A pure oil composition containing menthyl glycol and its application

Abstract

The present invention discloses a pure oil composition containing menthyl glycol and its application. The raw materials for preparing the pure oil composition include, by weight, 2-10 parts of menthyl glycol, 3-11 parts of solvent A, and 4-42 parts of solvent B. The composition solves the problem of menthyl glycol being volatile at high temperatures and precipitating raw materials at low temperatures, making the preparation of the finished mosquito repellent product difficult. The composition can be dissolved by simply adding the solvents in order at 40-55°C.

Description

Technical Field

[0001] The present invention relates to the field of A01N31 / 06, and more particularly to a pure oil composition containing menthanediol and applications thereof. Background Art

[0002] Mosquitoes are common insects with piercing-sucking mouthparts that feed on human blood. Mosquito bites can cause discomfort, such as redness, swelling, and itching. Furthermore, mosquitoes are also intermediate hosts for serious infectious diseases such as dengue fever, malaria, and yellow fever. Therefore, daily mosquito repellent is essential, especially during hot summer days when outdoor activities require a mosquito repellent spray, which is convenient to carry. Menthylene glycol is an effective plant-derived mosquito repellent ingredient. The material exhibits a crystalline precipitate that separates upon standing.

[0003] CN105816362B discloses a mosquito repellent for infants and young children. The raw materials include menthyl glycol, dipropylene glycol, propylene glycol or propylene glycol or butylene glycol, PEG40 hydrogenated castor oil, and deionized water. It does not contain pesticide repellent ingredients such as chlorpyrifos or DEET, does not contain ethanol, essence, or preservatives, has a good mosquito repellent effect, and is non-irritating to the skin of infants and young children. Its principle characteristic is that it is alcohol-soluble, incompatible with pure water and most oils or has poor compatibility. It precipitates when left to stand, and its stability test is difficult to pass. It is difficult to add high content to the formula to achieve mosquito repellent effect. CN112980607A discloses a long-lasting mosquito repellent laundry liquid and its preparation method. By preparing menthyl glycol into a capsule microemulsion, its stability is guaranteed and the effectiveness of mosquito repellent is achieved. However, the preparation method is relatively complicated and the cost is high. Summary of the Invention

[0004] In response to the above problems, the present invention discloses a pure oil composition containing menthyl glycol. The raw materials for preparation include, by mass, 2-10 parts of menthyl glycol, 3-11 parts of solvent A, and 4-42 parts of solvent B.

[0005] In one embodiment, the solvent A is selected from saturated fatty acids and / or unsaturated fatty acids.

[0006] Preferably, the solvent A is a saturated fatty acid.

[0007] More preferably, the saturated fatty acid is C6-C 20 Saturated fatty acids, including but not limited to caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid, stearic acid, and isostearic acid.

[0008] More preferably, the solvent A is isostearic acid.

[0009] In one embodiment, the solvent B is selected from any one of esters, alcohols, carboxylic acids, and ketones.

[0010] Preferably, the solvent B is an ester.

[0011] Further preferably, the esters are organic acid esters, including but not limited to isopropyl myristate, isopropyl palmitate, ethylhexyl palmitate, glyceryl stearate, and caprylic / capric triglyceride.

[0012] More preferably, the solvent B is isopropyl myristate.

[0013] The second aspect of the present invention discloses the application of the composition, which is applied to mosquito repellent products.

[0014] The raw materials for preparing the mosquito repellent product include, by weight: 8-63 parts of a pure oil composition, 30-92 parts of white oil, 0.1-1 part of a cooling agent, and 0.1-2 parts of a plant extract oil.

[0015] The mass standard of the raw materials for preparing the mosquito repellent product is the same as that of the pure oil composition.

[0016] In one embodiment, the white oil is cosmetic grade white oil, including but not limited to white oil 5#, 10#, 15#, and 26#.

[0017] In one embodiment, the cooling agent is selected from any one of borneol and its derivatives, camphor and its derivatives, and mint and its derivatives.

[0018] Preferably, the cooling agent is mint and its derivatives.

[0019] More preferably, the cooling agent is a mint derivative, including but not limited to menthyl lactate, menthol lactate, and menthone glycerol ketal; more preferably, menthol lactate.

[0020] In one embodiment, the plant extract oil is selected from one or more of bergamot fruit oil, evening primrose oil, linseed oil, macadamia seed oil, olive oil, melon seed oil, safflower seed oil, jojoba seed oil, orange oil, lemon peel oil, tangerine peel oil, bergamot oil, and lemon eucalyptus oil; preferably lemon eucalyptus oil.

[0021] The preparation method of the pure oil mosquito repellent product comprises the following steps:

[0022] (1) Menthyl glycol, solvent A, cooling agent, and plant extract oil are stirred and heated to dissolve until transparent and free of particles;

[0023] (2) Add solvent B and stir until transparent and uniform;

[0024] (3) Add white oil and stir until a uniform solution is obtained.

[0025] In one embodiment, the heating temperature in step (1) is 40-55°C, preferably 50°C.

[0026] Menthylene glycol is an effective mosquito repellent raw material extracted from plants. The raw material has the characteristics of crystalline precipitation. The raw material will precipitate when left standing. Its principle characteristic is that it is alcohol-soluble. It is incompatible or has poor compatibility with pure water and most oils. The dosage form of menthylene glycol mosquito repellent products commonly used on the market is solubilized with alcohol or solubilizers. However, both alcohol and solubilizers will bring irritation risks when added in high amounts. Through extensive research, the applicant discovered a pure oil system mosquito repellent product, that is, menthyl glycol can be dissolved in a high concentration in a solvent A and solvent B system, especially solvent A is isostearic acid and solvent B is isopropyl myristate. It is not only stable without the addition of alcohol and solubilizers, but also solves the problem that menthyl glycol is volatile at high temperatures and precipitates raw materials at low temperatures, making the preparation of mosquito repellent products difficult. It only requires adding solvents in order at 40-55°C. The applicant believes that the possible reason is that the structure of menthyl glycol is relatively similar to that of isostearic acid, and the branched structure of isostearic acid can weaken the intramolecular interaction due to the steric effect. The addition of isopropyl myristate further reduces the steric hindrance, and can form an oil film that is not easy to penetrate, making the product more mild.

[0027] Beneficial effects

[0028] 1. Menthyl glycol can be dissolved in solvent A and solvent B at high concentrations and can be stable without precipitation without adding alcohol or solubilizer.

[0029] 2. The problem that menthyl glycol is volatile at high temperatures and precipitates out raw materials at low temperatures, making the preparation of mosquito repellent products difficult, is solved. It can be dissolved by adding solvents in order at 40-55°C.

[0030] 3. This product can form an oil film that is not easily penetrated and is more gentle.

[0031] 4. The prepared product is easy and convenient to use, and can be directly sprayed and spread evenly.

[0032] 5. The production cost is low, the preparation method is simple, the production efficiency is high, and the production energy consumption can be greatly reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] Figure 1 Mosquito repellent product stability test results diagram, the left side is the main view, and the right side is the top view. DETAILED DESCRIPTION

[0034] Example 1

[0035] Screen the compatibility of each oil with menthyl glycol.

[0036] The specific method is: take 1g of menthyl glycol, add 1g of the following 7 kinds of oils respectively: isopropyl myristate, isopropyl palmitate, ethylhexyl palmitate, diethylhexyl carbonate, isostearic acid, white oil, sunflower seed oil, heat until dissolved and transparent, and observe after cooling.

[0037]

[0038]

[0039] According to the precipitation rate after cooling and standing, isostearic acid and menthyl glycol were screened out as having the best compatibility, and the others all precipitated obviously.

[0040] Example 2

[0041] Screen the compatibility of each oil with isostearic acid and menthyl glycol.

[0042] Take 1g of menthyl glycol and 1g of isostearic acid, and add 1g of the following 6 oils respectively: isopropyl myristate, isopropyl palmitate, ethylhexyl palmitate, diethylhexyl carbonate, white oil, and sunflower seed oil. Heat until dissolved and transparent, and observe after cooling.

[0043]

[0044]

[0045] 1g of isostearic acid + 1g of menthyl glycol + 1g of isopropyl myristate will become transparent when left to stand, and the rest will precipitate after cooling.

[0046] Application Example 1

[0047] This application example 1 discloses a pure oil mosquito repellent product. The raw materials for its preparation are, by weight, 6 parts of menthyl glycol, 7 parts of isostearic acid, 10 parts of isopropyl myristate, 0.3 parts of menthol lactate, 2 parts of lemon eucalyptus oil, and the remainder is white oil, with a total of 100 parts by weight.

[0048] The lemon eucalyptus oil was purchased from Kuishi Fine Chemicals, model number M168 natural mosquito repellent extract.

[0049] The white oil was purchased from Zhejiang Zhengxin Petroleum Technology Co., Ltd., and the model was 26# white oil.

[0050] The second aspect of this application example discloses a method for preparing the pure oil mosquito repellent product:

[0051] (1) Menthyl glycol, isostearic acid, menthol lactate, and lemon eucalyptus oil were stirred and heated to dissolve until transparent and free of particles at 50°C;

[0052] (2) Add isopropyl myristate to the above solution and stir until transparent and uniform;

[0053] (3) Add white oil to the remaining mixture and stir until uniform.

[0054] Application Example 2

[0055] This application example 2 discloses a pure oil mosquito repellent product. The raw materials for its preparation are, by weight, 10 parts of menthyl glycol, 10 parts of isostearic acid, 22 parts of isopropyl myristate, 0.3 parts of menthol lactate, 2 parts of lemon eucalyptus oil, and the remainder is white oil, with a total of 100 parts by weight.

[0056] The lemon eucalyptus oil was purchased from Kuishi Fine Chemicals, model number M168 natural mosquito repellent extract.

[0057] The white oil was purchased from Zhejiang Zhengxin Petroleum Technology Co., Ltd., and the model was 26# white oil.

[0058] The second aspect of this application example discloses a method for preparing the pure oil mosquito repellent product:

[0059] (1) Menthyl glycol, isostearic acid, menthol lactate, and lemon eucalyptus oil were stirred and heated to dissolve until transparent and free of particles at 50°C;

[0060] (2) Add isopropyl myristate to the above solution and stir until transparent and uniform;

[0061] (3) Add white oil to the remaining mixture and stir until uniform.

[0062] Application Example 3

[0063] This application example 3 discloses a pure oil mosquito repellent product. The raw materials for its preparation are, by weight, 6 parts of menthyl glycol, 2 parts of isostearic acid, 15 parts of isopropyl myristate, 0.3 parts of menthol lactate, 2 parts of lemon eucalyptus oil, and the remainder is white oil, with a total of 100 parts by weight.

[0064] The lemon eucalyptus oil was purchased from Kuishi Fine Chemicals, model number M168 natural mosquito repellent extract.

[0065] The white oil was purchased from Zhejiang Zhengxin Petroleum Technology Co., Ltd., and the model was 26# white oil.

[0066] The second aspect of this application example discloses a method for preparing the pure oil mosquito repellent product:

[0067] (1) Menthyl glycol, isostearic acid, menthol lactate, and lemon eucalyptus oil were stirred and heated to dissolve until transparent and free of particles at 50°C;

[0068] (2) Add isopropyl myristate to the above solution and stir until transparent and uniform;

[0069] (3) Add white oil to the remaining mixture and stir until uniform.

[0070] Performance Testing

[0071] Stability: The mosquito repellent products of Application Examples 1 and 2 were tested for stability at five different temperatures. Stability was observed for one month at -18°C (frozen) and 48°C (hot), and for three months at 4°C (cold), room temperature (25°C), and 40°C. The results are summarized in Table 1 below.

[0072]

Claims

1. A pure oil mosquito repellent product, characterized in that: The raw materials for preparing the mosquito repellent product are, by mass, 6 parts of menthyl glycol, 7 parts of isostearic acid, 10 parts of isopropyl myristate, 0.3 parts of menthol lactate, 2 parts of lemon eucalyptus oil, and the remainder is white oil, with a total of 100 parts by mass.

2. A pure oil mosquito repellent product, characterized in that: The raw materials for preparing the mosquito repellent product are, by mass, 10 parts of menthyl glycol, 10 parts of isostearic acid, 22 parts of isopropyl myristate, 0.3 parts of menthol lactate, 2 parts of lemon eucalyptus oil, and the remainder is white oil, with a total of 100 parts by mass.

3. The pure oil mosquito repellent product according to claim 1 or 2, characterized in that: The white oil is cosmetic grade white oil.

4. The method for preparing the pure oil mosquito repellent product according to claim 1 or 2, characterized in that: The preparation method of the mosquito repellent product comprises the following steps: (1) Stir and heat menthyl glycol, isostearic acid, menthol lactate, and lemon eucalyptus oil until transparent and free of particles; (2) Add isopropyl myristate and stir until transparent and uniform; (3) Add white oil and stir until the solution becomes uniform.

5. The preparation method according to claim 4, characterized in that The heating temperature in step (1) is 40-55°C.

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