Mode-adjustable blood component separation device

Abstract

The application discloses a mode-adjustable blood component separation device and relates to the field of blood component separation equipment. The device comprises a support bottom plate and a support frame. A rotary swash plate mechanism for controlling blood component separation and a centrifugal collection mechanism for storing and collecting blood are arranged on the support frame, and the centrifugal collection mechanism is arranged at the front end of the rotary swash plate mechanism. The centrifugal collection mechanism is used for storing blood and collecting the plasma component in the uppermost layer of the separated blood; the rotary swash plate mechanism can control the rotation of the rotating disc on the same plane, thereby driving the blood in the centrifugal barrel to rotate at a high speed in an axial direction, and forming three layers of liquid surfaces of plasma, white blood cells and red blood cells. If the content of the extracted plasma does not reach the standard or better rapid separation effect needs to be achieved in a short time, the rotating disc is reciprocatingly axially inclined while rotating, so that the separation effect of the blood is improved.

Description

Technical Field

[0001] This invention relates to the field of blood component separation equipment, and more particularly to a mode-adjustable blood component separation device. Background Technology

[0002] With the continuous advancement of medical science and technology, component transfusion is a novel transfusion technique that has developed in recent decades. The emergence and development of component transfusion is a milestone in the progress of modern transfusion medicine, and it is significantly superior to whole blood transfusion. Compared with whole blood transfusion, component transfusion has the following advantages: 1. High purity and good efficacy; 2. Safe application and fewer side effects; 3. Good stability, easy to store and transport; 4. Comprehensive utilization and blood conservation. A necessary prerequisite for component transfusion is the separation of blood components. Blood centrifugation typically involves adding anticoagulants such as sodium citrate to the blood sample, then placing it in a centrifuge. Utilizing high rotation speed and the different densities of blood components, the blood is separated into layers. Blood centrifugation can generally separate blood into three relatively distinct layers: the plasma layer, the white blood cell and platelet layer, and the red blood cell layer.

[0003] The plasma layer, usually located at the top, is a pale yellow, transparent liquid containing water, proteins, glucose, inorganic salts, etc., and serves as the carrier for blood cells. The leukocyte and platelet layer is located in the middle layer, mainly containing neutrophils, basophils, monocytes, and platelets. The erythrocyte layer is located at the bottom layer, mainly composed of erythrocytes, and is a dark red, opaque solid.

[0004] Centrifugation is a commonly used clinical technique. By separating blood into layers through centrifugation, various blood components can be prepared into blood bags, such as plasma, red blood cell suspension, and apheresis platelets, facilitating clinical blood transfusion therapy. Plasma can also be used to prepare immunoglobulins, enhancing the immunity of immunodeficient or severely infected patients and neutralizing autoantibodies in patients with immune disorders. Specific immunoglobulins are immunoglobulin preparations made from plasma containing high-titer specific antibodies and can be used for patients infected with specific pathogens. In whole blood separation, the initial separation of blood components is achieved through static incubation, which has low efficiency. Furthermore, existing whole blood centrifugation equipment is generally large and expensive.

[0005] Therefore, there is an urgent need to design a blood component separation device that is low-cost, compact, and easy to use. For example, patent application CN114392844B discloses a blood component separation device for hematology. It includes a base, a frame, a first support, a rotating block, a rotating shaft, and a feeding frame. The frame is located at the top of the base, and the first support is located in the middle of the frame. The rotating block is rotatably mounted in the middle of the first support, and three rotating shafts are evenly rotated on the outer side of the rotating block. The feeding frame is located in the middle of the rotating shafts. This invention achieves rapid centrifugal separation of blood through the cooperation of a clamping mechanism, a rotating mechanism, and a transmission mechanism. The rotating mechanism drives the rotating block to rotate, and the rotating block drives the rotating shaft, the feeding frame, the clamping mechanism, and the container containing the blood to be separated to rotate together, thus achieving the effect of rapid centrifugal separation of blood.

[0006] However, the blood component separation device for hematology in the above-mentioned patent also has the following defects; (1) Its frame contains a large number of complex mechanical parts, which will inevitably generate a lot of noise when working. The excessive number of mechanical parts will result in a large size and weight of the entire device, making maintenance and repair more complicated and costly. At the same time, the equipment will be very difficult to move. It is inconvenient for medical staff to use.

[0007] (2) The structure is not designed to rotate the blood while creating an axial tilt to fully centrifuge and separate the blood into layers. This can easily lead to a low plasma content index and poor blood component separation effect. Summary of the Invention

[0008] To address the shortcomings of existing technologies, this invention proposes a blood component separation device for blood science that enables rapid centrifugation, avoids blood shaking, reduces separation costs, and enhances blood separation effects.

[0009] This invention discloses a mode-adjustable blood component separation device. It aims to reduce the overall manufacturing cost of the device, resulting in a smaller size, simpler structure, and easier operation by medical personnel.

[0010] To achieve the above objectives, the technical concept of this invention is as follows: (1) Control the annular guide rail and the adapter groove in the swashplate mechanism to form a sliding connection or separation state, and control the rotation angle, tilt and speed of the rotating disc through the rotating shaft, thereby controlling the rotation mode and speed of the centrifuge bucket, and flexibly select different durations and different methods of rotating the blood in the centrifuge bucket according to different situations.

[0011] (2) A centrifugal collection mechanism is set up, in which the lid and the sliding base are both slidably connected to the strip groove, so that medical staff can extract and collect the blood components after centrifugation in the centrifuge bucket, while delivering blood into the centrifuge bucket; the magnetic adsorption effect of the magnet is used to make the lid and the sliding base have a good fixing effect when there is no need to slide.

[0012] To achieve the above objectives, the technical solution adopted by the present invention is as follows: A mode-adjustable blood component separation device includes a support base plate and a support frame. The support frame is equipped with a rotary swashplate mechanism for controlling the separation of blood components and a centrifugal collection mechanism for storing and collecting blood. The centrifugal collection mechanism is located at the front end of the rotary swashplate mechanism.

[0013] Furthermore, the swashplate mechanism consists of a disc support, a threaded rod, a rotating disc, and a drive shaft; the drive shaft passes through the support frame, with a meshing guide rail at the rear end and a connection port at the front end; the bottom surface of the rotating disc has an arc-shaped connecting plate, which is rotatably connected to the connection port; a meshing disc is located at the rear end of the threaded rod, and the meshing disc meshes with the meshing guide rail; the disc support is symmetrically arranged at both ends of the drive shaft.

[0014] Specifically, the bottom surface of the rotating disk has a first and a second annular sliding groove, the first sliding groove is located inside the second sliding groove, and the two are set on the same horizontal plane.

[0015] To ensure that the blood centrifugation effect meets the standards, a further optimization of the present invention is as follows: sliding beads are symmetrically arranged in the first sliding groove and the second sliding groove, and the sliding beads are slidably connected to the first sliding groove and the second sliding groove; and an auxiliary spring is provided at the bottom of the sliding beads, and the auxiliary spring is fixedly connected to the support frame.

[0016] To facilitate the extraction of plasma from the top layer after component separation by medical personnel, a further optimized embodiment of the present invention is as follows: the centrifugation collection mechanism consists of a centrifuge bucket, a bucket lid, a sliding guide ring, and a syringe extraction assembly; the centrifuge bucket and the rotating disk are concentrically arranged and detachably connected; a centrifuge support is fitted onto the top of the centrifuge bucket, and the sliding guide ring is fixedly connected to the top of the centrifuge support; the bucket lid and the syringe extraction assembly are arranged inside the sliding guide ring, and strip grooves are symmetrically arranged at both ends of the sliding guide ring; the bucket lid and the syringe extraction assembly are slidably connected to the strip grooves, and the bucket lid and the syringe extraction assembly are fixedly connected.

[0017] In particular, the centrifuge support is a partially closed annular structure with notches.

[0018] In particular, the syringe extraction assembly includes a sliding base, a syringe support, a first syringe, a second syringe, and a gear shaft; the sliding base is a cylindrical structure with a hole at the center, and a syringe support is vertically arranged on the sliding base; a rotating gear shaft is arranged in the middle of the syringe support, a first syringe is arranged at the top of the syringe support, the lower end of the first syringe is sleeved with the second syringe, the centers of the first syringe, the second syringe, and the sliding base are coaxial, a rack bar is sleeved on the outer periphery of the second syringe, and the rack bar is perpendicular to and meshes with the rotating gear shaft.

[0019] Preferably, the syringe support is in a "冂"-shaped structure.

[0020] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) The swashplate mechanism can control the rotating disc to rotate first on the same plane, thereby driving the blood in the centrifuge bucket to perform high-speed axial centrifugal rotation, forming three liquid levels of plasma, white blood cells, and red blood cells. If the extracted plasma content does not meet the standard, the rotating disc will be reciprocally axially tilted while rotating to improve the blood separation effect.

[0021] (2) The way that both the bucket cover and the sliding base in the centrifugal collection mechanism are slidably connected to the strip-shaped chute facilitates medical staff to extract and collect the blood components in the centrifuge bucket after centrifugation, and also facilitates the transportation of blood into the centrifuge bucket. After extraction, if it is detected that the plasma content does not meet the standard, the movement of the bucket cover and the sliding base is also very convenient. And relying on the magnetic force of the magnet, a good fixing effect is achieved between the bucket cover, the sliding base, and the centrifuge bucket, and they will not loosen even when the centrifuge bucket rotates at high speed. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The invention will be further described below with reference to the drawings and embodiments.

[0023] Figure 1 is the usage state diagram of the mode-adjustable blood component separation device of the present invention; Figure 2 is Figure 1 the structural schematic diagram from another angle; Figure 3 is Figure 1 the top view of Figure 4 is Figure 1 the structural schematic diagram of the support bottom plate and the support frame in Figure 5 is Figure 1 the structural schematic diagram of the swashplate mechanism in Figure 6 is Figure 5 the structural schematic diagram from another angle; Figure 7 is Figure 6 the structural diagram of the drive shaft and its mating components in Figure 8 yes Figure 7 Installation and assembly diagram of the sliding ball and auxiliary spring; Figure 9 This is a structural diagram of the centrifugal collection mechanism in the adjustable blood component separation device of the present invention; Figure 10 yes Figure 9 A structural diagram from another angle; Figure 11 yes Figure 9 A sectional view; Figure 12 yes Figure 9 Cross-sectional view of the centrifuge tank; Figure 13 This is a diagram of the internal structure of a centrifuge tank; Figure 14 This is a diagram showing the connection relationship between the bucket lid and the sliding base; Figure 15 This is a structural diagram of a rotating disk; Figure 16 yes Figure 10 Diagram showing the fit between the rotating gear shaft and the rack. Figure 17 yes Figure 16 Diagram showing the relationship between the first and second syringes.

[0024] In the diagram: 1. Support base plate; 101. Support frame; 103. Support rod; 104. Threaded connection block; 2. Drive shaft; 201. Engaging guide rail; 202. Engaging groove; 203. Connection port; 3. Disc support; 301. Adapter slot; 4. Rotating disk; 401. Annular guide rail; 402. Mounting hole; 403. Rotating shaft; 404. Connecting plate; 405. First sliding groove; 406. Second sliding groove; 5. Centrifuge drum; 501. Mounting column; 502. Filter screen; 503. Placement tank; 6. Threaded rod; 601. Engaging disc; 602. Rotary joint; 7. Centrifuge support; 8. Sliding guide ring; 801. Strip groove; 9. Bucket lid; 901. Guide tube hole; 902. Magnet; 10. Auxiliary spring; 1001. Sliding pin; 12. Sliding base; 1201. Connecting stabilizing strip; 13. Needle holder; 14. Rotate the gear shaft; 1401. Turn the handle; 15. First syringe; 1501. Limiting block; 16. Second needle tube; 1601. Rack and pinion; 17. First sliding block; 18. Second sliding block. Detailed Implementation

[0025] To make the above-mentioned objects, features and advantages of the present invention more apparent and understandable, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0026] Many specific details are set forth in the following description in order to provide a full understanding of the invention. However, the invention may also be practiced in other ways different from those described herein, and those skilled in the art can make similar extensions without departing from the spirit of the invention. Therefore, the invention is not limited to the specific embodiments disclosed below.

[0027] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that is mutually exclusive with other embodiments. Example 1

[0028] Combination Figures 1 to 17 This invention discloses a mode-adjustable blood component separation device, including a supporting base plate 1 and a supporting frame 101. A rotary swashplate mechanism and a centrifugal collection mechanism are provided on the supporting frame 101. The centrifugal collection mechanism is used to store blood and collect the plasma at the top layer after blood component separation. The rotary swashplate mechanism can rotate and the rotation angle, tilt and speed can be controlled to achieve efficient and high-quality centrifugation of blood in the rotary swashplate mechanism, thereby achieving the effect of blood component separation.

[0029] Specifically, the swashplate mechanism consists of a disc support 3, a threaded rod 6, a rotating disc 4, and a drive shaft 2. The support base plate 1 is a cuboid structure, located at the bottom of the entire device, and makes stable contact with the ground. Two cylindrical support rods 103 are symmetrically arranged on the left and right sides of the front end of the support base plate 1. A support frame 101 for stably mounting the swashplate mechanism and the centrifugal collection mechanism is also provided on the support base plate 1. The support frame 101 is located behind the support rods 103.

[0030] The support frame 101 is hollow, with the drive shaft 2 extending through it in the front-to-back direction. The drive shaft 2 is located at the upper end of the support frame 101. Two rings of meshing guide rails 201 are arranged opposite each other on the rear end of the drive shaft 2, forming a meshing groove 202 between them. The meshing guide rails 201 and the rear end of the drive shaft 2 are integrally formed. A threaded connecting block 104 is located on the left side of the support frame 101. The threaded connecting block 104 is threadedly connected to a threaded rod 6 via a threaded hole. A meshing disc 601 is welded to the rear end of the threaded rod 6, rotatably connected to the meshing groove 202. A rotary joint 602 is also connected to the rear end of the meshing disc 601. When the rotary joint 602 is rotated, the threaded rod 6 moves forward or backward relative to the threaded connecting block 104. Simultaneously, the threaded rod 6 engages with the meshing groove 202 at the rear end of the drive shaft 2 through the meshing disc 601, driving the drive shaft 2 to move forward or backward.

[0031] A connection port 203 is provided at the front end of the drive shaft 2, and a connecting plate 404 is provided in the connection port 203. The connecting plate 404 has an arc-shaped structure and is rotatably connected to the connection port 203. In this embodiment, the rotatable connection is as follows: a rotating shaft 403 is vertically provided at the position of the connection port 203, and the rotating shaft 403 passes through the drive shaft 2 and the connecting plate 404. A rotating disk 4 is vertically provided at the front end of the connecting plate 404, and the connecting plate 404 is located at the rotation center of the rotating disk 4. The connecting plate 404 and the rotating disk 4 are fixedly connected. Furthermore, annular guide rails 401 are symmetrically arranged on the bottom and top surfaces of the rotating disk 4, and the annular guide rails 401 are integrally designed with the rotating disk 4. Semi-enclosed square-shaped disk supports 3 are symmetrically arranged on the left and right sides of the front end of the support frame 101, completely surrounding the rotating disk 4. The rear ends of the disk supports 3 are welded to the support frame 101, and the front ends of the disk supports 3 are fitted onto two support rods 103. Adaptive grooves 301 are symmetrically formed on the inner sides of the two disk supports 3, and the annular guide rails 401 are slidably connected to the adaptive grooves 301, with a transition fit. When the disk supports 3 are not subjected to axial force in the front-back direction, the rotating disk 4 will rotate smoothly. When the disk supports 3 are subjected to axial force in the front-back direction, the annular guide rails 401 on the rotating disk 4 will disengage from the adaptive grooves 301.

[0032] Furthermore, a first annular sliding groove 405 and a second annular sliding groove 406 are formed on the bottom surface of the rotating disk 4. The first sliding groove 405 is located inside the second sliding groove 406. The depth and height of the first sliding groove 405 and the second sliding groove 406 are equal, and they are set on the same horizontal plane. The radius of the second sliding groove 406 is larger than that of the first sliding groove 405. The centers of the first sliding groove 405 and the second sliding groove 406 are the same as the center of the rotating disk 4. The sliding marble is slidably connected to the first sliding groove 405 and the second sliding groove 406. The sliding marble has a structure of three spheres integrally formed. The sphere in the middle has a larger radius, and the spheres at both ends have smaller radii. The two smaller spheres have equal radii and are symmetrically arranged on both sides of the middle sphere. The number of sliding marbles is set to two, symmetrically arranged on both sides of the connection port 203.

[0033] Meanwhile, each of the two sliding balls is provided with an auxiliary spring 10 at its bottom end. The bottom end of the auxiliary spring 10 is connected to the support frame 101. The two auxiliary springs 10 are arranged in parallel and are both located inside the disc support 3.

[0034] Three mounting holes 402 are provided on the circumference of the top surface of the rotating disk 4. The centrifugal collection mechanism is connected to the swashplate mechanism through the mounting holes 402. The three mounting holes 402 are opened at equal angles with the rotation center of the rotating disk 4 as the center, and the distance between two adjacent mounting holes 402 is 120°.

[0035] The centrifugal collection mechanism consists of a centrifuge bucket 5, a bucket lid 9, a sliding guide ring, and a syringe extraction assembly. The center of the centrifuge bucket 5 is coaxial with the center of the rotating disk 4, and three mounting posts 501 are arranged on the bottom circumference of the centrifuge bucket 5. The mounting posts 501 are inserted into the mounting holes 402, and the mounting posts 501 and mounting holes 402 are interference fits. Therefore, the three mounting posts 501 are opened at equal angles along the center of the centrifuge bucket 5, with a 120° interval between adjacent mounting posts 501, to connect the centrifuge bucket 5 and the rotating disk 4, ensuring that the centrifuge bucket 5 can rotate when the rotating disk 4 rotates. The centrifuge bucket 5 is a hollow, topless bucket-shaped structure.

[0036] A centrifuge support 7 is fitted onto the top of the centrifuge tank 5. The centrifuge support 7 is a partially closed annular structure with a notch. A cubic placement groove 503 is provided on the centrifuge tank 5 at the position corresponding to the notch. A magnet 902 is placed in the placement groove 503, and the top surface of the magnet 902 is fixedly connected to the top of the tank lid 9. A sliding guide ring is welded to the top of the centrifuge support 7. The sliding guide ring is a square frame structure with an arc-shaped front end. The sliding guide ring is inclined, and strip grooves are symmetrically arranged at the upper and lower ends of the inner side of the sliding guide ring.

[0037] At the top of the centrifuge barrel 5, there is a barrel cover 9 adapted to it. At the position directly below the barrel cover 9, there is a filter net 502, and the filter net 502 is arranged at the top of the centrifuge barrel 5. And at the upper and lower ends of the outer surface of the bottom end of the barrel cover 9, first sliding blocks 17 are symmetrically arranged, and the first sliding blocks 17 are slidably connected with the strip-shaped chutes. At the position of the center of the sphere at the topmost end of the centrifuge barrel 5, a conduit hole 901 is opened for connecting a conduit. The conduit can transport blood into the centrifuge barrel 5 for blood separation operation.

[0038] At the right end of the bottom of the barrel cover 9, a syringe extraction assembly is connected through a connecting and stabilizing bar 1201. The syringe extraction assembly includes a sliding base 12, a syringe support 13, a first syringe 15, a second syringe 16 and a gear shaft. The right end of the connecting and stabilizing bar 1201 is welded to the barrel cover 9, and the left end is welded to the sliding base 12. The sliding base 12 is of a cylindrical structure, and the bottom surface of the sliding base 12 and the bottommost end of the barrel cover 9 are on the same horizontal plane and have the same radius. Therefore, both the sliding base 12 and the barrel cover 9 can form a good sealing effect with the top of the centrifuge barrel 5. And at the upper and lower ends of the sliding base 12, second sliding blocks 18 are symmetrically arranged, and the second sliding blocks 18 are slidably connected with the strip-shaped chutes.

[0039] On the upper surface of the sliding base 12, a syringe support 13 is vertically arranged. The bottom of the syringe support 13 is welded to the sliding base 12. The syringe support 13 is of a "冂" - shaped structure. In the middle of the syringe support 13, a rotating gear shaft 14 is arranged. The rotating gear shaft 14 is rotatably connected with the two side walls of the syringe support 13, and the rotating gear shaft 14 is parallel to the sliding base 12. And at the end of the rotating gear shaft 14, a rotating handle 1401 is arranged. At the top of the syringe support 13, a first syringe 15 is arranged. The lower end of the first syringe 15 is sleeved with the second syringe 16. At the uppermost end of the first syringe 15, a limiting block 1501 is arranged. The centers of the first syringe 15, the second syringe 16 and the sliding base 12 are coaxial. The radius of the first syringe 15 is larger than that of the second syringe 16, and the first syringe 15 penetrates through the top of the syringe support 13. A rack bar 1601 is sleeved on the outer periphery of the second syringe 16. The rack bar 1601 meshes with the rotating gear shaft 14. A hole is opened at the center of the sliding base 12 to facilitate the second syringe 16 and the gear shaft to pass through the sliding base 12 to extract the plasma located at the uppermost layer after blood centrifugation in the centrifuge barrel 5.

[0040] The usage process and working principle of this invention are as follows: By rotating the rotary joint 602, the threaded rod 6 is driven to rotate. Since the distance between the meshing disc 601 and the threaded connecting block 104 will change after the threaded rod 6 rotates, it is only necessary to adjust the position of the meshing disc 601. The meshing disc 601 cooperates with the meshing groove 202, and the length of the front end of the drive shaft 2 extending out of the support frame 101 can be adjusted, thereby adjusting the position of the rotating disc 4 in the front-rear direction. After the adjustment is completed, the annular guide rail 401 on the rotating disc 4 and the adapter groove 301 on the disc bracket 3 form a good fit, so that the annular guide rail 401 and the adapter groove 301 form a sliding connection.

[0041] The centrifugal collection mechanism is then connected to the rotating disk via the insertion connection between the mounting hole 402 and the mounting post 501. By rotating the rear end of the drive shaft 2 using a motor or other power source, the rotating disk 4 can be kept rotating on the same horizontal plane, thereby driving the centrifuge tank 5 to rotate at high speed, thus separating the blood in the centrifuge tank 5 through centrifugation. While the centrifuge tank 5 is rotating at high speed, since the bottom of the tank lid 9 is connected to a magnet 902, and a placement slot 503 for placing the magnet 902 is provided at the top of the centrifuge tank 5, the magnetic force of the magnet 902 will attract the tank lid 9 to the centrifuge tank 5, so that the tank lid 9 has reliable stability when the centrifuge tank 5 is rotating.

[0042] When the rotating disk 4 is working normally, the blood inside the centrifuge tank 5 undergoes axial centrifugal rotation, forming three layers of liquid: plasma, white blood cells, and red blood cells, with plasma at the top.

[0043] After the blood centrifugation operation is completed, push the bucket lid 9 diagonally upward along the strip groove. The bucket lid 9 and the magnet 902 will move towards the arc surface of the sliding guide ring. When the magnet 902 is attracted to the arc surface of the sliding guide ring, the bottom surface of the sliding base 12 is just completely attached to the top opening of the centrifuge bucket 5. At this time, the attraction between the magnet 902 and the sliding guide ring will stabilize the position of the sliding base 12.

[0044] Rotating the handle 1401 causes the gear shaft 14 to rotate, which in turn moves the rack 1601 downward, thereby moving the first needle 15 and the second needle 16 downward. The lower end of the second needle 16 penetrates into the centrifuge tank 5 to extract the plasma from the uppermost layer. The limiting block 1501 at the top of the first needle 15 can limit the downward movement of the second needle 16. Example 2

[0045] Based on Example 1, if the content of the plasma extracted from centrifuge tank 5 is not up to standard after testing, it indicates that the centrifugation stratification has not yet met the standard. In this case, the blood in centrifuge tank 5 needs to be axially centrifuged more thoroughly.

[0046] The specific operating steps are as follows: The sliding base 12 is moved horizontally to allow the lid 9 to cover the top of the centrifuge tank 5, and the magnet 902 enters the placement groove 503 to secure the lid 9. Then, the rotary joint 602 is rotated, causing the threaded rod 6 to move backward. Simultaneously, the engagement of the meshing disc 601 and the meshing groove 202 drives the drive shaft 2 to move backward, causing the annular guide rail 401 to disengage from the adapter groove 301. At this point, the rotating disc 4 is positioned at the middle of the front end of the disc support 3.

[0047] Then, a motor or other power source is used to make the drive shaft 2 rotate at high speed again, driving the rotating disk 4 to rotate. Since the front end of the drive shaft 2 has a connection port 203, a rotating shaft 403 is vertically arranged in the connection port 203, and the rotating shaft 403 passes through the drive shaft 2 and the connecting plate 404. Under the action of strong centrifugal force, the rotating disk 4 will tilt axially while rotating, driving the centrifuge barrel 5 connected above to perform a slant-plate rotational motion, that is, it rotates while tilting axially. When the centrifuge barrel 5 rotates in a slant-plate motion, the front end of the auxiliary spring 10 is provided with a sliding ball, which is slidably connected to the first sliding groove 405 and the second sliding groove 406, and the center of the first sliding groove 405 and the second sliding groove 406 is the same as the center of the rotating disk 4. The rear end of the auxiliary spring 10 is fixed to the support frame 101 to ensure that when the rotating disk 4 rotates in a slant-type motion, the eccentric motion stroke is too large and it rubs against both sides of the inner wall of the disk support 3. The auxiliary spring 10 has the characteristic of elastic deformation, which can increase the tilt angle of the rotating disk 4, thereby more fully centrifuging and stratifying the blood in the centrifuge tank 5, improving the stratification effect, and increasing the plasma content index to ensure that the centrifugation stratification is qualified. After this series of operations is completed, qualified plasma can be extracted through the first needle tube 15 and the second needle tube 16.

[0048] Example 3 Application Case This embodiment describes the application of the present invention in the field of blood component separation equipment. By rotating the rotary joint 602, the threaded rod 6 is driven to rotate, thereby driving the drive shaft 2 to move. The distance between the connection port 203 and the support frame 101 is adjusted so that the annular guide rail 401 on the rotating disk 4 and the adapter groove 301 on the disk support 3 form a sliding connection. At this time, the centrifuge tank 5 is engaged with the mounting hole 402 on the rotating disk 4 through the mounting post 501 at the bottom, so that a reliable connection is formed between the centrifuge tank 5 and the rotating disk 4. Then, the filter screen 502 is installed, and the tank cover 9 is fixed to the top of the centrifuge tank 5 by the magnet 902. By rotating the rear end of the drive shaft 2 by a motor or other equipment that can be used as a power source, the rotating disk 4 can be kept rotating on the same horizontal plane, thereby driving the centrifuge tank 5 to rotate at high speed, and thus separating the blood in the centrifuge tank 5 through centrifugation.

[0049] After the blood centrifugation operation is completed, push the bucket lid 9 diagonally upward along the strip groove. The bucket lid 9 and the magnet 902 will move towards the arc surface of the sliding guide ring. When the magnet 902 is attracted to the arc surface of the sliding guide ring, rotate the handle 1401 to make the rotating gear shaft 14 rotate, which drives the rack rod 1601 to move downward, thereby driving the first needle tube 15 and the second needle tube 16 to move downward. The lower end of the second needle tube 16 penetrates into the centrifuge bucket 5 to extract the plasma located at the top layer.

[0050] After the extracted plasma is tested, if the content meets the standard, no further steps are required, and the relevant personnel can store the plasma. If the content does not meet the standard, the sliding base 12 is moved horizontally, allowing the lid 9 to return to the top of the centrifuge tank 5, and the magnet 902 enters the placement groove 503 to fix the lid 9. Subsequently, the rotary joint 602 is rotated, the threaded rod 6 moves backward, and at the same time, the engagement of the meshing disc 601 and the meshing groove 202 drives the drive shaft 2 to move backward, causing the annular guide rail 401 to disengage from the adapter groove 301.

[0051] Using a motor or other power source, the drive shaft 2 rotates at high speed again, driving the rotating disk 4 to rotate. Since the front end of the drive shaft 2 has a connection port 203, a rotating shaft 403 is vertically installed in the connection port 203, and the rotating shaft 403 passes through the drive shaft 2 and the connecting plate 404. Under the action of strong centrifugal force, the rotating disk 4 tilts axially while rotating, causing the centrifuge tank 5 connected above to rotate in a slant-plate motion. During the slant-plate rotation of the centrifuge tank 5, the blood inside is more thoroughly centrifuged and separated, improving the separation effect and increasing the plasma concentration index to ensure qualified centrifugation separation. After this series of operations is completed, qualified plasma can be extracted using the first needle 15 and the second needle 16 by sliding the base 12.

[0052] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A mode-adjustable blood component separation device, comprising a supporting base plate (1) and a supporting frame (101), characterized in that, A swing slant disk mechanism for controlling blood component separation and a centrifugal collection mechanism for storing and collecting blood are provided on a support frame (101), and the centrifugal collection mechanism is arranged at the front end of the swing slant disk mechanism; The swing slant disk mechanism consists of a disk support (3), a threaded rod (6), a rotating disk (4), and a drive shaft (2); The drive shaft (2) penetrates through the support frame (101), a meshing guide rail (201) is arranged at the rear end of the drive shaft (2), and a connection port (203) is opened at the front end; An arc-shaped connecting plate is arranged on the bottom surface of the rotating disk (4), and the connecting plate is rotatably connected to the connection port (203); a meshing disk (601) is arranged at the rear end of the threaded rod (6), and the meshing disk (601) meshes with the meshing guide rail (201); The disk supports (3) are symmetrically arranged at both ends of the drive shaft (2); A circular ring-shaped first sliding groove (405) and a second sliding groove (406) are opened on the bottom surface of the rotating disk (4), the first sliding groove (405) is located inside the second sliding groove (406), and the two are arranged on the same horizontal plane; Sliding marbles (1001) are symmetrically arranged in the first sliding groove (405) and the second sliding groove (406), and the sliding marbles (1001) are slidably connected to the first sliding groove (405) and the second sliding groove (406); And an auxiliary spring (10) is arranged at the bottom of the sliding marble (1001), and the auxiliary spring (10) is fixedly connected to the support frame (101); The centrifugal collection mechanism consists of a centrifugal bucket (5), a bucket cover (9), a sliding guide rail ring (8), and a syringe extraction component; The centrifugal bucket (5) is concentrically arranged with the rotating disk (4), and the two are detachably connected; A centrifugal support (7) is sleeved on the top end of the centrifugal bucket (5), and a sliding guide rail ring (8) is fixedly connected to the top end of the centrifugal support (7); A bucket cover (9) and a syringe extraction component are arranged inside the sliding guide rail ring (8), and strip-shaped sliding grooves (801) are symmetrically arranged at both ends of the sliding guide rail ring (8); Both the bucket cover (9) and the syringe extraction component are slidably connected to the strip-shaped sliding grooves (801), and the bucket cover (9) and the syringe extraction component are fixedly connected.

2. The mode-adjustable blood component separation device according to claim 1, characterized in that... ； The centrifugal support (7) is an incomplete closed circular ring-shaped structure with a notch.

3. The mode-adjustable blood component separation device according to claim 1, characterized in that... ； The syringe extraction component includes a sliding base (12), a syringe support (13), a first syringe (15), a second syringe (16), and a gear shaft; The sliding base (12) is a cylindrical structure with a hole at the center, and a syringe support (13) is vertically arranged on the sliding base (12); A rotating gear shaft (14) is arranged in the middle of the syringe support (13), A first syringe (15) is arranged at the top end of the syringe support (13), the lower end of the first syringe (15) is sleeved with the second syringe (16), and the centers of the first syringe (15), the second syringe (16), and the sliding base (12) are coaxial; A rack bar (1601) is sleeved on the outer periphery of the second syringe (16), and the rack bar (1601) is perpendicular to and meshes with the rotating gear shaft (14).

4. The mode-adjustable blood component separation device according to claim 3, characterized in that... ； The syringe support (13) is in a "冂”-shaped structure.

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