Edge cutting and skin-like tissue frozen section embedding device

Abstract

Relates to the field of medical equipment, and discloses an incisal edge and capsule skin tissue frozen section embedding device which comprises an embedding bracket and further comprises an extrusion belt arranged in the embedding bracket and used for extruding and limiting the position of a tissue sample in the embedding bracket; the mounting bracket is adjustably arranged in the embedding bracket, is connected with the extrusion belt and is used for supporting the extrusion belt; the height adjusting device is arranged on the mounting bracket, is connected with the extrusion belt and is used for adjusting the mounting height of the extrusion belt; the width adjusting device is arranged on the height adjusting device, connected with the extrusion belt and used for adjusting the width of the extrusion belt, it is ensured that the position of a sample is stable in the embedding process, the embedded tissue sample is smoother, and the integrity and uniformity of tissue sample slices are ensured.

Description

Technical Field

[0001] The invention relates to the technical field of medical equipment, in particular to a cutting edge and cystoid tissue frozen section embedding device. Background Art

[0002] In the field of biomedical research, especially in pathology, histology and related clinical diagnosis, frozen section technology is an important experimental method. This technology uses a quick freezing of tissue samples and then uses a slicer to make thin slices for microscopic observation and analysis. However, during the tissue embedding process before slicing, how to ensure the stability of the position of the tissue sample, the preservation of its morphology, and the convenience of operation during slicing have always been the focus of technicians.

[0003] The existing equipment has the following disadvantages: It is currently difficult to cut the entire incision edge, cyst wall and capsule. Due to the irregular shape of the incision edge and cyst wall specimen tissue and the thin tissue capsule, it is difficult to achieve effective embedding and positioning through a simple mold, resulting in uneven embedding of the incision edge and cyst skin-like tissue, and incomplete slicing of the cyst wall, incision edge and capsule.

[0004] Therefore, the present application proposes a cutting edge and cystoid tissue frozen section embedding device to solve the above-mentioned problems. Summary of the invention

[0005] The object of the present invention is to provide a cutting edge and cystodermoid tissue frozen section embedding device to solve the above-mentioned problem of uneven embedding of cutting edge and cystodermoid tissue and incomplete tissue sectioning.

[0006] To achieve the above object, the present invention provides the following technical solution: a device for embedding frozen sections of cutting edge and cystic skin-like tissue, comprising an embedding bracket, and further comprising: A squeezing belt, arranged inside the embedding bracket, for squeezing and limiting the position of the tissue sample inside the embedding bracket; A mounting bracket, which is adjustably arranged inside the embedding bracket and connected to the extrusion belt, and is used to support the extrusion belt; A height adjustment device, disposed on the mounting bracket and connected to the extrusion belt, for adjusting the mounting height of the extrusion belt; A width adjustment device is arranged on the height adjustment device and connected to the extrusion belt, and is used for adjusting the width of the extrusion belt.

[0007] Among them, the width adjustment device includes a power part fixed on both sides of the height adjustment device, a connecting block arranged at the power output end of the power part, a mounting frame arranged on the side of the connecting block away from the power part, and a fixed shaft fixed on the mounting frame, a winding roller is sleeved on the fixed shaft, and the extrusion belt is wound on the winding roller.

[0008] Wherein, an elastic member is arranged between the fixed shaft and the winding roller.

[0009] Wherein, the power member is symmetrically arranged with respect to the height adjustment device.

[0010] Wherein, the height adjustment device comprises a screw rod threadedly connected to the mounting bracket, a turntable fixed to the upper end of the screw rod and a lifting plate fixed to the lower end of the screw rod, and the power member is fixed on the lifting plate.

[0011] Wherein, a guide rod is fixed to the upper end of the lifting plate, and the guide rod passes through the mounting bracket.

[0012] Among them, the mounting bracket includes a support frame placed in the embedded bracket, a cross-shaped support plate fixed on the inner side of the support frame, and a mounting plate fixed in the middle of the support plate. The screw is threadedly connected to the mounting plate, and a through hole is opened on the support plate at the position corresponding to the guide rod for the movement of the guide rod.

[0013] Wherein, the extrusion belt is provided with through holes.

[0014] The embedding bracket comprises a material storage frame for storing tissue samples and side ears fixed on the upper end of the material storage frame, and the squeezing belt is adjustably arranged inside the material storage frame.

[0015] The upper end of the material storage frame is provided with a placement groove for placing the support frame, and the interior of the material storage frame is provided with a storage groove, the cross-section of the storage groove is trapezoidal, and the support frame abuts against the inner wall of the placement groove.

[0016] Compared with the prior art, the present invention has the following beneficial effects: The present invention introduces an extrusion belt, a mounting bracket, a height adjustment device and a width adjustment device, so that the device can achieve accurate positioning and stable embedding of tissue samples. The extrusion belt can be flexibly adjusted according to the shape and size of the tissue sample to ensure the stability of the position of the sample during the embedding process, making the embedded tissue sample flatter, and ensuring the integrity and uniformity of the tissue sample slices. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic diagram of the main structure in one embodiment of the present invention; Figure 2 It is a schematic diagram of a top view of a structure in one embodiment of the present invention; Figure 3 It is a schematic structural diagram of an embodiment of the present invention in a front view; Figure 4 It is a schematic diagram of a cross-section structure in one embodiment of the present invention; Figure 5 It is a schematic diagram of the structure of explosion in one embodiment of the present invention; Figure 6 It is a schematic diagram of the structure in which an extrusion belt is connected to a width adjustment device in one embodiment of the present invention; Figure 7 It is a structural schematic diagram of a mounting bracket in one embodiment of the present invention; Figure 8 It is a structural schematic diagram of a mounting frame in one embodiment of the present invention; Fig. 9 It is a schematic structural diagram of a width adjustment device for adjusting the width of an extruded belt in one embodiment of the present invention; Fig.10 It is a schematic structural diagram of a width adjustment device for adjusting the moving direction of the extruded belt width in one embodiment of the present invention; Fig.11 for Figure 8 The enlarged structural diagram of the middle A part; Fig.12 It is a schematic diagram of the structure of a freezing hammer freezing a sample in a grinding tool disk in one embodiment of the present invention; Fig.13 It is a schematic diagram of the structure of a freezing hammer performing freezing sectioning on a sample in a grinding tool disk in one embodiment of the present invention; Fig.14 It is a schematic diagram of the structure of the connection between the mold plate and the embedding tray in one embodiment of the present invention; Fig.15 A schematic structural diagram of the threaded hole installation position in one embodiment of the present invention.

[0018] In the figure: 1. embedding bracket; 101. placement slot; 102. storage slot; 103. threaded hole; 11. side ear; 12. storage frame; 2. mounting bracket; 21. support frame; 22. support plate; 2201. perforation; 23. mounting plate; 3. extrusion belt; 31. positioning ring; 4. height adjustment device; 41. screw; 42. turntable; 43. lifting plate; 44. guide rod; 5. width adjustment device; 51. power part; 52. connecting block; 53. mounting frame; 54. fixed shaft; 55. winding roller; 56. elastic part; 6. freezing hammer; 7. mold plate; 71. sample slot. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Example

[0020] See also Figure 1-11 The present invention provides a technical solution: a cutting edge and cystoid tissue frozen section embedding device, comprising an embedding bracket 1, and also comprising: The squeezing belt 3 is arranged inside the embedding bracket 1 and is used to squeeze and limit the position of the tissue sample inside the embedding bracket 1; A positioning ring 31 is provided at the upper end of the extrusion belt 3; A mounting bracket 2, which is adjustably arranged inside the embedding bracket 1 and connected to the extrusion belt 3, and is used to support the extrusion belt 3; A height adjustment device 4, which is arranged on the mounting bracket 2 and connected to the extrusion belt 3, and is used to adjust the installation height of the extrusion belt 3; The width adjusting device 5 is arranged on the height adjusting device 4 and connected to the extrusion belt 3 , and is used for adjusting the width of the extrusion belt 3 .

[0021] It should be noted that, during operation, the tissue surface to be inspected is selected, and then the tissue surface is placed inside the embedding bracket 1, and then the extrusion belt 3 is placed inside the embedding bracket 1, and the position of the extrusion belt 3 in the embedding bracket 1 is adjusted by the height adjustment device 4. When the lower end of the extrusion belt 3 contacts the tissue sample, the width of the extrusion belt 3 is adjusted by the width adjustment device 5, so that the extrusion belt 3 can abut against the inner wall of the embedding bracket 1, and the size of the extrusion belt 3 is adjusted according to the size of the tissue sample. When the tissue sample is large, the height of the extrusion belt 3 from the bottom of the embedding bracket 1 is higher, and the width of the extrusion belt 3 is wider at this time, and then liquid OCT glue is dripped into the inside of the embedding bracket 1, and the liquid OCT glue drop is filled to be flush with the bottom end of the extrusion belt 3, and then the embedding bracket 1 is placed on the freezing zone of the freezing microtome for freezing, and the freezing hammer 6 is placed in the positioning ring 31 at the upper end of the extrusion belt 3 to cool the OCT glue drop and the sample inside the embedding bracket 1, and then the sample cooling is completed after more than ten seconds. , then take out the freezing hammer 6 from the inside of the positioning ring 31, take out the mounting bracket 2 from the embedding bracket 1, and then remove the squeezing belt 3 from the tissue sample embedding block together with the mounting bracket 2, and then place the embedding mold inside the embedding bracket 1 and on the tissue sample embedding block, and then drip liquid OCT glue into the inside of the embedding bracket 1 until it is full, and then place the embedding bracket 1 on the freezing zone of the freezing slicer for freezing, and then after the freezing is completed, take out the tissue sample embedding block from the embedding bracket 1 and place it on the slicer for slicing. By introducing the squeezing belt 3, the mounting bracket 2, the height adjustment device 4 and the width adjustment device 5, the device can realize accurate positioning and stable embedding of the tissue sample, thereby realizing rapid cooling and freezing fixation of the cystic skin tissue sample, and the squeezing belt 3 can be flexibly adjusted according to the shape and size of the tissue sample to ensure the stable position of the sample during the embedding process, so that the embedded tissue sample is more flat, and the integrity and uniformity of the tissue sample slices are ensured.

[0022] In one embodiment, the width adjustment device 5 includes a power member 51 fixed on both sides of the height adjustment device 4, a connecting block 52 arranged at the power output end of the power member 51, a mounting frame 53 arranged on the side of the connecting block 52 away from the power member 51, and a fixed shaft 54 ​​fixed on the mounting frame 53, a winding roller 55 is sleeved on the fixed shaft 54, and the extruded belt 3 is wound on the winding roller 55, and the power member 51 includes but is not limited to a cylinder, an electric push rod, and a linear guide rail.

[0023] This design, see Figure 5-11By driving the power member 51, the connecting block 52 can drive the mounting frame 53 and the winding roller 55 on the fixed shaft 54 ​​to move, thereby realizing flexible adjustment of the width of the extrusion belt 3. This design enables the device to adjust the width of the extrusion belt 3 according to the size of the tissue sample, so that the extrusion belt 3 can fix the tissue sample more firmly, realize accurate positioning and stable embedding of the tissue sample, and improve the versatility and flexibility of the device.

[0024] In one embodiment, an elastic member 56 is provided between the fixed shaft 54 ​​and the winding roller 55 . The elastic member 56 is made of a clockwork spring and is sleeved on the fixed shaft 54 ​​, and a section of the elastic member 56 is detachably fixed between the fixed shaft 54 ​​and the winding roller 55 .

[0025] This design, see Fig.11 When the extrusion belt 3 is stretched, it will drive the winding roller 55 to rotate on the fixed shaft 54, so that the winding roller 55 unwinds the extrusion belt 3. At this time, the winding roller 55 stretches the elastic member 56. When the winding roller 55 drives the extrusion belt 3 to rewind, the elastic member 56 is reset, which can drive the extrusion belt 3 to automatically rewind, making it convenient to rewind the extrusion belt 3.

[0026] In one embodiment, the power member 51 is symmetrically arranged with respect to the height adjustment device 4 .

[0027] This design, see Figure 6 The symmetrically arranged power members 51 can ensure that the forces generated on both sides are balanced when the width is adjusted, thereby avoiding the tilting of the tissue sample when the squeezing belt 3 squeezes and fixes the tissue sample due to uneven width adjustment on both sides of the squeezing belt 3.

[0028] In one embodiment, the height adjustment device 4 includes a screw rod 41 threadedly connected to the mounting bracket 2 , a turntable 42 fixed to the upper end of the screw rod 41 , and a lifting plate 43 fixed to the lower end of the screw rod 41 , and the power member 51 is fixed to the lifting plate 43 .

[0029] This design, see Figure 5 ,as well as Figure 6 By rotating the turntable 42, the screw 41 can be driven to rotate on the mounting bracket 2 and move along its axial direction, thereby realizing the height adjustment of the lifting plate 43 and the power member 51 fixed thereon and subsequent components. This design provides precise height adjustment capability and can meet the needs of fixing tissue samples of different sizes.

[0030] In one embodiment, a guide rod 44 is fixed to the upper end of the lifting plate 43 , and the guide rod 44 passes through the mounting bracket 2 .

[0031] This design, see Figure 5-8The guide rod 44 provides an additional support point for the lifting plate 43, which helps prevent the lifting plate 43 from deflecting or shaking during the lifting process, thereby enhancing the stability of the entire device.

[0032] In one embodiment, the mounting bracket 2 includes a support frame 21 placed in the embedded bracket 1, a cross-shaped support plate 22 fixed to the inner side of the support frame 21, and a mounting plate 23 fixed to the middle of the support plate 22. The screw 41 is threadedly connected to the mounting plate 23, and a through hole 2201 is opened at the position of the support plate 22 corresponding to the guide rod 44 for the guide rod 44 to move.

[0033] This design, see Figure 4-8 ,as well as Figure 2 The support frame 21 is docked with the inner wall of the embedding bracket 1, so that the support frame 21 can be firmly fixed inside the embedding bracket 1. The cross-shaped design enables the support plate 22 to provide stable supporting force in both horizontal and vertical directions, effectively preventing the mounting bracket 2 from deforming or tilting when subjected to force. The perforation 2201 can increase the moving space for the guide rod 44, and the support frame 21 can be adjusted according to the size of the embedding bracket 1, so as to quickly and accurately fix the position of the extrusion belt 3, thereby greatly improving the work efficiency.

[0034] In one embodiment, the extrusion belt 3 is provided with through holes.

[0035] This design, see Figure 5-6 ,as well as Figure 8-9 The through holes on the extrusion belt 3 can facilitate the liquid OCT glue droplets to flow into the tissue sample in the embedding bracket 1 to embed the tissue sample.

[0036] In one embodiment, the embedding bracket 1 comprises a storage frame 12 for storing tissue samples and side ears 11 fixed to the upper end of the storage frame 12 , and the pressing belt 3 is adjustably arranged inside the storage frame 12 .

[0037] This design, see Figure 1-5 The side ears 11 can facilitate taking the embedding bracket 1, and the storage frame 12 is used to store tissue samples and liquid OCT glue drops. The squeezing belt 3 can adjust the position of the squeezing belt 3 in the storage frame 12 according to the size of the tissue sample inside the storage frame 12, so that the lower end of the squeezing belt 3 is docked with the tissue sample to squeeze and fix the tissue sample.

[0038] In one embodiment, a placement groove 101 for placing the support frame 21 is opened at the upper end of the material storage frame 12, and a storage groove 102 is opened inside the material storage frame 12. The cross-section of the storage groove 102 is trapezoidal, and the support frame 21 abuts against the inner wall of the placement groove 101.

[0039] This design, see Figure 4 ,as well as Figure 5 The design of the placement slot 101 enables the support frame 21 to be tightly embedded therein, thereby providing a stable support, helping to prevent the support frame 21 from shifting or tilting during operation, and ensuring the stability of the entire embedding bracket 1. The setting of the storage slot 102 can meet the needs of fixing tissue samples of different sizes, and it is convenient to remove the embedded tissue samples from the storage slot 102. Example

[0040] In one embodiment, a threaded hole 103 is provided in the middle of the embedding bracket 1, and the mold plate 7 is threadedly connected to the inner part of the threaded hole 103. The upper end of the mold plate 7 is provided with a sample groove 71 for placing the sample.

[0041] This design, see Figure 12-15 , take out the mounting bracket 2 and the extrusion belt 3 from the embedding bracket 1, then thread the mold plate 7 into the threaded hole 103, then place the tissue sample in the sample slot 71, insert the lower end of the mold plate 7 into the mounting slot of the freezer, and insert the lower end of the freezing hammer 6 into the placement slot 101 at the upper end of the embedding bracket 1. By adjusting the distance between the sample slot 71 and the placement slot 101, the freezing of tissue samples of different sizes can be satisfied. When the size of the tissue sample is small, the distance between the sample slot 71 and the placement slot 101 is reduced, and vice versa. The lower end of the freezing hammer 6 contacts the sample in the sample slot 71 and freezes the tissue sample. After freezing, take out the mold plate 7 and the embedding bracket 1 from the mounting slot of the freezer, and fix the lower part of the mold plate 7 on the slicer for slicing. By setting the device, the freezing of tissue samples can be quickly realized, and a variety of tissue sample freezing methods are set to improve the applicability of the entire tissue frozen section embedding device.

Claims

1. A device for embedding frozen sections of cutting edge and cystoid tissue, comprising an embedding bracket (1), characterized in that: Also includes: A squeezing belt (3) is arranged inside the embedding bracket (1) and is used to squeeze and limit the position of the tissue sample inside the embedding bracket (1); A mounting bracket (2) is adjustably arranged inside the embedding bracket (1) and connected to the extrusion belt (3), and is used to support the extrusion belt (3); A height adjustment device (4), arranged on the mounting bracket (2) and connected to the extrusion belt (3), and used for adjusting the installation height of the extrusion belt (3); A width adjustment device (5) is arranged on the height adjustment device (4) and connected to the extrusion belt (3), and is used to adjust the width of the extrusion belt (3).

2. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 1, characterized in that: The width adjustment device (5) comprises power members (51) fixed on both sides of the height adjustment device (4), a connecting block (52) arranged at a power output end of the power member (51), a mounting frame (53) arranged on a side of the connecting block (52) away from the power member (51), and a fixed shaft (54) fixed to the mounting frame (53), wherein a winding roller (55) is sleeved on the fixed shaft (54), and the extruded belt (3) is wound on the winding roller (55).

3. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 2, characterized in that: An elastic member (56) is provided between the fixed shaft (54) and the winding roller (55).

4. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 2, characterized in that: The power member (51) is arranged symmetrically with respect to the height adjustment device (4).

5. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 2, characterized in that: The height adjustment device (4) comprises a screw rod (41) threadedly connected to the mounting bracket (2), a rotating disk (42) fixed to the upper end of the screw rod (41), and a lifting plate (43) fixed to the lower end of the screw rod (41), and the power member (51) is fixed to the lifting plate (43).

6. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 5, characterized in that: A guide rod (44) is fixed to the upper end of the lifting plate (43), and the guide rod (44) passes through the mounting bracket (2).

7. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 6, characterized in that: The mounting bracket (2) comprises a support frame (21) placed in the embedding bracket (1), a cross-shaped support plate (22) fixed to the inner side of the support frame (21), and a mounting plate (23) fixed to the middle of the support plate (22), the screw rod (41) being threadedly connected to the mounting plate (23), and a through hole (2201) for the guide rod (44) to move is provided on the support plate (22) at a position corresponding to the guide rod (44).

8. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 1, characterized in that: The extrusion belt (3) is provided with through holes.

9. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 7, characterized in that: The embedding bracket (1) comprises a storage frame (12) for storing tissue samples and a side ear (11) fixed to the upper end of the storage frame (12), and the pressing belt (3) is adjustably arranged inside the storage frame (12).

10. The device for embedding frozen sections of cutting edge and cystoid tissue according to claim 9, characterized in that: The upper end of the material storage frame (12) is provided with a placement groove (101) for placing the support frame (21), and the interior of the material storage frame (12) is provided with a storage groove (102), the cross section of the storage groove (102) is arranged in a trapezoidal shape, and the support frame (21) abuts against the inner wall of the placement groove (101).

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