Portable drug metabolism kinetic device

Abstract

This application relates to a portable pharmacokinetic device, belonging to the field of pharmacokinetic technology. It includes a storage base on which several test dishes are detachably mounted, arranged in at least two rows or columns. Several sliding covers are slidably mounted on the storage base, each corresponding to a test dish and capable of sealing it. Several clamping members are also mounted on the storage base, each corresponding to a test dish and holding a recording label. This application effectively reduces the likelihood of experimenters misclassifying test dishes or omitting them altogether when labels fall off, thus affecting experimental data.

Description

Technical Field

[0001] This application relates to the field of drug metabolism kinetics technology, and in particular to a portable drug metabolism kinetics device. Background Technology

[0002] Pharmacokinetics, or pharmacodynamics for short, primarily studies the dynamic changes in how the body processes drugs. It includes the absorption, distribution, biochemical transformation (or metabolism), and excretion of drugs within the body, particularly the changes in blood drug concentration over time. Drug metabolism is related to factors such as age, sex, individual differences, and genetic factors.

[0003] Before conducting clinical trials, it is generally necessary to establish rat PBPK (physiological pharmacokinetic model) and virtual human PBPK, which both require the use of test dishes for in vitro experiments.

[0004] Regarding the aforementioned technologies, since different drug dosages can lead to different experimental results, multiple sets of experimental data are generally needed for comparison in order to explore the method and concentration of drug use and improve drug efficacy. This requires multiple test dishes. Since existing test dishes are usually single and simply placed on the test bench or in the test chamber, labels are typically affixed to the lids to reduce confusion with control dishes. However, drug pharmacokinetics studies generally require placing the test dishes in multiple instruments (such as NMR spectrometers and mass spectrometers) to extract data. When multiple test dishes are transported to different laboratories for data extraction, it is inconvenient for researchers to categorize and arrange them. Furthermore, labels may fall off during transport, making it easy for researchers to not know the conditions under which the test dish was used, leading to misclassification or even disuse of the dish, resulting in erroneous or lost experimental data and ultimately affecting the accuracy of the experimental results. Summary of the Invention

[0005] To reduce the possibility of experimenters misclassifying or refusing to use test dishes due to label detachment, thereby affecting experimental data, this application provides a portable drug metabolism kinetic device.

[0006] The portable pharmacokinetic device provided in this application adopts the following technical solution:

[0007] A portable pharmacokinetic device includes a storage base on which a plurality of test dishes are detachably mounted, the test dishes being arranged in at least two columns or two rows. A plurality of sliding covers are slidably mounted on the storage base, each corresponding to one of the test dishes and capable of sealing the test dishes. A plurality of clamping members are provided on the storage base, each corresponding to one of the test dishes, and each clamping member holds a recording label.

[0008] By adopting the above technical solution, during the experiment, the experimenter can use test dishes in the same column as test groups with different reagent concentrations under the same environmental conditions, and test dishes in the same row as test groups with the same reagent concentration under different environmental conditions. After the slide cap is used to seal the culture dish, the record label is recorded or numbered, and then the record label is clamped with the clamping device. This makes it easy to store multiple test dishes in the same test group. The experimenter can take the storage base to other laboratories for data analysis without disturbing the order of the test dishes. In this way, even if the record label falls off during transportation, the experimenter can still infer the reagent concentration and environmental conditions of the test dish by looking at other record labels on the storage base. This reduces the possibility of the experimenter misclassifying the test dish or not knowing which test group the test dish belongs to and directly not using the test dish, thereby reducing the impact on the experimental data.

[0009] Optionally, the storage base has several storage slots, each corresponding to a test dish and located on one side of the test dish. A linkage is provided in each storage slot, and the clamping member and the sliding cover are simultaneously connected to the linkage. The clamping member is slidably disposed in the storage slot.

[0010] When the sliding cover is separated from the test dish, the clamping member is located in the storage groove;

[0011] When the sliding cover seals the test dish, the clamping member extends from the storage slot.

[0012] By adopting the above technical solution, when the sliding cover covers the test dish, the sliding cover drives the linkage to operate, causing the linkage to drive the clamping part to extend out of the storage slot, thus making it convenient for the experimenter to clamp the recording label on the clamping part.

[0013] After use, the experimenter opens the sliding cover, which moves the linkage to retract the clamping part into the storage slot. After the experimenter takes out the test dish, multiple storage bases can be stacked, which is convenient for stacking and storing multiple storage bases and reduces the storage space occupied by the storage bases.

[0014] Optionally, the linkage includes a first link hinged to the sliding cover, the first link being located between the clamping member and the sliding cover, the first link being hinged to a swing arm, the swing arm being hinged within the storage groove, and a second link hinged to the end of the swing arm away from the first link, the second link being hinged to the clamping member.

[0015] By adopting the above technical solution, when the sliding cover moves towards the test dish, the sliding cover drives the first connecting rod to move, the first connecting rod pulls the swing rod to swing, the swing rod pushes the second connecting rod upward, and the second connecting rod drives the clamping part to rise and rise out of the storage slot.

[0016] Optionally, the clamping member includes a connecting block, the connecting block is connected to a guide rod, a guide sleeve is provided in the storage groove, the guide rod is inserted into the guide sleeve, and a first elastic clip is provided on the connecting block, the first elastic clip clamping the recording tag.

[0017] By adopting the above technical solution, when the connecting block rises, the guide rod moves along the axis of the guide sleeve, which plays a guiding role for the connecting block, so that the connecting block can be raised and lowered stably. The first elastic clip can help the experimenter fix the recording label.

[0018] Optionally, the storage base has a plurality of injection channels, and the test dish has an injection port. The injection channels correspond one-to-one with the test dishes and are connected to the injection ports. The storage base is provided with a plurality of injection components. The injection components correspond one-to-one with the injection channels and are connected to them. The injection components are used to quantitatively extract the drug solution into the injection channels and then inject the drug solution into the test dish through the injection ports.

[0019] By adopting the above technical solution, the experimenter inserts the medicine bottle into the injection channel, and the injection component can draw the medicine into the injection channel and then inject it into the test dish through the injection port. The experimenter does not need to use a traditional syringe. One hand holds the medicine bottle and the other hand holds the syringe to draw the medicine, which makes it convenient for the experimenter to input the medicine into the test dish.

[0020] Optionally, the injection assembly includes an injection tube that communicates with the injection channel, an injection push rod that slides inside the injection tube, a sealing plate that is provided inside the injection channel, an inlet on the sealing plate, and a suction needle that is connected to the sealing plate and communicates with the inlet.

[0021] A first cap is hinged to the sealing plate. A torsion spring is provided on the hinge axis between the first cap and the sealing plate. The first cap abuts against the side of the sealing plate facing the test dish and seals the liquid inlet.

[0022] A second cap is hinged to the test dish. A torsion spring is also provided on the hinge axis between the second cap and the test dish. The second cap is hinged to the inner wall of the test dish and seals the injection port.

[0023] By adopting the above technical solution, the experimenter first inserts the medicine bottle into the injection channel and inserts the aspiration needle into the medicine bottle. Then, the experimenter pulls the injection plunger upward, which reduces the pressure in the space connecting the injection tube and the injection channel, opening the first cap. The medicine is drawn into the injection channel and injection tube between the first and second caps. The experimenter observes the scale on the injection tube. When the required dosage is reached, the experimenter pushes the injection plunger downward. Under the action of the torsion spring and pressure, the first cap seals the inlet, and the second cap flips to connect the injection port with the injection channel. The medicine is then injected into the test dish, making it convenient for the experimenter to complete the medicine injection into the test dish.

[0024] Optionally, the storage base has several placement slots, and the test dish corresponds to and is adapted to each of the placement slots. The test dish is placed in the placement slot, and the storage base is provided with a gripping member for removing the test dish from the placement slot.

[0025] By adopting the above technical solution, the design of the placement slot makes it convenient for the experimenter to position the test dish on the storage base, reducing the possibility of the test dish falling during transportation. When the test dish needs to be removed for cleaning after the test, the experimenter can take out the gripper on the storage base and use the gripper to quickly remove the test dish from the placement slot.

[0026] Optionally, the gripper includes a fixing block, a fixing sleeve is provided inside the fixing block, a connecting sleeve is provided inside the fixing sleeve, a second elastic clamp is connected to the connecting sleeve, the second elastic clamp extends out from the fixing sleeve, and an adjusting rod is threadedly connected to the fixing block. The adjusting rod passes through the fixing sleeve, the connecting sleeve and the second elastic clamp in sequence.

[0027] When the adjusting rod expands the second elastic clip, the second elastic clip can press against the inner wall of the test dish.

[0028] By adopting the above technical solution, when grasping the test dish, the second elastic clip is inserted into the test dish, and then the adjusting rod is rotated. The adjusting rod gradually passes through the second elastic clip, and the second elastic clip is opened by the adjusting rod and then tightens the test dish. Then the adjusting rod is lifted upward, and the adjusting rod drives the fixing block, connecting sleeve, second elastic clip and test dish to be lifted, thereby facilitating the separation of the test dish from the placement slot.

[0029] Optionally, an anti-slip pad is provided on the side of the second elastic clip that abuts against the test dish.

[0030] By adopting the above technical solution, the anti-slip pad can reduce the occurrence of the test dish slipping off the second elastic clip when the test dish is removed.

[0031] Optionally, a sealing gasket is provided on the side of the sliding cover facing the test dish, and when the sliding cover covers the test dish, the sealing gasket is in contact with the inner peripheral wall of the test dish;

[0032] The storage base has a pin groove, and the sliding cover has a pin. After the sliding cover covers the test dish, the pin passes through the sliding cover and extends into the pin groove.

[0033] By adopting the above technical solution, the sealing gasket plays a sealing role, which can reduce the leakage of liquid in the test dish during transportation. After the sliding cover covers the test dish, the pin is passed through the sliding cover and inserted into the pin groove to fix the sliding cover.

[0034] In summary, this application includes at least one of the following beneficial technical effects:

[0035] 1. During the experiment, the experimenter can group the test dishes in the same column as test groups with different reagent concentrations under the same environmental conditions, and the test dishes in the same row as test groups with the same reagent concentration under different environmental conditions. After the slide cap is used to seal the culture dish, the record label is recorded or numbered, and then the record label is clamped with the clamping device. This makes it easy to store multiple test dishes in the same test group. The experimenter can take the storage base to other laboratories for data analysis without disturbing the order of the test dishes. In this way, even if the record label falls off during transportation, the experimenter can still infer the reagent concentration and environmental conditions of the test dish by looking at other record labels on the storage base. This reduces the possibility of the experimenter misclassifying the test dish or not knowing which test group the test dish belongs to and directly not using the test dish, thereby reducing the impact on the experimental data.

[0036] 2. The experimenter first inserts the medicine bottle into the injection channel and inserts the aspiration pillow into the medicine bottle. Then, the experimenter pulls the injection plunger upwards. This reduces the pressure in the space connecting the injection tube and the injection channel, opening the first cap. The medicine is drawn into the injection channel and injection tube between the first and second caps. The experimenter observes the scale on the injection tube. When the required dosage is reached, the experimenter pushes the injection plunger downwards. Under the action of the torsion spring and pressure, the first cap seals the inlet, and the second cap flips over to connect the injection port with the injection channel. The medicine is then injected into the test dish, facilitating the experimenter's injection of medicine into the test dish. Attached Figure Description

[0037] Figure 1 This is a schematic diagram of the overall structure of an embodiment of this application.

[0038] Figure 2 This is a schematic diagram illustrating the structure of the injection component and the first elastic clip in an embodiment of this application.

[0039] Figure 3 This is a schematic diagram illustrating the structure of the linkage in an embodiment of this application.

[0040] Figure 4 This is a schematic diagram illustrating the structure of the torsion spring and the first cover in an embodiment of this application.

[0041] Figure 5 This is a schematic diagram illustrating the structure of the torsion spring and the second cover in an embodiment of this application.

[0042] Figure 6 This is a schematic diagram illustrating the structure of the gripper in an embodiment of this application.

[0043] Explanation of reference numerals in the attached drawings: 1. Storage base; 11. Injection channel; 12. Placement slot; 13. Storage slot; 14. Pin slot; 2. Test dish; 21. Injection port; 3. Gripper; 31. Fixing block; 32. Fixing ring; 33. Fixing sleeve; 34. Connecting sleeve; 35. Second elastic clamp; 36. Adjusting rod; 37. Anti-slip pad; 4. Sliding cover; 41. Sealing gasket; 42. Pin; 5. Linkage component; 51. First connecting rod; 52. Swing rod; 53. Second connecting rod; 6. Clamping component; 61. Connecting block; 62. Guide sleeve; 63. Guide rod; 64. First elastic clamp; 7. Recording label; 8. Injection assembly; 81. Injection tube; 82. Injection pusher; 83. Sealing plate; 831. Liquid inlet; 84. Aspiration needle; 85. First cap; 86. Torsion spring; 87. Second cap. Detailed Implementation

[0044] The following is in conjunction with the appendix Figure 1-6 This application will be described in further detail.

[0045] This application discloses a portable drug metabolism kinetic device.

[0046] like Figure 1 The portable pharmacokinetic device includes a storage base 1, with three injection channels 11 on each side of the storage base 1, and six placement slots 12 on the top surface of the storage base 1. The placement slots 12 correspond one-to-one with the injection channels 11 and are connected. The top surface of the storage base 1 also has six storage slots 13, which correspond one-to-one with the placement slots 12.

[0047] Each placement slot 12 contains a test dish 2. The outer side wall of the test dish 2 is in contact with the side wall of the placement slot 12. The top surface of the test dish 2 is flush with the top surface of the storage base 1. The six test dishes 2 are arranged in two rows and two columns. A gripping device 3 for removing the test dishes 2 from the placement slot 12 is hung on one side of the storage base 1.

[0048] like Figure 1 , Figure 2 and Figure 3 The storage base 1 has six sliding covers 4 connected to it. Each sliding cover 4 corresponds to a test dish 2 and can close the opening of the test dish 2. When the sliding cover 4 is open, the sliding covers 4 and test dishes 2 in the same row are arranged at intervals. The bottom surface of the sliding cover 4 is fixed with a sealing gasket 41. The storage base 1 has six pin grooves 14. When the sliding cover 4 is closed, the sealing gasket 41 fits against the inner circumferential wall of the opening of the test dish 2. The sliding cover 4 is provided with a pin 42, which is inserted into the pin groove 14.

[0049] The storage slot 13 is provided with a linkage 5 and a clamping member 6. The linkage 5 is connected to the sliding cover 4 and the clamping member 6. The clamping member 6 holds a recording label 7. When the sliding cover 4 is in the open state, the clamping member 6 and the recording label 7 are located in the storage slot 13. When the sliding cover 4 is in the closed state, the clamping member 6 and the recording label 7 extend out of the storage slot 13.

[0050] Each test dish 2 has an injection port 21 on its side wall, which is connected to the injection channel 11. An injection assembly 8 is provided on the storage base 1. The injection assembly 8 is used to quantitatively extract the drug into the injection channel 11 and inject the drug into the test dish 2 through the injection port 21.

[0051] Before the experiment, each test dish 2 is placed in the corresponding placement slot 12, and the medicine bottle is inserted into the injection channel 11. The injection component 8 can draw the medicine into the injection channel 11 and then inject it into the test dish 2 through the injection port 21. The experimenter does not need to use a traditional syringe. He holds the medicine bottle with one hand and the syringe with the other hand to draw the medicine, which makes it convenient for the experimenter to input the medicine into the test dish 2.

[0052] Depending on the dosage of the injected drug and the environmental conditions of the test dish 2, the experimenter can use test dishes 2 in the same column as test groups with different drug concentrations under the same environmental conditions, and test dishes 2 in the same row as test groups with the same drug concentration under different environmental conditions.

[0053] After the experimenter pulls the sliding cover 4 to seal the petri dish, the linkage 5 drives the clamping part 6 to extend from the storage slot 13. The experimenter records or numbers the information on the recording label 7. The test dishes 2 are placed in the corresponding placement slots 12 in sequence, which facilitates the storage of multiple test dishes 2 in the same experimental group. The experimenter can take the storage base 1 to other laboratories for data analysis without disrupting the order of the test dishes 2. In this way, even if the recording label 7 falls off during transportation, the experimenter can still infer the concentration of the reagent and the environmental conditions under which the test dish 2 was tested by looking at the other recording labels 7 on the storage base 1. This reduces the possibility that the experimenter will misclassify the test dish 2 or not know which experimental group the test dish 2 belongs to and directly not use the test dish 2, thereby reducing the impact on the experimental data.

[0054] After the experiment is completed, the experimenter opens the sliding cover 4. The sliding cover 4 drives the linkage 5 to move, causing the clamping part 6 to retract into the storage slot 13. The experimenter uses the gripping part 3 to take out the test dishes 2 one by one. Multiple storage bases 1 can be stacked, which is convenient for stacking multiple storage bases 1 and reducing the storage space occupied by the storage bases 1.

[0055] like Figure 2 and Figure 3 The clamping component 6 includes a connecting block 61, a guide sleeve 62 is provided on the side wall of the storage groove 13, a guide rod 63 is connected to the bottom of the connecting block 61, the guide rod 63 is inserted into the guide sleeve 62, and a first elastic clip 64 is fixed on the top surface of the connecting block 61, the first elastic clip 64 clamps the recording label 7.

[0056] The linkage 5 includes a first linkage 51, which is hinged to the side of the sliding cover 4 near the storage groove 13. The first linkage 51 is hinged to a swing rod 52, which is hinged to the inner wall of the storage groove 13 near the sliding cover 4. The swing rod 52 is hinged to a second linkage 53, which is hinged to the connecting block 61.

[0057] The first link 51 is located between the sliding cover 4 and the swing arm 52. The second link 53 is closer to the hinge axis between the swing arm 52 and the storage slot 13 than the first link 51. When the sliding cover 4 is fully closed, the first link 51 is in a horizontal state.

[0058] When the sliding cover 4 moves closer to the test dish 2, the sliding cover 4 drives the first connecting rod 51 to move. The first connecting rod 51 pulls the swing rod 52 to swing. The swing rod 52 pushes the second connecting rod 53 upward. The second connecting rod 53 drives the connecting block 61 to rise and rise out of the storage slot 13. When the connecting block 61 rises, the guide rod 63 moves along the axis of the guide sleeve 62, which plays a guiding role for the connecting block 61, so that the connecting block 61 can rise and fall stably. The first elastic clip 64 can help the experimenter fix the recording label 7.

[0059] like Figure 2 , Figure 4 and Figure 5 The injection assembly 8 includes an injection tube 81, which is threadedly connected to the top of the storage base 1. The injection tube 81 is connected to the injection channel 11. An injection push rod 82 is slidably disposed inside the injection tube 81. A sealing plate 83 is fixed inside the injection channel 11. The sealing plate 83 has a liquid inlet 831. A liquid suction needle 84 is connected to the side of the sealing plate 83 away from the test dish 2. The liquid suction needle 84 is connected to the liquid inlet 831.

[0060] A first cover 85 is hinged to the side of the sealing plate 83 facing the test dish 2. The first cover 85 abuts against the sealing plate 83 and closes the liquid inlet 831. A torsion spring 86 is sleeved on the hinge shaft between the first cover 85 and the sealing plate 83. One end of the torsion spring 86 is fixed on the hinge shaft, and the other end of the torsion spring 86 is fixed to the first cover 85.

[0061] A second cap 87 is hinged to the inner wall of the test dish 2. A torsion spring 86 is also fitted on the hinge shaft of the second cap 87 and the test dish 2. One end of the torsion spring 86 is fixed to the hinge shaft, and the other end of the torsion spring 86 is fixed to the second cap 87. The second cap 87 abuts against the outer wall of the test dish 2 and seals the injection port 21.

[0062] The experimenter first inserts the medicine bottle into the injection channel 11 and inserts the aspiration needle 84 into the medicine bottle. Then, the experimenter pulls the injection pusher 82 upward, which reduces the pressure in the space connecting the injection tube 81 and the injection channel 11. The first cap 85 opens, and the medicine is drawn into the injection channel 11 and the injection tube 81 between the first cap 85 and the second cap 87. The experimenter observes the scale on the injection tube 81. When the required amount of medicine is drawn, the experimenter pushes the injection pusher 82 downward. Under the action of the torsion spring 86 and pressure, the first cap 85 seals the inlet 831, and the second cap 87 flips over to connect the injection port 21 with the injection channel 11. The medicine is injected into the test dish 2, making it convenient for the experimenter to complete the medicine injection in the test dish 2.

[0063] like Figure 6 The gripper 3 includes a fixing block 31, a fixing ring 32 connected to the side wall of the storage base 1, the fixing block 31 is fitted inside the fixing ring 32, a fixing sleeve 33 is threaded inside the fixing block 31, a connecting sleeve 34 is fitted inside the fixing sleeve 33, a second elastic clip 35 is connected to the bottom of the connecting sleeve 34, the second elastic clip 35 extends out from the fixing sleeve 33, and an adjusting rod 36 is threaded to the fixing block 31. The adjusting rod 36 passes through the fixing sleeve 33 and the connecting sleeve 34 in sequence and enters the second elastic clip 35.

[0064] An anti-slip pad 37 is attached to the outer wall of the second elastic clip 35. When the second elastic clip 35 is inserted into the test dish 2 and the adjusting rod 36 is inserted into the second elastic clip 35, the second elastic clip 35 is opened by the adjusting rod 36 and then the anti-slip pad 37 presses against the test dish 2. Then the adjusting rod 36 is lifted upward, and the adjusting rod 36 drives the fixing block 31, the connecting sleeve 34, the second elastic clip 35 and the test dish 2 to be lifted, thereby facilitating the separation of the test dish 2 from the placement groove 12.

[0065] The implementation principle of this application embodiment is as follows: During the experiment, the experimenter can use test dishes 2 in the same column as test groups with different reagent concentrations under the same environmental conditions, and test dishes 2 in the same row as test groups with the same reagent concentration under different environmental conditions. After the sliding cover 4 seals the culture dish, the record label 7 is recorded or numbered, and then the record label 7 is clamped with the clamping piece 6, which facilitates the storage of multiple test dishes 2 in the same test group. The experimenter can take the storage base 1 to other laboratories for data analysis without disrupting the order of the test dishes 2. In this way, even if the record label 7 falls off during transportation, the experimenter can still infer the reagent concentration and environmental conditions of the test dish 2 through the other record labels 7 on the storage base 1, thereby reducing the possibility that the experimenter will misclassify the test dish 2 or not know which test group the test dish 2 belongs to and directly not use the test dish 2, thus reducing the impact on the experimental data.

[0066] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A portable drug metabolism kinetic device, characterized in that: Includes a storage base (1), on which a plurality of test dishes (2) are detachably mounted, the plurality of test dishes (2) being arranged in at least two columns or two rows, and a plurality of sliding covers (4) being slidably mounted on the storage base (1), the sliding covers (4) corresponding one-to-one with the test dishes (2) and capable of closing the test dishes (2), and a plurality of clamping members (6) being mounted on the storage base (1), the clamping members (6) corresponding one-to-one with the test dishes (2), and the clamping members (6) holding a record label (7); The storage base (1) has several injection channels (11), and the test dish (2) has an injection port (21). The injection channels (11) correspond one-to-one with the test dish (2) and are connected to the injection port (21). The storage base (1) is provided with several injection components (8). The injection components (8) correspond one-to-one with the injection channels (11) and are connected to each other. The injection components (8) are used to quantitatively extract the drug solution into the injection channel (11) and then inject the drug solution into the test dish (2) through the injection port (21). The injection assembly (8) includes an injection tube (81) connected to the injection channel (11), an injection push rod (82) slidably disposed inside the injection tube (81), a sealing plate (83) disposed inside the injection channel (11), an inlet (831) opened on the sealing plate (83), and a suction needle (84) connected to the sealing plate (83), the suction needle (84) connected to the inlet (831); A first cover (85) is hinged to the sealing plate (83). A torsion spring (86) is provided on the hinge axis between the first cover (85) and the sealing plate (83). The first cover (85) and the sealing plate (83) abut against the side of the test dish (2) and seal the liquid inlet (831). A second cap (87) is hinged to the test dish (2). A torsion spring (86) is also provided on the hinge axis between the second cap (87) and the test dish (2). The second cap (87) is hinged to the inner wall of the test dish (2) and seals the injection port (21).

2. The portable drug metabolism kinetic device according to claim 1, characterized in that: The storage base (1) has several storage slots (13), each of which corresponds to a test dish (2) and is located on one side of the test dish (2). A linkage (5) is provided in the storage slot (13), and the clamping member (6) and the sliding cover (4) are connected to the linkage (5) at the same time. The clamping member (6) is slidably disposed in the storage slot (13). When the sliding cover (4) is separated from the test dish (2), the clamping member (6) is located in the storage groove (13); When the sliding cover (4) covers the test dish (2), the clamping member (6) extends out from the receiving groove (13).

3. The portable drug metabolism kinetic device according to claim 2, characterized in that: The linkage (5) includes a first link (51), which is hinged to the sliding cover (4). The first link (51) is located between the clamping member (6) and the sliding cover (4). The first link (51) is hinged to a swing rod (52), which is hinged in the storage groove (13). The end of the swing rod (52) away from the first link (51) is hinged to a second link (53), which is hinged to the clamping member (6).

4. The portable drug metabolism kinetic device according to claim 2, characterized in that: The clamping member (6) includes a connecting block (61), the connecting block (61) is connected to a guide rod (63), a guide sleeve (62) is provided in the receiving groove (13), the guide rod (63) is inserted into the guide sleeve (62), and a first elastic clip (64) is provided on the connecting block (61), the first elastic clip (64) clamps the recording tag (7).

5. The portable drug metabolism kinetic device according to claim 1, characterized in that: The storage base (1) has several placement slots (12), and the test dish (2) corresponds to and is adapted to each of the placement slots (12). The test dish (2) is placed in the placement slot (12), and the storage base (1) is provided with a gripping member (3) for taking the test dish (2) out of the placement slot (12).

6. The portable drug metabolism kinetic device according to claim 5, characterized in that: The gripper (3) includes a fixing block (31), a fixing sleeve (33) is provided inside the fixing block (31), a connecting sleeve (34) is provided inside the fixing sleeve (33), a second elastic clip (35) is connected to the connecting sleeve (34), the second elastic clip (35) extends out from the fixing sleeve (33), and an adjusting rod (36) is threadedly connected to the fixing block (31). The adjusting rod (36) passes through the fixing sleeve (33), the connecting sleeve (34) in sequence and enters the second elastic clip (35). When the adjusting rod (36) expands the second elastic clip (35), the second elastic clip (35) can press against the inner wall of the test dish (2).

7. The portable drug metabolism kinetic device according to claim 6, characterized in that: The second elastic clip (35) is provided with an anti-slip pad (37) on the side that abuts against the test dish (2).

8. The portable drug metabolism kinetic device according to claim 1, characterized in that: The sliding cover (4) is provided with a sealing gasket (41) on the side facing the test dish (2). When the sliding cover (4) covers the test dish (2), the sealing gasket (41) is in contact with the inner peripheral wall of the test dish (2). The storage base (1) has a pin groove (14), and the sliding cover (4) has a pin (42). After the sliding cover (4) covers the test dish (2), the pin (42) passes through the sliding cover (4) and extends into the pin groove (14).

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