An integrated equipment for pulverizing and drying posterior pituitary injection for the preparation of posterior pituitary injection

Abstract

The present invention discloses an integrated equipment for pulverizing and drying posterior pituitary injection, which relates to the field of medicine and includes: a housing, a pulverizing mechanism is provided inside the housing, and the pulverizing mechanism includes a first motor and two rotating shafts; a feed inlet is provided at the top of the housing, and a discharge outlet is provided at the bottom. The rotating shafts are movably connected inside the housing, and pulverizing rods are arranged on the two rotating shafts. The pulverizing rods of the two rotating shafts cross to pulverize the posterior pituitary. The first motor is connected to one side of the housing, and the first motor drives the rotating shafts to rotate. The integrated equipment for pulverizing and drying posterior pituitary injection further includes a constant temperature drying mechanism. The integrated equipment of the present invention solves the separation of the pulverized blocks from the pulverizing structure, pulverizes first and then dries, greatly reducing the drying time.

Description

Technical Field:

[0001] The present invention relates to the field of medicine, and more specifically to an integrated equipment for pulverizing and drying the posterior pituitary for the preparation of posterior pituitary injection. Background Art:

[0002] Posterior pituitary injection is used for bleeding in the lungs, bronchi (such as hemoptysis), digestive tract bleeding (hematemesis, melena), and is applicable to obstetric induction of labor, postpartum uterine contraction, hemostasis, etc. It is also effective for intestinal paralysis after abdominal surgery.

[0003] In the preparation of the existing posterior pituitary injection, it is necessary to extract the pituitary gland of pigs. After soaking in acetone, the anterior and posterior pituitary lobes are separated. The separated posterior pituitary lobe needs to be dried. Since the structure of the posterior pituitary lobe is relatively complete, during the constant-rate drying stage, the rate of water diffusion inside the posterior pituitary lobe is greater than or equal to the surface evaporation rate. At this time, the evaporation of water occurs on the surface of the posterior pituitary lobe, and the evaporation rate is controlled by the diffusion rate of the vapor through the surrounding air film, while the drying rate depends on the temperature difference between the surrounding hot air and the posterior pituitary lobe. When the diffusion rate of water in the posterior pituitary lobe can no longer keep the surface moisture saturated, the water diffusion rate becomes the controlling factor of the drying rate. At this time, the temperature of the posterior pituitary lobe rises, and the surface begins to harden, and the drying enters the falling-rate drying stage, resulting in a very long overall drying time. For this, it is possible to pulverize first and then dry, but there is a situation where it is difficult to separate the pulverizer from the sticky and wet pulverized blocks of the posterior pituitary lobe. For this, the present invention proposes an integrated equipment for pulverizing and drying the posterior pituitary for the preparation of posterior pituitary injection, which solves the separation of the pulverized blocks from the pulverizing structure, pulverizes first and then dries, and greatly reduces the drying time. Summary of the Invention:

[0004] The present invention is to avoid the deficiencies of the above-mentioned prior art, and provides an integrated equipment for pulverizing and drying the posterior pituitary for the preparation of posterior pituitary injection, which solves the separation of the pulverized blocks from the pulverizing structure, pulverizes first and then dries, and greatly reduces the drying time.

[0005] The present invention adopts the following technical solutions to solve the technical problems:

[0006] An integrated equipment for pulverizing and drying the posterior pituitary for the preparation of posterior pituitary injection, comprising:

[0007] A housing, inside which a pulverizing mechanism is provided, and the pulverizing mechanism includes a first motor and two rotating shafts;

[0008] The top of the housing is provided with a feed inlet, and the bottom is provided with a discharge outlet. The rotating shafts are movably connected inside the housing, and pulverizing rods are arranged on the two rotating shafts. The pulverizing rods on the two rotating shafts cross to pulverize the posterior pituitary lobe. The first motor is connected to one side of the housing, and the first motor drives the rotating shafts to rotate;

[0009] The posterior pituitary pulverizing and drying integrated equipment further includes a constant-temperature drying mechanism. The top of the constant-temperature drying mechanism is provided with a feeding port. The top of the constant-temperature stirring tank is closely attached to the bottom of the pulverizing mechanism, and the feeding port is communicated with the discharging port. A plurality of groups of equally spaced heating pipes are electrically connected to the inner side of the top of the constant-temperature stirring tank.

[0010] Furthermore, the rotating shaft is of a double-layer sleeve structure. The inner layer pipe and the outer layer pipe are connected by fixing rods. A plurality of holes are correspondingly provided on the inner layer pipe and the outer layer pipe. Metal rods are inserted into the holes with a clearance fit. The top of the metal rod extends out of the outer wall of the outer layer pipe to form a pulverizing rod. The bottom of the metal rod extends into the inner part of the inner layer pipe, and the bottom of the metal rod is connected with a metal ball head. A spring is sleeved on the metal rod. One end of the spring is connected with the inner wall of the inner layer pipe, and the other end is connected with the ball head. The rotating shaft extends out of the other side of the shell, and a fixed pipe is fixedly connected to the other side of the shell. The metal ball head abuts against the outer wall of the fixed pipe. The fixed pipe is horizontally inserted into the inner layer pipe. A concave area is provided on the outer wall of the fixed pipe. The concave areas on the outer walls of the fixed pipes inside the two rotating shafts are both arranged on the other side of the opposite surface of the rotating shafts; The length of the metal rod extending out of the outer wall of the outer layer pipe is equal to the depth of the concave area.

[0011] Furthermore, the two rotating shafts are respectively a driving shaft and a driven shaft. One end of the driving shaft is fixedly connected to the motor shaft of the first motor through a coupling. Limiting gears are also meshed and connected to the surfaces of the driving shaft and the driven shaft.

[0012] Furthermore, two layers of pulverizing mechanisms are provided inside the shell. A funnel-shaped aggregate plate is provided between the two layers of pulverizing mechanisms. The aggregate port of the aggregate plate points between the two rotating shafts of the lower-layer pulverizing mechanism.

[0013] Furthermore, a stirring part is also arranged inside the constant-temperature drying mechanism. The stirring part includes a second motor, a transmission shaft and stirring fan blades. The second motor is threadedly connected to the middle of the bottom of the constant-temperature drying mechanism. The bottom of the transmission shaft is fixedly connected to the motor shaft of the second motor through a coupling. The surface of the stirring fan blades is welded and fixed to the outer wall of the transmission shaft.

[0014] The beneficial technical effects of the present invention are:

[0015] The posterior pituitary is cross-extruded and crushed by a crushing mechanism inside the housing. The raw materials remaining on the metal rod after crushing, on the other side of the rotating shaft, are cleaned by the expansion and contraction of the metal rod in the hole, using the hole to clean the rod wall of the metal rod. Cleaning on one side and crushing on the other side are carried out simultaneously, with high efficiency. The cleaned raw materials are partially cross-extruded and crushed again, and partially fall into the lower constant temperature drying mechanism. After being cross-extruded and crushed again, the hole is still used to clean the rod wall of the metal rod. The heating tubes inside the constant temperature drying mechanism heat up, so as to ensure the internal temperature of the constant temperature drying mechanism. During this process, the stepping motor is started synchronously. The stepping motor drives the transmission shaft to rotate, and the transmission shaft drives the stirring fan blades welded on the outer wall to rotate, maintaining sufficient stirring and rapid drying. First, crush and then dry, greatly reducing the drying time. Description of the Drawings:

[0016] Figure 1 It is a schematic structural diagram of an integrated equipment for crushing and drying the posterior pituitary for the preparation of posterior pituitary injection in Example 1;

[0017] Figure 2 It is a front view schematic diagram of the housing structure of the present invention;

[0018] Figure 3 It is a side view schematic diagram of the housing structure of the present invention;

[0019] Figure 4 It is a top view schematic diagram of the housing structure of the present invention;

[0020] Figure 5 It is a schematic structural diagram of an integrated equipment for crushing and drying the posterior pituitary for the preparation of posterior pituitary injection in Example 2;

[0021] Figure 6 It is a schematic diagram of the installation position of the aggregate plate;

[0022] Figure 7 It is a schematic diagram of the position of the soft scraper in Example 3;

[0023] Reference numerals in the drawings: 11, housing; 12, first motor; 13, driving shaft; 14, driven shaft; 15, limiting gear; 16, feed inlet; 17, discharge outlet; 18, inner layer tube; 19, outer layer tube; 20, fixed rod; 21, hole; 22, metal rod; 23, metal ball head; 24, spring; 25, fixed tube; 26, concave area; 27, aggregate plate; 28, constant temperature drying mechanism; 29, material inlet; 30, heating tube; 31, second motor; 32, transmission shaft; 33, stirring fan blade; 34, outlet; 35, soft scraper. Detailed Embodiments:

[0024] To enable those skilled in the art to better understand the technical solutions in this application, the technical solutions in the embodiments of this application will be clearly and completely described below in conjunction with the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments.

[0025] Example 1, as Figures 1-4 , the present invention provides an integrated equipment for pulverizing and drying posterior pituitary injection, including:

[0026] A housing 11, in which a pulverizing mechanism is provided. The pulverizing mechanism includes a first motor 12 and two rotating shafts;

[0027] A feed inlet 16 is provided at the top of the housing 11, and a discharge outlet 17 is provided at the bottom. The rotating shafts are movably connected inside the housing 11, and pulverizing rods are provided on the two rotating shafts. The pulverizing rods on the two rotating shafts cross to pulverize the posterior pituitary. The first motor 12 is connected to one side of the housing 11, and the first motor 12 drives the rotating shafts to rotate;

[0028] The integrated equipment for pulverizing and drying posterior pituitary injection further includes a constant-temperature drying mechanism 28. An inlet 29 is provided at the top of the constant-temperature drying mechanism 28. The top of the constant-temperature stirring tank is tightly attached to the bottom of the pulverizing mechanism, and the inlet 29 is communicated with the discharge outlet 17. A number of groups of equally spaced heating tubes 30 are electrically connected to the inner side of the top of the constant-temperature stirring tank;

[0029] An openable outlet 34 is provided on the side wall of the constant-temperature drying mechanism 28.

[0030] The rotating shaft is a double-layer sleeve structure. The inner layer tube 18 and the outer layer tube 19 are connected by a fixing rod 20. A number of holes 21 are correspondingly provided on the inner layer tube 18 and the outer layer tube 19. A metal rod 22 is inserted into the hole 21. The metal rod 22 is cylindrical and has a clearance fit with the hole 21. The top of the metal rod 22 extends out of the outer wall of the outer layer tube 19 to form a pulverizing rod. The bottom of the metal rod 22 extends into the inner layer tube 18, and the bottom of the metal rod 22 is connected to a metal ball head 23. A spring 24 is sleeved on the metal rod 22. One end of the spring 24 is connected to the inner wall of the inner layer tube 18, and the other end is connected to the ball head. The rotating shaft extends out of the other side of the housing 11, and a fixing tube 25 is fixedly connected to the other side of the housing 11. The metal ball head 23 abuts against the outer wall of the fixing tube 25. The fixing tube 25 is horizontally inserted into the inner layer tube 18. A concave area 26 is provided on the outer wall of the fixing tube 25. The concave areas 26 on the outer walls of the fixing tubes 25 inside the two rotating shafts are both provided on the other side of the opposite surface of the rotating shafts; The length of the metal rod 22 extending out of the outer wall of the outer layer tube 19 is equal to the depth of the concave area 26.

[0031] In this implementation: It should be noted that the inner wall of the housing 11 in this embodiment is a smooth stainless steel inner wall, and the discharge outlet 17 at the bottom is the lowest point.

[0032] In this embodiment: The function of the double-layer sleeve structure is to stabilize the metal rod 22 and maintain the stability of the metal rod 22 during its telescopic movement in the hole 21.

[0033] In this embodiment: The pituitary posterior lobe after being soaked in acetone is taken out and placed into the housing 11 through the feed port 16 at the top of the housing 11. The first motor 12 is turned on. When the rotating shaft of the double-layer sleeve structure is working, the fixedly connected inner tube 18 and outer tube 19 rotate simultaneously. The fixed tube 25 inside the inner tube 18 is fixedly connected to the other side of the housing 11 and does not rotate. Affected by the elastic force of the spring 24, the metal ball head 23 at the bottom of the metal rod 22 will move along the outer wall of the fixed tube 25 and press against the outer wall of the fixed tube 25. The length of the top of the metal rod 22 extending out of the outer wall of the outer tube 19 is slightly less than the distance between the two rotating shafts. The metal rod 22 between the two rotating shafts forms a dislocation to cross-crush the pituitary posterior lobe. The concave areas 26 on the outer walls of the fixed tubes 25 inside the two rotating shafts are all arranged on the other side of the opposite surface of the rotating shafts. And the metal ball head 23 of the metal rod 22 presses against the outer wall of the fixed tube 25, and the length of the top of the metal rod 22 extending out of the outer wall of the outer tube 19 is less than the distance between the two rotating shafts. When the metal rod 22 rotates to the other side, affected by the elastic force of the spring 24, the metal ball head 23 slides into and then out of the concave area 26. At this time, the telescopic movement of the metal rod 22 in the hole 21 is used to clean the rod wall of the metal rod 22 by the hole 21. Cleaning on one side and crushing on the other side are carried out simultaneously, with high efficiency.

[0034] Further, the two rotating shafts are respectively a driving shaft 13 and a driven shaft 14. One end of the driving shaft 13 is fixedly connected to the motor shaft of the first motor 12 through a coupling. The surfaces of the driving shaft 13 and the driven shaft 14 are also meshed with a limiting gear 15.

[0035] In this embodiment, the first motor 12 on the outside drives the driving shaft 13 to rotate. Due to the meshing of the two groups of limiting gears 15, under the gear transmission, the driven shaft 14 rotates in the opposite direction along the rotation direction of the driving shaft 13, thereby ensuring that the metal rods 22 on their respective surfaces press the raw materials inward.

[0036] Further, a stirring part is also arranged inside the constant temperature drying mechanism 28. The stirring part includes a second motor 31, a transmission shaft 32 and stirring fan blades 33. The second motor 31 is threadedly connected to the middle of the bottom of the constant temperature drying mechanism 28. The bottom of the transmission shaft 32 is fixedly connected to the motor shaft of the second motor 31 through a coupling. The surface of the stirring fan blades 33 is fixedly welded to the outer wall of the transmission shaft 32.

[0037] In this embodiment: The heating tubes 30 inside the constant-temperature drying mechanism 28 are heated to ensure the internal temperature of the constant-temperature drying mechanism 28. During this process, the stepping motor is started synchronously. The stepping motor drives the transmission shaft 32 to rotate, and the transmission shaft 32 drives the stirring fan blades 33 welded to the outer wall to rotate, maintaining sufficient stirring and rapid drying. First, it is crushed and then dried, significantly reducing the drying time.

[0038] Embodiment 2, as Figures 3-6 , on the basis of Embodiment 1, two layers of crushing mechanisms are provided inside the housing 11, and a funnel-shaped aggregate plate 27 is provided between the two layers of crushing mechanisms. The aggregate opening of the aggregate plate 27 points between the two rotating shafts of the lower-layer crushing mechanism.

[0039] In this embodiment: The raw materials after being cleaned by the upper-layer crushing mechanism are partially crushed again by cross extrusion and partially fall to the lower-layer crushing mechanism. After being crushed again by cross extrusion, the hole 21 is still used to clean the rod wall of the metal rod 22, increasing the crushing effect.

[0040] It should be noted that the present invention is to reduce the drying time, and it adopts crushing first and then drying. It is not necessary to completely crush. Therefore, incomplete crushing does not affect the effect of shortening the drying time after crushing.

[0041] And to solve the problem of incomplete crushing, this embodiment has carried out crushing through a double-layer crushing mechanism.

[0042] Embodiment 3, as Figure 7 , on the basis of Embodiment 2, in order to more thoroughly remove the crushed blocks on the surface of the rotating shaft and the crushing rod.

[0043] Two soft scraping plates 35 are provided on the inner wall of the housing, and the two soft scraping plates face downwards and are respectively in contact with the other side of the opposite surface of the rotating shaft. That is, on the rotating shaft pointing to the horizontal position of the concave area.

[0044] The raw materials remaining on the metal rod after crushing are on the other side of the rotating shaft. Through the telescoping of the metal rod in the hole, the hole is used to clean the rod wall of the metal rod. Since the length of the metal rod extending out of the outer wall of the outer layer tube is equal to the depth of the concave area, at this time, the crushing rod is completely retracted into the rotating shaft. Using this gap, the soft scraping plate scrapes off the crushed blocks on the rotating shaft. At the same time, the two soft scraping plates are arranged facing downwards, and the crushed blocks fall downwards without residue.

[0045] It should be noted that the inside of the inner layer tube of the spring in the above embodiment is always in a compressed state, so that the crushing rod can continuously abut against the surface of the fixed tube in the concave area, thereby achieving the purpose of the telescoping of the metal rod.

[0046] In the present invention, unless there are specific regulations and limitations, the features are interlaced with each other and do not necessarily exist independently. The above display and description include the basic principles, main features and advantages of the present invention. Those skilled in the art should know that the present invention is not limited to the limitations of the above embodiments, and the above embodiments and the description are only preferred examples of the present invention, rather than being used to limit the present invention to be the only option. Under the requirements of the spirit and scope of the invention, the present invention can be further changed and optimized, and the improvements and optimizations made to the present invention all fall within the scope of the present invention claimed. The specific scope claimed by the present invention is defined by the appended claims and their equivalents.

Claims

1. An integrated equipment for pulverizing and drying posterior pituitary injection, characterized in that, it includes: A housing, inside which there is a pulverizing mechanism, and the pulverizing mechanism includes a first motor and two rotating shafts; The top of the housing is provided with a feed inlet, and the bottom is provided with a discharge outlet. The rotating shafts are movably connected inside the housing, and pulverizing rods are arranged on the two rotating shafts. The pulverizing rods on the two rotating shafts cross to pulverize the posterior pituitary. The first motor is connected to one side of the housing, and the first motor drives the rotating shafts to rotate; The integrated equipment for pulverizing and drying posterior pituitary injection also includes a constant-temperature drying mechanism. The top of the constant-temperature drying mechanism is provided with a feeding port. The top of the constant-temperature stirring tank is closely attached to the bottom of the pulverizing mechanism, and the feeding port is communicated with the discharge outlet. Several groups of equally spaced heating tubes are electrically connected to the inner side of the top of the constant-temperature stirring tank; The rotating shaft is a double-layer sleeve structure. The inner layer tube and the outer layer tube are connected by fixing rods. Corresponding holes are provided on the inner layer tube and the outer layer tube. Metal rods are inserted into the holes with a clearance fit. The top of the metal rod extends out of the outer wall of the outer layer tube to form a pulverizing rod. The bottom of the metal rod extends into the inner layer tube, and the bottom of the metal rod is connected to a metal ball head. A spring is sleeved on the metal rod. One end of the spring is connected to the inner wall of the inner layer tube, and the other end is connected to the ball head. The rotating shaft extends out of the other side of the housing, and a fixed tube is fixedly connected to the other side of the housing. The metal ball head abuts against the outer wall of the fixed tube. The fixed tube is horizontally inserted into the inner layer tube. A concave area is provided on the outer wall of the fixed tube. The concave areas on the outer walls of the fixed tubes inside the two rotating shafts are both arranged on the other side of the opposite surface of the rotating shafts; The length of the metal rod extending out of the outer wall of the outer layer tube is equal to the depth of the concave area; Two soft scraping plates are provided on the inner wall of the housing. The two soft scraping plates face down and are respectively in contact with the other side of the opposite surface of the rotating shafts, that is, on the rotating shafts pointing to the horizontal position of the concave area.

2. The integrated equipment for pulverizing and drying posterior pituitary injection according to claim 1, characterized in that, The two rotating shafts are respectively a driving shaft and a driven shaft. One end of the driving shaft is fixedly connected to the motor shaft of the first motor through a coupling, and a limiting gear is also meshed and connected to the surfaces of the driving shaft and the driven shaft.

3. The integrated equipment for pulverizing and drying posterior pituitary injection according to claim 1, characterized in that, Two layers of pulverizing mechanisms are provided inside the housing, and a funnel-shaped aggregate plate is provided between the two layers of pulverizing mechanisms. The aggregate port of the aggregate plate points to the space between the two rotating shafts of the lower layer of pulverizing mechanism.

4. The integrated equipment for pulverizing and drying posterior pituitary injection according to claim 1, characterized in that, A stirring part is also arranged inside the constant-temperature drying mechanism. The stirring part includes a second motor, a transmission shaft and stirring fan blades. The second motor is threadedly connected to the middle of the bottom of the constant-temperature drying mechanism. The bottom of the transmission shaft is fixedly connected to the motor shaft of the second motor through a coupling, and the surface of the stirring fan blades is welded and fixed to the outer wall of the transmission shaft.

Images