Peripheral artery stent

Abstract

The present invention provides a peripheral artery stent, which relates to the field of medical devices, and includes a plurality of groups of support rod components and a plurality of groups of connecting rod components. The plurality of groups of support rod components are arranged in sequence from the proximal end to the distal end. The support rod components include a plurality of groups of support rod units connected in sequence along the circumferential direction. The support rod unit includes a first support portion and a second support portion that are symmetrically arranged. The angle between the first support portion and the second support portion gradually increases from the proximal end to the distal end. By gradually increasing the angle between the first support portion and the second support portion from the proximal end to the distal end, on the one hand, the length of the first support portion and the second support portion is increased, and the first support portion and the second support portion are extended along the tangent function curve, thereby enhancing the flexibility of the peripheral artery stent in the axial and radial directions; on the other hand, the contact surface between the support rod component and the blood vessel wall is increased, the unit stress borne by the blood vessel wall is reduced, the support rod is prevented from breaking, and the occurrence of vascular intimal hyperplasia is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a peripheral artery stent. Background Art

[0002] Peripheral arteries help transport blood rich in oxygen and various nutrients to various parts of the body. When peripheral arteries are narrowed, various parts of the body cannot get enough blood or oxygen, and the human body will experience adverse symptoms including limb movement disorders, speech disorders, pain, stroke, etc. Peripheral artery stenosis or even occlusion refers to a pathological state in which the inner diameter of the peripheral arteries becomes narrower, resulting in obstructed blood circulation. This may be caused by a variety of reasons such as atherosclerosis, large artery inflammation, and vascular damage. Peripheral artery stenosis may occur in different parts of the body, such as the carotid arteries, limb arteries, etc. The severity and symptoms vary from individual to individual. Arterial calcification and atherosclerosis are the main factors leading to vascular stenosis or occlusion.

[0003] The main treatment method at present is to implant a permanent tubular stent at the lesion site to support the narrowed blood vessels and restore blood flow. The main structure of traditional stents on the market is a long tubular shape. The tube part is composed of continuous struts. In order to provide sufficient support strength, the struts are designed to be "connected in pairs" to form a "dense network" structure. This structure with closely connected struts cannot provide good flexibility when the blood vessels are bent, compressed, stretched, etc., and has a high potential risk of fracture and deformation, which will eventually damage the blood vessels or organs. In addition, traditional stents provide too much external expansion force, which leads to severe intimal hyperplasia and re-stenosis of the blood vessels. Summary of the invention

[0004] The invention provides a peripheral artery stent, which is used to solve the problem that the existing stent has a large external expansion force and is easy to cause large intimal hyperplasia.

[0005] The present invention provides a peripheral artery stent, comprising:

[0006] A plurality of groups of support rod components, wherein the plurality of groups of support rod components are arranged in sequence from the proximal end to the distal end, the support rod components include a plurality of groups of support rod units connected in sequence along the circumferential direction, the support rod units include a first support portion and a second support portion symmetrically arranged, and the angle between the first support portion and the second support portion gradually increases from the proximal end to the distal end; in each group of support rod units, the first end of the first support portion is connected to the first end of the second support portion to form a trough; in two adjacent groups of support rod units, the second end of one group of the first support portions is connected to the second end of the other group of the second support portions to form a peak;

[0007] A plurality of groups of connecting rod components are arranged one-to-one between two adjacent groups of supporting rod components.

[0008] According to a peripheral artery stent provided by an embodiment of the present invention, the first supporting portion and the second supporting portion both extend along a tangent function curve.

[0009] According to a peripheral artery stent provided by an embodiment of the present invention, the connecting rod component includes:

[0010] A plurality of connecting rod bodies are arranged evenly spaced along the circumferential direction, the connecting rod bodies extend along a tangent function curve, one end of the connecting rod body is connected to the crest of one group of the support rod parts in two adjacent groups of the support rod parts, and the other end of the connecting rod body is connected to the trough of the other group of the support rod parts.

[0011] According to a peripheral artery stent provided by an embodiment of the present invention, the wave crests of one group of the support rod components in two adjacent groups of the support rod components are arranged alternately with the wave troughs of the other group of the support rod components.

[0012] According to a peripheral artery stent provided by an embodiment of the present invention, the peripheral artery stent is tapered, and the cross-sectional area of ​​the proximal end of the peripheral artery stent is larger than the cross-sectional area of ​​the distal end of the peripheral artery stent.

[0013] According to a peripheral artery stent provided by an embodiment of the present invention, the length of the peripheral artery stent is 20-200 mm, the taper of the peripheral artery stent is 0.02-0.05, and the diameter of the proximal end of the peripheral artery stent is 3-10 mm.

[0014] According to a peripheral artery stent provided by an embodiment of the present invention, the number of support rod units in each group of support rod components is equal.

[0015] According to a peripheral artery stent provided by an embodiment of the present invention, at least one crest of the support rod component at the distal end and at least one trough of the support rod component at the proximal end are respectively provided with a developing ring, and the developing ring is provided with a developing point.

[0016] According to a peripheral artery stent provided by an embodiment of the present invention, the surface of the peripheral artery stent is coated with an anticoagulant coating.

[0017] In a peripheral artery stent provided according to an embodiment of the present invention, the anticoagulant coating is a combination of one or more of a heparin coating, a phosphorylcholine coating, a polypeptide coating, and a nano coating.

[0018] The peripheral artery stent provided by the embodiment of the present invention gradually increases the angle between the first support portion and the second support portion in the direction from the proximal end to the distal end. On the one hand, the lengths of the first support portion and the second support portion are increased, and the first support portion and the second support portion both extend along the tangent function curve, thereby enhancing the flexibility of the peripheral artery stent in the axial and radial directions; on the other hand, the contact area between the support rod component and the blood vessel wall is increased, thereby reducing the unit stress borne by the blood vessel wall, preventing the support rod from breaking, and avoiding the occurrence of vascular intimal hyperplasia. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 is a schematic side view of the structure of a peripheral artery stent provided by an embodiment of the present invention;

[0021] Figure 2 is a schematic structural diagram of a peripheral artery stent provided by an embodiment of the present invention in an expanded state;

[0022] Figure 3 yes Figure 2 A schematic diagram of the local enlarged structure at point A in the middle;

[0023] Figure 4 yes Figure 2 A schematic diagram of the local enlarged structure at B in the middle;

[0024] Figure 5 yes Figure 2 A schematic diagram of the local enlarged structure at C in the middle;

[0025] Figure 6 is a schematic diagram of a partial structure of a peripheral artery stent provided by an embodiment of the present invention in an expanded state;

[0026] Figure 7 It is a schematic diagram of the use principle of the peripheral artery stent provided by an embodiment of the present invention.

[0027] Reference numerals:

[0028] 10. Support rod component; 11. Support rod unit; 13. Developing ring; 14. Developing point;

[0029] 20. Connecting rod component; 21. Connecting rod body;

[0030] 111. First supporting portion; 112. Second supporting portion; 113. Wave trough; 114. Wave peak; 30. Diseased blood vessel. DETAILED DESCRIPTION

[0031] The following embodiments of the present invention are described in further detail in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0032] In the description of the embodiments of the present invention, it should be noted that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the embodiments of the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limitations on the embodiments of the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0033] In the description of the embodiments of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the embodiments of the present invention can be understood according to specific circumstances.

[0034] In the embodiments of the present invention, unless otherwise clearly specified and limited, the first feature being "above" or "below" the second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0035] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the embodiment of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0036] Combine the following Figure 1-Figure 7 A peripheral artery stent according to an embodiment of the present invention is described.

[0037] Figure 1 The side view schematic diagram of the peripheral artery stent provided by the embodiment of the present invention is illustrated. Figure 2 The schematic diagram of the structure of the peripheral artery stent provided by the embodiment of the present invention in the expanded state is illustrated. Figure 3 yes Figure 2 The local enlarged structural diagram at A in the figure is as follows: Figures 1 to 3 As shown, the peripheral artery stent includes multiple groups of support rod components 10 and multiple groups of connecting rod components 20, the multiple groups of support rod components 10 are arranged in sequence from the proximal end to the distal end, the support rod components 10 include multiple groups of support rod units 11 connected in sequence along the circumferential direction, the support rod unit 11 includes a symmetrically arranged first support portion 111 and a second support portion 112, and the angle between the first support portion 111 and the second support portion 112 gradually increases from the proximal end to the distal end; in each group of support rod units 11, the first end of the first support portion 111 is connected to the first end of the second support portion 112 to form a trough 113; in two adjacent groups of support rod units 11, the second end of one group of the first support portion 111 is connected to the second end of the other group of the second support portion 112 to form a peak 114. Multiple groups of connecting rod components 20 are arranged between two adjacent groups of support rod components 10 in a one-to-one correspondence.

[0038] The peripheral artery stent provided in the embodiment of the present invention gradually increases the angle between the first support portion 111 and the second support portion 112 from the proximal end to the distal end. On the one hand, the length of the first support portion 111 and the second support portion 112 is increased, and the first support portion and the second support portion both extend along the tangent function curve, thereby enhancing the flexibility of the peripheral artery stent in the axial and radial directions; on the other hand, the contact area between the support rod component and the blood vessel wall is increased, thereby reducing the unit stress borne by the blood vessel wall, preventing the support rod from breaking, and avoiding the occurrence of vascular intimal hyperplasia.

[0039] In one embodiment of the present invention, the first support portion 111 and the second support portion 112 both extend along the tangent function curve, that is, the center line of the first support portion 111 and the center line of the second support portion 112 coincide with the corresponding tangent function curve, and the tangent line ( Figure 3 The dotted line in the figure is the tangent line) and its slope first decreases and then increases in the direction from the proximal end to the distal end. This tangent function curve support portion can follow the torsion direction when the stent is torsioned in the radial and axial directions, thereby improving the flexibility in the radial direction.

[0040] In a preferred embodiment of the present invention, Figure 3 As shown, the tangent line of the first end of the first support part 111 and the tangent line of the first end of the second support part 112 are both parallel to the axis of the peripheral artery stent. Similarly, the tangent line of the second end of the first support part 111 and the tangent line of the second end of the second support part 112 are both parallel to the axis of the peripheral artery stent.

[0041] In a preferred embodiment of the present invention, Figure 3 As shown, the angle between the first support portion 111 and the second support portion 112 is smaller at the proximal end, and the distance between the first support portion 111 and the second support portion 112 is smaller, so as to improve the support strength of the peripheral artery stent in the radial direction. As the opening angle increases, the distance between the first support portion 111 and the second support portion 112 gradually increases. Here, the distance between the first support portion 111 and the second support portion 112 is denoted as L1, and the value range of L1 is 0.8-1.8mm. The width of the first support portion 111 and the second support portion 112 is denoted as W1, and preferably, the value range of W1 is 0.08-0.12mm. The distance between the crest 114 and the trough 113 in the same group of support rod components 10 is denoted as H1, and preferably, the value range of H1 is 1.0-1.8mm.

[0042] In one embodiment of the present invention, Figure 2 As shown, each group of support rod components 10 has an equal number of support rod units 11, and each group of support rod components 10 has 8-18 support rod units 11. Of course, the number of support rod units 11 in each group is not limited thereto, and a larger number of support rod units 11 may also be provided, which is specifically determined according to the width of the support rod unit 11 and the size of the peripheral artery stent.

[0043] In one embodiment of the present invention, Figure 1 and Figure 2 As shown, the peripheral artery stent is tapered, and the cross-sectional area of ​​the proximal end of the peripheral artery stent is larger than the cross-sectional area of ​​the distal end of the peripheral artery stent. Since the inner diameter of the distal end of the blood vessel is slightly smaller than the inner diameter of the proximal end, by setting the peripheral artery stent in a tapered shape, the peripheral artery stent can better fit the inner wall of the blood vessel, increase the contact area with the inner wall of the blood vessel, and avoid damaging the blood vessel.

[0044] The widths of the support rod units 11 in each group of support rod components 10 are equal to facilitate processing thereof. In order to make the peripheral artery stent tapered, the opening angle of the support rod units 11 from the proximal end to the distal end is gradually reduced, ensuring that the peripheral artery stent is tapered when the number of support rod units 11 in each group of support rod components 10 is equal, and at the same time, the radial support strength per unit area of ​​the distal end of the stent can be improved.

[0045] In one embodiment of the present invention, the length of the peripheral artery stent is 20-200 mm, the taper of the peripheral artery stent is 0.02-0.05, and the diameter of the proximal end of the peripheral artery stent is 3-10 mm.

[0046] In one embodiment of the present invention, Figure 5 yes Figure 2 The schematic diagram of the local enlarged structure at C in the middle, Figure 6 FIG. 4 is a schematic diagram of a partial structure of a peripheral artery stent provided by an embodiment of the present invention in an expanded state; Figure 5 and Figure 6 As shown, the connecting rod component 20 includes a plurality of connecting rod bodies 21, which are arranged at intervals along the circumferential direction, and the connecting rod bodies 21 are used to connect two adjacent groups of support rod components 10 together to improve the structural strength of the peripheral artery stent. One end of the connecting rod body 21 is connected to the crest 114 of one group of support rod components 10 in the two adjacent groups of support rod components 10. Specifically, one end of the connecting rod body 21 is integrally formed with the crest 114 of one group of support rod components 10 in the two adjacent groups of support rod components 10. In this case, the peripheral artery stent is manufactured by laser cutting technology.

[0047] In one embodiment of the present invention, each group of connecting rod components 20 has the same number of connecting rod bodies 21 , and each group of connecting rod components 20 is provided with 3-6 connecting rod bodies 21 . In this embodiment, each group of connecting rod components 20 is provided with 3 connecting rod bodies 21 .

[0048] In one embodiment of the present invention, Figure 5 As shown, the connecting rod body 21 is an arc-shaped rod body, and one end of the connecting rod body 21 is connected to the crest 114 of the previous group of support rod components 10. A smooth transition is used at the connection between one end of the connecting rod body 21 and the previous group of crests 114 to reduce the stimulation of the peripheral arterial stent to the inner wall of the blood vessel. The other end of the connecting rod body 21 is connected to the trough 113 of the next group of support rod components 10. Similarly, a smooth transition is used at the connection between the other end of the connecting rod body 21 and the next group of troughs 113.

[0049] In one embodiment of the present invention, Figure 5As shown, the connecting rod body 21 extends along the tangent function curve, achieving a smooth transition between the connection between one end of the connecting rod body 21 and the previous group of wave crests 114, and the connection between the other end of the connecting rod body 21 and the next group of wave troughs 113. The design of the connecting rod body 21 as a tangent function curve is conducive to the bending and twisting of the bracket in the axial direction, and improves the flexibility. The width of the connecting rod body 21 can be equal to the width of the first support portion 111 and the width of the second support portion 112, or it can be smaller than the width of the first support portion 111 and the width of the second support portion 112. In this embodiment, the width of the connecting rod body 21 is 0.05-0.10mm.

[0050] In one embodiment of the present invention, Figure 6 As shown, the connecting rod bodies 21 of the same group of connecting rod components 20 are arranged at equal intervals, and five support rod units 11 are spaced between two adjacent connecting rod bodies 21. Of course, the distance between two adjacent connecting rod bodies 21 is not limited thereto, and four, six or more support rod units 11 are spaced between two adjacent connecting rod bodies 21. The connecting rod bodies 21 of two adjacent groups of connecting rod components 20 are staggered, and the adjacent connecting rod bodies 21 are symmetrical to each other, which can conform to the axial rotation of the stent in the counterclockwise or clockwise direction to improve the compliance performance of the peripheral artery stent.

[0051] In one embodiment of the present invention, Figure 6 As shown, the wave crests 114 of one group of support rod components 10 in two adjacent groups of support rod components 10 are arranged alternately with the wave troughs 113 of the other group of support rod components 10. Specifically, the wave troughs 113 of the upper group of support rod components 10 are arranged to the left relative to the wave crests 114 of the lower group of support rod components 10, and such an arrangement can increase the length of the connecting rod body 21, increase the contact surface between the peripheral artery stent and the inner wall of the blood vessel, further reduce the unit stress borne by the blood vessel wall, and prevent the hyperplasia of the intimal membrane of the blood vessel.

[0052] like Figure 6 As shown, in the upper frame, the first end of the second support portion 112 of the upper group is connected to the second end of the second support portion 112 of the lower group through the connecting rod body 21. In the lower frame, the first end of the first support portion 111 of the upper group is connected to the second end of the first support portion 111 of the lower group through the connecting rod body 21.

[0053] In one embodiment of the present invention, Figure 4 yes Figure 2 The local enlarged structural diagram at B is as follows: Figure 4As shown, at least one crest 114 of the support rod component 10 at the distal end and at least one trough 113 of the support rod component 10 at the proximal end are respectively provided with a developing ring 13, and the developing ring 13 is provided with a developing point 14, and the material of the developing point 14 is a combination of one or more of tantalum, gold, and platinum. A circular hole is provided at the center of the developing ring 13, and the developing point 14 is provided in the circular hole of the developing ring 13. The apertures of the developing rings 13 at both ends of the peripheral artery stent can be the same or different. Here, the inner diameter of the circular hole is recorded as φ1, and the outer diameter of the developing ring is recorded as φ2. In this embodiment, the value range of φ1 is 0.3-0.6mm, and the value range of φ2 is 0.9-1.4mm.

[0054] In a specific embodiment of the present invention, the five wave crests 114 of the support rod component 10 at the distal end are provided with developing rings 13, and the five developing rings 13 at the distal end are arranged at equal intervals along the circumference of the peripheral artery stent; of course, the number of developing rings 13 at the distal end is not limited thereto, and three, four, six or more can also be provided. The five wave troughs 113 of the support rod component 10 at the proximal end are respectively provided with developing rings 13, and the five developing rings 13 at the proximal end are arranged at equal intervals along the circumference of the peripheral artery stent; of course, the number of developing rings 13 at the proximal end is not limited thereto, and three, four, six or more can also be provided.

[0055] In a preferred embodiment of the present invention, the surface of the peripheral artery stent is coated with an anticoagulant coating. By coating the surface of the peripheral artery stent with the anticoagulant coating, the peripheral artery stent can be prevented from contacting with blood and forming a thrombus on the surface of the peripheral artery stent.

[0056] Furthermore, the anticoagulant coating is a combination of one or more of a heparin coating, a phosphorylcholine coating, a polypeptide coating, and a nano coating.

[0057] Figure 7 The schematic diagram of the use principle of the peripheral artery stent provided by the embodiment of the present invention is illustrated as follows: Figure 7 As shown, the principle of use of peripheral artery stents:

[0058] When in use, the peripheral artery stent is delivered to the location of the diseased blood vessel 30. After the stent is completely released, the stent follows the blood vessel path and closely adheres to the blood vessel wall, supporting the diseased area. Since the support components and connecting rod components of the stent extend along the tangent function curve and are staggered, the flexibility of the stent in the axial and radial directions is improved, so that the stent can bend, stretch, compress and deform accordingly according to the shape of the blood vessel path without causing damage to the blood vessel wall.

[0059] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A peripheral artery stent, characterized in that: include: A plurality of groups of support rod components, wherein the plurality of groups of support rod components are arranged in sequence from the proximal end to the distal end, the support rod components include a plurality of groups of support rod units connected in sequence along the circumferential direction, the number of support rod units in each group of the support rod components is equal, the support rod units include a first support portion and a second support portion that are symmetrically arranged, and the angle between the first support portion and the second support portion gradually increases from the proximal end to the distal end; in each group of support rod units, the first end of the first support portion is connected to the first end of the second support portion to form a trough; in two adjacent groups of support rod units, the second end of one group of the first support portions is connected to the second end of the other group of the second support portions to form a peak; A plurality of groups of connecting rod components, wherein the plurality of groups of connecting rod components are arranged one by one between two adjacent groups of supporting rod components; The peripheral artery stent is tapered, and the cross-sectional area of ​​the proximal end of the peripheral artery stent is larger than the cross-sectional area of ​​the distal end of the peripheral artery stent; The connecting rod component comprises: A plurality of connecting rod bodies, wherein the plurality of connecting rod bodies are evenly spaced along the circumferential direction, one end of the connecting rod body is connected to the crest of one group of the support rod parts in two adjacent groups of the support rod parts, and the other end of the connecting rod body is connected to the trough of the other group of the support rod parts; the connecting rod body extends along a tangent function curve so that the connection between one end of the connecting rod body and the crest of the previous group and the connection between the other end of the connecting rod body and the trough of the next group are smoothly transitioned; the first end of the second support portion of the previous group is connected to the second end of the second support portion of the adjacent next group through the connecting rod body, and the first end of the first support portion of the adjacent next group is connected to the second end of the first support portion of the next group through the connecting rod body; the first support portion and the second support portion both extend along the tangent function curve; The connecting rod bodies of the same group of connecting rod components are arranged at equal intervals, the connecting rod bodies of two adjacent groups of connecting rod components are arranged alternately, and the adjacent connecting rod bodies are symmetrical to each other to comply with the counterclockwise or clockwise axial rotation of the bracket.

2. The peripheral artery stent according to claim 1, characterized in that: The wave crests of one group of the support rod components in two adjacent groups of the support rod components are arranged alternately with the wave troughs of the other group of the support rod components.

3. The peripheral artery stent according to claim 1, characterized in that: The length of the peripheral artery stent is 20-200 mm, the taper of the peripheral artery stent is 0.02-0.05, and the diameter of the proximal end of the peripheral artery stent is 3-10 mm.

4. The peripheral artery stent according to any one of claims 1 to 3, characterized in that: At least one wave crest of the support rod component at the distal end and at least one wave trough of the support rod component at the proximal end are respectively provided with developing rings, and the developing rings are provided with developing points.

5. The peripheral artery stent according to any one of claims 1 to 3, characterized in that: The surface of the peripheral artery stent is coated with an anticoagulant coating.

6. The peripheral artery stent according to claim 5, characterized in that: The anticoagulant coating is a combination of one or more of a heparin coating, a phosphorylcholine coating, a polypeptide coating, and a nano coating.

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