A bioreactor system disinfection method, system, storage medium and intelligent terminal

Abstract

The present application relates to a bioreactor system disinfection method, system, storage medium and intelligent terminal, and relates to the field of medical biotechnology. The method includes controlling the movement of a detection device to obtain telescopic length information; judging whether the telescopic length information is within a normal length range; if so, defining the pipeline position as a normal point; if not, defining the pipeline position as an abnormal point; forming a pipeline condition axis based on the combination of the normal point and the abnormal point, and establishing a movable virtual moving point on the pipeline condition axis; outputting a pit start signal and a pit end signal during the movement of the virtual moving point; determining pit quantity information based on the pit start signal and the pit end signal after the movement of the virtual moving point ends; determining the disinfection duration information corresponding to the pit quantity information based on the duration matching relationship, and controlling the disinfection device to perform disinfection operations based on the disinfection duration information. The present application has the effect of improving the overall disinfection effect of the bioreactor system.

Description

Technical Field

[0001] The present application relates to the field of medical biotechnology, and in particular to a bioreactor system disinfection method, system, storage medium and intelligent terminal. Background Art

[0002] A bioreactor system is a system used in the current pharmaceutical biotechnology R&D and production process to effectively cultivate and process microorganisms such as bacteria. It typically consists of a fermentation tank connected by corresponding piping. When raw materials need to be reacted, they are transported to the fermentation tank through the pipeline for reaction. Due to the high requirements of bioreactors, the pipelines must be sterilized and disinfected before raw materials are transported to reduce the possibility of abnormal bioreactions.

[0003] In the related art, when the pipeline needs to be sterilized, the valves at both ends of the transport pipeline are closed, and then the valves on the branch pipe connected to the steam sterilization equipment on the pipeline are controlled to open, so that steam can flow in the pipeline and form a circulation to sterilize and disinfect the inner wall of the pipeline.

[0004] Regarding the above-mentioned related technologies, the inventor believes that if the pipeline is concave inward due to external impact, the inner wall of the pipeline bulges inward to form a windward side and a leeward side. At this time, the windward side can be better affected by steam and sterilized. However, the leeward side is blocked by the windward side, so that the steam cannot act well on the leeward side. As a result, the sterilization effect of the leeward side may be poor within the specified disinfection time. Increasing the disinfection time may result in a situation where the disinfection is complete but still ineffective. Therefore, the overall disinfection effect of the bioreactor system is poor, and there is still room for improvement. Summary of the Invention

[0005] In order to improve the overall disinfection effect of a bioreactor system, the present application provides a bioreactor system disinfection method, system, storage medium and intelligent terminal.

[0006] In a first aspect, the present application provides a method for disinfecting a bioreactor system, which adopts the following technical solution:

[0007] A method for disinfecting a biological reaction system, comprising:

[0008] Obtain disinfection operation signal;

[0009] When the disinfection operation signal is consistent with the preset disinfection processing signal, the detection device mounted on the outer surface of the pipeline is controlled to move along a preset detection direction, and information on the telescopic length of the telescopic component preset on the inner side wall of the detection device and abutting against the outer surface of the pipeline is obtained;

[0010] Determine whether the length value corresponding to the telescopic length information is within a preset normal length range;

[0011] If the length value corresponding to the telescopic length information is within the normal length range, the pipeline position is defined as a normal point;

[0012] If the length value corresponding to the telescopic length information is not within the normal length range, the pipeline position is defined as an abnormal point;

[0013] A pipeline condition axis is formed based on the combination of normal points and abnormal points, and a movable virtual moving point is established on the pipeline condition axis, and the virtual moving point is controlled to move along the detection direction;

[0014] During the movement of the virtual moving point, when the virtual moving point switches from a normal point to an abnormal point, a pit start signal is output, and when the abnormal point switches to a normal point, a pit end signal is output;

[0015] After the virtual moving point finishes moving, the pit quantity information is determined according to the pit start signal and the pit end signal;

[0016] The disinfection time information corresponding to the pit quantity information is determined according to the preset time matching relationship, and the disinfection equipment is controlled to perform the disinfection operation according to the disinfection time information.

[0017] By adopting the above technical solution, a disinfection operation signal is obtained to determine whether the pipeline needs to be disinfected. When disinfection is required, the detection equipment is controlled to move to determine the depression condition on the pipeline, so that the specific depression condition on the pipeline can be known to match the corresponding disinfection time, thereby making the pipeline disinfection time reasonable to improve the overall disinfection effect of the bioreactor system.

[0018] Optionally, after the virtual moving point is moved, the bioreactor system disinfection method further includes:

[0019] The position of the virtual moving point when the pit start signal is output is defined as the start point, and the position of the virtual moving point when the pit end signal adjacent to the pit start signal in the detection direction is output is defined as the end point;

[0020] Calculate the distance information based on the starting point and the corresponding ending point;

[0021] Determine whether the distance value corresponding to the distance information is greater than a preset reference distance value;

[0022] If the distance value corresponding to the distance information is greater than the reference distance value, the road section between the start point and the end point is defined as a pothole section, and the original state of each signal is maintained;

[0023] If the distance value corresponding to the interval distance information is not greater than the reference distance value, the pit start signal outputted at the start point and the pit end signal outputted at the corresponding end point are cancelled.

[0024] By adopting the above technical solution, abnormal situations in pit detection can be eliminated, so that pit determination can be more accurate.

[0025] Optionally, after the pothole section is determined, the bioreactor system disinfection method further includes:

[0026] Determine, on the pothole section, the telescopic length information with the largest corresponding value among all telescopic length information according to a preset sorting rule, define the abnormal point corresponding to the telescopic length information as a vertex, and define the abnormal points at both ends of the pothole section as boundary points;

[0027] The road section whose vertex points to the boundary point is defined as the approved road section, and the difference between the expansion and contraction length information corresponding to adjacent abnormal points on a single approved road section is calculated to determine the difference length information, where the difference length information is the expansion and contraction length information of the abnormal point close to the vertex minus the expansion and contraction length information of the abnormal point far from the vertex;

[0028] Performing difference calculation based on adjacent difference length information to determine the change length information;

[0029] When the length value corresponding to the change length information is greater than a preset allowable change value, a mutation signal is output, and a count is performed according to the mutation signal to determine the number of mutations;

[0030] Calculating the number of pothole overlaps on the pothole section based on the two pieces of information on the number of sudden changes;

[0031] The pit quantity information is updated by performing a sum calculation based on the pit overlap quantity and the original pit quantity information.

[0032] By adopting the above technical solution, the overlapping situation of the pits can be analyzed to effectively and accurately determine the pit conditions.

[0033] Optionally, after the mutation signal is output, the bioreactor system disinfection method further includes:

[0034] The corresponding abnormal point is defined as a mutation point, and the stretching length information corresponding to the mutation point is defined as the mutation length information;

[0035] Perform difference calculation based on the mutation length information of adjacent mutation points to determine the deviation length information;

[0036] Determine whether the value corresponding to the deviation length information is greater than a preset reference deviation value;

[0037] If the value corresponding to the deviation length information is greater than the baseline deviation value, the original mutation quantity information is maintained;

[0038] If the value corresponding to the deviation length information is not greater than the reference deviation value, the value corresponding to the original mutation quantity information is controlled to be reduced by one.

[0039] By adopting the above technical solution, when the change is not obvious, it means that there is no new pit. At this time, the number of mutations is changed to make the pit situation more accurate.

[0040] Optionally, also include:

[0041] Determine the leeward section of the leeward side of the two approved sections determined by the same vertex according to the detection direction;

[0042] On the leeward section, determine the lateral length in the detection direction based on the vertex and boundary points;

[0043] The slope value is determined by calculating the extension length information of the vertex and the horizontal length;

[0044] Determine the slope value with the largest value according to the sorting rule, and determine the slope value as the upper limit value of the slope;

[0045] Determine the adjustment duration information corresponding to the upper limit of the slope according to the preset adjustment matching relationship;

[0046] The disinfection time information is updated by summing the adjusted time information and the original disinfection time information.

[0047] By adopting the above technical solution, the maximum slope value is determined to determine the difficulty of disinfection, so that the corresponding adjustment time can be matched to update and adjust the disinfection time to achieve a better disinfection effect.

[0048] Optionally, also include:

[0049] Determining whether the quantity value corresponding to the pit quantity information is greater than a preset qualified upper limit;

[0050] If the number value corresponding to the pit quantity information is not greater than the qualified upper limit, a pipeline normal signal is output;

[0051] If the quantity value corresponding to the pit quantity information is greater than the qualified upper limit, a replacement prompt signal is output, and a difference calculation is performed based on the pit quantity information and the qualified upper limit to determine the excess quantity;

[0052] The number of pits on each pipe is determined by counting the pits on each pipe;

[0053] According to the sorting rules, all single-tube pit numbers are sorted from large to small, and the single-tube pit numbers are summed up in sequence from large to small to determine the total number of multi-tube pits. When the total number of multi-tube pits is not less than the excess number, the pipeline corresponding to the summed single-tube pit number is defined as the abnormal pipeline to be replaced.

[0054] By adopting the above technical solution, when the number of pits is large, the pipes that need to be replaced can be marked to facilitate subsequent staff to accurately replace them.

[0055] Optionally, the method of sorting the number of pits of all single tubes from largest to smallest according to the sorting rule includes:

[0056] Determine whether the number of pits in a single tube is equal;

[0057] If the number of pits in a single tube is unequal, they are sorted according to size;

[0058] If the number of single-pipe pits is equal, the pipelines with the same number of single-pipe pits are defined as similar pipelines, and the pipeline with a single-pipe pit number greater than the current single-pipe pit number is defined as a disassembled pipeline;

[0059] The pipelines adjacent to similar pipelines and being dismantled are defined as easily dismantled pipelines, and the easily dismantled pipelines are counted to determine the number of easily dismantled pipelines corresponding to each similar pipeline;

[0060] Similar pipelines are sorted from largest to smallest according to the number of easily dismantled pipelines, and if the number of easily dismantled pipelines is the same, they are sorted according to the detection direction.

[0061] By adopting the above technical solution, the pipelines can be effectively sorted to facilitate subsequent replacement of the pipelines by the staff.

[0062] In a second aspect, the present application provides a bioreactor system disinfection system, which adopts the following technical solution:

[0063] A bioreactor system disinfection system, comprising:

[0064] An acquisition module is used to obtain a disinfection operation signal;

[0065] A processing module, connected to the acquisition module and the judgment module, for storing and processing information;

[0066] The judgment module is connected with the acquisition module and the processing module and is used for judging the information;

[0067] When the disinfection operation signal is consistent with the preset disinfection processing signal, the processing module controls the detection device mounted on the outer surface of the pipeline to move along a preset detection direction, and causes the acquisition module to acquire telescopic length information of the telescopic component preset on the inner side wall of the detection device and abutting against the outer surface of the pipeline;

[0068] The judging module judges whether the length value corresponding to the telescopic length information is within a preset normal length range;

[0069] If the judging module determines that the length value corresponding to the telescopic length information is within the normal length range, the processing module defines the pipeline position as a normal point;

[0070] If the judging module determines that the length value corresponding to the telescopic length information is not within the normal length range, the processing module defines the pipeline position as an abnormal point;

[0071] The processing module forms a pipeline condition axis based on the combination of normal points and abnormal points, establishes a movable virtual moving point on the pipeline condition axis, and controls the virtual moving point to move along the detection direction;

[0072] The processing module outputs a pit start signal when the virtual moving point switches from a normal point to an abnormal point during the movement of the virtual moving point, and outputs a pit end signal when the abnormal point switches to a normal point;

[0073] The processing module determines the pit quantity information according to the pit start signal and the pit end signal after the virtual moving point finishes moving;

[0074] The processing module determines the disinfection time information corresponding to the pit quantity information according to a preset time matching relationship, and controls the disinfection equipment to perform the disinfection operation according to the disinfection time information.

[0075] By adopting the above technical solution, the acquisition module obtains the disinfection operation signal to determine whether the pipeline needs to be disinfected. When disinfection is required, the processing module controls the movement of the detection equipment to determine the depression condition on the pipeline, so that the specific depression condition on the pipeline can be known so that the processing module can match the corresponding disinfection time, thereby making the pipeline disinfection time reasonable to improve the overall disinfection effect of the biological reaction system.

[0076] In a third aspect, the present application provides a smart terminal that adopts the following technical solution:

[0077] An intelligent terminal comprises a memory and a processor, wherein the memory stores a computer program which can be loaded by the processor and execute any one of the above-mentioned bioreactor system disinfection methods.

[0078] By adopting the above technical solution and using an intelligent terminal, a disinfection operation signal is obtained to determine whether the pipeline needs to be disinfected. When disinfection is required, the detection equipment is controlled to move to determine the depression condition on the pipeline, so that the specific depression condition on the pipeline can be known to match the corresponding disinfection time, thereby making the pipeline disinfection time reasonable and improving the overall disinfection effect of the bioreactor system.

[0079] In a fourth aspect, the present application provides a computer storage medium capable of storing corresponding programs, which has the characteristics of improving the overall disinfection effect of the bioreactor system, and adopts the following technical solutions:

[0080] A computer-readable storage medium stores a computer program that can be loaded by a processor and execute any of the above-mentioned bioreactor system disinfection methods.

[0081] By adopting the above technical solution, a computer program of the bioreactor system disinfection method is stored in a storage medium, and a disinfection operation signal is obtained to determine whether the pipeline needs to be disinfected. When disinfection is required, the detection equipment is controlled to move to determine the depression condition on the pipeline, so that the specific depression condition on the pipeline can be known to match the corresponding disinfection time, thereby making the pipeline disinfection time reasonable to improve the overall disinfection effect of the bioreactor system.

[0082] In summary, this application includes at least one of the following beneficial technical effects:

[0083] When the pipeline needs to be disinfected, the pit conditions of the pipeline can be analyzed to determine the more appropriate disinfection time, thereby improving the overall disinfection effect of the bioreactor system;

[0084] The overlapping of pits can be analyzed to make the number of pits determined more accurate;

[0085] When there are a large number of pits, the pipes that need to be replaced can be marked to facilitate subsequent replacement by staff. BRIEF DESCRIPTION OF THE DRAWINGS

[0086] Figure 1 It is a flow chart of the disinfection method of the biological reaction system.

[0087] Figure 2 It is a flow chart of the method for determining the pit condition.

[0088] Figure 3 It is a flowchart of the method for updating the number of pits.

[0089] Figure 4 It is a schematic diagram of the system piping situation.

[0090] Figure 5 It is a flow chart of the pit overlap analysis method.

[0091] Figure 6 It is a flow chart of the disinfection time updating method.

[0092] Figure 7 This is a flow chart of the method for replacing pipeline markings.

[0093] Figure 8 It is a flow chart of the pipeline sequencing method.

[0094] Figure 9 This is a modular flow chart of the bioreactor system disinfection method. Implementation Method

[0095] In order to make the purpose, technical solutions and advantages of this application more clear, the following Figure 1-9 It should be understood that the specific embodiments described herein are only used to explain the present application and are not intended to limit the present application.

[0096] The embodiments of the present application are described in further detail below with reference to the accompanying drawings.

[0097] An embodiment of the present application discloses a bioreactor system disinfection method. When a pipeline needs to be disinfected, a detection device is used to move on the pipeline to determine the condition of the pits on the pipeline, thereby knowing the number of pits and the slope of the leeward side of the pits, so as to match a more reasonable disinfection time to enable the disinfection equipment to operate, thereby improving the overall disinfection effect of the bioreactor system.

[0098] Reference Figure 1 The method flow of the biological reaction system disinfection method includes the following steps:

[0099] S100: Obtain a disinfection operation signal.

[0100] The disinfection operation signal is a signal that the staff needs to input to indicate whether pipeline disinfection is required.

[0101] S101: When the disinfection operation signal is consistent with the preset disinfection processing signal, the detection device mounted on the outer surface of the pipeline is controlled to move along a preset detection direction, and the telescopic length information of the telescopic component preset on the inner wall of the detection device and abutting against the outer surface of the pipeline is obtained.

[0102] The disinfection signal is a signal set by the staff to be input when the staff needs to disinfect the pipeline. The detection equipment is a device that is mounted on the outer surface of the pipeline and can move in the length direction of the pipeline. The detection direction is the direction extending along the length of the pipeline set by the staff. The telescopic component is a structure arranged on the inner ring side wall of the detection equipment and used to abut against the outer surface of the pipeline. The component is arranged at intervals along the circumference of the inner ring of the detection equipment so that it can detect various parts of the circumference of the pipeline. The component is facing the center of the detection equipment and can be telescopically arranged on the detection equipment. The component has a spring. When the end of the telescopic component is at the center of the detection equipment, the spring is in a natural state. Therefore, when the telescopic component abuts against the outer surface of the pipeline, the spring is in a compressed state. The length value corresponding to the telescopic length information is the length value of the telescopic component compared to when it abuts against the outer surface of the pipeline, that is, when the telescopic component abuts against the outer surface of the pipeline, the corresponding telescopic length is 0.

[0103] S102: Determine whether the length value corresponding to the telescopic length information is within a preset normal length range.

[0104] The normal length range is the range of telescopic length that can be determined when the staff determines that there are no pits on the pipe surface. The purpose of the judgment is to know whether there are pits on the pipe surface.

[0105] S1021: If the length value corresponding to the telescopic length information is within a normal length range, the pipeline position is defined as a normal point.

[0106] When the length value corresponding to the telescopic length information is within the normal length range, it indicates that there is no pit at the position detected by the current detection device. At this time, the position is defined as a normal point in the length direction of the pipeline for identification, so as to define and distinguish the conditions of various positions in the pipeline.

[0107] S1022: If the length value corresponding to the telescopic length information is not within the normal length range, the pipeline position is defined as an abnormal point.

[0108] When the length value corresponding to the telescopic length information is not within the normal length range, it means that there is a pit at the position detected by the current detection equipment. At this time, the position is defined as an abnormal point in the length direction of the pipeline for identification, so as to define and distinguish the conditions of various positions in the pipeline.

[0109] S103: forming a pipeline condition axis according to the combination of normal points and abnormal points, establishing a movable virtual moving point on the pipeline condition axis, and controlling the virtual moving point to move along the detection direction.

[0110] The pipeline condition axis is a linear axis formed by connecting normal points and abnormal points in series along the detection direction, which can reflect the specific conditions of each position on the pipeline. The virtual moving point is a virtual moving point on the pipeline condition axis that can be moved along the length direction, only for analysis and processing.

[0111] S104: During the movement of the virtual moving point, the virtual moving point outputs a pit start signal when the virtual moving point switches from a normal point to an abnormal point, and outputs a pit end signal when the abnormal point switches to a normal point.

[0112] When the virtual moving point switches from a normal point to an abnormal point, it means that the position to which the virtual moving point has moved has just entered a pit. At this time, a pit start signal is output to identify the situation so as to facilitate the specific analysis situation. Similarly, when the virtual moving point switches from an abnormal point to a normal point, it means that the position to which the virtual moving point has moved has just moved out of a pit. At this time, a pit end signal is output to identify the situation so as to facilitate the specific analysis situation.

[0113] S105: After the virtual moving point finishes moving, determine the pit quantity information according to the pit start signal and the pit end signal.

[0114] The quantity value corresponding to the pit quantity information is the total quantity value of all pits on the pipeline. A pit start signal and a corresponding pit end signal represent one pit, so they can be counted one by one to determine the total quantity of pits.

[0115] S106: Determine the disinfection duration information corresponding to the pit quantity information according to a preset duration matching relationship, and control the disinfection equipment to perform the disinfection operation according to the disinfection duration information.

[0116] The duration value corresponding to the disinfection duration information is the duration required for disinfection of the bioreactor system. Different numbers of pits indicate different degrees of difficulty in disinfection, so different disinfection duration information is required. The duration matching relationship between the two is determined in advance by the staff based on multiple tests. The disinfection equipment used is generally high-temperature steam equipment, with the air outlet connected to one branch of the pipeline and the air inlet connected to the other branch of the pipeline.

[0117] Reference Figure 2 After the virtual moving point is moved, the bioreactor system disinfection method further includes:

[0118] S200: The position of the virtual moving point when the pit start signal is output is defined as the start point, and the position of the virtual moving point when the pit end signal adjacent to the pit start signal in the detection direction is output is defined as the end point.

[0119] The starting point and the ending point are defined to determine the two boundary positions of the pit, so as to distinguish different abnormal points and facilitate subsequent analysis.

[0120] S201: Calculate the distance information based on the starting point and the corresponding ending point.

[0121] The distance value corresponding to the separation distance information is the distance value between the two determined boundary positions of the pit.

[0122] S202: Determine whether the distance value corresponding to the distance information is greater than a preset reference distance value.

[0123] The reference distance value is the minimum pit length set by the staff to determine whether the pit will affect the disinfection of the pipeline. The purpose of the judgment is to know whether the current pit will affect the disinfection of the pipeline.

[0124] S2021: If the distance value corresponding to the interval distance information is greater than the reference distance value, the road section between the start point and the end point is defined as a pothole section, and the original state of each signal is maintained.

[0125] When the distance value corresponding to the separation distance information is greater than the reference distance value, it indicates that the pit can affect the pipeline. In this case, the pit section is determined to define it for subsequent processing.

[0126] S2022: If the distance value corresponding to the interval distance information is not greater than the reference distance value, canceling the pit start signal outputted at the start point and the pit end signal outputted at the corresponding end point.

[0127] When the distance value corresponding to the interval distance information is not greater than the reference distance value, it means that the current pit detection is abnormal or the detected pit will not affect the pipeline. At this time, the corresponding pit start signal and the pit end signal are canceled, so that when determining the number of pits, the number of pits that have an impact can be determined more accurately, thereby eliminating errors and improving the accuracy of subsequent disinfection treatment.

[0128] Reference Figure 3 After the pothole section is determined, the bioreactor system disinfection method also includes:

[0129] S300: Determine the telescopic length information with the largest corresponding value among all telescopic length information on the pothole section according to a preset sorting rule, define the abnormal point corresponding to the telescopic length information as a vertex, and define the abnormal points at both ends of the pothole section as boundary points.

[0130] The sorting rule is a bubble method set by the staff to sort the values. For example, the bubble method can be used to determine the maximum telescopic length information on a single pothole section. At this time, the abnormal point corresponding to the telescopic length information is the point at the bottom of the pothole groove. Figure 4 , define the outlier point as a vertex for identification, so as to distinguish different outliers, and define the boundary point for subsequent analysis and processing.

[0131] S301: Define a road section whose vertex points to a boundary point as an approved road section, and calculate the difference between the telescopic length information corresponding to adjacent abnormal points on a single approved road section to determine the difference length information, wherein the difference length information is the telescopic length information of the abnormal point close to the vertex minus the telescopic length information of the abnormal point far from the vertex.

[0132] Define the approved road section to define and identify the road section from the vertex to the boundary point for subsequent analysis. The length value corresponding to the difference length information is the difference between the expansion and contraction lengths determined by adjacent outliers, which is obtained by subtracting the expansion and contraction length of the outlier close to the vertex from the outlier far from the vertex.

[0133] S302: Perform difference calculation based on adjacent difference length information to determine change length information.

[0134] The difference corresponding to the change length information is the difference between adjacent difference lengths, and the difference is an absolute value.

[0135] S303: Outputting a mutation signal when the length value corresponding to the change length information is greater than a preset allowable change value, and counting according to the mutation signal to determine mutation quantity information.

[0136] The allowable change value is the minimum change length set by the staff when the change in the telescopic length does not follow the change trend of the potholes. When the length value corresponding to the change length information is greater than the allowable change value, it means that the change trend has changed. For example, when the telescopic length gradually decreases and then increases again, it means that two potholes overlap to form a pothole section. Figure 4 At this time, a mutation signal is output to identify and record the situation. The quantity value corresponding to the mutation quantity information is the total quantity value of the mutation signals appearing in a single approved road section.

[0137] S304: Calculate the number of overlapping potholes on the pothole section based on the two pieces of information on the number of sudden changes.

[0138] The quantity value corresponding to the number of pit overlaps is the number of pits in the pit section compared to one pit. The calculation formula is, where is the quantity value corresponding to the number of pit overlaps. When the calculated value is a decimal, it is rounded down; and are the quantity values corresponding to the two mutation quantity information respectively.

[0139] S305: performing a sum calculation based on the number of pit overlaps and the original pit number information to update the pit number information.

[0140] The actual number of pits is updated according to the pit overlap situation, so that the determined pit number information is more accurate, so that the subsequent disinfection effect is better.

[0141] Reference Figure 5 After the mutation signal is output, the bioreactor system disinfection method further includes:

[0142] S400: defining the corresponding abnormal point as a mutation point, and defining the telescopic length information corresponding to the mutation point as mutation length information.

[0143] Define mutation points to identify and distinguish abnormal points for subsequent analysis and processing, and define mutation length information to facilitate subsequent data calls.

[0144] S401: performing difference calculation based on the mutation length information of adjacent mutation points to determine deviation length information.

[0145] The length value corresponding to the deviation length information is the length difference between the mutation lengths of adjacent mutation points, and the length value is an absolute value.

[0146] S402: Determine whether the value corresponding to the deviation length information is greater than a preset reference deviation value.

[0147] The baseline deviation value is the minimum deviation length set by the staff to determine that the mutation can form a pit that affects the disinfection process. The purpose of the judgment is to know that the pit is only a small change and will not affect the subsequent disinfection process.

[0148] S4021: If the value corresponding to the deviation length information is greater than the reference deviation value, the original mutation quantity information is maintained.

[0149] When the value corresponding to the deviation length information is greater than the reference deviation value, it means that the determined pit will affect the disinfection operation. In this case, the original mutation quantity information can be maintained normally.

[0150] S4022: If the value corresponding to the deviation length information is not greater than the reference deviation value, the value corresponding to the original mutation quantity information is controlled to be reduced by one.

[0151] When the value corresponding to the deviation length information is not greater than the reference deviation value, it indicates that the current degree of change is small and it can be determined that it is not an independent pit. Figure 4 At this time, the value corresponding to the mutation quantity information is subtracted by one, so that subsequent calculations can determine a more accurate number of pit overlaps.

[0152] Reference Figure 6 , the bioreactor system disinfection method also includes:

[0153] S500: Determine the leeward section of the two approved sections determined by the same vertex according to the detection direction.

[0154] The leeward section is a section on the leeward side of the pit. The steam flow direction can be determined according to the detection direction, so that the two approved sections can be distinguished from each other.

[0155] S501: Determine the lateral length in the detection direction according to the vertex and the boundary point on the leeward road section.

[0156] The horizontal length is the distance between the order and the boundary point in the direction of the pipeline length.

[0157] S502: Calculate the slope value based on the telescopic length information and the horizontal length of the vertex.

[0158] The slope value is the average slope value of the leeward surface formed between the vertex and the boundary point in the leeward section of the pit, which is determined by dividing the telescopic length of the vertex by the horizontal length.

[0159] S503: Determine the slope value with the largest value according to the sorting rule, and determine the slope value as the upper limit of the slope.

[0160] The larger the slope, the more difficult it is for steam to process the leeward side. At this time, the slope of the leeward side that is most difficult to process is determined according to the sorting rules, and it is defined as the upper limit of the slope for identification, which is convenient for subsequent analysis and processing.

[0161] S504: Determine adjustment duration information corresponding to the upper slope limit value according to a preset adjustment matching relationship.

[0162] The duration value corresponding to the adjustment duration information is the duration value that needs to be updated for the disinfection duration. Due to different slope conditions, the required adjustment duration is also different. The adjustment matching relationship between the two is determined in advance by the staff based on multiple tests, which will not be repeated here.

[0163] S505: Perform sum calculation based on the adjusted duration information and the original disinfection duration information to update the disinfection duration information.

[0164] The original disinfection time can be updated by adjusting the time, so that the determined disinfection time can be adaptively adjusted according to the difficulty of pit disinfection treatment, thereby achieving a better disinfection effect inside the pipeline.

[0165] Reference Figure 7 , the bioreactor system disinfection method also includes:

[0166] S600: Determine whether the quantity value corresponding to the pit quantity information is greater than a preset qualified upper limit value.

[0167] The qualified upper limit value is the maximum number of pits allowed to appear when the staff determines that the pipeline can be disinfected normally and efficiently. The purpose of the judgment is to know whether the current pipeline can be disinfected normally and efficiently.

[0168] S6001: If the quantity value corresponding to the pit quantity information is not greater than the qualified upper limit, a pipeline normal signal is output.

[0169] When the quantity value corresponding to the pit quantity information is not greater than the qualified upper limit value, it means that the pipeline is normal. At this time, a pipeline normal signal is output to identify the situation so that the staff can know the specific situation of the pipeline.

[0170] S6002: If the quantity value corresponding to the pit quantity information is greater than the qualified upper limit, a replacement prompt signal is output, and a difference calculation is performed based on the pit quantity information and the qualified upper limit to determine the excess quantity.

[0171] When the quantity value corresponding to the pit quantity information is greater than the qualified upper limit, it means that there is a certain problem with the pipeline. At this time, a replacement prompt signal is output to inform the staff that the pipeline needs to be replaced; the system pipeline is composed of multiple sections of pipelines, so further analysis is required for the pipeline that needs to be replaced; the excess quantity is the number of extra pits in the entire pipeline, which is determined by subtracting the qualified upper limit from the quantity value corresponding to the pit quantity information.

[0172] S601: Count the pits on each pipeline to determine the number of pits in a single pipeline.

[0173] The number of single-pipe pits is the total number of pits in each section of the pipeline, which can be obtained by counting the pits one by one.

[0174] S602: Sort all single-tube pit numbers from large to small according to the sorting rule, and sum up the single-tube pit numbers in order from large to small to determine the total number of multi-tube pits. When the total number of multi-tube pits is not less than the excess number, the pipeline corresponding to the summed single-tube pit number is defined as an abnormal pipeline to be replaced.

[0175] According to the sorting rules, the pipelines with the most pits can be sorted from the least. The total number of multi-pipe pits is the number of all pits on the determined multiple pipelines. For example, the order of the pipeline pits is 5, 4, 2, and 1, and the total number of multi-pipe pits is 5, 9, 11, and 12. When the total number of multi-pipe pits is not less than the excess number, it means that the determined pipeline already contains the excess number of pits. At this time, only these pipelines need to be replaced to make the entire system pipeline work normally. At this time, the pipeline is defined as an abnormal pipeline to be replaced for identification, so that subsequent staff can carry out targeted replacement.

[0176] Reference Figure 8 , the method of sorting the number of pits of all single tubes from large to small according to the sorting rules includes:

[0177] S700: Determine whether the number of pits in the single tubes is equal.

[0178] The purpose of the judgment is to find out whether there is a situation where the number of pits is the same and cannot be sorted.

[0179] S7001: If the number of pits in a single tube is unequal, sort them by size.

[0180] When the number of pits in a single pipe is not equal, it means that the number of pits in the two pipelines is inconsistent, and sorting operations can be performed based on the size.

[0181] S7002: If the number of single-pipe pits is equal, the pipelines with the same number of single-pipe pits are defined as similar pipelines, and the pipelines with a number of single-pipe pits greater than the current number of single-pipe pits are defined as disassembled pipelines.

[0182] When the number of pits in a single pipe is equal, it means that the number of pits in the two pipes is the same and they cannot be sorted by the number of pits. In this case, the pipe is defined as a similar pipe for identification, so that pipes with the same number of pits can be distinguished. At the same time, a disassembly pipe is defined to find the pipe that can be placed ahead of the pipe in the sorting, which is convenient for subsequent analysis.

[0183] S701: Pipelines adjacent to similar pipelines and being dismantling pipelines are defined as easily dismantled pipelines, and the easily dismantled pipelines are counted to determine the number of easily dismantled pipelines corresponding to each similar pipeline.

[0184] When similar pipelines need to be replaced, it means that the disassembled pipelines must be replaced. Easy-to-remove pipelines are defined to identify the pipeline distribution. The easy-to-remove quantity is the quantity value of the easy-to-remove pipelines corresponding to the similar pipelines.

[0185] S702: Sort similar pipelines according to the number of easily dismantled pipelines from large to small, and sort them according to the detection direction if the number of easily dismantled pipelines is the same.

[0186] The more easily disassembled ones there are, the more adjacent pipelines that need to be replaced. At this time, it is more convenient to replace the current similar pipelines. Therefore, by sorting according to the number of easily disassembled ones, the difficulty of replacing similar pipelines can be known, so that effective sorting can be performed. When the number of easily disassembled ones is the same, it means that the disassembly difficulty is consistent. At this time, they can be sorted in sequence according to their positions in the detection direction, so that effective sorting of all pipelines with pits can be achieved.

[0187] Reference Figure 9 Based on the same inventive concept, an embodiment of the present invention provides a bioreactor system disinfection system, comprising:

[0188] An acquisition module is used to obtain a disinfection operation signal;

[0189] A processing module, connected to the acquisition module and the judgment module, for storing and processing information;

[0190] The judgment module is connected with the acquisition module and the processing module and is used for judging the information;

[0191] When the disinfection operation signal is consistent with the preset disinfection processing signal, the processing module controls the detection device mounted on the outer surface of the pipeline to move along a preset detection direction, and causes the acquisition module to acquire telescopic length information of the telescopic component preset on the inner side wall of the detection device and abutting against the outer surface of the pipeline;

[0192] The judging module judges whether the length value corresponding to the telescopic length information is within a preset normal length range;

[0193] If the judging module determines that the length value corresponding to the telescopic length information is within the normal length range, the processing module defines the pipeline position as a normal point;

[0194] If the judging module determines that the length value corresponding to the telescopic length information is not within the normal length range, the processing module defines the pipeline position as an abnormal point;

[0195] The processing module forms a pipeline condition axis based on the combination of normal points and abnormal points, establishes a movable virtual moving point on the pipeline condition axis, and controls the virtual moving point to move along the detection direction;

[0196] The processing module outputs a pit start signal when the virtual moving point switches from a normal point to an abnormal point during the movement of the virtual moving point, and outputs a pit end signal when the abnormal point switches to a normal point;

[0197] The processing module determines the pit quantity information according to the pit start signal and the pit end signal after the virtual moving point finishes moving;

[0198] The processing module determines the disinfection duration information corresponding to the pit quantity information according to a preset duration matching relationship, and controls the disinfection equipment to perform the disinfection operation according to the disinfection duration information;

[0199] A pothole condition determination module is used to determine the abnormal condition of a pothole so that the determined pothole section is more accurate;

[0200] A pit overlap analysis module is used to analyze the situation of pit overlap so as to make the determined number of pits more accurate;

[0201] Abnormal mutation analysis module, used to analyze the pit situation to improve the accuracy of pit number determination;

[0202] The disinfection time update module determines the appropriate disinfection time according to the slope of the pit, so as to achieve the best disinfection effect;

[0203] Abnormal pipeline marking module, used to mark pipelines that need to be replaced, so that subsequent staff can replace them;

[0204] The abnormal pipeline sorting module is used to effectively sort the pipelines on the road sections with potholes, so as to facilitate the subsequent marking and processing of the pipelines.

[0205] Those skilled in the art will clearly understand that for the sake of convenience and brevity, the division of the above-mentioned functional modules is only used as an example for illustration. In actual applications, the above-mentioned functions can be assigned to different functional modules as needed, that is, the internal structure of the device can be divided into different functional modules to complete all or part of the functions described above. The specific working processes of the above-mentioned systems, devices, and units can refer to the corresponding processes in the aforementioned method embodiments and will not be repeated here.

[0206] An embodiment of the present invention provides a computer-readable storage medium storing a computer program capable of being loaded by a processor and executing a method for disinfecting a biological reaction system.

[0207] Computer storage media include, for example, various media that can store program codes, such as USB flash drives, mobile hard disks, read-only memories (ROMs), random access memories (RAMs), magnetic disks, or optical disks.

[0208] Based on the same inventive concept, an embodiment of the present invention provides an intelligent terminal including a memory and a processor, wherein the memory stores a computer program that can be loaded by the processor and execute a method for disinfecting a biological reaction system.

[0209] Those skilled in the art will clearly understand that for the sake of convenience and brevity, the division of the above-mentioned functional modules is only used as an example for illustration. In actual applications, the above-mentioned functions can be assigned to different functional modules as needed, that is, the internal structure of the device can be divided into different functional modules to complete all or part of the functions described above. The specific working processes of the above-mentioned systems, devices, and units can refer to the corresponding processes in the aforementioned method embodiments and will not be repeated here.

[0210] The above are all preferred embodiments of the present application and are not intended to limit the scope of protection of this application. Unless otherwise specified, any feature disclosed in this specification (including the abstract and drawings) may be replaced by other equivalent or similar features. In other words, unless otherwise specified, each feature is merely an example of a series of equivalent or similar features.

Claims

1. A method for disinfecting a biological reaction system, characterized in that: include: Obtain disinfection operation signal; When the disinfection operation signal is consistent with the preset disinfection processing signal, the detection device mounted on the outer surface of the pipeline is controlled to move along a preset detection direction, and information on the telescopic length of the telescopic component preset on the inner side wall of the detection device and abutting against the outer surface of the pipeline is obtained; Determine whether the length value corresponding to the telescopic length information is within a preset normal length range; If the length value corresponding to the telescopic length information is within the normal length range, the pipeline position is defined as a normal point; If the length value corresponding to the telescopic length information is not within the normal length range, the pipeline position is defined as an abnormal point; A pipeline condition axis is formed based on the combination of normal points and abnormal points, and a movable virtual moving point is established on the pipeline condition axis, and the virtual moving point is controlled to move along the detection direction; During the movement of the virtual moving point, when the virtual moving point switches from a normal point to an abnormal point, a pit start signal is output, and when the abnormal point switches to a normal point, a pit end signal is output; After the virtual moving point finishes moving, the pit quantity information is determined according to the pit start signal and the pit end signal; The disinfection time information corresponding to the pit quantity information is determined according to the preset time matching relationship, and the disinfection equipment is controlled to perform the disinfection operation according to the disinfection time information.

2. The bioreactor system disinfection method according to claim 1, characterized in that: After the virtual moving point is moved, the bioreactor system disinfection method further includes: The position of the virtual moving point when the pit start signal is output is defined as the start point, and the position of the virtual moving point when the pit end signal adjacent to the pit start signal in the detection direction is output is defined as the end point; Calculate the distance information based on the starting point and the corresponding ending point; Determine whether the distance value corresponding to the distance information is greater than a preset reference distance value; If the distance value corresponding to the distance information is greater than the reference distance value, the road section between the start point and the end point is defined as a pothole section, and the original state of each signal is maintained; If the distance value corresponding to the interval distance information is not greater than the reference distance value, the pit start signal outputted at the start point and the pit end signal outputted at the corresponding end point are cancelled.

3. The bioreactor system disinfection method according to claim 2, characterized in that: After the pothole section is identified, the bioreactor system disinfection method also includes: Determine, on the pothole section, the telescopic length information with the largest corresponding value among all telescopic length information according to a preset sorting rule, define the abnormal point corresponding to the telescopic length information as a vertex, and define the abnormal points at both ends of the pothole section as boundary points; The road section whose vertex points to the boundary point is defined as the approved road section, and the difference between the expansion and contraction length information corresponding to adjacent abnormal points on a single approved road section is calculated to determine the difference length information, where the difference length information is the expansion and contraction length information of the abnormal point close to the vertex minus the expansion and contraction length information of the abnormal point far from the vertex; Performing difference calculation based on adjacent difference length information to determine the change length information; When the length value corresponding to the change length information is greater than a preset allowable change value, a mutation signal is output, and a count is performed according to the mutation signal to determine the number of mutations; On the pothole section, calculation is performed based on the two mutation quantity information to determine the pothole overlap quantity; The pit quantity information is updated by performing a sum calculation based on the pit overlap quantity and the original pit quantity information.

4. The bioreactor system disinfection method according to claim 3, characterized in that: After the mutation signal is output, the bioreactor system disinfection method further includes: The corresponding abnormal point is defined as a mutation point, and the stretching length information corresponding to the mutation point is defined as the mutation length information; Perform difference calculation based on the mutation length information of adjacent mutation points to determine the deviation length information; Determine whether the value corresponding to the deviation length information is greater than a preset reference deviation value; If the value corresponding to the deviation length information is greater than the baseline deviation value, the original mutation quantity information is maintained; If the value corresponding to the deviation length information is not greater than the reference deviation value, the value corresponding to the original mutation quantity information is controlled to be reduced by one.

5. The bioreactor system disinfection method according to claim 3, characterized in that: Also includes: Determine the leeward section of the leeward side of the two approved sections determined by the same vertex according to the detection direction; On the leeward section, determine the lateral length in the detection direction based on the vertex and boundary points; The slope value is determined by calculating the extension length information of the vertex and the horizontal length; Determine the slope value with the largest value according to the sorting rule, and determine the slope value as the upper limit value of the slope; Determine the adjustment duration information corresponding to the upper limit of the slope according to the preset adjustment matching relationship; The disinfection time information is updated by summing the adjusted time information and the original disinfection time information.

6. The bioreactor system disinfection method according to claim 5, characterized in that: Also includes: Determining whether the quantity value corresponding to the pit quantity information is greater than a preset qualified upper limit; If the number value corresponding to the pit quantity information is not greater than the qualified upper limit, a pipeline normal signal is output; If the quantity value corresponding to the pit quantity information is greater than the qualified upper limit, a replacement prompt signal is output, and a difference calculation is performed based on the pit quantity information and the qualified upper limit to determine the excess quantity; The number of pits on each pipe is determined by counting the pits on each pipe; According to the sorting rules, all single-tube pit numbers are sorted from large to small, and the single-tube pit numbers are summed up in sequence from large to small to determine the total number of multi-tube pits. When the total number of multi-tube pits is not less than the excess number, the pipeline corresponding to the summed single-tube pit number is defined as the abnormal pipeline to be replaced.

7. The bioreactor system disinfection method according to claim 6, characterized in that: Methods for sorting the number of pits in all single tubes from large to small according to the sorting rules include: Determine whether the number of pits in a single tube is equal; If the number of pits in a single tube is unequal, they are sorted according to size; If the number of single-pipe pits is equal, the pipelines with the same number of single-pipe pits are defined as similar pipelines, and the pipeline with a single-pipe pit number greater than the current single-pipe pit number is defined as a disassembled pipeline; The pipelines adjacent to similar pipelines and being dismantled are defined as easily dismantled pipelines, and the easily dismantled pipelines are counted to determine the number of easily dismantled pipelines corresponding to each similar pipeline; Similar pipelines are sorted from largest to smallest according to the number of easily dismantled pipelines, and if the number of easily dismantled pipelines is the same, they are sorted according to the detection direction.

8. A bioreactor system disinfection system, characterized in that: include: An acquisition module is used to obtain a disinfection operation signal; A processing module, connected to the acquisition module and the judgment module, for storing and processing information; The judgment module is connected with the acquisition module and the processing module and is used for judging the information; When the disinfection operation signal is consistent with the preset disinfection processing signal, the processing module controls the detection device mounted on the outer surface of the pipeline to move along a preset detection direction, and causes the acquisition module to acquire telescopic length information of the telescopic component preset on the inner side wall of the detection device and abutting against the outer surface of the pipeline; The judging module judges whether the length value corresponding to the telescopic length information is within a preset normal length range; If the judging module determines that the length value corresponding to the telescopic length information is within the normal length range, the processing module defines the pipeline position as a normal point; If the judging module determines that the length value corresponding to the telescopic length information is not within the normal length range, the processing module defines the pipeline position as an abnormal point; The processing module forms a pipeline condition axis based on the combination of normal points and abnormal points, establishes a movable virtual moving point on the pipeline condition axis, and controls the virtual moving point to move along the detection direction; The processing module outputs a pit start signal when the virtual moving point switches from a normal point to an abnormal point during the movement of the virtual moving point, and outputs a pit end signal when the abnormal point switches to a normal point; The processing module determines the pit quantity information according to the pit start signal and the pit end signal after the virtual moving point finishes moving; The processing module determines the disinfection time information corresponding to the pit quantity information according to a preset time matching relationship, and controls the disinfection equipment to perform the disinfection operation according to the disinfection time information.

9. An intelligent terminal, characterized in that: The method comprises a memory and a processor, wherein the memory stores a computer program that can be loaded by the processor and executes the method according to any one of claims 1 to 7.

10. A computer-readable storage medium, characterized in that A computer program is stored which can be loaded by a processor and execute the method according to any one of claims 1 to 7.

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