A myceliopthora thermophila rice fermentation extraction compound, and a preparation method and application thereof

By combining rice fermentation extract of *Cicadaemonorops spp.* with a polymer network of hyaluronic acid, the problems of poor healing effect and numerous side effects of wound healing materials have been solved, achieving the effects of wound repair and hair follicle regeneration. It is suitable for both wound healing materials and hair follicle growth materials.

CN118384240BActive Publication Date: 2026-05-26NANJING UNIV OF TRADITIONAL CHINESE MEDICINE +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NANJING UNIV OF TRADITIONAL CHINESE MEDICINE
Filing Date
2024-03-15
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

Existing wound healing materials suffer from poor healing effects and numerous side effects. In particular, they lack effective substances to promote the regeneration of skin appendages such as hair follicles, resulting in wound healing remaining at the repair stage rather than regeneration.

Method used

It uses a polymer network composed of rice fermentation extract of Cymbidium faberi and hyaluronic acid to synergistically reduce inflammation and promote wound healing, especially promoting the regeneration of normal skin appendages such as hair follicles.

Benefits of technology

It improves wound repair and healing, promotes hair follicle formation, has no side effects, is highly safe, and is suitable for industrial production.

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Abstract

The application discloses a kind of Ampelomyces quisqualis rice fermentation extraction compound and preparation method and application thereof, its preparation method is: preparation Ampelomyces quisqualis seed liquid;Preparation rice fermentation medium, Ampelomyces quisqualis seed liquid is used to ferment medium, under 22±2 ℃, natural fermentation 5~60 days, after drying, fermentation dry material is obtained for future use;After sieving, fermentation dry material is crushed and added with water, after heating reflux, centrifugation and filtration supernatant, Ampelomyces quisqualis rice fermentation extract is obtained;Hyaluronic acid or sodium hyaluronate is added to Ampelomyces quisqualis rice fermentation extract, and the compound is obtained after swelling and drying.The application is formed by Ampelomyces quisqualis rice fermentation extract and hyaluronic acid (sodium), and the polymer grid can be synergized and quickly anti-inflammatory and promote wound healing, especially promote the regeneration of normal skin appendages such as hair follicle to heal, effectively improve the repair and cure effect on various skin and mucosa damage, and has no negative effect.
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