Local analgesic microneedle device for neuropathic pain

The microneedle device with a servo motor and bevel gear mechanism addresses the inconvenience and slow analgesic effects of existing treatments by enabling rapid and precise analgesic delivery for neuropathic pain.

CN119113324APending Publication Date: 2024-12-13SHIHEZI UNIVERSITY
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202411168663.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-08-23
Publication Date
2024-12-13

AI Technical Summary

Technical Problem

Existing local analgesic treatments for neuropathic pain are inconvenient and have slow analgesic effects.

Method used

A microneedle device with an integrated microneedle injection drive mechanism and drug injection mechanism, utilizing a servo motor and bevel gears to automatically penetrate and withdraw microneedles for precise analgesic delivery.

Benefits of technology

Facilitates convenient and rapid analgesic delivery by automatically injecting and withdrawing microneedles, enhancing the speed and efficacy of pain relief for neuropathic pain.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119113324A_ABST
    Figure CN119113324A_ABST
Patent Text Reader

Abstract

The invention discloses a local analgesic microneedle device for neuropathic pains, relates to the technical field of analgesic microneedle instruments, and provides the following scheme that the local analgesic microneedle device comprises a middle-section shell, the rear end of the middle-section shell is fixedly connected with a rear-section shell, and the front end of the middle-section shell is fixedly connected with a glass supporting cover; a microneedle injection driving mechanism is arranged in an inner cavity of the middle-section shell, a medicament injection mechanism penetrating into the glass supporting cover is arranged on the surface of the top of the middle-section shell, and a dry battery pack is fixedly connected into an inner cavity of the rear-section shell. According to the technical scheme, the micro-needle injection driving mechanism is arranged in the middle shell, the micro-needle can automatically pierce into an area needing local analgesia, the reciprocating type driving mechanism can rapidly withdraw after the micro-needle pierces and injects analgesic medicine, meanwhile, the medicine injection mechanism is arranged outside the middle shell, and the micro-needle injection driving mechanism can automatically pierce into the area needing local analgesia. And the analgesic medicament is conveyed into the needle head by matching the needle cylinder and the piston.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention relates to the technical field of analgesic microneedle instruments, and in particular to a local analgesic microneedle device for neuropathic pain. Background Art

[0002] Neuropathic pain can be a burning or tingling sensation, or it can manifest as an oversensitivity to touch and cold. Hypersensitivity to touch is called allodynia. Even light touch can cause pain. Sometimes neuropathic pain is deep and painful. If pain occurs during movement, the patient may be reluctant to move the painful part of the body. In this case, the muscles that control the painful area may become weak and movement may be more restricted. Because the structure of the nervous system has changed, making these structures more sensitive to pain, pain will still be felt long after the cause is resolved. When neuropathic pain occurs, neuropathic pain can be alleviated by administering analgesics (painkillers), which can reduce the severity of pain. Therefore, those skilled in the art hereby propose a local analgesic microneedle device for neuropathic pain. Summary of the invention

[0003] In view of the defects of the above-mentioned background technology that local analgesia is not convenient enough and has a slow analgesic effect when treating epileptic neuropathic pain, a technical solution of a microneedle device for local analgesia of neuropathic pain is provided; the device comprises a middle shell, the rear end of the middle shell is fixedly connected to the rear shell, the front end of the middle shell is fixedly connected to the glass support cover, a microneedle injection drive mechanism is arranged in the inner cavity of the middle shell, a drug injection mechanism penetrating into the interior of the glass support cover is arranged on the top surface of the middle shell, and a dry cell battery pack is fixedly connected in the inner cavity of the rear shell;

[0004] The drug injection mechanism includes a transparent syringe, a guide hose fixed to the front end of the transparent syringe, and a connecting block connected to the end of the guide hose and located inside the glass support cover, and a needle is screwed and fixed to the front end of the connecting block, and a force transmission cylinder located in the inner cavity of the middle shell is fixedly connected to the rear end of the connecting block; wherein a piston is movably arranged inside the transparent syringe, and a piston rod is fixedly connected to the rear end of the piston and penetrates the outside of the transparent syringe;

[0005] The microneedle injection drive mechanism includes a servo motor, a rotating shaft fixedly connected to the output shaft of the servo motor through a coupling, and a sleeve sleeved on the outer ring of the rotating shaft, and the end of the rotating shaft away from the servo motor is fixedly connected to the first bevel gear, the side of the first bevel gear is meshed with the second bevel gear, and a cylinder deviating from the center of the second bevel gear is fixed to the outer surface of the second bevel gear, wherein an annular groove is provided on the inner cavity side wall of the sleeve, and the end of the cylinder away from the second bevel gear is inserted into the annular groove for coupling.

[0006] In the technical solution of the above-mentioned local analgesic microneedle device for neuropathic pain, preferably, the top surface of the servo motor is fixedly connected to the top surface of the inner cavity of the middle section shell, and the middle section shell and the rotor of the servo motor are coaxially arranged, wherein the bottom surface of the inner cavity of the middle section shell is fixedly connected to a support frame, and the top end of the support frame is fixed with a bearing adapted to the rotating shaft.

[0007] In the technical solution of the above-mentioned local analgesic microneedle device for neuropathic pain, preferably, a support seat is fixed to the bottom surface of the inner cavity of the middle shell, and the rear side of the support seat is rotatably connected to a transmission shaft, and the rear end of the transmission shaft passes through the sleeve and is fixedly connected to the front end surface of the first bevel gear.

[0008] In the technical solution of the above-mentioned local analgesic microneedle device for neuropathic pain, preferably, the left and right end faces of the sleeve are respectively provided with circular holes for the transmission shaft and the rotating shaft to pass through, wherein a gap of 1mm-3mm is provided between the outer ring surface of the sleeve and the inner cavity side wall of the middle section shell, so as to allow the sleeve to be driven by the second bevel gear to reciprocate back and forth.

[0009] In the above-mentioned technical solution of a local analgesic microneedle device for neuropathic pain, preferably, the front end face of the sleeve is rotatably connected to a movable cylinder, and the front end face of the movable cylinder is fixedly connected to the rear end of the force transmission cylinder located in the inner cavity of the middle shell, wherein a protrusion is fixedly connected to the top surface of the movable cylinder, and a sliding groove is provided on the top surface of the inner cavity of the middle shell, the protrusion is inserted into the sliding groove for sliding connection, and the bottom surface of the outer ring of the movable cylinder is opened and closed with an opening for the support seat to pass through.

[0010] In the technical solution of the local analgesic microneedle device for neuropathic pain, preferably, the end of the cylinder away from the second bevel gear is fixedly connected to a slider, and the end of the slider away from the cylinder is located inside the annular groove.

[0011] In the technical solution of the above-mentioned local analgesic microneedle device for neuropathic pain, preferably, the front end face of the middle section shell is provided with a through hole for the force transmission cylinder to pass through and move back and forth, and the rear end of the glass support cover is fixedly connected to the front end of the middle section shell and covers the connecting block and the needle, wherein the length of the glass support cover is 1cm-2cm longer than the length of the needle.

[0012] In the technical solution of the above-mentioned local analgesic microneedle device for neuropathic pain, preferably, the bottom surface of the transparent syringe is fixed to the top surface of the outer ring of the middle shell, and the top surface of the outer ring of the transparent syringe is provided with a capacity scale, wherein a syringe end cover is fixed on the outer ring of the end of the piston rod away from the piston, and mutually matching threads are provided on the inner cavity side wall of the syringe end cover and the rear end outer ring surface of the transparent syringe, and a handle is also fixed on the rear end end of the piston rod.

[0013] In the technical solution of the above-mentioned local analgesic microneedle device for neuropathic pain, preferably, the interior of the connecting block has a chamber that penetrates the inner cavity of the needle, and the top surface of the connecting block is provided with a through hole for the guide hose to pass through and be fixed, wherein the top surface of the outer ring of the glass support cover is provided with a through hole for the guide hose to pass through.

[0014] In the technical solution of the above-mentioned local analgesic microneedle device for neuropathic pain, preferably, a control button is provided on the outer ring surface of the rear section shell, a power control mainboard is provided in the inner cavity of the rear section shell, and a charging port for charging the dry battery pack is provided on the rear end face of the rear section shell.

[0015] It can be seen from the above technical solution that the present invention provides a local analgesic microneedle device for neuropathic pain. Compared with the prior art, the present invention has the following beneficial effects:

[0016] In this technical solution, a microneedle injection drive mechanism is arranged inside the middle section of the shell, so that the microneedle can automatically penetrate into the area where local analgesia is required, and the reciprocating drive mechanism can quickly withdraw after the microneedle penetrates and injects the analgesic agent. At the same time, a drug injection mechanism is arranged outside the middle section of the shell, and the analgesic agent is delivered to the needle tip by using the syringe and piston in combination. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces and describes the drawings required for use in the embodiments of the present invention or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention, and for ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0018] Figure 1 This is an overall schematic diagram of the local analgesia microneedle device;

[0019] Figure 2 Schematic diagram of the local analgesia microneedle device after cutting;

[0020] Figure 3 This is a schematic diagram of the drug injection mechanism above the local analgesia microneedle device;

[0021] Figure 4 Schematic diagram of the microneedle injection drive mechanism.

[0022] Attached Figure 1 -Attached Figure 4 The corresponding relationship of the parts is as follows:

[0023] 1. Middle section shell; 2. Drug injection mechanism; 21. Transparent syringe; 22. Guide hose; 23. Needle; 24. Connecting block; 25. Force transmission cylinder; 26. Piston; 27. Syringe end cover; 28. Piston rod; 3. Rear section shell; 4. Dry cell battery pack; 5. Microneedle injection drive mechanism; 51. Servo motor; 52. Bearing; 53. Rotating shaft; 54. Annular slide; 55. Sleeve; 56. First bevel gear; 57. Bump; 58. Movable cylinder; 59. Support seat; 510. Transmission shaft; 511. Second bevel gear; 512. Cylinder; 513. Support frame; 6. Glass support cover. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described below are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0025] In order to more clearly explain and illustrate the technical solution and implementation of the present invention, several preferred specific embodiments for implementing the technical solution of the present invention are introduced below.

[0026] Embodiment: A preferred technical solution of a microneedle device for local analgesia of neuropathic pain:

[0027] It comprises a middle section shell 1, the rear end of the middle section shell 1 is fixedly connected to the rear section shell 3, the front end of the middle section shell 1 is fixedly connected to the glass support cover 6, and a micro-needle injection drive mechanism 5 is arranged in the inner cavity of the middle section shell 1, the top surface of the middle section shell 1 is arranged with a drug injection mechanism 2 which penetrates into the interior of the glass support cover 6, and a dry battery pack 4 is fixedly connected in the inner cavity of the rear section shell 3; the drug injection mechanism 2 comprises a transparent syringe 21, a guide hose 22 fixed to the front end of the transparent syringe 21, and a connecting block 24 connected to the end of the guide hose 22 and located in the interior of the glass support cover 6, and a needle 23 is screwed and fixed at the front end of the connecting block 24, and a force transmission cylinder 25 located in the inner cavity of the middle section shell 1 is fixedly connected to the rear end of the connecting block 24; wherein, a piston 26 is movably arranged in the interior of the transparent syringe 21, and a piston rod 28 which penetrates into the outside of the transparent syringe 21 is fixedly connected to the rear end of the piston 26;

[0028] The microneedle injection drive mechanism 5 includes a servo motor 51, a rotating shaft 53 fixedly connected to the output shaft of the servo motor 51 through a coupling, and a sleeve 55 sleeved on the outer ring of the rotating shaft 53, and the end of the rotating shaft 53 away from the servo motor 51 is fixedly connected to the first bevel gear 56, the side of the first bevel gear 56 is meshed with the second bevel gear 511, and the outer surface of the second bevel gear 511 is fixed with a cylinder 512 deviating from the center of the second bevel gear 511, wherein an annular groove 54 is opened on the inner cavity side wall of the sleeve 55, and the end of the cylinder 512 away from the second bevel gear 511 is inserted into the annular groove 54 for coupling.

[0029] The top surface of the servo motor 51 is fixedly connected to the top surface of the inner cavity of the middle section housing 1, and the middle section housing 1 and the rotor of the servo motor 51 are coaxially arranged, wherein a support frame 513 is fixedly connected to the bottom surface of the inner cavity of the middle section housing 1, and a bearing 52 adapted to the rotating shaft 53 is fixed to the top of the support frame 513. A support seat 59 is fixed to the bottom surface of the inner cavity of the middle section housing 1, and a transmission shaft 510 is rotatably connected to the rear side of the support seat 59, and the rear end of the transmission shaft 510 passes through the sleeve 55 and is fixedly connected to the front end surface of the first bevel gear 56.

[0030] The left and right side end faces of the sleeve 55 are respectively provided with round holes for the transmission shaft 510 and the rotating shaft 53 to pass through, wherein there is a gap of 1mm-3mm between the outer ring surface of the sleeve 55 and the inner cavity side wall of the middle section housing 1, so that the sleeve 55 can be driven by the second bevel gear 511 to reciprocate forward and backward. The front end face of the sleeve 55 is rotatably connected with a movable cylinder 58, and the front end face of the movable cylinder 58 is fixedly connected with the rear end of the force transmission cylinder 25 located in the inner cavity of the middle section housing 1, wherein the top surface of the movable cylinder 58 is fixedly connected with a protrusion 57, and the top surface of the inner cavity of the middle section housing 1 is provided with a slide groove, and the protrusion 57 is inserted into the slide groove for sliding connection, and the outer ring bottom surface of the movable cylinder 58 is opened and closed with an opening for the support seat 59 to pass through.

[0031] The end of the cylinder 512 away from the second bevel gear 511 is fixedly connected with a slider, and the end of the slider away from the cylinder 512 is located inside the annular slide groove 54. The front end surface of the middle section housing 1 is provided with a through hole for the force transmission cylinder 25 to penetrate and move forward and backward, and the rear end of the glass support cover 6 is fixedly connected to the front end of the middle section housing 1 and covers the connecting block 24 and the needle 23, wherein the length of the glass support cover 6 is 1cm-2cm longer than the length of the needle 23. The bottom surface of the transparent syringe 21 is fixed to the top surface of the outer ring of the middle section housing 1, and the top surface of the outer ring of the transparent syringe 21 is provided with a capacity scale, wherein a syringe end cover 27 is fixed on the outer ring of one end of the piston rod 28 away from the piston 26, and the inner cavity side wall of the syringe end cover 27 and the outer ring surface of the rear end of the transparent syringe 21 are provided with mutually matching threads, and a handle is also fixed on the rear end of the piston rod 28.

[0032] The connection block 24 has a chamber inside that is connected to the inner cavity of the needle 23, and the top surface of the connection block 24 is provided with a through hole for the guide hose 22 to pass through and fix, wherein the outer ring top surface of the glass support cover 6 is provided with a through hole for the guide hose 22 to pass through. The outer ring surface of the rear section housing 3 is provided with a control button, and the inner cavity of the rear section housing 3 is provided with a power control mainboard, and the rear end surface of the rear section housing 3 is provided with a charging port for charging the dry battery pack 4.

[0033] According to the above-mentioned preferred technical solution, the workflow of the technical solution is described as follows:

[0034] The piston rod 28 and the piston 26 are pulled out from the transparent syringe 21, and the analgesic is injected into the transparent syringe 21. After the piston 26 and the piston rod 28 are inserted back into the transparent syringe 21, the piston rod 28 is pushed to discharge the air inside the transparent syringe 21 from the connecting block 24 and the needle 23. The front end port of the glass support cover 6 is aligned with the area requiring analgesia, and after the control button on the surface of the rear section housing 3 is pressed, the power control mainboard controls the dry battery pack 4 to supply power to the servo motor 51, and the rotating shaft 53 drives the second bevel gear 511 to rotate by driving the first bevel gear 56 to rotate. At the same time, the second bevel gear 511 rotates while revolving around the first bevel gear 56. Since the position of the cylinder 512 deviates from the center of the second bevel gear 511, the cylinder 512 pulls the sleeve 55 forward and backward through the annular groove 54 during the rotation of the second bevel gear 511.

[0035] When the sleeve 55 moves back and forth, it will drive the movable cylinder 58 to move back and forth, and with the help of the movable cylinder 58, it will pull the force transmission cylinder 25 back and forth, thereby forcing the needle 23 at the front end of the force transmission cylinder 25 to penetrate into the patient's body. At this time, the servo motor 51 rotates half a circle and stops, and uses the piston rod 28 and the piston 26 to push the medicine inside the transparent syringe 21 into the patient's body for analgesia. After the injection is completed, the servo motor 51 rotates again to drive the sleeve 55 to move backward, forcing the needle 23 to withdraw from the patient's body.

[0036] The present invention is not limited to the above-mentioned optimal implementation mode. Anyone should be aware that any structural changes made under the inspiration of the present invention, and any technical solutions that are the same or similar to the present invention, fall within the protection scope of the present invention. Finally, it should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the restrictive conditions that can be implemented in this application, so they have no technical substantive significance. Any structural modification, change in proportional relationship or adjustment of size, without affecting the effects that can be produced by this application and the purposes that can be achieved, should still fall within the scope that can be covered by the technical content disclosed in this application.

Claims

1. A microneedle device for local analgesia of neuropathic pain, comprising a middle shell (1), characterized in that: The rear end of the middle shell (1) is fixedly connected to the rear shell (3), the front end of the middle shell (1) is fixedly connected to the glass support cover (6), and a microneedle injection drive mechanism (5) is arranged in the inner cavity of the middle shell (1), a drug injection mechanism (2) penetrating into the interior of the glass support cover (6) is arranged on the top surface of the middle shell (1), and a dry cell battery pack (4) is fixedly connected in the inner cavity of the rear shell (3); The drug injection mechanism (2) comprises a transparent syringe (21), a guide hose (22) fixed to the front end of the transparent syringe (21), and a connection block (24) connected to the end of the guide hose (22) and located inside the glass support cover (6), wherein a needle (23) is screwed and fixed to the front end of the connection block (24), and a force transmission cylinder (25) located in the inner cavity of the middle shell (1) is fixedly connected to the rear end of the connection block (24); wherein a piston (26) is movably arranged inside the transparent syringe (21), and a piston rod (28) penetrating the outside of the transparent syringe (21) is fixedly connected to the rear end of the piston (26); The microneedle injection drive mechanism (5) comprises a servo motor (51), a rotating shaft (53) fixedly connected to the output shaft of the servo motor (51) through a coupling, and a sleeve (55) sleeved on the outer ring of the rotating shaft (53), wherein one end of the rotating shaft (53) away from the servo motor (51) is fixedly connected to a first bevel gear (56), a second bevel gear (511) is meshed on the side of the first bevel gear (56), and a cylinder (512) deviating from the center of the second bevel gear (511) is fixed on the outer surface of the second bevel gear (511), wherein an annular groove (54) is provided on the inner cavity side wall of the sleeve (55), and one end of the cylinder (512) away from the second bevel gear (511) is inserted into the annular groove (54) for coupling.

2. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: The top surface of the servo motor (51) is fixedly connected to the top surface of the inner cavity of the middle section housing (1), and the middle section housing (1) and the rotor of the servo motor (51) are coaxially arranged, wherein a support frame (513) is fixedly connected to the bottom surface of the inner cavity of the middle section housing (1), and a bearing (52) adapted to the rotating shaft (53) is fixed at the top end of the support frame (513).

3. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: A support seat (59) is fixed to the bottom surface of the inner cavity of the middle section housing (1), and a transmission shaft (510) is rotatably connected to the rear side of the support seat (59). The rear end of the transmission shaft (510) passes through the sleeve (55) and is fixedly connected to the front end surface of the first bevel gear (56).

4. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: The left and right end surfaces of the sleeve (55) are respectively provided with circular holes for the transmission shaft (510) and the rotating shaft (53) to pass through, wherein a gap of 1 mm to 3 mm is provided between the outer ring surface of the sleeve (55) and the inner cavity side wall of the middle section housing (1), so that the sleeve (55) can be driven by the second bevel gear (511) to reciprocate forward and backward.

5. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: The front end face of the sleeve (55) is rotatably connected to a movable cylinder (58), and the front end face of the movable cylinder (58) is fixedly connected to the rear end of the force transmission cylinder (25) located in the inner cavity of the middle shell (1), wherein the top surface of the movable cylinder (58) is fixedly connected to a protrusion (57), and the top surface of the inner cavity of the middle shell (1) is provided with a slide groove, the protrusion (57) is inserted into the slide groove for sliding connection, and the bottom surface of the outer ring of the movable cylinder (58) is opened and closed with an opening for the support seat (59) to pass through.

6. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: One end of the cylinder (512) away from the second bevel gear (511) is fixedly connected to a sliding block, and the other end of the sliding block away from the cylinder (512) is located inside the annular sliding groove (54).

7. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: The front end surface of the middle section housing (1) is provided with a through hole for the force transmission cylinder (25) to penetrate and move forward and backward, and the rear end of the glass support cover (6) is fixedly connected to the front end of the middle section housing (1) and covers the connecting block (24) and the needle (23), wherein the length of the glass support cover (6) is longer than the length of the needle (23) by 1 cm to 2 cm.

8. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: The bottom surface of the transparent syringe (21) is fixed to the top surface of the outer ring of the middle shell (1), and the top surface of the outer ring of the transparent syringe (21) is provided with a capacity scale, wherein a syringe end cover (27) is fixed to the outer ring of the end of the piston rod (28) away from the piston (26), and the inner cavity side wall of the syringe end cover (27) and the rear end outer ring surface of the transparent syringe (21) are provided with mutually matching threads, and a handle is also fixed to the rear end of the piston rod (28).

9. A microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: The connection block (24) has a chamber inside that is connected to the inner cavity of the needle (23), and the top surface of the connection block (24) is provided with a through hole for the guide hose (22) to pass through and fix, wherein the top surface of the outer ring of the glass support cover (6) is provided with a through hole for the guide hose (22) to pass through.

10. The microneedle device for local analgesia of neuropathic pain according to claim 1, characterized in that: The outer ring surface of the rear section shell (3) is provided with a control button, and the inner cavity of the rear section shell (3) is provided with a power control mainboard, and the rear end surface of the rear section shell (3) is provided with a charging port for charging the dry battery pack (4).