Absorbable occlusion system

Abstract

The present application relates to a kind of absorbable occlusion system, including absorbable occlusion device and pusher, and the absorbable occlusion system includes occlusion frame and the proximal end head and the distal end head respectively arranged in the two ends of occlusion frame, the through hole is opened in the proximal end head, first connecting part is provided on the distal end head, pusher is detachably connected with the proximal end head, pusher includes pusher and adjusting piece, pusher, through hole and occlusion frame are communicated, adjusting piece is movably arranged in pusher, and second connecting part is arranged on adjusting piece, adjusting piece is movably arranged in through hole and extends into occlusion frame, and first connecting part and second connecting part cooperate, so that the distal end head and adjusting piece are detachably connected.The absorbable occlusion system can omit locking piece.

Description

Technical Field

[0001] This invention relates to the field of medical devices, and in particular to an absorbable occlusion system. Background Technology

[0002] This section provides only background information relevant to this disclosure and is not necessarily prior art.

[0003] Transcatheter interventional therapy is a rapidly developing treatment method in recent years, and its application areas are becoming increasingly wide. This method involves placing devices and / or drugs into the heart, arteries, veins, and other parts of the body. The devices used can include cardiac occluders, vascular plugs, and vascular filters.

[0004] Traditional cardiac occluders and vascular plugs are generally made of shape memory alloys. Shape memory alloys are highly elastic and can readily return to their original shape after release, conforming well to the tissue at the defect site. However, current shape memory alloys are generally non-corrosive or non-degradable in the body. Once endothelialization is achieved and complete occlusion is realized, these devices, such as vascular plugs made of shape memory alloys, will remain permanently in the body, potentially posing long-term clinical risks.

[0005] Cardiac occluders, vascular plugs, or other implantable devices made of absorbable polymer materials, while degradable within the body, allowing for gradual degradation and absorption of degradation products without residue, are still relatively soft and difficult to mold. After delivery, these polymer-based devices cannot automatically return to their final or expanded state, requiring assisted molding. To address this, existing occluders incorporate an axially extending locking element within the occlusion frame. One end of the locking element is fixedly connected to the distal end cap, while the other end is detachably connected to the proximal end cap. During implantation, the other end of the locking element is disconnected from the proximal end cap. By pulling the locking element to restore the device to its final or expanded state, the other end of the locking element is then reconnected to the proximal end cap to lock the device in place.

[0006] However, locking components are generally small in size and require a structure that can be detachably connected to the conveying device, which places high demands on the manufacturing process. Summary of the Invention

[0007] Therefore, it is necessary to provide an absorbable sealing system that can eliminate the need for locking components.

[0008] An absorbable occlusion system includes an absorbable occluder and a pusher. The absorbable occlusion system includes an occlusion frame and a proximal end cap and a distal end cap respectively disposed at both ends of the occlusion frame. The proximal end cap has a through hole, and the distal end cap has a first connecting portion. The pusher is detachably connected to the proximal end cap. The pusher includes a pusher and an adjusting member. The pusher and the through hole communicate with the occlusion frame. The adjusting member movably passes through the pusher and has a second connecting portion. The adjusting member movably passes through the through hole and extends into the occlusion frame. The first connecting portion cooperates with the second connecting portion to detachably connect the distal end cap and the adjusting member.

[0009] In one embodiment, the first connecting portion is a threaded hole extending axially from one end of the distal end cap to the other end, and the second connecting portion is an external thread disposed at the distal end of the adjusting member.

[0010] In one embodiment, the sealing frame includes a plurality of sealing discs arranged at axial intervals, with adjacent sealing discs connected by a waist section.

[0011] In one embodiment, a fastener is fitted onto the waist.

[0012] In one embodiment, the fixing element is a flexible sleeve or a ring coil.

[0013] In one embodiment, the occlusion disc is formed by braiding filaments, and the occlusion disc includes a proximal disc surface, a distal disc surface, and ridges connecting the proximal disc surface and the distal disc surface. The braiding density of the ridges is greater than the braiding density of the proximal disc surface and the braiding density of the distal disc surface.

[0014] In one embodiment, on the opposite surfaces of any two adjacent sealing discs, one disc is provided with a first adhesive part and the other disc is provided with a second adhesive part. The first adhesive part and the second adhesive part cooperate with each other to lock the axial distance between any two adjacent sealing discs.

[0015] In one embodiment, the first adhesive portion and the second adhesive portion form an adhesive tape fastener; or, the first adhesive portion and the second adhesive portion form a snap fastener.

[0016] In one embodiment, the sealing frame includes multiple braided filaments and multiple fiber strands, both made of absorbable material, and the multiple braided filaments and multiple fiber strands are woven together in an intersecting manner to form a mesh structure.

[0017] In one embodiment, the material of the occlusion frame is selected from at least one of polylactic acid, polyglycolic acid, polylactic-co-hydroxyacetic acid copolymer, polyhydroxy fatty acid ester, polydioxanone, polycaprolactone, polygluconic acid, polyhydroxybutyric acid, polyanhydride, polyphosphate, polydioxanone, and polycarbonate.

[0018] The aforementioned absorbable occluder system features a detachable connection between the adjusting element and the distal end cap, and a detachable connection between the pushing element and the proximal end cap. During implantation, the pushing element is fixed, and the adjusting element is pulled proximally to move the distal end cap of the absorbable occluder closer to the proximal end cap, thereby restoring the absorbable occluder to its expanded state. Then, the connections between the adjusting element and the distal end cap, and between the pushing element and the proximal end cap, are released. This method eliminates the need for a locking element, thus eliminating the steps of preparing the locking element and connecting it to the distal end cap, reducing processing requirements. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of an absorbable plugging system according to one embodiment;

[0020] Figure 2 This is a schematic diagram of the structure of an absorbable plugging device according to one embodiment;

[0021] Figure 3 This is a schematic diagram of the structure of a pusher according to one embodiment;

[0022] Figure 4 This is a schematic diagram of the loading status of the absorbable plugging system;

[0023] Figures 5-7 This is a schematic diagram of the release process;

[0024] Figure 8 This is a schematic diagram of the structure of an absorbable plug according to another embodiment;

[0025] Figure 9 This is a schematic diagram of the structure of an absorbable plugging device according to another embodiment. Detailed Implementation

[0026] To make the above-mentioned objects, features, and advantages of the present invention more apparent and understandable, specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of the present invention. However, the present invention can be practiced in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0027] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.

[0028] In the field of interventional medical devices, "distal" is defined as the end furthest from the operator during surgery, and "proximal" is defined as the end closest to the operator during surgery. "Axial" refers to the direction parallel to the line connecting the center of the distal and proximal ends of the medical device, and "radial" refers to the direction perpendicular to the aforementioned axial direction. "Circumferential" refers to the circumferential direction, that is, the direction surrounding the axis of the tubular instrument.

[0029] Please see Figure 1 An absorbable occlusion system 1 according to one embodiment includes an absorbable occluder 10 and a pusher 20. The absorbable occluder 10 and the pusher 20 are detachably connected. The pusher 20 is used to push the absorbable occluder 10 to the lesion site and change the absorbable occluder 10 to an expanded state.

[0030] Please see Figure 2 The absorbable occluder 10 includes an occlusion frame 110, a proximal end cap 120, and a distal end cap 130. The occlusion frame 110 has a central axis II-II extending axially. The proximal end cap 120 and the distal end cap 130 are respectively disposed at the proximal end and the distal end of the occlusion frame 110, and are respectively fixedly connected to the occlusion frame 110.

[0031] The occlusion frame 110, proximal end cap 120, and distal end cap 130 are all made of absorbable material. In one embodiment, the absorbable material is selected from at least one of polylactic acid, polyglycolic acid, polylactic-co-hydroxyacetic acid copolymer, polyhydroxyalkanoates, polydioxanone, polycaprolactone, polygluconic acid, polyhydroxybutyric acid, polyanhydride, polyphosphate, polydioxanone, and polycarbonate. The materials of the occlusion frame 110, proximal end cap 120, and distal end cap 130 may be the same or different.

[0032] It is understood that the materials used for the occlusion frame 110, proximal end cap 120, and distal end cap 130 are not limited to those listed above. Any absorbable material that meets biocompatibility requirements and can be used to prepare the occlusion frame 110, proximal end cap 120, and distal end cap 130 is applicable.

[0033] A through hole 122 is provided on the proximal end cap 120, and a first connecting portion 132 is provided on the distal end cap 130. The central axis II-II passes through the through hole 122 and the first connecting portion 132 in sequence. In one embodiment, the first connecting portion 132 is a threaded hole provided on the distal end cap 130. The threaded hole extends axially from the proximal end to the distal end of the distal end cap 130.

[0034] Please see Figure 3 The pusher 20 includes a pusher 210 and an adjuster 220.

[0035] The pusher 210 includes a tube 212 and a connector 214 connected to the distal end of the tube 212. The tube 212 has an axially extending inner cavity. The connector 214 has an axially extending through hole. The through hole of the connector 214 communicates with the inner cavity of the tube 212. The pusher 210 is detachably connected to the proximal end cap 120. In one embodiment, the connector 214 and the proximal end cap 120 are threadedly connected, such that the pusher 210 is detachably connected to the absorbable plug 10. In one embodiment, the through hole of the connector 214 is a threaded hole, and the proximal end cap 120 is provided with external threads. In another embodiment, the through hole 122 of the proximal end cap 120 is a threaded hole, and the outer wall of the connector 214 is provided with external threads.

[0036] The adjusting member 220 includes a rod 222 and a second connecting portion 224 connected to the distal end of the rod 222. In one embodiment, the rod 222 and the second connecting portion 224 are an integral structure. In another embodiment, the rod 222 and the second connecting portion 224 are fixedly connected by means known to those skilled in the art, including but not limited to welding and bonding. In one embodiment, the second connecting portion 224 is an externally threaded structure provided at the distal end of the rod 222.

[0037] When the pusher 210 is connected to the absorbable plug 10, the pusher 210, the through hole 122, and the plugging frame 110 are connected. The adjusting member 220 is movably inserted through the pusher 210 and the through hole 122, and extends into the plugging frame 110. Furthermore, the second connecting portion 224 of the adjusting member 220 extends into the distal end cap 130, and the second connecting portion 224 cooperates with the first connecting portion 132 of the distal end cap 130, so that the distal end cap 130 and the adjusting member 220 are detachably connected.

[0038] Please see Figure 4 The pusher 20 also includes a sheath 230. During loading, after connecting the pusher 210 to the proximal end cap 120 and the adjusting member 220 to the distal end cap 130, keep the pusher 210 stationary and push the adjusting member 220 distally to stretch the absorbable occluder 10. Maintaining the relative position of the adjusting member 220 and the pusher 210, pull the pusher 210 proximally to draw the stretched absorbable occluder 10 into the sheath 230. Please refer to the following instructions for use. Figure 5 , Figure 6 and Figure 7Under the traction of the guidewire (not shown), the sheath 230 carrying the absorbable occluder 10 is delivered to the lesion site. The pusher 210 is then pushed distally to push the absorbable occluder 10 out of the sheath 230. Next, keeping the pusher 210 stationary, the adjuster 220 is pulled proximally to move the distal end cap 130 of the absorbable occluder 10 closer to the proximal end cap 120, causing the occlusion frame 110 to be compressed and change from a stretched state to an expanded state. When the radial dimension of the occlusion frame 110 gradually increases until the outer surface of the occlusion frame 110 abuts against the inner wall of the anatomical structure, the connection between the adjuster 220 and the distal end cap 130 is released (e.g., ...). Figure 6 (As shown), then disconnect the pusher 210 from the proximal end cap 120, and withdraw the pusher 210, adjustment member 220, and sheath 230 out of the body, leaving the absorbable occluder 10 inside the body (as shown). Figure 7 (As shown).

[0039] The aforementioned absorbable occlusion system 1 is detachably connected to the distal end cap 130 via an adjusting member 220, and detachably connected to the proximal end cap 120 via a pushing member 210. During implantation, the pushing member 210 is fixed, and the adjusting member 220 is pulled proximally to move the distal end cap 130 of the absorbable occluder 10 closer to the proximal end cap 120, thereby causing the absorbable occluder 10 to gradually change towards an expanded state. Then, the connection between the adjusting member 210 and the distal end cap 130, and the connection between the pushing member 220 and the proximal end cap 120, are respectively released. Through the cooperation of the adjusting member 210, the pushing member 220, and the distal end cap 130, the absorbable occluder 10 can be restored from a stretched state to an expanded state without the need for a locking member.

[0040] By cooperating with the absorbable plug 10 and the pusher 20, the absorbable plug 10 can be stretched, loaded, and formed without the need for additional locking components. Furthermore, the connection between the locking components and the plugging frame 110 is omitted, thus eliminating corresponding manufacturing steps and reducing processing requirements. After manufacturing, there is no need to test the connection strength between the locking components and the plugging frame 110. This improves production efficiency.

[0041] Furthermore, by omitting the locking element, it is beneficial to reduce the degradation products of the absorbable occluder 10, reduce the metabolic burden on the organism, reduce the occurrence of inflammation, and lower long-term clinical risks.

[0042] Please return Figure 2 In one embodiment, the sealing frame 110 includes a plurality of sealing discs 111 arranged axially at intervals, with adjacent sealing discs 111 connected by a waist portion 112. The radial length of the waist portion 112 is less than the radial length of the sealing discs 111. The radial lengths of the plurality of sealing discs 111 are equal, while their axial lengths may be equal or unequal.

[0043] In one embodiment, such as Figure 2 As shown, the occlusion frame 110 includes three occlusion discs 111. The radial lengths of the three occlusion discs 111 are equal, and the axial lengths of the two occlusion discs 111 located on both sides are equal and smaller than the axial length of the occlusion disc 111 located in the middle. The axial length of the occlusion disc 111 located in the middle is larger. When the absorbable occluder 10 is applied to occlude luminal anatomical structures, it helps to increase the contact area between the occlusion disc 111 and the inner wall of the luminal anatomical structure, improves the reliability of anchoring, and can adapt to individuals with longer lesion sites.

[0044] It is understood that in other embodiments, the number of sealing discs 111 is not limited to three. For example, in one embodiment, the number of sealing discs 111 is four, and the radial length and axial length of the four sealing discs 111 are equal. Alternatively, the radial lengths of the four sealing discs 111 are equal, but the axial lengths of the two middle sealing discs 111 are larger.

[0045] The sealing frame 110 is woven from absorbable braided yarn. See also... Figure 8 In one embodiment, the occlusion disc 111 includes a proximal disc surface 1111, a distal disc surface 1112, and a ridge 1113 connecting the proximal disc surface 1111 and the distal disc surface 1112. The braiding density of the ridge 1113 is greater than that of the proximal disc surface 1111 and the distal disc surface 1112. When the absorbable occluder 10 is implanted into a luminal anatomy, such as a blood vessel, the ridge 1113 abuts against the vessel wall. The higher braiding density of the ridge 1113 results in greater friction between the ridge 1113 and the vessel wall, thereby improving anchoring performance.

[0046] like Figure 8 As shown, the occlusion plate 111 in the middle has a larger axial length, the ridge 1113 has a larger axial length, and the ridge 1113 has a larger weaving density, which makes the contact area between the occlusion frame 10 and the blood vessel wall larger, and the friction greater, resulting in better anchoring performance.

[0047] Furthermore, by simply increasing the weaving density of the spine 1113 to improve the anchoring performance, the remaining parts of the occlusion frame 110 have a lower weaving density, resulting in a smaller amount of degradation products of the absorbable occluder 10, which helps reduce inflammation and lowers the risk of long-term clinical use.

[0048] In one embodiment, the sealing plug 110 includes multiple braided filaments and multiple fiber strands. Both the braided filaments and the fiber strands are absorbable materials, and the multiple braided filaments and multiple fiber strands are woven together in an intersecting manner to form a mesh structure. Each fiber strand is formed by the convergence of multiple fiber strands.

[0049] In one embodiment, the materials of the braided filaments and the fiber yarns are selected from at least one of polylactic acid (PLA), racemic PLA, polyglycolic acid, polylactic-co-hydroxyacetic acid copolymer, polyhydroxyalkanoates, polydioxanone, polycaprolactone, polygluconic acid, polyhydroxybutyric acid, polyanhydride, polyphosphate ester, polyglycolic acid, and polydioxanone. The materials of the braided filaments and the fiber yarns may be the same or different.

[0050] The absorbable occluder 10 is composed of multiple fiber strands, each of which is relatively loose in volume. This allows the multiple fiber strands to quickly attract blood cells, forming a thrombus on the surface of the fiber strands and gradually creating a denser structure. This enables rapid occlusion, resulting in good immediate occlusion performance. Therefore, the absorbable occluder 10 can omit the flow-blocking membrane.

[0051] In one embodiment, the specification range of each fiber in the multi-strand fiber yarn is 50D / 18F-600D / 144F.

[0052] In one embodiment, the specification range of each fiber in the multi-strand yarn is 50D / 72F to 600D / 72F. In another embodiment, the specification range of each fiber in the multi-strand yarn is 90D / 72F to 300D / 72F. The above specifications mean that, taking 50D / 72F as an example, each fiber contains 72 fibers, and the total mass of these 72 fibers is 50 Tennell (D). Other specifications have the same meaning and will not be elaborated further here.

[0053] In one embodiment, both the braided filaments and the fiber yarns are made of polylactic acid (PLA). The diameter of the braided filaments is 0.1–0.5 mm, and the fiber yarn specifications are 75D / 36F–400D / 144F. The ratio of the number of braided filaments to the number of fiber yarn strands is 1:3–7:1. This optimized configuration allows for staggered degradation of the fiber yarns and braided filaments, thus preventing the concentrated release of degradation products, avoiding tissue inflammation, and ensuring safe use.

[0054] Please continue reading. Figure 8 In one embodiment, the absorbable occluder 10 further includes a retainer 150, which is fitted onto the waist portion 112. The retainer 150 helps maintain the shape of the absorbable occluder 10 and prevents deformation due to impact from fluids (such as blood flow).

[0055] In one embodiment, the fastener 150 is a flexible sleeve made of a polymer material, with a channel formed in the middle of the flexible sleeve extending axially from the distal end to the proximal end. The flexible sleeve is fitted onto the waist portion 112, and the inner wall of the flexible sleeve is in contact with the outer peripheral surface of the waist portion 112.

[0056] In one embodiment, the fixation member 150 is a ring-shaped coil. The ring-shaped coil is formed of polymer thread. The polymer thread is a flexible thread such as polymer fiber thread or polymer medical suture. In one embodiment, the polymer thread is an absorbable polymer thread so that the entire absorbable occluder 10 can be absorbed by the body. Polymer threads such as polymer fiber thread or polymer medical suture are relatively soft, and the ring-shaped coil formed by the polymer thread wrapped around the outer periphery of the waist 112 is also relatively soft, so that the setting of the fixation member 150 does not significantly increase the overall rigidity of the absorbable occluder 10. Even if the number of fixation members 150 is greater than 2, the absorbable occluder 10 can still maintain sufficient flexibility. Furthermore, the method of forming the fixation member 150 on the waist 112 using polymer thread is relatively simple to prepare or process and easy to operate.

[0057] The polymer thread is wrapped around the waist 112 one or more times to form a fastener 150.

[0058] Please see Figure 9 In one embodiment, on the opposing surfaces of any two adjacent sealing discs 111, one is provided with a first adhesive portion 162 and the other with a second adhesive portion 164. The first adhesive portion 162 and the second adhesive portion 164 cooperate with each other to lock the axial distance between any two adjacent sealing discs 111. The adjacent sealing discs 111 are brought closer together by the adjusting member 220 so that the first adhesive portion 162 and the second adhesive portion 164 fit together to lock the axial distance between any two adjacent sealing discs 111.

[0059] When the first adhesive portion 162 and the second adhesive portion 164 approach each other, they adhere to each other, thereby adhering the two adjacent sealing discs 111 together and locking the overall axial length of the absorbable occluder 10. Furthermore, this locking method eliminates the need for rigid, axially extending locking elements, resulting in better flexibility of the absorbable occluder 10.

[0060] Furthermore, by setting the first adhesive part 162 and the second adhesive part 164, the overall length of the absorbable plug 10 can be adjusted. It is possible to stick only two plug discs 111 together or to stick all the plug discs 111 together as needed.

[0061] Furthermore, the two adjacent sealing discs 111 are bonded together, which helps to improve the radial support performance of the sealing frame 110, thereby improving the reliability of the anchoring.

[0062] The first adhesive part 162 and the second adhesive part 164 are flexible structures. In one embodiment, one of the first adhesive part 162 and the second adhesive part 164 is a hook structure and the other is a bristle structure. The first adhesive part 162 and the second adhesive part 164 form a Velcro or hook and loop fastener, thereby enabling two adjacent sealing discs 111 to be adhered together.

[0063] The first adhesive portion 162 extends on the surface of the sealing disc 111. The second adhesive portion 164 extends on the surface of the sealing disc 111. Compared with a rigid, axially extending locking member, the use of flexible first adhesive portion 162 and second adhesive portion 164 enables the absorbable occluder 10 to have better compliance.

[0064] In one embodiment, both the first adhesive portion 162 and the second adhesive portion 164 are annular, and the first adhesive portion 162 and the second adhesive portion 164 are arranged around the central axis of the sealing disc 111.

[0065] In one embodiment, the first adhesive portion 162 covers the entire surface of the sealing disc 111, and the opposite second adhesive portion 164 covers the opposite entire surface of the adjacent sealing disc 111 to increase the adhesive area, so that the two adjacent sealing discs 111 are reliably bonded together, thereby improving the radial support performance.

[0066] In one embodiment, the first adhesive portion 162 and the second adhesive portion 164 are non-annular structures, such as regular or irregular shapes like square, rectangle, or circle. Multiple first adhesive portions 162 or multiple second adhesive portions 164 can be provided on one surface of the sealing disc 111.

[0067] It is understood that, regardless of the shape of the first adhesive part 162 and the second adhesive part 164, the first adhesive part 162 and the second adhesive part 164 are arranged opposite each other on the opposite surfaces of any two adjacent sealing discs 111.

[0068] Both the first adhesive portion 162 and the second adhesive portion 164 are made of absorbable material, making the absorbable occluder 10 a completely absorbable device. For example, the first adhesive portion 162 is a hook structure made of absorbable material, and the second adhesive portion 140 is a filament structure made of absorbable material.

[0069] In one embodiment, the materials of the first adhesive portion 162 and the second adhesive portion 164 are selected from at least one of polylactic acid (PLA), polyglycolic acid (PGA), polylactic-co-glycolic acid copolymer (PLGA), polyhydroxyalkanoate (PHA), polydioxanone (PDO), polycaprolactone (PCL), polygluconic acid, polyhydroxybutyric acid, polyanhydride, polyphosphate (PPE), polydioxanone, and polycarbonate (PC). The materials of the first adhesive portion 162 and the second adhesive portion 164 may be the same or different.

[0070] In another embodiment, one of the first adhesive portion 162 and the second adhesive portion 164 is a male snap and the other is a female snap, forming a male-female snap, thereby enabling the adhesion of two adjacent sealing discs 111 together. The first adhesive portion 162 and the second adhesive portion 164 of this structure can also be made of an absorbable polymer material.

[0071] The aforementioned absorbable plugging system 1, through the cooperation of the adjusting member 210, the pushing member 220, and the distal end cap 130, enables the absorbable plug 10 to return from a stretched state to an expanded state without the need for a locking member. Furthermore, by combining the first adhesive part 162 and the second adhesive part 164, the axial distance of the absorbable plug 10 can be further adjusted to improve radial support performance and thus enhance anchoring performance.

[0072] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0073] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims.

Claims

1. An absorbable plugging system, characterized in that, The system includes an absorbable occluder and a pusher. The absorbable occluder system includes an occluder frame and a proximal end cap and a distal end cap respectively disposed at both ends of the occluder frame. The proximal end cap has a through hole, and the distal end cap has a first connecting part. The pusher includes a pusher and an adjusting part. The pusher is detachably connected to the proximal end cap. The pusher and the through hole are connected to the occluder frame. The adjusting part is movably inserted through the pusher and has a second connecting part. The adjusting part is movably inserted through the through hole and extends into the occluder frame. The first connecting part cooperates with the second connecting part to detachably connect the distal end cap and the adjusting part. The sealing frame includes multiple sealing discs arranged at intervals along the axial direction. On the opposite surfaces of any two adjacent sealing discs, one disc has a first adhesive part and the other disc has a second adhesive part. The first adhesive part and the second adhesive part cooperate with each other to lock the axial distance between any two adjacent sealing discs.

2. The absorbable plugging system according to claim 1, characterized in that, The first connecting part is a threaded hole extending axially from one end of the distal end cap to the other end, and the second connecting part is an external thread provided at the distal end of the adjusting member.

3. The absorbable plugging system according to claim 1, characterized in that, Two adjacent sealing discs are connected by a waist section.

4. The absorbable plugging system according to claim 3, characterized in that, A fastener is fitted onto the waist area.

5. The absorbable plugging system according to claim 4, characterized in that, The fixing component is a flexible sleeve or a ring-shaped coil.

6. The absorbable plugging system according to claim 3, characterized in that, The sealing disc is formed by braiding filaments and includes a proximal disc surface, a distal disc surface, and a ridge connecting the proximal disc surface and the distal disc surface. The braiding density of the ridge is greater than the braiding density of the proximal disc surface and the braiding density of the distal disc surface.

7. The absorbable plugging system according to claim 1, characterized in that, The first adhesive part and the second adhesive part form an adhesive tape buckle; or, the first adhesive part and the second adhesive part form a snap fastener.

8. The absorbable plugging system according to claim 1, characterized in that, The sealing frame includes multiple braided filaments and multiple fiber strands, all made of absorbable material, and the multiple braided filaments and multiple fiber strands are woven together in an intersecting manner to form a mesh structure.

9. The absorbable plugging system according to claim 1, characterized in that, The material of the sealing frame is selected from at least one of polylactic acid, polyglycolic acid, polylactic acid-glycolic acid copolymer, polyhydroxy fatty acid ester, polydioxanone, polycaprolactone, polygluconic acid, polyhydroxybutyric acid, polyanhydride, polyphosphate, polydioxanone, and polycarbonate.

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