Material mixing system and method based on aseptic environment

Abstract

The present application provides a material mixing system and method based on a sterile environment, which belongs to the field of material sterilization and mixing technology. The system sets two material conveying parts and a material mixing part, so that the two materials can flow to the material mixing part synchronously for mixing, and after the mixing is completed, the filling part can be directly filled once to complete the operation; by setting a booster part, the air pressure in the material mixing chamber of the material mixing part is higher than the external air pressure, which can avoid or reduce the invasion of bacteria into the mixed materials; by setting a steam conveying part, the steam channel of the steam conveying part is connected to the driving pump in the material conveying part. When the driving pump in the material conveying part is detected to be blocked, the steam conveying part can be controlled to supply the generated steam to the corresponding driving pump, and the driving pump can be flushed with high temperature in time, so that the material attached to the driving pump is softened and detached, thereby improving the flushing effect of the driving pump.

Description

Technical Field

[0001] The present application relates to the technical field of material sterilization and mixing, and in particular to a material mixing system and method based on a sterile environment. Background Art

[0002] In the production process of many industries, material mixing is a key step, which aims to achieve accurate proportions and uniform combination of multiple components to meet the performance requirements and specifications of the final product. These industries include but are not limited to food, chemical, pharmaceutical, daily chemical products, biotechnology, etc. They all face high demands for mixing uniformity, aseptic control of the production process and efficient automation.

[0003] The demand for material mixing stems from the market's pursuit of product diversification and strict standards for product performance. For example, in the production of fruit juice drinks, in order to increase the taste and nutritional value of the product, it is often necessary to mix the juice with fruit particles, fiber or other nutrient ingredients; in the chemical industry, the mixing of multiple raw materials can produce chemicals with specific properties, such as pigments, resins, etc.

[0004] In traditional material mixing technology, especially for the mixing of materials containing multiple ingredients such as fruit particles, colloids, powders, liquids, etc., the secondary filling method is generally adopted, that is, the first sterilized material is first injected into the package, and then the second sterilized material is injected. However, during the secondary or even multiple filling process, the chance of material contact with air is greatly increased, and there is a risk of bacteria entering the package, which is difficult to meet the mixing requirements of materials with extremely high mixing accuracy and hygiene requirements. In addition, the traditional mixing equipment has a low degree of automation, resulting in low production efficiency and difficulty in meeting the needs of large-scale production. Summary of the invention

[0005] The purpose of the present application is to provide a material mixing system and method based on a sterile environment to solve at least one of the above problems.

[0006] In a first aspect of the present application, a material mixing system based on a sterile environment is provided, the system comprising:

[0007] A first material conveying part, used for storing and conveying a first material, comprises a first material channel, a first flow valve arranged in the first material channel, a first driving pump, and a first flow sensor located downstream of the first flow valve;

[0008] A second material conveying part, used for storing and conveying a second material, comprises a second material channel communicated with the first material channel, a second flow valve arranged in the second material channel, a second driving pump, and a second flow sensor located downstream of the second flow valve;

[0009] A material mixing section, used for storing and mixing the first material and the second material conveyed to form a mixed material;

[0010] A pressurizing part, used for delivering air pressure to the material mixing part, so that the air pressure in the material mixing chamber of the material mixing part is higher than the external air pressure;

[0011] A filling part, used for filling the mixed material conveyed by the material mixing part;

[0012] A steam delivery part, comprising a steam generating part, a first flushing channel, and a second flushing channel, wherein the first flushing channel and the second flushing channel are in communication with the steam generating part, the first driving pump is further arranged in the first flushing channel, and the second driving pump is further arranged in the second flushing channel;

[0013] The control component is used to detect whether the first drive pump and the second drive pump are blocked based on the data measured by the first flow sensor and the second flow sensor. When the first drive pump is detected to be blocked, the steam in the first flushing channel is controlled to flush the first drive pump. When the second drive pump is detected to be blocked, the steam in the second flushing channel is controlled to flush the second drive pump.

[0014] Optionally, the control component is also used to control the first driving pump to reverse when blockage is detected in the first driving pump, and to guide the steam in the first flushing channel to flush the first driving pump during the reversal; and to control the first flow valve and the second flow valve to close to pause the flow of the first material and the second material to the material mixing section.

[0015] Optionally, the first material conveying section further includes a first storage tank for storing the first material, a first capacity sensor arranged in the first storage tank for measuring the capacity of the first material, and a first air pressure sensor arranged in the first material channel and upstream of the first driving pump.

[0016] Optionally, the second material conveying section further includes a second storage tank for storing a second material, a second capacity sensor arranged in the second storage tank for measuring the capacity of the second material, and a second air pressure sensor arranged in the second material channel and upstream of the second driving pump.

[0017] Optionally, the material mixing part includes a mixing channel and a material mixing tank, the material mixing tank includes a material inlet, a material outlet, an air pressure inlet, a material mixing chamber, and a stirring part located in the material mixing chamber, the first end of the mixing channel is connected to the material inlet, and the second end is connected to the second material channel.

[0018] Optionally, the pressurizing unit includes a gas compressor, a gas channel, a gas pressure valve arranged on the gas channel, and a third gas pressure sensor, and the gas channel connects the gas compressor and the gas pressure inlet.

[0019] Optionally, the steam delivery part further includes a first protection channel and a second protection channel, and the first protection channel and the second protection channel are connected to the steam generation part.

[0020] Optionally, the first protection channel and the first material channel are connected at a first intersection through a first control valve; when the first control valve is in a first state, the first material channel is connected and the first protection channel is disconnected; when the first control valve is in a second state, the first material channel is disconnected and the first protection channel is connected.

[0021] Optionally, the second protection channel is connected to the second material channel through a second control valve at the second intersection. When the second control valve is in a first state, the second material channel is connected and the second protection channel is disconnected. When the second control valve is in a second state, the second material channel is disconnected and the second protection channel is connected.

[0022] Optionally, the first control valve is a first cross valve, the second control valve is a second cross valve, the first material conveying portion further includes a first reflux channel, and the second material conveying portion further includes a second reflux channel.

[0023] Optionally, the first material channel is connected through the first channel of the first cross valve, and the first protection channel is connected through the second channel of the first cross valve. The first material conveying part also includes a first reflux channel connected to one end of the first channel. When the first cross valve is in a first state, the first channel is connected and the second channel is disconnected. When the first cross valve is in a second state, the first channel is disconnected and the second channel is connected. The first material enters the first reflux channel from upstream of the first intersection of the first material channel.

[0024] Optionally, the second material channel is connected through the third channel of the second cross valve, the second protection channel is connected through the fourth channel of the second cross valve, the second material conveying part also includes a second reflux channel connected to one end of the third channel, the other end of the third channel is connected to the first material channel and the second material channel, when the second cross valve is in a first state, the third channel is connected and the fourth channel is disconnected, when the second cross valve is in a second state, the third channel is disconnected and the fourth channel is connected, and the second material enters the second reflux channel from upstream of the second intersection of the second material channel.

[0025] Optionally, the steam delivery section further includes a first auxiliary channel connected in parallel with the first protection channel and a second auxiliary channel connected in parallel with the second protection channel.

[0026] Optionally, the first protection channel and the first auxiliary channel are in a U-shape, and when the first protection channel is in a disconnected state, the first auxiliary channel is connected, and when the first protection channel is in a connected state, the first auxiliary channel is disconnected.

[0027] Optionally, the second protection channel and the second auxiliary channel are in a U-shape, and when the second protection channel is in a disconnected state, the second auxiliary channel is connected, and when the second protection channel is in a connected state, the second auxiliary channel is disconnected.

[0028] In a second aspect of the present application, a material mixing method based on a sterile environment is provided, and the method is applied to the material mixing system based on a sterile environment described in any one of the present applications, and the method comprises:

[0029] Acquire a real-time rotation speed of a first driving pump and a first flow rate set of a first material in a first material channel in a unit time length;

[0030] Obtaining a standard flow rate that matches the real-time rotation speed;

[0031] Calculating a deviation flow rate set of the first flow rate set relative to the standard flow rate;

[0032] determining whether a first driving pump in the first material channel is blocked based on the deviation flow rate set;

[0033] When there is a blockage, the flow of the first material and the second material to the material mixing tank is suspended, and the steam in the first flushing channel is conducted to flush the first driving pump.

[0034] Optionally, the method further includes:

[0035] Acquire a third air pressure of the material mixing chamber measured by a third air pressure sensor under the unit time length;

[0036] Calculating a corresponding average air pressure based on the third air pressure;

[0037] The obtaining of the standard flow rate matching the real-time rotation speed comprises: calculating the average rotation speed in the unit time length according to the real-time rotation speed, and obtaining the standard flow rate matching the average rotation speed and the average air pressure.

[0038] Optionally, the method further includes: obtaining a first material flow rate of a first material in the first storage tank under the unit time length; obtaining a second material flow rate of a second material in the second storage tank under the unit time length;

[0039] The determining whether the first driving pump in the first material channel is blocked based on the deviation flow rate set includes: determining whether the first driving pump in the first material channel is blocked based on the first material flow rate, the second material flow rate and the deviation flow rate set.

[0040] Optionally, the determining whether the first driving pump in the first material channel is blocked based on the first material flow rate, the second material flow rate and the deviation flow rate set includes:

[0041] Calculating the real-time mixing ratio under the unit time length based on the first material flow rate and the second material flow rate;

[0042] Calculating a ratio deviation between the real-time mixing ratio and a preset standard mixing ratio;

[0043] Calculate the corresponding first quartile, second quartile and third quartile according to the deviation flow rate set;

[0044] It is determined whether the first driving pump is blocked based on one or more parameters among the first quartile, the second quartile, the third quartile, and the proportional deviation.

[0045] The material mixing system and method based on a sterile environment in the present application, by setting up two material conveying sections and a material mixing section, allows the two materials to flow synchronously to the material mixing section for mixing, and after the mixing is completed, it can be directly filled once to the filling section to complete the operation. Compared with the traditional secondary filling, it saves the number of material mixing and filling times and improves the operation efficiency.

[0046] In addition, by setting up a booster part, the generated air pressure is transmitted to the material mixing part, so that the air pressure in the material mixing chamber is higher than the external air pressure, which can avoid or reduce the invasion of bacteria into the mixed materials, so that the materials are mixed in a sterile environment, thereby improving the mixing quality of the materials.

[0047] Furthermore, by setting up a steam conveying part, the steam channel of the steam conveying part is also connected to the driving pump in the material conveying part. In this way, when the control component detects that the driving pump in the material conveying part is blocked according to the relevant sensor, the steam conveying part can be controlled to supply the generated steam to the corresponding driving pump, and the driving pump can be flushed with high temperature in time, so that the material attached to the driving pump is softened and detached, thereby improving the flushing effect of the driving pump. BRIEF DESCRIPTION OF THE DRAWINGS

[0048] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope of the present application.

[0049] Figure 1 It is a schematic diagram of the structure of a material mixing system based on a sterile environment in one embodiment;

[0050] Figure 2 This is a schematic diagram of the structure of a material mixing tank in one embodiment;

[0051] Figure 3 is a schematic structural diagram of a first control valve in an embodiment;

[0052] Figure 4 is a schematic structural diagram of a second control valve in one embodiment;

[0053] Figure 5 The figure is a schematic flow chart of a material mixing method in a sterile environment in one embodiment;

[0054] Figure 6 It is a schematic diagram of a flow chart for determining whether a first driving pump in the first material channel is blocked based on the first material flow rate, the second material flow rate and the deviation flow rate set in one embodiment.

[0055] Among them, 101, the first driving pump; 102, the first flow valve; 103, the first control valve; 110, the first material channel; 120, the first storage tank; 130, the first reflux channel; 201, the second driving pump; 202, the second flow valve; 203, the second control valve; 210, the second material channel; 220, the second storage tank; 230, the second reflux channel; 310, the mixing channel; 320, the material mixing tank; 321, the material inlet; 322, the air pressure inlet; 323, the material outlet; 324, the material mixing chamber; 325-1, the stirring motor; 325-2, the stirring shaft; 325-3, the blade; 326, the flushing inlet; 327, the soft water injection port; 328, the interlayer space; 410, the gas channel; 501, the third driving pump; 502, the third flow valve; 510, filling channel; 520, filling tank; 601, steam driven pump; 602, steam control valve; 603, steam main pipeline; 605, steam generating part; 610, first flushing channel; 611, first flushing valve; 612, first steam trap; 620, second flushing channel; 621, second flushing valve; 622, second steam trap; 630, first protection channel; 631, third steam trap; 635, first auxiliary channel; 636, first auxiliary valve; 640, second protection channel; 641, fourth steam trap; 645, second auxiliary channel; 646, second auxiliary valve; 710, heating pipe; 720, flushing pipe; 730, soft water pipe; A1, first port; B1, second port; C1, third port; D1, fourth port; A2, fifth port; B2, sixth port; C2, seventh port; D2, eighth port; A1-B1, first channel; C1-D1, second channel; A2-B2, third channel; C2-D2, fourth channel. DETAILED DESCRIPTION

[0056] In order to make the purpose, technical solution and advantages of the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0057] All terms (including technical and scientific terms) used in this application have the meanings commonly understood by those skilled in the art, unless otherwise defined. It should be noted that the terms used here should be interpreted as having a meaning consistent with the context of this specification, and should not be interpreted in an idealized or overly rigid manner.

[0058] For example, the term "first", "second" etc. used in the present application can be used to describe various elements in this article, but these elements are not limited by these terms. These terms are only used to distinguish the first element from another element. For example, without departing from the scope of the present application, the first drive pump can be referred to as the second drive pump, and similarly, the second drive pump can be referred to as the first drive pump. Both the first drive pump and the second drive pump are drive pumps, but they are not the same drive pump.

[0059] For another example, the terms “include”, “comprising”, etc. used in this application indicate the existence of features, steps, operations and / or components, but do not exclude the existence or addition of one or more other features, steps, operations or components.

[0060] In one embodiment, a material mixing system based on a sterile environment is provided, the system comprising: a first material conveying part, a second material conveying part, a material mixing part, a pressurizing part, a filling part, a steam conveying part and a control component.

[0061] Combination Figure 1 As shown, the first material conveying part is used to store and convey the first material, and includes a first material channel 110, a first flow valve 102, a first driving pump 101, and a first flow sensor; and also includes a first storage tank 120, a first capacity sensor, and a first air pressure sensor. Among them, the first flow valve 102, the first driving pump 101, the first flow sensor, and the first air pressure sensor are all arranged in the first material channel 110. Optionally, in terms of the flow direction of the first material in the first material channel, the first flow sensor is located downstream of the first driving pump, and the first air pressure sensor is located upstream of the first driving pump. The order of the first flow valve and the first driving pump may not be limited, for example, the first driving pump may be arranged downstream of the first flow valve, and the first driving pump may be a centrifugal pump.

[0062] The first storage tank 120 may be a sterile tank for storing the first material. The first storage tank is provided with a first material outflow port, which is connected to the first material channel, so that the first material flows from the first storage tank through the first material outflow port to the first logistics channel. The first capacity sensor may be arranged in the first storage tank, and is used to measure the first material capacity of the material in the first storage tank in real time. The capacity may be volume or weight, etc. The first capacity sensor may be a corresponding liquid level sensor, a gravity sensor, etc., and the remaining volume of the first material therein may be calculated through the measured liquid level height or weight.

[0063] The second material conveying part is used to store and convey the second material, and includes a second material channel 210, a second flow valve 202, a second driving pump 201, and a second flow sensor; and also includes a second storage tank 220, a second capacity sensor, and a second air pressure sensor. The second flow valve 202, the second driving pump 201, the second flow sensor, and the second air pressure sensor are all arranged in the second material channel 210. In terms of the flow direction of the second material in the second material channel, the second flow sensor is located downstream of the second driving pump, and the second air pressure sensor is located upstream of the second driving pump. The order of the second flow valve and the second driving pump may not be limited, for example, the second driving pump may be arranged downstream of the second flow valve, and the second driving pump may be a centrifugal pump.

[0064] The second storage tank 220 may be a sterile tank for storing the second material. The second storage tank is provided with a second material outflow port, which is connected to the second material channel, so that the second material flows from the second storage tank to the second logistics channel through the second material outflow port. The second capacity sensor may be provided in the second storage tank for measuring the second material capacity of the material in the second storage tank in real time. The second capacity sensor may be a corresponding liquid level sensor, a gravity sensor, etc., and the remaining volume of the second material therein may be calculated through the measured liquid level height or weight.

[0065] The material mixing section is used to store and mix the first material and the second material conveyed to form a mixed material. Specifically, the mixed material formed by mixing the first material and the second material can be stored and conveyed, and includes a mixing channel 310 and a material mixing tank 320. The material mixing tank 320 can also be a sterile tank, and the material mixing tank includes a material inlet 321, a material outlet 323, an air pressure inlet 322, a material mixing chamber 324, and a stirring section in the material mixing chamber. The first end of the mixing channel 310 is connected to the material inlet 321, and the second end is connected to the second material channel 210. Specifically, the second material channel 210 is also connected to the first material channel 110, and the second material channel 210 and the first material channel 110 are connected to the second end of the mixing channel 310 after merging. The material outlet 323 can be set at the bottom of the material mixing tank to facilitate the outflow of the mixed material.

[0066] A third capacity sensor is also provided in the material mixing tank 320, through which the third material capacity in the material mixing chamber can be detected in real time. The third capacity sensor can be a gravity sensor or a liquid level sensor.

[0067] The filling part includes a filling tank 520, a filling channel 510, a third driving pump 501 arranged in the filling channel, a third flow valve 502 and a third flow sensor, and the filling channel connects the filling tank 520 and the material outlet 323. Among them, the third flow sensor is located downstream of the third driving pump 501, and the upstream and downstream positions of the third flow valve 502 and the third driving pump 501 may not be limited.

[0068] The pressurizing part is used to deliver air pressure to the material mixing part, so that the air pressure in the material mixing chamber of the material mixing part is higher than the external air pressure. The pressurizing part includes a gas compressor, a gas channel 410, an air pressure valve arranged on the gas channel, and a third air pressure sensor. The gas channel 410 connects the gas compressor and the air pressure inlet 322. Among them, the third air pressure sensor can measure the third air pressure in the gas channel 410 and the material mixing chamber 324. During the material mixing and filling process, the gas generated by the pressurizing part enters the material mixing chamber 324 from the air pressure inlet 322 after passing through the gas channel 410, so that the air pressure in the material mixing chamber 324 is higher than the external air pressure, thereby reducing the invasion of bacteria into the material mixing chamber 324.

[0069] The control component can obtain the data detected by each sensor in the present application, and can control the opening of each valve and the speed of the pump, so that the first material and the second material enter the material mixing part to form a mixture according to a preset standard mixing ratio, and when an abnormality is detected, the opening of the relevant valve or the speed of the pump is controlled in time to repair the relevant abnormality or suspend material mixing.

[0070] Specifically, the control component can control the opening of the first flow valve, the second flow valve, the third flow valve, and the air pressure valve according to the data measured by the first flow sensor, the second flow sensor, the third flow sensor, and the third air pressure sensor, and control the rotational speed of the first drive pump, the second drive pump, and the third drive pump, so that the first material and the second material are stirred and mixed in accordance with a preset standard mixing ratio through the material mixing chamber and then enter the filling tank, and the air pressure in the material mixing chamber is higher than the external air pressure.

[0071] The first material and the second material can be liquid materials that need to be mixed in the fields of food, chemical industry, pharmaceuticals, daily chemical products, biotechnology, etc. Taking the food field as an example, the first material and the second material can both be related beverage liquids, such as the first material is a clear juice liquid, and the second material is a fruit liquid. After the two materials are sterilized, they are mixed according to a set standard mixing ratio to form the required fruit juice beverage.

[0072] The material mixing system based on a sterile environment in the present application is provided with two material conveying parts and a material mixing part, so that the two materials can flow to the material mixing part synchronously for mixing, and after the mixing is completed, the material can be directly filled into the filling part once to complete the operation. Compared with the traditional two-time filling, the number of material mixing and filling is saved, and the operation efficiency is improved. In addition, by providing a booster part, the generated air pressure is conveyed to the material mixing part, so that the third air pressure in the material mixing chamber is higher than the external air pressure, which can avoid or reduce the invasion of bacteria into the mixed material, so that the material is mixed in a sterile environment, and the mixing quality of the material is improved.

[0073] In one embodiment, Figure 1 and Figure 2 As shown, the stirring part of the material mixing tank 320 includes a stirring motor 325-1, a stirring shaft 325-2 and a plurality of blades 325-3. The stirring shaft 325-2 extends from the stirring inlet of the material mixing tank to the material mixing chamber 324. The blades 325-3 are arranged on the stirring shaft 325-2 and are located in the material mixing chamber 324. The materials in the containing chamber are stirred under the drive of the stirring motor 325-1. The stirring speed of the blades 325-3 can be controlled by the control component, so that the materials in the material mixing chamber 324 can be stirred at different stirring speeds according to different requirements, so that the various components of the materials in the material mixing chamber are in a fully mixed state.

[0074] Furthermore, the tank wall of the material mixing tank 320 is a hollow structure, wherein the interlayer space 328 formed by the hollow tank wall is used to accommodate hot water for heating and heat preservation of the mixed material. The interlayer space 328 is provided with an inlet and an outlet, and the inlet and the outlet are connected by a heating pipe 710, and the hot water for heating and heat preservation of the mixed material can enter the interlayer space 328 from the heating pipe 710. In addition, the upper end of the material mixing tank 320 is also provided with a flushing inlet 326, and the flushing inlet is connected to the flushing pipe 720. After the filling of the mixed material is completed, the flushing liquid can enter the material mixing chamber 324 through the flushing pipe 720 and the flushing inlet 326, and flush and clean the material mixing chamber 324. The storage tank assembly also includes a soft water injection port 327, and a soft water pipe 730 connected to the soft water injection port 327. The control component is also used to control the soft water in the soft water pipe 730 to be injected into the material mixing chamber 324 through the soft water injection port 327 when the third material capacity measured by the third capacity sensor is lower than a preset capacity threshold, thereby fully introducing the less mixed material in the material mixing chamber 324 into the filling channel 510.

[0075] In one embodiment, the steam delivery part is used to deliver steam to the first material delivery part, the second material delivery part and other related parts. The generated steam has a relatively high temperature and can be used to flush or sterilize the related parts. The steam delivery part includes a steam generating part 605, a first flushing channel 610, and a second flushing channel 620. The first flushing channel 610 and the second flushing channel 620 are connected to the steam generating part 605, the first driving pump 101 is also arranged in the first flushing channel 610, and the second driving pump 201 is also arranged in the second flushing channel 620.

[0076] like Figure 1 As shown, the first flushing channel 610 and the second flushing channel 620 are connected to the steam generating unit 605 after being connected to the steam main pipe 603. The steam main pipe 603 is provided with a steam driven pump 601 and a steam control valve 602. The steam generated by the steam generating unit 605 can flow to the steam first flushing channel 610, the steam second flushing channel 620, and the first protection channel 630 and the second protection channel 640 described below through the steam main pipe 603.

[0077] The control component is also used to detect whether the first drive pump and the second drive pump are blocked according to the data measured by the first flow sensor and the second flow sensor. When the first drive pump is detected to be blocked, the steam in the first flushing channel is controlled to flush the first drive pump. When the second drive pump is detected to be blocked, the steam in the second flushing channel is controlled to flush the second drive pump. At the same time, the control component is also used to control the first flow valve and the second flow valve to close, so as to suspend the flow of the first material and the second material to the material mixing part.

[0078] When the driving pump is flushed by high-temperature steam, the material attached to the driving pump can be softened and detached, thereby improving the flushing effect of the driving pump.

[0079] Specifically, when it is detected that the first driving pump 101 is blocked, the first flushing valve 611 arranged on the first flushing channel 610 can be controlled to open, so that steam flows from the first flushing channel 610 to the first driving pump 101 and flushes it. A corresponding first steam trap 612 is also arranged downstream of the first driving pump.

[0080] When blockage is detected in the second driving pump 201, the second flushing valve 621 arranged on the second flushing channel 620 can be controlled to open, so that steam flows from the second flushing channel 620 to the second driving pump 201 and flushes it. A corresponding second steam trap 622 is also arranged downstream of the second driving pump.

[0081] When flushing the first driving pump 101 and / or the second driving pump 201 , the corresponding first flow valve 102 and the second flow valve 202 are also controlled to be closed to suspend the flow of materials in the first storage tank 120 and the second storage tank 220 into the material mixing tank 320 .

[0082] When there is no need to flush the first drive pump 101 and / or the second drive pump 201, the first flushing valve 611 and the second flushing valve 621 are in a closed state, and the corresponding first flushing channel 610 and / or the second flushing channel 620 are in a blocked or disconnected state. At this time, steam cannot flow into the first drive pump and / or the second drive pump, and thus will not be mixed into the first material and / or the second material.

[0083] Further, when the first driving pump and / or the second driving pump is detected to be blocked, the first driving pump can be made to rotate forward or reversely, and steam can be introduced to flush it. For example, when the first driving pump is detected to be blocked, the first driving pump is controlled to reverse, and the steam in the first flushing channel is guided to flush the first driving pump during the reverse rotation.

[0084] By arranging the first driving pump and / or the second driving pump in the first flushing channel and / or the second flushing channel, during the material mixing process, the steam in the flushing channel near the driving pump provides high-temperature protection for the driving pump, preventing bacteria from invading the first material and / or the second material through the gaps in the driving pump, thereby providing further sterile protection for the materials.

[0085] Among them, the first driving pump is specifically a centrifugal pump, which has at least 4 ports (recorded as port 1, port 2, port 3 and port 4), port 1 and port 2 are respectively connected to the first material channel; port 3 and port 4 are respectively connected to the first flushing channel. During forward rotation, the channel formed by port 1 and port 2 is connected, so that the first material channel is in a conductive state, driving the first material in the first storage tank to flow in the first material channel through the conductive channel, and the channel formed by port 3 and port 4 is disconnected. On the contrary, during reverse rotation, the channel formed by port 1 and port 2 is disconnected, and the channel formed by port 3 and port 4 is connected, so that the steam in the first flushing channel can flush the centrifugal pump. The control component realizes material flow or driving pump cleaning by controlling the valve of the corresponding channel and the forward and reverse rotation of the centrifugal pump. Similarly, the second driving pump has the same structure as the first driving pump, which will not be repeated here.

[0086] In one embodiment, the steam delivery portion further includes a steam generating portion 605, a first protection channel 630, and a second protection channel 640, wherein the first protection channel and the second protection channel are in communication with the steam generating portion.

[0087] The first protection channel 630 is connected to the first material channel 110 at the first intersection through the first control valve 103. When the first control valve 103 is in a first state, the first material channel 110 is connected and the first protection channel 630 is disconnected. When the first control valve 103 is in a second state, the first material channel 110 is disconnected and the first protection channel 630 is connected.

[0088] Similarly, the second protection channel 640 is connected to the second material channel 210 at the second intersection through the second control valve 203. When the second control valve 203 is in the first state, the second material channel is connected and the second protection channel 640 is disconnected. When the second control valve 203 is in the second state, the second material channel is disconnected and the second protection channel 640 is connected. A corresponding third steam trap 631 is also provided downstream of the first protection channel 630, and a corresponding fourth steam trap 641 is also provided downstream of the second protection channel 640.

[0089] In this embodiment, the first control valve 103 is a valve used to control the material in the first storage tank to flow to the first other channel of the non-mixing channel. Similarly, the second control valve 203 is a valve used to control the material in the second storage tank to flow to the second other channel of the non-mixing channel. The first other channel may be a first reflux channel, and the second other channel may be a second reflux channel. When it is not necessary to make the material flow to the mixing channel, but it is necessary to keep the material flowing, the first control valve 103 or the second control valve 203 can be controlled to be in the second state to make the material flow from the material channel to the corresponding other valve. For example, the first material can be made to flow back to the first storage tank through the first reflux channel, and the second material can be made to flow back to the second storage tank through the second reflux channel.

[0090] When the control valve is in the first state, the corresponding material flows normally to the mixing channel, and the corresponding protection channel is in a disconnected state at the control valve position; when it is in the second state, the material is prevented from flowing to the mixing channel, and the corresponding protection channel is in a conducting state at the first control valve position, so that the steam can flow smoothly in the corresponding protection channel. Among them, since the steam will flow through the corresponding first control valve and / or second control valve when flowing in the protection channel, the first control valve and / or the second control valve are protected by high-temperature steam, avoiding the invasion of bacteria, and putting the corresponding control valve in a sterilized environment.

[0091] In one embodiment, the first control valve is a first cross valve, the second control valve is a second cross valve, the first material conveying portion further includes a first reflux channel, and the second material conveying portion further includes a second reflux channel.

[0092] The first material channel is connected through the first channel of the first cross valve, and the first protection channel is connected through the second channel of the first cross valve. The first material conveying part also includes a first reflux channel connected to one end of the first channel. When the first cross valve is in a first state, the first channel is connected and the second channel is disconnected. When the first cross valve is in a second state, the first channel is disconnected and the second channel is connected. The first material enters the first reflux channel from upstream of the first intersection of the first material channel.

[0093] like Figure 3 As shown, the first control valve includes a first port A1, a second port B1, a third port C1 and a fourth port D1. The first port A1 is connected to the upstream of the first intersection of the first material channel, the second port B1 is connected to the downstream of the first intersection of the first material channel, the third port C1 is located upstream of the first intersection of the first protection channel, and the fourth port D1 is located downstream of the first intersection of the first protection channel. The first control valve forms two channels, namely the first channel A1-B1 and the second channel C1-D1. Furthermore, the first port A1 section is also connected to the first reflux channel 130, and the valve state of the first control valve includes two states (i.e., the first state and the second state). In each state, only one of the first channel A1-B1 and the second channel C1-D1 is in the on state, and the other is in the off state.

[0094] Specifically, when in the first state, the first channel A1-B1 is connected, and the first material channel is in the connected state at the first intersection; the second channel C1-D1 is disconnected, and the first protection channel is in the disconnected state at the first intersection. When in the second state, the first channel A1-B1 is disconnected, and the first material channel is in the disconnected state at the first intersection; the second channel C1-D1 is connected, and the first protection channel is in the connected state at the first intersection.

[0095] The first port A1 is specifically a three-way valve. When the first channel A1-B1 is in a disconnected state, the three-way valve can be used to open the connection between the upstream of the first intersection of the first material channel and the first reflux channel, so that the first material flows from the upstream of the first intersection of the first material channel into the first reflux channel; when the first channel A1-B1 is in a connected state, the upstream of the first intersection of the first material channel and the first reflux channel are disconnected, and the material flows from the upstream of the first intersection of the first material channel to the downstream.

[0096] In one embodiment, the steam delivery portion further includes a first auxiliary channel 635 connected in parallel with the first protection channel 630. The first protection channel and the first auxiliary channel are in a square shape, and when the first protection channel is in a disconnected state, the first auxiliary channel is connected, and when the first protection channel is in a connected state, the first auxiliary channel is disconnected.

[0097] like Figure 3 As shown, at both ends of the first protection channel at the first intersection, the first auxiliary channel 635 is connected in parallel, and the first auxiliary valve 636 is provided in the first auxiliary channel 635. The first auxiliary channel 635 can be parallel to the second channel C1-D1, so that the first protection channel at the first intersection and the first auxiliary channel are in a square shape. When the second channel C1-D1 is in the conducting state, the control component can control the first auxiliary valve 636 to be closed; when the second channel C1-D1 is in the disconnected state, the control component controls the first auxiliary valve 636 to be turned on. In this way, when in the first state, the first protection channel is connected at both ends of the first intersection through the first auxiliary channel; when the first control valve is switched to the second state, the first protection channel is connected at both ends of the first intersection through the second channel C1-D1. Therefore, no matter what state the first control valve is in, the first protection channel is filled with steam at both ends of the first intersection, which prevents bacteria from entering the first material channel through the gap of the first control valve and contaminating the first material. Even when the second channel C1 - D1 is disconnected, since there is still steam in the first protection channel near the third port C1 and the fourth port D1 , the first material channel can always be in a sterile environment at the first intersection.

[0098] In one embodiment, the second material channel is connected through the third channel of the second cross valve, and the second protection channel is connected through the fourth channel of the second cross valve. The second material conveying part also includes a second reflux channel connected to one end of the third channel, and the other end of the third channel is connected to the first material channel and the second material channel. When the second cross valve is in a first state, the third channel is connected and the fourth channel is disconnected. When the second cross valve is in a second state, the third channel is disconnected and the fourth channel is connected. The second material enters the second reflux channel from upstream of the second intersection of the second material channel.

[0099] like Figure 4As shown, the second control valve includes a fifth port A2, a sixth port B2, a seventh port C2 and an eighth port D2, wherein the fifth port A2 is connected to the upstream of the second intersection of the second material channel, the sixth port B2 is connected to the downstream of the first intersection of the first material channel and the starting end of the mixing channel, the seventh port C2 is located upstream of the second intersection of the second protection channel, and the eighth port D2 is located downstream of the first intersection of the second protection channel. The second control valve forms two channels, namely the third channel A2-B2 and the fourth channel C2-D2. Further, the fifth port A2 is also connected to the second reflux channel 230, and the valve state of the second control valve includes two states (i.e., the first state and the second state). In each state, only one of the third channel A2-B2 and the fourth channel C2-D2 is in the on state, and the other is in the off state.

[0100] Specifically, when in the first state, the third channel A2-B2 is connected, and the second material channel is in the connected state at the second intersection; the fourth channel C2-D2 is disconnected, and the second protection channel is in the disconnected state at the second intersection. When in the second state, the third channel A2-B2 is disconnected, and the second material channel is in the disconnected state at the second intersection; the fourth channel C2-D2 is connected, and the second protection channel is in the connected state at the second intersection.

[0101] The fifth port A2 and the sixth port B2 can both be three-way valves. For the fifth port A2, when the third channel A2-B2 is in the disconnected state, the upstream of the second intersection of the second material channel can be opened by the three-way valve to be connected with the second reflux channel, so that the second material flows from the upstream of the second intersection of the second material channel to the second reflux channel; when the third channel A2-B2 is in the conducting state, the upstream of the second intersection of the second material channel is disconnected from the second reflux channel, and the material flows from the upstream of the second intersection of the second material channel to the mixing channel. For the sixth port B2, regardless of whether the third channel A2-B2 is conducting, the setting of the three-way valve allows the material to flow only from the upstream of the second intersection of the second material channel or the downstream of the first intersection of the first material channel to the mixing channel, and cannot flow between the downstream of the first intersection of the first material channel and the upstream of the second intersection of the second material channel.

[0102] In one embodiment, the steam delivery part further includes a second auxiliary channel connected in parallel with the second protection channel. The second protection channel and the second auxiliary channel are in a square shape, and when the second protection channel is in a disconnected state, the second auxiliary channel is connected, and when the second protection channel is in a connected state, the second auxiliary channel is disconnected.

[0103] like Figure 4As shown, at both ends of the second protection channel at the second intersection, a second auxiliary channel 645 is connected in parallel, and a second auxiliary valve 646 is provided in the second auxiliary channel 645. The second auxiliary channel 645 can be parallel to the fourth channel C2-D2, so that the second protection channel at the second intersection and the second auxiliary channel are in a square shape. When the fourth channel C2-D2 is in a conducting state, the control component can control the second auxiliary valve 646 to be closed; when the fourth channel C2-D2 is in a disconnected state, the control component controls the second auxiliary valve 646 to be turned on. In this way, when in the first state, the second protection channel is connected at both ends of the second intersection through the second auxiliary channel; when the second control valve is switched to the second state, the second protection channel is connected at both ends of the second intersection through the fourth channel C2-D2. Therefore, no matter what state the second control valve is in, the second protection channel is filled with steam at both ends of the second intersection, which prevents bacteria from entering the second material channel or the mixing channel through the gap of the second control valve and contaminating the second material or the mixed material. Even when the fourth channel C2 - D2 is disconnected, since there is still steam in the second protection channel near the seventh port C2 and the eighth port D2, the second material channel can always be in a sterile environment at the second intersection.

[0104] In one embodiment, the present application also provides a material mixing method in a sterile environment. This method can be applied to a material mixing system based on a sterile environment in any embodiment of the present application. Figure 5 As shown, the method includes:

[0105] Step S502, obtaining the real-time rotation speed of the first driving pump and the first flow rate set of the first material in the first material channel in a unit time.

[0106] In this embodiment, the unit time is a pre-set minimum detection cycle for detecting abnormal conditions such as blockage of the drive pump. For example, the unit time can be any suitable time such as 5 minutes, 10 minutes, etc. During the material mixing process, the duration can include multiple unit time, such as 1 hour, 2 hours, 5 hours, 24 hours, etc., or even longer periods of uninterrupted mixing. The first flow rate set reflects the flow rate of the first material in the first material channel downstream of the first drive pump at each moment in a unit time period; the real-time speed reflects the speed of the first drive pump at each moment in the unit time period.

[0107] Each sensor in the system can upload the monitored data in real time at a preset frequency, for example, it can upload data at a frequency of once per second or once every 5 seconds. Among them, the first flow sensor can upload the first flow rate of the first material in the first material channel detected in real time; the second flow sensor can upload the second flow rate of the second material in the second material channel detected in real time; the first air pressure sensor can upload the first air pressure in the first material channel detected in real time; the second air pressure sensor can upload the second air pressure in the second material channel detected in real time; the third air pressure sensor can upload the third air pressure in the material mixing chamber detected in real time; the first capacity sensor can upload the capacity data of the first material in the first storage tank in real time; the second capacity sensor can upload the capacity data of the second material in the second storage tank in real time, etc. Among them, the capacity can be any suitable value such as the above-mentioned material volume or material weight.

[0108] According to the data uploaded by each sensor and the corresponding upload time, it can be divided according to the unit time length to form a corresponding data set. Taking 5 minutes as a unit time length, the set of first flow rates received in a unit time length of 10:00:00~10:05:00 forms a corresponding first flow rate set, and the set of first air pressures received in this time period forms a corresponding first air pressure set; the set of second air pressures received forms a second air pressure set; the set of third air pressures received forms a third air pressure set; the set of first material capacity data received forms a first material capacity data set; the set of second material capacity data received forms a second material capacity data set, and so on. In addition, the control component can also obtain the speed of each drive pump in real time, such as the real-time speed of the first drive pump. Each first flow rate in the first flow rate set not only reflects the flow rate, but also reflects the corresponding data collection time.

[0109] The first flow rate may be a flow rate after data cleaning. For example, the original measured data may be subjected to data denoising, deduplication, missing value filling and other cleaning processes to form a first flow rate set.

[0110] In one embodiment, before step S502, the system may set the mixing ratio (i.e., the standard mixing ratio) of the first material and the second material to be mixed, as well as the initial opening of each valve and the initial speed of the pump in the system according to the mixing requirements of the first material and the second material to be mixed, and set the initial air pressure in the material mixing tank. When the mixing is ready, the corresponding valve is adjusted to the corresponding initial opening, and the corresponding pump is adjusted to the corresponding initial speed, so that the first material and the second material are mixed according to the required standard mixing ratio or close to the standard mixing ratio. Among them, each initial air pressure is usually the corresponding standard air pressure, the initial speed of each pump can be the corresponding standard speed, and the initial opening of each valve can be the corresponding standard opening, so that it is as close to the standard mixing ratio as possible, avoiding the need to make a large adjustment to the corresponding speed or opening during the mixing process.

[0111] During the mixing process, the opening of each valve and the speed of the pump are adaptively adjusted according to the system state, so that the material mixing ratio and material flow rate are in a dynamic balance state. For example, the speed of the first drive pump and the second drive pump can be controlled according to the PID algorithm, so that the first material and the second material are mixed at the expected flow rate.

[0112] Step S504, obtaining a standard flow rate that matches the real-time rotation speed.

[0113] In this embodiment, the system pre-sets a standard flow rate that matches the first drive pump. The standard flow rate is the reference flow rate when each drive pump in the system (including the first drive pump, the second drive pump, etc.) is in good condition without abnormal conditions such as blockage and the system is in stable operation.

[0114] In one embodiment, when the first material and the second material are mixed in a standard ratio, the standard flow rate of the first material and the standard flow rate of the second material can be selected to include multiple groups. The flow rate is related to the rotation speed of the corresponding driving pump. The system sets the standard flow rate corresponding to the driving pump at different rotation speeds according to the historical operation of the driving pump in a good state such as no blockage.

[0115] Furthermore, the speed value of the real-time speed is in a dynamically changing state, so the acquired standard flow rate is also in a corresponding changing state. Therefore, the standard flow rates corresponding to the various first flow rates in the first flow rate set are not necessarily the same. Specifically, the standard flow rates corresponding to different speed ranges can be set, and the speed range to which the real-time speed belongs at different times can be detected, and the standard flow rate corresponding to the speed range can be obtained, and the standard flow rate can be used as the standard flow rate corresponding to the first flow rate collected at the same time. This embodiment can improve the correspondence between the standard flow rate and the first flow rate, thereby improving the accuracy of the subsequent calculation of the deviation flow rate and the accuracy of the determination of blockage.

[0116] Step S506, calculating a deviation flow rate set of the first flow rate set relative to the standard flow rate.

[0117] In this embodiment, the system can calculate the deviation between each first flow rate in the first flow rate set and the standard flow rate, subtract the standard flow rate from the first flow rate, thereby obtaining the corresponding deviation flow rate, and the set of the deviation flow rates is used as the deviation flow rate set. The deviation flow rate can be a positive value or a negative value.

[0118] Step S508: determining whether the first driving pump in the first material channel is blocked based on the deviation flow rate set.

[0119] In this embodiment, the size of each deviation flow rate in the deviation flow rate set can reflect the characteristics of whether there is a blockage. The system can determine whether there is a blockage based on the characteristics reflected.

[0120] Specifically, a standard deviation range can be set, and the deviation flow rate set is calculated. The first proportion of the deviation flow rate outside the standard deviation range in the data volume of the entire deviation flow rate set is calculated. When the first proportion exceeds a preset first ratio threshold, it is determined that there is a blockage. The standard deviation range can be a deviation range corresponding to the standard flow rate. The deviation ranges corresponding to different standard flow rates are not necessarily the same. For example, the larger the standard flow rate, the larger the upper limit value of the corresponding deviation range and the smaller the lower limit value.

[0121] In one embodiment, whether a blockage occurs can be determined based on the data fluctuation of the deviation flow rate. Alternatively, whether a blockage occurs can be determined by combining the fluctuation with the first proportion or one or more other characteristics. The data fluctuation can be determined based on the speed change rate of the deviation flow rate. For example, the data whose speed change rate exceeds the corresponding speed change rate threshold can be calculated to exceed the second proportion of the overall data. When the second proportion exceeds the second proportion threshold, it is determined that a blockage exists.

[0122] Step S510, when there is a blockage, the flow of the first material and the second material to the material mixing tank is suspended, and the steam in the first flushing channel is conducted to flush the first driving pump.

[0123] In this embodiment, when there is a blockage, in addition to suspending the flow of the first material into the material mixing tank, the flow of the second material into the material mixing tank is further suspended. Specifically, one or more of the first control valve, the second control valve, the first flow valve, the second flow valve, the first drive pump, and the second drive pump can be controlled to achieve the flow of the first material and the second material into the material mixing tank.

[0124] After stopping the first material and the second material from flowing into the mixing tank, the first flushing channel can be opened, so that steam flows through the first flushing channel through the first drive pump to flush the first drive pump. Specifically, during the flushing process, the drive pump can also be controlled to reverse, thereby further improving the flushing efficiency.

[0125] In this embodiment, a blockage analysis of the first driving pump is performed at a first flow rate per unit time. By setting a standard flow rate that matches the real-time rotational speed, blockage detection of the first driving pump is performed based on the deviation flow rate between the first flow rate and the standard flow rate. When an abnormality occurs, the high-temperature steam in the first flushing channel is started to flush the driving pump. This can timely clean the first driving pump and improve the efficiency of blockage unblocking, thereby preventing the first driving pump from being blocked by the first material for a long time, causing aggravated blockage and causing more serious damage to the entire system.

[0126] In one embodiment, the method further includes: obtaining a third air pressure of the material mixing chamber measured by a third air pressure sensor in the unit time; and calculating a corresponding average air pressure based on the third air pressure. Step S504 includes: calculating an average speed in the unit time according to the real-time speed, and obtaining a standard flow rate that matches the average speed and the average air pressure.

[0127] In this embodiment, during the mixing process, the third air pressure in the material mixing chamber is higher than the external air pressure. Since the mixed material continuously enters the material mixing chamber at the material inlet of the material mixing tank, and the mixed material in the material mixing chamber also flows out through the material outlet, the mixed material therein is in a dynamic change process, so the air pressure therein is also in a changing state, and the third air pressure affects the first flow rate of the first material and the second flow rate of the second material. Under different third air pressures, the first flow rate of the first material driven by the first driving pump at the same speed may not be the same.

[0128] The third air pressure at each moment measured within a unit time period may be averaged to obtain a corresponding average air pressure.

[0129] Similarly, the system can also calculate the average speed of the real-time speed collected at each moment in the unit time period, and determine the corresponding standard flow rate based on the average speed and the average air pressure. Generally speaking, the change range of the real-time speed and the third air pressure will not be too large. In a short unit time, a standard flow rate can be determined based on the average air pressure and the average speed, so that the first flow rate set is uniformly referenced according to the standard flow rate, which can improve the efficiency of determining the standard flow rate.

[0130] In one embodiment, the above method also includes: obtaining a first material flow rate of the first material in the first storage tank under the unit time length; obtaining a second material flow rate of the second material in the second storage tank under the unit time length; and determining whether the first driving pump in the first material channel is blocked based on the deviation flow rate set, including: determining whether the first driving pump in the first material channel is blocked based on the first material flow rate, the second material flow rate and the deviation flow rate set.

[0131] The first material flow rate reflects the volume of the first material flowing out of the first storage tank per unit time; the second material flow rate reflects the volume of the second material flowing out of the second storage tank per unit time. The first material volume data collected at the start time of the unit time and the first material volume data collected at the end time can be obtained, and the first material flow rate per unit time can be calculated based on the difference between the two volume data. Similarly, the second material volume data collected at the start time of the unit time and the second material volume data collected at the end time can be obtained, and the second material flow rate per unit time can be calculated based on the difference between the two volume data.

[0132] Based on the material flow rates of the two materials per unit time, the deviation between the mixing ratio of the two materials and the standard mixing ratio can be determined, and the aforementioned deviation flow rate set can be combined to determine whether the first driving pump is blocked.

[0133] By combining the mixing ratio between the two material flows, the blockage judgment of the first driving pump can be assisted, making the blockage judgment of the first driving pump more accurate.

[0134] In one embodiment, Figure 6 As shown, determining whether the first driving pump in the first material channel is blocked based on the first material flow rate, the second material flow rate and the deviation flow rate set includes:

[0135] Step S602: Calculate the real-time mixing ratio per unit time based on the first material flow rate and the second material flow rate.

[0136] Step S604, calculating the ratio deviation between the real-time mixing ratio and the preset standard mixing ratio.

[0137] Optionally, the real-time mixing ratio = the first material flow rate / the second material flow rate. The ratio deviation can be the difference between the real-time mixing ratio and the standard mixing ratio, or the ratio between the difference and the standard mixing ratio. For example, the ratio deviation = (real-time mixing ratio - standard mixing ratio) / standard mixing ratio.

[0138] Step S606: Calculate the corresponding first quartile, second quartile and third quartile according to the deviation flow rate set.

[0139] In this embodiment, the execution order between step S602 to step S604 and step S606 is not limited, and the two can be executed in parallel or in sequence.

[0140] The first quartile (or lower quartile) Q1 represents the part with smaller deviation flow rate values ​​in the deviation flow rate concentration; the second quartile (or median) Q2 represents the midpoint of all data; the third quartile (or upper quartile) Q3 represents the part with larger values ​​in all data. The deviation flow rates in the deviation flow rate concentration can be re-sorted from small to large according to the flow rate size. For the deviation flow rates in the sorting, the deviation flow rate at the 25% position in the sorting is taken as the first quartile Q1; the deviation flow rate at the 50% position is taken as the second quartile Q2; and the deviation flow rate at the 75% position is taken as the third quartile Q3.

[0141] Step S608 , determining whether the first driving pump is blocked based on one or more parameters of the first quartile, the second quartile, the third quartile, and the proportional deviation.

[0142] It can be understood that, ideally, when the driving pump works normally, Q1<0, Q2≈0, and Q3>0. However, when the driving pump is at risk of clogging, the actually calculated Q1, Q2, and Q3 are all smaller than the expected values.

[0143] The system analyzes the values ​​of the calculated first quartile Q1, second quartile Q2, and third quartile Q3, and further verifies them in combination with the proportional deviation, thereby determining whether the first drive pump is blocked.

[0144] The system can set the corresponding first expected value Q1', the second expected value Q2' and the third expected value Q3', and calculate the first difference between the first quartile and the first expected value. , calculate the second difference between the second quartile and the second expected value , calculate the third difference between the third quartile and the third expected value .in, =Q1-Q1', =Q2-Q2', =Q3-Q3'.

[0145] when , , When the values ​​of are all smaller than the preset difference threshold, and the proportional deviation is also smaller than the preset deviation threshold, it is determined that the first driving pump is blocked. Wherein, the difference threshold and the deviation threshold can both be preset appropriate values.

[0146] In one embodiment, only the comparison The size of the proportional deviation and the difference threshold are compared. When the difference value is less than the difference threshold, it means that there is a certain deviation between the larger value part of the real-time flow rate and the larger value part of the normal flow rate, indicating that there is a risk of blockage. At this time, the deviation threshold can be combined with the deviation threshold and the to determine if there is a blockage.

[0147] In one embodiment, it is determined whether the first drive pump is blocked based on the third quartile, the speed change rate and the proportional deviation.

[0148] When a blockage occurs, especially when the blockage just occurs within the current unit time, the first material causing the blockage usually still has space to move in the first driving pump, which may cause the fluctuation of the first flow rate to be greater than normal.

[0149] Specifically, the first velocity set can be derivated to calculate the data set of the first velocity change rate corresponding to the first velocity set. The first velocity change at each moment in the first velocity change rate set is the difference between the first velocity at the corresponding moment and the first velocity at the previous moment. Recorded in T n The first flow velocity at time v n , at the previous moment (T n-1 The first flow velocity collected at time v n-1 , then the corresponding n The first velocity change rate of the first flow velocity at the time is v n -v n-1 . For the first speed change rate set formed by each calculated first speed change rate, count the number D of first speed change rates whose absolute values ​​exceed the speed change rate threshold for consecutive y first speed change rates in the set. And count the proportion of this number D in the total amount of data D0 in the entire set. Wherein, y can be any suitable value set, such as any suitable value such as 3, 4, 5, 6, etc. By counting the number D of first speed change rates whose absolute values ​​exceed the speed change rate threshold for consecutive y first speed change rates, inaccurate calculation of the first speed change rate due to abnormalities in the collected values ​​of a single first speed can be avoided.

[0150] For example, the partially continuous first speed change rates calculated under unit time are [1,2,1,3,1,-1,-3,0,-2.5,-2.8,-2.9,-3.1,0,1,2.2,2.5,2.9,3.3,1.5,2,2], and the speed change rate threshold is set to 2.1, y=3. Then, among the partially continuous first speed change rates, there are 11 with absolute values ​​greater than 2.1, but in this sequence, the absolute values ​​of the three consecutive first speed change rates exceeding the corresponding thresholds are the sequences [-2.5,-2.8,-2.9,-3.1] and [2.2,2.5,2.9,3.3], so the number D in this segment of data is 8.

[0151] For the second proportion of the number D under the calculated unit time length to the total data D0, combined with the above deviation threshold and To determine whether the first drive pump is blocked.

[0152] when When the first driving pump is less than the preset difference threshold, the proportional deviation is also less than the preset deviation threshold, and the second proportion exceeds the second proportional threshold, it is determined that there is a blockage. By combining these three parameters, the accuracy of the blockage determination for the first driving pump can be further improved.

[0153] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit it. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present application.

[0154] In addition, those skilled in the art will understand that although some embodiments herein include certain features included in other embodiments but not other features, the combination of features of different embodiments is meant to be within the scope of the present application and form different embodiments. The information disclosed in this background technology section is only intended to deepen the understanding of the overall background technology of the present application, and should not be regarded as an admission or in any form to imply that the information constitutes prior art already known to those skilled in the art.

Claims

1. A material mixing system based on a sterile environment, characterized in that: The system comprises: A first material conveying part, used for storing and conveying a first material, comprises a first material channel, a first flow valve arranged in the first material channel, a first driving pump, and a first flow sensor located downstream of the first flow valve; A second material conveying part, used for storing and conveying a second material, comprises a second material channel communicated with the first material channel, a second flow valve arranged in the second material channel, a second driving pump, and a second flow sensor located downstream of the second flow valve; A material mixing section, used for storing and mixing the first material and the second material conveyed to form a mixed material; A pressurizing part, used for delivering air pressure to the material mixing part, so that the air pressure in the material mixing chamber of the material mixing part is higher than the external air pressure; A filling part, used for filling the mixed material conveyed by the material mixing part; The steam delivery part comprises a steam generating part, a first flushing channel, a first protection channel, a first auxiliary channel connected in parallel with the first protection channel, and a second flushing channel, wherein the first flushing channel, the first protection channel and the second flushing channel are connected with the steam generating part, the first driving pump is also arranged in the first flushing channel, the second driving pump is also arranged in the second flushing channel, and the first protection channel and the first auxiliary channel are in a square shape; The first protection channel and the first material channel are connected at a first intersection through a first cross valve, the first material channel is communicated through a first channel of the first cross valve, and the first protection channel is communicated through a second channel of the first cross valve; The first material conveying portion further includes a first reflux channel connected to one end of the first channel; When the first cross valve is in a first state, the first channel is connected, and the first auxiliary channel and the second channel are disconnected; when the first cross valve is in a second state, the first channel is disconnected, and the first auxiliary channel and the second channel are connected, and the first material enters the first reflux channel from the upstream of the first intersection of the first material channel, and the first material channel is in a sterile environment at the first intersection; The control component is used to detect whether the first drive pump and the second drive pump are blocked based on the data measured by the first flow sensor and the second flow sensor. When the first drive pump is detected to be blocked, the steam in the first flushing channel is controlled to flush the first drive pump. When the second drive pump is detected to be blocked, the steam in the second flushing channel is controlled to flush the second drive pump.

2. The system according to claim 1, characterized in that The control component is also used to control the first driving pump to reverse when blockage is detected in the first driving pump, and to guide the steam in the first flushing channel to flush the first driving pump during the reversal; and to control the first flow valve and the second flow valve to close so as to suspend the flow of the first material and the second material to the material mixing section.

3. The system according to claim 1, characterized in that The first material conveying unit further includes a first storage tank for storing a first material, a first capacity sensor arranged in the first storage tank for measuring the capacity of the first material, and a first air pressure sensor arranged in the first material channel and upstream of the first driving pump; The second material conveying part further includes a second storage tank for storing a second material, a second capacity sensor arranged in the second storage tank for measuring the capacity of the second material, and a second air pressure sensor arranged in the second material channel and upstream of the second driving pump; The material mixing part includes a mixing channel and a material mixing tank, the material mixing tank includes a material inlet, a material outlet, an air pressure inlet, a material mixing chamber, and a stirring part in the material mixing chamber, the first end of the mixing channel is connected to the material inlet, and the second end is connected to the second material channel; The pressurizing unit includes a gas compressor, a gas channel, a gas pressure valve arranged on the gas channel, and a third gas pressure sensor. The gas channel connects the gas compressor and the gas pressure inlet.

4. The system according to claim 1, characterized in that The steam delivery part further includes a second protection channel, the second protection channel being in communication with the steam generation part; The second protection channel is connected to the second material channel through a second control valve at the second intersection. When the second control valve is in a first state, the second material channel is connected and the second protection channel is disconnected. When the second control valve is in a second state, the second material channel is disconnected and the second protection channel is connected.

5. The system according to claim 4, characterized in that The second control valve is a second cross valve, and the second material conveying part further includes a second reflux channel; The second material channel is connected through the third channel of the second cross valve, and the second protection channel is connected through the fourth channel of the second cross valve. The second material conveying part also includes a second reflux channel connected to one end of the third channel, and the other end of the third channel is connected to the first material channel and the second material channel. When the second cross valve is in a first state, the third channel is connected and the fourth channel is disconnected. When the second cross valve is in a second state, the third channel is disconnected and the fourth channel is connected. The second material enters the second reflux channel from upstream of the second intersection of the second material channel.

6. The system according to claim 5, characterized in that The steam delivery section further includes a second auxiliary channel connected in parallel with the second protection channel; The second protection channel and the second auxiliary channel are in a square shape. When the second protection channel is in a disconnected state, the second auxiliary channel is connected. When the second protection channel is in a connected state, the second auxiliary channel is disconnected.

7. A material mixing method based on a sterile environment, characterized in that: The method is applied to a material mixing system based on a sterile environment as claimed in any one of claims 1 to 6, and the method comprises: Acquire a real-time rotation speed of a first driving pump and a first flow rate set of a first material in a first material channel in a unit time length; Obtaining a standard flow rate that matches the real-time rotation speed; Calculating a deviation flow rate set of the first flow rate set relative to the standard flow rate; determining whether a first driving pump in the first material channel is blocked based on the deviation flow rate set; When there is a blockage, the flow of the first material and the second material to the material mixing tank is suspended, and the steam in the first flushing channel is conducted to flush the first driving pump.

8. The method according to claim 7, characterized in that The method further comprises: Acquire a third air pressure of the material mixing chamber measured by a third air pressure sensor under the unit time length; Calculating a corresponding average air pressure based on the third air pressure; The obtaining of the standard flow rate matching the real-time rotation speed comprises: calculating the average rotation speed in the unit time length according to the real-time rotation speed, and obtaining the standard flow rate matching the average rotation speed and the average air pressure.

9. The method according to claim 7 or 8, characterized in that: The method further comprises: Obtaining a first material flow rate of a first material in a first storage tank under the unit time length; Obtaining a second material flow rate of a second material in a second storage tank under the unit time length; The determining whether the first driving pump in the first material channel is blocked based on the deviation flow rate set includes: It is determined whether a first driving pump in the first material channel is blocked based on the first material flow rate, the second material flow rate, and the deviation flow rate set.

10. The method according to claim 9, characterized in that The determining whether the first driving pump in the first material channel is blocked based on the first material flow rate, the second material flow rate and the deviation flow rate set includes: Calculating the real-time mixing ratio under the unit time length based on the first material flow rate and the second material flow rate; Calculating a ratio deviation between the real-time mixing ratio and a preset standard mixing ratio; Calculate the corresponding first quartile, second quartile and third quartile according to the deviation flow rate set; It is determined whether the first driving pump is blocked based on one or more parameters among the first quartile, the second quartile, the third quartile, and the proportional deviation.

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