Subcutaneous injection port assembly

Abstract

A subcutaneous injection interface assembly (10) is disclosed. The subcutaneous injection interface assembly (10) includes a needle hub (14), a cannula (12), and a cannula carrier (100). The cannula carrier (100) is non-removably connected to the cannula (12). The cannula carrier (100) can be controllably separated from the needle hub (14).

Description

Technical Field

[0001] The present disclosure generally relates to subcutaneous injection interface assemblies. Background Art

[0002] This section provides background information related to the present disclosure and is not necessarily prior art.

[0003] While known subcutaneous injection port assemblies have proven acceptable for various applications, such subcutaneous injection port assemblies are still susceptible to improvement to improve their overall performance and reduce their cost.Therefore, there is a need to develop subcutaneous injection port assemblies that advance the art. Summary of the Invention

[0004] This section provides a general summary of the disclosure, and is not a comprehensive disclosure of its full scope or all of its features.

[0005] In one aspect, the present invention provides a subcutaneous injection interface assembly that may include: a needle hub; a cannula; and a cannula carrier, wherein the cannula carrier is non-removably connected to the cannula and controllably detachable from the needle hub. In another embodiment, the subcutaneous injection interface assembly may further include an adhesive that connects the cannula to the cannula carrier. In yet another embodiment of the subcutaneous injection interface assembly, the cannula carrier may include an adhesive deposition channel, and the adhesive may be deposited into the adhesive deposition channel of the cannula carrier.

[0006] In one embodiment of the subcutaneous injection interface assembly of the present invention, the sleeve holder may include at least one leg; further, at least one leg of the sleeve holder may include a barb portion, and the needle hub may include a groove sized to receive the barb portion of the at least one leg.

[0007] In an embodiment of the present invention, the cannula of the subcutaneous injection interface assembly can be disposed within a needle hub channel extending through the needle hub and a cannula carrier channel extending through the cannula carrier. In another embodiment, the outer surface of the cannula can be fixed to the inner surface defining the needle hub channel.

[0008] In another aspect of the subcutaneous injection interface assembly, a first portion of the outer surface of the cannula can be disposed in a spaced relationship relative to a first inner surface portion defining a first cannula holder passageway portion of the cannula holder, and a second portion of the outer surface of the cannula can be disposed adjacent to a second inner surface portion defining a second cannula holder passageway portion of the cannula holder to fluidically seal the second cannula holder passageway portion of the cannula holder. Furthermore, the cannula holder can include a head portion and at least one leg portion defined by a body.

[0009] In another aspect, the present invention provides a subcutaneous injection interface assembly comprising (a) a first subcutaneous injection interface assembly portion defined by a needle hub; and (b) a second subcutaneous injection interface assembly portion detachably connected to the first subcutaneous injection interface assembly portion, wherein the second subcutaneous injection interface assembly portion is defined by (i) a cannula and (ii) a cannula carrier non-removably connected to the cannula, wherein the cannula carrier is controllably separable from the needle hub. The subcutaneous injection interface assembly may also include an adhesive connecting the cannula to the cannula carrier. In yet another aspect, the cannula carrier may include an adhesive deposition channel, and the adhesive may be deposited into the adhesive deposition channel of the cannula carrier.

[0010] In another embodiment of the subcutaneous injection interface assembly of the present invention, the cannula carrier may include at least one leg. Furthermore, the at least one leg of the cannula carrier may include a barb, and the needle hub may include a recess sized to receive the barb of the at least one leg.

[0011] In another embodiment, the sleeve of the subcutaneous injection interface assembly can be disposed in a needle hub channel extending through the needle hub and a sleeve carrier channel extending through the sleeve carrier. In addition, the outer surface of the sleeve can be fixed to the inner surface defining the needle hub channel.

[0012] In another embodiment of the subcutaneous injection interface assembly, a first portion of the outer surface of the cannula can be disposed in a spaced relationship relative to a first inner surface portion defining a first cannula holder passageway portion of the cannula holder, and a second portion of the outer surface of the cannula can be disposed adjacent to a second inner surface portion defining a second cannula holder passageway portion of the cannula holder to fluidically seal the second cannula holder passageway portion of the cannula holder. Furthermore, the cannula holder can include a head portion and at least one leg portion defined by a body.

[0013] Another embodiment of the present invention is a method comprising (a) providing a cannula holder, a cannula, and a needle hub; (b) inseparably coupling the cannula holder to the cannula; and (c) coupling the cannula holder to the needle hub, wherein the cannula holder is controllably separable from the needle hub. The method may further comprise separably coupling the needle hub to an injection gun and inserting the cannula into the flesh of a subject. Additional method steps may comprise subjecting one or both of the cannula and the cannula holder to one or more radial forces relative to a central axis extending through the cannula and the cannula holder to mechanically separate the cannula holder from the needle hub, whereby (i) the needle hub remains separably coupled to the injection gun, (ii) the cannula is removably disposed within the flesh of the subject, and (iii) the cannula holder is disposed adjacent an outer surface of the flesh of the subject.

[0014] In another embodiment, a method of the present invention may include positioning a cannula holder adjacent to an outer surface of a subject's flesh; grasping the cannula holder; and applying force to the cannula holder to remove the cannula from the subject's flesh. Another method step may include separating the needle hub from the injection gun. Additionally, the cannula holder may include a high-visibility dye or pigment. In another embodiment, applying force may cause one or more legs of the cannula holder to expand.

[0015] The details of one or more implementations of the present disclosure are set forth in the accompanying drawings and the description below. Other aspects, features, and advantages will be apparent from the description and drawings, and from the claims. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The drawings described herein are for illustrative purposes only of selected configurations and not all possible implementations, and are not intended to limit the scope of the present disclosure.

[0017] 1 is an exploded perspective view of an exemplary subcutaneous injection interface assembly.

[0018] 2 is a perspective view of an exemplary cannula of the subcutaneous injection interface assembly of FIG. 1 .

[0019] 3 is a front perspective view of an exemplary needle hub of the subcutaneous injection interface assembly of FIG. 1 .

[0020] 4 is a rear perspective view of the needle hub of FIG. 2 .

[0021] 5 is another front perspective view of the needle hub of FIG. 2 .

[0022] FIG. 6 is a side view of the needle hub of FIG. 2 .

[0023] 7 is a cross-sectional view of the needle hub according to line 7 - 7 of FIG. 6 .

[0024] FIG. 8A is another side view of the needle hub of FIG. 2 .

[0025] FIG. 8B is a top view of the needle hub according to arrow 8B of FIG. 8A .

[0026] FIG. 9A is another side view of the needle hub of FIG. 2 .

[0027] FIG. 9B is a top view of the needle hub according to arrow 9B of FIG. 9A .

[0028] FIG. 10 is a bottom view of the needle hub according to arrow 10 of FIG. 8A or 9A .

[0029] 11A is a cross-sectional view of a subassembly of the subcutaneous injection interface assembly arranged in a first partially assembled state according to line 11A-11A of FIG. 1 .

[0030] 11B is a cross-sectional view of the partially assembled subcutaneous injection interface subassembly of FIG. 11A arranged in a second partially assembled state.

[0031] 11C is a cross-sectional view of the assembled subcutaneous injection interface subassembly of FIG. 11B according to line 11 ′- 11 ′ in FIG. 12 .

[0032] 12 is an assembled front perspective view of the subcutaneous injection interface subassembly of FIG. 11C .

[0033] 13 is a top view of the subcutaneous injection port subassembly according to arrow 13 of FIG. 12 .

[0034] 14 is a bottom view of the subcutaneous injection interface subassembly according to arrow 14 of FIG. 12 .

[0035] 15 is an assembled rear perspective view of the subcutaneous injection interface subassembly of FIG. 11C .

[0036] 16 is another assembled front perspective view of the subcutaneous injection port subassembly of FIG. 11C .

[0037] 17 is a side view of the subcutaneous injection interface subassembly of FIG. 11C .

[0038] 18 is a front perspective view of an exemplary cannula carrier of the subcutaneous injection interface assembly of FIG. 1 .

[0039] 19 is another front perspective view of the example ferrule carrier of FIG. 18 rotated 90°.

[0040] 20 is another front perspective view of the example ferrule carrier of FIG. 19 rotated 90°.

[0041] 21 is another front perspective view of the example ferrule carrier of FIG. 20 rotated 90°.

[0042] 22 is a rear perspective view of the ferrule carrier of FIG. 18 .

[0043] 23 is another front perspective view of the ferrule carrier of FIG. 18 .

[0044] FIG. 24 is a top view of the cannula carrier according to arrow 24 of any of FIGs. 18-23 .

[0045] 25 is a bottom view of the cannula carrier according to arrow 25 of any of FIGS. 18-23 .

[0046] 26A is a side view of the cannula carrier of FIG. 18 .

[0047] 26B is a side view of the cannula carrier of FIG. 26A rotated 45°.

[0048] 26C is a side view of the cannula carrier of FIG. 26B rotated 45°.

[0049] 26D is a side view of the cannula carrier of FIG. 26C rotated 45°.

[0050] 26E is a side view of the cannula carrier of FIG. 26D rotated 45°.

[0051] 26F is a side view of the cannula carrier of FIG. 26E rotated 45°.

[0052] 26G is a side view of the cannula carrier of FIG. 26F rotated 45°.

[0053] 26H is a side view of the cannula carrier of FIG. 26G rotated 45°.

[0054] 27A is a bottom view of the ferrule carrier corresponding to FIG. 26A .

[0055] 27B is a bottom view of the cannula carrier corresponding to FIG. 26B .

[0056] 27C is a bottom view of the cannula carrier corresponding to FIG. 26C .

[0057] 27D is a bottom view of the cannula carrier corresponding to FIG. 26D .

[0058] 27E is a bottom view of the cannula carrier corresponding to FIG. 26E .

[0059] 27F is a bottom view of the cannula carrier corresponding to FIG. 26F .

[0060] 27G is a bottom view of the cannula carrier corresponding to FIG. 26G .

[0061] 27H is a bottom view of the cannula carrier corresponding to FIG. 26H .

[0062] 28 is an exploded front perspective view of a portion of the subcutaneous injection interface assembly of FIG. 1 including the cannula of FIG. 2 , the needle hub of FIG. 3-10 , and the cannula carrier of FIG. 18-27H .

[0063] FIG. 29 is a cross-sectional view taken along line 29 - 29 of FIG. 28 .

[0064] 30 is another cross-sectional view according to FIG. 29 , illustrating the cannula carrier disposed about the subcutaneous injection interface subassembly of FIG. 11C-17 .

[0065] 31 is another cross-sectional view according to FIG. 30 , showing adhesive metered into the channel portion of the cannula carrier for non-removably attaching the cannula carrier to the cannula of the subcutaneous injection port subassembly.

[0066] 32 is another cross-sectional view according to FIG. 31 showing light curing the adhesive that irremovably joins the cannula carrier to the cannula of the subcutaneous injection port subassembly.

[0067] 33 is an assembled rear perspective view of the subcutaneous injection interface assembly of FIG. 1 .

[0068] 34 is another assembled front perspective view of the subcutaneous injection interface assembly of FIG. 1 .

[0069] 35A is a perspective cross-sectional view taken along line 35 - 35 of the front perspective view of the subcutaneous injection interface assembly according to FIG. 34 , the subcutaneous injection interface assembly being arranged in a rest orientation.

[0070] 35B is a side cross-sectional view of the assembled subcutaneous injection interface assembly according to arrow 35B of FIG. 35A .

[0071] 36A is another perspective cross-sectional view of the front perspective view of the subcutaneous injection interface assembly according to FIG. 35A , the subcutaneous injection interface assembly being arranged in a biased orientation.

[0072] 36B is a side cross-sectional view of the assembled subcutaneous injection interface assembly according to arrow 36B of FIG. 36A .

[0073] 37A is another perspective cross-sectional view of the front perspective view of the subcutaneous injection interface assembly according to FIG. 35A , the subcutaneous injection interface assembly being arranged in a disengaged orientation.

[0074] 37B is a side cross-sectional view of the assembled subcutaneous injection interface assembly according to arrow 37B of FIG. 37A .

[0075] 38A is an enlarged view of the assembled subcutaneous injection interface assembly according to line 38A of FIG. 35B .

[0076] 38B is a cross-sectional side view of the assembled subcutaneous injection interface assembly of FIG. 38A .

[0077] 38C is a cross-sectional side view of another assembled subcutaneous injection port assembly.

[0078] 38D is a cross-sectional side view of another assembled subcutaneous injection port assembly.

[0079] 38E is a cross-sectional side view of another assembled subcutaneous injection port assembly.

[0080] 38F is a cross-sectional side view of another assembled subcutaneous injection port assembly.

[0081] 39A is a perspective cross-sectional view of a side perspective view of the subcutaneous injection interface assembly according to FIG. 38C , the subcutaneous injection interface assembly being arranged in a rest orientation.

[0082] 39B is another perspective cross-sectional view of the front perspective view of the subcutaneous injection interface assembly according to FIG. 39A , the subcutaneous injection interface assembly being arranged in a biased orientation.

[0083] 39C is another perspective cross-sectional view of the front perspective view of the subcutaneous injection interface assembly according to FIG. 39B , the subcutaneous injection interface assembly being arranged in a disengaged orientation.

[0084] 40 is an illustration of a subcutaneous injection port assembly positioned proximate to an animal.

[0085] 41A is a side view of a subcutaneous injection interface assembly and a cross-sectional view of a portion of the animal of FIG. 40 , the two being arranged in spaced-apart relationship.

[0086] 41B is another side elevational view of the subcutaneous injection port assembly and another cross-sectional view of a portion of the animal according to FIG. 41A , both arranged in a through-hole relationship.

[0087] 41C is another side view of the subcutaneous injection port assembly and another cross-sectional view of a portion of the animal according to FIG. 41B , both arranged in a through-hole relationship while the subcutaneous injection port assembly is optionally used to inject fluid into the animal.

[0088] 41D is another side elevational view of the subcutaneous injection interface assembly and another cross-sectional view of a portion of the animal according to FIG. 41B , both arranged in a through-and-twisted relationship.

[0089] Figure 41E is another side view of the subcutaneous injection interface assembly and another cross-sectional view of a portion of the animal according to Figure 41D, both arranged in a post-piercement separation relationship, defining a first portion of the subcutaneous injection interface assembly attached to the injection gun and a second portion of the subcutaneous injection interface assembly pierced within the skin and flesh of the animal.

[0090] 41F is another side view according to FIG. 41E , showing the user grasping the second portion of the subcutaneous injection port assembly penetrated within the flesh of the animal.

[0091] 41G is another side view according to FIG. 41F , showing the user removing the second portion of the subcutaneous injection port assembly penetrated within the flesh of the animal.

[0092] Corresponding reference characters indicate corresponding parts throughout the drawings. DETAILED DESCRIPTION

[0093] Example configurations will now be described more fully with reference to the accompanying drawings. The example configurations are provided so that this disclosure will be thorough and will fully convey the scope of this disclosure to those of ordinary skill in the art. Specific details, such as examples of specific components, devices, and methods, are set forth to provide a thorough understanding of the configurations of this disclosure. It will be apparent to those of ordinary skill in the art that specific details need not be employed, that the example configurations can be implemented in many different forms, and that the specific details and example configurations should not be construed as limiting the scope of this disclosure.

[0094] The accompanying drawings illustrate exemplary implementations of subcutaneous injection interface assemblies.Based on the foregoing, it should generally be understood that the terminology used herein is for convenience only and should be given the broadest meaning by those of ordinary skill in the art.

[0095] 1 and 33-35B, a subcutaneous injection interface assembly including a cannula 12 (see, e.g., FIGs. 1-2), a needle hub 14 (see, e.g., FIGs. 1 and 3-10), a cannula carrier 100 (see, e.g., FIGs. 18-27H), and an optional adhesive 200 (see, e.g., FIGs. 1 and 31-32) is shown generally at 10. Additionally, a subassembly of the subcutaneous injection interface assembly defined by the cannula 12 and needle hub 14 can be seen in FIGs. 11A-17. A central axis extending through the axial center of each component of the subcutaneous injection interface assembly 10 (e.g., the cannula 12, the needle hub 14, and the cannula carrier 100) is generally indicated by A. 10 -A 10 As will be described in the following disclosure of Figures 31-32, adhesive 200 is radially deposited through radial channels (see, for example, radial channels 122 of cannula carrier 100) and surrounds a portion of cannula 12 for optionally adhesively connecting cannula 12 to at least cannula carrier 100. Thus, central axis A 10 -A 10It may also extend through the axial center of the adhesive after the adhesive 200 is wrapped around the cannula 12. For example, exemplary alternative configurations of the subcutaneous injection interface assembly 10 may also be seen in FIG. 38C and FIG. 39A-39C and function in a similar manner to the subcutaneous injection interface assembly 10.

[0096] As shown in FIG. 40 and FIG. 41A-41G , the cannula 12 is configured to penetrate the outer surface S of a treatment subject S (eg, an animal, such as a human or non-human). S (e.g., skin or hide). Piercing animal skin or hide S The purpose of the injection can be to inject a fluid F (e.g., a drug, a medicine, a vaccine, an anesthetic, etc.) into the body of the animal S, as shown in, for example, FIG. 41C . In other examples, the skin or hide S of the animal S is pierced. S The purpose of the cannula 12 may be to withdraw fluid F (e.g., blood) from the body of the animal S. Accordingly, the cannula 12 may be referred to as a subcutaneous injection cannula, and thus, because the cannula 12 is capable of injecting fluid F into or withdrawing fluid F from the body of the animal S, the assembly 10 may be referred to as a subcutaneous injection port assembly.

[0097] The design of the subcutaneous injection interface assembly 10 provides: (1) a first portion of the subcutaneous injection interface assembly 10 (see, for example, first portion 10a in Figures 37A-37B and Figures 41E-41G) configured to be positioned relative to a central axis A extending through the subcutaneous injection interface assembly 10 when the cannula 12 is subjected to a force relative to a central axis A extending through the subcutaneous injection interface assembly 10; 10 -A 10 One or more radial forces X R and (2) a second portion of the subcutaneous injection interface assembly 10 (see, for example, the second portion 10b at Figures 37A-37B and 41E-41G), which is configured to be inserted into the cannula 12 relative to the central axis A extending through the subcutaneous injection interface assembly 10. 10 -A 10 One or more radial forces X R 39C , in some configurations, the second portion 10b of the subcutaneous injection interface assembly 10 includes the entire length of the cannula 12 (see, for example, L in FIG. 2 ). 12). In some cases, the controlled separation of the second portion 10b of the subcutaneous injection interface assembly 10 from the first portion 10a of the subcutaneous injection interface assembly 10 can occur after the cannula 12 pierces the treatment subject S (see, for example, Figure 40 and Figures 41B-41D). The treatment subject S can be, for example, an animal, such as a human or a non-human (i.e., an animal such as a pig). In other examples, the treatment subject S can be an inanimate object. The predictable and controlled separation of the second portion 10b of the subcutaneous injection interface assembly 10 from the first portion 10a of the subcutaneous injection interface assembly 10 mitigates the separation of the cannula 12 from the needle hub 14 alone, which could otherwise cause the cannula 12 to break from the injection gun 1 and subsequently be lost in the animal's flesh.

[0098] As shown in FIG. 2 , the cannula 12 comprises a proximal end 16 P and remote 16 D The cannula 12 is defined by a tubular body 16. The cannula 12 is formed by a proximal end 16 of the tubular body 16. P and the distal end 16 of the tubular body 16 D The length L between 12 The length L of the sleeve 12 is limited. 12 By multiple sub-lengths L 12a (including the sub-length part L 12a1 、L 12a2 、L 12a3 and L 12a4 ), L 12b and L 12c Definitions, which will be further described in the disclosure text below.

[0099] The sleeve 12 can be formed using any desired manufacturing process, such as drawing, molding, casting, machining, lathing, or a combination thereof. The sleeve 12 can be made of any desired material, such as a metal, a plastic, or a combination thereof. In some examples, the sleeve 12 can be made of stainless steel. In other cases, the sleeve 12 can be made of aluminum. In other examples, the sleeve 12 can be made of a detectable material, such as a detectable alloy, a ferromagnetic alloy, a magnetically detectable material, a magnetic resonance imaging (MRI) detectable material, an X-ray absorbing material, or the like.

[0100] The cannula 12 can be defined according to a "gauge size" that takes into account the thickness of the skin / hide of the subject S and / or the injection depth of the subject S. The gauge size of the cannula 12 can be defined in a series of industry-standard numbers, where, for example, the lower the number, the wider the diameter of the cannula. Furthermore, the industry-standard numerical series defining the gauge size of the cannula 12 can be defined in such a way that, for example, higher gauge numbers indicate a smaller width of the cannula 12. In some cases, the industry-standard gauge sizes of the cannula 12 can be, for example, 14 gauge; 16 gauge; 18 gauge; and 20 gauge. Thus, within the range of the aforementioned exemplary industry-standard numbers, a 14 gauge cannula can be said to have the relatively largest diameter and the highest strength (in terms of bendability / flexibility at the point where the cannula 12 may break / fail), while a 20 gauge cannula can be said to have the relatively smallest diameter and the lowest strength (in terms of bendability / flexibility at the point where the cannula 12 may break / fail).

[0101] Central axis A 12 -A 12 The longitudinal axis L of the tubular body 16 is passed through the axial center of the tubular body 16 and along the length L of the tubular body 16. 12 As will be described in the following disclosure and shown in FIG. 41D and FIG. 2 , the length L of the tubular body 16 is 12 A portion of (see, for example, the sub-length portion L 12c ) can bend, flex or deviate from the central axis A extending through the axial center of the tubular body 16 12 -A 12 The length L of the tubular body 16 12 The sub-length part L 12c Can bend, flex or deviate from the central axis A 12 -A 12 , roughly along axis A 12 '-A 12 'Extension, when the cannula 12 is arranged as a component of the subcutaneous injection interface assembly 10, it can be said that the axis is not aligned with the central axis A passing through the subcutaneous injection interface assembly 10 10 -A 10 aligned with and offset from this central axis.

[0102] The tubular body 16 is further formed by a proximal end 16 of the tubular body 16 P The proximal end surface 18 and the distal end 16 of the tubular body 16 D1 and 2. The tubular body 16 is further defined by an outer surface 22 extending between the proximal surface 18 and the distal surface 20. The tubular body 16 is further defined by an inner surface 24 extending between the proximal surface 18 and the distal surface 20. The inner surface 24 further defines a passage 26 extending through the tubular body 16. The proximal surface 18 defines a proximal opening 28 in fluid communication with the passage 26. The distal surface 20 defines a distal opening 30 in fluid communication with the passage 26.

[0103] 38A (which shows an enlarged cross-sectional view of an exemplary subcutaneous injection interface assembly 10), the body 16 of the cannula 12 is formed by a thickness T extending between the outer surface 22 of the body 16 and the inner surface 24 of the body 16. 12 The outer surface 22 further defines the outer diameter D of the sleeve 12. 12 , the outer diameter is based on the center axis A 12 -A 12 As a reference, the central axis can be aligned with the corresponding central axis A of each of the subcutaneous injection interface assembly 10 and the needle hub 14. 10 -A 10 and A 14 -A 14 The inner surface 24 further defines a channel 26 having a channel diameter D 26 The passageway 26 is in fluid communication with the proximal opening 28 and the distal opening 30 to allow: (1) fluid F (see, e.g., FIG. 41C ) to enter the tubular body 16 at the proximal opening 28; and (2) fluid F to flow from the proximal end 16 of the tubular body 16. P Towards the distal end 16 of the tubular body 16 D and (3) out of the distal opening 30.

[0104] 2 and 38A, the proximal surface 18 extends substantially perpendicularly from the outer surface 22 and is thus defined as being blunt or non-sharp. In addition, the proximal opening 28 formed by the proximal surface 18 may be defined by a channel diameter D that is substantially perpendicular to the channel 26. 26 Basically similar proximal opening diameter D 28 A defined basic circular geometric shape.

[0105] 2 , the distal surface 20 is inclined at an angle θ 20 Extending from the outer surface 22, the distal surface 20 can therefore be referred to as an inclined distal surface that terminates in or defines a sharp piercing tip 32. The inclined distal surface 20 can be formed by any desired bevel angle θ, such as a "standard bevel," a "short bevel," or a "true short bevel." 20 Because the inclined distal surface 20 is inclined at an angle θ 20Extending from the outer surface 22, the distal opening 30 can be defined by an elliptical geometry. In one embodiment, the distal surface 20 can be defined by three separate beveled cuts.

[0106] As shown in FIG3-10 , the needle hub 14 comprises a proximal end 34 P and remote 34 D The needle hub 14 is defined by a generally tubular body 34. The needle hub 14 is formed by a proximal end 34 of the generally tubular body 34. P and a distal end 34 of the generally tubular body 34 D The length L between 14 (See, for example, FIG. 7 ) The length L of the needle hub 14 is defined. 14 By multiple sub-lengths L 14a 、L 14b 、L 14c and L 14d Definitions, which will be further described in the disclosure text below.

[0107] The needle hub 14 can be formed using any desired manufacturing process, such as: a molding process; a casting process; a machining process; a lathe process; or a combination thereof. The needle hub 14 is made of any desired material, such as: a metal material; a plastic material; or a combination thereof. In some examples, the needle hub 14 can be made of a stainless steel material. In other cases, the needle hub 14 can be made of an aluminum material, brass, steel, or an alloy. In other examples, the needle hub 14 can be made of a plastic material, including but not limited to polypropylene (PP), polyethylene terephthalate (PET), polyamide (such as nylon 6, nylon 66, thermosetting plastics such as polyester resin, epoxy resin, acrylic resin), etc. In addition, in some cases, the needle hub 14 can be finished with anodizing, polishing, electropolishing, coating, paint, etc., such as having a highly visible finish (e.g., dye, fluorescent coating, phosphorescent coating, bright gloss, matte color finish, or preferably a flesh color or surface S that is not similar to animal skin or flesh). S analogues of the colour of ).

[0108] The generally tubular body 34 is further formed by a proximal end 34 of the generally tubular body 34. P The proximal end surface 36 and the distal end 34 of the generally tubular body 34 D The generally tubular body 34 is further defined by an outer surface 40 extending between the proximal and distal end surfaces 36, 38. The generally tubular body 34 is further defined by an inner surface 42 extending between the proximal and distal end surfaces 36, 38.

[0109] The inner surface 42 further defines a passage 44 extending through the generally tubular body 34. The proximal surface 36 defines a proximal opening 46 (see, e.g., Figs. 4, 7, and 10) that is in fluid communication with the passage 44. The distal surface 38 defines a distal opening 48 (see, e.g., Figs. 3, 5, 7, 8B, 9B) that is in fluid communication with the passage 44.

[0110] As shown in FIG3-10 , the annular portion 50 is away from the central axis A. 14 -A 14 The annular portion 50 projects radially outwardly away from the outer surface 40 of the generally tubular body 34. The annular portion 50 may alternatively be referred to as a barrel engaging portion, which is configured to be connected to the barrel portion 1 of the injection gun 1. B (See, e.g., FIG. 40 .) The barrel engaging portion 50 is defined by an outer side surface 52 extending between the proximal end surface 36 and the distal shoulder surface 54. The barrel engaging portion 50 may be formed by a thickness T extending between the proximal end surface 36 and the distal shoulder surface 54. 50 (See, eg, Figures 6 and 7) The barrel engaging portion 50 may generally define a Luer lock.

[0111] The outer surface 40 of the generally tubular body 34 can define a generally circular geometry that defines a first outer diameter D of the needle hub 14. 14-1 (See, eg, FIG. 7 .) The outer side surface 52 of the barrel engaging portion 50 can define a generally circular geometry that defines a second outer diameter D of the needle hub 14 . 14-2 (See, for example, FIG. 7 .) The second outer diameter D of the needle hub 14 14-2 Greater than the first outer diameter D of the needle seat 14 14-1 The outer surface 40 of the generally tubular body 34 may further define another generally circular geometry that further defines a third outer diameter D of the needle hub 14 . 14-3 (See, e.g., FIG. 7 ).

[0112] 3-5, 8A-8B, 9A-9B and 10, the substantially circular geometry of the outer side surface 52 of the barrel engagement portion 50 is extended beyond the second outer diameter D of the needle hub 14. 14-2 The first radially outward protrusion or ear 56 is interrupted by the second radially outward protrusion or ear 58. The first radially outward protrusion or ear 56 can be arranged opposite or offset from the second radially outward protrusion or ear 58 by about 180°.

[0113] As shown in FIG7 , the inner surface 42 of the generally tubular body 34 includes a first inner surface portion 42a, a second inner surface portion 42b, and a third inner surface portion 42c. Each of the first inner surface portion 42a and the second inner surface portion 42b generally defines the central axis A of the needle hub 14. 14-A 14 The third inner surface portion 42c connects the first inner surface portion 42a to the second inner surface portion 42b; in addition, the third inner surface portion 42c can be aligned with the central axis A of the needle seat 14. 14 -A 14 The third inner surface portion 42c can be substantially perpendicular to each of the first inner surface portion 42a and the second inner surface portion 42b; in some implementations, the transition of each of the first inner surface portion 42a and the second inner surface portion 42b to the third inner surface portion 42c can be defined by a curved or arcuate segment. As will be seen in the following disclosure of Figures 11B-11C, after at least a portion of material is deformed, such as the second portion 34b of the generally tubular body 34 of the needle hub 14 (e.g., by crimping a portion of the second portion 34b of the generally tubular body 34 of the needle hub 14 after the cannula 12 is docked with the needle hub 14, as shown in Figure 11B), the curved or arcuate segment connecting the second inner surface portion 42b to the third inner surface portion 42c can change shape due to material movement or "flow" such that a portion of the third inner surface portion 42c extending from the second inner surface portion 42b can define a frustoconical surface portion surrounding the cannula 12 (see, e.g., Figure 11C).

[0114] The first inner surface portion 42a of the inner surface defines a first channel portion 44a of the channel 44. The second inner surface portion 42b defines a second channel portion 44b of the channel 44.

[0115] The first channel portion 44a defines a first channel diameter D of the channel 44. 44-1 (See, eg, FIG. 7 .) The second channel portion 44b defines a second channel diameter D of the channel 44. 44-2 (See, for example, FIG. 7 ). First channel diameter D 44-1 Larger than the second channel diameter D 44-2 The second channel diameter D 44-2 Roughly equal to but slightly larger than the outer diameter D of the sleeve 12 12 .

[0116] The first channel portion 44a of the channel 44 is in fluid communication with the proximal opening 46, and the second channel portion 44b of the channel 44 is in fluid communication with the distal opening 48. In addition, the first channel portion 44a is in fluid communication with the second channel portion 44b via the intermediate opening 47. Thus, the channel 44 allows: (1) fluid F (see, e.g., FIG. 41C ) to enter the generally tubular body 34 at the proximal opening 46; (2) fluid F to flow from the proximal end 34 of the generally tubular body 34 to the distal end 34. Pand passing through the first channel portion 44a of the channel 44 toward the intermediate opening 47 defined by the third inner surface portion 42c; (3) passing through the intermediate opening 47 of the proximal opening of the second channel portion 44b defining the channel 44; (4) along the path from the intermediate opening 47 toward the distal end 34 of the generally tubular body 34. D and (5) flows out from the distal opening 48.

[0117] The proximal opening 46 formed by the proximal end surface 36 may be defined by a proximal opening diameter D 46 (See, e.g., FIG. 7 ) defining a substantially circular geometry, the proximal opening having a diameter substantially similar to the first channel diameter D of the first channel portion 44 a. 44-1 The intermediate opening 47 formed by the third inner surface portion 42c of the inner surface 42 of the generally tubular body 34 may be defined by a diameter substantially equal to the second passage diameter D 44-2 The middle opening diameter D 47 (See, for example, FIG. 7 ) The distal opening 48 formed by the distal end surface 38 may be defined by a substantially circular geometry substantially similar to the second passageway diameter D 44-2 The distal opening diameter D 48 (See, e.g., FIG. 7 ) for a substantially circular geometry defined by the first channel portion 44a. Although some of the dimensions / diameters / geometries described above are substantially similar or identical, the views of the needle hub 14 in the figures (e.g., in FIG. 7 ) are illustrative and not drawn to scale. In some cases, the first channel portion 44a can be formed to include a draft angle (e.g., a 1° draft angle) that can, for example, aid in removing the needle hub 14 from a tool when forming the needle hub 14. Thus, as the first channel diameter D of the first channel portion 44a increases, the first channel diameter D of the first channel portion 44a decreases. 44-1 The first channel portion 44a has a first channel diameter D extending in a direction from the proximal end surface 36 of the needle hub 14 toward the distal end surface 38 of the needle hub 14. 44-1 The diameter can be gradually reduced.

[0118] 3-6, 8A, 8B, 9A and 9B, one or more ribs 60 may be away from the central axis A. 14 -A 14 Projecting radially outwardly away from an outer body surface portion 62 defined by the outer surface 40 of the generally tubular body 34. The one or more ribs 60 may include, for example, a first rib 60a, a second rib 60b, a third rib 60c, and a fourth rib 60d.

[0119] One or more ribs 60 can increase the structural integrity of the generally tubular body 34 of the needle hub 14. In some configurations, the one or more ribs 60 can be generated by mold decompression features during the manufacturing process of the generally tubular body 34 of the needle hub 14. In addition, the one or more ribs 60 can be configured to engage packaging (not shown). The engagement of the one or more ribs 60 with the packaging can help contain the cannula 12 and needle hub 14 during shipping and / or facilitate engagement / disengagement of the needle hub 14 with the injection gun 1. As shown throughout the figures, an outer surface portion of each rib 60a, 60b, 60c, 60d can extend radially outward to define a lug portion; the lug portion can be defined, for example, by an inclined surface or ramp 61. Each lug portion can be sized to engage with the packaging.

[0120] Each of the one or more ribs 60a, 60b, 60c, 60d includes a distal end 60 D and proximal 60 P The proximal end 60 of each rib 60a, 60b, 60c, 60d of the one or more ribs 60 P Extending from the distal shoulder surface 54 of the barrel engaging portion 50. The distal end 60 of each of the one or more ribs 60a, 60b, 60c, 60d D The one or more ribs 60 may extend in a direction toward the distal end surface 38 of the generally tubular body 34 and terminate at, before, or near an outer shoulder surface portion 64 (see, e.g., FIGs. 3-9 ) defined by the outer surface 40 of the generally tubular body 34. Each rib 60a, 60b, 60c, 60d of the one or more ribs 60 may define a generally rectangular body terminating at a distal end 60 of each rib 60a, 60b, 60c, 60d of the one or more ribs 60. D The main part of the basic triangle is defined.

[0121] The outer shoulder surface portion 64 extends from a distal-most end of the outer body surface portion 62 of the outer surface 40 of the generally tubular body 34. In some configurations, the outer shoulder surface portion 64 can define a dome-shaped or curved outer shoulder surface portion.

[0122] 3-7, 8A and 9A, the distal end of the outer shoulder surface portion 64 terminates in an outer head surface portion 68. The outer head surface portion 68 generally surrounds the central axis A of the needle hub 14. 14 -A 14 Draw a circle.

[0123] As shown in FIG. 7 , the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 defines a third outer diameter D of the needle hub 14 . 14-3 As shown in Figure 7, the second outer diameter D 14-2 Greater than the third outer diameter D 14-3 .

[0124] 6-7, the subcutaneous injection interface assembly 10 also includes a circumferential recess or groove 65 that is configured to receive one or more portions of the cannula carrier 100 (see, e.g., FIGs. 28-30). The circumferential recess or groove 65 can extend into the outer body surface portion 62 of the outer surface 40 of the generally tubular body 34 of the needle hub 14, a distance away from the distal end surface 38 of the needle hub 14 (see, e.g., sub-length L). 14a In some configurations, a circumferential notch or groove 65 can extend into the outer surface 40 of the generally tubular body 34 near a proximal end of the outer shoulder surface portion 64. The circumferential notch or groove 65 can be defined by a plurality of surface portions (see, e.g., surface portions 65a, 65b, 65c, 65d in FIG. 29 ) of the outer surface 40 of the generally tubular body 34. The surface portions 65a, 65b, 65c, 65d defining the circumferential notch or groove 65 can be shaped to matingly receive one or more corresponding surface portions of the cannula carrier 100 (see, e.g., barbed surface portions 130a, 130b, 130c, 130d).

[0125] 7, the sub-length L 14a The length of the outer shoulder surface portion 64 and the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 is defined. 14b A length circumferential notch or groove 65 is defined by an outer body surface portion 62 of the outer surface 40 of the generally tubular body 34. Sub-length L 14c The length of the outer body surface portion 62 of the outer surface 40 of the generally tubular body 34 is defined, extending between the proximal end of the circumferential notch or groove 65 and the distal shoulder surface 54 of the barrel engaging portion 50. 14d A thickness of the barrel engaging portion 50 is defined that extends between the proximal end surface 36 of the generally tubular body 34 and the distal shoulder surface 54 of the barrel engaging portion 50 .

[0126] As will be described in the following disclosure, the generally tubular body 34 of the needle hub 14 may define a first portion 10a of the subcutaneous injection interface assembly 10, which is configured to be inserted into the subcutaneous injection interface assembly 10 when the cannula 12 is subjected to a pressure relative to a central axis A extending through the subcutaneous injection interface assembly 10. 10 -A 10 One or more radial forces X RThereafter, it remains attached to the injection gun 1. The cannula carrier 100 (which is removably connected to the needle hub 14, for example, by a circumferential recess or groove 65 defined by the outer body surface portion 62 of the outer surface 40 of the generally tubular body 34 of the needle hub 14) can define a first component portion of the second portion 10b of the subcutaneous injection interface assembly 10 (the second component portion of the second portion 10b of the subcutaneous injection interface assembly 10 being the cannula 12 and the third component being the optional adhesive 200) that is configured to be attached to the cannula 12 when the cannula 12 is subjected to an applied force relative to a central axis A extending through the subcutaneous injection interface assembly 10. 10 -A 10 One or more radial forces X R 41G ) from the flesh of the animal S, so that the cannula 12 is not lost in the flesh of the animal S (if it is not moved relative to the central axis A extending through the subcutaneous injection interface assembly 10 during use of the subcutaneous injection interface assembly 10). 10 -A 10 One or more radial forces X R is applied to the cannula 12, which might otherwise undesirably cause the cannula 12 to separate from the injection gun 1).

[0127] 11A-11C , a method for assembling a subassembly (defined by cannula 12 and needle hub 14) of subcutaneous injection interface assembly 10 (the subassembly of which is shown in assembled form in FIGS. 12-17 , 28 , and 29 ) is described. First, in FIG. 11A , the components (i.e., cannula 12 and needle hub 14 of the subassembly) are positioned about a central axis A. 10 -A 10 Axial alignment (see also Figure 1). Central axis A 10 -A 10 Corresponding to, for example, the central axis A of each of the cannula 12 and the needle hub 14 12 -A 12 、A 14 -A 14 .

[0128] As will be described in the following disclosure, the cannula 12 is mechanically coupled to any portion of the needle hub 14 due to material deformation of, for example, at least a portion of the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14 (e.g., by crimping, for example, a portion of the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14, as shown in Figures 11B and 11C). Although the subassemblies of the subcutaneous injection interface assembly 10 are formed by mechanical connection, the cannula 12 may alternatively or additionally be coupled to any portion of the needle hub 14, for example, with an adhesive (not shown), such as an acrylic adhesive, a cyanoacrylate adhesive, an ultraviolet (UV) curable adhesive, etc. In other configurations, the needle hub 14 may be attached to the cannula 12 by overmolding the material defining the needle hub 14 relative to the cannula 12 (e.g., when the needle hub 14 is formed of a moldable material such as a plastic material).

[0129] As shown in FIG. 11A , a portion of the cannula 12 includes a proximal end 16 of the tubular body 16. P The proximal end surface 18 at the cannula 12 is shown disposed adjacent a distal opening 48 formed by the distal end surface 38 of the needle hub 14 (which is in fluid communication with the second channel portion 44b of the channel 44 of the needle hub 14). 12 -A 12 (See, for example, FIG. 2 ) and the central axis A of the needle hub 14 14 -A 14 Axial alignment. The central axis A of each of the cannula 12 and the needle hub 14 12 -A 12 and A 14 -A 14 Corresponding to the central axis A of the subcutaneous injection interface assembly 10 10 -A 10 (See Figure 1).

[0130] As mentioned above, the outer surface 22 of the tubular body 16 of the sleeve 12 defines the outer diameter D of the sleeve 12. 12 , and the second channel diameter D 44-2 The second channel portion 44b (defining the channel 44) is approximately equal to but slightly larger than the outer diameter D of the sleeve 12. 12 , so that at least a portion of the second channel portion 44b of the channel 44 is configured to receive the cannula 12. Then, as shown in Figures 11B-11C, the proximal end 16 of the tubular body 16 of the cannula 12 PThe cannula 12 is inserted (according to the direction of arrow Y as shown in FIG. 11A ) through the distal opening 48 formed by the distal end surface 38 of the needle hub 14 and then disposed within at least a portion of the second channel portion 44 b of the channel 44 of the needle hub 14. In some configurations, such as those shown in FIG. 11C and FIG. 38A-38B , the cannula 12 can be arranged relative to the needle hub 14 such that the proximal end 16 of the tubular body 16 of the cannula 12 is P The cannula 12 is positioned outside the third inner surface portion 42c (see, for example, dashed line P1 in FIG. 38B ) of the inner surface 42 of the generally tubular body 34. Thus, a portion of the cannula 12 is disposed within and completely occupies the second channel portion 44b of the channel 44 of the needle hub 14, while also being partially disposed within the first channel portion 44a of the channel 44 of the needle hub 14.

[0131] 11B , the cannula 12 is disposed within the passage 44 of the needle hub 14 and mechanically coupled to the needle hub 14, for example, by disposing the head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14 within, for example, a crimping tool T. The crimping tool T may stamp, crimp, mold, or materially deform, for example, all or a portion of the head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14 to mechanically couple all or a portion of the second inner surface portion 42 b of the inner surface 42 of the generally tubular body 34 of the needle hub 14 to a portion of the length (see, for example, sub-length L) of the outer surface 22 of the tubular body 16 of the cannula 12 in a friction fit, interference fit, or mechanical coupling relationship. 12a2 in Figure 2).

[0132] 11C , the cannula 12 can be mechanically coupled to the needle hub 14 due to material deformation of a portion of the needle hub 14 by the crimping tool T. In some configurations shown in FIG11C and FIG12 , as well as in FIG15-17 and FIG28 , the crimping tool T can stamp, crimp, mold, or otherwise materially deform a portion of, for example, the outer surface 40 of the generally tubular body 34. In some implementations, for example, the crimping tool T can stamp, crimp, mold, or otherwise materially deform a portion of, for example, the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 (e.g., see reference numeral 68 ′). Thus, in such an implementation, the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 may define a crimping pocket (see, e.g., numeral 68'), which represents material deformation of the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 and thereby distinguishes a "deformed" hub 14 that is mechanically coupled to the cannula 12 from an original or "undeformed" hub 14 (e.g., see FIG. 3-10 ), which has an outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 that does not define the crimping pocket 68'.

[0133] As described above, a portion of the length (e.g., a sub-length L) of the outer surface 22 of the tubular body 16 of the cannula 12 12a2 ) can be disposed within the second channel portion 44b of the channel 44 of the needle hub 14 and can be mechanically secured (see, e.g., FIG. 11C ) to at least a portion of the second inner surface portion 42b of the inner surface 42 of the generally tubular body 34 of the needle hub 14, which can extend along a length L of the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14. 14a (See, e.g., FIG. 7 ) for a sub-length of the needle hub 14 defined. Additionally, with reference to FIG. 11C and 38A , another portion of the length of the outer surface 22 of the tubular body 16 of the cannula 12 (e.g., the sub-length L in FIG. 2 ) may be defined as a portion of the length of the needle hub 14 defined as a sub-length ... 12a3 ) can be disposed within the second channel portion 44b of the channel 44 of the needle hub 14 and can extend along the length L of the head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14. 14a Thus, in some implementations, the length L of the needle hub 14 may extend to a sub-length of the needle hub 14. 14 The sub-length L 14a A portion of the sleeve 12 may not be subjected to material deformation by the crimping tool T. For example, the sub-length L of the sleeve 12 12a3 The sub-length L of the head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14 may not be along 14a The portion is mechanically coupled to the needle hub 14 .

[0134] 11C and 38A, a portion of the length of the outer surface 22 of the tubular body 16 of the cannula 12 (see, for example, the length portion L 12a4 ) can be disposed within the second channel portion 44b of the channel 44 of the needle hub 14, which can be along the length L of the outer shoulder surface portion 64 of the outer surface 40 of the generally tubular body 34 of the needle hub 14. 14a 2, 11C and 38A, the remaining portion / length of the outer surface 22 of the tubular body 16 of the cannula 12 (see, for example, the length portion L 12c ) extends beyond the distal surface 38 of the needle hub 14 and is not contained within the channel 44 of the needle hub 14.

[0135] 28-32 , in addition to cannula 12 being coupled to needle hub 14 to define a subassembly (defined by cannula 12 and needle hub 14), the subassembly can be coupled to cannula carrier 100 to further define subcutaneous injection interface assembly 10 (and adhesive 200 can be deposited and subsequently cured). Subcutaneous injection interface assembly 10 can be coupled to injection gun 1 (see, e.g., FIG. 40 ). As described below in the disclosure of FIG. 41A-41G , second portion 10b of subcutaneous injection interface assembly 10 is configured to controllably separate from first portion 10a of subcutaneous injection interface assembly 10 (see, e.g., FIG. 35A-35B , FIG. 36A-36B , and FIG. 37A-37B ). Referring to FIG. 18-27H , an exemplary cannula carrier 100 will now be described.

[0136] 18-21, an exemplary cannula carrier 100 includes a head 102 and a plurality of legs 104 defined by, for example, four legs, including a first leg 104a (see, for example, FIG. 19), a second leg 104b (see, for example, FIG. 18), a third leg 104c (see, for example, FIG. 21), and a fourth leg 104d (see, for example, FIG. 20). The head 102 includes a body 106 extending between a proximal surface 108 and a distal surface 110. The body 106 is further defined by a thickness T extending between an inner surface 112 (see, for example, FIG. 29) and an outer surface 114. 106 (See, for example, FIG. 29 ) as defined. The cannula carrier 100 can be formed using any desired manufacturing process, such as a molding process; a casting process; a machining process; or a combination thereof. The cannula carrier 100 can be made of any desired material, such as a metal material; a plastic material; or a combination thereof. In some embodiments, the cannula carrier 100 can be made of a high-visibility dye or pigment, such as a bright color pigment, a fluorescent pigment, a phosphorescent pigment, a retroreflective partially mirrored glass bead, a metallic flake pigment, etc., which preferably matches the flesh color or surface S of the animal hide or flesh. SAdditionally, when the ferrule carrier 100 is formed, the ferrule carrier 100 may include an overmolded RFID component (not shown) embedded in the material or an RFID sticker (not shown) or other identifying information disposed on one or more of the inner and outer surfaces 112, 114 of the ferrule carrier 100 to facilitate determining a location and / or serial number or other identification associated with the ferrule carrier 100.

[0137] 29 , the inner surface 112 of the body 106 of the head 102 of the cannula carrier 100 defines an axial passage 116. Access to the axial passage 116 is provided by a proximal opening 118 (e.g., see FIGS. 22 , 25 , and 27A-27H ) and a distal opening 120 (e.g., see FIGS. 18-21 , 23 , and 24 ). Furthermore, the inner surface 112 includes a first inner surface portion 112a defining a first channel portion 116a. The inner surface 112 also includes a second inner surface portion 112b defining a second channel portion 116b in fluid communication with the first channel portion 116a. The first inner surface portion 112a extends from the proximal surface 108 and defines a proximal opening 118. The second inner surface portion 112b extends from the distal surface 110 and defines a distal opening 120.

[0138] The first channel portion 116a is formed by a first channel diameter D 116a Defined (see, for example, FIG. 29 ), the second channel portion 116 b is defined by a second channel diameter D 116b Defined (see, for example, FIG. 29 ). The first channel diameter D 116a Larger than the second channel diameter D 116b The second channel diameter D 116b Approximately equal to but slightly larger than the outer diameter D of the sleeve 12 12 , such that at least a portion of the second channel portion 116b defined by the second inner surface portion 112b of the inner surface 112 of the body 106 of the head 102 of the cannula carrier 100 is configured to receive the cannula 12. As described below in the disclosure of Figures 28-31, when the cannula 12 is disposed within the second channel portion 116b, the length L of the cannula 12 is 12 Part L 12a1 (See FIG2 ) may be disposed within the second channel portion 116 b of the head portion 102 of the cannula carrier 100 such that the outer surface 22 of the tubular body 16 of the cannula 12 may be friction fit coupled to the second inner surface portion 112 b of the inner surface 112 of the body 106 of the head portion 102 of the cannula carrier 100 so as to “plug” or “fluid seal” the distal opening 120 of the cannula carrier (100).

[0139] 18-20, 22, 23, 26A-26C, and 26G-26H, the body 106 of the head 102 of the ferrule carrier 100 further defines a radial passage 122 extending through the thickness T of the body 106 of the head 100 of the ferrule carrier. 106 As shown in FIG29 , access to the radial passage 122 is provided by an inner surface opening 124 defined by the inner first inner surface portion 112 a of the inner surface 112 of the body 106 of the ferrule carrier 100 (i.e., the radial passage 122 is in direct fluid communication with the first channel portion 116 a). Referring to any of FIG18-20 , FIG22 , FIG23 , FIG26A-26C , and FIG26G-26H , access to the radial passage 122 is also provided by an outer surface opening 126 defined by the outer surface 114 of the body 106 of the head 102 of the ferrule carrier 100. For example, as shown in FIG19 , the radial passage 122 can be axially aligned with a leg 104 (e.g., a first leg 104 a of the plurality of legs 104) of the ferrule carrier 100.

[0140] Each leg 104a, 104b, 104c, 104d extends axially from the proximal surface 108 of the body 106 of the head 102 of the cannula carrier 100. Collectively, the legs 104a, 104b, 104c, 104d extend about a central axis A extending through the axial center of the cannula carrier 100. 100 -A 100 , and each leg may be circumferentially offset by approximately 90° from an adjacent leg 104a, 104b, 104c, 104d, defining an axial gap 128 between each adjacent leg 104a, 104b, 104c, 104d.

[0141] 18-23 , each leg 104a, 104b, 104c, 104d is defined by a proximal barb portion 130. As shown in FIG29 , each proximal barb portion 130 is defined by a plurality of barbed surface portions 130a, 130b, 130c, 130d that can be configured to mate with surface portions 65a, 65b, 65c, 65d defining a circumferential notch or groove 65 in an outer body surface portion 62 extending into the outer surface 40 of the generally tubular body 34 of the needle hub 14. Each leg 104a, 104b, 104c, 104d can extend in the proximal direction beyond each barb surface portion 130a, 130b, 130c, 130d such that each leg 104a, 104b, 104c, 104d provides additional engagement with each rib 60a, 60b, 60c, 60d to transmit torque between the needle carrier 100 and the needle hub 14 (e.g., to engage and disengage the Luer lock mechanism).

[0142] As shown in FIG. 28 and FIG. 29 , a portion of the cannula 12 includes a proximal end 16 of the tubular body 16. P The proximal end surface 18 of the cannula 12 is shown disposed adjacent the distal opening 120 formed by the distal end surface 110 of the body 106 of the head 102 of the cannula carrier 100. The central axis A of the cannula 12 12 -A 12 (See, for example, FIG. 2 ) and the central axis A of the casing carrier 100 100 -A 100 Axial alignment. The central axis A of each of the ferrule 12 and the ferrule carrier 100 12 -A 12 and A 100 -A 100 Corresponding to the central axis A of the subcutaneous injection interface assembly 10 10 -A 10 (See Figure 1).

[0143] As mentioned above, the outer surface 22 of the tubular body 16 of the sleeve 12 defines the outer diameter D of the sleeve 12. 12 , and defines a second channel diameter D of the second channel portion 116b of the channel 116 116b Approximately equal to but slightly larger than the outer diameter D of the sleeve 12 12 , such that at least a portion of the second channel portion 116b of the channel 116 defined by the body 106 of the cannula 12 configured to receive the cannula 12 can result in the length L of the tubular body 16 of the cannula 12 12 Part L 12a1 "plugging" or "fluid sealing" the distal opening 120 of the cannula carrier 100. Thus, as shown in Figures 29-30, the distal end 16 of the tubular body 16 of the cannula 12 D 29 ) and enters the first channel portion 116 a of the channel 116 for subsequent placement in the second channel portion 116 b of the channel 116.

[0144] Thereafter, the distal end 16 of the tubular body 16 of the cannula 12 D Inserted through the distal opening 120 of the cannula carrier 100, such that the length L of the tubular body 16 of the cannula 12 12 Part of L 12c10 extends beyond the distal end surface 110 of the body 106 of the head 102 of the cannula carrier 100. Advancement of the tubular body 16 of the cannula 12 continues through the distal opening 120 of the cannula carrier 100 until the proximal barb portion 130 of each leg 104a, 104b, 104c, 104d of the plurality of legs 104 slides over and flexes against the outer shoulder surface portion 64 of the outer surface 40 of the generally tubular body 34 of the needle hub 14, then slides past and then flexes into the circumferential notch or groove 65 for subsequent registration. Once each leg 104a, 104b, 104c, 104d of the plurality of legs 104 is aligned within the circumferential notch or groove 65, the plurality of barbed surface portions 130a, 130b, 130c, 130d of each proximal barb portion 130 of each leg 104a, 104b, 104c, 104d of the plurality of legs 104 are positioned adjacent to and matingly coupled with the surface portions 65a, 65b, 65c, 65d defining the circumferential notch or groove 65 to mechanically couple the cannula carrier 100 to the needle hub 14.

[0145] 31 , after the cannula carrier 100 is mechanically coupled to the needle hub 14, a quantity of adhesive 200 is disposed within the first channel portion 116a of the channel 116 defined by the body 106 of the cannula carrier 100 for non-removably coupling the cannula 12 to the cannula carrier 100. The adhesive 200 may be applied to the cannula 12 by extending through the thickness T of the body 106 at the head of the cannula carrier 100. 106 The radial channel 122 is deposited or injected into the first channel portion 116a of the channel 116 defined by the body 106 of the ferrule carrier 100. In some cases, the radial channel 122 can be sized to receive the nozzle of an adhesive applicator A (as shown in FIG31). Although the ferrule carrier 100 is described above as being adhesively connected to the ferrule 12 using an adhesive 200, the ferrule 100 can alternatively and / or additionally be mechanically connected to the ferrule 12 by a material deformation process, such as associated with swaging, crimping, welding, etc. Exemplary welding processes can include electron beam welding, ultrasonic welding, etc.

[0146] 32 , adhesive 200 may fill at least a portion or all of first channel portion 116a of channel 116 defined by body 106 of ferrule carrier 100. In other configurations, adhesive 200 may also fill at least a portion or all of radial channel 122.

[0147] Once the desired amount of adhesive 200 is deposited into the first channel portion 116a, the adhesive 200 may be disposed about and adjacent to: (1) a length L defined by the outer surface 22 of the tubular body 16 of the cannula 12 disposed within the first channel portion 116a; 12 Part L12a1 ; and (2) at least a portion of the first inner surface portion 112a, which defines a first channel portion 116a for non-removably and adhesively attaching the cannula 12 to the cannula carrier 100. In some configurations, the adhesive 200 is an acrylic adhesive, a cyanoacrylate adhesive, an ultraviolet (UV) curable adhesive, or the like. As shown in FIG32 , if the adhesive 200 is a UV curable adhesive, ultraviolet light (UV) can be directed toward the adhesive 200 using a UV light source (not shown) to cure the adhesive 200. Once the adhesive 200 has cured, the subcutaneous injection interface assembly 10 can be said to be in the form shown in FIGS. 33-35B .

[0148] Although the exemplary design of the subcutaneous injection interface assembly 10 utilizes both: (1) the proximal barb portion 130 of each leg 104a, 104b, 104c, 104d to mechanically couple the cannula carrier 100 to the needle hub 14; and (2) the adhesive 200 for bonding the cannula carrier 100 to the cannula 12, some implementations of the subcutaneous injection interface assembly 10 may include one of a mechanical coupling and / or an adhesive coupling. For example, the subcutaneous injection interface assembly 10 may be mechanically coupled solely by frictionally coupling the cannula 12 to the cannula carrier 100 (i.e., the adhesive 200 may be excluded from this exemplary implementation of the subcutaneous injection interface assembly) and the proximal barb portion 130 of each leg 104a, 104b, 104c, 104d.

[0149] 34 and 35A-35B, the subcutaneous injection interface assembly 10 is shown in a rest orientation. In FIG36A-36B, the subcutaneous injection interface assembly 10 is shown in a biased orientation. Thereafter, as shown in FIG37A-37B, the subcutaneous injection interface assembly 10 is shown arranged in a separated orientation defined by a first portion 10a of the subcutaneous injection interface assembly 10 configured to remain attached to the injection gun 1 and a second portion 10b of the subcutaneous injection interface assembly 10, the first portion of the subcutaneous injection interface assembly being configured to be removed from the piercing orientation within the flesh of an animal S.

[0150] 38A , the third inner surface portion 42 c of the inner surface 42 of the generally tubular body 34 of the needle hub 14 may define a curved or frustoconical surface extending into the first channel portion 44 a of the channel 44 of the needle hub 14. As shown in FIG38B , the peak of the curved or frustoconical surface defined by the third inner surface portion 42 c of the inner surface 42 of the generally tubular body 34 is generally aligned with the central axis A of the subcutaneous injection interface assembly 10. 10 -A 10 In addition, as shown in FIG38B , the central axis A of the subcutaneous injection interface assembly 10 is defined by the dotted line P1. 10 -A10 Another orthogonal imaginary line S1 extends through the proximal barb portion 130 of each leg 104a, 104b, 104c, 104d to mechanically couple the cannula carrier 100 to the area of ​​the circumferential notch or groove 65 formed by a portion of the outer body surface portion 62 of the outer surface 40 of the generally tubular body 34 of the needle hub 14. In addition, the central axis A of the subcutaneous injection interface assembly 10 is substantially the same as that of the cannula carrier 100. 10 -A 10 Another perpendicular imaginary line B1 extends through the distal end surface 38 of the needle hub 14. In addition, the central axis A of the subcutaneous injection interface assembly 10 is 10 -A 10 Yet another orthogonal imaginary line A1 extends through a region of the head 102 of the ferrule carrier 100 proximate the proximal end surface 108 of the body 106 of the head 102 of the ferrule carrier 100 .

[0151] Dashed line S1 generally delineates an area of ​​the subcutaneous injection interface assembly 10 in which the proximal barb portion 130 of each leg 104a, 104b, 104c, 104d of the cannula carrier 100 is configured to predictably mechanically separate from the surface portions 65a, 65b, 65c, 65d defining the circumferential notch or groove 65, thereby permitting the cannula carrier 100 to be mechanically separated from the needle hub 14. Furthermore, dashed line B1 generally delineates an area of ​​the subcutaneous injection interface assembly 10 in which the cannula 12 may (but is not intended to) structurally fail and break into its first and second parts. Thus, the cannula 12 and the portion of the needle hub 14 defining the first portion 10a of the subcutaneous injection interface assembly 10 are configured to remain attached to the injection gun 1. Similarly, another portion of the cannula 12 that is non-removably attached to the cannula carrier 100 by adhesive 200 defines a second portion 10b of the subcutaneous injection interface assembly 10 that is configured to be removed from the piercing orientation within the flesh of the animal S. Additionally, dashed line A1 generally delineates a "fill line," at which the amount of adhesive 200 should not further fill the first channel portion 116a or surround the cannula 12 in an area beyond the "fill line" A1. Furthermore, the distance extending between the "fill line" A1 and dashed line B1 can be configured to allow the cannula 12 to be positioned in the area between dashed lines A1 and B1 while not allowing any surface portion of the needle carrier 100 to engage or contact the distal end surface 38 of the needle hub 14.

[0152] Although the structural integrity of the cannula 12 is shown to potentially (but not intentionally) fail in association with the exemplary implementation of the subcutaneous injection interface assembly 10 shown in Figures 37A-37B and 38A-38B, resulting in the cannula 12 breaking into the first and second portions shown in Figures 37A and 37B, with reference to Figures 38C and 39A-39C, the proximal end 16 of the tubular body 16 of the cannula 12 PIt can be arranged in the needle hub 14 closer to the distal surface 38 of the needle hub 14. In addition, as shown in FIG38C, the proximal end 16 of the tubular body 16 of the cannula 12 P The proximal end of the cannula 12 may be disposed proximal to the dashed line P2 extending through the proximal end of the crimping pocket 68' defined by the outer head surface portion 68 of the outer surface 40 of the generally tubular body 34 of the needle hub 14. P is shown disposed proximal to the dashed line P2, but the proximal end 16 of the tubular body 16 of the cannula 12 P It may be arranged anywhere between, for example, the dotted line B1 and the dotted line P2.

[0153] 38D , another exemplary configuration of a subcutaneous injection interface assembly 10 is shown that is substantially similar to that of FIG 38C , except that the body 106 of the head 102 of the cannula carrier 100 includes an adhesive barrier wall 132 that includes a cannula passage 134. The adhesive barrier wall 132 confines the adhesive 200 within at least a portion of the first passage portion 116 a and prevents the adhesive 200 from axially migrating further toward the dashed line B1 such that the adhesive 200 does not surround a portion of the cannula that extends beyond the dashed line A1.

[0154] 38E, another exemplary configuration of the subcutaneous injection interface assembly 10 is shown, which is substantially similar to FIG. 38C, except that the second channel portion 116b is at an angle θ 116b Arrangement, the angle is not with the central axis A 10 -A 10 Orthogonal. In one example, the angle θ 116b The angle may be approximately equal to about 45° to facilitate controlled deposition of adhesive 200 into first channel portion 116a such that adhesive 200 substantially surrounds sleeve 12 up to fill line A1 , but not beyond fill line A1 .

[0155] 38F , another exemplary configuration of the subcutaneous injection interface assembly 10 is shown that is substantially similar to FIG. 38E , except that the body 106 of the head 102 of the cannula carrier 100 includes an adhesive barrier 132 that includes a cannula passage 134. The adhesive barrier 132 confines the adhesive 200 within at least a portion of the first passage portion 116 a and prevents the adhesive 200 from migrating axially further toward the dashed line B1 such that the adhesive 200 does not surround a portion of the cannula that extends beyond the dashed line A1. This arrangement, as seen in FIG. 38C and FIG. 39A , results in the proximal end 16 of the tubular body 16 of the cannula 12 being substantially confined to the cannula. P39B and 39C ), while the entire tubular body 16 of the cannula 12 remains connected to the second portion 10b of the subcutaneous injection interface assembly 10. Thus, as shown in FIG39C , the cannula 12 as a whole remains structurally intact and does not break into the first and second portions as shown in FIG37A and 37B (thus, no "break line" is defined).

[0156] Referring now to Figures 40 and 41A-41G , a method is shown for using any configuration of the exemplary subcutaneous injection interface assembly 10. Although Figures 40 and 41A-41G illustrate a method of using the subcutaneous injection interface assembly 10 described in Figures 33-35B , any of the other subcutaneous injection interface assemblies described herein may also be used in a substantially similar manner to that illustrated in Figures 40 and 41A-41G .

[0157] As described above, the design of the subcutaneous injection interface assembly 10 facilitates controlled separation of the cannula 12, cannula carrier 100, and adhesive 200 (which together define the second portion 10B of the subcutaneous injection interface assembly 10) relative to the needle hub 14 (which defines the first portion 10A of the subcutaneous injection interface assembly 10) (see, for example, Figures 37A-37B, Figures 39A-39C, and Figure 41E).

[0158] In some cases, the predictable and controlled separation of the second portion 10b of the subcutaneous injection interface assembly 10 from the first portion 10a of the subcutaneous injection interface assembly 10 can occur after the cannula 12 pierces the treatment subject S (see, for example, Figures 41A-41B). The treatment subject S can be, for example, an animal, such as a human or a non-human (i.e., an animal such as a pig). In other examples, the treatment subject S can be an inanimate object. The predictable and controlled separation of the second portion 10b of the subcutaneous injection interface assembly 10 from the first portion 10a of the subcutaneous injection interface assembly 10 alleviates the problem of separation of the cannula 12 from the entire needle hub 14, which could otherwise undesirably cause the cannula 12 to break and subsequently be lost (or make it difficult to easily locate the broken cannula) in the animal's flesh.

[0159] 40, the subcutaneous injection interface assembly 10 is shown connected to an injection device 1, such as an injection gun. The subcutaneous injection interface assembly 10 can be connected to the barrel portion 1 of the injection gun 1. B By arranging, for example, a first radially outward projection or ear 56 and a second radially outward projection or ear 58 extending from the barrel engaging portion 50, which extends from the outer surface 40 of the generally tubular body 34 of the needle hub 14 to the barrel portion 1 of the injection gun 1 BThe subcutaneous injection interface assembly 10 is then locked, for example, by a quarter turn to removably secure the barrel portion 1 extending from the barrel engaging portion 50 to the injection gun 1. B The first radially outward protrusion or ear 56 and the second radially outward protrusion or ear 58 are shown.

[0160] The injection gun I may include a fluid container C containing a fluid F (see also, e.g., FIG. 41C ). The fluid F may be metered from: (1) the container C; (2) through the injection gun I; (3) into the subcutaneous injection interface assembly 10; and (4) out of the subcutaneous injection interface assembly 10 and into the flesh of the subject S. When the user U depresses, for example, the actuator I A (e.g., a trigger), the injection gun 1 can be actuated to cause movement of the fluid F as described above. The injection gun 1 can be driven in any desired manner, such as: battery powered; pneumatic; manual; or a combination thereof.

[0161] 41A, the user can grasp the injection gun I and the distal end surface 20 of the tubular body 16 of the cannula 12 formed by the sharp piercing tip 32 is positioned on the outer surface S of the treatment object S. S Nearby, the outer surface may define the skin or hide of the treatment subject S. Referring to Figures 41A-41B, the user U may follow the arrow X A The direction is along the central axis A extending through the subcutaneous injection interface assembly 10 10 -A 10 An axial force is applied to the injection gun 1 so that the sharp piercing tip 32 formed by the distal end surface 20 of the tubular body 16 of the cannula 12 axially pierces the outer surface S of the treatment object S. S .

[0162] 38A and 41C, the outer surface S of the treatment object S S After having been axially penetrated by the cannula 12, the user U may optionally actuate the actuator 1 A, so as to cause fluid F to flow from: (1) container C; (2) through injection gun I; (3) into subcutaneous injection port assembly 10; and (4) out of subcutaneous injection port assembly 10 and into the flesh of subject S. In one example, first, fluid F may enter subcutaneous injection port assembly 10 from injection gun I at passage 44 formed by generally tubular body 34 of needle hub 14 via proximal opening 46 formed by proximal end surface 36 of generally tubular body 34 of needle hub 14. Then, second, fluid F may enter passage 26 extending through tubular body 16 of cannula 12 through proximal opening 28 formed by proximal end surface 18 of body 16 of cannula 12. Then, third, fluid F may exit passage 44 formed by generally tubular body 34 of needle hub 14 via distal opening 48 formed by distal end surface 38 of generally tubular body 34 of needle hub 14. Thereafter, fourthly, the fluid F may exit the passageway 26 extending through the tubular body 16 of the cannula 12 via the distal opening 30 formed by the distal end surface 20 of the body 16 of the cannula 12 .

[0163] Fluid F can be any desired composition intended for delivery to animal S. In some cases, fluid F can be a medicament, a drug, a vaccine, an anesthetic, or the like. Thus, fluid F may not include any type of fluid that is not intended to be injected into animal S. Although subcutaneous injection interface assembly 10 can also be used to inject fluid F into animal S, subcutaneous injection interface assembly 10 can be used to extract fluid F (e.g., blood) from animal S. Therefore, it should be understood that subcutaneous injection interface assembly 10 can deliver or receive fluid F.

[0164] 36A-36B, FIG. 39B and FIG. 41D, on the outer surface S of the treatment object S S After having been axially pierced by the cannula 12, the subject S may be pierced through the outer surface S by the sharp piercing tip 32 formed by the distal end surface 20 of the tubular body 16 of the cannula 12. S Therefore, if the user U has a firm grip on the injection gun 1, any movement of the subject S may cause the cannula 12 to be subjected to an indirect force relative to the central axis A extending through the subcutaneous injection interface assembly 10. 10 -A 10 One or more radial forces X R , the radial force X R The cannula 12 may be caused to bend or warp such that the central axis A extending through the axial center of the tubular body 16 of the cannula 12 12 -A 12 and extending through the central axis A of the subcutaneous injection interface assembly 10. 10 -A 10Without being aligned, the subcutaneous injection site assembly can be coaxially aligned with other components of the subcutaneous injection site assembly 10 , such as the needle hub 14 and the cannula carrier 100 .

[0165] Because the cannula carrier 100 can be formed of a flexible or substantially non-rigid material (eg, plastic), the cannula carrier 100 is subjected to one or more radial forces X. R Any stress generated and applied to the cannula 12 can be transferred from the cannula 12 to the cannula carrier 100; and any such stress transferred from the cannula 12 to the cannula carrier 100 can be directed and concentrated at a predetermined portion or area of ​​the subcutaneous injection interface assembly 10. The predetermined portion or area of ​​the subcutaneous injection interface assembly 10 that receives the concentrated stress is generally defined by the separation line of the subcutaneous injection interface assembly 10 (see, for example, the dotted line S1 in Figures 38B and 38C, which may be referred to as the separation line) passing through the portion or area of ​​the cannula carrier 100 and the needle hub 14 of the subcutaneous injection interface assembly 10. As described above, the separation line S1 generally demarcates the area with the cannula carrier 100 that can be mechanically separated from the needle hub 14. Also, depending on the insertion orientation of the cannula 12 relative to the needle hub 14, the cannula 12 may remain intact and unbroken (as shown in Figure 39C), or in some configurations, the cannula 12 may (but is not intended to) be broken due to one or more radial forces X. R The cannula 12 may structurally fail and fracture due to stress concentration caused by the cannula 12 (as shown in FIG. 37A and according to the fracture line B1 in FIG. 38B ). This stress concentration may also be transmitted to the cannula 12 and concentrated at, substantially at, around, along, or on the area of ​​the subcutaneous injection interface assembly 10 defined by the fracture line B1. In either implementation, the distal portion of the cannula 12 remains non-removably connected to the cannula carrier 100 by, for example, an adhesive 200.

[0166] As shown in FIG. 38A , the casing carrier 100 may be formed by a length L 100 This length is further defined by the sub-length L 100a and L 100b Limit. Sub-length L 100b It can also be represented by the sub-length part L 100b1 and L 100b2 limited.

[0167] Sub-length L 100a The sub-length L may be defined by the length of the head 102 of the cannula carrier 100. 100b The sub-length portion L may be defined by the length of each leg 104a, 104b, 104c, 104d of the ferrule carrier 100. 100b1 The sub-length portion L may be defined by the length of each leg 104a, 104b, 104c, 104d excluding the proximal barb portion 130 of each leg 104a, 104b, 104c, 104d.100b2 The length of each proximal barb 130 of each leg 104a, 104b, 104c, 104d may be defined.

[0168] Each length L 100a and L 100b And each sub-length part L 100b1 and L 100b2 The spacing or configuration may be selectively selected to optimize mechanical separation of the cannula carrier 100 from the needle hub 14 at the separation line S1. For example, when one or more radial forces X R When applied to the sleeve 12, sufficient leg length (eg, by the sub-length portion L 100b2 The length portion L may help allow each leg portion 104a, 104b, 104c, 104d of the cannula carrier 100 to be separated from the needle hub 14 at the separation line S1 without the body 106 of the cannula carrier 100 interfering with the distal end surface 38 of the needle hub 14. 100a and L 100b And each sub-length part L 100b1 and L 100b2 The combination of selective spacing or configurations combined with providing a UV adhesive for the adhesive portion 200 can strengthen the entire subcutaneous injection port assembly 10 .

[0169] As shown in FIG41D, the cannula carrier 100 can also allow the cannula 12 to be moved away from the central axis A extending through the subcutaneous injection interface assembly 10 because the stress transmitted from the cannula 12 to the needle hub 14 is directed and concentrated on a predetermined portion or area of ​​the cannula carrier 100 and the needle hub 14. 10 -A 10 (See, for example, the axis A of the cannula 12 and cannula carrier 100. 12 -A 12 、A 100 -A 100 ) bend or deviate. Therefore, the axis A of the sleeve 12 and the sleeve carrier 100 12 -A 12 、A 100 -A 100 Typically offset from the axis A of the needle hub 14 14 -A 14 , which can be maintained with the central axis A extending through the subcutaneous injection interface assembly 10 10 -A 10 coincide.

[0170] 37A-37B and 41E , the stress transmitted from the cannula 12 to the interface assembly (10) is directed and concentrated at a predetermined portion or area (e.g., at separation line S1), which can continue to bend the cannula carrier 100 relative to the needle hub 14 until the cannula carrier 100 is controllably mechanically separated from the needle hub 14 by flexibly disconnecting the proximal barb portion 130 of each leg 104a, 104b, 104c, 104d of the cannula carrier 100 from the surface portion 65a, 65b, 65c, 65d defining the circumferential notch or groove 65 to allow the cannula carrier 100 to be mechanically separated from the needle hub 14. As a result, the second portion 10b of the subcutaneous injection interface assembly 10, including the cannula carrier 100, the cannula 12, and the adhesive 200, can be predictably and controllably separated (at or substantially at, around, along, or at the break line B1) from the first portion 10a of the subcutaneous injection interface assembly 10, defined by the needle hub 14. After separation, each leg 104a, 104b, 104c, 104d of the cannula carrier 100 can deform, expand, or flare outward, which can increase visibility for the user to help locate the location for penetrating the cannula 12 into the flesh of the animal S.

[0171] As shown in FIG41E , because the cannula holder 100 is inseparably coupled to the cannula 12 by the adhesive 200, the user U can easily identify the position of the animal S where the cannula 12 is pierced into the skin of the animal S. The position of the animal S where the cannula 12 is pierced into the skin of the animal S is easily identifiable, for example, the cannula holder 100 of the second portion 10 b of the subcutaneous injection interface assembly 10 rests on the skin S of the animal S. S or on animal hide (while the sleeve 12 is not visible to the user U because the sleeve 12 is contained within and covered by the hide of the animal S).

[0172] Thereafter, as shown in FIG41F , user U may pinch or grasp second portion 10 b of subcutaneous injection interface assembly 10 and apply a pulling force to second portion 10 b of subcutaneous injection interface assembly 10 (which also includes pierced cannula 12). As shown in FIG41G , due to the pulling force applied by user U to second portion 10 b of subcutaneous injection interface assembly 10, cannula 12 is removed from the flesh of animal S, so that cannula 12 is not lost or thereby undesirably retained in the flesh of animal S.

[0173] Many implementations have been described. However, it should be understood that various modifications may be made without departing from the spirit and scope of this disclosure. Therefore, other implementations are within the scope of the following claims. For example, the actions recited in the claims may be performed in a different order and still achieve the desired results.

[0174] The terms used herein are only used to describe the purpose of specific exemplary configurations and are not intended to be limiting. As used herein, the singular articles "a", "an" and "the" may also be intended to include plural forms, unless the context clearly indicates otherwise. The terms "comprise", "include" and "have" are inclusive and therefore specify the presence of features, steps, operations, elements and / or parts, but do not exclude the presence or addition of one or more other features, steps, operations, elements, parts and / or groups thereof. The methods, steps, processes and operations described herein should not be interpreted as having to be performed in the specific order discussed or described, unless specifically indicated as the order of execution. Additional or alternative steps may be adopted.

[0175] When an element or layer is referred to as being "on," "engaged to," "connected to," "attached to," or "coupled to" another element or layer, it may be directly on, engaged, connected, attached, or coupled to the other element or layer, or there may be intervening elements or layers. Conversely, when an element is referred to as being "directly on," "directly engaged to," "directly attached to," "directly attached to," or "directly coupled to" another element or layer, there may be no intervening elements or layers. Other words used to describe the relationship between these elements should be interpreted in a similar manner (e.g., "between" versus "directly between," "adjacent" versus "directly adjacent," etc.). As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.

[0176] The terms first, second, third, etc. may be used herein to describe various elements, components, regions, layers, and / or sections. These elements, components, regions, layers, and / or sections should not be limited by these terms. These terms may only be used to distinguish one element, component, region, layer, or section from another region, layer, or section. Terms such as "first," "second," and other numerical terms do not imply a sequence or order unless there is a clear indication in the context. Therefore, without departing from the teachings of the example configurations, the first element, component, region, layer, or section discussed below may be referred to as a second element, component, region, layer, or section.

Claims

1. A subcutaneous injection port assembly (10) for injecting or withdrawing a fluid (F) from an animal (S), comprising: Needle holder (14); The sleeve (12) has a central axis (A) extending therethrough. 12 –A 12 );as well as A ferrule carrier (100) having a head (102) and a plurality of legs (104), wherein a plurality of legs (104) of the cannula carrier (100) extend from the head (102) of the cannula carrier (100) toward the needle seat (14), wherein the casing carrier (100) is irremovably connected to the casing (12), and wherein when the animal (S) moves during the injection or withdrawal of the fluid (F) and the cannula (12) is subjected to a rotation relative to the central axis (A) of the cannula (12) 12 –A 12 ) radial force (X R ), the plurality of legs (104) of the cannula carrier (100) are removably connected to the needle hub (14).

2. The subcutaneous injection site assembly (10) of claim 1, further comprising an adhesive (200) connecting the cannula (12) to the cannula carrier (100).

3. The subcutaneous injection interface assembly (10) according to claim 2, wherein: The ferrule carrier (100) includes an adhesive deposition channel (122), and wherein the adhesive (200) is deposited into the adhesive deposition channel (122) of the ferrule carrier (100).

4. The subcutaneous injection interface assembly (10) according to claim 1, wherein: Each of the plurality of legs (104) of the cannula carrier (100) includes a barb (130), and wherein the needle hub (14) includes a recess (65) sized to receive the barb (130) of the plurality of legs (104).

5. The subcutaneous injection interface assembly (10) according to claim 1, wherein: The sleeve (12) is arranged on: extending through a needle hub passage (44) of the needle hub (14); and Extending through the ferrule carrier channel (116) of the ferrule carrier (100).

6. The subcutaneous injection interface assembly (10) according to claim 5, wherein: The outer surface (22) of the cannula (12) is secured to an inner surface (42b) defining the needle hub passage (44).

7. The subcutaneous injection interface assembly (10) according to claim 5, wherein: A first portion of the outer surface (22) of the sleeve (12) is disposed in a spaced relationship relative to a first inner surface portion (112a), the first inner surface portion defining a first sleeve carrier channel portion (116a) of the sleeve carrier channel (116) of the sleeve carrier (100), wherein a second portion of the outer surface (22) of the sleeve (12) is disposed adjacent a second inner surface portion (112b), the second inner surface portion defining a second sleeve carrier channel portion (116b) of the sleeve carrier channel (116) of the sleeve carrier (100) to fluidically seal the second sleeve carrier channel portion (116b) of the sleeve carrier channel (116) of the sleeve carrier (100).

8. The subcutaneous injection interface assembly (10) according to claim 1, wherein: The plurality of legs (104) includes at least two legs (104).

9. The subcutaneous injection port assembly according to claim 1, wherein the needle hub (14) has a central axis (A) extending therethrough 14 -A 14 ), the central axis (A 14 -A 14 ) and the central axis (A) of the sleeve (12) 12 -A 12 ) overlap, and in, At least one leg (104) of the plurality of legs (104) is configured to be responsive to the radial force (X R ) and away from the central axis (A) of the needle seat (14) 14 -A 14 )move.

10. The subcutaneous injection site assembly of claim 1, wherein the legs are formed of a flexible or non-rigid material to allow the cannula carrier to separate from the needle hub when a radial force is applied to the cannula.

11. A subcutaneous injection port assembly (10) for injecting or withdrawing fluid (F) from an animal (S), comprising: A first subcutaneous injection interface assembly portion (10a) defined by: Needle holder (14); as well as A second subcutaneous injection interface assembly portion (10b) detachably connected to the first subcutaneous injection interface assembly portion (10a), wherein the second subcutaneous injection interface assembly portion (10b) is defined by: The sleeve (12) has a central axis (A) extending therethrough. 12 –A 12 );as well as A ferrule carrier (100) having a head (102) and a plurality of legs (104), wherein the plurality of legs (104) extend from the head (102) of the cannula carrier (100) toward the needle hub (14), wherein the cannula carrier (100) is non-removably connected to the cannula (12), and wherein when the animal (S) moves during injection or withdrawal of the fluid (F) and the cannula (12) is subjected to a rotation relative to the central axis (A) of the cannula (12), 12 –A 12 ) radial force (X R ), the plurality of legs (104) of the cannula carrier (100) are removably connected to the needle hub (14).

12. The subcutaneous injection site assembly (10) of claim 11, further comprising an adhesive (200) connecting the cannula (12) to the cannula carrier (100).

13. The subcutaneous injection interface assembly (10) of claim 12, wherein: The ferrule carrier (100) includes an adhesive deposition channel (122), and wherein the adhesive (200) is deposited into the adhesive deposition channel (122) of the ferrule carrier (100).

14. The subcutaneous injection port assembly (10) of claim 11, wherein: Each of the plurality of legs (104) of the cannula carrier (100) includes a barb (130), and wherein the needle hub (14) includes a recess (65) sized to receive the barb (130) of the at least one leg (104).

15. The subcutaneous injection port assembly (10) of claim 11, wherein: The sleeve (12) is arranged on: extending through a needle hub passage (44) of the needle hub (14); and Extending through the ferrule carrier channel (116) of the ferrule carrier (100).

16. The subcutaneous injection port assembly (10) of claim 15, wherein: The outer surface (22) of the cannula (12) is secured to an inner surface (42b) defining the needle hub passage (44).

17. The subcutaneous injection port assembly (10) of claim 15, wherein: A first portion of the outer surface (22) of the sleeve (12) is disposed in a spaced relationship relative to a first inner surface portion (112a), the first inner surface portion defining a first sleeve carrier channel portion (116a) of the sleeve carrier channel (116) of the sleeve carrier (100), wherein a second portion of the outer surface (22) of the sleeve (12) is disposed adjacent a second inner surface portion (112b), the second inner surface portion defining a second sleeve carrier channel portion (116b) of the sleeve carrier channel (116) of the sleeve carrier (100) to fluidically seal the second sleeve carrier channel portion (116b) of the sleeve carrier channel (116) of the sleeve carrier (100).

18. The subcutaneous injection port assembly (10) of claim 11, wherein: The plurality of legs (104) includes at least two legs (104).

19. The subcutaneous injection port assembly according to claim 11, wherein the needle hub (14) has a central axis (A) extending therethrough 14 -A 14 ), the central axis (A 14 -A 14 ) and the central axis (A) of the sleeve (12) 12 -A 12 ) overlap, and in, At least one leg (104) of the plurality of legs (104) is configured to be responsive to the radial force (X R ) and away from the central axis (A) of the needle seat (14) 14 -A 14 )move.

20. The subcutaneous injection site assembly of claim 11, wherein the legs are formed of a flexible or non-rigid material to allow the cannula carrier to separate from the needle hub when a radial force is applied to the cannula.

Images