Nanofiber containing artemisia extract and method and apparatus for producing same

Abstract

The application provides a nano fiber containing artemisia extract and a production method and equipment thereof, and relates to the field of textile technology. The nano fiber containing artemisia extract comprises a fiber body, and the fiber body is composed of a core layer and a skin layer wrapped on the outer wall of the core layer. In the application, the artemisia extract is mixed with a slow-release agent, encapsulated into a porous microsphere to form a drug-loaded porous microsphere, and after water washing to remove the pore-forming agent, a plurality of micro pores are formed on the surface of the skin layer, the artemisia extract is not in direct contact with the skin, but can be carried by the porous microsphere, and is slowly released through the micro pores, and is not afraid of water washing and friction, so that the long-acting effect is greatly improved. Through the connection of the inner box, the clean water tank, the water washing agent providing tank, the inner box and the recycling tank, after the fiber semi-finished product is placed on the object table, the water washing agent can be used to remove the pore-forming agent, the clean water can be used to wash, and then the low-temperature drying action can be completed after the clean water washing action by cooperating with the electric heating layer.

Description

Technical Field

[0001] This invention relates to the field of textile technology, specifically to a nanofiber containing Artemisia argyi extract and its production method and equipment. Background Technology

[0002] Artemisia argyi is a perennial herb. Its leaves are used medicinally; they are warm in nature, bitter in taste, non-toxic, and purely yang in nature. They are believed to unblock the twelve meridians and possess effects such as restoring yang, regulating qi and blood, dispelling dampness and cold, stopping bleeding, and calming the fetus. They are also commonly used in acupuncture. Regarding the specific function of releasing negative ions, if artemisia argyi extract is selected and incorporated into polyester melt, it can be melt-spun into artemisia argyi fiber. Such fiber retains the advantages of artemisia argyi, and fabrics made from it possess the health-preserving, nourishing, and medicinal functions of artemisia argyi. This fully utilizes the excellent health-preserving properties of artemisia argyi and can be widely applied in the textile, clothing, and health product industries.

[0003] In the early days, the extract of Artemisia argyi was usually directly mixed with polyester melt and then spun. However, the functional components of the fiber skin or surface were lost in large quantities during washing and friction, which reduced the functional effect of Artemisia argyi in the fiber. Therefore, a technology has been disclosed that modifies nylon fiber with Artemisia argyi or peppermint extract and its preparation method. This technology first mixes Artemisia argyi or peppermint extract with nanoporous material and performs modification treatment. Since nanoporous material has a large specific surface area, the Artemisia argyi or peppermint extract is "encapsulated" in the pores of the porous material. Although the prepared Artemisia argyi or peppermint extract modified nylon fiber has uniform performance and plays a protective and load-bearing role, the release rate of Artemisia argyi extract is still relatively fast, and it can only play a certain role in delaying the release.

[0004] To this end, a method for preparing multifunctional regenerated cellulose fiber with antiviral, antibacterial and anti-mite properties has been disclosed in the literature. The method includes S1, preparation of a mixture of high-concentration Houttuynia cordata and Forsythia suspensa extracts; S2, preparation of microcapsule slurry of Houttuynia cordata and Artemisia argyi essential oil mixture; S3, preparation of multifunctional modified additives; S4, preparation of blended spinning solution; and S5, spinning and post-treatment. This invention uses ethanol to extract Houttuynia cordata and Forsythia suspensa, and freeze-drys to make them into dry powder. After grinding, they are formed into nanostructures, making it easier for the Houttuynia cordata and Forsythia suspensa components to be retained and distributed in the fiber. The resulting functional regenerated cellulose fiber has antiviral, antibacterial, and anti-mite properties. The microcapsule technology mentioned above is increasingly used in fibers, but some technical problems still exist. For example, the functionality of the fiber is limited in the early stages of use due to the encapsulation of microcapsules, such as antibacterial properties. The antibacterial material is released slowly due to the encapsulation of microcapsules. The fiber only exhibits antibacterial properties after a period of use. Therefore, the antibacterial performance of the prepared fiber is not obvious during fiber testing, which obviously cannot meet the current needs of the medical field.

[0005] Another publicly available technology proposes a method for preparing Artemisia argyi high-efficiency sustained-release microcapsule cellulose fiber to address the shortcomings of the aforementioned improved technology. This method includes the preparation of a forming fluid for Artemisia argyi high-efficiency sustained-release microcapsules, modification of the forming fluid, and spinning steps. This technology claims that the Artemisia argyi high-efficiency sustained-release microcapsule cellulose fiber prepared by this method has highly efficient antibacterial activity, exhibiting excellent antibacterial properties from the initial stage of fiber preparation. Within one week of fiber preparation, tests show antibacterial rates of ≥99.9% against Staphylococcus aureus, Escherichia coli, and Candida albicans. While it exhibits excellent antibacterial properties initially, it merely adds a sustained-release agent to the capsule shell component in existing microcapsule technology. Based on its instructions and examples, it cannot be concluded that "the Artemisia argyi high-efficiency sustained-release microcapsule cellulose fiber prepared by this method has highly efficient antibacterial activity and exhibits excellent antibacterial properties from the initial stage of fiber preparation," thus failing to achieve any improvement effect.

[0006] Therefore, it is necessary to innovate and improve the process methods and equipment for incorporating artemisia extract into fibers and maintaining a long functional lifespan. Summary of the Invention

[0007] (a) Technical problems to be solved

[0008] To address the shortcomings of existing technologies, this invention provides a nanofiber containing artemisia extract, along with its production method and equipment, which solves the problem in existing technologies where the volatilization of artemisia extract's efficacy does not meet usage requirements.

[0009] (II) Technical Solution

[0010] To achieve the above objectives, the present invention provides the following technical solution: a nanofiber containing Artemisia argyi extract, comprising a fiber body, wherein the fiber body consists of a core layer and a sheath layer covering the outer wall of the core layer, the core layer and the sheath layer being composite spun using a melt spinning device, the core layer consisting of polyester melt and drug-loaded porous microspheres, the drug-loaded porous microspheres consisting of porous microspheres with three-dimensional interconnected pores and a drug layer located inside the interconnected pores, the drug layer being composed of Artemisia argyi extract, a sustained-release agent, and a solvent, the sheath layer consisting of polyester melt and a pore-forming agent, the pore-forming agent inside the sheath layer being spun in the fiber body. After completion, the microspheres are washed with water to remove impurities, thus forming multiple sets of pores. The diameter of the drug-loaded porous microspheres is 5-20 μm, and the amount of drug-loaded porous microspheres added is 2-3% based on the weight of the polyester melt in the core layer. The sustained-release agent in the drug layer is selected from any one of polycaprolactone, polylactic acid, gelatin, hyaluronic acid, collagen, sodium alginate, and polylactic acid-glycolic acid copolymer. The solvent is purified water. The pore-forming agent is any one of sodium chloride particles and calcium chloride particles. The pore-forming agent is elongated and its length is greater than the thickness of the skin layer. The amount of pore-forming agent added is 8.5-9.7% based on the weight of the polyester melt in the skin layer.

[0011] A method for producing nanofibers containing Artemisia argyi extract, the method comprising the following steps:

[0012] S1. Prepare the drug layer. Pour pure water into the stirring device and start the stirring device. Add Artemisia argyi extract to the pure water. Control the stirring speed of the stirring device to 350-450 r / min when adding Artemisia argyi extract. After stirring for 10 min, add the sustained-release agent to the mixture. Control the stirring speed of the stirring device to 200-260 r / min when adding Artemisia argyi extract. Stir for 30 min. After stirring is completed, the drug layer mixture is obtained.

[0013] S2. Prepare drug-loaded porous microspheres. Take the raw material for forming porous microspheres and add it to the drug layer mixture prepared in S1. Stir at 400-660 r / min for 30 min. Then add the first organic solvent in sequence and use the phase separation method to obtain drug-loaded droplets. Transfer the drug-loaded droplets to the second organic solvent for solidification to form drug-loaded porous microspheres.

[0014] S3. Prepare the core layer polyester melt by melting and polymerizing high-shrinkage PET chips and drug-loaded porous microspheres at 255-260℃ to form the core layer polyester melt.

[0015] S4. Prepare the skin layer polyester melt by melting and polymerizing high-shrinkage PET chips and pore-forming agent at 250-260℃ to form the skin layer polyester melt.

[0016] S5. Melt spinning: Using melt spinning equipment, the core layer polyester melt and the sheath layer polyester melt are transported through a set of melt conveying channels. After being pressurized by a booster pump and mixed by a static mixer, they are sent into two spinning boxes and spun through a composite spinneret to form a composite nascent fiber with the sheath layer covering the outer wall of the core layer. The composite nascent fiber is cooled by ring blowing, oiled, and hot-drawn before being wound into a fiber semi-finished product.

[0017] S6. Washing: The semi-finished fiber obtained by melt spinning equipment is placed in a special washing machine. A washing agent is added to the washing machine, and the temperature is raised to 100°C to soak the semi-finished fiber. After shaking, the pore-forming agent in the skin layer is removed to form pores. After washing, the fiber is dehydrated and dried at low temperature to obtain nanofibers containing Artemisia argyi extract.

[0018] Preferably, the weight ratio of sustained-release agent, Artemisia argyi extract, and solvent in the drug layer mixture of S1 is 1:2:8-1:5:6.

[0019] Preferably, in S2, the weight ratio of the drug layer mixture, the porous microsphere raw material, and the first organic solvent is 0.5:2:10, and the weight ratio of the drug-loaded droplets to the second organic solvent in S2 is 2.5:10.

[0020] A production device for nanofibers containing Artemisia argyi extract is disclosed. The device employs the aforementioned production method and includes a stirring device, a melt spinning device, a washing device, a washing agent supply tank, a clean water tank, and two sets of recycling tanks. The washing device comprises an outer casing fixedly connected to the upper walls of four sets of first supports. A top cover is rotatably connected to the upper wall of the outer casing via a hinge. A drive assembly is provided between the top cover and the outer casing to drive the top cover to rotate and open along the hinge. The lower inner wall of the outer casing is fixed by four second supports. The container is connected to an inner box. A flange is provided on the outer wall of the inner box at the upper edge. The inner box is fixedly connected to the inner side wall of the outer box via the flange. A sealing structure is provided between the top cover and the flange of the inner box. Two sets of fixing plates are fixedly connected to the front and rear inner walls of the inner box. All four sets of fixing plates are close to the upper edge of the inner box. Sliding columns are fixedly connected between the four sets of fixing plates and the lower inner wall of the inner box. Sliding sleeves are slidably connected to the outer walls of the four sets of sliding columns. A platform is fixedly connected between the four sets of sliding sleeves. The side wall of the platform is connected to the upper... A linkage structure is provided between the inner sidewalls of the lid to drive the platform to rise and fall when the lid is opened and closed. An ultrasonic component is provided on the outer wall of the inner box to generate high-frequency oscillation to enhance the washing effect. Temperature control components are also provided on the lower wall and inner sidewalls of the inner box. From left to right, a suction pipe, a first liquid inlet pipe, and a second liquid inlet pipe are fixedly connected to the front wall of the outer box. The ends of the suction pipe, the first liquid inlet pipe, and the second liquid inlet pipe facing the front wall of the outer box all sequentially penetrate the front wall of the outer box, the front wall of the inner box, and communicate with the interior of the inner box. A vacuum pump is fixedly connected to the end of the suction pipe away from the outer box. The ends of the first liquid inlet pipe and the second liquid inlet pipe away from the outer box are respectively connected to the detergent supply tank and the clean water tank through two sets of water pumps. The lower wall of the outer box is fixedly connected to the first liquid return pipe and the second liquid return pipe from left to right. The ends of the first liquid return pipe and the second liquid return pipe facing the lower wall of the outer box pass through the lower wall of the outer box and the lower wall of the inner box in sequence and communicate with the interior of the inner box. The ends of the first liquid return pipe and the second liquid return pipe away from the lower wall of the outer box are respectively connected to two sets of recovery tanks through two sets of water pumps.

[0021] Preferably, the drive assembly includes two sets of first pivot pins, second pivot pins, and hydraulic cylinders. The two sets of first pivot pins are respectively fixedly connected to the left and right side walls of the outer casing and are close to the front wall of the outer casing. The two sets of second pivot pins are respectively fixedly connected to the left and right side walls of the upper cover and are respectively vertically opposite to the two sets of first pivot pins. The two sets of hydraulic cylinders are respectively rotatably connected between the two sets of vertically opposite first pivot pins and second pivot pins.

[0022] Preferably, the linkage structure includes two sets of hanging pins, a first connecting arm, and a second connecting arm. The two sets of hanging pins are fixedly connected to the left and right side walls of the platform, respectively. The two sets of first connecting arms are rotatably connected to the inner left and inner right walls of the upper cover through a set of rotating seats, respectively. The two sets of second connecting arms are rotatably connected to the outer walls of the hanging pins, and the ends of the two sets of second connecting arms away from the hanging pins are rotatably connected to the ends of the two sets of first connecting arms away from the rotating seats, respectively.

[0023] Preferably, the ultrasonic component includes multiple sets of ultrasonic transducers, which are respectively fixedly connected to the lower wall of the inner box and the left and right side walls of the inner box.

[0024] Preferably, the temperature control component includes two electric heating layers and multiple sets of temperature sensors. The multiple sets of temperature sensors are respectively fixedly connected to the lower wall of the inner box, and the temperature sensor detection part extends into the inner box after penetrating the lower wall of the inner box. The two electric heating layers are respectively fixedly connected to the inner front wall and inner rear wall of the inner box.

[0025] Preferably, the sealing structure is a sealing layer, and a sealing groove is provided on the side of the upper cover and the inner box flange that are opposite each other. The sealing layer is provided on the inner side wall of the sealing groove, and when the upper cover is closed, the lower wall of the sealing layer abuts against the upper surface of the inner box flange.

[0026] (III) Beneficial Effects

[0027] This invention provides nanofibers containing Artemisia argyi extract, as well as a method and equipment for their production. It offers the following advantages:

[0028] 1. Compared with existing technologies, this nanofiber containing Artemisia argyi extract and its production method involve mixing Artemisia argyi extract with a slow-release agent and encapsulating it into porous microspheres to form drug-loaded porous microspheres. The drug-loaded porous microspheres are then blended and melted with a core layer polyester melt and spun using melt spinning equipment to form the core layer. Combined with a skin layer polyester melt containing a pore-forming agent, they are spun together to form a composite fiber semi-finished product. After washing to remove the pore-forming agent, multiple interconnected micropores are formed on the skin surface. The Artemisia argyi extract in the drug layer of the drug-loaded porous microspheres can be slowly released through the slow-release agent and transferred outward through multiple sets of micropores. After being made into fabric, the Artemisia argyi extract does not come into direct contact with the skin, but can be carried by the porous microspheres and slowly released through the micropores. It is also resistant to washing and friction, greatly improving its long-term effectiveness.

[0029] 2. Compared with existing technologies, this nanofiber production equipment containing Artemisia argyi extract, through the connection between the inner tank and the clean water tank, the washing agent supply tank, and the recycling tank, can sequentially complete the washing agent cleaning to remove pore-forming agents and the clean water cleaning after the fiber semi-finished product is placed on the platform. In addition, with the help of the electric heating layer, the low-temperature drying can be completed after the clean water cleaning. During the cleaning process, high-frequency ultrasonic waves are emitted by multiple sets of ultrasonic transducers to oscillate, thereby improving the cleaning efficiency. The top cover is opened and closed by the extension shaft of the hydraulic cylinder. During the opening and closing process, the platform is raised and lowered by the linkage structure, which facilitates the removal of the product. Attached Figure Description

[0030] Figure 1 This is a schematic diagram of the overall structure of the water washing equipment of the present invention;

[0031] Figure 2 This is a partial sectional view of the internal structure of the washing equipment of the present invention.

[0032] Figure 3 For the present invention Figure 2 A magnified view of a section at point A in the middle;

[0033] Figure 4 For the present invention Figure 2 A magnified view of a section at point B in the middle;

[0034] Figure 5 For the present invention Figure 2 A magnified view of a section at point C;

[0035] Figure 6 This is a top view schematic diagram of the platform structure of the present invention;

[0036] Figure 7 This is a schematic diagram of a partial cross-section of the fiber body structure of the present invention.

[0037] The components are as follows: 1. First support; 2. Outer casing; 3. Top cover; 4. First pivot pin; 5. Second pivot pin; 6. Hydraulic cylinder; 7. First inlet pipe; 8. Second inlet pipe; 9. First return pipe; 10. Second return pipe; 11. Vacuum pipe; 12. Vacuum pump; 13. Second support; 14. Inner casing; 15. Ultrasonic transducer; 16. Fixing plate; 17. Sliding column; 18. Sliding sleeve; 19. Platform; 20. First connecting arm; 21. Second connecting arm; 22. Hanging pin; 23. Sealing layer; 24. Temperature sensor; 25. Electric heating layer; 26. Core layer; 27. Skin layer; 28. Air vent. Detailed Implementation

[0038] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0039] Example:

[0040] like Figure 7 As shown, this embodiment of the invention provides a nanofiber containing Artemisia argyi extract, comprising a fiber body, which consists of a core layer 26 and a sheath layer 27 covering the outer wall of the core layer 26. The core layer 26 and the sheath layer 27 are composite spun using a melt spinning device. The core layer 26 consists of polyester melt and drug-loaded porous microspheres. The drug-loaded porous microspheres consist of porous microspheres with three-dimensional interconnected pores inside and a drug layer located inside the interconnected pores. The drug layer is composed of Artemisia argyi extract, a sustained-release agent, and a solvent. The sheath layer 27 consists of polyester melt and a pore-forming agent. The pore-forming agent inside the sheath layer 27 is removed by washing after the fiber body is spun, thereby forming multiple sets of pores 28. The diameter of the drug-loaded porous microspheres is 15 μm, and the amount of drug-loaded porous microspheres added is 2% based on the weight of the polyester melt in the core layer 26. The sustained-release agent in the drug layer is sodium alginate, and the solvent is purified water. The pore-forming agent is sodium chloride particles. The pore-forming agent is elongated and its length is greater than the thickness of the skin layer 27. The amount of pore-forming agent added is 8.5%, based on the weight of the polyester melt in the skin layer 27. Artemisia argyi extract is mixed with a slow-release agent and encapsulated into porous microspheres to form drug-loaded porous microspheres. The drug-loaded porous microspheres are then blended and melted with the polyester melt of the core layer 26 and spun through a melt spinning device to form the core layer 26. Together with the polyester melt of the skin layer 27 containing the pore-forming agent, they are spun together to form a composite fiber semi-finished product. After washing to remove the pore-forming agent, multiple interconnected micropores 28 are formed on the surface of the skin layer. The Artemisia argyi extract in the drug layer of the drug-loaded porous microspheres can be slowly released by the slow-release agent and transferred outward through multiple sets of micropores 28. After being made into fabric, the Artemisia argyi extract does not come into direct contact with the skin, but can be carried by the porous microspheres. With the slow release of the micropores 28, it is not afraid of washing and friction, which greatly improves its long-term use effect.

[0041] A method for producing nanofibers containing Artemisia argyi extract, the method comprising the following steps:

[0042] S1. Prepare the drug layer. Pour pure water into the stirring device and start the stirring device. Add Artemisia argyi extract to the pure water. Control the stirring speed of the stirring device to 400 r / min when adding Artemisia argyi extract. After stirring for 10 min, add the sustained-release agent to the mixture. Control the stirring speed of the stirring device to 240 r / min when adding Artemisia argyi extract. Stir for 30 min. After stirring is completed, the drug layer mixture is obtained. The weight ratio of sustained-release agent, Artemisia argyi extract and solvent in the drug layer mixture is 1:2:8.

[0043] S2. Preparation of drug-loaded porous microspheres: The raw material for forming porous microspheres is added to the drug layer mixture prepared in S1. After stirring at 500 r / min for 30 min, the first organic solvent is added sequentially, and drug-loaded droplets are obtained by phase separation. The drug-loaded droplets are transferred to the second organic solvent for solidification to form drug-loaded porous microspheres. The weight ratio of drug layer mixture, raw material for forming porous microspheres to the first organic solvent is 0.5:2:10, and the weight ratio of drug-loaded droplets to the second organic solvent is 2.5:10. There are many published documents on the drug loading technology of porous microspheres, which will not be elaborated here.

[0044] S3. Prepare core layer 26 polyester melt. Melt polymerize high shrinkage PET chips and drug-loaded porous microspheres at 255-260℃ to form core layer 26 polyester melt. Using a common static mixer, the drug-loaded porous microspheres can be uniformly dispersed inside the core layer 26 polyester melt.

[0045] S4. Prepare the polyester melt for skin layer 27. Melt and polymerize high-shrinkage PET chips and pore-forming agent at 250-260℃ to form polyester melt for skin layer 27. The pore-forming agent is dispersed inside the polyester melt for skin layer 27. Because the length of the pore-forming agent strip is greater than the thickness of skin layer 27, some of the pore-forming agent is washed away by water, which makes the inner wall of skin layer 27 have pores 28 that are interconnected inside and outside.

[0046] S5. Melt spinning: Melt spinning equipment is used to transport the core layer 26 polyester melt and the sheath layer 27 polyester melt through a set of melt conveying channels. After being pressurized by a booster pump and mixed by a static mixer, they are sent into two spinning boxes and spun through a composite spinneret to form a composite nascent fiber with the sheath layer 27 covering the outer wall of the core layer 26. The composite nascent fiber is cooled by ring blowing, oiled, and hot-drawn before being wound into a fiber semi-finished product. Melt spinning equipment is currently a very mature technology.

[0047] S6. Washing: The semi-finished fiber obtained by melt spinning equipment is placed in a special washing machine. Washing agent is added to the washing machine, and the temperature is raised to 100°C to soak the semi-finished fiber. After shaking, the pore-forming agent in the skin layer 27 is removed, forming pores 28. After washing, the fiber is dehydrated and dried at low temperature to obtain nanofibers containing Artemisia argyi extract. The amount of pore-forming agent added is 8.5%. Based on the weight of polyester melt in the skin layer 27, after removing the pore-forming agent, multiple pores 28 are formed on the surface of the skin layer 27. The specific usage method of the washing equipment is explained in detail below.

[0048] like Figures 1 to 6 This invention provides a production device for nanofibers containing Artemisia argyi extract. The production device employs the above production method and includes a stirring device, a melt spinning device, a washing device, a washing agent supply tank, a clean water tank, and two sets of recycling tanks. The washing device includes an outer box 2 fixedly connected to the upper wall of four sets of first supports 1. An upper cover 3 is rotatably connected to the upper wall of the outer box 2 via a hinge. A driving assembly for driving the upper cover 3 to rotate and open along the hinge is provided between the upper cover 3 and the outer box 2. The driving assembly includes two sets of first pivot pins 4, second pivot pins 5, and a hydraulic cylinder 6. The two sets of first pivot pins 4... Two sets of second pivot pins 5 are fixedly connected to the left and right side walls of the outer box 2 and are close to the front wall of the outer box 2. Two sets of second pivot pins 5 are fixedly connected to the left and right side walls of the upper cover 3 and are respectively opposite to the two sets of first pivot pins 4. Two sets of hydraulic cylinders 6 are rotatably connected between the two sets of first pivot pins 4 and second pivot pins 5 that are opposite to each other. The hydraulic cylinders 6 are driven by a common hydraulic controller and driver. When the extension shaft of the hydraulic cylinder 6 extends, it drives the upper cover 3 to rotate and open along the hinge, so as to facilitate the loading and unloading of products. When the extension shaft of the hydraulic cylinder 6 retracts, it drives the upper cover 3 to rotate and close along the hinge, so as to facilitate the washing operation.

[0049] From left to right, the front wall of the outer casing 2 is fixedly connected to a suction pipe 11, a first liquid inlet pipe 7, and a second liquid inlet pipe 8. The ends of the suction pipe 11, the first liquid inlet pipe 7, and the second liquid inlet pipe 8 facing the front wall of the outer casing 2 all pass through the front wall of the outer casing 2 and the front wall of the inner casing 14, respectively, and communicate with the interior of the inner casing 14. The ends of the first liquid inlet pipe 7 and the second liquid inlet pipe 8 away from the outer casing 2 are respectively connected to a detergent supply tank and a clean water tank via two sets of water pumps. From left to right, the lower wall of the outer casing 2 is fixedly connected to a first return pipe 9 and a second return pipe 10. The ends of the first return pipe 9 and the second return pipe 10 facing the lower wall of the outer casing 2... The ends of the first return pipe 9 and the second return pipe 10 pass through the lower wall of the outer box 2 and the lower wall of the inner box 14 in sequence and are connected to the interior of the inner box 14. The ends of the first return pipe 9 and the second return pipe 10 away from the lower wall of the outer box 2 are respectively connected to the two sets of recycling tanks through two sets of water pumps. During water washing, the washing agent enters the inner box 14 through the first inlet pipe 7. The washing agent dissolves the pore-forming agent in the skin layer 27 to form pores 28. After water washing is completed, the washing agent in the inner box 14 returns to the recycling tank through the first return pipe 9. Then, clean water is introduced through the second inlet pipe 8 to rinse the product. The rinsed clean water returns to the recycling tank through the second return pipe 10.

[0050] The inner box 14 is fixedly connected to the lower inner wall of the outer box 2 via the second brackets 13 around the perimeter. The outer wall of the inner box 14 and the upper edge of the inlet are provided with a flange. The inner box 14 is fixedly connected to the inner wall of the outer box 2 via the flange. A sealing structure is provided between the upper cover 3 and the flange of the inner box 14. The sealing structure is a sealing layer 23. A sealing groove is provided on the side of the upper cover 3 and the flange of the inner box 14 that are opposite each other. The sealing layer 23 is provided on the inner wall of the sealing groove. A vacuum pump 12 is fixedly connected to the end of the exhaust pipe 11 away from the outer box 2. When the top cover 3 is closed, the lower wall of the sealing layer 23 is pressed against the upper surface of the inner box 14. During the water washing operation, in order to avoid the odor generated during the high temperature water washing process from affecting the workshop environment, the sealing layer 23 seals the top cover 3 and the inner box 14. At the same time, before opening the top cover 3, the vacuum pump 12 is used to extract the gas inside the inner box 14 along the air extraction pipe 11. Before the air extraction, the oil cylinder 6 can be used to rotate the top cover 3 to open a gap, so as to avoid the formation of negative pressure inside after the air extraction, which would prevent the top cover 3 from being unable to be opened.

[0051] Two sets of fixing plates 16 are fixedly connected to the inner front wall and inner rear wall of the inner box 14. All four sets of fixing plates 16 are close to the upper edge of the inner box 14. Sliding columns 17 are fixedly connected between the four sets of fixing plates 16 and the lower inner wall of the inner box 14. Sliding sleeves 18 are slidably connected to the outer walls of the four sets of sliding columns 17. A platform 19 is fixedly connected between the four sets of sliding sleeves 18. A linkage structure is provided between the side wall of the platform 19 and the inner wall of the upper cover 3 for raising and lowering the platform 19 when the upper cover 3 is opened and closed. The linkage structure includes two sets of hook pins 22, a first connecting arm 20, and a second connecting arm 21. The two sets of hook pins 22 are respectively... Fixedly connected to the left and right side walls of the platform 19, two sets of first connecting arms 20 are rotatably connected to the inner left and inner right walls of the upper cover 3 through a set of rotating seats, and two sets of second connecting arms 21 are rotatably connected to the outer wall of the hanging pin 22. The ends of the two sets of second connecting arms 21 away from the hanging pin 22 are rotatably connected to the ends of the two sets of first connecting arms 20 away from the rotating seats. When the cylinder 6 drives the upper cover 3 to rotate open and close, the platform 19 is driven to rise and fall along the sliding column 17 through the first connecting arms 20, the second connecting arms 21 and the hanging pin 22, thereby facilitating the placement and retrieval of products.

[0052] The outer wall of the inner box 14 is provided with an ultrasonic component for generating high-frequency oscillation to enhance the washing effect. The ultrasonic component includes multiple sets of ultrasonic transducers 15, which are fixedly connected to the lower wall of the inner box 14 and the left and right side walls of the inner box 14 respectively. During the washing and rinsing process, high-frequency ultrasonic waves are emitted through the ultrasonic component, which improves the washing and rinsing efficiency and shortens the processing time.

[0053] The lower wall and inner side wall of the inner box 14 are also equipped with a temperature control component for controlling the temperature. The temperature control component includes two electric heating layers 25 and multiple temperature sensors 24. The multiple temperature sensors 24 are fixedly connected to the lower wall of the inner box 14, and the detection part of the temperature sensor 24 penetrates through the lower wall of the inner box 14 and extends into the interior of the inner box 14. The two electric heating layers 25 are fixedly connected to the inner front wall and inner rear wall of the inner box 14. The electric heating layers 25 are used to heat the washing agent and also to heat the fiber body at low temperature after rinsing and draining the clean water.

[0054] Working principle: Polyester melt of sheath 27 and core layer 26 is produced by stirring equipment, and composite fiber semi-finished product is produced by melt spinning equipment. The composite fiber semi-finished product is washed and dried by washing equipment to form fiber body.

[0055] When the washing equipment is in use, the hydraulic cylinder 6 is driven by a commonly available hydraulic controller and driver. When the extension shaft of the hydraulic cylinder 6 extends, it drives the upper cover 3 to rotate and open along the hinge, thus facilitating the loading and unloading of products. When the extension shaft of the hydraulic cylinder 6 retracts, it drives the upper cover 3 to rotate and close along the hinge, thus facilitating the washing operation. During washing, the washing agent enters the inner tank 14 through the first inlet pipe 7. The washing agent dissolves the pore-forming agent in the skin layer 27, forming pores 28. After washing, the washing agent in the inner tank 14 returns to the recovery tank through the first return pipe 9, and then clean water is introduced through the second inlet pipe 8 to rinse the product. The rinsed clean water returns to the recovery tank through the second return pipe 10. During the washing and rinsing process, high-frequency ultrasonic waves are emitted by the ultrasonic component, which improves the washing and rinsing efficiency and shortens the processing time. The two electric heating layers 25 are respectively fixed. The electric heating layer 25 is fixedly connected to the front and rear inner walls of the inner box 14. It is used to heat the washing agent and also to heat the fiber body at low temperature after rinsing and draining the clean water. During the washing operation, in order to avoid the odor generated during the high-temperature washing process from affecting the workshop environment, the upper cover 3 and the inner box 14 are sealed by the sealing layer 23. At the same time, before opening the upper cover 3, the vacuum pump 12 is used to extract the gas inside the inner box 14 along the air extraction pipe 11. Before the air extraction, the upper cover 3 can be rotated by the oil cylinder 6 to open a gap, so as to avoid the formation of negative pressure inside after the air extraction, which would prevent the upper cover 3 from being unable to be opened. When the oil cylinder 6 drives the upper cover 3 to rotate to open and close, the first connecting arm 20, the second connecting arm 21 and the hanging pin 22 drive the platform 19 to rise and fall along the sliding column 17, thereby facilitating the loading and unloading of products.

[0056] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A nanofiber comprising a mugwort extract, comprising a fiber body, characterized by: The fiber body is composed of a core layer (26) and a skin layer (27) wrapped outside the core layer (26), the core layer (26) and the skin layer (27) are made by melt spinning equipment composite spinning, the core layer (26) is composed of polyester melt and drug-loaded porous microspheres, the drug-loaded porous microspheres are composed of a pore-forming microsphere with a three-dimensional interconnected pore inside and a drug layer located inside the interconnected pore, the drug layer is mixed by artemisia extract, sustained-release agent and solvent, the skin layer (27) is composed of polyester melt and porogen, the porogen inside the skin layer (27) is removed by water washing machine after the spinning of the fiber body is completed to form a plurality of groups of pores (28); the diameter of the drug-loaded porous microspheres is 5-20μm, the amount of the drug-loaded porous microspheres added is 2-3%, based on the weight of the polyester melt in the core layer (26); the sustained-release agent in the drug layer is selected from any one of polycaprolactone, polylactic acid, gelatin, hyaluronic acid, collagen, sodium alginate and poly(lactic-co-glycolic acid); the solvent is pure water; the porogen is any one of sodium chloride particles and calcium chloride particles, the porogen is in the shape of a long strip and the length of the long strip is greater than the thickness of the skin layer (27), the amount of the porogen added is 8.5-9.7%, based on the weight of the polyester melt in the skin layer (27); The production method of the artemisia extract-containing nanofiber comprises the following steps: S1, preparing a drug layer, pure water is poured into a stirring device, the stirring device is started, artemisia extract is taken and added into the pure water, the stirring speed of the stirring device when the artemisia extract is added is controlled to be 350-450r / min, after stirring for 10min, a sustained-release agent is taken and added into the mixed solution, the stirring speed of the stirring device when the artemisia extract is added is controlled to be 200-260r / min, stirring is performed for 30min, and after the stirring is completed, a drug layer mixed solution is obtained; S2, preparing drug-loaded porous microspheres, pore-forming microsphere raw materials are taken and added into the drug layer mixed solution prepared in S1, stirring is performed at 400-660r / min for 30min, a first organic solvent is added in sequence to obtain drug-loaded droplets by phase separation, the drug-loaded droplets are transferred into a second organic solvent for solidification to form drug-loaded porous microspheres; S3, preparing core layer (26) polyester melt, high shrinkage PET chips and drug-loaded porous microspheres are melt polymerized at 255-260℃ to form core layer (26) polyester melt; S4, preparing skin layer (27) polyester melt, high shrinkage PET chips and porogen are melt polymerized at 250-260℃ to form skin layer (27) polyester melt; S5, melt spinning, melt spinning equipment is adopted, the core layer (26) polyester melt and the skin layer (27) polyester melt are respectively conveyed by a group of melt conveying channels, are pressurized by a booster pump and mixed by a static mixer, and are then sent into two spinning box bodies, and the composite primary fibers with the skin layer (27) wrapped outside the core layer (26) are formed by a composite spinneret plate, and the composite primary fibers are cooled by a ring blowing machine, are oiled, are hot drawn, and are then wound into fiber semi-products. S6, the fiber semi-finished product obtained by the melt spinning device is put into a special washing machine, a washing agent is added into the washing machine, the fiber semi-finished product is soaked at a temperature of 100 DEG C, and the porogen in the skin layer (27) is removed after oscillation to form pores (28), after the washing is completed, dehydration and low-temperature drying are performed to obtain the artemisia extract-containing nanofiber.

2. The method for producing nanofibers containing Artemisia argyi extract according to claim 1, characterized in that: The weight ratio of the sustained-release agent, the artemisia extract and the solvent in the drug layer mixed solution of S1 is 1:2:8 or 1:5:

6.

3. The method for producing nanofibers containing Artemisia argyi extract according to claim 2, characterized in that: The weight ratio of the drug layer mixed solution, the pore-forming microsphere raw material and the first organic solvent in S2 is 0.5:2:10, and the weight ratio of the drug-loaded liquid droplet and the second organic solvent in S2 is 2.5:

10.

4. The apparatus for producing nanofiber containing artemisia extract according to claim 1, characterized in that: The production equipment adopts the production method of claims 2-3, and comprises stirring equipment, melt spinning equipment, water washing equipment, water washing agent providing tank, clean water tank, and two groups of recovery tanks; the water washing equipment comprises an outer tank (2) fixedly connected to the upper wall of four first supports (1), an upper cover (3) hingedly connected to the upper wall of the outer tank (2), a driving assembly arranged between the upper cover (3) and the outer tank (2) and used to drive the upper cover (3) to rotate along the hinge to open, an inner tank (14) fixedly connected to the lower inner wall of the outer tank (2) through four second supports (13), a flange arranged on the outer wall of the inner tank (14) and at the upper edge position, the inner tank (14) fixedly connected to the inner side wall of the outer tank (2) through the flange, a sealing structure arranged between the upper cover (3) and the flange of the inner tank (14), two groups of fixed plates (16) fixedly connected to the front inner wall and the rear inner wall of the inner tank (14), four groups of the fixed plates (16) close to the upper edge of the inner tank (14), a sliding column (17) fixedly connected between each of the four groups of the fixed plates (16) and the lower inner wall of the inner tank (14), a sliding sleeve (18) slidingly connected to the outer wall of each of the four groups of the sliding columns (17), a loading platform (19) fixedly connected between the four groups of the sliding sleeves (18), a linkage structure arranged between the side wall of the loading platform (19) and the inner side wall of the upper cover (3) and used to drive the loading platform (19) to ascend or descend when the upper cover (3) is opened or closed, an ultrasonic assembly arranged on the outer wall of the inner tank (14) and used to generate ultrasonic oscillation to increase the water washing effect, a temperature control assembly arranged on the lower wall and the inner side wall of the inner tank (14) and used to control the temperature, an air exhaust pipe (11), a first liquid inlet pipe (7), and a second liquid inlet pipe (8) fixedly connected to the front wall of the outer tank (2) from left to right, one ends of the air exhaust pipe (11), the first liquid inlet pipe (7), and the second liquid inlet pipe (8) towards the front wall of the outer tank (2) penetrating the front wall of the outer tank (2), the front wall of the inner tank (14), and the inner part of the inner tank (14) in sequence, a vacuum pump (12) fixedly connected to the end of the air exhaust pipe (11) away from the outer tank (2), the first liquid inlet pipe (7) and the second liquid inlet pipe (8) connected to the water washing agent providing tank and the clean water tank through two groups of water pumps at the ends thereof away from the outer tank (2), a first liquid return pipe (9) and a second liquid return pipe (10) fixedly connected to the lower wall of the outer tank (2) from left to right, one ends of the first liquid return pipe (9) and the second liquid return pipe (10) towards the lower wall of the outer tank (2) penetrating the lower wall of the outer tank (2), the lower wall of the inner tank (14), and the inner part of the inner tank (14) in sequence, and the ends of the first liquid return pipe (9) and the second liquid return pipe (10) away from the lower wall of the outer tank (2) connected to the two groups of recovery tanks through two groups of water pumps.

5. The apparatus for producing nanofiber containing artemisia extract according to claim 4, characterized in that: The driving assembly comprises two groups of first rotating pins (4), second rotating pins (5) and oil cylinders (6), the two groups of first rotating pins (4) are fixedly connected to the left and right side walls of the outer box (2) and close to the front wall of the outer box (2), the two groups of second rotating pins (5) are fixedly connected to the left and right side walls of the upper cover (3) and are opposite to the two groups of first rotating pins (4) in the up-down direction, and the two groups of oil cylinders (6) are rotatably connected between the two groups of first rotating pins (4) and the second rotating pins (5) in the up-down direction.

6. The apparatus for producing nanofiber containing artemisia extract according to claim 4, characterized in that: The linkage structure comprises two groups of hanging pins (22), first connecting arms (20) and second connecting arms (21), the two groups of hanging pins (22) are fixedly connected to the left and right side walls of the object table (19), the two groups of first connecting arms (20) are rotatably connected to the inner left wall and the inner right wall of the upper cover (3) through a group of rotating seats, the two groups of second connecting arms (21) are rotatably connected to the outer walls of the hanging pins (22), and the ends of the two groups of second connecting arms (21) away from the hanging pins (22) are rotatably connected to the ends of the two groups of first connecting arms (20) away from the rotating seats.

7. The apparatus according to claim 4, wherein the apparatus is characterized by comprising: a nanofiber production device containing the extract of artemisia. The ultrasonic wave assembly comprises a plurality of groups of ultrasonic wave transducers (15), and the plurality of groups of ultrasonic wave transducers (15) are fixedly connected to the lower wall of the inner box (14) and the left and right side walls of the inner box (14).

8. The apparatus according to claim 4, wherein the apparatus is characterized by comprising: a nanofiber production device containing the extract of artemisia. The temperature control assembly comprises two electric heating layers (25) and a plurality of groups of temperature sensors (24), the plurality of groups of temperature sensors (24) are fixedly connected to the lower wall of the inner box (14), and the detection parts of the temperature sensors (24) extend into the inner box (14) after penetrating through the lower wall of the inner box (14), and the two electric heating layers (25) are fixedly connected to the inner front wall and the inner rear wall of the inner box (14).

9. The apparatus for producing nanofiber containing artemisia extract according to claim 4, characterized in that: The sealing structure is a sealing layer (23), the upper cover (3) and the inner box (14) are provided with a sealing groove on the side opposite to the folded edge in the up-down direction, the sealing layer (23) is arranged on the inner side wall of the sealing groove, and the lower wall of the sealing layer (23) is tightly abutted against the upper surface of the folded edge of the inner box (14) when the upper cover (3) is closed.

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