Sweeping control method and related device

Abstract

An embodiment of the present invention provides a sweep control method and related device, which relate to the field of electronic instruments. By obtaining the initial output voltage values corresponding to different frequency bands to be swept by the digital-to-analog conversion module and the sweep frequency ranges corresponding to different frequency bands to be swept by the sine wave generation module, according to the initial output voltage values corresponding to each frequency band to be swept, controlling the digital-to-analog conversion module to output voltage signals with different amplitudes; according to the sweep frequency ranges corresponding to each frequency band to be swept, controlling the sine wave generation module to output sine wave carrier signals with different frequencies; by obtaining the current value of the signal amplification circuit collected in real time, determining the frequency of the sine wave carrier signal corresponding to the minimum current value, and further determining the resonant frequency with the minimum energy consumption corresponding to the frequency band to be swept. In this way, for radio frequency ion transmission quadrupoles with different equivalent capacitances, resonance frequency scanning in different frequency bands can be achieved, with good fast self-adaptability and stability, greatly expanding the application field of quadrupole mass spectrometers.

Description

Technical Field

[0001] The present invention relates to the field of electronic instruments, and in particular, to a sweep frequency control method and related device. Background Art

[0002] Mass spectrometers are mainly divided into ion trap mass spectrometers, quadrupole mass spectrometers, time-of-flight mass spectrometers, magnetic cyclotron resonance mass spectrometers, orbitrap mass spectrometers, etc. according to the mass analyzer. Among them, the quadrupole mass spectrometer is widely used as a transmission quadrupole in the ion transmission of the atmospheric pressure interface in addition to being used as a mass analyzer. The transmission quadrupole usually applies a radio frequency electric field of a certain frequency. Ions move continuously under the action of the electric field and collide with the background gas, and finally the ion state is cooled to enter the mass analyzer in a more stable state.

[0003] Usually, the frequency of the drive circuit of the transmission quadrupole is relatively fixed, fluctuating around the fixed frequency, and the adjustable range is narrow. However, due to different factors such as the material, structural dimensions, medium, and field diameter of the transmission quadrupole, the capacitance values are different, and different radio frequency circuits are required for resonance point matching; at the same time, under the condition that the inner diameter of the transmission quadrupole field remains unchanged and the radio frequency amplitude is the same, when analyzing the stable region of the transmission quadrupole, ions with small mass numbers usually require a high-frequency electric field for transmission, and ions with large mass numbers are more suitable for a low-frequency radio frequency electric field. Based on the adaptation of different transmission structures to the tolerance value range and the ion transmission requirements of a wide mass range, to achieve an extremely wide range from a low equivalent capacitance to a high equivalent capacitance for the transmission quadrupole, especially to achieve different resonance frequency scans in different frequency bands as well as the adaptability and stability, there is no mature method or solution yet, and the application field of the instrument is also greatly limited. Summary of the Invention

[0004] In view of this, the purpose of the present invention is to provide a sweep frequency control method and related device to achieve resonance frequency scanning in different frequency bands for a quadrupole mass spectrometer with a radio frequency ion transmission quadrupole having different equivalent capacitances.

[0005] To achieve the above purpose, the technical solutions adopted in the embodiments of the present invention are as follows:

[0006] In a first aspect, the present invention provides a sweep frequency control method, which is applied to the main control module of a quadrupole power supply circuit. The quadrupole power supply circuit further includes a sine wave generation module, a digital-to-analog conversion module, and a current sampling module. The sine wave generation module, the digital-to-analog conversion module, and the current sampling module are all electrically connected to the main control module. The sine wave generation module and the digital-to-analog conversion module are electrically connected to the transmission quadrupole through a signal amplification circuit, and the current sampling module is electrically connected to the signal amplification circuit; the method includes:

[0007] Obtain the initial output voltage values corresponding to different frequency bands to be scanned by the digital-to-analog conversion module and the frequency sweep ranges corresponding to different frequency bands to be scanned by the sine wave generation module;

[0008] According to the initial output voltage value corresponding to each frequency band to be scanned, control the digital-to-analog conversion module to output voltage signals with different amplitudes; and, according to the frequency sweep range corresponding to each frequency band to be scanned, control the sine wave generation module to output sine wave carrier signals with different frequencies; wherein, the sine wave carrier signal and the voltage signal are amplified by the signal amplification circuit and then transmitted to the transmission quadrupole;

[0009] Obtain the current value of the signal amplification circuit collected in real time by the current sampling module, and determine the minimum current value based on the obtained multiple current values;

[0010] According to the frequency of the sine wave carrier signal corresponding to the minimum current value, determine the resonant frequency with the minimum energy consumption corresponding to the frequency band to be scanned.

[0011] In an optional implementation manner, the frequency sweep range corresponding to each frequency band to be scanned includes a start frequency and an end frequency. The controlling the digital-to-analog conversion module to output voltage signals with different amplitudes according to the initial output voltage value corresponding to each frequency band to be scanned; and, controlling the sine wave generation module to output sine wave carrier signals with different frequencies according to the frequency sweep range corresponding to each frequency band to be scanned includes:

[0012] For each frequency band to be scanned, when performing the first frequency sweep, control the digital-to-analog conversion module to output a voltage signal with an amplitude of the initial output voltage value, and control the sine wave generation module to output a sine wave carrier signal with a frequency of the start frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to a set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is the end frequency;

[0013] After each frequency sweep is completed, if the number of frequency sweeps of the frequency band to be scanned reaches a preset number, end the frequency sweep operation for the frequency band to be scanned; if the number of frequency sweeps of the frequency band to be scanned does not reach the preset number, determine a new start frequency and a new end frequency according to the frequency sweep result of the most recent frequency sweep;

[0014] When performing the next frequency sweep, increase the amplitude of the voltage signal output by the digital-to-analog conversion module, and control the sine wave generation module to output a sine wave carrier signal with a frequency of the new starting frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to a new set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is the new ending frequency. In an alternative embodiment, the frequency sweep result of the most recent frequency sweep includes a plurality of current values collected by the current sampling module during the most recent frequency sweep and the frequency of the sine wave carrier signal corresponding to each current value;

[0015] Determining the new starting frequency and the new ending frequency according to the frequency sweep result of the most recent frequency sweep includes:

[0016] From the frequency sweep result of the most recent frequency sweep, determine the two smallest current values collected by the current sampling module and the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively; according to the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively, determine a new frequency sweep range; the new frequency sweep range includes a new starting frequency and a new ending frequency;

[0017] In an alternative embodiment, obtaining the current value of the signal amplification circuit collected by the current sampling module in real time and determining the minimum current value based on the obtained multiple current values includes:

[0018] Obtain a plurality of current values of the signal amplification circuit collected by the current sampling module during the last frequency sweep in the frequency band to be swept, and determine the minimum current value among the plurality of current values.

[0019] In an alternative embodiment, determining the resonant frequency with the minimum energy consumption corresponding to the frequency band to be swept according to the frequency of the sine wave carrier signal corresponding to the minimum current value includes:

[0020] If the frequency of the sine wave carrier signal corresponding to the minimum current value is within the frequency sweep range corresponding to the frequency band to be swept, then determine the frequency of the sine wave carrier signal corresponding to the minimum current value as the resonant frequency with the minimum energy consumption corresponding to the frequency band to be swept.

[0021] In an alternative embodiment, the current sampling module includes an analog-to-digital conversion module and a filtering module. The analog-to-digital conversion module is electrically connected to the signal amplification circuit, and the filtering module is electrically connected to both the analog-to-digital conversion module and the main control module; obtaining the current value of the signal amplification circuit collected by the current sampling module in real time includes:

[0022] The current value of the signal amplification circuit is collected by the modulo transformation module to obtain an initial current value;

[0023] The initial current value is filtered by the filtering module to obtain the current value of the signal amplification circuit.

[0024] In a second aspect, the present invention provides a sweep frequency control device applied to a main control module of a quadrupole power supply circuit. The quadrupole power supply circuit further includes a sine wave generation module, a digital-to-analog transformation module, and a current sampling module. The sine wave generation module, the digital-to-analog transformation module, and the current sampling module are all electrically connected to the main control module. The sine wave generation module and the digital-to-analog transformation module are electrically connected to a transmission quadrupole through a signal amplification circuit, and the current sampling module is electrically connected to the signal amplification circuit; the device includes:

[0025] A parameter acquisition module for acquiring the initial output voltage value corresponding to the digital-to-analog transformation module in different frequency bands to be swept and the sweep frequency range corresponding to the sine wave generation module in different frequency bands to be swept;

[0026] A sweep frequency control module for controlling the digital-to-analog transformation module to output voltage signals with different amplitudes according to the initial output voltage value corresponding to each frequency band to be swept; and, controlling the sine wave generation module to output sine wave carrier signals with different frequencies according to the sweep frequency range corresponding to each frequency band to be swept; wherein, the sine wave carrier signal and the voltage signal are amplified by the signal amplification circuit and then transmitted to the transmission quadrupole;

[0027] A current value determination module for acquiring the current value of the signal amplification circuit collected by the current sampling module in real time and determining the minimum current value based on the acquired multiple current values;

[0028] A resonance frequency determination module for determining the resonance frequency with the minimum energy consumption corresponding to the frequency band to be swept according to the frequency of the sine wave carrier signal corresponding to the minimum current value.

[0029] In a third aspect, the present invention provides a quadrupole power supply circuit, including a main control module, a sine wave generation module, a digital-to-analog transformation module, and a current sampling module. The sine wave generation module, the digital-to-analog transformation module, and the current sampling module are all electrically connected to the main control module. The sine wave generation module and the digital-to-analog transformation module are electrically connected to a transmission quadrupole through a signal amplification circuit, and the current sampling module is electrically connected to the signal amplification circuit;

[0030] The main control module realizes the steps of the sweep frequency control method as described in any one of the foregoing embodiments by executing a computer program.

[0031] Fourthly, the present invention provides a quadrupole mass spectrometer, including a transmission quadrupole and the quadrupole power supply circuit described in the foregoing embodiments.

[0032] Fifthly, the present invention provides a computer-readable storage medium, on which a computer program is stored. When the computer program is executed by the main control module, the steps of the frequency-sweeping control method described in any one of the foregoing embodiments are implemented.

[0033] For the frequency-sweeping control method and related devices provided by the embodiments of the present invention, the main control module obtains the initial output voltage values corresponding to different frequency bands to be swept by the digital-to-analog conversion module and the frequency-sweeping ranges corresponding to different frequency bands to be swept by the sine wave generation module, and controls the digital-to-analog conversion module to output voltage signals with different amplitudes according to the initial output voltage values corresponding to each frequency band to be swept; and controls the sine wave generation module to output sine wave carrier signals with different frequencies according to the frequency-sweeping ranges corresponding to each frequency band to be swept; obtains the current values of the signal amplification circuit collected by the current sampling module in real time, and determines the minimum current value based on the obtained multiple current values; and determines the resonance frequency with the minimum energy consumption corresponding to the frequency band to be swept according to the frequency of the sine wave carrier signal corresponding to the minimum current value. In this way, for a quadrupole mass spectrometer with a radio frequency ion transmission quadrupole having different equivalent capacitances, the resonance frequency scanning of different frequency bands can be realized, with good fast self-adaptability and stability, greatly expanding the application field of the quadrupole mass spectrometer.

[0034] To make the above objects, features, and advantages of the present invention more obvious and understandable, the following specifically enumerates preferred embodiments and, in conjunction with the accompanying drawings, makes a detailed description as follows. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] To more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required in the embodiments. It should be understood that the following drawings only show some embodiments of the present invention, and therefore should not be regarded as limiting the scope. For those of ordinary skill in the art, other related drawings can be obtained based on these drawings without creative efforts.

[0036] Figure 1 Shows a structural block diagram of a quadrupole mass spectrometer provided by an embodiment of the present invention;

[0037] Figure 2 Shows a schematic flow chart of a frequency-sweeping control method provided by an embodiment of the present invention;

[0038] Figure 3 Shows another schematic flow chart of a frequency-sweeping control method provided by an embodiment of the present invention;

[0039] Figure 4Shows another structural block diagram of the quadrupole mass spectrometer provided by the embodiments of the present invention;

[0040] Figure 5 Shows another schematic flowchart of the sweep frequency control method provided by the embodiments of the present invention;

[0041] Figure 6 Shows a functional module diagram of the sweep frequency control device provided by the embodiments of the present invention.

[0042] Icons: 10 - quadrupole mass spectrometer; 100 - quadrupole power supply circuit; 200 - transmission quadrupole; 300 - signal amplification circuit; 700 - sweep frequency control device; 110 - main control module; 120 - sine wave generation module; 130 - digital - to - analog conversion module; 140 - current sampling module; 141 - analog - to - digital conversion module; 142 - filtering module; 710 - parameter acquisition module; 720 - sweep frequency control module; 730 - current value determination module; 740 - resonance frequency determination module. Detailed implementation manners

[0043] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Usually, the components of the embodiments of the present invention described and shown in the accompanying drawings here can be arranged and designed in various different configurations.

[0044] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed present invention, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative efforts fall within the scope of protection of the present invention.

[0045] It should be noted that relational terms such as "first" and "second" are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variant thereof are intended to cover non - exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "including one..." does not exclude the existence of additional identical elements in the process, method, article or device including the said element.

[0046] Please refer to Figure 1, which is a structural block diagram of a quadrupole mass spectrometer 10 provided by an embodiment of the present invention. The quadrupole mass spectrometer 10 includes a quadrupole power supply circuit 100 and a transmission quadrupole 200. The quadrupole power supply circuit 100 includes a main control module 110, a sine wave generation module 120, a digital-to-analog conversion module 130, and a current sampling module 140. The sine wave generation module 120, the digital-to-analog conversion module 130, and the current sampling module 140 are all electrically connected to the main control module 110. The sine wave generation module 120 and the digital-to-analog conversion module 130 are electrically connected to the transmission quadrupole 200 through a signal amplification circuit 300, and the current sampling module 140 is electrically connected to the signal amplification circuit 300.

[0047] In this embodiment, the main control module 110 can be an MCU (Microcontroller Unit), the sine wave generation module 120 can be a DDS sine wave signal generator, and the digital-to-analog conversion module 130 is a high-speed D / A conversion module. The main control module 110 can control the sine wave generation module 120 to generate sine wave carrier signals with different frequency magnitudes in different frequency bands. The main control module 110 can also control the digital-to-analog conversion module 130 to perform RF high-voltage amplitude control and perform real-time current value sampling through the current sampling module 140.

[0048] In this embodiment, the main control module 110 can implement the frequency sweep control method disclosed in the embodiment of the present invention by executing a computer program. Specifically, when the main control module 110 is working, the sine wave carrier signal generated by the sine wave generation module 120 and the voltage signal output by the digital-to-analog conversion module 130 are output to the signal amplification circuit 300 for amplification processing, and then output to the transmission quadrupole 200; the current sampling module 140 continuously samples the current value of the signal amplification circuit 300, and the main control module 110 finds the frequency corresponding to the minimum current value, so as to quickly and accurately scan the resonant frequency with the minimum energy consumption.

[0049] It should be understood that Figure 1 The structure shown is only a schematic structural diagram of the quadrupole mass spectrometer 10. In practical applications, the quadrupole mass spectrometer 10 may also include more or fewer components than those shown in Figure 1 or have a configuration different from that shown in Figure 1 . Figure 1 Each component shown in

[0050] Below, based on the structure of the quadrupole mass spectrometer 10 shown in Figure 1 the frequency sweep control method provided by the embodiment of the present invention will be described in detail.

[0051] Please refer to Figure 2, which is a schematic flowchart of a frequency sweep control method provided by an embodiment of the present invention. It should be noted that the frequency sweep control method of the embodiment of the present invention is not limited to Figure 2 and the following specific order. It should be understood that in other embodiments, the order of some steps of the frequency sweep control method of the embodiment of the present invention can be interchanged according to actual needs, or some of the steps can also be omitted or deleted. This frequency sweep control method can be applied to Figure 1 the main control module 110 of the quadrupole power supply circuit 100 shown in Figure 2 The specific process shown will be elaborated in detail below.

[0052] Step S201, obtain the initial output voltage values corresponding to different frequency sweep bands of the digital-to-analog conversion module and the frequency sweep ranges corresponding to different frequency sweep bands of the sine wave generation module.

[0053] In an example, the low-frequency band, the middle-frequency band, and the high-frequency band can be divided as different frequency sweep bands, and the initial output voltages and frequency sweep ranges corresponding to the low-frequency band, the middle-frequency band, and the high-frequency band are preset in the main control module 110.

[0054] For example, the frequency sweep range corresponding to the low-frequency band is FO1~FE1, and the initial output voltage corresponding to the low-frequency band scan is V1; the frequency sweep range corresponding to the middle-frequency band is FO2~FE2, and the initial output voltage corresponding to the middle-frequency band scan is V2; the frequency sweep range corresponding to the high-frequency band is FO3~FE3, and the initial output voltage corresponding to the high-frequency band scan is V3.

[0055] After the system initialization starts, the main control module 110 will start to work and obtain the initial output voltage values corresponding to different frequency sweep bands of the preset digital-to-analog conversion module 130 and the frequency sweep ranges corresponding to different frequency sweep bands of the sine wave generation module 120.

[0056] Step S202, control the digital-to-analog conversion module to output voltage signals with different amplitudes according to the initial output voltage values corresponding to each frequency sweep band; and, control the sine wave generation module to output sine wave carrier signals with different frequencies according to the frequency sweep ranges corresponding to each frequency sweep band; wherein, the sine wave carrier signals and the voltage signals are amplified by the signal amplification circuit and then transmitted to the transmission quadrupole.

[0057] In this embodiment, when multiple frequency sweep bands are preset in the system, the scan order of the multiple frequency sweep bands can be correspondingly set. For example, for the three frequency sweep bands of the low-frequency band, the middle-frequency band, and the high-frequency band, they can be scanned in the order of the low-frequency band, the middle-frequency band, and the high-frequency band, or in the order of the high-frequency band, the middle-frequency band, and the low-frequency band, and no specific limitation is made thereto.

[0058] Among them, when the main control module 110 controls the sine wave generation module 120 to output sine wave carrier signals with different frequencies according to the frequency sweep range corresponding to each frequency band to be swept, it can perform cyclic cumulative frequency sweep by continuously adjusting the frequency sweep step of the sine wave generation module 120, so that the sine wave generation module 120 outputs sine wave carrier signals with different frequencies within the frequency band to be swept. When the main control module 110 controls the digital-to-analog conversion module 130 to output voltage signals with different amplitudes according to the initial output voltage value corresponding to each frequency band to be swept, it can increase the output voltage amplitude of the digital-to-analog conversion module 130 before each next frequency sweep, thereby realizing the control of the radio frequency high voltage amplitude.

[0059] Step S203: Obtain the current value of the signal amplification circuit collected by the current sampling module in real time, and determine the minimum current value based on the obtained multiple current values.

[0060] In this embodiment, since the sine wave carrier signal generated by the sine wave generation module 120 and the voltage signal output by the digital-to-analog conversion module 130 are output to the signal amplification circuit 300 for amplification processing together, and under the control of the main control module 110, the frequency of the sine wave carrier signal and the amplitude of the voltage signal will change continuously. Furthermore, the current sampling module 140 will collect multiple current values on the signal amplification circuit 300 during the frequency sweep process, and determine the minimum current value based on the obtained multiple current values.

[0061] Step S204: Determine the resonance frequency with the minimum energy consumption corresponding to the frequency band to be swept according to the frequency of the sine wave carrier signal corresponding to the minimum current value.

[0062] In this embodiment, every time the main control module 110 obtains a current value, it will record the frequency of the sine wave carrier signal corresponding to the current value. After determining the minimum current value, it can find the frequency of the sine wave carrier signal corresponding to the minimum current value based on the minimum current value, and then determine the resonance frequency with the minimum energy consumption corresponding to the frequency band to be swept. That is to say, during the frequency sweep process, the current sampling module 140 will continuously sample and store multiple current values on the signal amplification circuit 300, and the main control module 110 reads and compares the multiple current values, and finally finds the frequency corresponding to the minimum current value, so as to scan out the resonance frequency with the minimum energy consumption quickly and accurately.

[0063] It can be seen that in the frequency sweep control method provided by the embodiment of the present invention, the main control module obtains the initial output voltage value corresponding to the digital-to-analog conversion module in different frequency bands to be swept and the frequency sweep range corresponding to the sine wave generation module in different frequency bands to be swept. According to the initial output voltage value corresponding to each frequency band to be swept, the main control module controls the digital-to-analog conversion module to output voltage signals with different amplitudes; and, according to the frequency sweep range corresponding to each frequency band to be swept, the main control module controls the sine wave generation module to output sine wave carrier signals with different frequencies. By obtaining the current value of the signal amplification circuit collected by the current sampling module in real time and determining the minimum current value based on the obtained multiple current values; and according to the frequency of the sine wave carrier signal corresponding to the minimum current value, the resonant frequency with the minimum energy consumption corresponding to the frequency band to be swept is determined. In this way, for a quadrupole mass spectrometer with a radio frequency ion transmission quadrupole having different equivalent capacitances, frequency sweep of the resonant frequency in different frequency bands can be realized, with good fast self-adaptability and stability, greatly expanding the application field of the quadrupole mass spectrometer.

[0064] Optionally, please refer to Figure 3 , the frequency sweep range corresponding to each frequency band to be swept includes a starting frequency and an ending frequency, and the above step S202 may include:

[0065] Sub-step S2021, for each frequency band to be swept, when performing the first frequency sweep, control the digital-to-analog conversion module to output a voltage signal with an amplitude equal to the initial output voltage value, and control the sine wave generation module to output a sine wave carrier signal with a frequency equal to the starting frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to a set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is equal to the ending frequency.

[0066] Sub-step S2022, after each frequency sweep is completed, if the number of frequency sweeps of the frequency band to be swept reaches a preset number, then end the frequency sweep operation for the frequency band to be swept; if the number of frequency sweeps of the frequency band to be swept does not reach the preset number, then determine a new starting frequency and a new ending frequency according to the frequency sweep result of the most recent frequency sweep.

[0067] In this embodiment, the most recent frequency sweep can be understood as the most recent frequency sweep operation; for example, after the first frequency sweep is completed, the most recent frequency sweep is the first frequency sweep; after the second frequency sweep is completed, the most recent frequency sweep is the second frequency sweep.

[0068] For the number of sweeps for each frequency band to be swept, it can be set according to actual needs. For example, if the preset number is set to 4, after the first sweep is completed and the number of sweeps for the frequency band to be swept has not reached 4 times, a new starting frequency and a new ending frequency are determined based on the sweep result of the first sweep, so as to enter the next sweep of the frequency band to be swept; when the fourth sweep is completed and the number of sweeps for the frequency band to be swept has reached 4 times, the sweep operation for this frequency band to be swept will end. If there are other frequency bands to be swept, the sweep operation for other frequency bands will be entered.

[0069] Sub-step S2023, when performing the next sweep, increase the amplitude of the voltage signal output by the digital-to-analog conversion module, and control the sine wave generation module to output a sine wave carrier signal with a frequency of the new starting frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to the new set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is the new ending frequency.

[0070] That is to say, in different sweeps of the same frequency band to be swept, when entering the next sweep each time, the amplitude of the voltage signal output by the digital-to-analog conversion module 130 will be increased. For example, on the basis of the amplitude of the voltage signal output by the digital-to-analog conversion module 130 in the previous sweep, a preset value is added, and the value of this preset value is set according to the actual situation; for the frequency control of the sine wave carrier signal output by the sine wave generation module 120, it starts from the new starting frequency and is continuously accumulated according to the new set step size until the frequency of the output sine wave carrier signal reaches the new ending frequency. Among them, the step size used for each sweep can be set according to actual needs, and this embodiment does not limit this.

[0071] For example, assume that the sweep range corresponding to a certain frequency band to be swept is from the starting frequency FO1 to the ending frequency FE1, the number of sweeps corresponding to the frequency band to be swept is set to 2 (i.e., the preset number is 2), the set step size for the first sweep is Step1, the set step size for the second sweep is Step2, and the initial output voltage value of the digital-to-analog conversion module 130 corresponding to this frequency band to be swept is V1. Then when performing the first sweep, the main control module 110 will control the digital-to-analog conversion module 130 to output a voltage signal with an amplitude of V1, and control the sine wave generation module 120 to start cyclic accumulation and sweep from the starting frequency FO1 to the ending frequency FE1 with Step1 as the step size. After the first sweep is completed, a new starting frequency Fm1 and a new ending frequency Fsm1 are determined according to the sweep result of the first sweep. When performing the second sweep, increase the amplitude of the voltage signal output by the digital-to-analog conversion module 130 (for example, add a preset value A on the basis of V1), and control the sine wave generation module 120 to start cyclic accumulation and sweep from the new starting frequency Fm1 to the new ending frequency Fsm1 with Step2 as the step size.

[0072] Optionally, step S203 above may specifically include: obtaining multiple current values of the signal amplification circuit collected by the current sampling module during the last frequency sweep in the frequency band to be swept, and determining the minimum current value among the multiple current values.

[0073] That is to say, in the case of performing multiple frequency sweep operations on each frequency band to be swept, the main control module 110 can obtain multiple current values of the signal amplification circuit 300 collected by the current sampling module 140 during the last frequency sweep in the frequency band to be swept. By comparing these multiple current values, the minimum current value is finally found, and then the frequency corresponding to the minimum current value is determined, so as to achieve high-speed and accurate scanning of the resonant frequency with the minimum energy consumption.

[0074] It can be seen that the frequency sweep control method provided by the embodiment of the present invention adopts a high-speed scanning program algorithm with fine steps in a wide frequency range, adjusts the frequency output of the sine wave generation module and the voltage output of the digital-to-analog conversion module. At different frequency bands, for radio frequency quadrupoles with different equivalent capacitances, it can achieve frequency sweeping of extremely wide radio frequency resonance point frequencies from low equivalent capacitance to high equivalent capacitance, from low frequency band to high frequency band, and has good fast self-adaptability. And for each frequency band to be swept, after each frequency sweep operation is completed, a new starting frequency and a new ending frequency are re-determined. When entering the next frequency sweep, by increasing the voltage amplitude of the digital-to-analog conversion module and controlling the sine wave generation module to perform frequency sweep operations according to the new starting frequency and the new ending frequency, after multiple frequency sweeps, the frequency corresponding to the minimum current value detected during the last frequency sweep is determined as the resonant frequency with the minimum energy consumption corresponding to the frequency band to be swept. In this way, more accurate scanning of the resonant frequency with the minimum power consumption is achieved.

[0075] Optionally, the frequency sweep result of the most recent frequency sweep above may include multiple current values collected by the current sampling module 140 during the most recent frequency sweep and the frequency of the sine wave carrier signal corresponding to each current value; on this basis, the main control module 110 determines the new starting frequency and the new ending frequency according to the frequency sweep result of the most recent frequency sweep, which may specifically include:

[0076] Determining the two smallest current values collected by the current sampling module from the frequency sweep result of the most recent frequency sweep, and determining the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively; determining a new frequency sweep range according to the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively; the new frequency sweep range includes the new starting frequency and the new ending frequency.

[0077] Still taking the frequency sweep range corresponding to the frequency band to be swept as an example, starting from the starting frequency FO1 to the ending frequency FE1, after the first frequency sweep is completed (i.e., after sweeping to the ending frequency FE1), the main control module 110 can find the two smallest current values, namely the minimum current value and the second smallest current value (equal to or only slightly larger than the minimum current value) according to the magnitudes of the multiple current values obtained during the first frequency sweep. According to the frequencies corresponding to each current value recorded previously, the frequencies of the sine wave carrier signals corresponding to the two smallest current values, Fm1 and Fsm1, can be determined. Compare the magnitudes of Fm1 and Fsm1. If Fsm1 is greater than Fm1, the new frequency sweep range is determined to be Fm1 to Fsm1, where Fm1 is the new starting frequency and Fsm1 is the new ending frequency. If Fsm1 < Fm1, the new frequency sweep range is determined to be Fsm1 to Fm1, where Fsm1 is the new starting frequency and Fm1 is the new ending frequency.

[0078] Optionally, in practical applications, when there are errors in the connection of the transmission quadrupole 200, etc., it may cause the frequency corresponding to the finally found minimum current value not to be within the frequency sweep range corresponding to the current frequency band to be swept. Based on this, it is necessary to judge the frequency corresponding to the found minimum current value to finally determine whether the resonant frequency with the minimum energy consumption corresponding to the frequency band to be swept is found. Therefore, the above step S204 may include: if the frequency of the sine wave carrier signal corresponding to the minimum current value is within the frequency sweep range corresponding to the frequency band to be swept, the frequency of the sine wave carrier signal corresponding to the minimum current value is determined to be the resonant frequency with the minimum energy consumption corresponding to the frequency band to be swept.

[0079] That is to say, after finding the frequency of the sine wave carrier signal corresponding to the minimum current value, it is necessary to judge whether this frequency is within the frequency sweep range corresponding to the current frequency band to be swept. If so, it means that the resonant frequency matching within this frequency band to be swept has been found, and the scanning program for this frequency band to be swept ends. If not, it means that there is an error in the connection of the transmission quadrupole 200, and the scanning program for this frequency band to be swept ends.

[0080] Optionally, please refer to Figure 4 , which is another structural block diagram of the quadrupole mass spectrometer 10 provided by the embodiment of the present invention. The current sampling module 140 may include an analog-to-digital conversion module 141 and a filtering module 142. The analog-to-digital conversion module 141 is electrically connected to the signal amplification circuit 300, and the filtering module 142 is electrically connected to both the analog-to-digital conversion module 141 and the main control module 110.

[0081] Among them, the analog-to-digital conversion module 141 may be a high-speed A / D conversion module, and the filtering module 142 may be a median filtering module; the current value of the signal amplification circuit 300 collected by the analog-to-digital conversion module 141 will be filtered by the filtering module 142 to make the obtained current value more stable.

[0082] Based on this, obtaining the current value of the signal amplification circuit collected by the current sampling module in step S203 above may include: collecting the current value of the signal amplification circuit through the analog-to-digital conversion module to obtain an initial current value; filtering the initial current value through the filtering module to obtain the current value of the signal amplification circuit.

[0083] In this way, by filtering the collected initial current value through the filtering module, a very stable current sampling value can be obtained, which is beneficial to the subsequent search for the minimum current value and the corresponding frequency.

[0084] Next, taking the three frequency bands to be scanned as the low-frequency band, the middle-frequency band, and the high-frequency band respectively, and the initial output voltages and the frequency sweep ranges corresponding to the low-frequency band, the middle-frequency band, and the high-frequency band are V1, V2, and V3, the starting frequency FO1 to the ending frequency FE1, the starting frequency FO2 to the ending frequency FE2, and the starting frequency FO3 to the ending frequency FE3 respectively, a specific example of the content of each of the above steps is given.

[0085] Please refer to Figure 5 , assuming that each frequency band to be scanned needs to be swept twice. First, start the frequency sweep process of the low-frequency band. During the first frequency sweep, the main control module 110 controls the amplitude of the voltage signal output by the digital-to-analog conversion module 130 to be V1, and controls the sine wave generation module 120 to start cyclic cumulative frequency sweep from the starting frequency FO1 with Step1 as the step size to the ending frequency FE1. During the first frequency sweep process, the analog-to-digital conversion module 141 continuously samples N current values and transmits them to the filtering module 142 for filtering and storage. The main control module 110 cyclically searches for the minimum current value and the second minimum current value in the filtering module 142. When the minimum current value and the second minimum current value have been found, the corresponding actual frequencies: Fm1 and Fsm1 are read. If Fsm1 is greater than Fm1, the starting frequency of the second frequency sweep is Fm1, and the ending frequency is Fsm1; otherwise, vice versa. Taking Fsm1 being greater than Fm1 as an example, when the second frequency sweep is performed, the voltage output of the digital-to-analog conversion module 130 is increased on the basis of the initial output voltage value V1 (not shown in the figure). The sine wave generation module 120 starts cyclic cumulative frequency sweep from the starting frequency Fm1 with Step2 as the step size to the ending frequency Fsm1. The analog-to-digital conversion module 141 continuously samples N current values and transmits them to the filtering module 142 for filtering and storage, and cyclically searches for the minimum current value in the filtering module 142. When the minimum current value has been found, the actual frequency value corresponding to the minimum current value is read. It is judged whether the actual frequency value is within the low-frequency band range. If so, it means that the resonant frequency matching within the low-frequency band has been found, and the low-frequency band frequency sweep program ends. If not, it means that there is an error in the connection of the transmission quadrupole 200, and the low-frequency band frequency sweep program ends.

[0086] Immediately afterwards, the frequency sweep process in the intermediate frequency band begins. During the first frequency sweep, the main control module 110 controls the amplitude of the voltage signal output by the digital-to-analog conversion module 130 to be V2, and controls the sine wave generation module 120 to start cyclic cumulative frequency sweeping from the starting frequency FO2 with Step1 as the step size until the ending frequency FE2. During the first frequency sweep process, the analog-to-digital conversion module 141 continuously samples N current values and transmits them to the filtering module 142 for filtering and storage. The main control module 110 cyclically searches for the minimum current value and the second minimum current value in the filtering module 142. When the minimum current value and the second minimum current value have been found, the corresponding actual frequencies: Fm2 and Fsm2 are read. If Fsm2 is greater than Fm2, the starting frequency of the second frequency sweep is Fm2 and the ending frequency is Fsm2; otherwise, vice versa. Taking Fsm2 being greater than Fm2 as an example, when the second frequency sweep is performed, the voltage output of the digital-to-analog conversion module 130 is increased based on the initial output voltage value V2 (not shown in the figure). The sine wave generation module 120 starts cyclic cumulative frequency sweeping from the starting frequency Fm2 with Step2 as the step size until the ending frequency Fsm2. The analog-to-digital conversion module 141 continuously samples N current values and transmits them to the filtering module 142 for filtering and storage, and cyclically searches for the minimum current value in the filtering module 142. When the minimum current value has been found, the actual frequency value corresponding to the minimum current value is read. It is judged whether the actual frequency value is within the intermediate frequency band range. If so, it indicates that the resonant point frequency matching within the intermediate frequency band has been found and the intermediate frequency band frequency scanning program ends. If not, it indicates that there is an error in the load connection of the transmission quadrupole 200 and the intermediate frequency band frequency scanning program ends.

[0087] Finally, the frequency sweep process in the high-frequency band starts. During the first frequency sweep, the main control module 110 controls the amplitude of the voltage signal output by the digital-to-analog conversion module 130 to be V3, and controls the sine wave generation module 120 to start cyclic cumulative frequency sweep from the starting frequency FO3 with Step1 as the step size until the ending frequency FE3. During the first frequency sweep process, the analog-to-digital conversion module 141 continuously samples N current values and transmits them to the filtering module 142 for filtering and storage. The main control module 110 cyclically searches for the minimum current value and the second minimum current value in the filtering module 142. When the minimum current value and the second minimum current value have been found, the corresponding actual frequencies: Fm3 and Fsm3 are read. If Fsm3 is greater than Fm3, the starting frequency of the second frequency sweep is Fm3, and the ending frequency is Fsm3; otherwise, vice versa. Taking Fsm3 being greater than Fm3 as an example, when performing the second frequency sweep, the voltage output of the digital-to-analog conversion module 130 is increased on the basis of the initial output voltage value V3 (not shown in the figure). The sine wave generation module 120 starts cyclic cumulative frequency sweep from the starting frequency Fm3 with Step2 as the step size until the ending frequency Fsm3. The analog-to-digital conversion module 141 continuously samples N current values and transmits them to the filtering module 142 for filtering and storage, and cyclically searches for the minimum current value in the filtering module 142. When the minimum current value has been found, the actual frequency value corresponding to the minimum current value is read. It is judged whether the actual frequency value is within the high-frequency band range. If so, it means that the resonant point frequency matching within the high-frequency band has been found, and the scanning program ends. If not, it means that there is an error in the load connection of the transmission quadrupole 200, and the scanning program ends.

[0088] Through the above process, at the moment of power-on of the quadrupole power supply circuit 100 of the quadrupole mass spectrometer 10, rapid and accurate resonant frequency scanning is achieved, and good adaptability to the transmission quadrupole 200 with different equivalent capacitances is obtained. At the same time, for ions in different frequency bands and different mass ranges, a very high RF high-voltage amplitude driving ability and a very high-stability RF high-voltage electric field can be provided, thus achieving very good ion transmission efficiency and instrument sensitivity in a wide mass range, and expanding the application field of the instrument.

[0089] To execute the corresponding steps in the above embodiments and each possible way, an implementation manner of a frequency sweep control device is given below. Please refer to Figure 6 , which is a functional module diagram of a frequency sweep control device 700 provided by an embodiment of the present invention. It should be noted that for the frequency sweep control device 700 provided in this embodiment, its basic principle and the technical effects generated are the same as those in the above embodiments. For the sake of brief description, for the parts not mentioned in this embodiment, reference can be made to the corresponding content in the above embodiments. The frequency sweep control device 700 includes a parameter acquisition module 710, a frequency sweep control module 720, a current value determination module 730, and a resonant frequency determination module 740.

[0090] The parameter acquisition module 710 is configured to acquire the initial output voltage values corresponding to different frequency bands to be scanned by the digital-to-analog conversion module and the frequency sweep ranges corresponding to different frequency bands to be scanned by the sine wave generation module.

[0091] It can be understood that the parameter acquisition module 710 can execute the above-mentioned step S201.

[0092] The frequency sweep control module 720 is configured to control the digital-to-analog conversion module to output voltage signals with different amplitudes according to the initial output voltage values corresponding to each frequency band to be scanned; and control the sine wave generation module to output sine wave carrier signals with different frequencies according to the frequency sweep ranges corresponding to each frequency band to be scanned; wherein, the sine wave carrier signals and the voltage signals are transmitted to the transmission quadrupole after being amplified by the signal amplification circuit.

[0093] It can be understood that the frequency sweep control module 720 can execute the above-mentioned step S202.

[0094] The current value determination module 730 is configured to acquire the current value of the signal amplification circuit collected in real time by the current sampling module, and determine the minimum current value based on the acquired multiple current values.

[0095] It can be understood that the current value determination module 730 can execute the above-mentioned step S203.

[0096] The resonance frequency determination module 740 is configured to determine the resonance frequency with the minimum energy consumption corresponding to the frequency band to be scanned according to the frequency of the sine wave carrier signal corresponding to the minimum current value.

[0097] It can be understood that the resonance frequency determination module 740 can execute the above-mentioned step S204.

[0098] Optionally, the frequency sweep range corresponding to each frequency band to be swept includes a start frequency and an end frequency. The frequency sweep control module 720 is configured to, for each frequency band to be swept, when performing the first frequency sweep, control the digital-to-analog conversion module to output a voltage signal with an amplitude of the initial output voltage value, and control the sine wave generation module to output a sine wave carrier signal with a frequency of the start frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to a set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is the end frequency; after each frequency sweep is completed, if the number of frequency sweeps of the frequency band to be swept reaches a preset number, then end the frequency sweep operation for the frequency band to be swept; if the number of frequency sweeps of the frequency band to be swept does not reach the preset number, then determine a new start frequency and a new end frequency according to the frequency sweep result of the most recent frequency sweep; when performing the next frequency sweep, increase the amplitude of the voltage signal output by the digital-to-analog conversion module, and control the sine wave generation module to output a sine wave carrier signal with a frequency of the new start frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to a new set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is the new end frequency.

[0099] It can be understood that the frequency sweep control module 720 can also execute the above sub-steps S2021 to S2023.

[0100] Optionally, the frequency sweep result of the most recent frequency sweep includes a plurality of current values collected by the current sampling module during the most recent frequency sweep and the frequency of the sine wave carrier signal corresponding to each current value; the frequency sweep control module 720 is specifically configured to determine, from the frequency sweep result of the most recent frequency sweep, the two smallest current values collected by the current sampling module and the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively; determine a new frequency sweep range according to the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively; the new frequency sweep range includes a new start frequency and a new end frequency.

[0101] Optionally, the current value determination module 730 is specifically configured to obtain a plurality of current values of the signal amplification circuit 300 collected by the current sampling module 140 during the last frequency sweep of the frequency band to be swept, and determine the smallest current value among the plurality of current values.

[0102] Optionally, the current sampling module 140 includes an analog-to-digital conversion module 141 and a filtering module 142. The analog-to-digital conversion module 141 is electrically connected to the signal amplification circuit 300, and the filtering module 142 is electrically connected to both the analog-to-digital conversion module 141 and the main control module 110.

[0103] The current value determination module 730 is specifically configured to collect the current value of the signal amplification circuit through the analog-to-digital conversion module to obtain the initial current value; and filter the initial current value through the filtering module to obtain the current value of the signal amplification circuit.

[0104] Optionally, the resonance frequency determination module 740 is specifically configured to, if the frequency of the sine wave carrier signal corresponding to the minimum current value is within the frequency sweep range corresponding to the frequency band to be swept, determine the frequency of the sine wave carrier signal corresponding to the minimum current value as the resonance frequency with the minimum energy consumption corresponding to the frequency band to be swept.

[0105] It can be seen that the frequency sweep control device provided by the embodiments of the present invention obtains the initial output voltage values corresponding to different frequency bands to be swept by the digital-to-analog conversion module and the frequency sweep ranges corresponding to different frequency bands to be swept by the sine wave generation module through the parameter acquisition module; controls the digital-to-analog conversion module to output voltage signals with different amplitudes according to the initial output voltage value corresponding to each frequency band to be swept; and the frequency sweep control module controls the sine wave generation module to output sine wave carrier signals with different frequencies according to the frequency sweep range corresponding to each frequency band to be swept; the current value determination module obtains the current value of the signal amplification circuit collected in real time by the current sampling module, and determines the minimum current value based on the obtained multiple current values; the resonance frequency determination module determines the resonance frequency with the minimum energy consumption corresponding to the frequency band to be swept according to the frequency of the sine wave carrier signal corresponding to the minimum current value. In this way, for a quadrupole mass spectrometer with a radio frequency ion transmission quadrupole having different equivalent capacitances, resonance frequency scanning in different frequency bands can be realized, with good fast self-adaptability and stability, greatly expanding the application field of the quadrupole mass spectrometer.

[0106] The embodiments of the present invention also provide a computer-readable storage medium, on which a computer program is stored. When the computer program is executed by the main control module 110, the frequency sweep control method disclosed in the above embodiments is implemented.

[0107] In several embodiments provided by this application, it should be understood that the disclosed devices and methods can also be implemented in other ways. The device embodiments described above are merely illustrative. For example, the flowcharts and block diagrams in the accompanying drawings show the possible architectures, functions, and operations of devices, methods, and computer program products according to multiple embodiments of the present invention. In this regard, each block in the flowchart or block diagram may represent a module, a program segment, or a part of code, and the module, program segment, or part of code contains one or more executable instructions for implementing the specified logical function. It should also be noted that in some alternative implementations, the functions marked in the blocks may occur in a different order than that marked in the accompanying drawings. For example, two consecutive blocks may actually be executed substantially in parallel, and they may sometimes be executed in the reverse order, depending on the functions involved. It should also be noted that each block in the block diagram and / or flowchart, as well as the combination of blocks in the block diagram and / or flowchart, can be implemented by a dedicated hardware-based system that performs the specified functions or actions, or can be implemented by a combination of dedicated hardware and computer instructions.

[0108] In addition, each functional module in various embodiments of the present invention may be integrated together to form an independent part, or each module may exist alone, or two or more modules may be integrated to form an independent part.

[0109] If the above functions are implemented in the form of software functional modules and sold or used as independent products, they can be stored in a computer-readable storage medium. Based on such an understanding, the technical solution of the present invention, in essence, or the part that contributes to the prior art, or a part of this technical solution, can be embodied in the form of a software product. This computer software product is stored in a storage medium and includes several instructions for causing a computer device (which may be a personal computer, a server, or a network device, etc.) to execute all or part of the steps of the methods described in various embodiments of the present invention. The aforementioned storage medium includes: various media such as USB flash drives, mobile hard disks, read-only memory (ROM), random access memory (RAM), magnetic disks, or optical discs that can store program codes.

[0110] The above is only the preferred embodiment of the present invention and is not used to limit the present invention. For those skilled in the art, the present invention can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A frequency sweep control method, characterized in that The main control module is applied to a quadrupole power supply circuit. The quadrupole power supply circuit further includes a sine wave generation module, a digital-to-analog conversion module, and a current sampling module. The sine wave generation module, the digital-to-analog conversion module, and the current sampling module are all electrically connected to the main control module. The sine wave generation module and the digital-to-analog conversion module are electrically connected to a transmission quadrupole through a signal amplification circuit, and the current sampling module is electrically connected to the signal amplification circuit; The method includes: Obtain the initial output voltage values corresponding to different frequency bands to be scanned by the digital-to-analog conversion module and the frequency sweep ranges corresponding to different frequency bands to be scanned by the sine wave generation module; According to the initial output voltage value corresponding to each frequency band to be scanned, control the digital-to-analog conversion module to output voltage signals with different amplitudes; and, according to the frequency sweep range corresponding to each frequency band to be scanned, control the sine wave generation module to output sine wave carrier signals with different frequencies; wherein, the sine wave carrier signal and the voltage signal are amplified by the signal amplification circuit and then transmitted to the transmission quadrupole; Obtain the current value of the signal amplification circuit collected in real time by the current sampling module, and determine the minimum current value based on the multiple current values obtained; According to the frequency of the sine wave carrier signal corresponding to the minimum current value, determine the resonant frequency with the minimum energy consumption corresponding to the frequency band to be scanned.

2. The method according to claim 1, wherein The frequency sweep range corresponding to each frequency band to be scanned includes a starting frequency and an ending frequency. According to the initial output voltage value corresponding to each frequency band to be scanned, control the digital-to-analog conversion module to output voltage signals with different amplitudes; And, according to the frequency sweep range corresponding to each frequency band to be scanned, controlling the sine wave generation module to output sine wave carrier signals with different frequencies includes: For each frequency band to be scanned, when performing the first frequency sweep, control the digital-to-analog conversion module to output a voltage signal with an amplitude of the initial output voltage value, and control the sine wave generation module to output a sine wave carrier signal with a frequency of the starting frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to a set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is the ending frequency; After each frequency sweep is completed, if the number of frequency sweeps of the frequency band to be scanned reaches a preset number, end the frequency sweep operation for the frequency band to be scanned; if the number of frequency sweeps of the frequency band to be scanned does not reach the preset number, determine a new starting frequency and a new ending frequency according to the frequency sweep result of the most recent frequency sweep; When performing the next frequency sweep, increase the amplitude of the voltage signal output by the digital-to-analog conversion module, and control the sine wave generation module to output a sine wave carrier signal with a frequency of the new starting frequency, and continuously increase the frequency of the sine wave carrier signal output by the sine wave generation module according to a new set step size until the frequency of the sine wave carrier signal output by the sine wave generation module is the new ending frequency.

3. The method according to claim 2, wherein The frequency sweep result of the most recent frequency sweep includes the multiple current values collected by the current sampling module during the most recent frequency sweep and the frequency of the sine wave carrier signal corresponding to each current value; Determining a new starting frequency and a new ending frequency according to the frequency sweep result of the most recent frequency sweep, includes: From the frequency sweep result of the most recent frequency sweep, determining the two smallest current values collected by the current sampling module, and the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively; According to the frequencies of the sine wave carrier signals corresponding to the two smallest current values respectively, determining a new frequency sweep range; the new frequency sweep range includes a new starting frequency and a new ending frequency.

4. The method according to claim 2, wherein Obtaining the current value of the signal amplification circuit collected by the current sampling module in real time, and determining the minimum current value based on the obtained multiple current values, includes: Obtaining multiple current values of the signal amplification circuit collected by the current sampling module during the last frequency sweep in the to-be-swept frequency band, and determining the minimum current value among the multiple current values.

5. The method according to claim 1, wherein According to the frequency of the sine wave carrier signal corresponding to the minimum current value, determining the resonance frequency with the minimum energy consumption corresponding to the to-be-swept frequency band, includes: If the frequency of the sine wave carrier signal corresponding to the minimum current value is within the frequency sweep range corresponding to the to-be-swept frequency band, determining the frequency of the sine wave carrier signal corresponding to the minimum current value as the resonance frequency with the minimum energy consumption corresponding to the to-be-swept frequency band.

6. The method according to claim 1, wherein The current sampling module includes an analog-to-digital conversion module and a filtering module. The analog-to-digital conversion module is electrically connected to the signal amplification circuit, and the filtering module is electrically connected to both the analog-to-digital conversion module and the main control module; obtaining the current value of the signal amplification circuit collected by the current sampling module in real time, includes: Collecting the current value of the signal amplification circuit through the analog-to-digital conversion module to obtain an initial current value; Performing filtering processing on the initial current value through the filtering module to obtain the current value of the signal amplification circuit.

7. A sweep control device, characterized in that, Applied to the main control module of a quadrupole power supply circuit. The quadrupole power supply circuit further includes a sine wave generation module, a digital-to-analog conversion module, and a current sampling module. The sine wave generation module, the digital-to-analog conversion module, and the current sampling module are all electrically connected to the main control module. The sine wave generation module and the digital-to-analog conversion module are electrically connected to the transmission quadrupole through a signal amplification circuit, and the current sampling module is electrically connected to the signal amplification circuit; the device includes: A parameter acquisition module, configured to acquire the initial output voltage values corresponding to different to-be-swept frequency bands by the digital-to-analog conversion module and the frequency sweep ranges corresponding to different to-be-swept frequency bands by the sine wave generation module; A frequency sweep control module, configured to control the digital-to-analog conversion module to output voltage signals with different amplitudes according to the initial output voltage values corresponding to each to-be-swept frequency band; and, control the sine wave generation module to output sine wave carrier signals with different frequencies according to the frequency sweep ranges corresponding to each to-be-swept frequency band; wherein, the sine wave carrier signal and the voltage signal are transmitted to the transmission quadrupole after being amplified by the signal amplification circuit. The current value determination module is configured to obtain the current value of the signal amplification circuit collected in real time by the current sampling module, and determine the minimum current value based on a plurality of obtained current values; The resonance frequency determination module is configured to determine the resonance frequency with the minimum energy consumption corresponding to the frequency band to be swept according to the frequency of the sine wave carrier signal corresponding to the minimum current value.

8. A quadrupole power supply circuit, characterized in that, It includes a main control module, a sine wave generation module, a digital-to-analog conversion module, and a current sampling module. The sine wave generation module, the digital-to-analog conversion module, and the current sampling module are all electrically connected to the main control module. The sine wave generation module and the digital-to-analog conversion module are electrically connected to the transmission quadrupole through a signal amplification circuit, and the current sampling module is electrically connected to the signal amplification circuit; The main control module realizes the steps of the frequency sweep control method according to any one of claims 1-6 by executing a computer program.

9. A quadrupole mass spectrometer, characterized in that, It includes a transmission quadrupole and the quadrupole power supply circuit according to claim 8.

10. A computer-readable storage medium, characterized in that, A computer program is stored on the computer-readable storage medium, and when the computer program is executed by the main control module, the steps of the frequency sweep control method according to any one of claims 1-6 are realized.

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