A suspension emulsion containing spirotetramat and pyridalyl, and a preparation method and application thereof

Abstract

The present application belongs to the field of pesticides, and relates to a kind of insecticidal composition, specifically to a kind of suspension emulsion containing spirotetramat and pyridalyl and its preparation method and application.The present application realizes the preparation of the suspension emulsion of spirotetramat and pyridalyl, has higher insecticidal effect, reduces the amount of insecticide and the frequency of pesticide application, thereby reduces the cost of pesticide, is safe and environmentally friendly;The present application scientifically selects and screens the auxiliary system, finally obtains the system with the best matching degree among components, especially the screening and combination of dispersing agent, emulsifier, solvent and cosolvent, greatly reduces the processing difficulty of dosage form, improves the stability of dosage form, has the advantages of good emulsification and dispersion, high suspension rate, effectively solves the problems of creaming, flocculation, particle size enlargement and crystallization during sample storage, etc.Through the screening of dispersing agent, solvent and cosolvent, the obtained product does not have the problem of crystallization after long-term storage, and still has excellent efficacy after long-term storage.

Description

Technical Field

[0001] This invention belongs to the field of pesticides and relates to an insecticidal composition, specifically to a suspension emulsion containing spirotetramat and pyriproxyfen, its preparation method, and its application. Background Technology

[0002] Spirotetracycline, in its pure form, is a light beige powder with no special odor. Its decomposition temperature is 235℃. Melting point: 142℃. Solubility (20℃): 33.4 mg / L in water (pH 6.0~6.3), and in organic solvents (g / L): 0.055 in n-hexane, 44 in ethanol, 60 in toluene, 67 in ethyl acetate, 100~120 in acetone, 200-300 in dimethyl sulfoxide, and >600 in dichloromethane. LogP = 2.51 (pH = 7). At pH 4: DT50 = 32.5 days; at pH 9: DT50 = 0.32 days (25℃).

[0003] Pyriproxypyridine, in its pure form, is a crystalline solid with a melting point of 45-47℃, a vapor pressure (20℃) of 0.29 × 10⁻³ Pa, and a relative density of 1.32 g / cm³. Its solubility (25℃) is: water 0.4 mg / L, hexane 400 g / L, methanol 200 g / L, and xylene 500 g / L. It is stable at 50℃ and within a pH range of 4 to 9.

[0004] Suspension emulsions have advantages such as being environmentally friendly, having high efficacy, not requiring tank mixing adjuvants, and being easy to use; however, they also have the disadvantage of poor stability.

[0005] Currently, there are no records of preparing spirotetramat and pyriproxyfen into suspension emulsions. Summary of the Invention

[0006] To address the technical challenges of existing suspension emulsions, such as easy crystallization during preparation, which affects wet sieving and dispersion stability, and prevents normal use, this invention provides a suspension emulsion containing spirotetramat and pyriproxyfen.

[0007] The present invention also provides a method for preparing a suspension emulsion containing spirotetramat and pyriproxyfen.

[0008] Another object of the present invention is to provide the application of the above-mentioned suspension emulsion containing spirotetramat and pyriproxyfen.

[0009] The technical solution adopted by the present invention to achieve the above objectives is as follows:

[0010] This invention provides a suspension emulsion composed of the following components by weight percentage: 8-24% pharmaceutical active ingredient, 2.5-11.5% dispersant, 1.5-10% emulsifier, 0.1-2.5% thickener, 0.1-0.4% defoamer, 0.1-0.4% preservative, 1-6% antifreeze, 6-20% solvent, 0.5-5% cosolvent, and water to make up to 100%.

[0011] The first active component of the drug is spirotetramat, and the second active component is pyriproxyfen.

[0012] Preferably, the mass ratio of the first active component to the second active component is (7-18):(1-6).

[0013] In the suspension emulsion system provided by the present invention, the dispersant is one or more of the following: polyoxyethylene-polyoxypropylene copolymer, sulfonate, phosphate ester, sulfate ester, polycarboxylate, and styrene-maleic anhydride copolymer polyether dimethylamine salt; preferably, the dispersant is polyoxyethylene-polyoxypropylene copolymer, sulfonate, phosphate ester, polycarboxylate, and styrene-maleic anhydride copolymer polyether dimethylamine salt; preferably, the dispersant is a mixture of polyoxyethylene-polyoxypropylene copolymer, phosphate ester, and styrene-maleic anhydride copolymer polyether dimethylamine salt in a mass ratio of (1-5):(1-4):(0.5-2.5); most preferably, it is a mixture in a mass ratio of 3:2:1.

[0014] Further, the emulsifier is one or more of the following: oleyl polyether, polyoxyethylene sorbitan monooleate, tristyrene-phenylphenol polyoxyethylene ether phosphate triethanolamine salt, polyacrylate, nonionic hydroxyl polyethylene oxide block copolymer, and alkylbenzene sulfonate; preferably, the emulsifier is oleyl polyether, polyacrylate, nonionic hydroxyl polyethylene oxide block copolymer, and alkylbenzene sulfonate; preferably, the emulsifier is a mixture of alkylbenzene sulfonate, oleyl polyether, and polyacrylate in a mass ratio of (0.5-3):(0.5-4):(0.5-3); most preferably, it is a mixture in a mass ratio of 1:2:1.

[0015] In the suspension emulsion system provided by this invention, the thickener is one or more of magnesium aluminum silicate, xanthan gum, and fumed silica; preferably, magnesium aluminum silicate and xanthan gum are mixed in a mass ratio of 1:0.1; the defoamer is one or more of organosilicon, polyether-modified organosilicon, alcohol, or polyether type, preferably, the defoamer is organosilicon, and the most preferred addition amount is 0.2%; the preservative is one or more of sodium benzoate, 1,2-benzisothiazol-3-one, isothiazolinone, and paraformaldehyde, preferably, the preservative is 1,2-benzisothiazol-3-one, and the most preferred addition amount is 0.1%; the antifreeze is one or more of ethylene glycol, propylene glycol, polyethylene glycol, or glycerol, preferably, the antifreeze is ethylene glycol, and the most preferred addition amount is 4%.

[0016] In the suspension emulsion system provided by the present invention, the organosilicon includes, but is not limited to, one or more of polydimethylsiloxane, fluorosiloxane, and ethylene glycol siloxane; the polyether-modified organosilicon includes, but is not limited to, one or more of polyether polydimethylsiloxane copolymer, polyether polyfluorosiloxane copolymer, and polyether ethylene glycol siloxane copolymer; the alcohols include, but are not limited to, one or more of diethylhexanol, isooctanol, isoamyl alcohol, and diisobutylmethanol; and the polyether type includes, but is not limited to, one or more of glycerol polyether and polyoxyethylene polyoxypropylene glycerol ether.

[0017] Further, the solvent is one or more of solvent oil 200#, solvent oil 150#, methyl cis-9-octadecenoate, N,N-dimethyldecanoate, and isoflurane; preferably, the solvent is solvent oil 200#, solvent oil 150#, and methyl cis-9-octadecenoate; most preferably, the solvent is methyl cis-9-octadecenoate; the co-solvent is one or more of solvent oil 200#, solvent oil 150#, NMP, cyclohexanone, and xylene; preferably, the co-solvent is solvent oil 200# and NMP; most preferably, the solvent is solvent oil 200#.

[0018] The present invention also provides a method for preparing the above-mentioned suspension emulsion, comprising the following steps:

[0019] (1) Mix water, dispersant, thickener, defoamer, preservative, and antifreeze, and then thoroughly shear and disperse to obtain a mixture;

[0020] (2) Add spirotetramat technical to the mixture in a dispersed state, shear and grind to obtain a sand-milled phase; then add solvent and co-solvent, then add pyriproxyfen technical, keep warm and stir until clear, add emulsifier and continue stirring until clear and transparent to obtain a dissolved phase; mix the sand-milled phase and the dissolved phase, shear thoroughly to obtain a suspension emulsion containing spirotetramat and pyriproxyfen.

[0021] Furthermore, in step (1), the shearing and dispersion time is 20-40 minutes; in step (2), the particle size of the sand-milled phase is D90≤4.0µm; the heat preservation temperature is 30-45℃; and the sufficient shearing time is 30min.

[0022] The present invention also provides an application of the above-mentioned suspension emulsion in the control of pests on vegetables, fruit trees, rice and cotton.

[0023] In the preparation method provided by the present invention, each material is subjected to high-speed shearing at a shearing speed of 1000-10000 r / min.

[0024] In the above preparation method, grinding can be performed using any grinding method disclosed in the prior art, such as grinding under zirconia bead milling media. After grinding, the particle size is detected using a laser particle size analyzer until the particle size D90 ≤ 4.0 µm.

[0025] The preparation method provided by this invention addresses the issue of spirotetramat and pyriproxyfen. Pyriproxyfen has a lower melting point; if used directly in sand milling, local temperatures may exceed the melting point, or heat storage for a certain period may cause the material to become pasty. Therefore, it is more suitable as a solubilizing phase in a suspension emulsion. Physicochemical properties show that spirotetramat also has a certain solubility in some solvents. Inappropriate solvent selection or improper dispersant formulation can easily lead to spirotetramat precipitation. Therefore, the selection of dispersants and solvents / cosolvents is particularly important. This invention, through the screening and matching of dispersants and solvents / cosolvents, significantly reduces the difficulty of dosage form processing, allowing for stable compounding of the two active ingredients without problems such as pasting or crystallization. The resulting product has advantages such as good emulsification and dispersibility, resistance to thickening or clumping, minimal residue after pouring, and high stability under cold and hot storage conditions.

[0026] The beneficial effects of this invention are as follows:

[0027] (1) This invention realizes the preparation of spirotetramat and pyriproxyfen suspension emulsion, which has a high insecticidal effect, reduces the amount of insecticide used and the frequency of application, thereby reducing the cost of the pesticide and making it safe and environmentally friendly.

[0028] (2) This invention scientifically selects and screens the adjuvant system, ultimately obtaining a system with optimal matching between components. In particular, the screening and combination of dispersants, emulsifiers, solvents, and cosolvents greatly reduces the processing difficulty of the dosage form and improves its stability. It has the advantages of good emulsification and dispersibility and high suspension rate, effectively solving problems such as sample storage, paste formation, flocculation, particle size growth, and crystallization. Through the screening of dispersants, solvents, and cosolvents, the obtained product does not have crystallization problems after long-term storage, and its efficacy remains excellent after long-term storage. Detailed Implementation

[0029] The following embodiments are further illustrations of the present invention and serve as explanations of the technical content of the present invention, but the essence of the present invention is not limited to the embodiments described below.

[0030] Unless otherwise specified, all percentages below are by weight.

[0031] Example 1: Spirotetramethrin and Pyriproxyfen 16% Suspension Emulsion

[0032] The formula is as follows: 11.8% spirotetramat, 4.2% pyriproxyfen, 3.0% polyoxyethylene-polyoxypropylene copolymer + 2.0% phosphate ester + 1.0% styrene-maleic anhydride copolymer polyether dimethylamine salt, 1% alkylbenzene sulfonate + 2% oleate polyether + 1% polyacrylate, 1% magnesium aluminum silicate + 0.1% xanthan gum, 0.2% polydimethylsiloxane, 0.1% 1,2-benzisothiazol-3-one, 4% ethylene glycol, 17% cis-9-octadecenoate + 2% solvent oil 200# and the balance water.

[0033] The preparation method is as follows: Dispersion medium, dispersant, thickener, defoamer, preservative, and antifreeze are added to a reaction vessel and fully sheared and dispersed for 20-40 minutes. While still dispersed, spirotetramat technical is added to the reaction vessel and sheared for 20-30 minutes. The mixture is then ground until the particle size D90 ≤ 4.0 µm, yielding a milled phase. Solvent and co-solvent are added to the reaction vessel, followed by pyriproxyfen technical. The mixture is kept at 30-45℃ and stirred until clear. An emulsifier is added, and stirring continues until clear and transparent, yielding a dissolved phase. The milled phase and dissolved phase are mixed and fully sheared for 30 minutes to obtain a suspension containing spirotetramat and pyriproxyfen.

[0034] Example 2: Spirotetramethrin and pyriproxyfen 8% suspension emulsion

[0035] The formula is as follows: 7% spirotetramat, 1% pyriproxyfen, 3.0% polyoxyethylene-polyoxypropylene copolymer + 2.0% phosphate ester + 1.0% styrene-maleic anhydride copolymer polyether dimethylamine salt, 1% alkylbenzene sulfonate + 2% oleate polyether + 1% polyacrylate, 1% magnesium aluminum silicate + 0.1% xanthan gum, 0.2% polydimethylsiloxane, 0.1% 1,2-benzisothiazol-3-one, 4% ethylene glycol, 17% cis-9-octadecenoate methyl ester + 2% solvent oil 200# and the balance water.

[0036] The preparation method is the same as in Example 1.

[0037] Example 3: Spirotetramethrin and pyriproxyfen 11.5% suspension emulsion

[0038] The formula is as follows: 8.5% spirotetramat, 3% pyriproxyfen, 2% sulfonate + 2.0% polycarboxylate, 0.5% alkylbenzene sulfonate + 1.5% oleoyl polyether + 1% polyacrylate, 1% fumed silica + 0.1% xanthan gum, 0.2% polyether polydimethylsiloxane copolymer, 0.1% sodium benzoate, 4% ethylene glycol, 5% solvent oil 200#, and the balance being water.

[0039] The preparation method is the same as in Example 1.

[0040] Example 4: Spirotetramethrin and pyriproxyfen 13% suspension emulsion

[0041] The formula is as follows: 11% spirotetramat, 2% pyriproxyfen, 3.0% polyoxyethylene-polyoxypropylene copolymer + 2.0% polycarboxylate, 1.5% alkylbenzene sulfonate + 1.0% polyoxyethylene-polyoxypropylene copolymer, 0.15% xanthan gum, 0.1% isooctyl alcohol, 0.05% 1,2-benzisothiazol-3-one, 2% propylene glycol, 15% methyl cis-9-octadecenoate, and the balance being water.

[0042] The preparation method is the same as in Example 1.

[0043] Example 5: Spirotetramethrin and pyriproxyfen 19.5% suspension emulsion

[0044] The formula is as follows: 14% spirotetramat, 5.5% pyriproxyfen, 1.0% phosphate ester + 2.0% styrene-maleic anhydride copolymer polyether dimethylamine salt, 4% polyoxyethylene-polyoxypropylene copolymer, 0.5% magnesium aluminum silicate + 0.1% xanthan gum, 0.1% fluorosiloxane, 0.05% isothiazolinone, 4% glycerol, 15% cis-9-octadecenoate + 2% NMP and the balance being water.

[0045] The preparation method is the same as in Example 1.

[0046] Example 6: Spirotetramethrin and Pyriproxyfen 21% Suspension Emulsion

[0047] The formula is as follows: 15% spirotetramat, 6% pyriproxyfen, 2.0% polyoxyethylene-polyoxypropylene copolymer + 3.0% phosphate ester + 2.0% styrene-maleic anhydride copolymer polyether dimethylamine salt, 2% alkylbenzene sulfonate + 3% oleate polyether + 2% polyacrylate, 0.15% xanthan gum, 0.3% fluorosiloxane, 0.1% 1,2-benzisothiazol-3-one, 4% glycerol, 5% solvent oil 200# + 1% cyclohexanone, and the balance being water.

[0048] The preparation method is the same as in Example 1.

[0049] Example 7 Spirotetramethrin and Pyriproxyfen 24% Suspension Emulsion

[0050] The formula is as follows: 18% spirotetramat, 6% pyriproxyfen, 3.0% polyether dimethylamine salt of styrene-maleic anhydride copolymer, 1% alkylbenzene sulfonate + 2% polyoxyethylene-polyoxypropylene copolymer + 1% polyacrylate, 1% magnesium aluminum silicate + 0.2% xanthan gum, 0.1% polyether polyfluorosiloxane copolymer, 0.1% isothiazolinone, 4% polyethylene glycol, 10% solvent oil 200# and the balance water.

[0051] The preparation method is the same as in Example 1.

[0052] Example 8: Spirotetramethrin and Pyriproxyfen 21% Suspension Emulsion

[0053] The formula is as follows: 18% spirotetramat, 3% pyriproxyfen, 1.5% sulfonate + 2.0% phosphate ester + 1.0% styrene-maleic anhydride copolymer polyether dimethylamine salt, 1.5% alkylbenzene sulfonate + 2% oleate polyether, 1% magnesium aluminum silicate + 0.1% xanthan gum, 0.2% polyether polydimethylsiloxane copolymer, 0.1% paraformaldehyde, 2% ethylene glycol, 10% cis-9-octadecenoate methyl ester + 2% solvent oil 200# and the balance water.

[0054] The preparation method is the same as in Example 1.

[0055] Example 9: Spirotetramethrin and Pyriproxyfen 16% Suspension Emulsion

[0056] The formula is as follows: 11.8% spirotetramat, 4.2% pyriproxyfen, 3.0% polyoxyethylene-polyoxypropylene copolymer + 2.0% phosphate ester + 1.0% styrene-maleic anhydride copolymer polyether dimethylamine salt, 1% alkylbenzene sulfonate + 2% oleate polyether + 1% polyacrylate, 1% magnesium aluminum silicate + 0.1% xanthan gum, 0.2% polydimethylsiloxane, 0.1% 1,2-benzisothiazol-3-one, 4% ethylene glycol, 5% solvent oil 200#, and the balance being water.

[0057] The preparation method is the same as in Example 1.

[0058] Example 10 Spirotetramethrin and Pyriproxyfen 16% Suspension Emulsion

[0059] The formula is as follows: 11.8% spirotetramat, 4.2% pyriproxyfen, 2.0% polyoxyethylene-polyoxypropylene copolymer + 2.0% polycarboxylate, 1% alkylbenzene sulfonate + 2% oleoyl polyether + 1% polyacrylate, 1% magnesium aluminum silicate + 0.1% xanthan gum, 0.2% ethylene glycol siloxane, 0.1% 1,2-benzisothiazol-3-one, 4% ethylene glycol, 17% methyl cis-9-octadecenoate + 2% solvent oil 200# and the balance being water.

[0060] The preparation method is the same as in Example 1.

[0061] Comparative Example 1: Spirotetramethrin and Pyriproxyfen 16% Suspension Emulsion

[0062] The formula is as follows: 13% spirotetramat, 3% pyriproxyfen, 2% sulfate, 3% polyoxyethylene sorbitan monooleate, 0.2% xanthan gum, 0.1% diethylhexanol, 0.1% paraformaldehyde, 4% ethylene glycol, 3% cyclohexanone, and the balance being water.

[0063] The preparation method is the same as in Example 1.

[0064] Comparative Example 2: Spirotetramethrin and Pyriproxyfen 13% Suspension Emulsion

[0065] The formula is as follows: 9% spirotetramat, 4% pyriproxyfen, 2% sulfate + 2.0% polyphosphate, 4% tristyrene-phenylphenol polyoxyethylene ether phosphate triethanolamine salt, 2% silica + 0.1% xanthan gum, 0.2% polyether glycol siloxane copolymer, 0.1% paraformaldehyde, 4% ethylene glycol, 3% NMP and the balance water.

[0066] The preparation method is the same as in Example 1.

[0067] Comparative Example 3: Spirotetramethrin and Pyriproxyfen 16% Suspension Emulsion

[0068] The formula is as follows: 11.8% spirotetramat, 4.2% pyriproxyfen, 3.0% polyoxyethylene-polyoxypropylene copolymer + 2.0% phosphate ester + 1.0% styrene-maleic anhydride copolymer polyether dimethylamine salt, 1% alkylbenzene sulfonate + 2% oleate polyether + 1% polyacrylate, 1% magnesium aluminum silicate + 0.1% xanthan gum, 0.2% polydimethylsiloxane, 0.1% 1,2-benzisothiazol-3-one, 4% ethylene glycol, and the balance being water.

[0069] The preparation method is as follows: the dispersion medium, dispersant, thickener, defoamer, preservative, antifreeze and emulsifier are added to the reaction vessel and fully sheared and dispersed for 20-40 minutes; while in the dispersed state, spirotetramat technical and pyriproxyfen technical are added to the reaction vessel and sheared for 20-30 minutes, and then ground until the particle size D90 of the mixture is ≤4.0µm, and the suspension containing spirotetramat and pyriproxyfen is directly discharged to obtain the suspension emulsion.

[0070] Effect Example

[0071] (a) The performance of the suspension emulsions prepared in the above examples and comparative examples was tested, and the results are shown in Table 1 below. Among them, the dispersion stability was tested according to the CIPAC MT180 pesticide dispersion stability test method, the pouring property was tested according to the CIPAC MT148.1 pesticide pouring property test method, and the wet sieving was tested according to the CIPAC MT1805 pesticide wet sieving test method.

[0072] Table 1. Performance of suspension emulsion products prepared by combining spirotetramat and pyriproxyfen.

[0073]

[0074]

[0075] Table 1 shows that Comparative Examples 1 and 2 exhibited poor fluidity at room temperature and poor adaptability to different water qualities. Their quality was unsatisfactory after both cold and hot storage. The samples were intolerant to high and low temperatures ranging from 0℃ to 54℃. After 7 days of storage at 0℃, the samples crystallized and formed a paste upon returning to room temperature; after 14 days of storage at 54℃, the samples lost fluidity and crystallized upon returning to room temperature. Example 1 showed stable quality before and after cold and hot storage and was adaptable to different water qualities. Example 2 showed slightly worse wet sieving after hot storage, and its pourability was not as good as Example 1. Examples 3-7 showed varying degrees of water separation after hot storage, and their wet sieving performance deteriorated. Their adaptability to different water qualities was also not as good as Example 1. Example 7 showed crystallization after both cold and hot storage. Example 8 showed demulsification and stratification after hot storage, with crystal precipitation and poor quality. Example 9 showed crystallization after changing the co-solvent. Example 10 showed poor fluidity and a small amount of crystallization after hot storage after changing the dispersant. Comparative Example 3, without co-solvent, showed crystallization, affecting wet sieving. In summary, the comparison revealed that Example 1 had the best quality, followed by Example 2. The selection of optimal additives plays a crucial role in product quality.

[0076] (ii) Efficacy test

[0077] This experiment was conducted in a tomato field belonging to a farmer in the suburbs of Weifang City, Shandong Province. Pesticide compositions from Examples 1-10 and Comparative Examples 1-3 were sprayed in different planting areas. All pesticides used were prepared by the company, and water was used as a control instead of the pesticide compositions. The whitefly infestation index was investigated before application. Application was carried out at the initial stage of infestation, and the infestation index was investigated at 1, 3, and 7 days after application. The control efficacy was calculated using the following formula, and the results are shown in Table 2.

[0078]

[0079] Table 2

[0080]

Claims

1. A suspension emulsion, characterized in that, It consists of the following components by weight percentage: 8-24% active pharmaceutical ingredient, 2.5-11.5% dispersant, 1.5-10% emulsifier, 0.1-2.5% thickener, 0.1-0.4% defoamer, 0.1-0.4% preservative, 1-6% antifreeze, 6-20% solvent, 0.5-5% cosolvent, and water to make up to 100%. The first active component of the drug is spirotetramat, and the second active component is pyriproxyfen. The mass ratio of the first active component to the second active component is (7-18):(1-6); The dispersant is a mixture of polyoxyethylene-polyoxypropylene copolymer, phosphate ester, styrene-maleic anhydride copolymer, and polyether dimethylamine salt in a mass ratio of (1-5):(1-4):(0.5-2.5); The solvent is methyl cis-9-octadecenoate.

2. The suspension emulsion according to claim 1, characterized in that, The emulsifier is one or more of the following: oleic acid polyether, polyoxyethylene sorbitan monooleate, tristyrene-phenylphenol polyoxyethylene ether phosphate triethanolamine salt, polyacrylate, nonionic hydroxyl polyethylene oxide block copolymer, and alkylbenzene sulfonate.

3. The suspending emulsion according to claim 2, characterized in that, The emulsifier is an oleic ester polyether, polyacrylate, nonionic hydroxyl polyethylene oxide block copolymer, or alkylbenzene sulfonate.

4. The suspending emulsion according to claim 3, characterized in that, The emulsifier is a mixture of alkylbenzene sulfonate, oleic ester polyether, and polyacrylate in a mass ratio of (0.5-3):(0.5-4):(0.5-3).

5. The suspending emulsion according to claim 4, characterized in that, The alkylbenzene sulfonate, oleyl ester polyether, and polyacrylate are mixed in a mass ratio of 1:2:

1.

6. The suspension emulsion according to claim 1, characterized in that, The thickener is one or more of magnesium aluminum silicate, xanthan gum, and fumed silica; the defoamer is one or more of organosilicon, polyether-modified organosilicon, alcohol, or polyether type; the organosilicon is one or more of polydimethylsiloxane, fluorosiloxane, and ethylene glycol siloxane; the polyether-modified organosilicon is one or more of polyether polydimethylsiloxane copolymer, polyether polyfluorosiloxane copolymer, and polyether ethylene glycol siloxane copolymer; the alcohol is one or more of diethylhexanol, isooctanol, isoamyl alcohol, and diisobutylmethanol; the polyether type is one or more of glycerol polyether and polyoxyethylene polyoxypropylene glycerol ether; the preservative is one or more of sodium benzoate, 1,2-benzisothiazol-3-one, isothiazolinone, and paraformaldehyde; the antifreeze is one or more of ethylene glycol, propylene glycol, polyethylene glycol, or glycerol.

7. The suspending emulsion according to claim 6, characterized in that, The thickener is a mixture of magnesium aluminum silicate and xanthan gum in a mass ratio of 1:0.1; the preservative is 1,2-benzisothiazol-3-one; and the antifreeze is ethylene glycol.

8. The suspending agent according to claim 1, characterized in that, The co-solvent is one or more of solvent oil 200#, solvent oil 150#, NMP, cyclohexanone, and xylene.

9. The suspending agent according to claim 8, characterized in that, The co-solvent is solvent oil 200# and NMP.

10. The suspending agent according to claim 9, characterized in that, The co-solvent is solvent oil 200#.

11. A method for preparing a suspension emulsion as described in any one of claims 1-10, characterized in that, Includes the following steps: (1) Mix water, dispersant, thickener, defoamer, preservative, and antifreeze, and then thoroughly shear and disperse to obtain a mixture; (2) Add spirotetramat technical to the mixture in a dispersed state, shear and grind to obtain a sand-milled phase; then add solvent and co-solvent, then add pyriproxyfen technical, keep warm and stir until clear, add emulsifier and continue stirring until clear and transparent to obtain a dissolved phase; mix the sand-milled phase and the dissolved phase, shear thoroughly to obtain a suspension emulsion containing spirotetramat and pyriproxyfen.

12. The preparation method according to claim 11, characterized in that, In step (1), the shearing and dispersion time is 20-40 minutes; in step (2), the particle size of the sand-milled phase is D90≤4.0µm; the heat preservation temperature is 30-45℃; and the sufficient shearing time is 30 minutes.

13. The application of a suspension emulsion as described in any one of claims 1-10 in the control of pests on vegetables, fruit trees, rice, and cotton.

Images