Blood analyzer and blood analysis method

Abstract

The application discloses a blood analyzer and a blood analysis method. A control module of the blood analyzer acquires optical configuration parameters of an optical detection module based on a first detection result of a first detection module, so that the optical configuration parameters of the optical detection module correspond to the blood cell size of a sample to be detected. The blood analyzer of the embodiment can detect blood cells of various sizes and shapes, improve the accuracy of the blood analyzer, and improve the reliability of the blood analyzer.

Description

Technical Field

[0001] This application relates to the field of blood analysis technology, and in particular to a blood analyzer and a blood analysis method. Background Technology

[0002] A blood analyzer is an instrument used to detect parameters such as the number, volume, and proportion of blood cells (red blood cells, white blood cells, platelets, reticulocytes, etc.) in the blood. With technological advancements and scientific development, the functions of blood analyzers are constantly expanding, their performance is continuously improving, and their level of automation is also constantly increasing.

[0003] In analyzing reticulocytes, existing analyzers typically use fluorescent staining and laser measurement techniques. However, fluorescent dyes are expensive, making the cost of using this technique for reticulocyte measurement extremely high. Therefore, some manufacturers use chemical staining and laser scattering techniques for reticulocyte measurement. However, because the colorimetric intensity of chemical dyes is lower than that of fluorescent dyes, the accuracy of the measurement results is low, which reduces the reliability of the blood analyzer. Summary of the Invention

[0004] To address the aforementioned technical problems, this application provides a blood analyzer and a blood analysis method.

[0005] To address the aforementioned problems, this application provides a first technical solution: a blood analyzer comprising a first detection module, a control module, and an optical detection module; the first detection module is used to perform a first detection on a sample to be tested to obtain a first detection result of the sample; the control module is used to obtain optical configuration parameters corresponding to the first detection result and configure the optical detection module according to the optical configuration parameters; the optical detection module is used to perform a second detection on the sample to be tested based on the configured optical configuration parameters and obtain a second detection result of the sample; the control module is further used to obtain an analysis result of the sample to be tested based on the first detection result and the second detection result.

[0006] Wherein, the first detection module includes an impedance detection module and / or the optical detection module; the control module is used to control the impedance detection module to detect the sample under test in order to obtain the impedance detection result of the sample under test; and / or, the control module controls the optical detection module to detect the sample under test in order to obtain the optical detection result of the sample under test.

[0007] The control module is further configured to acquire the animal type of the sample to be tested, the animal type including a first animal type and a second animal type, wherein the red blood cell size of the sample to be tested of the first animal type is larger than the red blood cell size of the sample to be tested of the second animal type; the control module is further configured to control the impedance detection module to perform a first detection on the sample to be tested in response to the sample to be tested being of the first animal type, and the control module is further configured to control the optical detection module to perform a first detection on the sample to be tested in response to the sample to be tested being of the second animal type.

[0008] The optical configuration parameters include at least one of the following: laser power parameters of the optical detection module, receiver gain parameters, sample flow parameters, and spot size parameters.

[0009] The control module is further configured to: when it is determined that the first detection result is not within a preset range, obtain the optical configuration parameters corresponding to the first detection result; or, when it is determined that the first detection result is not within the preset range, generate a warning message and send the warning message to the visualization interface. The control module is further configured to receive confirmation information returned by the visualization interface, so as to obtain the optical configuration parameters based on the first detection result when the confirmation message includes a test instruction.

[0010] The preset range includes a preset threshold set based on the volume deviation of red blood cells and platelets. The control module is also used to obtain the volume deviation data of red blood cells and platelets of the sample to be tested based on the first detection result; and to determine that the first detection result is not in the preset range when the volume deviation data is less than the preset threshold.

[0011] The blood analyzer further includes a sample preparation module and a sampling module. The sampling module is used to sample a sample tube to obtain a blood sample. The sample preparation module is used to prepare the blood sample to obtain the first test sample. The first detection module is used to perform a first detection on a portion of the first test sample. The optical detection module performs a second detection on the remaining first test sample based on the optical configuration parameters. Alternatively, the sample preparation module is also used to re-prepare the blood sample to obtain the second test sample. The first detection module performs a first detection on the first test sample, and the optical detection module performs a second detection on the second test sample based on the optical configuration parameters.

[0012] The optical detection module includes a light emitting unit for emitting laser light, and the optical configuration parameters include the laser power parameters of the light emitting unit. The control module includes: a controller for acquiring control parameters and generating control signals based on the control parameters, wherein the control parameters correspond to the laser power parameters; a voltage conversion unit connected to the controller for receiving the control signals and converting the control signals into a driving voltage; and a driving circuit unit connected to the voltage conversion unit for receiving the driving voltage and converting the driving voltage into a driving current. The driving circuit unit is connected to the light emitting unit, and the driving circuit unit drives the light emitting unit to output laser light through the driving current to configure the laser power parameters of the optical detection module.

[0013] To address the aforementioned problems, this application provides a second technical solution: an animal blood analyzer, comprising a first detection module for detecting animal blood samples to obtain a first detection result; a control module for acquiring optical configuration parameters corresponding to the first detection result and configuring the optical detection module according to the optical configuration parameters; the optical detection module for detecting the animal blood sample based on the configured optical configuration parameters and obtaining a second detection result; and the control module for obtaining an analysis result of the animal blood sample based on the first and second detection results; wherein the first detection module is used to perform impedance detection or optical detection on the animal blood sample according to the animal type of the animal blood sample, or the control module is used to acquire the optical configuration parameters according to the animal type of the animal blood sample and the first detection result.

[0014] To address the aforementioned issues, this application provides a third technical solution: a blood analysis method comprising: testing a sample to be tested to obtain a first test result of the sample; obtaining optical configuration parameters corresponding to the first test result; performing a second test on the sample to be tested based on the optical configuration parameters to obtain a second test result of the sample; and obtaining an analysis result of the sample to be tested based on the first test result and the second test result.

[0015] This application provides a blood analyzer and a blood analysis method. The control module of the blood analyzer obtains the optical configuration parameters of the optical detection module based on the first detection result of the first detection module, so that the optical configuration parameters of the optical detection module correspond to the blood cell size of the sample to be tested. This enables the blood analyzer of this embodiment to detect blood cells of various shapes and sizes, thereby improving the accuracy and reliability of the blood analyzer. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein:

[0017] Figure 1 This is a schematic diagram of the structure of an embodiment of the blood analyzer provided in this application;

[0018] Figure 2 This is a schematic diagram of another embodiment of the blood analyzer provided in this application;

[0019] Figure 3 This is a schematic flowchart of an embodiment of the blood analysis method provided in this application;

[0020] Figure 4 This is a schematic diagram of another embodiment of the blood analyzer provided in this application. Detailed Implementation

[0021] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0022] It should be noted that if the embodiments of this application involve directional indicators (such as up, down, left, right, front, back, etc.), the directional indicators are only used to explain the relative positional relationship and movement of the components in a certain specific posture (as shown in the figure). If the specific posture changes, the directional indicators will also change accordingly.

[0023] Furthermore, if the embodiments of this application involve descriptions such as "first" or "second," these descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, features defined with "first" or "second" may explicitly or implicitly include at least one of those features. Additionally, the technical solutions of various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. If the combination of technical solutions is contradictory or impossible to implement, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection claimed in this application.

[0024] Blood analyzers are used to test blood samples, which typically include reticulocyte detection. Existing methods for analyzing reticulocytes generally include fluorescent nucleic acid staining and chemical staining with laser scattering.

[0025] In measuring reticulocytes using fluorescent nucleic acid staining, the high cost of fluorescent dyes and the high hardware cost of the fluorescence detection module hinder its further application. To address this, existing technologies employ chemical staining and laser scattering to detect reticulocytes and reduce costs. However, this method involves manually staining the sample before sending it to a blood analyzer, which has low automation, hindering analytical efficiency. Furthermore, this method is problematic when dealing with blood cell samples from different species or with different morphologies. For example, in animal samples, the smaller size of red blood cells and the similar size of platelets make it easy for the blood analyzer to confuse them, affecting the accuracy of red blood cell and platelet detection, and consequently, the accuracy of reticulocyte measurement.

[0026] In view of this, this application proposes a blood analyzer for performing routine blood tests on blood cell samples to obtain blood cell parameters such as red blood cells, platelets, white blood cells, and reticulocytes. Specifically, the blood analyzer of this application can perform blood analysis according to the size of blood cell samples of different species or different morphologies, thereby improving the accuracy of blood cell parameters.

[0027] Please see Figure 1 , Figure 1 This is a schematic diagram of an embodiment of the blood analyzer provided in this application. Figure 1 As shown, the blood analyzer in this embodiment includes a control module 10, a first detection module 20, and an optical detection module 30. The control module 10 is connected to the first detection module 20 and the optical detection module 30 respectively to control the first detection module 20 and the optical detection module 30 to detect the sample to be tested.

[0028] The first detection module 20 is used to perform a first detection on the sample to be tested to obtain a first detection result of the sample to be tested; the control module 10 is used to obtain the optical configuration parameters corresponding to the first detection result and configure the optical detection module 30 according to the optical configuration parameters; the optical detection module 30 is used to perform a second detection on the sample to be tested based on the configured optical configuration parameters and obtain a second detection result of the sample to be tested; the control module 10 is also used to obtain the analysis result of the sample to be tested based on the first detection result and the second detection result.

[0029] Specifically, the first detection module 20 of the blood analyzer can be used for impedance detection of the sample to be tested, or it can be used for optical detection of the sample to be tested. In one embodiment, the first detection module 20 and the optical detection module 30 can be detection modules using the same detection methodology, that is, both the first detection module 20 and the optical detection module 30 are optical detection modules 30; in another embodiment, the first detection module 20 and the optical detection module 30 can be detection modules using different detection methodologies, that is, the blood analyzer is equipped with both an impedance detection module and an optical detection module 30. The detection methodology used by the first detection module 20 is related to factors such as the detection item, the species type of the sample to be tested, the morphology of blood cells, or the cell size; the control module 10 can be a programmable controller, such as a PLC controller, a microcontroller controller, a computer host CPU controller, etc., and is not specifically limited here.

[0030] The control module 10 acquires the first detection result from the first detection module 20. In one embodiment, the first detection result may be the blood cell count result, such as red blood cells, platelets, and white blood cells. For example, the first detection result includes the mean corpuscular volume (MCV), mean platelet volume (MPV), and red blood cell distribution coefficient (RDW). In other embodiments, the first detection result may also be a statistical histogram or scatter plot of blood cells. No specific limitation is made on the first detection result here.

[0031] The control module 10 pre-stores a first correspondence between the first detection result and the optical configuration parameters. After acquiring the first detection result, the control module 10 can acquire the optical configuration parameters of the optical detection module 30 corresponding to the first detection result. In an optional embodiment, the blood cell count result can be set with multiple counting intervals, each with corresponding optical configuration parameters. This allows the control module 10 to select the optical configuration parameters corresponding to the first detection result and configure the optical detection module 30 accordingly. This enables the optical detection module 30 to perform a second detection on the sample based on the configured optical configuration parameters to obtain a second detection result.

[0032] The control module 10 acquires the analysis results of the sample to be tested based on the first detection result and the second detection result. The analysis results of the sample to be tested can be optical configuration parameters obtained by adjusting the first detection result based on the second detection result, or the second detection result can be used as the analysis result of the sample to be tested. The analysis results can be adjusted according to user needs, and no specific limitation is made to the analysis results here. In an optional embodiment, the analysis results may include at least one of the following: reticulocyte count results, red blood cell count results, and platelet count results. Since the analysis results are acquired based on the first and second detection results, the blood analyzer in this embodiment can accurately correspond to the size of red blood cells, and the accuracy of the reticulocyte count results is higher.

[0033] In this embodiment, the control module 10 obtains the optical configuration parameters of the optical detection module 30 based on the first detection result of the first detection module 20, so that the optical configuration parameters of the optical detection module 30 correspond to the blood cell size of the sample to be tested, enabling the blood analyzer of this embodiment to detect blood cells of various shapes and sizes, thereby improving the accuracy of the blood analyzer; thus, the cell analyzer is adapted to chemical dye detection and can reduce costs while ensuring the reliability of the detection results.

[0034] Optionally, the first detection module 20 includes an impedance detection module and / or an optical detection module 30. The control module 10 is used to control the impedance detection module to detect the sample under test in order to obtain the impedance detection result of the sample under test. And / or, the control module 10 can also be used to control the optical detection module 30 to detect the sample under test in order to obtain the optical detection result of the sample under test.

[0035] Specifically, in one embodiment, the blood analyzer is equipped with an optical detection module 30, which performs a first detection on the sample to obtain a first detection result. After the control module 10 obtains the optical configuration parameters corresponding to the first detection result, the optical detection module 30 performs a second detection on the sample based on the configured optical configuration parameters to obtain a second detection result. In another embodiment, the blood analyzer is equipped with an optical detection module 30 and an impedance detection module. The impedance detection module performs a first detection on the sample to obtain a first detection result. After the control module 10 obtains the optical configuration parameters corresponding to the first detection result, the optical detection module 30 performs a second detection on the sample based on the configured optical configuration parameters to obtain a second detection result. In yet another embodiment, the blood analyzer is equipped with an optical detection module 30 and an impedance detection module. The impedance detection module performs a first detection on the sample to obtain an impedance detection result, the optical detection module 30 performs a second detection on the sample to obtain an optical detection result, the control module 10 obtains the impedance detection result and the optical configuration parameters corresponding to the optical detection result, and the optical detection module 30 performs a third detection on the sample based on the configured optical configuration parameters to obtain a second detection result.

[0036] That is, the first detection result may include the impedance detection result and / or optical detection result of the sample to be tested. The impedance detection module and the optical detection module 30 are detection devices with different detection methodologies. The impedance detection module performs impedance detection on the sample to be tested using the Coulter principle to obtain blood cell parameters such as red blood cells, white blood cells, platelets, and reticulocytes. The optical detection module 30 obtains the scattered light from red blood cells, white blood cells, platelets, and reticulocytes at various angles using laser scattering method, so as to obtain the blood cell parameter results of the sample to be tested based on the scattered light signals at different angles. Since the optical detection module 30 and the impedance detection module use different detection methodologies, there will be a certain deviation between the impedance detection result and the optical detection result. The control module 10 obtains the first detection result based on the impedance detection result, the optical detection result, and the preset deviation correction parameters, and obtains the optical configuration parameters corresponding to the first detection result to improve the accuracy of blood analysis.

[0037] Optionally, the control module 10 is further configured to acquire the animal type of the sample to be tested, including a first animal type and a second animal type, wherein the red blood cell size of the sample to be tested of the first animal type is larger than the red blood cell size of the sample to be tested of the second animal type; the control module 10 is further configured to control the impedance detection module to perform a first detection on the sample to be tested in response to the sample to be tested being of the first animal type, and the control module 10 is further configured to control the optical detection module 30 to perform a first detection on the sample to be tested in response to the sample to be tested being of the second animal type.

[0038] Specifically, when a blood analyzer is used to analyze blood samples from various animal types, the red blood cells in animal blood samples are generally small, making it easy for the blood analyzer to confuse red blood cells and platelets when counting them, leading to a decrease in the accuracy of the counting results. Since the impedance detection module has higher analytical accuracy but higher cost, while the optical detection module 30 has lower detection cost, before using the blood analyzer to analyze the sample, the blood analyzer can identify the animal type of the sample by scanning the identification code of the sample using a barcode scanner, or the blood analyzer can obtain the animal type of the sample input by the user through a visual interface. This allows the control module 10 to select whether to perform impedance detection or optical detection on the sample based on the red blood cell size of the animal type.

[0039] Understandably, the first and second animal types mentioned above are used to distinguish between impedance detection and optical detection during the first test. The first animal type refers to animals with larger red blood cell sizes, and the second animal type refers to animals with smaller red blood cell sizes. In this embodiment, the blood analyzer performs impedance detection on the sample from the first animal type, effectively sharing the red blood cell detection results. Only a single, low-cost red blood cell washing reagent is needed to obtain the total red blood cell count. A second detection is then performed using the configured optical detection module to comprehensively obtain the reticulocyte count in the sample. This approach reduces costs while ensuring the accuracy of reticulocyte detection. For the sample from the second animal type with smaller red blood cell sizes, optical detection is directly used for the first test, improving the accuracy of small cell detection.

[0040] Optionally, the optical configuration parameters include at least one of the following: laser power parameters of the optical detection module 30, receiver gain parameters, sample flow parameters, and spot size parameters.

[0041] Specifically, the optical configuration parameters are the relevant parameters of the optical devices of the optical detection module 30. For example, the first optical detection module 30 may include a light emitting unit, a light receiver, and an optical flow chamber. The optical configuration parameters include, but are not limited to, the laser power parameters of the light emitting unit, the receiving end gain parameters of the light receiving component, the sample flow velocity and sample flow width of the optical flow chamber, and the size of the formed light spot.

[0042] In this embodiment, the control module 10 can obtain corresponding optical configuration parameters based on the first detection result. The optical configuration parameters may include at least one of the laser power parameters, receiver gain parameters, sample flow parameters, and spot size parameters of the optical detection module 30, so that the configuration of the optical devices of the optical detection module 30 can basically correspond to the blood cell size of the sample to be tested, thereby improving the accuracy of the blood analyzer in detecting blood cells of various shapes and sizes.

[0043] Optionally, the control module 10 is further configured to: obtain the optical configuration parameters corresponding to the first detection result when it is determined that the first detection result is not within the preset range; or, generate a warning message when it is determined that the first detection result is not within the preset range and send the warning message to the visualization interface. The control module 10 is further configured to receive the confirmation message returned by the visualization interface, so as to obtain the optical configuration parameters based on the first detection result when the confirmation message includes a test instruction.

[0044] Specifically, after acquiring the first detection result, the control module 10 determines whether the first detection result is within a preset range. For example, when the first detection result includes the mean corpuscular volume (MCV) and the mean platelet volume (MPV), the control module 10 determines whether the relative deviation between the MCV and MPV is greater than a preset threshold to determine whether the first detection result is within the preset range. When the first detection result is within the preset range, it indicates that the volume deviation between red blood cells and platelets is large, and there will be no detection error caused by confusion between red blood cells and platelets in the first detection result. The detection accuracy of the first detection result is high, and the control module 10 can directly output the analysis result of the sample to be tested based on the first detection result. When the first detection result is not within the preset range, it indicates that the volume deviation between red blood cells and platelets is small. The first detection module 20 may confuse red blood cells and platelets when detecting the sample to be tested, thus causing inaccurate detection of red blood cell parameters. The control module 10 determines that the first detection result is not within the preset range.

[0045] In an optional implementation, the blood analyzer is used to test reticulocytes. Since the impedance detection module does not test reticulocytes when testing the sample, the first detection result must include at least the optical detection result before the control module 10 determines that the first detection result is not within the preset range and generates a warning message. For example, the first detection result is the optical detection result, or the first detection result includes the impedance detection result and the optical detection result.

[0046] When the control module 10 determines that the first detection result is not within the preset range, in one embodiment, the control module 10 can directly obtain the optical configuration parameters of the optical detection module 30 based on the first detection result. Specifically, the control module 10 pre-stores a first correspondence between the first detection result and the optical configuration parameters. For example, when the first detection result includes the mean corpuscular volume (MCV) and the optical correction parameter includes the laser power parameter, the mean corpuscular volume of the test sample has different ranges due to the different species types of the test sample. For example, when the mean corpuscular volume of the test sample is within a first preset range, the control module 10 determines that the test sample is a first type of sample, which is a human blood sample. The first preset range can be [80, 120], and the corresponding laser power parameter can be in the range of 3 to 5 mw, such as 3 mw, 3.5 mw, 4 mw, 5 mw, etc. When the mean corpuscular volume of the test sample is within a second preset range, the control module 10 determines that the test sample is a second type of sample, which is a dog blood sample. The second preset range can be [61.6, 73.5], and the corresponding laser power parameter can be in the range of 3.5 to 6 mw, such as 4 mw. 5mw, 5.5mw, 6mw, etc.; when the mean corpuscular volume of red blood cells in the sample to be tested is within the third preset range, the control module 10 determines that the sample to be tested is a third type of sample, which is sheep blood sample. The third preset range can be [14, 32.5], and the corresponding laser power parameters can be in the range of 10.0 to 15.0mw, for example, 10mw, 12mw, 13mw, 15mw, etc.; when the mean corpuscular volume of red blood cells in the sample to be tested is within the fourth preset range, the control module 10 determines that the sample to be tested is a third type of sample. For the fourth type of sample, the corresponding laser power parameters can be in the range of 6 to 9 mw, such as 6 mw, 7 mw, 8 mw, etc. When the mean corpuscular volume of red blood cells in the sample to be tested is within the fifth preset range, the control module 10 determines that the sample to be tested is the fifth type of sample, which is a cat blood sample. The fifth preset range can be [35.9, 53.1], and the corresponding laser power parameters can be in the range of 7.5 to 12 mw, such as 7.5 mw, 8 mw, 9 mw, 10 mw, 12 mw, etc.

[0047] For example, since the mean corpuscular volume of red blood cells of horses, cattle, rats, rabbits and pigs is relatively similar, when the mean corpuscular volume of red blood cells is within the fourth preset interval range, the fourth preset interval range can be [40, 70]. At this time, horse blood samples, cattle blood samples, rat blood samples, rabbit blood samples or pig blood samples are all identified as fourth type samples, so that when the control module 10 identifies the sample to be tested as a fourth type sample, the corresponding laser power parameters can be obtained in the range of 6 to 9 mw.

[0048] In another embodiment, when the control module 10 determines that the first detection result is not within the preset range, it generates a warning message and sends the warning message to the visualization interface. The control module 10 is also used to receive the confirmation message returned by the visualization interface, so as to obtain the optical configuration parameters based on the first detection result when the confirmation message includes a test instruction.

[0049] Specifically, after acquiring the first detection result, the control module 10 determines that the first detection result is outside the preset range, generates a corresponding warning message, and sends the warning message to the visualization interface. Specifically, the warning message may include the first prediction result, the deviation data between the first prediction result and the preset threshold, and a prompt message generated based on the first prediction result. The control module 10 sends the warning message to the visualization interface so that the user can determine the detection status of the sample to be tested based on the warning message on the visualization interface. For example, the warning message can be used to determine whether the sample to be tested exhibits an abnormal result during detection by the first detection module 20.

[0050] After receiving the warning information through the visual interface, the user clicks or performs other operations on the interface to generate corresponding confirmation information. This confirmation information may include test instructions and output instructions. For example, the test instruction instructs the control module 10 to control the optical detection module 30 to detect the sample under test, and the output instruction instructs the control module 10 to output a first detection result. When the confirmation information includes an output instruction, the control module 10 obtains the corresponding optical configuration parameters based on the first detection result.

[0051] In this embodiment, the control module 10 determines that the first detection result is not within a preset range, and selects the sample to be tested for a second detection. Since the optical detection module 30 performs a second detection on the sample to be tested according to the optical configuration parameters, the analysis result of the sample to be tested corresponds to the cell size of the sample to be tested, thereby improving the accuracy of the blood analyzer. When the control module 10 responds to the confirmation information including the test command, it controls the optical detection module 30 to perform a second detection. Since a manual confirmation step is set, the abnormal judgment of the first detection result is more accurate, thereby improving the user experience.

[0052] Optionally, the control module 10 is used to adjust the optical detection module 30 according to the optical configuration parameters so that the detection conditions of the optical detection module 30 correspond to the cell size of the sample to be tested. Here, cell size can be understood as the size of the red blood cells in the sample to be tested, reducing the possibility of the blood analyzer confusing red blood cells and platelets, and improving the accuracy of the blood analyzer.

[0053] Optionally, the preset range includes a preset threshold set based on the volume deviation of red blood cells and platelets. The control module 10 is also used to obtain the volume deviation data of red blood cells and platelets of the sample to be tested based on the first detection result; and when the volume deviation data is less than the preset threshold, it is determined that the first detection result is not within the preset range.

[0054] Specifically, the control module 10 acquires volume deviation data based on the first detection result. This volume deviation data indicates the range of volume differences between red blood cells and platelets. When the volume deviation data between red blood cells and platelets is less than a preset threshold, meaning the volumes of red blood cells and platelets in the sample are close, the control module 10 determines that the first detection result is not within the preset range. The first detection module 20 may confuse the counting of red blood cells and platelets, resulting in a decrease in the accuracy of the first detection result. When the volume deviation data between red blood cells and platelets is greater than or equal to the preset threshold, meaning the volume deviation between red blood cells and platelets in the sample is large, the control module 10 determines that the accuracy of the first detection result is within the preset range. In this case, the control module 10 may not control the optical detection module 30 to perform a second detection.

[0055] Since the blood analyzer in this embodiment judges the accuracy of the first test result by determining whether the volume deviation data of the first test result is less than a preset threshold, and selects whether to perform a second test, it can reduce the occurrence of confusion between red blood cells and platelets by the blood analyzer and improve the accuracy of the blood analyzer.

[0056] Optionally, the blood analyzer also includes a sample preparation module and a sampling module. The sampling module is used to sample the sample tube to obtain a blood sample, and the sample preparation module is used to prepare the blood sample to obtain a first test sample.

[0057] In one embodiment, the first detection module 20 performs a first detection on a portion of the first sample to be tested, and the optical detection module 30 performs a second detection on the remaining first sample to be tested based on optical configuration parameters. Specifically, when the first detection module 20 is the optical detection module 30, the sample to be tested used for the first and second detections can be the same, so that during the second detection, the control module 10 can control the optical detection module 30 to directly detect the first sample, thereby reducing the process steps of re-preparing the sample and improving the speed of blood analysis.

[0058] In another embodiment, the sample preparation module is also used to re-prepare the blood sample to obtain a second test sample; the first detection module 20 is used to perform a first test on the first test sample, and the optical detection module 30 performs a second test on the second test sample based on optical configuration parameters. Specifically, before the optical detection module 30 performs the test, the control module 10 controls the sample preparation module to re-prepare the blood sample to obtain a second test sample. The control module 10 controls the optical detection module 30 to perform the test on the second test sample according to the optical configuration parameters, so as to reduce the influence between different test reagents and improve the accuracy of the blood analyzer.

[0059] Optionally, please see Figure 2 , Figure 2 This is a schematic diagram of another embodiment of the blood analyzer provided in this application. Figure 2 As shown, the optical detection module 30 includes a light emitting unit for emitting laser light, and the optical configuration parameters include the laser power parameters of the light emitting unit; the control module 10 includes a controller, a voltage conversion unit, and a drive circuit unit.

[0060] Specifically, the controller is used to acquire control parameters and generate control signals based on the control parameters, which correspond to the laser power parameters; the voltage conversion unit is connected to the controller and is used to receive the control signals and convert them into drive voltage; the drive circuit unit is connected to the voltage conversion unit and is used to receive the drive voltage and convert it into drive current; wherein, the drive circuit unit is connected to the light emitting unit and drives the light emitting unit to output laser through the drive current, so as to configure the laser power parameters of the optical detection module 30.

[0061] Specifically, the memory of the control module 10 stores control parameters of a digital potentiometer corresponding to the laser power parameters. The controller reads the memory to obtain the control parameters corresponding to the laser power parameters and generates a control signal based on the control parameters, which is then transmitted to the voltage conversion unit. The circuit conversion unit generates a corresponding driving voltage based on the received control parameters and transmits the driving voltage to the driving circuit unit. The driving circuit unit converts the driving voltage into a driving current and transmits the driving current to the light emitting unit, so that the light emitting unit emits laser light according to the acquired driving current, thereby configuring the optical detection module 30 according to the laser power parameters.

[0062] The blood analyzer in this embodiment can control the drive circuit unit to generate a corresponding drive current through the controller, so that the light emission unit emits laser according to the acquired drive current, and the laser power of the real-time optical detection module 30 is adjusted. The structure is simplified and the size is small, which further reduces the cost of the blood analyzer.

[0063] Optionally, the voltage conversion unit includes a reference voltage generation circuit, a laser activation control circuit, and an error amplifier circuit. The reference voltage generation circuit is connected to the controller and is used to receive control parameters to generate a reference voltage based on the control parameters; the laser activation control circuit is connected to the controller and obtains a feedback signal from the controller; the error amplifier circuit is connected to both the reference voltage generation circuit and the laser activation control circuit and is used to convert the reference voltage and the feedback signal into a driving voltage.

[0064] Optionally, the light emitting unit includes an output detection circuit and a laser chip. The laser chip emits laser light according to the driving current, and the output detection circuit acquires the photocurrent of the laser light. The control module 10 also includes a feedback signal circuit, which is connected to the laser activation control circuit and the output detection device. The feedback signal circuit acquires the photocurrent and converts it into a voltage signal. The error amplifier circuit generates the driving voltage based on the voltage signal and a reference signal.

[0065] Understandably, the error amplifier circuit has a first input terminal, a second input terminal, and an output terminal. The first input terminal of the error amplifier circuit is connected to the reference voltage generation circuit, the second input terminal of the error amplifier circuit is connected to the laser activation control circuit, and the output terminal of the error amplifier circuit is connected to the drive circuit unit. The controller sends control parameters to the voltage conversion unit, the reference voltage generation circuit generates a reference voltage according to the control parameters, and inputs the reference voltage to the first input terminal of the error amplifier circuit; simultaneously, the controller generates a control signal in response to the laser activation command, the laser activation control circuit receives the control signal to generate a feedback signal, and inputs the feedback signal to the second input terminal of the error amplifier circuit.

[0066] Simultaneously, the output detection circuit of the optical emission unit acquires the photocurrent output by the laser chip and sends it to the feedback signal circuit. The feedback signal circuit converts the photocurrent into a voltage signal and transmits it to the laser activation control circuit. The laser activation control circuit generates a feedback signal based on the received voltage signal from the feedback signal circuit and the controller's control signal, enabling the error amplifier circuit to generate a drive voltage based on the feedback signal and the reference voltage. After the test is completed, the controller, in response to the received command to stop laser output, shuts off the control signal of the laser activation control circuit, preventing the error amplifier circuit from acquiring the feedback signal from the laser control circuit. The drive circuit unit then stops outputting the drive current and stops emitting laser light.

[0067] In this embodiment, when the controller receives the laser adjustment command, the controller reads the data in the memory to obtain the control parameters corresponding to the adjusted laser power parameters, so that the voltage conversion unit generates a new driving voltage according to the adjusted control parameters, thereby realizing the laser power adjustment of the optical detection module 30. The structure is simplified and the size is small, further reducing the cost of the blood analyzer.

[0068] This application also provides a blood analyzer for animals, which includes a first detection module 20, a control module 10 and an optical detection module 30, for detecting animal blood samples, such as blood samples from dogs, cats and other animals.

[0069] The first detection module 20 is used to detect animal blood samples to obtain a first detection result of the animal blood samples; the control module 10 is used to obtain the optical configuration parameters corresponding to the first detection result, and configure the optical detection module 30 according to the optical configuration parameters; the optical detection module 30 is used to detect animal blood samples based on the configured optical configuration parameters, and obtain a second detection result of the animal blood samples; the control module 10 is also used to obtain the analysis results of the animal blood samples based on the first detection result and the second detection result.

[0070] The first detection module 20 is used to perform impedance detection or optical detection on the animal blood sample according to the animal type of the animal blood sample, or the control module 10 is used to obtain optical configuration parameters according to the animal type of the animal blood sample and the first detection result.

[0071] Specifically, the animal type of the animal blood sample can be information obtained by the blood analyzer through a barcode scanner to identify the identification code of the sample to be tested, or it can be animal type information input by the user through a visual interface. The control module 10 can obtain a range of optical configuration parameters based on the animal type of the animal blood sample. The first detection module 20 performs a first impedance detection or optical detection on the animal blood sample based on the optical configuration parameters within this range. Alternatively, the control module 10 can further select the corresponding optical configuration parameters within this range based on the first detection result.

[0072] Please see Figure 3 , Figure 3 This is a schematic flowchart of an embodiment of the blood analysis method provided in this application. Figure 3 As shown, in this embodiment, the blood analysis method includes the following steps:

[0073] Step S11: Detect the sample to be tested to obtain the first test result of the sample.

[0074] Specifically, in response to a test command, the blood analyzer causes the first detection module 20 to perform a test on the sample and obtain the first test result. The blood analyzer can be connected to a visual interface, through which the user controls the operation of the blood analyzer. For example, the visual interface generates test commands based on user clicks, inputs, and other operations and sends the test commands to the blood analyzer, causing the first detection module 20 to perform a test in response to the test commands.

[0075] Step S12: Obtain the optical configuration parameters corresponding to the first detection result.

[0076] After obtaining the first detection result of the sample to be tested, the optical configuration parameters of the optical detection module 30 are obtained according to the first correspondence between the preset first detection result and the optical configuration parameters.

[0077] Step S13: Perform a second detection on the sample to be tested based on the optical configuration parameters to obtain the second detection result of the sample to be tested.

[0078] The configuration of the optical detection module 30 is adjusted based on the optical configuration parameters to perform a second detection on the sample to be tested and obtain a second detection result. Understandably, the second detection result can correspond to the first detection result; for example, the first and second detection results can be blood cell counts such as red blood cells, platelets, and white blood cells; or, the second detection result can be a result correction parameter for the first detection result, used to correct the first detection result.

[0079] Step S14: Obtain the analysis results of the sample to be tested based on the first and second detection results.

[0080] After obtaining the first detection result from the first detection module 20 and the second detection result from the optical detection module 30, the analysis result of the sample to be tested is obtained based on the first and second detection results. The analysis result of the sample to be tested can be the optical configuration parameters obtained by adjusting the first detection result based on the second detection result, or it can be the analysis result of the sample to be tested using the second detection result as the analysis result. The output content and layout of the analysis result can be adjusted according to user needs; no specific limitations are imposed on the analysis result here.

[0081] In this embodiment, the blood analysis method obtains corresponding optical configuration parameters based on the first detection result of the first detection module 20, so that the optical configuration parameters of the optical detection module 30 correspond to the blood cell size of the sample to be tested, thereby enabling the blood analysis method of this embodiment to adapt to blood cells of various shapes and improve the accuracy of the blood analyzer.

[0082] In one embodiment, the first detection result includes first blood cell parameters of the sample to be tested, and the second detection result includes result correction parameters of the sample to be tested. Step S14 may include the following steps: the control module 10 adjusts the first blood cell parameters based on the result correction parameters, and generates analysis results based on the adjusted first blood cell parameters.

[0083] Specifically, in this embodiment, the first detection result is the first blood cell parameter of the sample to be tested. For example, the first blood cell parameter includes, but is not limited to, the first red blood cell parameter and the second platelet parameter. Based on the first blood cell parameter, the optical configuration parameters of the optical detection module 30 are obtained, and the sample to be tested is detected again based on the optical configuration parameters to obtain the result correction parameter for the sample to be tested. The result correction parameter can be used to indicate the deviation between the first blood cell parameter and the true result. For example, when the result correction parameter is 88%, it indicates that the first blood cell parameter is too large. The adjusted first blood cell parameter can be obtained by multiplying the first blood cell parameter with the result correction parameter. The adjusted first blood cell parameter is closer to the true result, thus improving the accuracy of the blood analysis.

[0084] In one embodiment, the first detection result includes a first blood cell parameter of the sample to be tested, and the second detection result includes a second blood cell parameter of the sample to be tested. Step S13 includes the following steps: the control module 10 adjusts the second blood cell parameter based on the first blood cell parameter, and generates an analysis result based on the adjusted second blood cell parameter.

[0085] Specifically, in this embodiment, the first detection result is the first blood cell parameter of the sample to be tested, and the second detection result is the second blood cell parameter of the sample to be tested. After acquiring the second blood cell parameter, the control module 10 adjusts the second blood cell parameter based on the first blood cell parameter, and generates an analysis result based on the adjusted second blood cell parameter.

[0086] In one optional embodiment, the control module 10 can select a corresponding adjustment method based on the deviation value between the first blood cell parameter and the second blood cell parameter, and adjust the second blood cell parameter according to the selected adjustment method to generate an analysis result; for example, when the deviation value between the first blood cell parameter and the second blood cell parameter is less than a preset threshold, the control module 10 does not adjust the second blood cell parameter and directly generates an analysis result based on the second blood cell parameter, and / or, when the deviation value between the first blood cell parameter and the second blood cell parameter is greater than or equal to the preset threshold, the control module 10 obtains the weighted value of the first blood cell parameter and the second blood cell parameter to generate an analysis result based on the weighted value.

[0087] Furthermore, in any of the above embodiments, the first detection result and the second detection result are used to indicate red blood cell parameters and platelet parameters. The blood analyzer selects optical configuration parameters corresponding to the cell size of the sample to be tested based on the first detection result, so as to correct the reticulocyte parameters based on the first detection result and the second detection result, so as to make the reticulocyte parameters indicated by the analysis result more accurate, thereby improving the accuracy of the blood analysis method.

[0088] For example, the first detection result includes, but is not limited to, red blood cell volume parameters, platelet volume parameters, and reticulocyte parameters. The reticulocyte parameter indicates the number of reticulocytes contained in a preset number of red blood cells; for example, the reticulocyte parameter represents the percentage of reticulocytes in red blood cells. When a blood analyzer analyzes samples from different species or with different morphologies, due to species differences, the blood analyzer may confuse red blood cells and platelets when the red blood cell volume parameters and platelet volume parameters are similar, leading to incorrect red blood cell counting and lower accuracy of the reticulocyte parameter. The blood analyzer of this embodiment selects the optical configuration parameters of the optical detection module 30 based on the first detection result to obtain a second detection result, and generates corresponding analysis results based on the first and second detection results. The reticulocyte parameter in the analysis results is more accurate, thereby improving the accuracy of the blood analysis method.

[0089] Unlike existing technologies, the blood analysis method of this application embodiment obtains the optical configuration parameters of the optical detection module 30 based on the first detection result of the first detection module 20, so that the optical configuration parameters of the optical detection module 30 correspond to the blood cell size of the sample to be tested, so that the blood analysis method can adapt to blood cells of various shapes and improve the accuracy of the blood analyzer.

[0090] The blood analysis method of this application will be further illustrated below through examples.

[0091] The blood analysis method in Example 1 includes the following steps:

[0092] Step 11: The sampling module picks up multiple blood samples and adds one blood sample to the sample preparation module so that the sample preparation module can prepare the blood sample and obtain the first sample to be tested;

[0093] Step 12: The first detection module 20 detects the first sample to be tested to obtain the first detection result of the first sample to be tested, wherein the first detection module 20 is an impedance detection module;

[0094] Step 13: Control module 10 determines whether the first detection result is within the preset range;

[0095] Step 14: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample and uses the first test result as the analysis result;

[0096] Step 15: If the first detection result is not within the preset range, the control module 10 obtains the optical configuration parameters of the optical detection module 30 based on the first detection result;

[0097] Step 16: The sampling module adds another blood sample to the sample preparation module so that the sample preparation module can prepare the other blood sample and obtain the second test sample;

[0098] Step 17: The optical detection module 30 detects the second sample to be tested according to the optical configuration parameters and obtains the second detection result of the second sample to be tested. The optical detection module 30 is the optical detection module 30.

[0099] Step 18: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0100] Understandably, steps 11-18 of this embodiment are specific implementations of steps S11-S13 described above. This blood analysis method obtains the optical configuration parameters of the optical detection module 30 based on the first detection result of the first detection module 20, so that the optical configuration parameters of the optical detection module 30 correspond to the blood cell size of the sample to be tested. This facilitates accurate classification of red blood cells and platelets by the blood analyzer, improving the accuracy of blood analysis. Specifically, before the optical detection module 30 performs detection, the sample preparation module prepares another blood sample. This reduces the influence between the detection reagents when the first detection module 20 and the optical detection module 30 use different detection reagents, improving the accuracy of the blood analyzer.

[0101] The blood analysis method in Example 2 includes the following steps:

[0102] Step 21: The sampling module picks up multiple blood samples and adds one blood sample to the sample preparation module so that the sample preparation module can prepare the blood sample and obtain the first sample to be tested;

[0103] Step 22: The first detection module 20 detects the first sample to be tested to obtain the first detection result of the first sample to be tested, wherein the first detection module 20 is an optical detection module 30;

[0104] Step 23: Control module 10 determines whether the first detection result is within the preset range;

[0105] Step 24: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample and uses the first test result as the analysis result;

[0106] Step 25: If the first detection result is not within the preset range, the control module 10 obtains the optical configuration parameters of the optical detection module 30 based on the first detection result;

[0107] Step 26: The sampling module adds another blood sample to the sample preparation module so that the sample preparation module can prepare the other blood sample and obtain the second test sample;

[0108] Step 27: The optical detection module 30 detects the second sample to be tested according to the optical configuration parameters and obtains the second detection result of the second sample to be tested. The optical detection module 30 is the optical detection module 30.

[0109] Step 28: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0110] The blood analysis method in Example 3 includes the following steps:

[0111] Step 31: The sampling module picks up multiple blood samples and adds one blood sample to the sample preparation module so that the sample preparation module can prepare the blood sample and obtain the first sample to be tested;

[0112] Step 32: The first detection module 20 detects the first sample to be tested to obtain the first detection result of the first sample to be tested, wherein the first detection module 20 is an impedance detection module;

[0113] Step 33: Control module 10 determines whether the first detection result is within the preset range;

[0114] Step 34: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample and uses the first test result as the analysis result;

[0115] Step 35: If the first detection result is not within the preset range, the control module 10 obtains the optical configuration parameters of the optical detection module 30 based on the first detection result;

[0116] Step 36: The optical detection module 30 detects the first sample to be tested according to the optical configuration parameters and obtains the second detection result of the first sample to be tested. The optical detection module 30 is the optical detection module 30.

[0117] Step 37: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0118] Understandably, steps 31-37 of this embodiment are specific implementations of steps S11-S13 above. The optical detection module 30 detects the first sample to be tested, eliminating the need for the sample preparation module to prepare the sample again, thus improving the efficiency of blood analysis.

[0119] The blood analysis method in Example 4 includes the following steps:

[0120] Step 41: The sampling module picks up multiple blood samples and adds one blood sample to the sample preparation module so that the sample preparation module can prepare the blood sample and obtain the first sample to be tested;

[0121] Step 42: The first detection module 20 detects the first sample to be tested to obtain the first detection result of the first sample to be tested, wherein the first detection module 20 is an optical detection module 30;

[0122] Step 43: Control module 10 determines whether the first detection result is within the preset range;

[0123] Step 44: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample and uses the first test result as the analysis result;

[0124] Step 45: If the first detection result is not within the preset range, the control module 10 obtains the optical configuration parameters of the optical detection module 30 based on the first detection result;

[0125] Step 46: The optical detection module 30 detects the first sample to be tested according to the optical configuration parameters and obtains the second detection result of the first sample to be tested. The optical detection module 30 is the optical detection module 30.

[0126] Step 47: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0127] The blood analysis method in Example 5 includes the following steps:

[0128] Step 51: The sampling module picks up multiple blood samples and adds one blood sample to the sample preparation module so that the sample preparation module can prepare the blood sample and obtain the first sample to be tested;

[0129] Step 52: The first detection module 20 detects the first sample to be tested to obtain the first detection result of the first sample to be tested, wherein the first detection module 20 is an impedance detection module;

[0130] Step 53: The control module 10 obtains the optical configuration parameters of the optical detection module 30 based on the first detection result;

[0131] Step 54: The optical detection module 30 detects the first sample to be tested according to the optical configuration parameters and obtains the second detection result of the first sample to be tested. The optical detection module 30 is the optical detection module 30.

[0132] Step 55: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0133] Understandably, steps 51-55 of this embodiment are specific implementations of steps S11-S13 above. The blood analysis method of this embodiment performs two tests on the first test sample through the impedance detection module and the optical detection module 30. Before using the optical detection module 30 for testing, the optical configuration parameters of the optical detection module 30 are adjusted according to the first test result of the impedance detection module, so that the optical configuration parameters of the optical detection module 30 correspond to the blood cell size of the sample to be tested, thereby improving the accuracy of the analysis results.

[0134] The blood analysis method in Example 6 includes the following steps:

[0135] Step 61: The sampling module picks up multiple blood samples and adds one blood sample to the sample preparation module so that the sample preparation module can prepare the blood sample and obtain the first sample to be tested;

[0136] Step 62: The first detection module 20 detects the first sample to be tested to obtain the first detection result of the first sample to be tested, wherein the first detection module 20 is an impedance detection module;

[0137] Step 63: The control module 10 obtains the optical configuration parameters of the optical detection module 30 based on the first detection result;

[0138] Step 64: The sampling module adds another blood sample to the sample preparation module so that the sample preparation module can prepare the other blood sample and obtain the second test sample;

[0139] Step 65: The optical detection module 30 detects the second sample to be tested according to the optical configuration parameters and obtains the second detection result of the second sample to be tested. The optical detection module 30 is the optical detection module 30.

[0140] Step 66: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0141] The blood analysis method in Example 7 includes the following steps:

[0142] Step 71: The sampling module adds the blood sample to the sample preparation module so that the sample preparation module can prepare the blood sample and obtain the sample to be tested;

[0143] Step 72: The first detection module 20 detects the sample to be tested to obtain the first detection result of the sample to be tested. The first detection module 20 is an impedance detection module or an optical detection module 30.

[0144] Step 73: Control module 10 determines whether the first detection result is within the preset range;

[0145] Step 74: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample and uses the first test result as the analysis result;

[0146] Step 75: If the first detection result is not within the preset range, the control module 10 generates a warning message and sends the warning message to the visualization interface;

[0147] Step 76: The control module 10 receives the test command returned from the visualization interface and obtains the optical configuration parameters of the optical detection module 30 based on the first detection result;

[0148] Step 77: The optical detection module 30 detects the sample to be tested according to the optical configuration parameters and obtains the second detection result of the sample to be tested. The optical detection module 30 is the optical detection module 30.

[0149] Step 78: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0150] Understandably, steps 71-78 of this embodiment are specific implementations of steps S11-S13 above. When the first detection result is not within the preset range, the control module 10 of this embodiment will generate a warning message and send the warning message to the visualization interface so that the user can choose whether to perform a second detection through the visualization interface. After receiving the test instruction returned from the visualization interface, the control module 10 controls the optical detection module 30 to perform a second detection. Since the user determines whether the first detection result is abnormal, repeated testing due to abnormal judgment errors is avoided, thereby improving the efficiency of blood analysis.

[0151] The blood analysis method in Example 8 includes the following steps:

[0152] Step 81: The sampling module picks up multiple blood samples and adds two blood samples to the sample preparation module, so that the sample preparation module can prepare the two blood samples and obtain the first test sample and the second test sample.

[0153] Step 82: The impedance detection module detects the first sample under test to obtain the impedance detection result of the first sample under test;

[0154] Step 83: The second optical detection module 30 detects the second sample to be tested to obtain the optical detection result of the second sample to be tested;

[0155] Step 84: The control module 10 obtains the first detection result based on the impedance detection result and the optical detection result, and determines whether the first detection result is within the preset range;

[0156] Step 85: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample;

[0157] Step 86: If the first detection result is not within the preset range, the control module 10 obtains the optical configuration parameters of the first optical detection module 30 based on the first detection result;

[0158] Step 87: The sampling module adds another blood sample to the sample preparation module so that the sample preparation module can prepare the other blood sample and obtain the third sample to be tested;

[0159] Step 88: The first optical detection module 30 detects the third sample to be tested according to the optical configuration parameters and obtains the second detection result of the third sample to be tested;

[0160] Step 89: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0161] Understandably, steps 81-89 in this embodiment are specific implementations of steps S11-S13 above. Since the first optical detection module 30 in this embodiment uses optical detection methodology for detection, in order to reduce the detection deviation between the optical detection module 30 and the impedance detection module due to the difference in detection methodology, the control module 10 obtains the first detection result through the impedance detection result and the optical detection result of the sample to be tested, so as to ensure that the control module 10 can select appropriate optical configuration parameters according to the first detection result and improve the accuracy of blood analysis.

[0162] In this embodiment, the control module 10 generates a warning message when the first detection result is outside the preset range and sends the warning message to the visualization interface so that the user can choose whether to perform a second detection through the visualization interface. After receiving the test instruction returned from the visualization interface, the control module 10 controls the optical detection module 30 to perform a second detection. Since the user determines whether the first detection result is abnormal, repeated testing due to abnormal judgment errors is avoided, thereby improving the efficiency of blood analysis.

[0163] The blood analysis method in Example 9 includes the following steps:

[0164] Step 91: The sampling module picks up multiple blood samples and adds two blood samples to the sample preparation module, so that the sample preparation module can prepare the two blood samples and obtain the first test sample and the second test sample.

[0165] Step 92: The impedance detection module detects the first sample to be tested to obtain the impedance detection result of the first sample to be tested, and the second optical detection module 30 detects the second sample to be tested to obtain the optical detection result of the second sample to be tested.

[0166] Step 93: The control module 10 obtains the first detection result based on the impedance detection result and the optical detection result, and determines whether the first detection result is within the preset range;

[0167] Step 94: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample;

[0168] Step 95: If the first detection result is not within the preset range, the control module 10 generates a warning message and sends the warning message to the visualization interface;

[0169] Step 96: The control module 10 receives the test command returned from the visualization interface and obtains the optical configuration parameters of the first optical module based on the first detection result;

[0170] Step 97: The sampling module adds another blood sample to the sample preparation module so that the sample preparation module can prepare the other blood sample and obtain the third sample to be tested;

[0171] Step 98: The first optical detection module 30 detects the third sample to be tested according to the optical configuration parameters and obtains the second detection result of the third sample to be tested;

[0172] Step 99: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0173] The blood analysis method of Example 10 includes the following steps:

[0174] Step 101: The sampling module picks up multiple blood samples and adds two blood samples to the sample preparation module, so that the sample preparation module can prepare the two blood samples and obtain the first test sample and the second test sample.

[0175] Step 102: The impedance detection module detects the first sample under test to obtain the impedance detection result of the first sample under test;

[0176] Step 103: The second optical detection module 30 detects the second sample to be tested to obtain the optical detection result of the second sample to be tested;

[0177] Step 104: The control module 10 obtains the first detection result based on the impedance detection result and the optical detection result, and determines whether the first detection result is within the preset range;

[0178] Step 105: If the first test result is within the preset range, the control module 10 controls the sampling module to clear the blood sample;

[0179] Step 106: If the first detection result is not within the preset range, the control module 10 obtains the optical configuration parameters of the first optical detection module 30 based on the first detection result;

[0180] Step 107: The first optical detection module 30 detects the second sample to be tested according to the optical configuration parameters and obtains the second detection result of the second sample to be tested;

[0181] Step 108: The control module 10 obtains the analysis results of the sample to be tested based on the first detection result and the second detection result.

[0182] Please see Figure 4 , Figure 4 This is a schematic diagram of another embodiment of the blood analyzer provided in this application. Figure 4 As shown, the blood analyzer 100 includes a processor 101 and a memory 102 connected to the processor 101. The memory 102 stores program data, and the processor 101 retrieves the program data stored in the memory 102 to execute the blood analysis method described above.

[0183] Optionally, in one embodiment, the processor 101 is used to execute program data to implement the following method: to detect the sample to be tested to obtain a first detection result of the sample to be tested; to obtain optical configuration parameters corresponding to the first detection result; to perform a second detection on the sample to be tested based on the optical configuration parameters to obtain a second detection result of the sample to be tested; and to obtain an analysis result of the sample to be tested based on the first detection result and the second detection result.

[0184] The processor 101 can also be referred to as a CPU (Central Processing Unit). The processor 101 may be an electronic chip with signal processing capabilities. The processor 101 can also be a general-purpose processor, a digital signal processor (DSP), an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or other programmable logic devices, discrete gate or transistor logic devices, or discrete hardware components. A general-purpose processor can be a microprocessor or any conventional processor.

[0185] The memory 102 can be a memory module, TF card, etc., and can store all the information in the blood analyzer 100, including the raw input data, computer program, intermediate running results, and final running results. It stores and retrieves information according to the location specified by the processor 101. With the memory 102, the blood analyzer 100 has a memory function and can ensure normal operation. The memory 102 of the blood analyzer 100 can be classified according to its purpose as main memory (RAM) and auxiliary memory (external memory), or it can be classified as external memory and internal memory. External memory is usually magnetic media or optical discs, which can store information for a long time. RAM refers to the storage component on the motherboard, used to store currently executing data and programs, but it is only used for temporary storage of programs and data; the data will be lost when the power is turned off.

[0186] The above description is merely an embodiment of this application and does not limit the patent scope of this application. Any equivalent structural or procedural transformations made using the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this application.

Claims

1. A blood analyzer, characterized in that, The blood analyzer is used to perform blood analysis based on the size of blood cell samples from different species or with different morphologies, and the blood analyzer includes: The first detection module is used to perform a first detection on the sample to be tested in order to obtain the first detection result of the sample to be tested. The control module is used to acquire the optical configuration parameters corresponding to the first detection result and configure the optical detection module according to the optical configuration parameters. The optical detection module is used to perform a second detection on the sample to be tested based on the configured optical configuration parameters, and to obtain a second detection result of the sample to be tested. The control module is also used to obtain the analysis results of the sample to be tested based on the first detection result and the second detection result; The first detection module includes an impedance detection module and / or the optical detection module; The control module is used to control the impedance detection module to detect the sample under test in order to obtain the impedance detection result of the sample under test. And / or, the control module controls the optical detection module to detect the sample to be tested in order to obtain the optical detection result of the sample to be tested; The control module is also used to obtain the animal type of the test sample, the animal type including a first animal type and a second animal type, wherein the red blood cell size of the test sample of the first animal type is larger than the red blood cell size of the test sample of the second animal type; The control module is further configured to control the impedance detection module to perform a first detection on the sample under test in response to the sample being the first animal type, and the control module is further configured to control the optical detection module to perform a first detection on the sample under test in response to the sample being the second animal type, so as to obtain the first detection result.

2. The blood analyzer according to claim 1, characterized in that, The optical configuration parameters include at least one of the following: laser power parameters of the optical detection module, receiver gain parameters, sample flow parameters, and spot size parameters.

3. The blood analyzer according to claim 1, characterized in that, The control module is further configured to acquire the optical configuration parameters corresponding to the first detection result when it is determined that the first detection result is not within a preset range; or, The first detection module is the optical detection module. The control module is used to generate a warning message when it is determined that the first detection result is not within the preset range, and send the warning message to the visualization interface. The control module is also used to receive confirmation information returned by the visualization interface, so as to obtain the optical configuration parameters based on the first detection result when the confirmation information includes a test instruction.

4. The blood analyzer according to claim 3, characterized in that, The preset range includes a preset threshold set based on the volume deviation of red blood cells and platelets. The control module is also used to obtain the volume deviation data of red blood cells and platelets of the sample to be tested based on the first detection result; and when the volume deviation data is less than the preset threshold, it is determined that the first detection result is not in the preset range.

5. The blood analyzer according to claim 1, characterized in that, The blood analyzer also includes a sample preparation module and a sampling module. The sampling module is used to sample the sample tube to obtain a blood sample, and the sample preparation module is used to prepare the blood sample to obtain a first test sample. The first detection module is used to perform a first detection on a portion of the first sample to be tested, and the optical detection module performs a second detection on the remaining portion of the first sample to be tested based on the optical configuration parameters, or... The sample preparation module is also used to re-prepare the blood sample to obtain a second sample to be tested; the first detection module is used to perform a first test on the first sample to be tested, and the optical detection module performs a second test on the second sample to be tested based on the optical configuration parameters.

6. The blood analyzer according to claim 1, characterized in that, The optical detection module includes a light emitting unit for emitting laser light, and the optical configuration parameters include the laser power parameters of the light emitting unit; the control module includes: A controller is used to acquire control parameters and generate control signals based on the control parameters, wherein the control parameters correspond to the laser power parameters; A voltage conversion unit, connected to the controller, is used to receive the control signal and convert the control signal into a drive voltage; A driving circuit unit, connected to the voltage conversion unit, is used to receive the driving voltage and convert the driving voltage into a driving current; The driving circuit unit is connected to the optical emitting unit, and the driving circuit unit drives the optical emitting unit to output laser through the driving current, so as to configure the laser power parameters of the optical detection module.

7. A blood analyzer for animals, characterized in that, include: The first detection module is used to detect animal blood samples to obtain the first detection result of the animal blood samples; The control module is used to acquire the optical configuration parameters corresponding to the first detection result and configure the optical detection module according to the optical configuration parameters. The optical detection module is used to detect the animal blood sample based on the configured optical configuration parameters and obtain a second detection result of the animal blood sample. The control module is also used to obtain the analysis results of the animal blood sample based on the first detection result and the second detection result; Wherein, the first detection module is used to perform impedance detection or optical detection on the animal blood sample according to the animal type of the animal blood sample, or the control module is used to obtain the optical configuration parameters according to the animal type of the animal blood sample and the first detection result; The first detection module includes an impedance detection module and / or the optical detection module; The control module is used to control the impedance detection module to detect the sample under test in order to obtain the impedance detection result of the sample under test; and / or, the control module controls the optical detection module to detect the sample under test in order to obtain the optical detection result of the sample under test. The control module is also used to obtain the animal type of the test sample, the animal type including a first animal type and a second animal type, wherein the red blood cell size of the test sample of the first animal type is larger than the red blood cell size of the test sample of the second animal type; The control module is further configured to control the impedance detection module to perform a first detection on the sample under test in response to the sample being the first animal type, and the control module is further configured to control the optical detection module to perform a first detection on the sample under test in response to the sample being the second animal type, so as to obtain the first detection result.

8. A blood analysis method, characterized in that, Applied to a blood analyzer as described in any one of claims 1-6 or an animal blood analyzer as described in claim 7, comprising: The sample to be tested is tested to obtain a first test result for the sample to be tested; Obtain the optical configuration parameters corresponding to the first detection result; Based on the optical configuration parameters, a second detection is performed on the sample to be tested to obtain a second detection result for the sample to be tested. The analysis results of the sample to be tested are obtained based on the first detection result and the second detection result.

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