Metabolite detection kit in exhaled breath condensate for lung disease detection

Abstract

The application discloses a metabolite detection kit in exhaled breath condensate for lung disease detection and belongs to the technical field of detection kits. The kit is placed in the position of an external detection mechanism, multiple test tubes correspond to multiple detection stations under the detection mechanism, a micro motor works to drive the driving disc to rotate, the driving disc drives the shifting rod to rotate, the shifting rod can rotate outside the convex outer wall of the rotating disc, cavities are formed between adjacent two convexes, the shifting rod can push the rotating disc to rotate through the cavities in the rotating process, the rotating disc can rotate around the center of the bearing seat, the rotating disc drives multiple test tubes to rotate synchronously through the erecting assembly, and therefore the test tubes can be pushed to the next detection station after completing the current detection process, the shifting rod continuously rotates, the shifting rod can push the rotating disc to rotate intermittently, the positions of the multiple test tubes are synchronously adjusted, and the purpose of continuously and efficiently and stably detecting the test tubes in the kit is effectively achieved.

Description

TECHNICAL FIELD

[0001] The application belongs to the technical field of detection kits, and specifically relates to a metabolic substance detection kit in exhaled breath condensate for lung disease detection. BACKGROUND

[0002] Exhaled breath condensate is a source of non-invasive biomarkers and contains water and dissolved gas metabolites from the lower respiratory tract, which can reflect the physiological state and pathological changes of individuals, and thus has potential application value in disease diagnosis and monitoring. Metabolites in exhaled breath condensate are related to the occurrence and development of various diseases.

[0003] At present, in lung disease detection, the metabolites in exhaled breath condensate are placed in test tubes, and then the test tubes containing the metabolites are placed in a detection kit for detection. Since the clamping holes for supporting and limiting the test tubes in the detection kit are usually designed in one piece, the size of the clamping holes cannot be changed, and thus it is difficult to adapt to the limiting work of test tubes of different specifications. In the detection process of the test tubes containing the metabolites in the detection kit, the detection process is mostly divided into multiple detection procedures. After completing a single detection procedure, the detection kit needs to be removed and then transferred to other detection areas. During the transfer process, the current detection structure is in a non-working state, which delays the working time and makes it difficult to achieve the purpose of continuously and efficiently and stably detecting the detection kit. SUMMARY

[0004] In order to overcome the above defects, the application provides a metabolic substance detection kit in exhaled breath condensate for lung disease detection, which solves the problems that the clamping holes for supporting and limiting the test tubes in the detection kit are usually designed in one piece, the size of the clamping holes cannot be changed, and thus it is difficult to adapt to the limiting work of test tubes of different specifications, and the detection process of the test tubes containing the metabolites in the detection kit is mostly divided into multiple detection procedures, and it is difficult to achieve the purpose of continuously and efficiently and stably detecting the detection kit.

[0005] To achieve the above purpose, the application provides the following technical scheme: a metabolic substance detection kit in exhaled breath condensate for lung disease detection, comprising a box body, a supporting base is arranged at the bottom of the box body, a box cover is arranged at the top of the box body, a blocking ring is overlapped at the bottom of the box cover, the blocking ring is clamped on the outer wall of the box body, a mounting assembly is arranged in the box body, a plurality of test tubes are mounted on the mounting assembly, a material supporting assembly is fixedly connected to the bottom end of the mounting assembly, the bottom ends of the plurality of test tubes are clamped in the material supporting assembly, and a plurality of extrusion assemblies are equidistantly arranged on the material supporting assembly.

[0006] The top of the extrusion assembly is connected to two limiting components, which are installed inside the support assembly. The two opposing limiting components are provided with positioning components, which are connected to the support assembly. The bottom of the material support assembly is connected to a partition, which is installed at the bottom of the box. Below the partition is a guide assembly, which is installed inside the support base. The top of the guide assembly penetrates the bottom of the box and is connected to the outside of the material support assembly.

[0007] As a further aspect of the present invention: the mounting component includes a chuck, the chuck is disposed inside the box, and the chuck has placement holes respectively corresponding to the positions of several test tubes, the test tubes pass through the placement holes, and three fixing posts are fixedly connected to the bottom of the chuck, the bottom ends of the three fixing posts are fixed to the material support component.

[0008] As a further embodiment of the present invention: the material support assembly includes a rotating disk, the top of the rotating disk is fixedly connected to the bottom of the support assembly, a plurality of protrusions on the outer wall of the rotating disk are respectively provided with limiting grooves, the bottom of the test tube is engaged in the limiting grooves, and the protrusions on the outer wall of the rotating disk are connected to the guide assembly.

[0009] As a further embodiment of the present invention: a locking hole is provided in the middle of the rotating disk, a bearing seat is installed in the locking hole, the bearing seat is disposed on the partition plate, and the rotating disk is installed at the bottom of the inner wall of the box.

[0010] As a further aspect of the present invention: the extrusion assembly includes an air cushion seat, the air cushion seat is installed at the bottom of the inner wall of the limiting groove, the air cushion seat is provided with a pressure rod, the top end of the pressure rod contacts the bottom end of the test tube, and air guide tubes are respectively connected to both sides of the air cushion seat, the end of the air guide tube away from the air cushion seat is connected to one end of the limiting assembly.

[0011] As a further aspect of the present invention: the limiting component includes a clamping plate, the clamping plate being a soft rubber plate with an arc-shaped design, the inner wall of the clamping plate being fitted against the outer wall of the test tube, a sliding column being fixedly connected to the outer wall of the clamping plate, a piston cylinder being sleeved on the sliding column, the piston cylinder being engaged with the inner wall of the placement hole, a first spring being sleeved on the sliding column, one end of the first spring being fixedly connected to the outer wall of the clamping plate, and the other end of the first spring being fixedly connected to the inner wall of the placement hole.

[0012] As a further embodiment of the present invention: the top of the sliding column is provided with a plurality of slots, one of which is engaged with the bottom end of the positioning component, the bottom of the sliding column is fixedly connected to a limiting block, the bottom of the inner wall of the piston cylinder is provided with a slide channel, and the limiting block is slidably connected in the slide channel.

[0013] As a further scheme of the present application: the positioning assembly comprises a dial ring, two sides of the bottom of the dial ring are fixedly connected with clamping strips respectively, the clamping strips are designed in L shape, and bottom ends of the clamping strips are embedded in the erecting assembly and clamped in clamping grooves, the position of the bottom end of the clamping strip away from the clamping plate is designed as an arc surface, and a second spring is fixedly installed between the clamping strip and the erecting assembly.

[0014] As a further scheme of the present application: the guiding assembly comprises a micro motor, the micro motor is installed in a supporting base, an output shaft of the micro motor penetrates through a partition plate and a box body and is connected with a driving disc, a dial rod is arranged at the edge of the top of the driving disc, and the dial rod is in contact with protrusions of the outer wall of the rotating disc.

[0015] Compared with the prior art, the present application has the beneficial effects that:

[0016] 1、In the present application, the test tube containing metabolites is placed on the erecting assembly in the box body, the test tube penetrates through the erecting assembly and is in contact with the material supporting assembly, when the test tube extrudes the extruding assembly on the material supporting assembly, the extruding assembly extrudes the test tube through the limiting assembly, so that the test tube can be stably arranged in the erecting assembly in the box body, during the detection of the test tube in the box body, the box body is placed at the position of the external detection mechanism, so that a plurality of test tubes correspond to a plurality of detection stations under the detection mechanism, the micro motor is controlled to work to drive the driving disc to rotate, the driving disc drives the dial rod to rotate, so that the dial rod can rotate outside the protrusions of the outer wall of the rotating disc, cavities are formed between adjacent two protrusions, so that the dial rod can drive the rotating disc to rotate through the cavities during rotation, the rotating disc can rotate around the center of the bearing seat, and the rotating disc drives a plurality of test tubes to rotate synchronously through the erecting assembly, so that the test tube can be pushed to the next detection station after completing the current detection process, and the dial rod can intermittently drive the rotating disc to rotate, so as to synchronously adjust the positions of the plurality of test tubes, thereby effectively realizing the purpose of continuously and efficiently and stably detecting the test tube in the box body.

[0017] 2、The present application, by inserting the test tube into the hole and making its bottom end contact with the pressure bar, the pressure bar can extrude the air cushion seat after being pressed, the air cushion seat can guide the gas into the piston cylinder through two air guide pipes after deformation, and the piston cylinder can push the slide column to move with the increase of the air pressure in the piston cylinder, so that the two slide columns drive two clamping plates to clamp the outer wall of the test tube respectively, the rubber soft plate prevents the clamping plate from being in hard contact with the test tube to cause damage to the test tube, and the rubber soft plate can play a good anti-skid role, the clamping plate can be pushed up during the movement of the slide column, when the slide column stops moving, the second spring is pulled to make the two clamping plates move downward and be clamped into the clamping groove on the slide column, so as to achieve the purpose of locking the position of the slide column, prevent the clamping plate from affecting the stability of the test tube clamping, and thus the degree of test tube pressing is controlled to control the pressure in the piston cylinder, so as to adjust the position of the slide column and the clamping plate, and meet the purpose of clamping different specifications of test tubes. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1 It is a three-dimensional structural schematic diagram of the present application;

[0019] Figure 2 It is a partial sectional structural schematic diagram of the present application;

[0020] Figure 3 It is a structural schematic diagram of the partition plate and the material supporting assembly of the present application;

[0021] Figure 4 It is a structural schematic diagram of the material supporting assembly and the material supporting assembly of the present application;

[0022] Figure 5 It is a structural schematic diagram of the extrusion assembly of the present application;

[0023] Figure 6 It is a structural schematic diagram of the limiting assembly of the present application;

[0024] Figure 7 It is a structural schematic diagram of the positioning assembly of the present application;

[0025] Figure 8 It is a structural schematic diagram of the guiding assembly of the present application;

[0026] In the diagram: 1. Box body; 2. Support base; 3. Box cover; 4. Mounting assembly; 401. Chuck; 402. Placement hole; 403. Fixing post; 5. Test tube; 6. Material support assembly; 601. Rotary disk; 602. Bearing seat; 603. Limiting groove; 604. Locking hole; 7. Extrusion assembly; 701. Air cushion seat; 702. Pressure rod; 703. Air guide tube; 8. Limiting assembly; 801. Clamping plate; 802. Sliding column; 803. Piston cylinder; 804. First spring; 805. Locking groove; 806. Limiting block; 807. Slide rail; 9. Positioning assembly; 901. Dial ring; 902. Locking strip; 903. Second spring; 10. Guide assembly; 101. Micro motor; 102. Drive disk; 103. Dial rod; 11. Partition plate; 12. Retaining ring. Detailed Implementation

[0027] The technical solution of this application will be further described in detail below with reference to specific embodiments.

[0028] like Figures 1-8 As shown, the present invention provides a technical solution: a kit for detecting metabolites in exhaled condensate for lung disease detection, comprising a box body 1, a support base 2 at the bottom of the box body 1, a box cover 3 installed at the top of the box body 1, a retaining ring 12 overlapping the bottom of the box cover 3, the retaining ring 12 being snapped into the outer wall of the box body 1, a mounting assembly 4 inside the box body 1, the mounting assembly 4 comprising a chuck 401, the chuck 401 being disposed inside the box body 1, placement holes 402 being respectively opened on the chuck 401 corresponding to the positions of several test tubes 5, the test tubes 5 passing through the placement holes 402, three fixing posts 403 being fixedly connected to the bottom of the chuck 401, the bottom ends of the three fixing posts 403 being fixed to the material support assembly 6, because the multiple placement holes 402 are equidistantly arranged on the chuck 401, the multiple test tubes 5 can be placed separately, preventing friction damage between the multiple test tubes 5;

[0029] A number of test tubes 5 are installed on the support component 4. A material support component 6 is fixedly connected to the bottom end of the support component 4. The material support component 6 includes a rotating disk 601. The top of the rotating disk 601 is fixedly connected to the bottom end of the support component 4. Limiting grooves 603 are respectively opened on several protrusions on the outer wall of the rotating disk 601. The bottom end of the test tube 5 is engaged in the limiting groove 603. The protrusions on the outer wall of the rotating disk 601 are connected to the guide component 10. Because the limiting groove 603 is provided, and the limiting groove 603 is an arc surface design that can fit the bottom end of the test tube 5, it plays a role in providing stable support for the test tube 5.

[0030] The middle part of the rotating disc 601 is provided with a clamping hole 604, and a bearing seat 602 is arranged in the clamping hole 604. The bearing seat 602 is arranged on the partition plate 11. The rotating disc 601 is arranged at the bottom of the inner wall of the box body 1. Due to the bearing seat 602, the rotating disc 601 can rotate around the center of the bearing seat 602, thereby improving the stability of the rotating disc 601 in driving the erecting assembly 4 to rotate.

[0031] The bottom end of the plurality of test tubes 5 is clamped in the material supporting assembly 6. A plurality of extrusion assemblies 7 are equidistantly arranged on the material supporting assembly 6. The extrusion assembly 7 comprises a gas cushion seat 701 arranged at the bottom of the inner wall of the limiting groove 603. The gas cushion seat 701 is provided with a pressing rod 702. The top end of the pressing rod 702 is in contact with the bottom end of the test tube 5. The two sides of the gas cushion seat 701 are respectively connected with gas guide pipes 703. One end of the gas guide pipe 703 away from the gas cushion seat 701 is connected with one end of the limiting assembly 8. Due to the gas cushion seat 701, when the test tube 5 is inserted into the placement hole 402, the bottom end of the test tube 5 is in contact with the pressing rod 702. The pressing rod 702 can extrude the gas cushion seat 701 after being pressed. The gas cushion seat 701 can guide the gas into the piston cylinder 803 through the two gas guide pipes 703 after deformation. The piston cylinder 803 can push the slide column 802 to move with the increase of the gas pressure in the piston cylinder 803, thereby facilitating the adjustment of the position of the slide column 802 and the clamping plate 801.

[0032] The top end of the extrusion assembly 7 is connected with two limiting assemblies 8. The limiting assembly 8 comprises a clamping plate 801. The clamping plate 801 is a rubber soft plate and is designed in an arc shape. The inner wall of the clamping plate 801 is in contact with the outer wall of the test tube 5. The outer wall of the clamping plate 801 is fixedly connected with a slide column 802. The slide column 802 is sleeved with a piston cylinder 803. The piston cylinder 803 is clamped in the inner wall of the placement hole 402. The slide column 802 is sleeved with a first spring 804. One end of the first spring 804 is fixedly connected with the outer wall of the clamping plate 801. The other end of the first spring 804 is fixedly connected with the inner wall of the placement hole 402. Due to the first spring 804, the clamping plate 801 can be driven to move by the elastic force of the first spring 804, so that the clamping plate 801 can move away from the test tube 5. At the same time, the slide column 802 can guide the gas into the gas cushion seat 701 through the gas guide pipe 703 during the movement process, so that the gas cushion seat 701 can lift the pressing rod 702, thereby facilitating the removal of the test tube 5 and the installation of the test tube 5 next time.

[0033] The top part of the slide column 802 is provided with a plurality of clamping grooves 805. One of the clamping grooves 805 is clamped with the bottom end of the positioning assembly 9. The bottom part of the slide column 802 is fixedly connected with a limiting block 806. The bottom part of the inner wall of the piston cylinder 803 is provided with a slide way 807. The limiting block 806 is slidably connected in the slide way 807. Through the cooperation between the limiting block 806 and the slide way 807, the slide way 807 can support the limiting block 806, thereby preventing the slide column 802 from freely deflecting and affecting the stability of the clamping plate 801 in clamping the test tube 5.

[0034] The limiting assembly 8 is installed in the erecting assembly 4, opposite two limiting assemblies 8 are provided with positioning assemblies 9, the positioning assemblies 9 are connected to the erecting assembly 4, the positioning assembly 9 comprises a dial ring 901, two sides of the bottom of the dial ring 901 are fixedly connected with clamping strips 902, the clamping strips 902 are designed in L shape, and the bottom end of the clamping strip 902 is embedded in the erecting assembly 4 and clamped in the clamping groove 805, the bottom end of the clamping strip 902 is designed as a curved surface away from the position of the clamping plate 801, the second spring 903 is fixedly installed between the clamping strip 902 and the erecting assembly 4, due to the second spring 903, the dial ring 901 drives the two clamping strips 902 to move downward and be clamped into the clamping groove 805 on the sliding column 802 through the pulling force of the second spring 903, the purpose of locking the position of the sliding column 802 is realized, and the free movement of the clamping plate 801 is prevented to affect the clamping stability of the test tube 5;

[0035] The bottom of the material supporting assembly 6 is connected with a partition plate 11, the partition plate 11 is installed at the bottom of the box body 1, the lower portion of the partition plate 11 is provided with a guide assembly 10, the guide assembly 10 is installed in the supporting base 2, the guide assembly 10 comprises a micro motor 101, the micro motor 101 is installed in the supporting base 2, the output shaft of the micro motor 101 penetrates the partition plate 11 and the box body 1 and is connected with a driving disc 102, the driving disc 102 is provided with a dial lever 103 at the edge of the top portion, the dial lever 103 is in contact with the convex portion of the outer wall of the rotating disc 601, due to the dial lever 103, the cavity is formed between adjacent two convex portions, so that the dial lever 103 can push the rotating disc 601 to rotate in the rotating process, and the position of the test tube 5 on the erecting assembly 4 is adjusted conveniently;

[0036] The top end of the guide assembly 10 penetrates the bottom of the box body 1 and is connected to the outside of the material supporting assembly 6.

[0037] The working principle of the present application is as follows:

[0038] In use, the test tube 5 containing metabolites is placed on the chuck 401 in the box body 1, the test tube 5 is placed through the placement hole 402 and is in contact with the rotating disc 601, the bottom end of the test tube 5 is clamped into the limiting groove 603, and the pressing rod 702 is pushed, the pressing rod 702 can extrude the air cushion seat 701 after being pressed, the air cushion seat 701 can guide the gas into the piston cylinder 803 through the two gas guide pipes 703 after being deformed, the piston cylinder 803 can push the slide column 802 to move as the gas pressure in the piston cylinder 803 increases, the two clamping plates 801 are driven by the two slide columns 802 to clamp the outer wall of the test tube 5, the clamping strips 902 are pushed to move upward in the process that the slide column 802 moves, when the slide column 802 no longer moves, the clamping strips 902 are driven by the dial ring 901 to move downward and are clamped into the clamping grooves 805 on the slide column 802 under the action of the pulling force of the second spring 903, the position of the slide column 802 is locked, in the process of detecting the test tube 5 in the box body 1, the box body 1 is placed at the position of the external detection mechanism, the plurality of test tubes 5 correspond to the plurality of detection stations under the detection mechanism respectively, the micro motor 101 is controlled to work to drive the driving disc 102 to rotate, the driving disc 102 drives the dial rod 103 to rotate, the dial rod 103 can rotate outside the convex on the outer wall of the rotating disc 601, cavities are formed between adjacent two convexes, the dial rod 103 can drive the rotating disc 601 to rotate through the cavities in the rotating process, the rotating disc 601 can rotate around the center of the bearing seat 602, and the rotating disc 601 drives the plurality of test tubes 5 to rotate synchronously through the erecting assembly 4, the test tube 5 can be pushed to the next detection station after completing the current detection process, the dial rod 103 can drive the rotating disc 601 to rotate intermittently as the dial rod 103 continues to rotate, so as to synchronously adjust the positions of the plurality of test tubes 5, the test tube 5 in the box body 1 can be continuously detected, when the test tube 5 is taken out, the dial ring 901 is pulled to drive the two clamping strips 902 to move upward, the clamping strips 902 can be separated from the clamping grooves 805 on the slide column 802, the limiting of the slide column 802 is released, the clamping plates 801 can move away from the test tube 5 under the action of the elastic force of the first spring 804, and the slide column 802 can guide the gas into the air cushion seat 701 through the gas guide pipe 703 in the moving process, so that the air cushion seat 701 can lift the pressing rod 702, and the test tube 5 can be taken out.

[0039] In the description of the present application, it should be understood that the terms "center", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", "circumferential" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application.

[0040] In addition, the terms "first", "second", etc. are used only to describe the purpose and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined with "first", "second" can explicitly or implicitly include one or more of the features. In the description of the present application, the meaning of "a plurality of" is two or more, unless otherwise explicitly specified and limited.

[0041] In the present application, unless otherwise explicitly specified and limited, the terms "mounting", "connecting", "connecting", "fixing" and the like should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or it can be integrated; it can be mechanically connected, or it can be electrically connected, or it can be communicated; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication or interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0042] In the present application, unless otherwise explicitly specified and limited, the first feature is "on" or "under" the second feature, which can be direct contact between the first and second features, or indirect contact between the first and second features through an intermediate medium. In the description of the present application, the description of the reference terms "one scheme", "some schemes", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the scheme or example are included in at least one scheme or example of the present application. In the present application, the illustrative description of the above terms does not necessarily refer to the same scheme or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more schemes or examples in a suitable manner.

Claims

1. A kit for the detection of metabolites in exhaled breath condensate for the detection of lung diseases, comprising a box (1), characterized in that: The bottom of the box body (1) is provided with a supporting base (2), the top of the box body (1) is provided with a box cover (3), the bottom of the box cover (3) is overlapped with a blocking ring (12), the blocking ring (12) is clamped on the outer wall of the box body (1), the inside of the box body (1) is provided with a mounting assembly (4), a plurality of test tubes (5) are mounted on the mounting assembly (4), the bottom end of the mounting assembly (4) is fixedly connected with a material supporting assembly (6), the bottom end of the plurality of test tubes (5) is clamped in the material supporting assembly (6), a plurality of extrusion assemblies (7) are equidistantly arranged on the material supporting assembly (6); The top end of the extrusion assembly (7) is connected with two limiting assemblies (8), the limiting assemblies (8) are mounted in the mounting assembly (4), the opposite two limiting assemblies (8) are provided with a positioning assembly (9), the positioning assembly (9) is connected to the mounting assembly (4), the bottom of the material supporting assembly (6) is connected with a partition plate (11), the partition plate (11) is mounted on the bottom of the box body (1), the lower portion of the partition plate (11) is provided with a guide assembly (10), the guide assembly (10) is mounted in the supporting base (2), the top end of the guide assembly (10) penetrates through the bottom of the box body (1) and is connected to the outside of the material supporting assembly (6); The mounting assembly (4) comprises a chuck (401), the chuck (401) is arranged in the box body (1), a plurality of placing holes (402) are respectively arranged on the chuck (401) corresponding to the positions of the plurality of test tubes (5), the test tubes (5) penetrate through the placing holes (402), the bottom of the chuck (401) is fixedly connected with three fixed columns (403), the bottom end of the three fixed columns (403) is fixed to the material supporting assembly (6); The material supporting assembly (6) comprises a rotating disc (601), the top of the rotating disc (601) is fixedly connected with the bottom end of the mounting assembly (4), a plurality of limiting grooves (603) are respectively arranged on the protrusions of the outer wall of the rotating disc (601), the bottom end of the test tube (5) is clamped in the limiting groove (603), the protrusions of the outer wall of the rotating disc (601) are connected with the guide assembly (10); The extrusion assembly (7) comprises an air cushion seat (701), the air cushion seat (701) is mounted on the bottom of the inner wall of the limiting groove (603), the air cushion seat (701) is provided with a pressing rod (702), the top end of the pressing rod (702) is in contact with the bottom end of the test tube (5), the two sides of the air cushion seat (701) are respectively connected with air guide pipes (703), one end of the air guide pipe (703) away from the air cushion seat (701) is connected with one end of the limiting assembly (8). The limiting assembly (8) comprises a clamping plate (801), which is a rubber soft plate and is designed in an arc shape, the inner wall of the clamping plate (801) is attached to the outer wall of the test tube (5), the outer wall of the clamping plate (801) is fixedly connected with a sliding column (802), the sliding column (802) is sleeved with a piston cylinder (803), the piston cylinder (803) is clamped on the inner wall of the placement hole (402), the sliding column (802) is sleeved with a first spring (804), one end of the first spring (804) is fixedly connected with the outer wall of the clamping plate (801), the other end of the first spring (804) is fixedly connected with the inner wall of the placement hole (402). The positioning assembly (9) comprises a dial ring (901), the two sides of the bottom of the dial ring (901) are fixedly connected with clamping strips (902), the clamping strips (902) are designed in an L shape, the bottom end of the clamping strips (902) is embedded in the erecting assembly (4) and is clamped in the clamping groove (805), the bottom end of the clamping strips (902) is designed in an arc surface away from the clamping plate (801), the clamping strips (902) and the erecting assembly (4) are fixedly installed with a second spring (903).

2. The kit of reagents for detecting metabolites in exhaled breath condensate for detection of lung disease according to claim 1, characterized in that: The middle part of the rotating disc (601) is provided with a clamping hole (604), the clamping hole (604) is installed with a bearing seat (602), the bearing seat (602) is arranged on the partition plate (11), and the rotating disc (601) is installed at the bottom of the inner wall of the box body (1).

3. The kit of claim 1, wherein the kit is for the detection of lung disease. The top of the sliding column (802) is provided with a plurality of clamping grooves (805), one of the clamping grooves (805) is clamped with the bottom end of the positioning assembly (9), the bottom of the sliding column (802) is fixedly connected with a limiting block (806), the inner wall of the piston cylinder (803) is provided with a sliding channel (807) at the bottom, and the limiting block (806) is slidably connected in the sliding channel (807).

4. The kit of claim 1, wherein the kit is for the detection of lung disease. The guide assembly (10) comprises a micro motor (101), the micro motor (101) is installed in the supporting base (2), the output shaft of the micro motor (101) penetrates the partition plate (11) and the box body (1) and is connected with a driving disc (102), the edge of the top of the driving disc (102) is provided with a dial lever (103), and the dial lever (103) is in contact with the protrusions of the outer wall of the rotating disc (601).

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