Pressure injury-free chromatograph and method of operating the same

Abstract

This invention discloses a pressure-damage-free chromatograph and its operating method, comprising a chromatograph body and a line source block, and further including a pressure-free storage component and / or a pressure-free sealing component. The pressure-free storage component provides protection through storage and positioning. When in use, the line source block extends out of the storage frame, exposing its wiring terminals to ensure normal wiring operation. When not in use, it is stored back in the storage frame to prevent accidental contact or compression. The pressure-free sealing component provides protection through sealing. The line source block is placed in a protective frame, and a protective cover seals the wiring terminals of the line source block, thereby preventing accidental contact or compression damage. The arrangement of these two components has a positive impact on the normal use of the chromatograph and meets practical usage requirements. The pressure-damage-free chromatograph and its operating method provided by this invention can significantly improve the safety of the chromatograph and extend its service life.

Description

Technical Field

[0001] This invention relates to the field of chromatography technology, specifically to a pressure-damage-free chromatograph and its operating method. Background Technology

[0002] Chromatography is one of the "four major spectroscopic instruments" (spectroscopy, chromatography, mass spectrometry, and wavelength dispersive spectroscopy), and it is an analytical separation instrument. Liquid chromatography (LC) is at the forefront of this field, with a wide range of applications. It can efficiently, rapidly, and accurately separate mixtures in a sample into single components and determine their concentration within the mixture. Major application areas include biomedicine, proteomics, food safety, environmental protection, and in vitro medical diagnostics. Microfluidic liquid chromatographs, in particular, consist of a sampling system (including injectors, syringes, and inlets); a mobile phase system (including solvent bottles, pumps, mixers, and pressure reducers); detectors (including UV-Vis detectors, fluorescence detectors, and electrochemical detectors); and other auxiliary components such as temperature control systems, automated injection systems, and column ovens. With numerous components and modules, and a precisely interconnected structure, a pressure-free device is needed to ensure the normal operation and testing of the instrument.

[0003] Chinese patent document CN212540271U, published on 20210212, discloses an easy-to-install gas chromatograph. It addresses the problems of existing chromatographs being heavy and having a delicate internal structure, requiring careful handling during transport. Furthermore, the outer casing lacks sufficient leverage points, making it easy for transporters to accidentally touch the instrument panel and buttons, causing damage. Additionally, it addresses the common problem of excessive force during installation, often resulting in damage to the instrument's bottom. The invention utilizes a flexible assembly structure to add a convenient mounting frame to the traditional chromatograph, facilitating easy transport and installation. The detachable base and mounting bracket allow for easy relocation of the chromatograph, preventing pressure damage from sudden contact with the support surface during installation. The retractable handle eliminates the safety hazard caused by protruding handles.

[0004] The structure designed for the chromatograph in the above scheme can effectively avoid pressure damage during installation and placement. However, the line source block on the chromatograph is exposed on the outside, making it susceptible to collision and squeezing damage during handling or use. There is no corresponding storage structure or protective structure to protect it, which greatly threatens the normal use of the chromatograph and cannot meet the actual use requirements. Further improvement and optimization are needed.

[0005] Therefore, this invention proposes a pressure-damage-free chromatograph and its operating method to solve the above problems. Summary of the Invention

[0006] The purpose of this invention is to provide a pressure-damage-free chromatograph and its operating method to solve the problems mentioned in the background art.

[0007] To achieve the above objectives, the present invention provides the following technical solution:

[0008] The first aspect of the present invention is a pressure-damage-free chromatograph, comprising a chromatograph body and a line source block, and further comprising a pressure-free storage component and / or a pressure-free sealing component.

[0009] The pressure-free storage component includes a storage frame, which is hollow and open at one end. The closed end of the storage frame is connected to the side wall of the chromatograph body. The line source block is movably embedded in the storage frame. The closed end of the storage frame is provided with a first line outlet hole, which is connected to the side wall of the chromatograph body.

[0010] The pressure-free sealing assembly includes a protective frame, which is hollow and open at one end. The closed end of the protective frame is connected to the side wall of the chromatograph body. The line source block is movably embedded in the protective frame. A protective cover is detachably connected to the open end of the protective frame for sealing the line source block. A second line outlet hole is provided on the closed end of the protective frame, and the second line outlet hole is connected to the side wall of the chromatograph body.

[0011] In some embodiments of the present invention, the chromatograph is selected from either a gas chromatograph or a liquid chromatograph; preferably, the chromatograph is a liquid chromatograph; more preferably, the chromatograph is a microfluidic liquid chromatograph.

[0012] In some embodiments of the present invention, at least one extension body is provided on at least one side wall of the storage frame, and a groove is provided on the inner side wall of the extension body. At least one slider is provided on at least one side wall of the line source block, and the slider and the groove are matched one-to-one so that the slider slides and engages in the corresponding groove. The top surface of the extension body is provided with a groove, and the groove is provided with a first groove segment and a second groove segment in sequence along the direction close to the line source block. The groove penetrates the extension body and is used to accommodate the movable block and the positioning strip.

[0013] In some embodiments of the present invention, a movable block is provided in the first groove segment, and a positioning strip is provided on the movable block. The first groove matches the movable block, and the second groove matches the positioning strip. One end of the positioning strip is connected to the movable block, and the other end of the positioning strip passes through the second groove segment and extends out of the extension body. A return spring is sleeved on the positioning strip. One end of the return spring is connected to the movable block, and the other end of the return spring is connected to the groove wall of the first groove segment. This is used to movably position the movable block and the positioning strip in the groove by elastic force. The movable block is also provided with a pull buckle, which is located on the end face of the movable block away from the positioning strip, and is used to pull the movable block.

[0014] In some embodiments of the present invention, the groove width of the first groove segment along the axial direction perpendicular to the first groove segment is greater than the groove width of the second groove segment along the axial direction perpendicular to the first groove segment.

[0015] In some embodiments of the present invention, the slider is divided into a first slider segment and a second slider segment. The first slider segment and the second slider segment are arranged sequentially along the direction away from the chromatograph body, and the sidewall of the first slider segment is recessed inward. The sidewall of the first slider segment is provided with a first positioning slot. The first positioning slot matches the position of the second groove segment so that the positioning strip extends to the first positioning slot. The sidewall of the second slider segment is also provided with a second positioning slot. The second positioning slot is arranged away from the chromatograph body relative to the first positioning slot. The first positioning slot and the second positioning slot are used to insert the positioning strip to achieve positioning. The second positioning slot is connected to a movable slot. The movable slot is provided with a plurality of protruding first movable buffer blocks on both sides of the slot body along the direction away from the chromatograph body. The slider corresponding to the first movable buffer block is provided with a placement slot. The placement slot corresponds to the first movable buffer block one by one. The placement slot is provided with a first buffer spring. One end of the first buffer spring is connected to the slot wall of the placement slot, and the other end of the first buffer spring is connected to the first movable buffer block; for buffering elastic force.

[0016] In some embodiments of the present invention, the positioning strip is detachably and movablely engaged with the first positioning slot and the second positioning slot, respectively, for positioning when the wire source block extends and retracts.

[0017] In some embodiments of the present invention, an auxiliary inclined surface is provided at the end of the first movable buffer block away from the first buffer spring. The auxiliary inclined surface extends into a placement groove, and the cross-section of the auxiliary inclined surface gradually decreases in the direction away from the first buffer spring. It is used to contact the positioning clip to squeeze the first movable buffer block and the first buffer spring to realize the elastic buffer during the retraction process of the line source block.

[0018] In some embodiments of the present invention, the first positioning slot and the second positioning slot have the same shape, and the shape of the first positioning slot and the second positioning slot is selected from one of trapezoid, rectangle, square, triangle, circle and polygon; more preferably, the shape of the first positioning slot and the second positioning slot is trapezoidal; most preferably, the longitudinal section of the trapezoid gradually decreases along the direction close to the chromatograph body.

[0019] In some embodiments of the present invention, the number of placement slots is at least 6; more preferably, the number of placement slots is 6; most preferably, the number of placement slots is the same on opposite walls of the movable slot, the positions of the placement slots are opposite, and the interval between adjacent placement slots on the same side wall of the movable slot is equal.

[0020] In some embodiments of the present invention, at least one limiting groove is provided on at least one outer side wall of the protective frame, and a second movable buffer block is provided in the limiting groove. A second buffer spring is provided at both ends of the second movable buffer block. One end of the second buffer spring is connected to the second movable buffer block, and the other end of the second buffer spring is connected to the groove wall in the limiting groove. A connecting plate is connected to the top surface of the second movable buffer block. The connecting plate extends out of the limiting groove, and the end of the connecting plate away from the second movable buffer block is connected to the mounting frame. The second buffer spring enables the mounting frame to have a good elastic buffering effect.

[0021] In some embodiments of the present invention, the protective cover is hollow and open at one end, and a plurality of second magnetic sheets are provided on the end face of the open end of the protective cover. A handle is also provided on the closed end of the protective cover for pulling the protective cover to separate the protective cover from the frame groove.

[0022] In some embodiments of the present invention, the limiting movable groove is disposed on the outer side wall of the protective frame near the opening end; the short side width of the opening of the limiting movable groove is smaller than the short side width of the groove opening; the second movable buffer block is located at the center of the limiting movable groove; the long side length of the second movable buffer block is smaller than the long side length of the groove opening; the short side width of the second movable buffer block is not greater than the short side width of the groove opening but greater than the short side width of the opening of the limiting movable groove, so that the second movable buffer block can be engaged in the limiting movable groove. It can only move back and forth in a straight line within the limiting groove; each of the four outer side walls of the protective frame is provided with a limiting groove, and each outer side wall of the protective frame is provided with at least one limiting groove; preferably, each outer side wall of the protective frame is provided with one limiting groove; the mounting frame is hollow and forms a frame shape around the protective frame, and a frame-shaped groove is provided on the side wall near the opening end of the protective frame, and a plurality of first magnetic pieces are provided in the frame-shaped groove; the diameter of the second magnetic piece is not greater than the width of the end face of the opening end of the protective cover; the number of second magnetic pieces is at least 4.

[0023] In some embodiments of the present invention, the diameter of the first magnetic sheet is not greater than the width of the frame groove; the number of the first magnetic sheets is at least four, preferably four, more preferably four, with the four first magnetic sheets respectively disposed in the groove on each side of the frame groove; the number of the second magnetic sheets is four, more preferably four, with the four second magnetic sheets respectively disposed on the end face of each side of the opening end of the protective cover; the end face of the opening end of the protective cover matches the frame groove and is detachably and movablely snapped together; the number of the first magnetic sheets and the second magnetic sheets are the same and their positions match; the first magnetic sheets and the second magnetic sheets are detachably and movablely connected by magnetic adsorption, which is used to connect the protective cover to the end face of the wire source block terminal on the mounting frame by magnetic adsorption to achieve sealing.

[0024] A second aspect of the present invention provides a method for operating a pressure-damage-free chromatograph, comprising one or a combination of two of the following methods:

[0025] Method 1) includes the following steps:

[0026] 11) Pull the latch from the pressure-free storage component and pull the movable block out of the groove of the extension body to separate the positioning strip from the second positioning slot;

[0027] 12) Under the rebound action of the first support spring, the wire source block returns to the position where the end face of the wire source block connection end is aligned with the end face of the storage frame opening end.

[0028] 13) Insert the movable block into the groove of the extension body so that the positioning strip is inserted into the first positioning slot;

[0029] 14) Connect the wiring to the wiring port of the line source block and start the main operation of the chromatograph;

[0030] When the liquid chromatograph is finished using, pull the latch to pull the movable block out of the groove of the extension body, so that the positioning strip separates from the first positioning slot. Press the wire source block to put the support spring into the contracted state, and the wire end of the wire source block enters the storage frame. Release the latch to return the first buffer spring to its original position, insert the movable block into the groove of the extension body, and insert the positioning strip into the second positioning slot to achieve positioning.

[0031] Method 2) includes the following steps:

[0032] 21) Pull the handle from the pressure-free sealing assembly to separate the first and second magnetic plates, and remove the protective cover;

[0033] 22) Connect the wiring to the wiring port of the line source block and start the main operation of the chromatograph.

[0034] When the liquid chromatograph is finished using the instrument, the opening end of the protective cover is engaged with the frame groove by the magnetic attraction of the first and second magnetic sheets, thus connecting the protective cover to the mounting frame and sealing the wiring terminals of the power source block.

[0035] Compared with the prior art, the beneficial effects of this invention are as follows: This invention provides protection against collisions and pressure damage to the exposed wire source blocks on the liquid chromatograph. The pressure-free storage component allows the wire source blocks to be embedded inside the storage frame when the liquid chromatograph is not in use, preventing collisions, squeezing, and accidental contact caused by exposed wire terminals. When in use, the wire source blocks extend, exposing the wire terminals to ensure normal wiring operation. Alternatively, the pressure-free sealing component can be used to seal and protect the wire source blocks, while the protective cover shields the wire terminals, preventing accidental contact and squeezing damage. A buffer spring further cushions impacts to the side of the pressure-free sealing component. The wire outlet holes and support springs within the storage or protective frame ensure consistent wiring direction, making wiring more orderly and preventing tangling and confusion. The handle or pull tab makes the use of the chromatograph more convenient. Therefore, this invention has a positive impact on the normal use of liquid chromatographs and meets practical usage needs. Attached Figure Description

[0036] Figure 1 This is a schematic diagram showing the connection between the pressure-free storage component and the line source block structure of the present invention.

[0037] Figure 2 This is a partial cross-sectional view showing the connection between the pressure-free storage component and the line source block structure of the present invention.

[0038] Figure 3 For the present invention Figure 2 Enlarged schematic diagram of the connection of the middle structure.

[0039] Figure 4 This is a schematic diagram showing the connection between the movable block and the positioning clip structure in the pressure-free storage component of the present invention.

[0040] Figure 5 This is a partial cross-sectional view of the internal structure of the slider on one side of the line source block of the present invention.

[0041] Figure 6 For the present invention Figure 5 Enlarged schematic diagram of the connection of the middle structure.

[0042] Figure 7 This is a schematic diagram showing the connection between the pressure-free sealing component and the line source block structure of the present invention.

[0043] Figure 8 This is a partial cross-sectional view showing the connection between the pressure-free sealing component and the line source block structure of the present invention.

[0044] Figure 9For the present invention Figure 7 Enlarged schematic diagram of the connection of the middle structure.

[0045] Figure 10 This is a schematic diagram of the protective cover structure connection of the present invention.

[0046] Figure 11 This is a partial cross-sectional view showing the connection between the protective frame and the second movable buffer block structure of the present invention.

[0047] In the diagram: chromatograph body 1, line source block 2, pressure-free storage assembly 3, storage frame 301, first support spring 302, first cable outlet 303, extension body 304, slide groove 305, slider 306, first slider segment 306A, second slider segment 306B, groove 307, first groove segment 307A, second groove segment 307B, movable block 308, positioning clip 309, pull buckle 310, return spring 311, first positioning slot 312, second positioning... Card slot 313, movable slot 314, first movable buffer block 315, first buffer spring 316, auxiliary inclined surface 317, pressure-free sealing component 4, protective frame 401, second support spring 402, second cable outlet hole 403, limit movable slot 404, second movable buffer block 405, second buffer spring 406, connecting plate 407, mounting frame 408, frame groove 409, first magnetic sheet 410, protective cover 411, second magnetic sheet 412, handle 413. Detailed Implementation

[0048] In the description of this invention, it should be noted that the structures, proportions, sizes, etc., illustrated in the accompanying drawings are merely for illustrative purposes to aid those skilled in the art and to facilitate understanding and reading. They are not intended to limit the implementation of this invention and therefore have no substantial technical significance. Any modifications to the structure, changes in proportions, or adjustments to size, without affecting the effectiveness and purpose of this invention, should still fall within the scope of the technical content disclosed in this invention. Furthermore, the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are merely for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention. In addition, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0049] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation", "connection", "linking", and "setting" should be interpreted broadly. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0050] The technical solutions in the embodiments of the present invention will be clearly and completely described below. All other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of the present invention.

[0051] Example 1

[0052] Please see Figures 1 to 6 The pressure-damage-free liquid chromatograph provided in Embodiment 1 of the present invention includes a chromatograph body 1, a line source block 2, and a pressure-free storage assembly 3. The pressure-free storage assembly 3 is used to store the line source block 2 and limit its position, protecting the line source block 2 from impact and accidental contact. The pressure-free storage assembly 3 includes a storage frame 301 to prevent direct impact of external forces on the line source block 2. The storage frame 301 is hollow and open at one end. The closed end of the storage frame 301 is connected to the side wall of the chromatograph body 1. The storage frame 301 contains... The first support spring 302 has one end connected to the closed end wall of the storage frame 301, and the other end connected to the wire source block 2 so that the wire source block 2 can be movably embedded into the open end of the storage frame 301, so that the wire source block 2 can be pushed into the storage frame 301 or the wiring end of the wire source block 2 can be aligned with the open end of the storage frame 301 so that the wiring end of the wire source block 2 is exposed. The closed end of the storage frame 301 is provided with a first wire outlet hole 303, which is connected to the side wall of the chromatograph body 1.

[0053] In the pressure-damage-free liquid chromatograph provided in Embodiment 1 of the present invention, an extension body 304 is provided on one side wall of the storage frame 301, and a groove 305 is provided on the inner side wall of the extension body 304. A slider 306 is provided on one side wall of the line source block 2. The slider 306 and the groove 305 are matched one-to-one so that the slider 306 slides and engages in the corresponding groove 305. A groove 307 is provided on the top surface of the extension body 304. The groove 307 is provided with a first groove segment 307A and a second groove segment 307B in sequence along the direction close to the line source block 2. The groove width of the first groove segment 307A along the axial direction perpendicular to the first groove segment 307A is greater than the groove width of the second groove segment 307B along the axial direction perpendicular to the first groove segment 307A. The groove 307 penetrates the extension body 304 and is used to accommodate the movable block 308 and the positioning strip 309. The position is defined by the insertion of the movable block 308 and the positioning strip 309 into the first positioning slot 312 and the second positioning slot 313.

[0054] In the pressure-damage-free liquid chromatograph provided in Embodiment 1 of the present invention, a movable block 308 is provided in the first groove section 307A, and a positioning strip 309 is provided on the movable block 308. One end of the positioning strip 309 is connected to the movable block 308, and the other end of the positioning strip 309 passes through the second groove section 307B and extends out of the extension body 304. A return spring 311 is sleeved on the positioning strip 309. One end of the return spring 311 is connected to the movable block 308, and the other end of the return spring 311 is connected to the groove wall of the first groove section 307A. The return spring 311 uses its elasticity to keep the movable block 308 and the positioning strip connected. Positioning strip 309 can be inserted into or pulled out of groove 307. When the return spring 311 is in normal state, positioning strip 309 is inserted into first positioning slot 312 or second positioning slot 313. Normal state is when the spring is not subjected to external force. When the return spring 311 is in tension state, positioning strip 309 is separated from first positioning slot 312 or second positioning slot 313. The movable block 308 is also provided with pull buckle 310. Pull buckle 310 is provided on the end face of movable block 308 away from positioning strip 309 and is used to pull movable block 308 which is movably set in groove.

[0055] In the pressure-damage-free liquid chromatograph provided in Embodiment 1 of the present invention, the slider 306 is divided into a first slider segment 306A and a second slider segment 306B. The first slider segment 306A and the second slider segment 306B are arranged sequentially in a direction away from the chromatograph body 1, and the sidewall of the first slider segment 306A is recessed inward relative to the second slider segment 306B. The sidewall of the first slider segment 306A is provided with a first positioning groove 312. The first positioning groove 312 is matched with the position of the second groove segment 307B so that the positioning strip 309 extends to the first positioning groove 312. The sidewall of the second slider segment 306B is also provided with a second positioning groove 313. The second positioning groove 313 is arranged away from the chromatograph body 1 relative to the first positioning groove 312. The slot 312 and the second positioning slot 313 have the same shape, both being trapezoidal, and the longitudinal section of the trapezoid gradually decreases along the direction closer to the chromatograph body 1; they are used to lock the line source block 2 when it retracts and extends relative to the storage frame. The second positioning slot 313 is connected to a movable slot 314. The movable slot 314 has 6 protruding first movable buffer blocks 315 on both sides of the slot body away from the chromatograph body 1. The slider 306 corresponding to the first movable buffer block 315 has a placement slot. There are 6 placement slots. The placement slots correspond one-to-one with the first movable buffer blocks 315. The number of placement slots on the opposite side wall of the movable slot 314 is the same, 3 in each case. The placement slots are set in opposite positions, and the interval between adjacent placement slots on the same side wall of the movable slot 314 is equal. A first buffer spring 316 is provided in the placement groove. One end of the first buffer spring 316 is connected to the groove wall of the placement groove, and the other end of the first buffer spring 316 is connected to the first movable buffer block 315. An auxiliary inclined surface 317 is provided at the end of the first movable buffer block 315 away from the first buffer spring 316. The auxiliary inclined surface 317 extends out of the placement groove, and the cross section of the auxiliary inclined surface 317 gradually decreases in the direction away from the first buffer spring 316. When the terminal of the wire source block 2 is still being squeezed, the wire source block 2 will continue to move towards the liquid chromatograph body 1. At this time, the positioning strip 309 will enter the movable groove 314 on the side of the second positioning groove 313 and contact the auxiliary inclined surface 317, squeezing the first movable buffer block 315. Under the action of the first buffer spring 316, the wire source block 2 is elastically buffered. It works in conjunction with the support spring 402 to give the pressure-free storage component 3 a good elastic protection function.

[0056] In the pressure-damage-free liquid chromatograph provided in Embodiment 1 of the present invention, the positioning strip 309 is detachably and movablely connected to the first positioning slot 312 and the second positioning slot 313 respectively.

[0057] Example 2

[0058] Please see Figures 6 to 10The microfluidic liquid chromatograph provided in Embodiment 2 of the present invention includes a liquid chromatograph body 1, a line source block 2, and a pressure-free sealing assembly 4. The pressure-free sealing assembly 4 is used to protect the line source block 2 from impact and accidental contact. The pressure-free sealing assembly 4 includes a protective frame 401, which is hollow and open at one end. The closed end of the protective frame 401 is connected to the side wall of the chromatograph body 1. The protective frame 401 protects the line source block 2 and blocks the impact of external forces. A second support spring 402 is provided inside the protective frame 401. One end of the second support spring 402 is connected to the closed end wall of the protective frame 401, and the other end of the second support spring 402 is connected to the line source block 2 so that the line source block 2 can be movably embedded into the open end of the protective frame 401. A protective cover 411 is detachably connected to the outside of the open end of the protective frame 401 to seal the line source block 2 and prevent external forces from impacting the terminal or accidental contact. The protective frame 401 has a second outlet hole 403 on its closed end, and the second outlet hole 403 is connected to the side wall of the chromatograph body 1.

[0059] In the pressure-damage-free microfluidic chromatograph provided in Embodiment 2 of the present invention, each of the four outer side walls of the protective frame 401 is provided with a limiting movable groove 404. A second movable buffer block 405 is provided in the limiting movable groove 404. A second buffer spring 406 is provided at both ends of the second movable buffer block 405. One end of the second buffer spring 406 is connected to the second movable buffer block 405, and the other end of the second buffer spring 406 is connected to the groove wall in the limiting movable groove 404. This makes the mounting frame 408 and the protective cover 411 have a good elastic buffering and protective effect, thereby improving the protection performance of the line source block 2. The top surface of the second movable buffer block 405 is connected to a connecting plate 407, which extends out of the limiting movable groove 404. The end of the connecting plate 407 away from the second movable buffer block 405 is connected to a mounting frame 408. The connecting plate 407 is used to connect to and support the mounting frame 408. The protective cover 411 is hollow and open at one end. Four second magnetic pieces 412 are provided on the end face of the open end of the protective cover 411. The four second magnetic pieces 412 are respectively provided on the end face of each side of the open end of the protective cover 411. A handle 413 is also provided on the closed end of the protective cover 411 to facilitate the installation and removal of the protective cover 411.

[0060] In the pressure-damage-free microfluidic chromatograph provided in Embodiment 2 of the present invention, a limiting movable groove 404 is disposed on the outer wall of the protective frame 401 near the opening end; the short side width of the opening of the limiting movable groove 404 is smaller than the short side width of the groove eye of the limiting movable groove 404, which is used to accommodate the second movable buffer block 405 and restrict the second movable buffer block 405 to move back and forth in a straight line only within the limiting movable groove 404; the second movable buffer block 405 is located at the center position of the limiting movable groove 404; the long side length of the second movable buffer block 405 is smaller than the long side length of the groove eye of the limiting movable groove 404. The width of the short side of the second movable buffer block 405 is not greater than the width of the short side of the slot of the limiting movable groove 404 and is greater than the width of the short side of the opening of the limiting movable groove 404, so that the second movable buffer block 405 can only move in the limiting movable groove 404; the mounting frame 408 is hollow and forms a frame around the protective frame 401, and a frame-shaped groove 409 is provided on the side wall near the opening end of the protective frame 401. Four first magnetic pieces 410 are provided in the frame-shaped groove 409, respectively located in the groove on each side of the frame-shaped groove 409; the diameter of the second magnetic piece 412 is not greater than the width of the end face of the opening end of the protective cover 411.

[0061] In the pressure-damage-free microfluidic chromatograph provided in Embodiment 2 of the present invention, the diameter of the first magnetic sheet 410 is not greater than the width of the frame groove 409, and the end face of the opening end of the protective cover 411 matches the frame groove 409 and is detachably and movablely snapped together; the number of the first magnetic sheet 410 and the second magnetic sheet 412 are the same and their positions are matched; the first magnetic sheet 410 and the second magnetic sheet 412 are detachably and movablely connected by magnetic adsorption, so that the protective cover 411 can be fixed on the end face of the wiring terminal of the online source block 2 to prevent impact and accidental contact to the wiring terminal.

[0062] Example 3

[0063] When using a pressure-free liquid chromatograph with a pressure-free storage component 3, first pull the pull tab 310 of the pressure-free storage component 3 outwards to disengage the movable block 308 from the groove 307 of the extension body 304 and separate the positioning clip 309 from the second positioning slot 313. At this time, the wire source block 2 extends out of the storage frame 301 under the rebound action of the first support spring 302, and the end face of the wire source block 2's wiring terminal aligns with the end face of the opening end of the storage frame 301, exposing the wiring port of the wire source block 2. Then, insert the movable block 308 into the groove 307 of the extension body 304 to insert the positioning clip 309 into the first positioning slot 312 to reposition the wire source block. Finally, connect the wiring port of the wire source block 2, and the chromatograph body 1 will operate normally.

[0064] When protecting the wire source block 2 using the pressure-free storage component 3, first pull the latch 310 at the end of the movable block 308 to separate the positioning strip 309 from the first positioning slot 312, thus releasing the positioning of the wire source block 2. Then press the wire source block 2 to make it enter the storage frame 301, ensuring that the wire end of the wire source block 2 is not exposed. Press the wire source block 2 until the second positioning slot 313 on the slider 306 is aligned with the positioning strip 309. Under the action of the return spring 311, the positioning strip 309 is engaged in the second positioning slot 313, achieving the repositioning of the wire source block 2. At this time, the wire source block 2 is connected to the second positioning slot 313. The first support spring 302 is compressed; and during this process, when the end of the wire source block 2 is still compressed, the wire source block 2 will continue to move into the storage frame 301. During this process, the positioning strip 309 will enter the movable groove 314 on the side of the second positioning groove 313 and compress the first movable buffer block 315 on both sides of the movable groove 314. Under the action of the first movable buffer block 315 and the first buffer spring 316, the wire source block 2 is elastically buffered, and then cooperates with the support spring 302 to make the pressure-free storage component 3 have a good elastic protection effect.

[0065] Example 4

[0066] When using a pressure-free microfluidic chromatograph with pressure-free sealing component 4, first pull outward the handle 413 of the pressure-free sealing component 4 to separate the first magnetic piece 410 and the second magnetic piece 412, thereby removing the protective cover 411. At this time, the wiring terminals of the line source block 2 are exposed, and the wiring is connected to the wiring port. The chromatograph body 1 then operates normally.

[0067] The protective frame 401 and the protective cover 411 work together to seal and protect the wire source block 2. The protective cover 411 is inserted into the mounting frame 408 and is fixed by the mutual attraction between the first magnetic piece 410 and the second magnetic piece 412. When it is hit, the protective cover 411 protects the wiring end of the wire source block 2. The mounting frame 408 has a good elastic buffering effect through the cooperation of the connecting plate 407, the second movable buffer block 405, the second buffer spring 406 and the limiting movable groove 404, which also provides a certain buffering protection for the protective cover 411, thereby improving the protection performance of the wire source block 2.

[0068] Compared to existing chromatographs, which lack protection for exposed wire sources, these instruments are susceptible to damage from impacts, pressure, and accidental contact during handling, installation, and use. Pressure-free storage and sealing components provide comprehensive protection for exposed wire sources. The storage or protective frame surrounding the wire source block blocks external impacts, while the wire terminals are either stored within the frame or sealed with protective covers to prevent accidental contact. The pull tabs and handles make these components easy to use. The cable outlets and support springs within the storage or protective frames ensure consistent wiring paths and organized storage, preventing tangling and confusion. These features significantly improve the ease of use and safety of pressure-free chromatographs, effectively extending their lifespan.

[0069] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A pressure-joint damage-free chromatograph comprising a chromatograph main body and a linear source block, characterized by: It also includes pressure-free storage components; The pressure-free storage component includes a storage frame, which is hollow and open at one end. The closed end of the storage frame is connected to the side wall of the chromatograph body. The line source block is movably embedded in the storage frame. The closed end of the storage frame is provided with a first line outlet hole, which is connected to the side wall of the chromatograph body. At least one extension body is provided on at least one side wall of the storage frame. The top surface of the extension body has a groove. The groove has a first groove segment and a second groove segment sequentially arranged along the direction close to the line source block, and the groove penetrates the extension body. A movable block is provided within the first groove segment, and a positioning strip is provided on the movable block. One end of the positioning strip is connected to the movable block, and the other end of the positioning strip penetrates the second groove segment and extends out of the extension body. A slider is provided on one side wall of the line source block. The slider is divided into a first slider segment and a second slider segment. The first slider segment and the second slider segment are sequentially arranged along the direction away from the chromatograph body, and the side wall of the first slider segment is recessed inward relative to the second slider segment. The wall is provided with a first positioning slot, which matches the position of the second groove segment so that the positioning strip extends to the first positioning slot. The side wall of the second slider segment is also provided with a second positioning slot, which is located away from the chromatograph body relative to the first positioning slot. The second positioning slot is connected to a movable groove. The movable groove has several protruding first movable buffer blocks on both sides of the groove body in the direction away from the chromatograph body. The slider corresponding to the first movable buffer block is provided with a placement groove. The placement groove corresponds to the first movable buffer block one by one. A first buffer spring is provided in the placement groove. One end of the first buffer spring is connected to the groove wall of the placement groove, and the other end of the first buffer spring is connected to the first movable buffer block.

2. A pressureless chromatography instrument according to claim 1, characterized in that: The chromatograph is selected from either a gas chromatograph or a liquid chromatograph.

3. A pressureless chromatography instrument according to claim 1, characterized in that: The storage frame is provided with a first support spring. One end of the first support spring is connected to the closed end wall of the storage frame, and the other end of the first support spring is connected to the wire source block so that the wire source block can be movably embedded into the open end of the storage frame. The inner sidewall of the extension is provided with a groove, and at least one slider is provided on at least one sidewall of the line source block. The slider and the groove are matched one-to-one so that the slider can slide and engage in the corresponding groove.

4. A pressure-damage-free chromatograph according to claim 3, characterized in that: The positioning clip is fitted with a return spring. One end of the return spring is connected to the movable block, and the other end of the return spring is connected to the groove wall of the first groove section. The movable block is also provided with a pull buckle, which is located on the end face of the movable block away from the positioning clip. The width of the first groove segment along the axial direction perpendicular to the first groove segment is greater than the width of the second groove segment along the axial direction perpendicular to the first groove segment.

5. A pressure-damage-free chromatograph according to claim 1, characterized in that: The positioning strip is detachably and movablely connected to the first positioning slot and the second positioning slot, respectively.

6. A pressure-damage-free chromatograph according to claim 1, characterized in that: The first movable buffer block has an auxiliary inclined surface at the end away from the first buffer spring. The auxiliary inclined surface extends into a placement groove, and the cross-section of the auxiliary inclined surface gradually decreases in the direction away from the first buffer spring.

7. A pressure-damage-free chromatograph according to claim 6, characterized in that: The first positioning slot and the second positioning slot have the same shape, and the shape of the first positioning slot and the second positioning slot is selected from one of the following: trapezoid, rectangle, square, triangle, circle, and polygon.

8. A pressure-damage-free chromatograph according to claim 5, characterized in that: The first positioning slot and the second positioning slot are trapezoidal in shape.

9. A pressure-damage-free chromatograph according to claim 8, characterized in that: The longitudinal section of the trapezoid gradually decreases in size as it approaches the main body of the chromatograph.

10. A pressure-damage-free chromatograph according to claim 1, characterized in that: The number of placement slots is at least 6.

11. A pressure-damage-free chromatograph according to claim 10, characterized in that: The number of placement slots is the same on the opposite wall of the movable slot, and the positions of the placement slots are opposite. The interval between adjacent placement slots on the same side wall of the movable slot is equal.

12. A method for operating a pressure-damage-free chromatograph, characterized in that, For operating the pressure-damage-free chromatograph as described in any one of claims 1 to 11, the operating method comprises the following steps: 11) Pull the latch from the pressure-free storage component and pull the movable block out of the groove of the extension body to separate the positioning strip from the second positioning slot; 12) Under the rebound action of the first support spring, the wire source block returns to the position where the end face of the wire source block connection end is aligned with the end face of the storage frame opening end; 13) Insert the movable block into the groove of the extension body so that the positioning strip is inserted into the first positioning slot; 14) Connect the wiring to the wiring port of the line source block and start the main operation of the chromatograph.

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