Reagent bottle clamp and sample addition system

Abstract

The application discloses a reagent bottle clamp and a sample adding system. The reagent bottle clamp comprises a clamp body, a clamping arm and a limiting piece. The clamp body is provided with a receiving cavity and a first opening communicating with the receiving cavity and used for the reagent bottle to enter or exit the receiving cavity. The clamping arm comprises a hinged end, a free end and a squeezing part. The clamping arm is rotationally connected to the clamp body through the hinged end. The squeezing part squeezes or releases the reagent bottle in the receiving cavity when the clamping arm rotates relative to the clamp body. The limiting piece is connected to the clamp body and is used to limit the rotation angle stroke of the clamping arm relative to the clamp body, so as to limit the squeezing degree of the squeezing part to the reagent bottle. According to the application, the limiting piece is arranged to limit the rotation angle stroke of the clamping arm relative to the clamp body. Therefore, the squeezing degree of the reagent bottle is fixed and controllable when the squeezing part of the clamping arm squeezes the reagent bottle each time. In turn, the application is helpful to realize the quantitative sample adding of the substance in the reagent bottle.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of blood sample detection, and particularly relates to a reagent bottle clamp and a sample adding system. BACKGROUND

[0002] In a blood sample detection process, a blood sample collected and an auxiliary medicament such as a buffer need to be fully mixed in a reagent bottle, and then the mixed blood sample is added to a detection card for further blood sample detection. In the prior art, a user directly squeezes the reagent bottle to add the blood sample, and it is difficult to achieve quantitative sample adding. SUMMARY

[0003] The application aims to provide a reagent bottle clamp and a sample adding system to achieve quantitative sample adding of a reagent bottle.

[0004] To solve the above technical problem, the application is implemented as follows:

[0005] In a first aspect, the application provides a reagent bottle clamp, comprising:

[0006] a clamp body, the clamp body having a receiving cavity and a first opening in communication with the receiving cavity and used for reagent bottles to enter or exit the receiving cavity;

[0007] a clamping arm, the clamping arm comprising a hinged end, a free end and a squeezing portion, the clamping arm being rotationally connected to the clamp body through the hinged end, and the squeezing portion squeezing or releasing the reagent bottle in the receiving cavity when the clamping arm rotates relative to the clamp body;

[0008] a limiting piece, the limiting piece being connected to the clamp body and used to limit the rotation angle stroke of the clamping arm relative to the clamp body, so as to limit the squeezing degree of the squeezing portion on the reagent bottle.

[0009] In a second aspect, the application further provides a sample adding system, comprising:

[0010] a reagent bottle, the reagent bottle comprising a mixing cavity and a second opening in communication with the mixing cavity;

[0011] a catheter, the catheter comprising a blood sampling end and a sample adding end in communication with each other, the blood sampling end being embedded into the mixing cavity from the second opening; and

[0012] The reagent bottle clamp is used to squeeze the reagent bottle, so that the sample in the reagent bottle is squeezed out from the sample adding end.

[0013] The reagent bottle clamp provided by the embodiment of the present application comprises a clamp body, a clamping arm and a limiting piece. The clamp body has a receiving cavity and a first opening in communication with the receiving cavity for the reagent bottle to enter or exit the receiving cavity. The clamping arm comprises a hinged end, a free end and a squeezing part. The clamping arm is rotationally connected to the clamp body through the hinged end. The squeezing part squeezes or releases the reagent bottle in the receiving cavity when the clamping arm rotates relative to the clamp body. The limiting piece is connected to the clamp body. The limiting piece is used to limit the rotation angle stroke of the clamping arm relative to the clamp body, so as to limit the squeezing degree of the squeezing part to the reagent bottle. The embodiment of the present application limits the rotation angle stroke of the clamping arm relative to the clamp body by setting the limiting piece. The squeezing degree of the reagent bottle is fixed and controllable when the squeezing part of the clamping arm squeezes the reagent bottle each time. Therefore, the quantitative sample adding of the substance in the reagent bottle is facilitated.

[0014] Additional aspects and advantages of the present application will be made apparent by the following description and the accompanying drawings. BRIEF DESCRIPTION OF DRAWINGS

[0015] The above and / or additional aspects and advantages of the present application will become apparent and be readily understood by considering the following detailed description, including the accompanying drawings, in which:

[0016] Figure 1 is a perspective structural schematic view of the reagent bottle clamp provided by the embodiment of the present application;

[0017] Figure 2 is one of the cross-sectional schematic views of the reagent bottle clamp and the reagent bottle when the limiting piece is rotationally connected to the clamp body;

[0018] Figure 3 is the second of the cross-sectional schematic views of the reagent bottle clamp and the reagent bottle when the limiting piece is rotationally connected to the clamp body;

[0019] Figure 4 is the third of the cross-sectional schematic views of the reagent bottle clamp and the reagent bottle when the limiting piece is rotationally connected to the clamp body;

[0020] Figure 5 is one of the cross-sectional schematic views of the reagent bottle clamp and the reagent bottle when the limiting piece is rotationally connected to the clamp body through a linear motion mechanism;

[0021] Figure 6 is the second of the cross-sectional schematic views of the reagent bottle clamp and the reagent bottle when the limiting piece is rotationally connected to the clamp body through a linear motion mechanism;

[0022] Figure 7 is the third of the cross-sectional schematic views of the reagent bottle clamp and the reagent bottle when the limiting piece is rotationally connected to the clamp body through a linear motion mechanism;

[0023] Figure 8is a linear motion mechanism, the limiting piece and the clip body assembly structure diagram;

[0024] Figure 9 is a spring, the reagent bottle clamp and the reagent bottle cross-section diagram;

[0025] Figure 10 is the reagent bottle, the conduit and the end cap explosion structure diagram.

[0026] The drawings: 100-reagent bottle clamp, 110-clip body, 111-receiving cavity, 112-first opening, 120-clamping arm, 121-hinged end, 122-free end, 123-pressing part, 130-limiting piece, 131-linear motion mechanism, 132-screw rod, 133-nut, 134-bearing, 140-torsion spring, 210-reagent bottle, 211-mixing cavity, 212-second opening, 220-conduit, 221-blood sampling end, 222-sample adding end, 230-end cap, 240-connection plate. DETAILED DESCRIPTION

[0027] The embodiments of the present application will be described in detail below, examples of which are shown in the drawings, wherein the same or similar notations represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary only, and are used only for explaining the present application, and cannot be understood as a limitation of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0028] The terms "first", "second" in the description and claims of the present application can explicitly or implicitly include one or more of the features. In the description of the present application, unless otherwise specified, the meaning of "a plurality of" is two or more. In addition, "and / or" in the specification and claims means at least one of the connected objects, and the character " / ", generally means that the front and rear associated objects are in an "or" relationship.

[0029] In the description of the present application, it is understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation of the present application.

[0030] In the description of the present application, it should be noted that unless specifically defined and limited otherwise, the terms "mounting", "connected", "connection" should be understood broadly, for example, can be fixed connection, can also be detachable connection, or integrally connected; can be mechanical connection, can also be electrical connection; can be directly connected, can also be indirectly connected through an intermediate medium, can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0031] As shown in Figures 1 to 7 The reagent bottle clamp 100 according to some embodiments of the present application includes:

[0032] The clamp body 110 has a receiving cavity 111 therein, and a first opening 112 in communication with the receiving cavity 111 for the reagent bottle 210 to enter or exit the receiving cavity 111;

[0033] The clamping arm 120 includes a hinged end 121, a free end 122, and a squeezing portion 123, the clamping arm 120 is rotatably connected to the clamp body 110 through the hinged end 121, and the squeezing portion 123 squeezes or releases the reagent bottle 210 in the receiving cavity 111 when the clamping arm 120 rotates relative to the clamp body 110;

[0034] The limiting member 130 is connected to the clamp body 110, and is used to limit the rotation angle stroke of the clamping arm 120 relative to the clamp body 110, so as to limit the squeezing degree of the squeezing portion 123 to the reagent bottle 210.

[0035] The reagent bottle clamp 100 provided by the embodiments of the present application can be used to clamp and squeeze the reagent bottle 210, so as to squeeze out the substance in the reagent bottle 210. In some possible implementation manners, the substance in the reagent bottle 210 can be a blood sample, or a liquid after the blood sample is fully mixed with an auxiliary reagent, wherein the auxiliary reagent can be a buffer, an anticoagulant, or a fluorescent agent, etc.; and in other possible implementation manners, the substance in the reagent bottle 210 can also be other types of samples or pure reagents, etc., which are not exemplified here. For the sake of simplicity of description, in the following embodiments, the substance in the reagent bottle 210 will mainly be taken as a blood sample mixed with an auxiliary reagent (which can be directly referred to as a blood sample hereinafter) as an example for description.

[0036] The clamp body 110 can be a structure with certain strength, and has the receiving cavity 111 therein, the receiving cavity 111 is in communication with the outside space through the first opening 112, so that the reagent bottle 210 can be inserted into the receiving cavity 111 from the first opening 112.

[0037] The clip body 110 is rotationally connected with a clamping arm 120. Specifically, the clamping arm 120 includes a hinged end 121, a free end 122, and a pressing portion 123. The hinged end 121 is connected with the clip body 110, so that the clamping arm 120 can rotate as a whole relative to the clip body 110. The free end 122 can be an operable end. For example, a user can contact the free end 122 and apply a force to the free end 122, thereby driving the clamping arm 120 to rotate about the hinged end 121.

[0038] In some examples, the pressing portion 123 can be a protruding structure. During rotation of the clamping arm 120, the pressing portion 123 can enter or exit the accommodating cavity 111. When the pressing portion 123 exits the accommodating cavity 111, it can be separated from the reagent bottle 210 located in the accommodating cavity 111. When the pressing portion 123 enters the accommodating cavity 111, it can contact and press the reagent bottle 210 located in the accommodating cavity 111. The reagent bottle 210 deforms, the internal volume decreases, and the internal blood sample is squeezed out.

[0039] Generally, the clamping arm 120 can be provided in pairs. For example, the number of clamping arms 120 is two. A user can simultaneously apply a force to the free ends 122 of the two clamping arms 120, so that the two pressing portions 123 simultaneously squeeze the reagent bottle 210. Of course, in some possible embodiments, the clamping arm 120 can be provided on one side of the clip body 110. The opposite side of the clip body 110 on which the clamping arm 120 is located can be provided with a fixed arm. The fixed arm is fixedly arranged on the clip body 110. A user can simultaneously apply a force to the clamping arm 120 and the fixed arm, so that the clamping arm 120 rotates about the clip body 110, and the pressing portion 123 squeezes the reagent bottle 210.

[0040] The clip body 110 is provided with a limiting piece 130. The limiting piece 130 can be used to limit the rotation angle stroke of the clamping arm 120 relative to the clip body 110. It is easy to understand that, during the process in which the pressing portion 123 contacts and squeezes the reagent bottle 210, as the clamping arm 120 rotates, the pressing portion 123 can be in a state of gradually deepening the degree of squeezing the reagent bottle 210. That is, the rotation angle of the clamping arm 120 is related to the degree of squeezing the reagent bottle 210 by the pressing portion 123. In this embodiment, the rotation angle stroke of the clamping arm 120 is limited by the limiting piece 130, so that the degree of squeezing the reagent bottle 210 by the pressing portion 123 can be limited.

[0041] With some examples, the limiting piece 130 can be fixed on the clip main body 110, the clamping arm 120 rotates under the driving of the user, the extrusion part 123 first contacts and then extrudes the reagent bottle 210, the blood sample is extruded from the reagent bottle 210, and when the clamping arm 120 rotates to a certain angle and contacts the limiting piece 130, at this time, the limiting piece 130 can limit the further movement of the clamping arm 120, and the clamping arm 120 reaches the maximum rotation angle stroke, and the extrusion degree of the extrusion part 123 on the reagent bottle 210 also reaches the maximum. It can be seen that due to the existence of the limiting piece 130, the user can consider that the extrusion degree of the extrusion part 123 on the reagent bottle 210 is fixed from the beginning of applying force to the clamping arm 120 to the clamping arm 120 reaching the maximum rotation angle stroke when the clamping arm 120 rotates, and the blood sample extruded from the reagent bottle 210 can also be considered to be quantitative.

[0042] Of course, in some other feasible embodiments, the position of the limiting piece 130 can be adjusted, and when the limiting piece 130 is in different positions, the clamping arm 120 can contact the limiting piece 130 at different rotation angles and be limited by the limiting piece 130 to further rotation movement, and specific structure implementation will be described in detail below.

[0043] The reagent bottle clip 100 provided by the embodiment of the application includes a clip main body 110, a clamping arm 120, and a limiting piece 130, the clip main body 110 has a containing cavity 111 and a first opening 112 communicating with the containing cavity 111 for the reagent bottle 210 to enter and exit the containing cavity 111, the clamping arm 120 includes a hinged end 121, a free end 122, and an extrusion part 123, the clamping arm 120 is rotationally connected to the clip main body 110 through the hinged end 121, and the extrusion part 123 extrudes or releases the reagent bottle 210 in the containing cavity 111 when the clamping arm 120 rotates relative to the clip main body 110, the limiting piece 130 is connected to the clip main body 110, and the limiting piece 130 is used to limit the rotation angle stroke of the clamping arm 120 relative to the clip main body 110 to limit the extrusion degree of the extrusion part 123 on the reagent bottle 210. The embodiment of the application limits the rotation angle stroke of the clamping arm 120 relative to the clip main body 110 by setting the limiting piece 130, so that the extrusion degree of the reagent bottle 210 is fixed and controllable when the reagent bottle 210 is extruded by the extrusion part 123 of the clamping arm 120 each time, thereby helping to realize the quantitative sampling of the substance in the reagent bottle 210.

[0044] The number of accommodation cavities 111 in the clip body 110 is one or more. In some possible embodiments, the number of accommodation cavities 111 can be set to be multiple, and one reagent bottle 210 can be placed in each accommodation cavity 111, that is, the accommodation cavities 111 and the reagent bottles 210 can have a corresponding relationship in quantity. Among them, the multiple accommodation cavities 111 can be independent of each other or can be in a mutually connected relationship, which can ensure that each accommodation cavity 111 can independently accommodate the reagent bottle 210.

[0045] In combination with some application scenarios, in order to improve the analysis efficiency of blood samples, the user can need to simultaneously operate multiple reagent bottles 210, and if multiple accommodation cavities 111 are arranged in a single clip body 110, the corresponding number of reagent bottles 210 can be accommodated, and the user can realize quantitative sampling from multiple reagent bottles 210 by operating the clamping arm 120 once.

[0046] In combination with some application scenarios, in order to improve the analysis efficiency of blood samples, the user can need to simultaneously operate multiple reagent bottles 210, and if multiple accommodation cavities 111 are arranged in a single clip body 110, the corresponding number of reagent bottles 210 can be accommodated, and the user can realize quantitative sampling from multiple reagent bottles 210 by operating the clamping arm 120 once. Figure 2 、 Figure 5 and Figure 9 The shape of the reagent bottle 210 can be different, so that the clip body 110 can adapt to reagent bottles 210 of different shapes, and the application range of the reagent bottle clip 100 can be improved.

[0047] In some possible embodiments, the different shapes of the accommodation cavities 111 can also realize the fool-proof design of the reagent bottles 210 of different shapes, so as to avoid affecting the quantitative sampling effect due to the incorrect or reverse clamping of the reagent bottle clip 100 on the reagent bottle 210.

[0048] In order to enable the squeezing part 123 to effectively squeeze the reagent bottle 210 in each accommodation cavity 111 when the user operates the clamping arm 120, in some embodiments, the number of the squeezing part 123 can be multiple, and the multiple squeezing parts 123 correspond to the multiple accommodation cavities 111 one by one, so that the reagent bottle 210 in each accommodation cavity 111 can be reliably squeezed by the corresponding squeezing part 123.

[0049] In some possible embodiments, the shapes of at least two squeezing parts 123 are different. For example, in combination with the case that the squeezing part 123 is a protruding structure on the clamping arm 120, the shapes of the squeezing parts 123 can be different in the degree of protrusion or the curvature of the protruding surface, and the like.

[0050] In some application scenarios, the shapes of the accommodation cavities 111 can be the same, and the shapes of the reagent bottles 210 that can be accommodated are also fixed. At this time, if the clamping arms 120 move by a certain angle until they contact the limit members 130, the extrusion degrees of the extrusion portions 123 of different shapes on the corresponding reagent bottles 210 can be different, and thus the amounts of blood samples taken out by different reagent bottles 210 are also different. It can be seen that by setting extrusion portions 123 of different shapes, the sampling requirements of different amounts of blood samples can be met.

[0051] In other application scenarios, the shapes of at least two accommodation cavities 111 can be different to accommodate reagent bottles 210 of different shapes. If the shapes of the extrusion portions 123 are kept the same, it can cause the amounts of blood samples taken out by different reagent bottles 210 to be different when the clamping arms 120 move by a certain angle. However, by reasonably setting the shapes of the extrusion portions 123, the shapes of the extrusion portions 123 can be different, and the amounts of blood samples taken out by reagent bottles 210 of different shapes can also be the same when the clamping arms 120 move by a certain angle.

[0052] As shown above, the number of clamping arms 120 can be one or more, such as Figures 1 to 7 As shown, in some preferred embodiments, the number of clamping arms 120 can be two. The two clamping arms 120 are arranged correspondingly. When a user operates the reagent bottle clamp 100, the user can simultaneously apply pressure to the free ends 122 of the two clamping arms 120. The two clamping arms 120 can symmetrically extrude the two sides of the reagent bottle 210, effectively avoiding the reagent bottle 210 from tilting during the operation, and thus ensuring the stability of the sampling process.

[0053] In some embodiments, each clamping arm 120 is connected to the clamp body 110 through an elastic member (not shown in the figure). In the case that the elastic member is in a released state, the extrusion portion 123 releases the reagent bottle 210 located in the accommodation cavity 111.

[0054] In combination with some examples, the elastic member can be a torsion spring or an elastic sheet, etc. The elastic member can have a released state, i.e., the state of the elastic member when a user does not apply force to the reagent bottle clamp 100. Corresponding to the released state, when a user applies force to the clamping arm 120, the elastic member will be deformed and be in a deformed state.

[0055] When the elastic element is in the released state, the squeezing part 123 can release the reagent bottle 210 located in the accommodating cavity 111. In some examples, the clamp body 110 is provided with an opening communicating with the accommodating cavity 111. When the user applies force to the clamping arm 120, the squeezing part 123 can move from the opening into the accommodating cavity 111 to squeeze the reagent bottle 210. When the user releases the clamping arm 120, under the action of the elastic element's rebound force, the squeezing part 123 can leave the accommodating cavity 111, thereby releasing the reagent bottle 210 located in the accommodating cavity 111.

[0056] In some implementations, such as Figure 9 As shown, both clamping arms 120 have a torsion spring 140 at their hinge ends 121. The first end of the torsion spring 140 is connected to the clamp body 110, and the second end of the torsion spring 140 is connected to the hinge end 121 of the clamping arm 120.

[0057] Of course, in some feasible implementations, even if the elastic element is in the released state, the squeezing part 123 can be located in the accommodating cavity 111, for example, it can be in slight contact with the reagent bottle 210, and can fix the reagent bottle 210 by static friction, while not causing the blood sample to drip due to excessive squeezing of the reagent bottle 210.

[0058] In some implementations, such as Figures 2 to 7 As shown, the distance between the hinge end 121 and the free end 122 of the clamping arm 120 is greater than the distance between the hinge end 121 and the pressing part 123.

[0059] It is easy to understand that the clamping arm 120 can be considered as a lever with the hinge end 121 as the center of rotation. The free end 122 can receive the user's driving force, while the squeezing part 123 is subject to the resistance provided by the reagent bottle 210. The distance between the hinge end 121 and the free end 122 is greater than the distance between the hinge end 121 and the squeezing part 123. In normal scenarios, this makes the lever arm corresponding to the driving force greater than the lever arm corresponding to the resistance. Thus, the user can use a smaller force to drive the reagent bottle clamp 100 to squeeze the reagent bottle 210 to complete the blood sample collection, achieving a labor-saving effect.

[0060] In some preferred embodiments, the free end 122 and the compression part 123 are located on the same side of the hinge end 121, which makes the overall arrangement of the reagent bottle clamp 100 more compact and reduces the overall size of the reagent bottle clamp 100.

[0061] As shown above, the limiting member 130 can be fixed on the clip body 110 or movably connected to the clip body 110. When the limiting member 130 is fixedly connected to the clip body 110, different quantitative requirements can be achieved by replacing the limiting member 130 with different widths. When the limiting member 130 is movably connected to the clip body 110, the rotation angle stroke of the limiting member 130 relative to the clip body 110 is changed, so that the use amount of the blood sample can be adjusted, and the function of the reagent bottle clip 100 is enriched.

[0062] The following is an example of the structure of the limiting member 130 movably connected to the clip body 110.

[0063] Alternatively, as shown in Figures 2 to 4 , the limiting member 130 is rotatably connected to the clip body 110, and the limiting member 130 has a surface with a variable outer diameter, so as to adjust the distance between the limiting member 130 and the clamping arm 120 in the thickness direction of the clamping arm 120 when the limiting member 130 is rotated.

[0064] In some examples, the shape of the limiting member 130 can be an oval or an approximately oval shape, so that the limiting member 130 has a surface with a variable outer diameter. In combination with Figures 2 to 4 , the limiting member 130 is defined to be located in the middle of the left and right clamping arms 120, and when the limiting member 130 is rotated, the length in the left-right direction changes due to the change in the outer diameter. When the length of the limiting member 130 in the left-right direction is large, the gap between the limiting member 130 and the clamping arm 120 is short, and the clamping arm 120 can be touched by the limiting member 130 by rotating a small angle; on the contrary, when the length of the limiting member 130 in the left-right direction is small, the gap between the limiting member 130 and the clamping arm 120 is long, and the clamping arm 120 can be touched by the limiting member 130 by rotating a large angle. That is, by rotating the limiting member 130, the rotation angle stroke of the clamping arm 120 can be adjusted, and then the degree of extrusion of the extrusion part 123 to the reagent bottle 210 is adjusted, so as to achieve the effect of adjusting the use amount of the blood sample.

[0065] Of course, in actual application, the surface of the limiting member 130 can also be discontinuous, for example, there can be multiple pairs of arc surfaces, and the distances from different groups of arc surfaces to the rotation center of the limiting member 130 are different, so that the length in the left-right direction changes when the limiting member 130 is rotated, and then the rotation angle stroke of the clamping arm 120 is adjusted.

[0066] In some possible embodiments, the limiting member 130 and the clip body 110 can be connected through a rotating pair with a high friction coefficient, so that the limiting member 130 has a certain fixing strength with the clip body 110 at each angle position, avoiding that the user operates the clamping arm 120 to drive the limiting member 130 to rotate. In other possible embodiments, the limiting member 130 and the clip body 110 can also be connected through a ratchet or the like.

[0067] Optionally, as shown in Figures 5 to 7 the limiting member 130 is movably connected with the clip body 110 through a linear motion mechanism 131, and the linear motion mechanism 131 is used to adjust the position of the limiting member 130 in the length extension direction of the clamping arm 120.

[0068] In some examples, the linear motion mechanism 131 can be a lead screw mechanism, or a positioning hole and a positioning rod that can be adjusted in the length direction, and the contact surfaces of the two can have a certain elasticity or have a high friction coefficient, so that the positioning rod can be fixed at multiple depth positions of the positioning hole, thereby adjusting the linear distance between the limiting member 130 and the clip body 110. Of course, in some possible embodiments, the limiting member 130 can also be simply connected with the clip body 110 through a screw, and when the limiting member 130 is rotated, the limiting member 130 will produce a linear displacement relative to the clip body 110.

[0069] In combination with the example of Figures 5 to 7 the limiting member 130 can be located in the middle of the left and right clamping arms 120, and the clamping arm 120 rotates a certain angle around the hinged end 121, and the linear displacement of the position of the clamping arm 120 away from the hinged end 121 is greater. Assuming that in a certain state, the extension direction of the clamping arm 120 from the hinged end 121 to the free end 122 is consistent with the linear motion direction of the limiting member 130, at this time, the distance between the limiting member 130 and the clamping arm 120 is equal when the limiting member 130 moves to any position. However, when the clamping arm 120 is rotated, in the case of rotating the same angle, the position close to the free end 122 moves a distance greater than the position close to the hinged end 121. Correspondingly, the closer the limiting member 130 moves to the free end 122, the more the clamping arm 120 touches the limiting member 130 at a smaller rotation angle stroke; the closer the limiting member 130 moves to the hinged end 121, the more the clamping arm 120 touches the limiting member 130 at a larger rotation angle stroke. It can be seen that adjusting the position of the limiting member 130 based on the linear motion mechanism 131 can realize the adjustment of the rotation angle stroke of the clamping arm 120, and further realize the adjustment of the extrusion degree of the extrusion part 123 to the reagent bottle 210, so as to achieve the effect of adjusting the taking amount of the blood sample.

[0070] Of course, the above is a principle of the adjustment of the blood sample taking amount of the reagent bottle clamp 100 based on the linear motion mechanism 131. In actual applications, the shape of the clamping arm 120 and the relative positional relationship between the clamping arm 120 and the limiting piece 130 can be adjusted as needed, and will not be illustrated one by one here.

[0071] As shown above, in some embodiments, a plurality of accommodation cavities 111 can be arranged in the clamp body 110, and the accommodation cavities 111 are sequentially arranged in the width direction of the clamp body 110. Such a structure makes the clamp body 110 and the clamping arm 120 have a larger width. As some feasible embodiments, the limiting piece 130 can be designed as an elongated structure to reliably contact the clamping arm 120, thereby reliably limiting the rotation angle stroke of the clamping arm 120.

[0072] However, the clamping arm 120 is arranged on the left and right sides of the limiting piece 130, which may Figure 8 As shown above, in some embodiments, the linear motion mechanism 131 is a lead screw mechanism, which includes a lead screw 132 and a nut 133. The lead screw 132 is fixedly connected with the clamp body 110, and the nut 133 is rotationally connected with the limiting piece 130 and axially fixed relative to the limiting piece 130.

[0073] The nut 133 is rotationally connected with the limiting piece 130 and axially fixed relative to the limiting piece 130. The nut 133 and the limiting piece 130 can be connected through a bearing 134. In a specific example, the nut 133 can have an upper manual adjusting part and a lower rotation connecting part. The outer surface of the rotation connecting part is connected with the limiting piece 130 through the bearing 134. When adjusting the position of the limiting piece 130, the user can rotate the nut 133. The rotation of the nut 133 relative to the lead screw 132 is converted into linear motion along the circumference of the lead screw. Since the nut 133 is axially fixed relative to the limiting piece 130, the limiting piece 130 can be driven to produce linear motion. At the same time, since the nut 133 is rotationally connected with the limiting piece 130, the rotation of the nut 133 does not cause the rotation of the limiting piece 130, thereby adapting to the scene where the clamping arm 120 forms a rotation limitation for the limiting piece 130. Of course, in actual applications, the nut 133 and the limiting piece 130 can also be rotationally connected and axially fixed relative to each other through other connection forms, which will not be illustrated one by one here.

[0074] In some possible embodiments, an external gear (not shown in the figure) can be further arranged on the nut 133, and an indicating disc (not shown in the figure) can be rotatably arranged on the limiting member 130, the indicating disc and the external gear are intermeshed, by reasonably adjusting the transmission ratio of the two, the indicating disc can indicate the position of the nut 133, and the position of the nut 133 will affect the position of the limiting member 130 and the rotation angle stroke of the clamping arm 120, and then affect the sampling amount of the blood sample of the reagent bottle clamp 100. Through calibration test or theoretical calculation, the indicating value corresponding to the indicating disc can be set as the sampling amount of the blood sample, in this way, the user can determine the adjustment amount of the nut 133 by observing the indication of the indicating disc, and then realize the accurate adjustment of the sampling amount of each blood sample.

[0075] The embodiments of the present application also provide a sample adding system, which comprises the reagent bottle 210 and the reagent bottle clamp 100.

[0076] In some embodiments, as shown in Figures 1 to 10 The sample adding system can specifically comprise:

[0077] The reagent bottle 210 comprises a mixing cavity 211 and a second opening 212 in communication with the mixing cavity 211;

[0078] The catheter 220 comprises a blood sampling end 221 and a sample adding end 222 in communication with each other, the blood sampling end 221 is embedded into the mixing cavity 211 from the second opening 212;

[0079] and the reagent bottle clamp 100 described above, the reagent bottle clamp 100 is used for squeezing the reagent bottle 210, so that the sample in the reagent bottle 210 is squeezed out from the sample adding end 222.

[0080] As shown in Figure 10 The reagent bottle 210 and the catheter 220 can be matched, the blood sampling end 221 of the catheter 220 can adopt a capillary structure to collect the blood sample by capillary action. After the catheter 220 completes the collection of the blood sample, the sample adding end 222 can be inserted into the mixing cavity 211 from the second opening 212, the reagent bottle 210 and the catheter 220 can be combined with each other, at this time the mixing cavity 211 is in communication with the outside through the blood sampling end 221.

[0081] The mixing cavity 211 can be pre-injected with auxiliary medicaments such as buffer agents, and after the catheter 220 is inserted into the reagent bottle 210, the blood sample can be mixed with the buffer agent in the mixing cavity 211, and the mixed blood sample (which can be referred to as a blood sample for short) is in a state ready for sampling. At this time, the reagent bottle 210 can be inserted into the accommodation cavity 111 from the first opening 112 of the reagent bottle clamp 100, and the user can drive the clamping arm 120 to squeeze the blood sample in the reagent bottle 210 from the sampling end 222. Since the reagent bottle clamp 100 has a limiting piece 130, the rotation angle of the clamping arm 120 can be limited, thereby realizing quantitative sampling of the blood sample.

[0082] Of course, in actual application, the sample in the reagent bottle 210 can be a blood sample, or other types of samples such as water samples or urine samples.

[0083] As shown in FIG. 1, Figure 10 In some embodiments, the blood sample to be sampled can need to be stored or transported, etc. To avoid the blood sample from being mistakenly poured out or contaminated during this period, the above-mentioned catheter 220 can be provided with an end cap 230, and the end cap 230 can be detachably connected to the blood sampling end 221 of the catheter 220. In this way, the two ends of the catheter 220 are sealed by the reagent bottle 210 and the end cap 230, respectively, thereby isolating the blood sample from the external environment; when sampling is needed, the end cap 230 can be detached from the catheter 220.

[0084] In the above embodiment, it is mentioned that the number of accommodation cavities 111 in the clamp body 110 can be multiple, and accordingly, the number of reagent bottles 210 and catheters 220 can also be multiple, and there is a corresponding relationship in the number, and the multiple catheters 220 can be fixed by the connecting plate 240.

[0085] It is easy to understand that the sampling system is a system including the reagent bottle clamp 100 in the above embodiment, and the embodiments of the reagent bottle clamp 100 can also be used in the embodiments of the sampling system and achieve corresponding technical effects, which will not be repeated here.

[0086] In the description of this specification, the description of the terms "one embodiment", "some embodiments", "illustrative embodiment", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0087] While the embodiments of the application have been shown and described, it is to be understood that the embodiments can be varied, modified, substituted and changed by those skilled in the art without departing from the principles and spirit of the application, the scope of which is defined by the claims and their equivalents.

Claims

1. A reagent bottle clamp, characterized in that, include: The clamp body (110) has a receiving cavity (111) and a first opening (112) communicating with the receiving cavity (111) for the reagent bottle (210) to enter and exit the receiving cavity (111); A clamping arm (120) includes a hinged end (121), a free end (122), and a squeezing part (123). The clamping arm (120) is rotatably connected to the clamp body (110) through the hinged end (121). The squeezing part (123) squeezes or releases the reagent bottle (210) located in the accommodating cavity (111) as the clamping arm (120) rotates relative to the clamp body (110). A limiting member (130) is connected to the clamp body (110). The limiting member (130) is used to limit the rotational angular travel of the clamping arm (120) relative to the clamp body (110) so as to limit the degree of compression of the squeeze part (123) on the reagent bottle (210). The limiting member (130) is movably connected to the clamp body (110), and the limiting member (130) moves relative to the clamp body (110) to change the rotation angle stroke; there are two clamping arms (120), and the two clamping arms (120) are arranged symmetrically.

2. The reagent bottle clamp according to claim 1, characterized in that, The limiting member (130) is movably connected to the clamp body (110) via a linear motion mechanism (131), which is used to adjust the position of the limiting member (130) in the length extension direction of the clamping arm (120).

3. The reagent bottle clamp according to claim 2, characterized in that, The linear motion mechanism (131) is a lead screw mechanism, which includes a lead screw (132) and a nut (133). The lead screw (132) is fixedly connected to the clamp body (110), and the nut (133) is rotatably connected to the limiting member (130) and fixed relative to it in the axial direction.

4. The reagent bottle clamp according to claim 1, characterized in that, The limiting member (130) is rotatably connected to the clamp body (110). The limiting member (130) has a surface with varying outer diameter to adjust the distance between the limiting member (130) and the clamping arm (120) in the thickness direction of the clamping arm (120) when the limiting member (130) rotates.

5. The reagent bottle clamp according to claim 1, characterized in that, The distance between the hinge end (121) and the free end (122) is greater than the distance between the hinge end (121) and the pressing part (123).

6. The reagent bottle clamp according to claim 1, characterized in that, The number of the receiving cavities (111) is multiple, and at least two of the receiving cavities (111) have different shapes to adapt to reagent bottles (210) of different shapes.

7. The reagent bottle clamp according to claim 6, characterized in that, There are multiple extrusion sections (123), and each extrusion section (123) corresponds to one of the multiple accommodating cavities (111). At least two extrusion sections (123) have different shapes.

8. The reagent bottle clamp according to claim 1, characterized in that, Each of the clamping arms (120) is connected to the clamp body (110) via an elastic member. When the elastic member is in the released state, the squeezing part (123) releases the reagent bottle (210) located in the accommodating cavity (111).

9. A sample dispensing system, characterized in that, include: A reagent bottle (210) includes a mixing chamber (211) and a second opening (212) communicating with the mixing chamber (211); The catheter (220) includes a blood collection end (221) and a sample application end (222) that are in communication with each other. The blood collection end (221) is inserted into the mixing chamber (211) from the second opening (212). as well as, The reagent bottle clamp (100) according to any one of claims 1 to 8 is used to squeeze the reagent bottle (210) so that the sample in the reagent bottle (210) is squeezed out from the sample dispensing end (222).

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