% propylene glycol, 10-25% glycerol, 0.01-0.05% OP-10, 0.1-0.5% nonylphenol polyoxyethylene ether, 0.1-0.5% fatty alcohol polyoxyethylene ether, 2-10% ethanol, 0.1-0.5% EDTA, 0-0.15% lemon essential oil, and the balance being purified water.

2. The suspension disinfectant according to claim 1, which comprises the following components in percentage by weight: 10% decamethonium bromide, 8-12% diethylene glycol, 15-25% propylene glycol, 15-25% glycerol, 0.02-0.04% OP-10, 0.2-0.4% nonylphenol polyoxyethylene ether, 0.2-0.4% fatty alcohol polyoxyethylene ether, 4-8% ethanol, 0.2-0.4% EDTA, 0.01-0.12% lemon essential oil, and the balance being purified water.

3. The suspension disinfectant according to claim 2, which comprises the following components in percentage by weight: 10% decamethonium bromide, 10% diethylene glycol, 20% propylene glycol, 20% glycerol, 0.03% OP-10, 0.3% nonylphenol polyoxyethylene ether, 0.3% fatty alcohol polyoxyethylene ether, 5% ethanol, 0.3% EDTA, 0.01% lemon essential oil, and the balance being purified water.

4. The suspension disinfectant according to claim 2, which comprises the following components in percentage by weight: 10% decamethonium bromide, 8% diethylene glycol, 15% propylene glycol, 15% glycerol, 0.02% OP-10, 0.2% nonylphenol polyoxyethylene ether, 0.2% fatty alcohol polyoxyethylene ether, 4% ethanol, 0.2% EDTA, 0.01% lemon essential oil, and the balance being purified water.

5. The suspension disinfectant according to claim 2, which comprises the following components in percentage by weight: 10% decamethonium bromide, 12% diethylene glycol, 25% propylene glycol, 25% glycerol, 0.04% OP-10, 0.4% nonylphenol polyoxyethylene ether, 0.4% fatty alcohol polyoxyethylene ether, 8% ethanol, 0.4% EDTA, 0.12% lemon essential oil, and the balance being purified water.

6. A preparation method of a suspension disinfectant, which comprises the following steps: (1) Prepare the raw materials of each component according to the suspension disinfectant described in any one of claims 1-5; (2) Add the raw materials of each component into a liquid mixing tank while stirring, continue stirring for 15-30 minutes after adding, then add the balance solvent, and continue stirring for 10-30 minutes until uniform, thus obtaining the suspension disinfectant.

7. Use of the suspension disinfectant according to any one of claims 1-5 as a livestock and poultry space disinfectant, an article surface disinfectant and / or a water body disinfectant.

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