A chromatography laboratory cabinet

Abstract

The present invention discloses a chromatography laboratory cabinet, comprising: a cabinet body, a drug loading mechanism, a transfer mechanism, and a pressure-boosting and pressure-relieving mechanism. The pressure-boosting and pressure-relieving mechanism at least comprises a pressure relief device for performing a pressure-relieving operation on a transfer tube and a pressure booster for punching the drug in the drug loading tube into the drug loading tube and punching the drug in the drug loading tube into the chromatography column. The present invention realizes pre-loading of drugs through the drug loading mechanism, and realizes free conversion of drugs between the drug loading mechanism and the chromatography column by vacuuming through the pressure-boosting and pressure-relieving mechanism and the transfer mechanism, thereby realizing integrated automatic feeding and unloading. By adopting a closed experiment, there is no need to consider the harm to human labor caused by the pollution generated by the experiment, thus reducing labor costs, and automatic experiments improve experimental efficiency. In addition to manually placing experimental materials and replacing receiving pipes, the present invention can automatically load materials and automatically select the feed amount. Both stationary phase and mobile phase experiments can be automatically set and freely converted.

Description

Technical Field

[0001] The invention relates to the technical field of chromatography experiment cabinets, in particular to a chromatography experiment cabinet. Background Art

[0002] Chromatography is a method for separating and measuring multi-component mixtures according to the different stationary phase or mobile phase states of each component in the chromatographic column. It is often used to analyze components such as compounds or metal ions. Chromatography cabinets are special-purpose low-temperature cabinets developed specifically for chromatography experiments. They are suitable for experiments requiring a low-temperature environment, refrigerated items, and constant-temperature experiments on various components.

[0003] Most existing chromatography cabinets use semi-open chromatography systems. When faced with chromatography of different drugs and ingredients, most of them use manual mixing and testing, which reduces the constant temperature level in the cabinet, and the manual experimental errors are large. In addition, the volatilization of toxic organic solvents released during the experiment causes a lot of harm to personnel. Summary of the Invention

[0004] The technical problem to be solved by the present invention is to provide a chromatography laboratory cabinet which can maintain the temperature inside the cabinet and reduce the time of manual preparation.

[0005] In order to solve the above technical problems, the present invention adopts the following technical solution: a chromatography laboratory cabinet, comprising:

[0006] The cabinet has a charge area and a test area;

[0007] A charging mechanism, provided in the charging area, comprising at least a plurality of charging tubes for containing medicines;

[0008] A transfer mechanism is provided in the cabinet, can move between the charging area and the experimental area, and at least includes a transfer tube for receiving the medicine in the charging tube;

[0009] A chromatography column, located in the experimental area, for receiving the drug transported by the drug-loading tube and performing chromatography experiments;

[0010] The pressure boosting and pressure relief mechanism is arranged in the cabinet and comprises at least a pressure relief device for relieving pressure on the transfer pipe and a pressure booster for pressing the medicine in the charging tube into the charging tube and then pressing the medicine in the charging tube into the chromatography column.

[0011] Furthermore, the charging mechanism further includes a charging platform with a circular cross-section and arranged horizontally, and a driving member for controlling the rotation of the charging platform, and the plurality of charging tubes are spaced apart and respectively arranged on the outside of the charging platform.

[0012] Furthermore, the charging mechanism also includes a stretching assembly, the driving member includes a fixed shaft arranged on the cabinet, a rotating shaft connected to the fixed shaft, and a gear connected to the rotating shaft, the stretching assembly includes a mounting platform connected to the fixed shaft and two stretchers respectively arranged on the mounting platform and connected to the charging platform, and a gear ring is also provided on the inner side of the charging platform, and the gear can engage with the gear ring.

[0013] Furthermore, there are two transfer pipes, and the transfer mechanism also includes a horizontally arranged main shaft and auxiliary shafts rotatably arranged at both ends of the main shaft. The main shaft is rotatably arranged on the cabinet body, and the two transfer pipes are respectively vertically arranged on the two auxiliary shafts.

[0014] Furthermore, the boosting and pressure relief mechanism also includes a boosting tank connected to the pressure pipe and a boosting pipe connected to the boosting tank. The supercharger and the pressure relief device are rotatably arranged in the cabinet and are respectively located on the upper and lower sides of the transfer pipe, and the supercharger is connected to the boosting pipe, and the pressure relief device is connected to the pressure pipe.

[0015] Furthermore, the cabinet is provided with two mounting columns corresponding to the experimental area, and the two mounting columns are detachably provided with assembled cover plates, the assembled cover plates include a main cover plate and a receiving pipe connected to the main cover plate, and the receiving pipe can be connected to the transfer pipe, and the chromatography column can be detachably connected to the main cover plate and the mounting columns and connected to the receiving pipe.

[0016] Furthermore, the chromatography column includes a bottom chromatography column and multiple base chromatography columns, and the bottom chromatography column and the base chromatography column both include a column body and a mounting plate arranged on one side of the column body, and the mounting plate is provided with a mounting hole that can be detachably connected to the mounting column, and the two sides of the column body of the bottom chromatography column are respectively provided with a receiving hole and a recovery hole, and the two sides of the column body of the base chromatography column are respectively provided with a receiving hole, and the receiving holes of the column body of the base chromatography column can be communicated with the receiving holes of the column body of the bottom chromatography column.

[0017] Furthermore, the main cover is provided with a slot which can be engaged with the column.

[0018] Furthermore, it also includes a carrier and an elution tank arranged on the carrier, the booster tank is also arranged on the carrier, the carrier is rotatably arranged in the cabinet and can connect the elution tank or the booster tank with the booster pipe.

[0019] Furthermore, the column and the charge tube both have an observation screen for observing the interior.

[0020] The beneficial effects of the present invention are embodied in:

[0021] 1. Pre-loading of drugs is achieved through the drug loading mechanism, and the free transfer of drugs between the drug loading mechanism and the chromatography column is achieved through the pressure increasing and pressure releasing mechanism and the transfer mechanism by vacuum pumping, thus realizing integrated automatic loading and unloading;

[0022] 2. Using closed experiments, there is no need to consider the harm of pollution caused by the experiment to the human body, which reduces labor costs, and automatic experiments improve experimental efficiency;

[0023] 3. In addition to manually placing experimental materials and replacing receiving pipes, it can automatically load materials and automatically select feed volume. Stationary phase or mobile phase experiments can be automatically set and switched freely. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a front cross-sectional view of the chromatography laboratory cabinet structure of the present invention;

[0025] Figure 2 It is a schematic diagram of the structure of the charging mechanism of the present invention;

[0026] Figure 3 It is a schematic structural diagram of the transfer mechanism of the present invention;

[0027] Figure 4 This is a schematic diagram of the assembled cover structure of the present invention;

[0028] Figure 5 It is a schematic diagram of the structure of the bottom layer chromatography column and the base layer chromatography column of the present invention.

[0029] The components in the accompanying drawings are marked as follows: 1. Cabinet; 2. Charging mechanism; 201. Charging tube; 202. Charging platform; 203. Mounting platform; 204. Fixed shaft; 205. Rotating shaft; 206. Gear; 207. Ring gear; 208. Stretcher; 3. Transfer mechanism; 301. Transfer tube; 302. Secondary rotating shaft; 303. Main rotating shaft; 4. Chromatography column; 401. Bottom chromatography column; 4011. Column; 4012. Mounting Plate; 4013, mounting hole; 4014, receiving hole; 4015, recovery hole; 402, base chromatography column; 5, boosting and pressure relief mechanism; 501, pressure relief device; 502, booster; 503, pressure pipe; 504, boosting tank; 505, boosting pipe; 6, mounting column; 7, assembly cover; 701, main cover; 7011, card slot; 702, receiving pipe; 8, carrier; 9, elution tank; 10, loading layer. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. In the absence of conflict, the embodiments in this application and the features in the embodiments can be combined with each other. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0031] See also Figure 1 .

[0032] The chromatography experiment cabinet of the present invention comprises:

[0033] Cabinet 1, with charging area A and experimental area B;

[0034] The charging mechanism 2 is provided in the charging area A and comprises at least a plurality of charging tubes 201 for containing medicines;

[0035] The transfer mechanism 3 is provided in the cabinet 1 and can move between the charging area A and the experimental area B, and at least includes a transfer tube 301 for receiving the medicine in the charging tube 201;

[0036] The chromatography column 4 is located in the experimental area B and is used to receive the drug transported by the drug loading tube 201 and perform chromatography experiments;

[0037] The pressure-increasing and pressure-relieving mechanism 5 is disposed within the cabinet 1 and includes at least a pressure relief device 501 for relieving pressure from the transfer tube 301 and a pressure booster 502 for pressing the reagent in the charging tube 201 into the charging tube 201 and further pressing the reagent in the charging tube 201 into the chromatography column 4. In this embodiment, it should be noted that the pressure booster 502 and the pressure relief device 501 utilize structures available in the prior art that are connected to a retractable air pipe. The pharmacist manually injects the reagent in the charging tube 201, and the cabinet 1 is provided with doors for the corresponding charging area A and experimental area B.

[0038] In one embodiment, see Figure 1 , a plurality of charge shelves 10 are also provided in the cabinet 1. This design provides a placement area for the experimental reagents, making it convenient for them to inject the reagents into the charge tube 201.

[0039] In one embodiment, see Figure 1 and Figure 2The charging mechanism 2 further includes a horizontally disposed charging platform 202 having a circular cross-section and a drive member for controlling the rotation of the charging platform 202. The plurality of charging tubes 201 are spaced apart and positioned outside the charging platform 202. With this design, the plurality of charging tubes 201 can be sequentially moved to designated locations for unloading by rotating the charging platform 202.

[0040] In one embodiment, see Figure 1 The charging mechanism 2 also includes a stretching assembly, the driving member includes a fixed shaft 204 arranged on the cabinet 1, a rotating shaft 205 connected to the fixed shaft 204, and a gear 206 connected to the rotating shaft 205, the stretching assembly includes a mounting platform 203 connected to the fixed shaft 204 and two stretchers 208 respectively arranged on the mounting platform 203 and connected to the charging platform 202, and a ring gear 207 is also provided on the inner side of the charging platform 202, and the gear 206 can engage with the ring gear 207. With this design, when injecting medicine into the charging tube 201, the height of the charging platform 202 is first lowered by the stretching component to facilitate the injection. After the injection is completed, the height of the charging platform 202 is raised by the stretching component so that it engages with the gear 206. Finally, the rotation of the charging platform 202 needs to be adjusted by controlling the rotation of the rotating shaft 205. In this embodiment, the stretcher 208 can be obtained by existing technology and will not be described in detail here. The pull rope of the stretcher 208 is passed through the mounting platform 203 and connected to the charging platform 202, and the rotation of the rotating shaft 205 can be achieved by a motor.

[0041] In one embodiment, see Figure 3 Two transfer tubes 301 are provided, and the transfer mechanism 3 further includes a horizontally arranged main shaft 303 and secondary shafts 302 rotatably arranged at both ends of the main shaft 303. The main shaft 303 is rotatably arranged on the cabinet 1, and the two transfer tubes 301 are respectively vertically arranged on the two secondary shafts 302. This design, by providing two transfer tubes 301, can accelerate the transfer rate of the medicine in the charging tube 201, and the rotation of the secondary shaft 302 can facilitate the connection and alignment of the transfer tube 301 and the charging tube 201. In this embodiment, the rotation of the secondary shaft 302 and the main shaft 303 is achieved by a motor.

[0042] In one embodiment, see Figure 1The pressure-boosting and pressure-relieving mechanism 5 further includes a pressure pipe 503, a pressure-boosting tank 504 connected to the pressure pipe 503, and a pressure-boosting pipe 505 connected to the pressure-boosting tank 504. The pressure booster 502 and the pressure relief device 501 are rotatably arranged in the cabinet 1 and are respectively located on the upper and lower sides of the transfer pipe 301. The pressure booster 502 is connected to the pressure-boosting pipe 505, and the pressure relief device 501 is connected to the pressure pipe 503. With this design, when the pressure relief device 501 relieves the pressure of the transfer pipe 301, the gas in the transfer pipe 301 can enter the pressure relief device 501, and enter the pressure-boosting tank 504 through the pressure pipe 503, and then enter the pressure-boosting pipe 505 from the pressure relief device 504, and finally enter the pressure booster 502 to pressurize the transfer pipe 301 already filled with medicine, so as to realize the recycling of the gas inside the transfer pipe 301. Moreover, the gas inside the transfer pipe 301 itself has the effect of preventing contamination inside the pipe.

[0043] In one embodiment, see Figure 1 and Figure 4 The cabinet 1 is provided with two mounting columns 6 corresponding to the experimental area B, and the two mounting columns 6 are detachably provided with assembly covers 7. The assembly covers 7 include a main cover 701 and a receiving pipe 702 connected to the main cover 701. The receiving pipe 702 can be connected to the transfer pipe 301. The chromatography column 4 can be detachably connected to the main cover 701 and the mounting columns 6 and connected to the receiving pipe 702. This design allows the chromatography column 4 to be detachable and fixed, reducing the risk of the chromatography column 4 tipping over.

[0044] In one embodiment, see Figure 5 The chromatography column 4 includes a bottom chromatography column 401 and multiple base chromatography columns 402, and the bottom chromatography column 401 and the base chromatography column 402 both include a column body 4011 and a mounting plate 4012 arranged on one side of the column body 4011, and the mounting plate 4012 is provided with a mounting hole 4013 that can be detachably connected to the mounting column 6, and the column body 4011 of the bottom chromatography column 401 is respectively provided with a receiving hole 4014 and a recovery hole 4015 on both sides, and the column body 4011 of the base chromatography column 402 is respectively provided with a receiving hole 4014 on both sides, and the receiving hole 4014 of the column body 4011 of the base chromatography column 402 can be communicated with the receiving hole 4014 of the column body 4011 of the bottom chromatography column 401. This design enables the chromatography columns 4 to be spliced ​​together, so that the drugs that need chromatography can be independently placed in different base chromatography columns 402 or bottom chromatography columns 401. After all the drugs have entered the base chromatography columns 402 or bottom chromatography columns 401, they are connected to perform chromatography experiments. In this embodiment, the recovery hole 4015 of the bottom chromatography column 401 can be connected to an external recovery device.

[0045] In one embodiment, see Figure 4 The main cover 701 is also provided with a slot 7011 that can be snap-fitted with the column 4011. This design allows the column 4011 to fit tightly with the main cover 701 through the snap-fitting of the slot 7011 with the column 4011, facilitating communication between the receiving hole 4014 of the column 4011 and the receiving pipe 702.

[0046] In one embodiment, see Figure 1 , further comprising a carrier 8 and an elution tank 9 disposed on the carrier 8, the booster tank 504 also being disposed on the carrier 8. The carrier 8 is rotatably disposed within the cabinet 1 and can connect the elution tank 9 or the booster tank 504 to the booster pipe 505. With this design, after the experimental components in the chromatography column 4 are precipitated, the carrier 8 is rotated to connect the elution tank 9 to the booster pipe 505, and the booster 502 can be used to quickly elute the contents of the chromatography column 4, which is convenient and efficient, improving experimental efficiency.

[0047] In one embodiment, see Figure 5 The column 4011 and the charge tube 201 are both provided with an observation screen for observing the interior. This design makes it easy to know the content of the medicine.

[0048] In one embodiment, the charging tube 201 and the transfer tube 301 are provided with communication ports on both the upper and lower sides, and the communication ports, the receiving hole 4014, and the recovery hole 4015 are all provided with rubber rings. This design achieves both communication and sealing effects.

[0049] In one embodiment, the rotation centers of the platform 8, the transfer mechanism 3, the pressure relief device 501, and the pressure booster 502 are all on a straight line. This design rationally utilizes the space inside the cabinet and enhances the aesthetics of the cabinet body 1.

[0050] In summary, the present invention:

[0051] First, the required experimental components are removed from the charging compartment 10 and injected into the charging tube 201 on the charging platform 202. Then, the door of the charging area of ​​the cabinet 1 is closed, and the stretching assembly is activated. The charging platform 202 is stretched upward by the stretcher 208 until the ring gear 207 of the charging platform 202 is engaged with the gear 206.

[0052] The pressure-boosting and pressure-relieving mechanism 5 is activated, and the transfer pipe 301 and the pressure relief device 501 rotate in the same direction. The transfer pipe 301 is connected to the bottom of the charge tube 201 via the secondary rotating shaft 302. The pressure relief device 501 is connected to the bottom of the transfer pipe 301 through a telescopic air pipe. The gas inside the transfer pipe 301 is first extracted and sent to the pressure-boosting tank 504 through the pressure pipe 503.

[0053] The booster tank 504 is now connected to the booster pipe 505, which delivers gas to the booster 502 through the booster pipe 505. After the booster 502 collects the gas, it starts to rotate and connects the pressure pipe 503 to the upper part of the charging tube 201 through the telescopic air pipe. Then the booster 502 starts to work and injects pressurized gas into the charging tube 201, so that the experimental components inside the charging tube 201 quickly leave the charging tube 201, forming a high-speed jet and entering the connected transfer tube 301 from the bottom. It should be noted that the experimental components required for the bottom chromatography column 401 need to be injected first.

[0054] Whenever the booster 502 leaves the boosting pipe 505, the carrier 8 rotates to allow the boosting tank 504 to temporarily leave the valve port of the boosting pipe 505;

[0055] The pressurized gas transfer method can achieve quantitative and controllable transfer of experimental components, and the pressurized gas can fully clear the components inside the charging tube 201, thereby reducing consumption and achieving environmental protection. When the gas inside the supercharger 502 is exhausted, it can be rotated again to reach the pressurized pipe 505 to continue absorbing the pressurized gas. After the experimental components inside the current charging tube 201 are cleared, the charging platform 202 is driven to rotate by the rotating shaft 205. Since the charging platform 202 is engaged with the gear 206, the stability of the charging platform 202 during the rotation process is also guaranteed.

[0056] As the charging platform 202 rotates, the new charging tube 201 can be brought back to the working position, and the transfer tube 301 and the booster 502 can be connected at the same time, so as to continue working;

[0057] When the interior of the transfer tube 301 is full, the booster 502 stops working temporarily, and the transfer tube 301 rotates so that the new transfer tube 301 reaches the upper part of the charging tube 201. The previous work steps can be re-installed to pump out and charge the test materials and continue working. The transfer tube 301 filled with experimental components will reach the new working location. The two transfer tubes 301 will work simultaneously to ensure work efficiency.

[0058] The transfer tube 301 filled with experimental components will now reach the upper portion of the installation column 6. The experimental area B partition door is then opened, and the bottom chromatography column 401 is preferentially installed on the installation column 6. The assembly cover plate 7 is then connected to the bottom chromatography column 401 via the slot 7011, so that the receiving hole 4014 at the upper end of the bottom chromatography column 401 is connected to the receiving pipe 702. Simultaneously, the secondary rotating shaft 302 rotates the transfer tube 301 so that it is aligned with the receiving pipe 702. The experimental area B partition door is then closed. When the booster 502 completes its work on the charging end or the internal gas is exhausted, it returns to the booster pipe 505 to receive gas, and the chromatography column charging work is prioritized.

[0059] When the booster 502 starts working in the experimental area B, it will directly inject the pressurized gas from the booster 502 through the pressure pipe 503 into the transfer pipe 301 through the boosting pipe 505. The experimental components inside the transfer pipe 301 will be squeezed out and then enter the bottom chromatography column 401 through the receiving pipe 702. When the experimental components inside the transfer pipe 301 are emptied, the booster 502 is refilled with pressurized gas and continues to rotate back to the charging area for charging. The empty transfer pipe 301 will wait for the next charging operation. This cycle will continue until the observation screen confirms that the bottom chromatography column 401 has reached the required dose.

[0060] At this point, pause the work, open the partition door of experimental area B, pull the bottom chromatography column 401 downward along the installation column 6, remove the assembly cover 7 at the same time, install the assembly cover 7 on the base chromatography column 402, and continue the previous drug loading steps. However, be careful not to let the bottom receiving hole 4014 of the base chromatography column 402 connect to the bottom receiving hole 4014 of the bottom chromatography column 401 to prevent contamination before the chromatography begins. Then close the partition door;

[0061] When the multiple chromatography columns are filled with the desired experimental components, the columns are moved up and down by the mounting column 6 so that they are sequentially connected to each other through the receiving holes 4014. The recovery hole 4015 of the bottom chromatography column 401 needs to be connected to a recovery device. The pressure intensifier 502 is then used to slightly increase the pressure inside the receiving pipe 702 to start the stationary phase chromatography experiment, or to increase the pressure at full speed to start the rapid mobile phase chromatography experiment.

[0062] At this time, the staff only needs to stand outside the partition door to record the experiment. When the chromatography experiment is completed, the experimental components in the recovery device are re-injected into the loading platform 202, and then the loading platform 202 is connected to the pull rope of the tensioner 208 to realize the automatic cycle experiment.

[0063] When the experimental components in the chromatography column are analyzed, the tank rotation motor rotates the elution tank 9 connected to the booster pipe 505, and the booster 502 can quickly elute the chromatography column, which is convenient and fast, improving the experimental efficiency.

[0064] In summary, the present invention

[0065] 1. Pre-loading of drugs is achieved through the drug loading mechanism 2, and the free transfer of drugs between the drug loading mechanism 2 and the chromatography column 4 is achieved through the vacuum pumping method of the pressure increasing and pressure releasing mechanism 5 and the transfer mechanism 3, thus realizing integrated automatic loading and unloading;

[0066] 2. Using closed experiments, there is no need to consider the harm of pollution caused by the experiment to the human body, which reduces labor costs, and automatic experiments improve experimental efficiency;

[0067] 3. In addition to manually placing experimental materials and replacing the receiving pipe 702, it can automatically load materials and automatically select the feed amount. Stationary phase or mobile phase experiments can be automatically set and freely switched.

[0068] It should be understood that the examples and implementation methods described herein are for illustrative purposes only and are not intended to limit the present invention. Those skilled in the art may make various modifications or changes based on them. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

[0069] It should be noted that if the embodiments of the present invention involve directional indications such as up, down, left, right, front, back, etc., then the directional indications are only used to explain the relative position relationship, movement status, etc. between the various components under a certain specific posture as shown in the accompanying drawings. If the specific posture changes, the directional indication will also change accordingly.

[0070] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or suggesting their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited to "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the meaning of "and / or" appearing in the full text includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or schemes in which A and B are satisfied at the same time. In addition, "multiple" refers to more than two. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

Claims

1. A chromatography test cabinet, characterized in that: include: The cabinet (1) is provided with a charging area (A) and an experimental area (B); A charging mechanism (2), provided in the charging area (A), comprising at least a plurality of charging tubes (201) for containing medicines; A transfer mechanism (3) is provided in the cabinet (1), movable between the charging area (A) and the experimental area (B), and comprises at least a transfer tube (301) for receiving the medicine in the charging tube (201); A chromatography column (4) is provided in the experimental area (B) and is used to receive the drug transported by the drug loading tube (201) and perform chromatography experiments; A pressure boosting and pressure relief mechanism (5) is provided in the cabinet (1), and comprises at least a pressure relief device (501) for performing a pressure relief operation on the transfer tube (301) and a pressure booster (502) for pressing the medicine in the drug loading tube (201) into the transfer tube (301) and pressing the medicine in the transfer tube (301) into the chromatography column (4); Two transfer tubes (301) are provided, and the transfer mechanism (3) further comprises a horizontally arranged main rotating shaft (303) and auxiliary rotating shafts (302) rotatably arranged at both ends of the main rotating shaft (303); the main rotating shaft (303) is rotatably arranged on the cabinet (1), and the two transfer tubes (301) are respectively vertically arranged on the two auxiliary rotating shafts (302); The pressure-boosting and pressure-relieving mechanism (5) further comprises a pressure pipe (503), a pressure-boosting tank (504) connected to the pressure pipe (503), and a pressure-boosting pipe (505) connected to the pressure-boosting tank (504). The pressure booster (502) and the pressure relief device (501) are rotatably arranged in the cabinet (1) and are respectively located on the upper and lower sides of the transfer pipe (301). The pressure booster (502) is connected to the pressure-boosting pipe (505), and the pressure relief device (501) is connected to the pressure pipe (503).

2. The chromatography test cabinet according to claim 1, characterized in that: The charging mechanism (2) further comprises a charging platform (202) with a circular cross section and arranged horizontally, and a driving member for controlling the rotation of the charging platform (202), and a plurality of charging tubes (201) are spaced apart and respectively arranged outside the charging platform (202).

3. The chromatography test cabinet according to claim 2, characterized in that: The charging mechanism (2) further includes a stretching assembly, wherein the driving member includes a fixed shaft (204) arranged on the cabinet (1), a rotating shaft (205) connected to the fixed shaft (204), and a gear (206) connected to the rotating shaft (205); the stretching assembly includes a mounting platform (203) connected to the fixed shaft (204) and two stretchers (208) respectively arranged on the mounting platform (203) and connected to the charging platform (202); and a gear ring (207) is further provided on the inner side of the charging platform (202), and the gear (206) can mesh with the gear ring (207).

4. The chromatography test cabinet according to claim 1, characterized in that: The cabinet (1) is provided with two mounting columns (6) corresponding to the experimental area (B), and the two mounting columns (6) are detachably provided with an assembly cover (7), the assembly cover (7) includes a main cover (701) and a receiving pipe (702) connected to the main cover (701), and the receiving pipe (702) can be connected to the transfer pipe (301), and the chromatography column (4) can be detachably connected to the main cover (701) and the mounting columns (6) and connected to the receiving pipe (702).

5. The chromatography test cabinet according to claim 4, characterized in that: The chromatography column (4) includes a bottom chromatography column (401) and a plurality of base chromatography columns (402), and the bottom chromatography column (401) and the base chromatography column (402) each include a column body (4011) and a mounting plate (4012) arranged on one side of the column body (4011), and the mounting plate (4012) is provided with a mounting hole (4013) that can be detachably connected to the mounting column (6), and the bottom chromatography column (401) A receiving hole (4014) and a recovery hole (4015) are respectively provided on both sides of the column (4011) of the base chromatography column (402), and a receiving hole (4014) is respectively provided on both sides of the column (4011) of the base chromatography column (402), and the receiving hole (4014) of the column (4011) of the base chromatography column (402) can be connected to the receiving hole (4014) of the column (4011) of the bottom chromatography column (401).

6. The chromatography test cabinet according to claim 5, characterized in that: The main cover plate (701) is also provided with a slot (7011) that can be engaged with the column (4011).

7. The chromatography test cabinet according to claim 5, characterized in that: It also includes a carrier (8) and an elution tank (9) arranged on the carrier (8), the boosting tank (504) is also arranged on the carrier (8), and the carrier (8) is rotatably arranged in the cabinet (1) and can connect the elution tank (9) or the boosting tank (504) to the boosting pipe (505).

8. The chromatography test cabinet according to claim 5, characterized in that: The column (4011) and the charge tube (201) both have an observation screen for observing the interior.

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