A mild cleansing milk for repairing skin barrier and preparation method thereof

Abstract

The present invention relates to a mild cleanser for repairing skin barrier and a preparation method thereof, wherein the mild cleanser for repairing skin barrier includes the following components by mass: 10-20 parts of N-acyl sodium glutamate, 5-10 parts of propylene glycol, 5-10 parts of glycerol, 5-10 parts of modified diatomaceous earth, 1-5 parts of cellulose, 1-5 parts of amino acids, 0.5-5 parts of active ingredients, 1-10 parts of auxiliary agents, and water; wherein the modified diatomaceous earth is hyaluronic acid modified diatomaceous earth. The present invention effectively improves the compatibility between components, improves the stability of the cleanser, improves the effect of the product, can meet the performance requirements of gentleness and repairing skin barrier, and has good application prospects.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to a mild cleansing milk for repairing skin barrier and a preparation method thereof. Background Art

[0002] Due to aging, changes in lifestyle and other reasons, people find that their skin has been damaged to varying degrees, and they are paying more and more attention to skin care. Cleansing the skin is the first step in skin care.

[0003] Surfactants are usually added to current skin cleansing products to remove oil and clean pores, but too much surfactant will cause excessive dryness of the skin, making it difficult to achieve a balance of water and oil, and ultimately irritating and damaging the skin. Amino acids, animal and plant extracts and other ingredients are usually used as raw materials in existing products to maintain and repair the skin, but the active ingredients are difficult to absorb efficiently and cannot be preserved for a long time.

[0004] At the same time, ingredients such as diatomaceous earth in facial cleansers contain a large amount of highly polar silanol groups and have low compatibility with organic components. Therefore, after mixing multiple ingredients, they are prone to uneven dispersion, agglomeration, and precipitation. After long-term storage, they may also clump and stratify, which not only affects the appearance of the product, but also reduces the effectiveness of the cleanser.

[0005] In summary, it is necessary to develop a new technical solution to solve the deficiencies in the prior art. Summary of the invention

[0006] Based on this, the present invention provides a mild cleansing milk for repairing skin barrier and a preparation method thereof. The present invention adopts sodium N-acyl glutamate, propylene glycol, glycerin, modified diatomaceous earth, amino acids and other ingredients to effectively improve the compatibility between components, enhance the stability of the cleansing milk, improve the effect of the product, and can meet the performance requirements of mildness and repairing skin barrier.

[0007] One object of the present invention is to provide a mild cleansing milk for repairing skin barrier, wherein the mild cleansing milk for repairing skin barrier comprises the following components in parts by weight:

[0008]

[0009]

[0010] in,

[0011] The modified diatomaceous earth is hyaluronic acid modified diatomaceous earth.

[0012] Furthermore, the cellulose is selected from one or more of hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose and carboxymethyl cellulose.

[0013] Furthermore, the amino acid is selected from one or more of threonine, alanine, aspartic acid, leucine, methionine, glutamic acid, glycine and histidine.

[0014] Furthermore, the active ingredient is selected from one or more of plant extracts, animal extracts, proteases, polypeptides, and vitamins.

[0015] Furthermore, the auxiliary agent is selected from one or more of a moisturizer, a thickener, a surfactant, a preservative, an antioxidant, an emulsifier, a stabilizer, a flavor, and a pigment.

[0016] Another object of the present invention is to provide a method for preparing the mild cleansing milk for repairing the skin barrier, the method for preparing the mild cleansing milk for repairing the skin barrier comprising the following steps:

[0017] S1, adding diatomaceous earth to an alkaline solution, ultrasonically treating, purifying, mixing with glucose, ball milling, and purifying to obtain hydroxylated diatomaceous earth;

[0018] S2, blending the hydroxylated diatomaceous earth and hyaluronic acid, heating and stirring to react, and then grinding to obtain modified diatomaceous earth;

[0019] S3, blending the modified diatomaceous earth with other ingredients, stirring and dispersing them evenly to obtain a product.

[0020] Furthermore, in step S1, the ultrasonic treatment time is 1-3 hours.

[0021] Furthermore, in step S1, the mass ratio of diatomaceous earth to glucose is 1:(1-5).

[0022] Furthermore, in step S2, the temperature of the heating and stirring reaction is 50-70°C and the time is 3-6h.

[0023] Furthermore, in step S2, the mass ratio of the hydroxylated diatomaceous earth to hyaluronic acid is (10-20):1.

[0024] The present invention has the following beneficial effects:

[0025] In the gentle cleanser for repairing skin barrier provided by the present invention, N-acyl sodium glutamate, propylene glycol, and glycerol with good biological affinity and low irritation are used as main components, and modified diatomaceous earth and amino acids and active ingredients with nourishing and repairing skin effects are compounded. In modified diatomaceous earth, diatomaceous earth is first hydroxylated to increase the content of surface active silanols, and then hydroxylated diatomaceous earth and hyaluronic acid are mixed and reacted, thereby introducing the organic polysaccharide structure of hyaluronic acid into diatomaceous earth, effectively improving the compatibility of modified diatomaceous earth with other organic components and active ingredients, avoiding the reunion of components, and forming a more stable and uniform system. On the other hand, the modified diatomaceous earth surface has a large number of hydroxyl and carboxyl active groups, and more active sites are introduced, so that it can be adsorbed and combined with active ingredients such as amino acids, and the stability of active ingredients is enhanced when stored; the modified diatomaceous earth also has better skin affinity, and can promote the absorption of active ingredients when used, realizing the synergistic effect between multiple components, and achieving the effect of gentle cleaning and efficient skin repair. DETAILED DESCRIPTION

[0026] In order to more clearly illustrate the technical solution of the present invention, the following examples are listed. Unless otherwise stated, the raw materials, reactions and post-treatment methods shown in the examples are common raw materials on the market and technical methods well known to those skilled in the art.

[0027] The words "preferred", "preferably", "more preferably", etc. in the present invention refer to embodiments of the present invention that can provide certain beneficial effects in certain circumstances. However, other embodiments may also be preferred under the same circumstances or other circumstances. In addition, the description of one or more preferred embodiments does not imply that other embodiments are not applicable, nor is it intended to exclude other embodiments from the scope of the present invention.

[0028] It should be understood that, except in any operating examples, or where otherwise indicated, all numbers indicating, for example, the amounts of ingredients used in the specification and claims should be understood to be modified in all cases by the term "about". Therefore, unless indicated to the contrary, the numerical parameters set forth in the following specification and the appended claims are approximate values ​​that vary depending on the desired properties to be obtained by the present invention.

[0029] The "parts" in the embodiments of the present invention refer to parts by mass.

[0030] Example 1

[0031] A mild cleansing milk for repairing skin barrier, comprising the following ingredients in parts by weight:

[0032]

[0033] The method for preparing the mild cleanser for repairing the skin barrier comprises the following steps:

[0034] S1, soaking diatomaceous earth in 5 mol / L sodium hydroxide solution, ultrasonically treating for 3 h, then washing to neutrality, drying and mixing with glucose (diatomaceous earth: glucose = 1:5, m / m) for ball milling (ball to material ratio 5:1), washing, centrifuging and drying to obtain hydroxylated diatomaceous earth;

[0035] S2, using ethanol as solvent, adding the hydroxylated diatomaceous earth and hyaluronic acid in a mass ratio of 15:1, and then adding 1wt% concentrated sulfuric acid to the system, heating and stirring at 60°C for 4h, centrifuging, washing, drying, and grinding through a 200-mesh sieve to obtain modified diatomaceous earth;

[0036] S3. Blending the modified diatomaceous earth with other ingredients according to the above mass fractions, stirring and dispersing them uniformly to obtain a product.

[0037] Example 2

[0038] A mild cleansing milk for repairing skin barrier, comprising the following ingredients in parts by weight:

[0039]

[0040] The method for preparing the mild cleanser for repairing the skin barrier comprises the following steps:

[0041] S1, soaking diatomaceous earth in 5 mol / L sodium hydroxide solution, ultrasonically treating for 3 h, then washing to neutrality, drying and mixing with glucose (diatomaceous earth: glucose = 1:5, m / m) for ball milling (ball to material ratio 5:1), washing, centrifuging and drying to obtain hydroxylated diatomaceous earth;

[0042] S2, using ethanol as solvent, adding the hydroxylated diatomaceous earth and hyaluronic acid in a mass ratio of 15:1, and then adding 1wt% concentrated sulfuric acid to the system, heating and stirring at 60°C for 4h, centrifuging, washing, drying, and grinding through a 200-mesh sieve to obtain modified diatomaceous earth;

[0043] S3. Blending the modified diatomaceous earth with other ingredients according to the above mass fractions, stirring and dispersing them uniformly to obtain a product.

[0044] Example 3

[0045] A mild cleansing milk for repairing skin barrier, comprising the following ingredients in parts by weight:

[0046]

[0047] The method for preparing the mild cleanser for repairing the skin barrier comprises the following steps:

[0048] S1, soaking diatomaceous earth in 5 mol / L sodium hydroxide solution, ultrasonically treating for 3 h, then washing to neutrality, drying and mixing with glucose (diatomaceous earth: glucose = 1:5, m / m) for ball milling (ball to material ratio 5:1), washing, centrifuging and drying to obtain hydroxylated diatomaceous earth;

[0049] S2, using ethanol as solvent, adding the hydroxylated diatomaceous earth and hyaluronic acid in a mass ratio of 15:1, and then adding 1wt% concentrated sulfuric acid to the system, heating and stirring at 60°C for 4h, centrifuging, washing, drying, and grinding through a 200-mesh sieve to obtain modified diatomaceous earth;

[0050] S3. Blending the modified diatomaceous earth with other ingredients according to the above mass fractions, stirring and dispersing them uniformly to obtain a product.

[0051] Comparative Example

[0052] A mild cleanser for repairing skin barrier. The difference between this comparative example and Example 1 is that the mass of modified diatomaceous earth is replaced by a mixture of unmodified diatomaceous earth and hyaluronic acid in a mass ratio of 15:1, and the other ingredients and preparation method are the same as those in Example 1.

[0053] Test Case

[0054] The performance of the mild cleansing milks for repairing the skin barrier prepared in Examples 1-3 and Comparative Examples was tested.

[0055] The test method is as follows:

[0056] Stability test: Seal the sample and place it at a constant temperature of 5°C for 60 days, then check the appearance changes. If there is obvious stratification, agglomeration, or hardening, it will be judged as unqualified.

[0057] Cleansing, mildness and moisturizing performance test: 40 volunteers were divided into 4 groups, each with 10 people. Each group tried the facial cleansing milk products prepared in Examples 1-3 and the comparative example respectively. Each person applied 10g of the sample evenly on the face. After 2 minutes, rinsed it with clean water. Each volunteer was asked to score the cleaning effect, mildness and moisturizing effect of the sample (1-10 points, the highest being 10 points), and the average value of each group was calculated.

[0058] The test results are shown in Table 1.

[0059] Table 1 Performance test results

[0060] project Example 1 Example 2 Example 3 Comparative Example 1 stability qualified qualified qualified Failure Cleaning performance 9.2 9.4 9.1 8.9 Mildness 9.5 9.4 9.6 9.3 Moisturizing properties 8.2 7.9 8.0 7.3

[0061] According to Table 1, it can be seen that the mild cleansing milk for repairing the skin barrier prepared in Examples 1-3 of the present invention has excellent stability, good cleaning performance and moisturizing performance, and good mildness; the comparative example replaces the modified diatomaceous earth with a physical mixture of diatomaceous earth and hyaluronic acid, resulting in a decrease in the dispersibility and compatibility of the components, a significant decrease in product stability, and a decrease in the synergistic effect between the components, and the washing and care function is also weakened compared with the embodiment. In summary, the mild cleansing milk for repairing the skin barrier of the present invention has good application prospects.

[0062] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be considered exemplary and non-restrictive in all respects, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention.

[0063] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A mild cleanser for repairing skin barrier, characterized in that: The mild cleanser for repairing the skin barrier is composed of the following components in parts by mass: 10-20 parts of sodium N-acyl glutamate Propylene glycol 5-10 parts 5-10 parts glycerin Modified diatomaceous earth 5-10 parts 1-5 parts of cellulose Amino Acids 1-5 parts Active ingredient 0.5-5 parts 1-10 parts of additives water; in, The modified diatomaceous earth is hyaluronic acid modified diatomaceous earth; The method for preparing the mild cleanser for repairing the skin barrier comprises the following steps: S1, adding diatomaceous earth to an alkaline solution, ultrasonically treating, purifying, mixing with glucose, ball milling, and purifying to obtain hydroxylated diatomaceous earth; S2, using ethanol as a solvent, blending the hydroxylated diatomaceous earth and hyaluronic acid, then adding 1 wt% of concentrated sulfuric acid to the system, heating and stirring to react, and then grinding to obtain modified diatomaceous earth; S3, blending the modified diatomaceous earth with other ingredients, stirring and dispersing them evenly to obtain a product; In step S1, the mass ratio of diatomaceous earth to glucose is 1:1-5; In step S2, the temperature of the heating and stirring reaction is 50-70°C and the time is 3-6 h; In step S2, the mass ratio of the hydroxylated diatomaceous earth to hyaluronic acid is 10-20:1; The propylene glycol is 1,3-propylene glycol; The cellulose is selected from one or more of hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose and carboxymethyl cellulose; The amino acid is selected from one or more of threonine, alanine, aspartic acid, leucine, methionine, glutamic acid, glycine, and histidine; The active ingredients are tea polyphenols, seaweed polysaccharides and tremella polysaccharides.

2. The mild cleanser for repairing skin barrier according to claim 1, characterized in that: The auxiliary agent is selected from one or more of moisturizers, thickeners, preservatives, antioxidants, emulsifiers, flavors, and pigments.

3. The mild cleanser for repairing skin barrier according to claim 1, characterized in that: In step S1, the ultrasonic treatment time is 1-3 h.

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