A drying device for producing sodium heparin

Abstract

The invention provides a drying device for sodium heparin production, comprising a shell, wherein a feed port and a discharge port are arranged on the shell, a heating component is arranged in the shell, and the heating component is used to heat the gas in the shell, a drying cylinder is horizontally arranged in the shell, and the drying cylinder is in the shape of a conical cylinder, and sieve holes with gradually increasing apertures are arranged on the cylinder wall, and sodium heparin with different particle sizes is separated from the drying cylinder through sieve holes of different sizes, so that the sodium heparin with different particle sizes is dried in the drying cylinder for different times, thereby achieving the effect of adaptively adjusting the drying time according to the particle size, and the granular sodium heparin is continuously tumbled in the drying cylinder, which also improves the uniformity of drying.

Description

Technical Field

[0001] The invention relates to the technical field of drying equipment, in particular to a drying device for producing sodium heparin. Background Art

[0002] Drying device is a device used to evaporate or remove water from wet materials or solutions, which is commonly used in industrial production processes. For pharmaceutical processes such as heparin sodium granules, drying device is one of the essential links.

[0003] For example, Chinese patent CN217929422U discloses a drying device for sodium heparin production, which dries the sodium heparin by rotating a sodium heparin placement mechanism onto a far-infrared tube axis and installing a far-infrared tube to irradiate the sodium heparin placement mechanism.

[0004] However, the above scheme ignores the fact that the sizes of heparin sodium crystals will be different during the crystallization process. Therefore, when drying heparin sodium particles, the drying time required for heparin sodium particles of different sizes is different. If all of them are placed in the heparin sodium placement mechanism and dried for the same time, the small particles of heparin sodium will be over-dried, greatly reducing the efficacy of heparin sodium, while the large particles of heparin sodium will not be fully dried, affecting the storage time. Summary of the invention

[0005] Based on this, it is necessary to provide a drying device for sodium heparin production to address the problem that the current drying device cannot adaptively adjust the drying time according to the size of sodium heparin particles.

[0006] The above purpose is achieved through the following technical solutions:

[0007] A drying device for producing sodium heparin, comprising:

[0008] A shell, wherein a feed port and a discharge port are provided on the shell, and the heparin sodium particles enter the shell through the feed port and are discharged through the discharge port;

[0009] A heating component, the heating component is located in the shell, and the heating component is used to heat the gas in the shell;

[0010] The drying cylinder is horizontally placed in the shell, the drying cylinder is a conical cylinder and a plurality of sieve holes are opened on the cylinder wall, the aperture size of the sieve holes gradually increases from the small end to the large end of the drying cylinder, the heparin sodium particles enter the drying cylinder through the feed port, the rotation of the drying cylinder drives the heparin sodium particles to move from the small end to the large end, and the movement time of the heparin sodium particles is positively correlated with the size of the heparin sodium particles.

[0011] Furthermore, an automatically opened and closed material inlet is provided on the small end of the drying cylinder, and the material inlet is configured to open when it corresponds to the material outlet and to close when it does not correspond.

[0012] Furthermore, an auger is provided in the drying cylinder, the blades of the auger are in contact with the inner wall of the drying cylinder at the bottom, and the conveying direction of the auger is opposite to the moving direction of the sodium heparin particles.

[0013] Furthermore, there are two augers, the conveying directions of the two augers are the same, the rotation speeds of the two augers are different, and the blades of the two augers have overlapping parts, the blades of the overlapping parts are made of elastic material, and the blades of the non-overlapping parts are made of hard material.

[0014] Furthermore, a driving assembly is provided on the small end of the drying cylinder, and the driving assembly is used to drive the drying cylinder and two augers to rotate.

[0015] Furthermore, the driving assembly includes a rotating disk and a first driving motor, the rotating disk is arranged in the shell, the small end of the drying cylinder is rotatably arranged on the rotating disk and a gear ring is nested on the inner wall of the small end, the first driving motor is fixedly arranged on the rotating disk, the rotating gear of the first driving motor is meshed with the gear ring, and the rotation of the first driving motor drives the drying cylinder to rotate.

[0016] Furthermore, a first transmission gear and a second transmission gear that mesh with each other are rotatably arranged on the rotating disk, the rotating gear of the first drive motor meshes with the first transmission gear, the first transmission gear and the second transmission gear have different radii, and the first transmission gear and the second transmission gear respectively drive two augers to rotate.

[0017] Furthermore, the rotating shafts of the first transmission gear and the second transmission gear are universally connected to the rotating shafts of the two augers.

[0018] Furthermore, there are multiple drying cylinders, a rotating shaft is horizontally placed in the middle of the shell, and multiple drying cylinders are evenly distributed on the outer circumference of the rotating shaft. The rotating shaft drives the multiple drying cylinders to revolve around the axis of the rotating shaft.

[0019] Furthermore, the rotating shaft is provided with connecting rods radially distributed along the rotating shaft, the connecting rods are rotatably connected to the rotating disk, and the connecting rods are provided with a second drive motor. The second drive motor is configured to maintain the position of the auger on the rotating disk at the inner wall below the drying cylinder when the rotating shaft drives the drying cylinder to revolve.

[0020] The beneficial effects of the present invention are:

[0021] The present invention uses a horizontally placed drying cylinder in the shape of a tapered cylinder, and sieve holes with gradually increasing apertures are provided on the cylinder wall. Heparin sodium particles of different sizes are separated from the drying cylinder through the sieve holes of different sizes, so that heparin sodium particles of different sizes are dried in the drying cylinder for different times, thereby achieving the effect of adaptively adjusting the drying time according to the particle size, and the granular heparin sodium continuously rolls in the drying cylinder, which also improves the uniformity of drying.

[0022] The present invention arranges an auger in the drying cylinder whose conveying direction is opposite to the moving direction of the granular heparin sodium in the drying cylinder, and the blades of the auger are in contact with the inner wall of the drying cylinder at the bottom. On the one hand, the flow speed of the granular heparin sodium in the drying cylinder can be slowed down to improve the drying quality. On the other hand, the inner wall of the drying cylinder can be scraped to avoid clogging of the sieve holes. At the same time, the rolling effect of the granular heparin sodium is improved, and the uniformity of drying is further improved.

[0023] The present invention arranges two augers in a drying cylinder. The two augers rotate in opposite directions and have a speed difference. The blades of the two augers also have overlapping parts. The blades of the overlapping parts are twisted together, which can beat the granular heparin sodium passing through the augers in the drying cylinder, so that the granular heparin sodium is dispersed and avoids mutual adhesion.

[0024] The present invention provides a plurality of drying cylinders, and the plurality of drying cylinders revolve and rotate at the same time, so that materials can be continuously received, thereby improving the drying efficiency and the drying quality. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 A schematic diagram of the structure of a drying device for producing sodium heparin provided in one embodiment of the present invention.

[0026] Figure 2 for Figure 1 A left view of a drying device for producing sodium heparin provided in one embodiment.

[0027] Figure 3 for Figure 2 A cross-sectional view along AA of a drying device for producing sodium heparin provided in one embodiment.

[0028] Figure 4 for Figure 1 A front view of a drying device for producing sodium heparin provided in one embodiment.

[0029] Figure 5 for Figure 4 A cross-sectional view along BB of a drying device for producing sodium heparin provided in an embodiment.

[0030] Figure 6 A schematic diagram of the structure of multiple drying cylinders inside a drying device for producing sodium heparin provided in one embodiment of the present invention.

[0031] Figure 7 for Figure 6 A front view of a single drying cylinder of a drying device for producing sodium heparin provided in one embodiment.

[0032] Figure 8 for Figure 7 A cross-sectional view along CC of a single drying cylinder of a drying device for producing sodium heparin provided in one embodiment.

[0033] Fig. 9 for Figure 7 A cross-sectional view along DD of a single drying cylinder of a drying device for producing sodium heparin provided in one embodiment.

[0034] Fig.10 for Figure 6 A left view of a single drying cylinder of a drying device for producing sodium heparin provided in one embodiment.

[0035] Fig.11 for Fig.10 A cross-sectional view along EE of a single drying cylinder of a drying device for producing sodium heparin provided in one embodiment.

[0036] Fig.12 A schematic diagram of the structure of a rotating disk of a drying device for producing sodium heparin provided in one embodiment of the present invention.

[0037] in:

[0038] 100, housing; 110, supporting legs; 120, feed port; 130, discharge port; 140, guide plate; 150, heating assembly;

[0039] 200, drying cylinder; 210, feeding port; 220, sieve hole; 230, auger; 240, rotating shaft; 250, connecting rod; 260, connecting frame;

[0040] 300, rotating plate; 310, gear slot; 320, connecting hole; 330, first transmission gear; 340, second transmission gear; 350, universal joint; 360, gear ring;

[0041] 400, a first driving motor; 410, a rotating gear; 420, a second driving motor; 430, a third driving motor. DETAILED DESCRIPTION

[0042] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below through embodiments and in conjunction with the accompanying drawings. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0043] The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the objects described and do not have any order or technical meaning. The "connection" and "coupling" mentioned in this application, unless otherwise specified, include direct and indirect connections (couplings). In the description of the present invention, it should be understood that the orientation or position relationship indicated by the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", etc. are based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present invention.

[0044] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0045] Refer to the following Figure 1-Figure 12 To describe a drying device for producing sodium heparin in the present application.

[0046] A drying device for sodium heparin production is suitable for drying granular materials, especially for drying granular sodium heparin, comprising a shell 100, on which a feed port 120 and a discharge port 130 are provided. The feed port 120 is used for feeding granular sodium heparin. When drying is completed, the granular sodium heparin is discharged from the discharge port 130, thereby completing drying. A heating component 150 is provided in the shell 100, and the heating component 150 is used to heat the gas in the shell 100 so as to dry the granular sodium heparin. A drying cylinder 200 is also horizontally arranged in the shell 100, that is, the axis of the drying cylinder 200 is horizontal. The drying cylinder 200 is in the shape of a conical cylinder and a plurality of sieve holes 220 are provided on the cylinder wall. The aperture of the sieve holes 220 gradually increases from the small end to the large end of the drying cylinder 200. After the granular sodium heparin enters the shell 100 from the feed port 120, it enters the shell 100. The granular heparin sodium enters the drying cylinder 200. Since the drying cylinder 200 is in the shape of a tapered cylinder, the side wall of the drying cylinder 200 is inclined from the small end to the large end, and the granular heparin sodium enters the drying cylinder 200 from the small end. When the drying cylinder 200 rotates, the granular heparin sodium moves from the small end to the large end of the drying cylinder 200 under the action of gravity. During the movement, the drying cylinder 200 rotates so that the granular heparin sodium rolls while moving, so that the granular heparin sodium can be evenly heated and dried more evenly.

[0047] The time that the granular sodium heparin particles move in the drying cylinder 200 is positively correlated with the size of the sodium heparin particles. It can be understood that, since the sieve holes 220 are provided on the side wall, the sodium heparin with smaller particle size will leave the drying cylinder 200 and fall directly to the discharge port 130 after passing through the sieve holes 220 with smaller apertures, and the time for moving in the drying cylinder 200 is shorter, that is, the drying time is shorter, thereby avoiding excessive drying of the sodium heparin with smaller particle size; and the sodium heparin with larger particle size will leave the drying cylinder 200 only after passing through the sieve holes 220 with appropriate aperture sizes, and the aperture size of the sieve holes 220 on the drying cylinder 200 of the present application gradually increases from the small end to the large end of the drying cylinder 200, so the sodium heparin with larger particle size moves longer in the drying cylinder 200, that is, the drying time is longer, thereby ensuring that the sodium heparin with larger particle size can be fully dried.

[0048] By providing a conical drying cylinder 200 and opening sieve holes 220 with gradually increasing apertures on the cylinder wall, heparin sodium of different particle sizes takes different drying times in the drying cylinder 200, thereby achieving the effect of adaptively adjusting the drying time according to the particle size, and the granular heparin sodium continuously tumbles in the drying cylinder 200, which also improves the uniformity of drying.

[0049] It should be noted that the heating component 150 can be a heater, a dryer, an infrared tube, etc., which can be any device that can evenly heat the gas in the shell 100, and is not specifically limited here.

[0050] In a further embodiment, an automatically opened and closed feed port 210 is provided on the small end of the drying cylinder 200, and the feed port 210 is configured to open when the feed port 210 corresponds to the feed port 120, and to close when it does not correspond, so as to prevent the granular heparin sodium in the drying cylinder 200 from being thrown out when the drying cylinder 200 rotates. In addition, no sieve hole 220 is provided at the feed port 210, so as to prevent the granular heparin sodium with a smaller particle size from directly escaping from the sieve hole 220 when the granular heparin sodium enters the drying cylinder 200, so as to cause the heparin sodium with a smaller particle size to directly enter the discharge port 130 without being dried.

[0051] It should be noted that the rotation speed of the drying cylinder 200 is relatively slow. It is assumed that all the granular sodium heparin in the drying cylinder 200 will be separated from the sieve holes 220 when the drying cylinder 200 rotates one circle. When the feed port 210 on the drying cylinder 200 rotates again to correspond to the feed port 120, the granular sodium heparin continues to enter the drying cylinder 200, thereby realizing continuous operation of the device and greatly improving the drying efficiency.

[0052] It should also be noted that the automatically opened and closed feed port 210 in this embodiment can be an electromagnetic valve, which automatically opens when the electromagnetic valve senses a position corresponding to the feed port 120, and automatically closes when the feed port 120 is not sensed. Of course, it can also be other structures that can achieve the above functions, which are not specifically limited here.

[0053] In a further embodiment, an auger 230 is provided in the drying cylinder 200, and the blades of the auger 230 are in contact with the inner wall of the drying cylinder 200 at the bottom. The size of the auger 230 is about one-third of the size of the drying cylinder 200, and the blades of the auger 230 are partially in contact with the inner wall of the drying cylinder 200 at the bottom, but not all. The spiral degree of the blades of the auger 230 is low and the conveying direction of the auger 230 is opposite to the moving direction of the granular sodium heparin, so that the blades of the auger 230 can slow down the moving speed of the granular sodium heparin in the drying cylinder 200 when rotating, and make the rolling effect of the granular sodium heparin better. It can be understood that adjusting the rotation speed of the blades of the auger 230 can adjust the degree of slowing down the moving speed and rolling effect of the granular material in the drying cylinder 200, thereby further improving the drying uniformity of the granular sodium heparin.

[0054] At the same time, the auger 230 provided in the drying cylinder 200 can also scrape the inner wall of the drying cylinder 200 to prevent the granular heparin sodium from adhering to the inner wall of the drying cylinder 200 and blocking the sieve hole 220 .

[0055] In a further embodiment, there are two augers 230 in the drying cylinder 200, and the blades of the two augers 230 are in contact with the inner wall of the drying cylinder 200 at the bottom. The conveying directions of the two augers 230 are the same but the rotation speeds are different, and the blades of the two augers 230 have overlapping parts, and the blade material of the overlapping part is elastic material, and the material of the non-overlapping part is hard material. When the two augers 230 rotate, due to the overlapping part, the overlapping parts of the blades of the two augers 230 will twist together and beat against each other, and the non-overlapping part is made of hard material, which can provide support for the blades and prevent the blades from twisting excessively.

[0056] It should be noted that the elastic material mentioned above can be wear-resistant rubber or elastic plastic, etc., while the hard material can be metal or hard plastic, which is not specifically limited here.

[0057] The above arrangement can make the granular sodium heparin in the drying cylinder 200 be beaten. Specifically, when the two augers 230 rotate, when the granular sodium heparin falls on the blade of the other augers 230 after being beaten by the blade of one of the augers 230, due to the speed difference, the speed of the granular sodium heparin changes, so that the granular sodium heparin is dispersed, thereby preventing the sodium heparin with smaller particle size from adhering to the sodium heparin with larger particle size, resulting in the small-sized sodium heparin particles not passing through the sieve holes 220 of the corresponding aperture, but being dried together with the larger-sized sodium heparin and over-dried. After the granular sodium heparin is dispersed, the above phenomenon can be effectively avoided.

[0058] It should be noted that there are many ways to achieve the same conveying direction of the two augers 230. For example, the blades of the two augers 230 may have the same rotation direction and the same rotation direction, or the blades of the two augers 230 may have opposite rotation directions and opposite rotation directions. The latter is adopted in the embodiment of the present application, that is, the blades of the two augers 230 have opposite rotation directions and opposite rotation directions. The advantage of using two augers 230 with opposite rotation directions is that when the blades of one of the augers 230 hit and roll onto the blades of the other augers 230, the reverse rotation of the blades of the other augers 230 can change the direction of the granular heparin sodium being hit, thereby further improving the dispersion of the granular heparin sodium.

[0059] Specifically, a driving assembly is provided on the small end of the drying cylinder 200, and the driving assembly is used to drive the drying cylinder 200 and the two augers 230 to rotate. The driving assembly includes a first driving motor 400 and a rotating disk 300. The rotating disk 300 is located in the shell 100, and the small end of the drying cylinder 200 is rotatably set on the rotating disk 300, and a ring gear 360 is nested on the inner wall of the small end. The first driving motor 400 is fixedly set on the rotating disk 300, and the rotating gear 410 of the first driving motor 400 is engaged with the ring gear 360. When the first driving motor 400 rotates, it drives the ring gear 360 to rotate. The ring gear 360 is fixedly set on the drying cylinder 200, so the ring gear 360 drives the drying cylinder 200 to rotate.

[0060] Specifically, the rotating disk 300 is also rotatably provided with two mutually meshing first transmission gears 330 and second transmission gears 340, and the rotating gear 410 of the first drive motor 400 is meshed with the first transmission gear 330. The first drive motor 400 rotates to drive the drying cylinder 200 to rotate while driving the first transmission gear 330 to rotate. The first transmission gear 330 drives the second transmission gear 340 to rotate, and the radii of the first transmission gear 330 and the second transmission gear 340 are different, so the rotation speeds of the first transmission gear 330 and the second transmission gear 340 are different, and the rotation directions are opposite. The first transmission gear 330 and the second transmission gear 340 respectively drive the two augers 230 to rotate, thereby achieving opposite rotation directions and different rotation speeds of the two augers 230.

[0061] like Figure 8 and Fig. 9 As shown, for ease of connection, the rotating shafts of the first transmission gear 330 and the second transmission gear 340 are universally connected to the two augers 230. Since the rotating shafts of the two augers 230 are not horizontal but slightly inclined, a universal joint 350 is specifically used to connect the two, so that the first transmission gear 330 and the second transmission gear 340 can drive the two augers 230 to rotate.

[0062] like Fig.11 and Fig.12 As shown, in order to facilitate the installation of the first transmission gear 330 and the second transmission gear 340, a gear groove 310 is provided on the rotating disk 300, and the first transmission gear 330 and the second transmission gear 340 are both located in the gear groove 310, and the rotating gear 410 of the first drive motor 400 is also located in the gear groove 310, and the ring gear 360 at the small end of the drying cylinder 200 is also located at the periphery of the gear groove 310, so that the rotating gear 410 of the first drive motor 400 is meshed with the ring gear 360 and the first transmission gear 330 at the same time.

[0063] In a further embodiment, Figure 3As shown, a plurality of drying cylinders 200 are arranged in the housing 100. The embodiment of the present application takes four drying cylinders as an example. A rotating shaft 240 is horizontally arranged in the middle of the housing 100. The rotating shaft 240 connects the four drying cylinders 200, and the four drying cylinders 200 are evenly distributed on the outer periphery of the rotating shaft 240. When the rotating shaft 240 rotates, the four drying cylinders 200 are driven to revolve. At the same time, the four drying cylinders 200 also rotate. The four drying cylinders 200 pass under the feed port 120 of the housing 100 in sequence. Whenever the feed port 210 of the drying cylinder 200 corresponds to the feed port 120, the feed port 210 is opened to allow the granular heparin sodium to enter the drying cylinder 200. A guide plate 140 is arranged in the housing 100. A tiny through hole is opened on the guide plate 140 to facilitate the passage of the heated gas, so as to avoid the guide plate 140 hindering the drying of the granular heparin sodium by the heated gas. The granular heparin sodium separated from the drying cylinder 200 falls into the discharge port 130 through the guide plate 140. Four drying drums 200 are arranged to rotate and receive materials in sequence, and the four drying drums 200 work independently, thereby improving the drying efficiency of the granular heparin sodium and achieving better drying quality.

[0064] Specifically, a connecting rod 250 is provided on the rotating shaft 240 and is radially distributed along the rotating shaft 240. The connecting rod 250 is rotatably connected to the rotating disk 300 at the small end of the drying cylinder 200. A second drive motor 420 is provided on the rotating rod. The second drive motor 420 can drive the rotating disk 300 to rotate. Since the two augers 230 are connected to the first transmission gear 330 and the second transmission gear 340 on the rotating disk 300, in order to ensure that the positions of the two augers 230 do not change relative to the position of the drying cylinder 200, when the rotating shaft 240 drives the drying cylinder 200 to revolve, the second drive motor 420 drives the rotating disk 300 to rotate so that the augers 230 are always located on the inner wall of the drying cylinder 200 at the bottom.

[0065] It is understandable that, due to the revolution arrangement of the plurality of drying cylinders 200, in order to ensure that the position of the auger 230 is always located on the inner wall of the drying cylinder 200, the rotating disk 300 needs to be rotatably connected to the connecting rod 250. If the rotating disk 300 is fixedly connected to the connecting rod 250, when the drying cylinder 200 is revolving, the auger 230 is located on the inner wall of the drying cylinder 200 only when the drying cylinder 200 is located directly above the rotating shaft 240. Therefore, the rotating disk 300 is driven to rotate by the second driving motor 420 to maintain the relative position of the auger 230 and the drying cylinder 200 unchanged, that is, no matter where the drying cylinder 200 revolves, the auger 230 in the drying cylinder 200 is always located on the inner wall of the drying cylinder 200 at that position, and the granular heparin sodium is also always located at the inner wall of the drying cylinder 200 at the bottom under the action of gravity, so that the auger 230 always has a slapping effect on the granular heparin sodium.

[0066] like Figure 6 , Figure 7 and Fig.12 As shown, in order to facilitate the rotational connection between the connecting rod 250 and the rotating disk 300, two connecting holes 320 are provided on the rotating disk 300, and the two connecting holes 320 are located in the same horizontal plane. A connecting frame 260 is fixedly connected to the two connecting holes 320, and the other end of the connecting frame 260 is connected to the second driving motor 420.

[0067] Specifically, in this embodiment, a third driving motor 430 is further provided. The third driving motor 430 is fixedly disposed on the housing 100 , and the third driving motor 430 drives the rotation of the rotating shaft 240 .

[0068] Specifically, in order to facilitate material discharge, a support leg 110 is provided at the bottom of the shell 100 , and the support leg 110 supports the shell 100 at a certain height, so that a collection box (not shown in the figure) is placed at the bottom of the discharge port 130 .

[0069] The specific working process of a drying device for producing sodium heparin provided by the present application is described in combination with the above embodiments:

[0070] start up:

[0071] The heating assembly 150 is started to heat the gas in the housing 100. After the gas is heated, the first drive motor 400, the second drive motor 420 and the third drive motor 430 are started. The third drive motor 430 drives the rotating shaft 240 to rotate. The rotation of the rotating shaft 240 drives the four drying cylinders 200 to revolve. The second drive motor 420 drives the rotating disk 300 to rotate, so that the positions of the two augers 230 connected to the first transmission gear 330 and the second transmission gear 340 on the rotating disk 300 remain relatively unchanged with the position of the drying cylinder 200, that is, the two augers 230 are kept relatively unchanged. The position 30 is always located at the inner wall below the drying cylinder 200. The first drive motor 400 drives the drying cylinder 200 to rotate, and at the same time drives the first transmission gear 330 and the second transmission gear 340 to rotate. Since the first transmission gear 330 and the second transmission gear 340 are meshed with each other and have different radii, the two augers 230 are driven to rotate in opposite directions and at different speeds. The blades of the two augers 230 rotate in opposite directions, which makes the conveying directions of the two augers 230 the same, and the conveying directions of the two augers 230 are from the large end to the small end of the drying cylinder 200.

[0072] Add ingredients:

[0073] The granular sodium heparin to be dried is discharged into the housing 100 from the feed port 120 , and the feed port 210 of the drying cylinder 200 is opened when it corresponds to the feed port 120 , and the granular sodium heparin enters the drying cylinder 200 through the feed port 210 .

[0074] drying:

[0075] Since the drying cylinder 200 is in the shape of a cone cylinder and enters the drying cylinder 200 from the small end, as the drying cylinder 200 rotates, the granular heparin sodium moves from the small end to the large end of the drying cylinder 200 under the action of gravity. At the same time, the conveying direction of the two augers 230 is opposite to the moving direction of the granular heparin sodium, and the two augers 230 do not completely cover the inner wall of the lower end of the drying cylinder 200, but are partially in contact, so as to slow down the moving speed of the granular heparin sodium and improve the rolling effect of the granular heparin sodium in the drying cylinder 200. The blades of the two augers 230 have overlapping parts, and the blades at the overlapping parts are made of elastic material, so that the overlapping parts of the two augers 230 blades are twisted with each other, so that the granular heparin sodium passing through the blades of the augers 230 is beaten and then rolls back and forth on the two augers 230 blades. By setting the opposite rotation direction and speed difference, the granular heparin sodium is dispersed to prevent the granular heparin sodium from sticking to each other. Meanwhile, a plurality of sieve holes 220 are provided on the drying cylinder 200, and the aperture of the sieve holes 220 gradually increases from the small end to the large end of the drying cylinder 200. After moving to the sieve holes 220 of suitable aperture, the heparin sodium of different particle sizes will leave the drying cylinder 200 and be guided to the discharge port 130 through the guide plate 140. For example, the heparin sodium with a smaller particle size will leave the drying cylinder 200 from the small sieve holes 220 after moving a shorter distance, and the drying time is short, thereby avoiding over-drying; while the heparin sodium with a larger particle size will leave the drying cylinder 200 from the large sieve holes 220 after moving a longer distance, and the drying time is longer, thereby avoiding insufficient drying.

[0076] Nesting:

[0077] The dried granular heparin sodium leaves the drying cylinder 200 and is guided to the discharge port 130 through the guide plate 140 to complete the discharge.

[0078] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0079] The above-described embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the present invention. It should be pointed out that, for a person of ordinary skill in the art, several modifications and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the attached claims.

Claims

1. A drying device for producing heparin sodium, characterized in that: include: A shell, wherein a feed port and a discharge port are provided on the shell, and the heparin sodium particles enter the shell through the feed port and are discharged through the discharge port; A heating component, the heating component is located in the shell, and the heating component is used to heat the gas in the shell; A drying cylinder, wherein the drying cylinder is horizontally placed in the shell, the drying cylinder is a conical cylinder and has a plurality of sieve holes on the cylinder wall, the aperture of the sieve holes gradually increases from the small end to the large end of the drying cylinder, the heparin sodium particles enter the drying cylinder through the feed port, the rotation of the drying cylinder drives the heparin sodium particles to move from the small end to the large end, and the movement time of the heparin sodium particles is positively correlated with the size of the heparin sodium particles; An auger is provided in the drying cylinder, the blades of the auger are in contact with the inner wall of the drying cylinder at the bottom, and the conveying direction of the auger is opposite to the moving direction of the heparin sodium particles; There are two augers, the conveying directions of the two augers are the same, the rotation speeds of the two augers are different, and the blades of the two augers have overlapping parts, the blades of the overlapping parts are made of elastic material, and the blades of the non-overlapping parts are made of hard material; A driving assembly is provided on the small end of the drying cylinder, and the driving assembly is used to drive the drying cylinder and the two augers to rotate; The driving assembly includes a rotating disk and a first driving motor, the rotating disk is arranged in the housing, the small end of the drying cylinder is rotatably arranged on the rotating disk, and a gear ring is nested on the inner wall of the small end, the first driving motor is fixedly arranged on the rotating disk, the rotating gear of the first driving motor is meshed with the gear ring, and the rotation of the first driving motor drives the drying cylinder to rotate; The rotating disk is rotatably provided with a first transmission gear and a second transmission gear meshing with each other, the rotating gear of the first driving motor meshes with the first transmission gear, the first transmission gear and the second transmission gear have different radii, and the first transmission gear and the second transmission gear respectively drive two augers to rotate; There are multiple drying cylinders, a rotating shaft is horizontally placed in the middle of the shell, and the multiple drying cylinders are evenly distributed on the outer circumference of the rotating shaft. The rotating shaft drives the multiple drying cylinders to revolve around the axis of the rotating shaft.

2. The drying device for producing heparin sodium according to claim 1, characterized in that: An automatically opened and closed material inlet is provided on the small end of the drying cylinder, and the material inlet is configured to open when it corresponds to the material outlet and to close when it does not correspond.

3. The drying device for producing heparin sodium according to claim 1, characterized in that: The rotating shafts of the first transmission gear and the second transmission gear are universally connected to the rotating shafts of the two augers.

4. The drying device for producing heparin sodium according to claim 1, characterized in that: The rotating shaft is provided with connecting rods distributed radially along the rotating shaft, the connecting rods are rotatably connected to the rotating disk, the connecting rods are provided with a second driving motor, and the second driving motor is configured to maintain the position of the auger on the rotating disk always at the inner wall below the drying cylinder when the rotating shaft drives the drying cylinder to revolve.

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