Pesticidal compositions

Abstract

A pesticidal composition comprising: (i) from 25% to 35% by weight of methoxypiperidine ethyl ester; (ii) from 15% to 25% by weight of cyantraniliprole; and (iii) from 15% to 30% by weight of 4-O-[beta]-D-galactopyranosyl-[alpha]-D-glucopyranose as a filler component.

Description

[0001] The present invention relates to compositions comprising a combination of insecticidal active ingredients, the preparation of such compositions and methods of using such compositions to control pests in crops of useful plants.

[0002] Insecticidal compositions containing a combination of the insecticidal active ingredients spiropidion and cyantraniliprole are known, for example, from WO 2013 / 079564. For practical purposes, such insecticidal compositions are considered to have very favorable activity levels in controlling insect pests in crops of useful plants while also maintaining acceptable crop safety (phytotoxicity) results. Therefore, suitable formulated compositions (e.g., solid particles) containing such insecticidal active ingredient combinations have been sought.

[0003] Among a host of other requirements, it is strongly preferred that agrochemical compositions (in diluted / dispersed form) for spray application do not leave solid residues on the spray application equipment (e.g., nozzles, hoses, tanks, etc.) after use. Such deposits make the cleaning of the spray application equipment more onerous, and the long-term accumulation of such residues may, over time, contaminate future spray applications, or even cause blockages. Likewise, if such dispersions of agrochemical compositions (e.g., water-dispersible granules) are not evenly distributed in the spray tank, or if such characteristics develop over a longer period of time due to poor suspension rate characteristics of the composition, this may result in uneven application of the active ingredient material to the crop field upon application.

[0004] Therefore, there is a great need for compositions that have (i) substantially no residue left in spray application equipment after use, and (ii) good suspension characteristics of solid components and non-volatile ingredients when the composition is dispensed in a spray tank.

[0005] According to the present invention, there is provided a pesticidal composition comprising:

[0006] (i) 25% to 35% by weight of ethyl phenidate;

[0007] (ii) 15% to 25% by weight of cyantraniliprole; and

[0008] (iii) 15 to 30% by weight of 4-O-β-D-galactopyranosyl-α-D-glucopyranose as a filler component.

[0009] Surprisingly, the present invention has found that the use of a certain amount of 4-O-β-D-galactopyranosyl-α-D-glucopyranose as a filler component in a pesticidal composition results in substantially no residue on spray application equipment compared to the use of compositions containing other commonly used fillers. In addition, the pesticidal composition of the present invention has been shown to have beneficial suspension rate properties when diluted for spray application to crops.

[0010] In addition, according to the present invention, there is provided an aqueous composition comprising the pesticidal composition according to the present invention, and optionally further comprising one or more adjuvants or carriers.

[0011] Still further, according to the present invention, there is provided a (non-therapeutic) method of combating and controlling pests, which method comprises applying a composition according to the invention to the pests, to the locus of the pests, or to crops of useful plants susceptible to attack by the pests.

[0012] Methoxypiperidin ethyl ester ([3-(4-chloro-2,6-dimethyl-phenyl)-8-methoxy-1-methyl-2-oxo-1,8-diazaspiro[4.5]dec-3-en-4-yl]ethyl carbonate. CAS number: 1229023-00-0) is known in particular from WO 2010 / 066780, WO 2018 / 114648 and WO 2018 / 114649. Cyantraniliprole (4-bromo-1-(3-chloropyridin-2-yl)-N-[4-cyano-2-methyl-6-(methylcarbamoyl)phenyl]-1H-pyrazole-5-carboxamide. CAS number: 736994-63-1) is known in particular from EP 1 599 463. Certain pesticidal mixtures comprising methylphenidate and cyantraniliprole as active ingredients are known from WO 2013 / 079564.

[0013] Preferably, the composition according to the present invention comprises the following components as pesticidal active ingredients: (i) 28% to 32% by weight of methoxyphenidine ethyl and (ii) 20% to 25% by weight of cyantraniliprole, and more preferably (i) 29% to 31% by weight of methoxyphenidine ethyl and (ii) 21% to 24% by weight of cyantraniliprole. The composition according to the present invention comprises the following components as pesticidal active ingredients: methoxyphenidine ethyl and cyantraniliprole, respectively, in a weight ratio of 1:1 to 7:3, and preferably in a weight ratio of 1:1 to 3:2.

[0014] Preferably, the composition of the present invention comprises 20% to 25% by weight of 4-O-β-D-galactopyranosyl-α-D-glucopyranose as a filler component. 4-O-β-D-galactopyranosyl-α-D-glucopyranose (CAS No. 63-42-3) may also be referred to as 4-O-β-D-galactopyranosyl-α-D-glucose or lactose monohydrate.

[0015] In a preferred embodiment, the composition of the present invention further comprises, based on the total weight of the composition (ie, up to 100% by weight):

[0016] (iv) 10 to 20% by weight of one or more dispersants;

[0017] (v) 1 to 5% by weight of a defoaming agent; and

[0018] (vi) 5 to 10% by weight of a buffer.

[0019] In other preferred embodiments, the composition of the present invention may contain 1 to 3% by weight of an antifoaming agent, and preferably 1.5 to 2.5% by weight of an antifoaming agent.

[0020] When a buffer component is present in the composition of the present invention, it may include an alkali metal sulfate or an alkaline earth metal sulfate, or a combination of an alkali metal sulfate and an alkaline earth metal sulfate. Preferably, the alkali metal sulfate used in the composition of the present invention is potassium sulfate or sodium sulfate, and most preferably sodium sulfate. The buffer may also include an organic acid, such as citric acid.

[0021] Preferably, the composition of the present invention is a water dispersible granule (WG), which can be defined as a solid particulate formulation that can be rapidly dispersed or dissolved when added to water in a spray tank to provide a fine particle suspension containing one or more pesticidal active ingredients. Water dispersible granules containing the composition according to the present invention can be prepared according to standard methods. The water dispersible granules can take the form of extruded granules or spray agglomerated granules.

[0022] Preferably, in the aqueous composition according to the invention (e.g., a tank mix formulation for application to crops), the adjuvant is selected from a mineral oil, a vegetable oil, an esterified vegetable oil, a methylated vegetable oil or an adjuvant based on an alkyl phosphate. Pesticide adjuvants can be defined as substances present in pesticidal compositions (e.g., concentrated active ingredient formulations diluted in water in a tank for foliar spray application to crops) which improve the performance of the pesticidal active ingredient, for example by promoting the spreading of the active ingredient on the leaf surface or penetration into the leaves of the crop plant.

[0023] Examples of adjuvant classes that can be used according to the present invention include mineral oils, vegetable oils, esterified vegetable oils, methylated vegetable oils or alkyl phosphate based adjuvants. Commercially available adjuvant products that can be tank mixed with the composition of the present invention to produce a spray formulation include HASTEN TM (Victorian Chemical Co. Pty. Ltd. - blend of esterified vegetable oil and nonionic surfactant), (Syngenta - Alkyl Phosphate (EC Formulation)), LEDNA TM (Polaquimia - EC formulation containing soybean oil methyl ester), 463 (CRODA Europe Limited - 60% paraffin oil and surfactant blend), B (Bayer AG - rapeseed oil methyl ester (esterified vegetable oil)), HC (Winfield Solutions LLC - Methylated soybean oil), (HELENA - blend of (methylated) vegetable oils and silicone-based nonionic surfactants), and FS Optique TM (GROWMARK Corporation - Canola Methyl Ester).

[0024] Dispersants (dispersant / dispersing agent) are typically surfactant substances that, when added to a suspension of solid particles in a liquid, are able to better separate the particles to prevent them from settling or clumping together. Dispersants that can be used according to the present invention include, but are not limited to, lignin sulfonates (e.g., Ufoxane 3A, Borregard AS; Borresperse NA, Borregard AS; Polyfon TM H, Ingevity; Marasperse CBOS-4 powder, LignoTech), naphthalenesulfonates (e.g., Dispergator B Gran, TFL Ledertechnik GmbH), copolymers of 2,5-furandione and 2,4,4-trimethylpentene (e.g., Ta / 72, Solvay).

[0025] Antifoaming agents are chemical additives that reduce and hinder the formation of foam in compositions such as pesticidal formulations. Antifoaming agents that can be used according to the present invention include, but are not limited to, polydimethylsiloxanes (e.g., XIAMETER TM ACP-1500, Dow, Inc; Antifoam MSA, Univar; Xiameter ACP-0001, Dow Brasil; Xiameter ACP-0100, Dow Chemical).

[0026] In addition to 4-O-β-D-galactopyranosyl-α-D-glucopyranose, small amounts of other conventional fillers may be used according to the present invention. Preferably, the filler component of the composition does not contain diatomaceous earth materials (e.g., Ceilte TM ), or the composition contains less than 10% by weight, or less than 5% by weight, of diatomaceous earth material as a filler.

[0027] Examples of pests that can be controlled by the compositions according to the present invention include those from:

[0028] From the order of the Acarina, for example, Acalitus spp., Aculus spp., Acaricalus spp., Aceria spp., Acarussiro, Amblyomma spp., Argas spp., Boophilus spp., Brevipalpus spp., Bryobia spp., Calipitrimerus spp., Chorioptes spp., Dermanyssus gallinae, Dermatophagoides spp., Eotetranychus spp. spp.), Eriophyes spp., Hemitarsonemus spp., Hyalomma spp., Ixodes spp., Olygonychus spp., Ornithodoros spp., Polyphagotarsone latus, Panonychus spp., Phyllocoptruta oleivora, Phytonemus spp., Polyphagotarsonemus spp., Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp.), Sarcoptes spp., Steneotarsonemus spp., Tarsonemus spp., and Tetranychus spp.;

[0029] From the order of the Licea, for example, Haematopinus spp., Linognathus spp., Pediculus spp., Pemphigus spp. and Phylloxera spp.;

[0030] From the order of the Coleoptera, for example, Agriotes spp., Amphimallon majale, Anomala orientalis, Anthonomus spp., Aphodius spp., Astylus atromaculatus, Ataenius spp., Atomaria linearis, Chaetocnema tibialis, Cerotoma spp., Conoderus spp., Cosmopolites spp., Cotinis nitida, Curculio spp., Cyclocephala spp., Dermestes spp.), Diabrotica spp., Diloboderus abderus, Epilachna spp., Eremnus spp., Heteronychus arator, Hypothenemushampei, Lagria vilosa, Leptinotarsa ​​decemLineata, Lissorhoptrus spp., Liogenys spp., Maecolaspis spp., Maladera castanea, Megascelis spp., Melighetes aeneus, Melolontha spp., Myochrous armatus, Orycaephilus spp., Otiorhynchus spp.), Phyllophaga spp., Phlyctinus spp., Popillia spp., Psylliodes spp., Rhyssomatus aubtilis, Rhizopertha spp., Scarabeidae, Sitophilus spp.), Sitotroga spp., Somaticus spp., Sternechus subsignatus, Tenebrio spp., Tribolium spp., and Trogoderma spp.;

[0031] From the order of the Diptera, for example, Aedes spp., Anopheles spp., Antherigona soccata, Bactrocea oleae, Bibio hortulanus, Bradysia spp., Calliphora erythrocephala, Ceratitis spp., Chrysomyia spp., Culex spp., Cuterebra spp., Dacus spp., Delia spp., Drosophila melanogaster, Fannia spp., Gastrophilus spp., Geomyza tripunctata, Glossina spp., Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza spp., Musca spp., Oestrus spp., Orseolia spp., Oscinella frit, Pegomyia hyoscyami, Phorbia spp., Rhagoletis spp., Rivelia quadrifasciata, Scatella spp., Sciaras spp., Stomoxys spp., Tabanus spp.), tapeworm species (Tanniaspp.), and tipula spp.;

[0032] From the order of the Hemiptera, for example, Acanthocoris scabrator, Acrosternum spp., Adelphocoris lineolatus, Acanthocoris spp., Bathycoeliathalassina, Acanthocoris spp., Acanthocoris spp., Clavigralla tomentosicollis, Creontiades spp., Dichelops furcatus, Edessa spp., Euchistus spp., Eurydema pulchrum, Acrosternum spp., Acanthocoris ... nobilellus), Lygus species, Lygus species, Tropical Scale species, Murgantia histrionic, Nesidiocoris species, Nesidiocoris tenuis, Nysius simulans, Nysius simulans, Nesidiocoris spp. ...

[0033] From the order of the Homoptera, for example, Acyrthosium pisum, Adalges spp., Agalliano ensigera, Targuilon vein psyllid, Aleurodicus spp., Aleurocanthus spp., Sugarcane hole whitefly, Aleurothrixus floccosus, Aleyrodes brassicae, Amarasca biguttula, Citrus leafhopper, Aonidiella auranti, Aphididae, Aphids spp., Aspidiotus spp., Solanum sutchuenensis, Bactericera cockerelli, Aleurodicus spp., Brachycaudus spp. spp.), cabbage aphid, Cavariella species, Cavariella aegopodii Scop., Lecanus species, black brown round shield scale, orange brown round shield scale, leafhopper species, large white leafhopper (Cofana spectra), Cryptozoa species, Leafhopper species, brown soft scale, corn yellow-winged leafhopper, naked whitefly species, citrus psyllid, wheat two-tailed aphid, western round tail aphid species, small green leafhopper species, apple aphid, grape leafhopper species, Gascardia species, red eucalyptus psyllid (Glycaspis brimblecombei), vegetable constriction aphid (Hyadaphis pseudobrassicae), large tail aphid species (Hyalopterus spp.), Hyperomyzus species (Hyperomyzus pallidus), lemon green leafhopper (Idioscopus clypealis), African leafhopper, Laodelphax striatum species, water scale, oyster shield scale species, radish aphid (Lopaphis erysimi), Lyogenys maidis, Macrosiphum species, Fossilidae species, Metcalfa pruinosa, wheat aphid, wheat wax cicada, Tuberculosis species, Neotoxoptera species, Black tail leafhopper species, Nilaparvata spp., pear green aphid, Odonaspis ruthae, sugarcane cotton aphid, bayberry whitefly, Caulis psyllid, Shield scale species, gall aphid species, corn wax cicada, Flathorn planthopper species, Hob wart aphid, Phylloxera spp.), Mosella species, Morus alba species, Mealybug species, Pseudatomoscelis seriatus, Psyllid species, Pulvinaria aethiopica, Quesada gigas, Recilia dorsalis, Aphid species, Black helmet scale species, Leafhopper species, Schizophrenia species, Sitobion spp., White-backed planthopper, Spissistilus festinus, Tarophagus Proserpina, Aphid species, Whitefly species, Tridiscus sporoboli, Trionymus spp., African psyllid, Arrow scale, Flame leafhopper, and Zyginidia scutellaris;.

[0034] From the order of the Hymenoptera, for example Acromyrmex, Arge spp., Atta spp., Cephus spp., Diprion spp., Diprionidae, Gilpinia polytoma, Hoplocampa spp., Lasius spp., Monomorium pharaonis, Neodiprions spp., Pogonomyrmex spp., Fire ants, Solenopsis spp. and Vespa spp.;

[0035] From the order of the Isoptera, for example, Coptotermes spp., Corniternes cumulans, Incisitermes spp., Macrotermes spp., Mastotermes spp., Microtermes spp., Reticulitermes spp.; Tropical fire ant (Solenopsis geminate);

[0036] From the order of the Lepidoptera, for example, Acleris spp., Aegeria spp., Agrotis spp., Alabama argillaceae, Amylois spp., Spodoptera spp., Argyresthia spp., Argyresthia spp., Autographa spp., Cotton miner, Busseola fusca, Cadra cautella, Peach fruit moth, Chilo spp., Leaf rollers, Chrysoteuchia spp. topiaria), grape fruit moth, leaf roller, cloud roller, leaf roller, sheath moth, Pieris, Cosmophila flava, grass borer, Crocidolomia binotalis, apple roller, box moth, leaf roller, box moth, Diatraea spp., Sudan bollworm, Diparopsis castanea, diamond borer, African stem borer, mealybug, Epinotia spp., Etiella zinckinella, flower roller, ring moth, yellow tussock moth, root cutter, Feltia jaculiferia, Grapholita spp., green budworm, Heliothis spp.), cabbage borer, Herpetogramma spp.), American white moth, tomato borer, Lasmopalpus lignosellus, spiral leafminer, leafminer species, grape flower moth, Loxostege bifidalis, tussock moth species, miner species, leafworm species, Mamestra brassicae, tobacco hornworm, Mythimna species, Noctua species, fall geometrid species, Orniodes indica, European corn borer, super-small tortoise species, brown tortoise species, small-eyed moth, stem borer, red bell moth, coffee leafminer, one-star armyworm, potato moth (Phthorimaea operculella), cabbage butterfly, Pieris species, diamondback moth (Plutella xylostella), bud moth species, leaf moth species, mint budworm, Richia albicosta, Scirpophaga species (Scirpophaga spp.), Sesamia spp., Spodoptera spp., Cotton leaf folder, Xenopus spp., Heteroptera spp., Tortrix spp., Cabbage looper, Tomato leafminer, and Lymantria spp.;

[0037] From the order Trichophagus, for example, species of the genus Trichodes and species of the genus Trichodes;

[0038] From the order of the Orthoptera, for example, Blatta, Blattella, Gryllotalpa, Madeira Blattella, Locusta, Neocurtillahexadactyla, Periplaneta, Scapteriscus spp, and Locusta;

[0039] From the order of the order of the Pseudoptera, for example, Liposcelis spp.;

[0040] From the order of the Siphonaptera, for example, Ceratophyllus spp., Ctenocephalides spp. and Xenopsylla cheopis;

[0041] From the order of the Thysanoptera, for example, Calliothrips phaseoli, Frankliniella spp., Heliothrips spp., Hercinothrips spp., Parthenothrips spp., Scirtothrips aurantii, Sericothrips variabilis, Taeniothrips spp., Thrips spp.; and / or

[0042] From the order of the Thysanura, for example, the Silverfish (Lepisma saccharina).

[0043] Examples of soil-dwelling pests that may damage crops at an early stage of plant development are:

[0044] From the order of the Lepidoptera, for example, species of the genus Tortoise, species of the genus Transparentwing, species of the genus Spodoptera, species of the genus Cotton leafworm, species of the genus Starchworm, species of the genus Spodoptera, species of the genus Corn armyworm, species of the genus Cabbage moth, species of the genus Sesamia, species of the genus Graminus, species of the genus Cabbage moth, species of the genus Plutella xylostella, species of the genus Grain borer, species of the genus Spodoptera, species of the genus Spodoptera and species of the genus Leafroller;

[0045] From the order of the Coleoptera, for example, species of the genera Conotrachelus, species of the genera Flora, species of the genera Cryptophaga, species of the genera Conotrachelus, species of the genera Root-necked Desmodium, species of the genera Curculionidae, species of the genera Dermestidae, species of the genera Dilopoderus, species of the genera Phytophagous, species of the genera Eremnus, species of the genera Heteronychus, species of the genera Rhinoceros, species of the genera Phytophagous, species of the genera Saw-beaked Millet, species of the genera Echinops, species of the genera Phytophagous, species of the genera Phytophagous, species of the genera Flea Beetle, species of the genera Scarabidae, species of the genera Phytophagous, species of the genera Pseudo-cutting worm, species of the genera Tanymecus, species of the genera Pseudofloxacin, species of the genera Pseudofloxacin, species of the genera Trogoderma, and species of the genera Zabrus;

[0046] From the order Orthoptera, such as species of the genus Gryllotalpa;

[0047] from the order Isoptera, such as species of the genus Reticulitermes;

[0048] From the order of the order Pseudostellaria, such as species of the genus Pseudostellaria;

[0049] From the order of the Licea, for example, Haematophis species, Macrognathus species, Pediculus species, Aphis species and Phylloxera species;

[0050] from the order Homoptera, such as the cotton apple aphid;

[0051] from the order Hymenoptera, such as Myrmecophaga, Myrmecophaga species, Myrmecophaga species, Myrmecophaga species, Myrmecophaga species, Myrmecophaga species, Myrmecophaga species, Myrmecophaga species, and Vespa species;

[0052] from the order Diptera, such as species of the genus Crane;

[0053] Cruciferae flea beetles (Phyllotreta spp.), root maggots (Phyllophora spp.), cabbage weevils (Ceutorhynchus spp.), and aphids.

[0054] In particular, the compositions of the invention can be applied against insects from the orders Homoptera (especially whiteflies, aphids, psyllids and armored and soft scales), Thysanoptera (thrips), Acarina (mites) and Lepidoptera (butterflies and moths, and their larvae). Preferably, the composition of the invention can be applied against whiteflies, aphids, thrips, in particular silverleaf whitefly (Bemisia tabaci), greenhouse whitefly (Trialeurodes vaporariorum), western flower thrips (Frankliniella occidentalis), onion thrips (Thrips tabaci), tomato thrips (Frankliniella schultzei), leafhoppers, melon thrips (Thrips palmi), tuft caterpillars (Spodoptera litura) and potato tuber moth (Phthorimaea operculella).

[0055] Crops of useful plants in which the compositions according to the invention can be used include perennial and annual crops, such as berry plants, for example blackberries, blueberries, cranberries, raspberries and strawberries; cereals, for example barley, maize (corn), millet, oats, rice, rye, sorghum, triticale and wheat; fiber plants, for example cotton, flax, hemp, jute and sisal; field crops, for example sugar and fodder beets, coffee beans, hops, mustard, rapeseed (canola), poppy, sugar cane, sunflower, tea and tobacco; fruit trees, for example apples, apricots, avocados, bananas, cherries, citrus, nectarines, peaches, pears and plums; grasses, for example Bermuda grass, bluegrass, bentgrass, centipede grass, fescue, ryegrass, St. Augustine's sedge, sedge grass ... The compositions of the present invention can also be applied to turf, lawns and pastures.

[0056] Preferably, the composition according to the invention can be applied to crops of useful plants selected from the group consisting of:

[0057] - Solanales (including tomatoes, potatoes, eggplants, capsicums, peppers, tobacco);

[0058] - Cucurbitales (including pumpkins, squash, watermelons, melons, cucumbers);

[0059] - Alliums (including onions, garlic, leeks);

[0060] - Asparagaceae (including asparagus)

[0061] - Cruciferous vegetables (including broccoli, cauliflower, cabbage).

[0062] Preferably, the composition according to the invention can be applied to crops of useful plants selected from the group consisting of cotton, cucumber, tomato, pepper, capsicum, broccoli, cauliflower, cabbage.

[0063] In some embodiments of the methods of the invention, the composition is applied to the soil (or other growth medium) of a crop of useful plants by dripping, drenching or injecting.

[0064] The application rate of the agrochemical composition of the present invention will depend on the specific type of insects to be controlled, the degree of control required, and the time arrangement and method of application and can be easily determined by those skilled in the art. Generally, the composition of the present invention can be applied at an application rate between 0.005 kilograms per hectare (kg / ha) and about 5.0 kg / ha based on the total amount of active ingredients in the composition. An application rate between about 0.1 kg / ha and about 1.5 kg / ha is preferred, with an application rate between about 0.3 g / ha and 0.8 kg / ha being particularly preferred.

[0065] The pesticidal compositions of the present invention can be used as insecticides to control pests on cotton plants, particularly for controlling insects from the orders Homoptera (particularly whiteflies, aphids, psyllids, Lepidoptera and armored soft scales), Thysanoptera (thrips) and Acarina (mites).

[0066] The pesticidal compositions of the present invention can be used as insecticides to control pests on cotton plants, particularly for controlling insects from the orders Homoptera (particularly whiteflies, aphids, psyllids, Lepidoptera and armored soft scales), Thysanoptera (thrips) and Acarina (mites).

[0067] In particular, transgenic cotton events expressing useful traits that can be used in combination with the compositions of the present invention include BXN10211, BXN10215, BXN10222, BXN10224, COT102, COT67B, GHB614, GHB119, LLCotton25, MON531, MON757, MON15985, MON1445, MON88913, MON1076, MON1698, MON88701, T304-40, 281-24-236, 3006-210-23, 31707, 31803, 31808, 42317, etc. Such combinations of the compositions of the present invention with cotton events expressing one or more useful traits can provide more durable yield protection, provide resistance management strategies for target pest control, and reduce farmer inputs, saving huge expenses in time and monetary value.

[0068] In an aqueous composition (e.g. a tank mix composition) comprising the pesticidal composition according to the present invention, an additional component comprising a pesticidal active ingredient selected from one or more of the following may be added:

[0069] Abamectin, Acequinocyl, Acetamiprid, Acetoprole, Acrinathrin, Acynonapyr, Afidopyropen, Afoxalaner, Alanycarb, Allethrin, Alpha-Cypermethrin, Alphamethrin, Amidoflumet, Amino carb), Azocyclotin, Bensultap, Benzoximate, Benzpyrimoxan, Betacyfluthrin, Beta-cypermethrin, Bifenazate, Bifenthrin, Binapacryl, Bioallethrin, Bioallethrin (S)-cyclopentyl isomer, Bioresmethrin, Bistrif luron), Broflanilide, Brofluthrinate, Bromophos-ethyl, Buprofezine, Butocarboxim, Cadusafos, Carbaryl, Carbosulfan, Cartap, CAS No.: 1472050-04-6, CAS No.: 1632218-00-8, CAS No.: 1808115-49-2, CAS No.: 2032403-97-5, CAS No.: 20 44701-44-0, CAS No.: 2128706-05-6, CAS No.: 2249718-27-0, Chlorantraniliprole, Chlordane, Chlorfenapyr, Chloroprallethrin, Chromafenozide, Clenpirin, Cloethocarb, Clothianidin, 2-Chlorophenyl N-methylcarbamate (CPMC), Cyanofenphos,Cyclaniliprole, Cyclobutrifluram, Cycloprothrin, Cycloxaprid, Cycloxaprid, Cyenopyrafen, Cyetpyrafen or Etpyrafen, Cyflumetofen, Cyfluthrin, Cyhalodiamide, Cyhalothrin, Cypermethrin, Benzene Cyphenothrin, Cyproflanilide, Cyromazine, Deltamethrin, Diafenthiuron, Dialifos, Dibrom, Dicloromezotiaz, Diflovidazine, Diflubenzuron, Dimpropyridaz, Dinactin, Dinocap, Dinotefuran ), Dioxabenzofos, Emamectin, Empenthrin, Epsilon-momfluorothrin, Epsilon-metofluthrin, Esfenvalerate, Ethion, Ethiprole, Etofenprox, Etoxazole, Famphur, Fenazaquin, Fenfluthrin, Fenitrothion, Fenobucarb, Fenothiocarb, Fenoxycarb, Fenpropathrin, Fenpyroxymate, Fensulfothion, Fenthion, Fentinacetate, Fenvalerate, Fipronil, Flometoquin, Flonicamid, Fluacrypyrim,Fluazaindolizine, Fluazuron, Flubendiamide, Flubenzimine, Flucitrinate, Flucycloxuron, Flucythrinate, Fluensulfone, Flufenerim, Flufenprox, Flufiprole, Fluhe xafon), Flumethrin, Fluopyram, Flupyradifurone, Flupyrimin, Fluralaner, Flupentiofenox, Fluvalinate, Fluxametamide, Fosthiazate, Gamma-Cyhalothrin, Gossyplure, TM, Guadipyr, Halofenozide, Halofenozide, Halofenprox, Heptafluthrin, Hexythiazox, Hydramethylnon, Imicyafos, Imidacloprid, Imiprothrin, Indoxacarb, Iodometha ne), Iprodione, Isocycloseram, Isothioate, Ivermectin, Kappa-bifenthrin, Kappa-tefluthrin, Lambda-Cyhalothrin, Lepimectin, Lufenuron, Metaflumizone, Metaldehyde aldehyde), Metam, Methomyl, Methoxyfenozide, Metofluthrin, Metolcarb, Mexacarbate, Milbemectin, Momfluorothrin, Nicofluprole, Niclosamide, Nitenpyram, Nithiazine, Omethoate, Oxamyl, Oxazosulfyl, Parathion-ethyl, Permethrin, Phenothrin, Phosphocarb, Piperonylbutoxide, Pirimicarb, Pirimiphos-ethyl, Polyhedrosis virus virus), Prallethrin, Profenofos, Profenofos, Profluthrin, Propargite, Propetamphos, Propoxur, Prothiophos,Protrifenbute, Pyflubumide, Pymetrozine, Pyraclofos, Pyrafluprole, Pyridaben, Pyridalyl, Pyrifluquinazon, Pyrimidifen, Pyrimostrobin, Pyriprole, Pyriproxyfen, Resmethrin, Sarolane r), Selamectin, Silafluofen, Spinetoram, Spinosad, Spirodiclofen, Spiromesifen, Spirotetramat, Sulfoxaflor, Tebufenozide, Tebufenpyrad, Tebupirimiphos, Tefluthrin, Temephos, Teclofenamide trachloraniliprole), Tetradiphon, Tetramethrin, Tetramethylfluthrin, Tetranactin, Tetraniliprole, Theta-cypermethrin, Thiacloprid, Thiamethoxam, Thiocyclam, Thiodicarb, Thiofanox, Thiomethylthioate meton), Thiosultap, Tioxazafen, Tolfenpyrad, Toxaphene, Tralomethrin, Transfluthrin, Triazamate, Triazophos, Trichlorfon, Trichloronate, Trichlorphon, Triflumezopyrim, Tyclopyrazoflor,Zeta-Cypermethrin.

[0070] As already indicated, for practical purposes, the pesticidal compositions of the present invention have very favorable activity levels in controlling insect pests in crops of useful plants after foliar or soil application, while also maintaining acceptable crop safety (phytotoxicity) results. In addition, the compositions of the present invention may have many other benefits when in agrochemical formulations compared to other compositions, including, among others, prevention of precipitation, thickening, phase separation, clouding, foaming or crystal growth, chemical stability (degradation) of the active ingredients, long-term formulation stability (e.g., at elevated temperatures such as 45° C.), and spray drift.

[0071] Figure 1 The sieve (300 μm and 150 μm) residues of the discharge of Composition A and Composition B as described according to the method outlined in Residue Study (i) below are shown.

[0072] Examples :

[0073] The following examples serve to illustrate the invention and in particular demonstrate the surprising effect of using a specific amount of 4-O-β-D-galactopyranosyl-α-D-glucopyranose in the composition according to the invention in:

[0074] (i) minimizing the deposition of solid residues on surfaces such as nozzle filters, spray tanks (including knapsack sprayers), etc., used in applying the pesticidal composition to crops; and

[0075] (ii) Improving the suspension rate of a water dispersible granular composition once dispersed in a large volume of water for application to crops.

[0076] 4-O-β-D-galactopyranosyl-α-D-glucopyranose (CAS No. 63-42-3), also known as (+)-lactose, is commercially available, for example as PHARMATOSE 200M (DFE Pharma International, Germany). Celite TM 209 (CAS No. 61790-53-2) is commercially available from various sources, such as Celite France.

[0077] Referring to Table 1 below, composition A is a composition not according to the present invention as a water-dispersible granule (comprising Celite TM (diatomaceous earth) filler), and composition B is a composition according to the present invention as a water-dispersible granule (without Celite TMFiller). Composition A and composition B are substantially the same in other aspects, except that Celite TM 209 for the price of containing additional lactose filler.

[0078] The composition according to the invention (composition B) and the composition as comparative example (composition A) were prepared according to known formulation methods for water-dispersible (wettable) granules using a basket extruder with a diameter of 0.6 mm.

[0079] Table 1:

[0080]

[0081] (i) Residue studies

[0082] A backpack spray test was performed using a Cooper Pegler 3 backpack sprayer on composition A and composition B (80 g of product in 20 L) to evaluate the performance in terms of residue formation at spray completion and cleaning. In a separate experiment, the sprayer tank was half filled with water (10 L), then composition A or B (80 g) was added to the tank, which was gently agitated to disperse the granular composition. Before starting the spray application, the tank was filled (20 L) and the contents were further agitated. At the end of the spray process, when the tank was emptied, the discharge (water used for rinsing and cleaning the backpack device) was visually evaluated.

[0083] In particular, the effluent was filtered through 150 μm and 300 μm sieves (see Figure 1 ). For composition A, if from Figure 1 It can be clearly seen that some white solid residue was observed, which was not evident (or at a very low level) in the discharge of the test using composition B. It should be noted that the Celite TM The material has an average particle size in the range of about 10 μm to 15 μm, significantly smaller than the mesh diameter.

[0084] These enhanced spray application characteristics of the compositions according to the present invention result in almost no residue, which is considered unusual for extruded water-dispersible granules. A possible explanation for this observation may be that the formation of residue is due to the Celite TM The 209 component absorbs some of the dispersant / surfactant component of the composition.

[0085] (ii) Suspension rate study

[0086] In this example, the suspension rate of composition A and composition B is defined as the percentage of solid particles and non-volatile components remaining in the suspension after standing in a cylindrical column of water (250 mL) at 30° C. for a defined period of time (initial suspension rate analysis). In this example, the water-dispersible particles of composition A and composition B were tested at a dilution of 1% w / v in water.

[0087] At the end of the 30 minute rest period, the top 9 / 10 (225 mL) of the test sample volume was removed, avoiding turbulence and discarded. The remaining 1 / 10 (25 mL) was retained and the suspension rate was determined by conventional gravimetric analysis by evaporating the water from the sample, weighing the dried sample, and then calculating the suspension rate percentage based on the observed weight relative to the expected weight for the optimal suspension rate (i.e., 10% of the original weight of Composition A and Composition B). Tests were also conducted according to this procedure in which the suspensions were left at 54°C for 2 weeks and at 40°C for 8 weeks.

[0088] The higher the suspension percentage (see Table 2), the better the composition performs in terms of uniform distribution of solid particles and non-volatile ingredients throughout the volume of the sample (ie, 100% = best suspension. 0% = settled and no suspended / completely settled contents).

[0089] Table 2:

[0090] Composition At temperature (℃) after time (weeks) Suspension rate (%) A initial 59 A 2 weeks at 54°C 57 A 8 weeks at 40°C 58 B initial 95 B 2 weeks at 54°C 96 B 8 weeks at 40°C 96

[0091] It is clear from the suspension rate data in Table 2 that composition B according to the present invention has far superior suspension rate characteristics to composition A.

Claims

1. A pesticidal composition comprising: (i) 25% to 35% by weight of ethyl phenidate; (ii) 15% to 25% by weight of cyantraniliprole; and (iii) 15 to 30% by weight of 4-O-β-D-galactopyranosyl-α-D-glucopyranose as a filler component.

2. The pesticidal composition according to claim 1, comprising: (i) 28% to 32% by weight of ethyl phenidate; and (ii) 20% to 25% by weight of cyantraniliprole.

3. The pesticidal composition according to claim 1 or claim 2, comprising: (iii) 20 to 25% by weight of 4-O-β-D-galactopyranosyl-α-D-glucopyranose.

4. The pesticidal composition according to any one of claims 1 to 3, wherein The filler component comprises less than 5% by weight of a diatomaceous earth material (e.g., Celite TM ), or does not contain diatomaceous earth material.

5. The pesticidal composition according to any one of claims 1 to 4, further comprising: (iv) 10 to 20% by weight of one or more dispersants; (v) 1 to 5% by weight of a defoaming agent; and (vi) 5 to 10% by weight of a buffer.

6. The composition according to any one of claims 1 to 5, further comprising: one or more additional ingredients selected from wetting agents, biocides, stabilizers and pigments.

7. The pesticidal composition according to any one of claims 1 to 6, further comprising: an additional insecticidal active ingredient.

8. The pesticidal composition according to any one of claims 1 to 7, which is a water-dispersible granule.

9. An aqueous composition comprising the pesticidal composition according to any one of claims 1 to 8, optionally further comprising one or more adjuvants or carriers.

10. The aqueous composition according to claim 9, wherein The adjuvant is selected from mineral oil, vegetable oil, esterified vegetable oil, methylated vegetable oil or an adjuvant based on alkyl phosphate.

11. A method for combating and controlling pests, which method comprises applying a composition according to any one of claims 1 to 10 to the pests, to the locus of the pests, or to crops of useful plants susceptible to attack by the pests.

12. The method according to claim 11, wherein: The pest is selected from the order Homoptera, Thysanoptera, Acarina or Lepidoptera.

13. The method according to claim 12, wherein: The harmful organisms are selected from whiteflies, aphids and thrips.

14. The method according to any one of claims 11 to 13, wherein: The plant is selected from: (i) cotton; or (ii) fruits and vegetables, especially those of the genus Cucurbita, the family Cruciferae or the family Solanaceae, And preferably, the plant is selected from cotton, cucumber, tomato, pepper, chili, broccoli, cauliflower, cabbage.

15. The method according to any one of claims 11 to 14, wherein: The composition is applied to the soil of the crop of useful plants by dripping, drenching or injection.

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