A herbicidal composition containing dichloroisoxane and clodinafop-propargyl and its application

Abstract

This invention relates to the field of pesticide technology, specifically to a herbicidal composition containing dichloroisoxane and clodinafop-propargyl and its application in controlling agricultural weeds, wherein the weight ratio of dichloroisoxane to clodinafop-propargyl in the composition is 1:0.03-32. The composition can significantly reduce herbicide damage to crops and has a synergistic effect on weeds, making it an ideal herbicide.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of pesticides, in particular, to a herbicidal composition containing dichloroisoxyfluozone and clodinafop-propargyl and its application in controlling agricultural weeds. BACKGROUND

[0002] It has become a necessary measure for wheat production to control the damage of weeds in wheat field by using herbicides. However, with the increase of use time, the weeds such as Alopecurus myosuroides, Bromus japonicus, Galium aparine, Galium spurium, Veronica longifolia, Alopecurus aequalis, Alopecurus pratensis, etc. in wheat field have developed obvious resistance to traditional herbicides, resulting in a significant decrease in control effect.

[0003] Dichloroisoxyfluozone is a new isoxazoline ketone herbicide, which can be absorbed by the roots and sprouts of weeds, and transported to all parts of the plant by transpiration. By inhibiting 1-deoxy-D-xylulose 5-phosphate synthase, dichloroisoxyfluozone blocks the synthesis of carotenoids, leading to the whitening of plant leaves and the death of plants due to the inability to perform photosynthesis. Dichloroisoxyfluozone can be used to control various grass weeds and broadleaf weeds in crop fields such as wheat, corn and cotton. In wheat fields, dichloroisoxyfluozone has good control effect on weeds such as Galium aparine, Galium spurium, Galium aparine, Veronica longifolia, Alopecurus myosuroides, Alopecurus aequalis, Alopecurus pratensis, Alopecurus japonicus and Lolium multiflorum. In particular, due to its novel mechanism of action, dichloroisoxyfluozone also has good control effect on resistant weeds, and plays an important role in the control of resistant weeds in wheat fields. However, dichloroisoxyfluozone has poor safety to wheat, and can cause phytotoxicity under low temperature conditions. Therefore, it is of great significance to improve the safety of dichloroisoxyfluozone to wheat, reduce the risk of phytotoxicity, and fully exert the effect of this new herbicide with novel mechanism of action in the control of weeds in wheat fields. SUMMARY

[0004] The applicant found that the phytotoxicity of dichloroisoxyfluozone to wheat was significantly lighter when dichloroisoxyfluozone was mixed with the herbicide clodinafop-propargyl than when dichloroisoxyfluozone was used alone. On this basis, the present application provides a herbicidal composition capable of significantly reducing the phytotoxicity of dichloroisoxyfluozone to wheat, as well as a preparation thereof, which can be used to control weeds in wheat fields, reduce the risk of phytotoxicity of herbicides, and improve the control effect.

[0005] In one aspect, the present application relates to a herbicidal composition containing dichloroisoxyfluozone and clodinafop-propargyl, wherein the weight ratio of dichloroisoxyfluozone to clodinafop-propargyl is 1:0.03-32.

[0006] Preferably, the weight ratio of dichloroisoxyfluozone to clodinafop-propargyl is 1:0.05-5.

[0007] More preferably, the weight ratio of dichloroisoxyfluozone to clodinafop-propargyl is 1:0.3-3.

[0008] In another aspect, the present application relates to a herbicide containing the above-mentioned herbicidal composition of dichloroisoxyfluozone and clodinafop-propargyl.

[0009] In the herbicide described in the present application, the dichloroisonixin and clodinafop-propargyl account for 5% to 90% of the total weight, preferably 20% to 60%, and further 30% to 50%.

[0010] The herbicide described in the present application can be added with an agriculturally acceptable adjuvant and / or carrier, and processed into any pesticide-acceptable dosage form as needed, such as wettable powder, suspension concentrate, water dispersible granule, suspoemulsion, microemulsion, emulsion in water, emulsion in oil, oil miscible flowable concentrate, soluble powder, dry flowable concentrate, granule, powder, water agent, oil agent, and microcapsule flowable concentrate, among which the preferred dosage forms are wettable powder, suspension concentrate, and water dispersible granule.

[0011] The agriculturally acceptable adjuvant and / or carrier described in the present application includes but is not limited to dispersant, wetting agent, disintegrant, binder, release agent, solvent, emulsifier, co-emulsifier, stabilizer, antifoaming agent, tackifier, density regulator, pH regulator, antifreeze, preservative, penetrant, carrier, etc.

[0012] When the composition is made into wettable powder, it contains the following components and weight contents: dichloroisonixin 1% to 50%, clodinafop-propargyl 0.1% to 80%, carrier 5% to 60%, wetting agent 3% to 10%, dispersant 3% to 10%, antifoaming agent 0.1% to 3%, and filler to make up the balance.

[0013] The preparation method can be, for example, first adsorbing the dichloroisonixin technical material onto the carrier and drying, then mixing the carrier adsorbed with the dichloroisonixin technical material, the clodinafop-propargyl technical material, the wetting agent, the dispersant, the antifoaming agent, and the filler, uniformly mixing in a mixing cylinder, and then uniformly mixing after being pulverized by an air flow pulverizer.

[0014] When the composition is made into suspension concentrate, it contains the following components and weight contents: dichloroisonixin 1% to 50%, clodinafop-propargyl 0.1% to 80%, carrier 5% to 60%, dispersant 3% to 10%, tackifier 0.1% to 0.5%, antifreeze 2% to 5%, antifoaming agent 0.1% to 5%, preservative 0.1% to 1%, and deionized water to make up the balance.

[0015] The preparation method can be, for example, first adsorbing the dichloroisonixin technical material onto the carrier and drying, then mixing the carrier adsorbed with the dichloroisonixin technical material, the clodinafop-propargyl technical material, the dispersant, and part of the water by a homogenizer, adding a sand mill, performing ultrafine grinding pulverization under water cooling conditions, then adding the remaining water in which the tackifier, the antifreeze, the antifoaming agent, and the preservative are dissolved under the action of the homogenizer, and fully mixing to obtain the product.

[0016] The composition made into water dispersible granules comprises the following components and weight contents: dichloroisoxyfloxyfen 1-50%, clodinafop-propargyl 0.1-80%, carrier 5-60%, wetting agent 1-3%, dispersing agent 5-20%, binder 0.1-2%, disintegrating agent 1-5%, separating agent 0.1-2%, defoaming agent 0.1-5%, and filler to make up the balance.

[0017] The preparation method can be, for example, as follows: first, adsorb the dichloroisoxyfloxyfen technical material onto the carrier and dry, then add the carrier adsorbed with the dichloroisoxyfloxyfen technical material, the clodinafop-propargyl technical material, the wetting agent, the dispersing agent, the binder, the disintegrating agent, the separating agent, and the filler into water and grind, and then add the defoaming agent under the action of the homogenizer to obtain a slurry. The slurry is sent into a spray drying tower for spray drying, and the product is obtained after screening.

[0018] The dispersing agent can be one or more of sodium lignosulfonate, potassium lignosulfonate, ammonium lignosulfonate, naphthalene sulfonic acid formaldehyde condensate, sodium n-dibutylnaphthalenesulfonate formaldehyde condensate, sodium methyl naphthalenesulfonate formaldehyde condensate, fatty alcohol ethylene oxide adduct phosphate, alkylphenol polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, polyoxyethylene polyoxypropylene ether block copolymer, and alkylphenol polyoxyethylene phosphate.

[0019] The wetting agent can be one or more of sodium dodecylbenzenesulfonate, sodium laurylsulfate, dioctyl butanedioate sodium sulfonate, diisopropyl naphthalene sulfonate sodium, nonylphenol polyoxyethylene ether, octylphenol polyoxyethylene ether, tridecyl alcohol polyoxyethylene ether, sodium dodecyl sulfate, fatty alcohol ethoxylate, alkylphenol ethoxylate, naphthalene sulfonate, and sodium octadecyl butanedioate.

[0020] The defoaming agent can be one or more of isooctanol, isoamyl alcohol, stearic acid, lauric acid, and ethylene oxide-propylene oxide block copolymer.

[0021] The tackifier can be one or more of xanthan gum, gelatin, gum arabic, magnesium aluminum silicate, diatomite, bentonite, polyacrylate, natural polysaccharide, xanthan gum, gypsum, clay, water glass, sodium carboxymethyl starch, soluble starch, sodium carboxymethyl cellulose, hydroxyethyl cellulose, sodium alginate, and agar.

[0022] The antifreezing agent can be one or more of ethylene glycol, propylene glycol, glycerol, polyethylene glycol, sorbitol, glycerol, urea, ammonium sulfate, glycerol-ethyl ether diethylene glycol, and methyl propylene glycol.

[0023] The preservative can be one or more of formaldehyde, sodium salicylate, sodium benzoate, 1,2-benzothiazolin-3-one, 2-hydroxydiphenyl, sorbic acid, benzoic acid, benzaldehyde, p-hydroxybenzaldehyde, and p-hydroxybenzyl ester.

[0024] The disintegrant can be one or more of thiamine, calcium chloride, aluminum chloride;

[0025] The binder can be one or more of polyvinyl acetate polymer, polyvinyl alcohol, ethylene-vinyl acetate copolymer, soluble starch;

[0026] The release agent can be one or more of amorphous silica gel, fumed silica gel;

[0027] The carrier and / or filler can be one or more of white carbon black, bentonite, kaolin, activated white clay, attapulgite, diatomite, light calcium carbonate, talc, lepidolite, clay;

[0028] The third aspect of the present application relates to the use of the above-mentioned herbicidal composition and / or herbicide in the control of agricultural weeds.

[0029] Preferably, the herbicidal composition and / or herbicide is used for controlling weeds in wheat fields, such as tall oat grass, common bentgrass, Japanese bentgrass, blackgrass, false oat, brome, loose silky-jointweed, silphium, shepherd's-purse, corncockle, cornflower, etc.

[0030] More preferably, the herbicidal composition and / or herbicide is used for controlling tall oat grass in wheat fields.

[0031] Further, the herbicidal composition or herbicide of the present application reduces phytotoxicity to crops when used in the control of agricultural weeds. Tests show that the phytotoxicity of dichloroisonixarone mixed with herbicide cloquintocet-mexyl to wheat is significantly lighter than that of dichloroisonixarone alone.

[0032] In the application described in the present application, the effective component of the herbicidal composition and / or herbicide has a field use amount of 30-1200 g / hm 2 , preferably 100-900 g / hm 2 , and more preferably 200-600 g / hm 2 .

[0033] The use method of the herbicidal composition or herbicide described in the present application includes but is not limited to making a mixed preparation, using in a bucket, or adding other effective components or adjuvants.

[0034] The present application has the following positive beneficial effects:

[0035] 1. After dichloroisonixarone and cloquintocet-mexyl are compounded, the phytotoxicity to crops is significantly lighter than that of dichloroisonixarone alone;

[0036] 2. After dichloroisonixarone and cloquintocet-mexyl are compounded, the weeds have a significant synergistic effect, and have good control effect on resistant weeds;

[0037] 3. Dichloroisoxane and clodinafop-propargyl have different mechanisms of action, and their combined use can delay the development of herbicide resistance in weeds. Attached Figure Description

[0038] Figure 1 This figure shows the phytotoxicity of wheat caused by dichlorvos alone. As can be seen from the figure, 216 g ai / hm of 36% dichlorvos suspension concentrate... 2 After treatment, the wheat heart leaves were severely whitened and yellowed, the growing point was severely inhibited, the wheat growth was severely affected, and the overall pesticide damage was severe and difficult to recover.

[0039] Figure 2 This figure shows the phytotoxicity of the herbicidal composition of the present invention on wheat. As can be seen from the figure, the dosage in Formulation Example 6 was 351 g a.i. / hm. 2 (Dichloroisoxane dosage 216g ai / hm) 2 After treatment, the wheat leaves showed slight yellowing, but the growing points were not significantly affected. Overall, the pesticide damage was minor and the plant was able to recover. Detailed Implementation

[0040] The following embodiments are used to illustrate the present invention, but are not intended to limit the scope of the invention. Where specific techniques or conditions are not specified in the embodiments, they should be performed in accordance with the techniques or conditions described in the literature in the field, or in accordance with the product instructions. Unless otherwise specified, all percentage contents in all embodiments of the present invention refer to weight percentage contents.

[0041] (I) Formulation Examples

[0042] Formulation Example 1: 20% dichloroisoxane·clodinafop-propargyl wettable powder

[0043] Dichloroisoxane 19.4%, clodinafop-propargyl 0.6%, silica 25%, coagulant 3%, ammonium lignosulfonate 4%, isooctyl alcohol 0.2%, bentonite to make up the balance.

[0044] First, the technical grade dichlorvos is uniformly adsorbed onto silica and dried. Then, silica with adsorbed dichlorvos, clodinafop-propargyl technical grade, clethodim, ammonium lignosulfonate, isooctyl alcohol, and bentonite are mixed and homogenized in a mixing tank. After being pulverized by an air jet mill, they are mixed evenly again.

[0045] Formulation Example 2: 20% dichloroisoxane·clodinafop-propargyl suspension

[0046] Dichloroisoxane 19%, clodinafop-propargyl 1%, silica 25%, alkylphenol polyoxyethylene ether phosphate 3%, polyoxyethylene polyoxypropylene ether block copolymer 3%, polyacrylate 0.1%, ethylene glycol 4%, lauric acid 1%, 2-hydroxybiphenyl 0.5%, deionized water to make up the balance.

[0047] First, the dichloroisonixin technical material is uniformly adsorbed onto white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the alkylphenol polyoxyethylene ether phosphate, the polyoxyethylene polyoxypropylene ether block copolymer, and part of the water are coarsely mixed by a homogenizer, then added into a sand mill, and ultra-micro ground and crushed under water cooling, then the remaining water in which polyacrylate, ethylene glycol, lauric acid, and 2-hydroxydiphenyl are dissolved is added under the action of the homogenizer, and thoroughly mixed to form the product. Preparation Example 3: 30% dichloroisonixin-fluazifop-butyl water dispersible granules

[0048] Dichloroisonixin 27.2%, fluazifop-butyl 2.8%, white carbon black 35%, alkylphenol ethoxylate 2%, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate 3%, alkylphenol polyoxyethylene phosphate 3%, polyvinyl acetate polymer 0.5%, thiamine 1.5%, aerosol silica 0.5%, isoamyl alcohol 0.5%, and diatomite to make up the balance.

[0049] First, the dichloroisonixin technical material is uniformly adsorbed onto white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, the alkylphenol polyoxyethylene phosphate, the polyvinyl acetate polymer, the thiamine, the aerosol silica, and the diatomite are ground in water, then isoamyl alcohol is added under the action of the homogenizer to obtain a slurry. The slurry is sprayed and dried in a drying tower, sieved, and the product is obtained. Preparation Example 4: 30% dichloroisonixin-fluazifop-butyl wettable powder

[0050] Dichloroisonixin 22.9%, fluazifop-butyl 7.1%, white carbon black 30%, sodium dodecylbenzenesulfonate 4%, sodium lignosulfonate 4%, isoamyl alcohol 0.3%, and kaolin to make up the balance.

[0051] First, the dichloroisonixin technical material is uniformly adsorbed onto white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the sodium dodecylbenzenesulfonate, the sodium lignosulfonate, and the isoamyl alcohol are mixed and uniformly mixed in a mixing cylinder, and then uniformly mixed after being crushed by an air flow crusher.

[0052] Preparation Example 5: 30% dichloroisonixin-fluazifop-butyl suspension concentrate

[0053] Dichloroisonixin 21.2%, fluazifop-butyl 8.8%, white carbon black 25%, fatty alcohol ethylene oxide adduct phosphate 4%, alkylphenol polyoxyethylene phosphate 4%, hydroxyethyl cellulose 0.5%, propylene glycol 2%, stearic acid 2%, sodium benzoate 0.5%, and deionized water to make up the balance.

[0054] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the fatty alcohol ethylene oxide adduct phosphoric acid salt, the alkylphenol polyoxyethylene ether phosphoric acid ester, and part of the water are coarsely mixed by a homogenizer, then added into a sand mill, and ultra-micro ground and crushed under water cooling, then the remaining water in which the hydroxyethyl cellulose, the propylene glycol, the stearic acid, and the sodium benzoate are dissolved is added under the action of the homogenizer, and thoroughly mixed to obtain the product.

[0055] Preparation Example 6: 40% dichloroisonixin·fluazifop-butyl water dispersible granules

[0056] Dichloroisonixin 24.6%, fluazifop-butyl 15.4%, white carbon black 30%, sodium octadecyl succinate 2%, naphthalene sulfonic acid sodium formaldehyde condensate 4%, polyoxyethylene polyoxypropylene ether block copolymer 4%, ethylene-vinyl acetate copolymer 1%, aluminum chloride 2%, amorphous silica gel 1%, lauric acid 1%, and light calcium carbonate to make up the balance.

[0057] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the sodium octadecyl succinate, the naphthalene sulfonic acid sodium formaldehyde condensate, the polyoxyethylene polyoxypropylene ether block copolymer, the ethylene-vinyl acetate copolymer, the aluminum chloride, the amorphous silica gel, and the light calcium carbonate are ground in water, then the lauric acid is added under the action of the homogenizer to obtain a slurry. The slurry is sent into a spray drying tower for spray drying, sieved, and then the product is obtained.

[0058] Dichloroisonixin 19.5%, fluazifop-butyl 30.5%, white carbon black 25%, sodium dodecyl sulfate 5%, potassium lignosulfonate 5%, stearic acid 0.5%, and active white clay to make up the balance.

[0059] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the sodium dodecyl sulfate, the potassium lignosulfonate, the stearic acid, and the active white clay are mixed and uniformly mixed in a mixing cylinder, and then uniformly mixed after being crushed by an air flow crusher.

[0060] Preparation Example 8: 40% dichloroisonixin·fluazifop-butyl suspension concentrate

[0061] Dichloroisonixin 13%, fluazifop-butyl 27%, white carbon black 20%, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate 3%, polyoxyethylene polyoxypropylene ether block copolymer 3%, sodium carboxymethyl cellulose 0.2%, sorbitol 3%, isopentyl alcohol 1.5%, p-hydroxybenzaldehyde 0.5%, and deionized water to make up the balance.

[0062] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, the polyoxyethylene polyoxypropylene ether block copolymer, and part of the water are coarsely mixed by a homogenizer, then added into a sand mill, and ultra-micro ground and crushed under water cooling, then the remaining water in which the sodium carboxymethyl cellulose, sorbitol, isoamyl alcohol, and p-hydroxybenzaldehyde are dissolved is added under the action of the homogenizer, and thoroughly mixed to obtain the product.

[0063] Preparation Example 9: 50% dichloroisonixin·fluazifop-butyl water dispersible granules

[0064] Dichloroisonixin 9.7%, fluazifop-butyl 40.3%, white carbon black 15%, sodium dodecyl sulfate 2%, alkylphenol polyoxyethylene ether phosphate 5%, polyoxyethylene polyoxypropylene ether block copolymer 5%, polyvinyl alcohol 1.5%, calcium chloride 3%, amorphous silica gel 1.5%, iso-octanol 1%, bentonite to make up the balance.

[0065] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the sodium dodecyl sulfate, the alkylphenol polyoxyethylene ether phosphate, the polyoxyethylene polyoxypropylene ether block copolymer, the polyvinyl alcohol, the calcium chloride, the amorphous silica gel, and the bentonite are ground in water, then iso-octanol is added under the action of the homogenizer to obtain a slurry. The slurry is sent into a drying tower for spray drying, sieved, and then the product is obtained.

[0066] Preparation Example 10: 60% dichloroisonixin·fluazifop-butyl wettable powder

[0067] Dichloroisonixin 3.6%, fluazifop-butyl 56.4%, white carbon black 8%, sodium diisopropyl naphthalene sulfonate 6%, naphthalene sulfonate formaldehyde condensate 6%, isoamyl alcohol 1%, light calcium carbonate to make up the balance.

[0068] First, the dichloroisonixin technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloroisonixin technical material, the fluazifop-butyl technical material, the sodium diisopropyl naphthalene sulfonate, the naphthalene sulfonate formaldehyde condensate, the isoamyl alcohol, and the light calcium carbonate are mixed, uniformly mixed in a mixing cylinder, and then uniformly mixed after being crushed by an air flow crusher.

[0069] Preparation Example 11: 50% dichloroisonixin·fluazifop-butyl suspension concentrate

[0070] Dichloroisonixin 1.6%, fluazifop-butyl 48.4%, white carbon black 5%, sodium methyl naphthalene sulfonate formaldehyde condensate 5%, alkylphenol polyoxyethylene ether phosphate 5%, magnesium aluminum silicate 0.4%, ammonium sulfate 2.5%, iso-octanol 2.5%, sodium salicylate 0.5%, deionized water to make up the balance.

[0071] First, the dichloro isoxadifen-ethyl technical material is uniformly adsorbed onto the white carbon black and dried, then the white carbon black adsorbed with the dichloro isoxadifen-ethyl technical material, the fluazifop-butyl technical material, the sodium methyl naphthalene sulfonate formaldehyde condensate, the alkyl phenol polyoxyethylene phosphoric acid ester, and part of the water are coarsely mixed by a homogenizer, then added into a sand mill, and ultra-micro ground and crushed under water cooling, and then the rest of the water in which magnesium aluminum silicate, ammonium sulfate, isooctanol, and sodium salicylate are dissolved is added into the homogenizer and mixed thoroughly.

[0072] (B) Indoor bioassay examples

[0073] The indoor bioassay examples of the present application are carried out according to the Guidelines of Pesticide Indoor Bioassay Test Herbicide Part 7: Determination of Combined Action of Mixtures (NY / T 1155.7-2006), and the combined action of two kinds of pesticides mixed in a certain proportion on crops and weeds is determined through indoor bioassay. The test method is as follows:

[0074] Accurately weigh 5.21 g of 96% dichloro isoxadifen-ethyl technical material, dissolve in 100 mL of petroleum ether, and prepare a dichloro isoxadifen-ethyl mother liquor with a concentration of 50 g / L. Accurately weigh 5.26 g of 95% fluazifop-butyl technical material, dissolve in 100 mL of N,N-dimethylformamide: xylene = 1:5 (w / w), and prepare a fluazifop-butyl mother liquor with a concentration of 50 g / L. During the test, appropriate amounts of dichloro isoxadifen-ethyl mother liquor and fluazifop-butyl mother liquor are diluted with appropriate amounts of 0.1% Tween 80 aqueous solution to prepare the test solutions.

[0075] A pot test method is used, and the test targets are wheat and the main weeds in wheat fields, Alopecurus carolinianus. In a sunlight greenhouse, plastic pots with a diameter of 12 cm and a height of 11 cm are used for seedling culture, and the seedlings are fixed before spraying, with 10 uniform wheat or weed plants per pot. Stem and leaf spraying treatment is carried out at the 3-4 leaf stage, with 8 replicates per treatment, and the amount of liquid is 450 L / hm 2 . After 14 days, the fresh weight of the aboveground part of each pot is weighed, and the actual phytotoxicity rate / efficacy E of each treatment is calculated.

[0076]

[0077] PT——fresh weight of the phytotoxicity treatment group;

[0078] CK——fresh weight of the blank control group.

[0079] The combined action of the two kinds of pesticides mixed in a certain proportion on wheat or weeds is evaluated by the Gowing method, and the theoretical phytotoxicity rate / efficacy E0 of the mixture is calculated by the following formula:

[0080]

[0081] X——the phytotoxicity rate / efficacy of herbicide A at a dosage of P;

[0082] Y – Herbicide damage rate / control efficacy when herbicide B is applied at a dosage of Q;

[0083] E0 – The theoretical phytotoxicity rate / control efficacy after mixing herbicide A at dosage P and herbicide B at dosage Q;

[0084] E – Actual phytotoxicity / control efficacy after mixing herbicide A (at dosage P) and herbicide B (at dosage Q).

[0085] E-E0 > 10% indicates a synergistic effect; E-E0 < -10% indicates an antagonistic effect; -10% < E-E0 < 10% indicates an additive effect.

[0086] Indoor bioassay example 1:

[0087] The target crop was wheat (Jimai 22 variety). The dosage and efficacy of each herbicide treatment are shown in Table 1. Biochemical tests showed that when the ratio of dichlorvos to clodinafop-propargyl was between 1:0.03 and 32, the E-E0 value was -18.7% to -10.5%, indicating that the mixture of the two herbicides within this range had a significant antagonistic effect on wheat herbicide damage and could significantly reduce the damage. When the ratio of dichlorvos to clodinafop-propargyl was between 1:0.05 and 5, the E-E0 value was -18.7% to -13.2%, indicating that the antagonistic effect on wheat herbicide damage was more pronounced within this range. When the ratio of dichlorvos to clodinafop-propargyl was between 1:0.3 and 3, the E-E0 value was -18.7% to -15.9%, indicating that the antagonistic effect on wheat herbicide damage was most significant within this range.

[0088] Table 1. Results of bioassays on wheat using different ratios of dichloroisoxane and clodinafop-propargyl.

[0089]

[0090]

[0091] Indoor bioassay example 2:

[0092] The target species tested was *Alopecurus aequalis*, and the dosage and efficacy of each treatment are shown in Table 2. Biochemical tests showed that when the ratio of dichlorvos to clodinafop-propargyl was between 1:0.03 and 32, the E-E0 value was 10.4%–17.6%, indicating that the mixture of the two herbicides within this range had a significant synergistic effect on *Alopecurus aequalis*. When the ratio of dichlorvos to clodinafop-propargyl was between 1:0.05 and 5, the E-E0 value was 12.4%–17.6%, indicating that the synergistic effect was even more pronounced when the mixture was within this range. When the ratio of dichlorvos to clodinafop-propargyl was between 1:0.3 and 3, the E-E0 value was 15.1%–17.6%, indicating that the synergistic effect was most significant when the mixture was within this range.

[0093] Table 2. Results of the effects of different ratios of dichloroisoxane and clodinafop-propargyl on the growth of *Alopecurus aequalis*.

[0094]

[0095]

[0096] (III) Examples of Field Efficacy Trials

[0097] The field efficacy test examples of this invention were conducted in accordance with the "Guidelines for Field Efficacy Tests of Pesticides (I) Herbicides for Weed Control in Wheat Crops (GB / T 17980.41-2000)". Field plot trials were used to verify the results of indoor bioassays and to clarify the effect of the two agents, when combined in a certain proportion, on reducing phytotoxicity to wheat and their field control effect on weeds. The test methods are as follows:

[0098] Foliar spraying at the 3-5 leaf stage after winter wheat sowing (mid-November), with a solution volume of 450 L / hm². 2 Each treatment was repeated four times, with a plot size of 125 m², arranged in a randomized block design. A survey was conducted 15 days post-treatment. Four sampling points were randomly selected from each plot to investigate the aboveground fresh weight of all wheat seedlings or all weeds within each sampling point. Each wheat sampling point was 0.25 m². 2 Each weed sampling point is 1m in size. 2 Calculate the actual phytotoxicity rate / control efficacy E for each treatment:

[0099]

[0100] In the formula: PT—fresh weight of wheat / weeds in the treated area;

[0101] CK – Fresh weight of wheat / weeds in the blank control area.

[0102] The data obtained from the survey, referencing the "Guidelines for Indoor Bioassay Testing of Pesticides - Herbicides Part 7: Determination of Combined Effects of Mixed Herbicides (NY / T 1155.7—2006)," used the Gowing method to evaluate the combined effects of two herbicides mixed in a certain proportion on wheat or weeds. The formula for calculating the theoretical phytotoxicity rate / control efficacy E0 after mixing is as follows:

[0103]

[0104] In the formula: X — phytotoxicity rate / control efficacy when herbicide A is applied at a dosage of P;

[0105] Y – Herbicide damage rate / control efficacy when herbicide B is applied at a dosage of Q;

[0106] E0 – The theoretical phytotoxicity rate / control efficacy after mixing herbicide A at dosage P and herbicide B at dosage Q;

[0107] E – Actual phytotoxicity / control efficacy after mixing herbicide A (at dosage P) and herbicide B (at dosage Q).

[0108] E-E0 > 10% indicates a synergistic effect; E-E0 < -10% indicates an antagonistic effect; -10% < E-E0 < 10% indicates an additive effect.

[0109] The experiment was conducted in Wagu Village, Nanhe District, Xingtai City, Hebei Province. The wheat variety was Tianci Mai No. 1, and the main weed in the field was large-eared wheatgrass, which was evenly distributed.

[0110] Table 3 shows the dosage of each pesticide and the rate of phytotoxicity to wheat. Field trial results showed that the effective dosage of dichloroisoxane was 162 g / hm². 2 The phytotoxicity rate of dichloroisoxane single agent to wheat was 19.4%, while the phytotoxicity rate of the composition described in this invention to wheat was 4.0%–8.2%, with an E-E0 value of -15.7%–-15.4%; the effective dosage of dichloroisoxane was 216 g / hm². 2 The phytotoxicity rate of dichloroisoxane single agent to wheat was 24.7%, while the phytotoxicity rate of the composition described in this invention was 7.4%–9.8%, with an E-E0 value of -19.6%–-14.9%. Compared with dichloroisoxane single agent, the dichloroisoxane and clodinafop-propargyl composition of this invention significantly reduces the phytotoxicity rate to wheat under the same dosage of dichloroisoxane active ingredient. This indicates that in practical applications, the composition of this invention has a significant antagonistic effect on wheat phytotoxicity and can significantly reduce the phytotoxicity caused by dichloroisoxane single agent to wheat.

[0111] Table 3. Results of field trials on wheat herbicide damage caused by the combined use of dichloroisoxane and clodinafop-propargyl.

[0112]

[0113] Table 4 shows the dosage of each treatment agent and its efficacy against weeds in wheat fields. Field trial results show that the E-E0 value of the dichloroisoxane and clodinafop-propargyl combination described in this invention is 12.8% to 16.7% for the control of wheatgrass, indicating that the combination described in this invention has a significant synergistic effect on weeds in wheat fields in practical applications.

[0114] Table 4. Field efficacy test results of dichloroisoxane and clodinafop-propargyl against weeds in wheat fields.

[0115]

[0116] Therefore, the dichloroisoxane and clodinafop-propargyl composition of the present invention, without the need for the addition of a safener, can significantly reduce phytotoxicity to crops and improve weed control efficacy by virtue of their unique interaction mechanism and their interaction mechanism with crops or weeds, making it an ideal herbicide.

[0117] This invention has been described through specific embodiments. Those skilled in the art can refer to the content of this invention and appropriately modify the raw materials, process conditions, and other aspects to achieve other corresponding objectives. Such modifications do not depart from the content of this invention, and all similar substitutions and alterations are considered to be included within the scope of this invention, as they do not depart from the spirit of this invention.

Claims

1. A herbicidal composition comprising dichloroisonixoxime and clodinafop-propargyl, characterized in that, The weight ratio of dichloroisonixappontane and clodinafop-propargyl is 1:0.03-0.31, or 1:0.42-32.

2. The herbicidal composition according to claim 1, characterized by The weight ratio of dichloroisonixappontane and clodinafop-propargyl is 1:0.05-0.31, or 1:0.42-5.

3. The herbicidal composition according to any one of claims 1 or 2, characterized in that, The weight ratio of dichloroisonixappontane and clodinafop-propargyl is 1:0.42-3.

4. A herbicide containing the herbicidal composition according to any one of claims 1-3.

5. The herbicide according to claim 4, characterized in that, The dichloroisonixappontane and clodinafop-propargyl account for 5%-90% of the total weight.

6. The herbicide according to any one of claims 4 or 5, characterized in that, The herbicidal composition is prepared into any pesticide-acceptable dosage form selected from wettable powder, suspension concentrate, water dispersible granule, suspoemulsion, microemulsion, emulsion in water, emulsion in oil, oil miscible flowable concentrate, soluble powder, dry flowable concentrate, granule, powder, water, and microcapsule suspension concentrate.

7. Use of the herbicidal composition according to any one of claims 1-3 or the herbicide according to any one of claims 4-6 in controlling agricultural weeds and / or reducing the phytotoxicity of dichloroisonixappontane to wheat.

8. Use according to claim 7, characterized in that, The herbicidal composition or herbicide is used for controlling weeds in wheat field.

9. The use according to any one of claims 7 or 8, characterized in that, The weeds include: tall oat grass, common bentgrass, Japanese bentgrass, blackgrass, false oat, brome, rye-grass, shepherd's-purse, shepherd's-purse, cornflower, and cornflower. The weeds include: tall oat grass, common bentgrass, Japanese bentgrass, blackgrass, false oat, brome, rye-grass, shepherd's-purse, shepherd's-purse, cornflower, and cornflower.

10. Use according to any one of claims 7 or 8, characterized in that, The effective component of the herbicidal composition or herbicide is used in an amount of 30-1200 g / hm 2 .

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