Wall-attached thrombus evaluation device, method and equipment and readable storage medium

Abstract

The invention discloses a wall-attached thrombus evaluation device, method and equipment and a readable storage medium, which are applied to the technical field of computers, and the device comprises the following steps: a section extraction module determines a plurality of sections according to the size of a tumor in a target part image; the section comprises a blood vessel wall boundary, a flow cavity boundary, a wall-attached thrombus and a flow cavity structure; the measurement module measures the maximum diameter and the minimum diameter of the flow cavity in the target section and the maximum diameter and the minimum diameter of the blood vessel wall to obtain a measurement result; the equivalent diameter calculation module calculates the equivalent flow cavity diameter and the equivalent blood vessel wall diameter of the target section based on the measurement result; the flow cavity reserve coefficient calculation module calculates the flow cavity reserve coefficient based on the equivalent flow cavity diameter and the equivalent blood vessel wall diameter of the multiple sections; and the evaluation module determines the severity level of the wall-attached thrombus through the flow cavity reserve coefficient. The device can accurately evaluate the severity level of the wall-attached thrombus, the clinical diagnosis and treatment management of the aneurysm is more comprehensive and accurate, and the risk of aneurysm rupture is reduced.

Description

Technical Field

[0001] The present invention relates to the field of computer technology, and in particular to a mural thrombus assessment device, method, equipment and readable storage medium. Background Art

[0002] Currently, the clinical diagnosis and treatment management of aneurysms mainly rely on the maximum diameter of the aneurysm and its annual growth rate as key reference indicators. These parameters are regularly monitored to assess the patient's risk of disease progression and formulate corresponding treatment strategies accordingly.

[0003] Through research, it was found that the intraluminal thrombus (ILT) growing inside the aneurysm has a significant impact on the rupture of the aneurysm. Therefore, the quantitative evaluation of the intraluminal thrombus also has clinical significance and clinical value. Summary of the invention

[0004] In view of this, an object of the present invention is to provide a mural thrombus assessment device, method, apparatus and readable storage medium, which solve the problem of inaccurate aneurysm status detection in the prior art.

[0005] In order to solve the above technical problems, the present invention provides a mural thrombus assessment device, comprising:

[0006] A section extraction module is used to determine multiple sections according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the cavity boundary, the mural thrombus and the cavity structure;

[0007] A measuring module, used for measuring the maximum diameter and minimum diameter of the lumen in the target section, and the maximum diameter and minimum diameter of the blood vessel wall, to obtain a measurement result; the measurement result includes the maximum diameter of the lumen, the minimum diameter of the lumen, the maximum diameter of the blood vessel wall, and the minimum diameter of the blood vessel wall; the target section is any one of the multiple sections;

[0008] An equivalent diameter calculation module, used for calculating the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement results;

[0009] A lumen reserve coefficient calculation module, used for calculating the lumen reserve coefficient based on the equivalent lumen diameter and equivalent blood vessel wall diameter of multiple sections;

[0010] An evaluation module is used to determine the severity level of the mural thrombus according to the flow cavity reserve coefficient.

[0011] Optionally, the equivalent diameter calculation module includes:

[0012] The equivalent flow cavity diameter calculation unit is used to calculate the equivalent flow cavity diameter according to Calculate and obtain the equivalent flow cavity diameter;

[0013] Equivalent vessel wall diameter calculation unit, used to calculate the equivalent vessel wall diameter according to Calculating and obtaining the equivalent blood vessel wall diameter;

[0014] in, It represents the equivalent flow cavity diameter; Indicates the maximum diameter of the flow cavity; Indicates the minimum diameter of the flow cavity; represents the equivalent vessel wall diameter; Indicates the maximum diameter of the blood vessel wall; Indicates the minimum diameter of the blood vessel wall.

[0015] Optionally, the flow cavity reserve coefficient calculation module includes:

[0016] The flow cavity reserve coefficient calculation unit is used to calculate the Calculating and obtaining the flow cavity reserve coefficient;

[0017] in, represents the flow cavity reserve coefficient; Indicates the total number of slices; represents the equivalent flow cavity diameter of the nth section; Represents the equivalent vessel wall diameter of the nth section.

[0018] Optionally, assessment modules including:

[0019] A first result unit, used for determining that the severity level of the mural thrombus is low mural thrombus when the lumen reserve coefficient is less than a first preset threshold value;

[0020] A second result unit is used for determining that the severity level of the mural thrombus is moderate mural thrombus when the lumen reserve coefficient is greater than the first preset threshold value and less than the second preset threshold value;

[0021] The third result unit is used for indicating that when the lumen reserve coefficient is greater than the second preset threshold, the severity level of the mural thrombus is high mural thrombus; wherein the first preset threshold is less than the second preset threshold.

[0022] Optionally, it also includes:

[0023] A first data sending module, used for sending the lumen reserve coefficient and the severity level of the mural thrombus to a memory for storage;

[0024] The second data display module is used to send the lumen reserve coefficient and the severity level of the mural thrombus to a display for display.

[0025] The present invention also provides a mural thrombus assessment method, which is applied to a processor and includes:

[0026] Determine multiple sections according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the cavity boundary, the mural thrombus and the cavity structure;

[0027] The maximum diameter and the minimum diameter of the lumen in the target section, as well as the maximum diameter and the minimum diameter of the blood vessel wall are measured to obtain measurement results; the measurement results include the maximum diameter of the lumen, the minimum diameter of the lumen, the maximum diameter of the blood vessel wall, and the minimum diameter of the blood vessel wall; the target section is any one of the multiple sections;

[0028] Calculate the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement results;

[0029] Calculate the lumen reserve coefficient based on the equivalent lumen diameter and the equivalent blood vessel wall diameter of multiple sections;

[0030] The severity of the mural thrombus is determined by the flow reserve coefficient.

[0031] Optionally, calculating the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement result includes:

[0032] according to Calculate and obtain the equivalent flow cavity diameter;

[0033] according to Calculating and obtaining the equivalent blood vessel wall diameter;

[0034] in, It represents the equivalent flow cavity diameter; Indicates the maximum diameter of the flow cavity; Indicates the minimum diameter of the flow cavity; represents the equivalent vessel wall diameter; Indicates the maximum diameter of the blood vessel wall; Indicates the minimum diameter of the blood vessel wall.

[0035] Optionally, determining the severity of the mural thrombus by the lumen reserve coefficient includes:

[0036] When the lumen reserve coefficient is less than the first preset threshold, the severity level of the mural thrombus is low mural thrombus;

[0037] When the lumen reserve coefficient is greater than the first preset threshold value and less than the second preset threshold value, the severity level of the mural thrombus is moderate mural thrombus;

[0038] When the lumen reserve coefficient is greater than the second preset threshold, the severity level of the mural thrombus is high mural thrombus; wherein the first preset threshold is less than the second preset threshold.

[0039] The present invention also provides a mural thrombus assessment device, comprising:

[0040] Memory for storing computer programs;

[0041] A processor is used to implement the mural thrombus assessment method as described above when executing the computer program.

[0042] The present invention also provides a computer-readable storage medium, wherein the computer-readable storage medium stores computer-executable instructions, and when the computer-executable instructions are loaded and executed by a processor, the mural thrombus assessment method as described above is implemented.

[0043] It can be seen that the present invention provides a mural thrombus assessment device, which includes a section extraction module, a measurement module, an equivalent diameter calculation module, a cavity reserve coefficient calculation module and an assessment module. The section extraction module is used to determine multiple sections according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the cavity boundary, the mural thrombus and the cavity structure; the measurement module is used to measure the maximum diameter and the minimum diameter of the cavity in the target section, and the maximum diameter and the minimum diameter of the vascular wall to obtain measurement results; the measurement results include the maximum cavity diameter, the minimum cavity diameter, the maximum vascular wall diameter and the minimum vascular wall diameter; the target section is any one of the multiple sections; the equivalent diameter calculation module is used to calculate the equivalent cavity diameter and the equivalent vascular wall diameter of the target section based on the measurement results; the cavity reserve coefficient calculation module is used to calculate the cavity reserve coefficient based on the equivalent cavity diameter and the equivalent vascular wall diameter of multiple sections; the assessment module is used to determine the severity level of the mural thrombus through the cavity reserve coefficient. The flow cavity reserve coefficient FLR proposed in the present invention does not require complex and time-consuming operations such as model annotation and volume calculation and analysis. The analysis can be completed simply and efficiently with the help of commonly used measurement tools in clinical practice. At the same time, the FLR parameter can effectively reflect the severity of mural thrombus in aneurysms, providing an additional basis for the clinical diagnosis and management of aortic aneurysms. Furthermore, on the basis of the existing maximum aneurysm diameter and its growth rate parameters, the quantitative assessment of mural thrombus provided by the present invention is used to supplement the personalized assessment index of aneurysm risk, which is helpful for comprehensive and accurate clinical diagnosis and management of aneurysms and reduces the risk of aneurysm rupture; and the device has a simple calculation method and high analysis efficiency, which is convenient for clinical acquisition and use.

[0044] In addition, the present invention also provides a mural thrombus assessment method, device and readable storage medium, which also have the above-mentioned beneficial effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0045] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.

[0046] Figure 1 A flowchart of a mural thrombus assessment method provided by an embodiment of the present invention;

[0047] Figure 2 A schematic diagram of a sectioning method provided by an embodiment of the present invention;

[0048] Figure 3 A cross-sectional schematic diagram provided for an embodiment of the present invention;

[0049] Figure 4 A boundary image map provided by an embodiment of the present invention;

[0050] Figure 5 A schematic diagram of a flow cavity diameter measurement result provided by an embodiment of the present invention;

[0051] Figure 6 A schematic diagram of a blood vessel wall diameter measurement result provided by an embodiment of the present invention;

[0052] Figure 7 A schematic structural diagram of a mural thrombus assessment device provided by an embodiment of the present invention;

[0053] Figure 8 A schematic structural diagram of a mural thrombus assessment device provided in an embodiment of the present invention. DETAILED DESCRIPTION

[0054] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0055] The intraluminal thrombus (ILT) growing inside the aneurysm has a significant impact on the rupture of the aneurysm. The growth of the mural thrombus may indicate an increased risk of rupture. Therefore, when the thrombosis factor is incorporated into the aneurysm rupture risk prediction model, the accuracy of the prediction can be increased. Therefore, in the clinical diagnosis and treatment of aneurysms, the quantitative evaluation results of the mural thrombus can be used as a supplementary parameter to the maximum diameter and growth rate, which has clinical significance and value for the assessment of the risk of aneurysm rupture. The present invention provides a quantitative evaluation method for mural thrombus, please refer to Figure 1 , Figure 1 A flowchart of a mural thrombus assessment method provided by an embodiment of the present invention. The method may include:

[0056] S101: Determine multiple sections according to the size of the tumor in the target area image; the sections include the vascular wall boundary, the lumen boundary, the mural thrombus and the lumen structure.

[0057] The executor of this embodiment is a processor. This embodiment does not limit the type of processor, as long as it can complete the operation of the mural thrombus assessment method. The target part in this embodiment refers to the tumor. This embodiment does not limit the image of the target part, as long as it is an image containing the tumor. This embodiment does not limit the method of obtaining the target part image. For example, it can be an image obtained by medical imaging methods such as CTA (Computed Tomography Angiography) or MR (Magnetic Resonance Imaging). The tumor in this embodiment refers to an aneurysm, or it can be an aortic aneurysm.

[0058] When the processor receives the target part image, it can process the tumor and obtain multiple sections, such as Figure 2 Specifically, according to the length of the tumor along the centerline, several sections perpendicular to the centerline are taken in the axial centerline direction. The section diagram can be referred to Figure 3 , Figure 3 A cross-sectional schematic diagram provided by an embodiment of the present invention, comprising Figure 3 It can be seen that the section includes the vascular wall boundary, lumen boundary, mural thrombus and lumen structure.

[0059] S102: Measure the maximum diameter and minimum diameter of the lumen in the target section, and the maximum diameter and minimum diameter of the blood vessel wall to obtain measurement results; the measurement results include the maximum diameter of the lumen, the minimum diameter of the lumen, the maximum diameter of the blood vessel wall, and the minimum diameter of the blood vessel wall; the target section is any one of the multiple sections.

[0060] Multiple sections are obtained through step S101, and the measurement process is described by taking one of the sections as an example. Specifically, the cavity boundary and the vascular wall boundary can be detected by the edge detection method. This embodiment does not limit the edge detection method. For example, Sobel operator, Canny operator, etc. can be used. The cavity and the vascular wall can be obtained according to the cavity boundary and the vascular wall boundary, and the cavity and the vascular wall are further measured. Since the cavity and the vascular wall are not conventional shapes, they can be measured by the diameter method, such as measuring their maximum diameter and minimum diameter, so as to obtain the maximum diameter of the cavity, the minimum diameter of the cavity, the maximum diameter of the vascular wall, and the minimum diameter of the vascular wall. Of course, the area of ​​the cavity and the area of ​​the vascular wall can also be calculated, but this method puts higher requirements on the image processing algorithm. Therefore, this method based on the diameter method can reduce the algorithm requirements and improve the processing speed of the processor.

[0061] This method can use medical measurement software to measure the cavity and blood vessel wall, such as Figure 4 , Figure 5 and Figure 6 As shown, Figure 4 A boundary image map provided by an embodiment of the present invention; Figure 5 A schematic diagram of a flow cavity diameter measurement result provided by an embodiment of the present invention, Figure 6 A schematic diagram of a blood vessel wall diameter measurement result provided by an embodiment of the present invention.

[0062] S103: Calculate the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement results.

[0063] In this embodiment, based on the above-mentioned maximum lumen diameter, minimum lumen diameter, maximum vascular wall diameter, and minimum vascular wall diameter, the equivalent lumen diameter and equivalent vascular wall diameter (lumen + mural thrombus) of each section can be calculated. Specifically, the equivalent lumen diameter and equivalent vascular wall diameter can be calculated with reference to the following formula:

[0064] according to The equivalent flow cavity diameter is calculated;

[0065] according to The equivalent vessel wall diameter was calculated;

[0066] in, It represents the equivalent flow cavity diameter; Indicates the maximum diameter of the flow cavity; Indicates the minimum diameter of the flow cavity; represents the equivalent vessel wall diameter; Indicates the maximum diameter of the blood vessel wall; Indicates the minimum diameter of the blood vessel wall.

[0067] S104: Calculate the lumen reserve coefficient based on the equivalent lumen diameter and the equivalent blood vessel wall diameter of multiple sections.

[0068] By measuring the cavity and the blood vessel wall in step S102 and step S103, the equivalent cavity diameter and the equivalent blood vessel wall diameter of multiple tangent lines can be obtained. Equivalent vessel wall diameter Calculate the cavity reserve coefficient The specific calculation formula can be referred to as follows:

[0069] according to The flow cavity reserve coefficient was calculated;

[0070] in, represents the flow cavity reserve coefficient; Indicates the total number of slices; represents the equivalent flow cavity diameter of the nth section; Represents the equivalent vessel wall diameter of the nth section.

[0071] S105: Determine the severity of mural thrombus by the flow reserve coefficient.

[0072] Through the above steps, the flow cavity reserve coefficient can be obtained , this coefficient can directly reflect the mural thrombus situation, that is, the severity. Specifically, after collecting a large amount of follow-up data, a scientific quantitative interval can be established according to the development and treatment of the patient's aneurysm. In a possible embodiment, the FLR is divided into three intervals: [0, A1), [A1, A2), and greater than or equal to A2. A1 represents the first preset threshold, and A2 represents the second preset threshold. A1 and A2 can be set according to actual conditions. Later, as the patient data increases, the corresponding interval thresholds can be optimized and updated.

[0073] Specifically, determining the severity of mural thrombus by flow cavity reserve coefficient may include the following steps:

[0074] When the cavity reserve coefficient is less than the first preset threshold, the severity level of the mural thrombus is low mural thrombus;

[0075] When the lumen reserve coefficient is greater than the first preset threshold value and less than the second preset threshold value, the severity level of the mural thrombus is moderate mural thrombus;

[0076] When the lumen reserve coefficient is greater than the second preset threshold, the severity level of the mural thrombus is high mural thrombus; wherein the first preset threshold is less than the second preset threshold.

[0077] Furthermore, the processor can also be used to send the above parameters (cavity reserve coefficient) and the severity level of mural thrombus to the memory, and the memory is used to store the above parameters and the severity level of mural thrombus. The processor can also send the cavity reserve coefficient and the severity level of mural thrombus to the display for display, so that the user can view the results.

[0078] At a later stage, the severity level of mural thrombus assessed by the present invention can be combined with existing key reference indicators such as the maximum diameter of the aneurysm and its annual growth rate to conduct a comprehensive assessment of the thrombus. For example, for aortic aneurysms larger than the clinical treatment standard of 5.0 cm, an appropriate treatment plan is generally selected according to the guidelines. The significance of this parameter (severity level of mural thrombus / flow cavity reserve coefficient) is that for patients with aortic aneurysms that are less than 5.0 cm but close to the clinical treatment standard, such as patients with a diameter of 4.0cm-5.0 cm, if the maximum diameter and growth rate of the aneurysm have not changed significantly during follow-up, but the flow cavity reserve coefficient has increased significantly, according to current research results, in this case, it is possible to consider increasing the frequency of follow-up or conducting treatment in advance to reduce the risk of aneurysm rupture.

[0079] The mural thrombus assessment method provided by the embodiment of the present invention is applied to a processor, and multiple sections are determined according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the lumen boundary, the mural thrombus and the lumen structure; the maximum diameter and minimum diameter of the lumen in the target section, and the maximum diameter and minimum diameter of the vascular wall are measured to obtain measurement results; the measurement results include the maximum lumen diameter, the minimum lumen diameter, the maximum vascular wall diameter and the minimum vascular wall diameter; the target section is any one of the multiple sections; the equivalent lumen diameter and the equivalent vascular wall diameter of the target section are calculated based on the measurement results; the lumen reserve coefficient is calculated based on the equivalent lumen diameter and the equivalent vascular wall diameter of the multiple sections; the severity level of the mural thrombus is determined by the lumen reserve coefficient. The lumen reserve coefficient FLR proposed by the present invention does not require complex and time-consuming operations such as model annotation and volume calculation analysis, and can be simply and efficiently analyzed with the help of commonly used measurement tools in clinical practice. At the same time, the FLR parameter can effectively reflect the severity of mural thrombus in aneurysms, providing additional basis for the clinical diagnosis and management of aortic aneurysms. Furthermore, based on the existing maximum aneurysm diameter and its growth rate parameters, the quantitative assessment of mural thrombus provided by the present invention is used to supplement the personalized assessment index of aneurysm risk, which is helpful for comprehensive and accurate clinical diagnosis and management of aneurysms and reduces the risk of aneurysm rupture; and the present invention has a simple calculation method, high analysis efficiency, and is easy to obtain and use in clinical practice.

[0080] The following is an introduction to a mural thrombus assessment device provided in an embodiment of the present invention. The mural thrombus assessment device described below and the mural thrombus assessment method described above can be referenced to each other.

[0081] Please refer to Figure 7 , Figure 7 A schematic structural diagram of a mural thrombus assessment device provided by an embodiment of the present invention may include:

[0082] The section extraction module 100 is used to determine multiple sections according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the cavity boundary, the mural thrombus and the cavity structure;

[0083] The measuring module 200 is used to measure the maximum diameter and the minimum diameter of the lumen in the target section, and the maximum diameter and the minimum diameter of the blood vessel wall to obtain a measurement result; the measurement result includes the maximum diameter of the lumen, the minimum diameter of the lumen, the maximum diameter of the blood vessel wall, and the minimum diameter of the blood vessel wall; the target section is any one of the multiple sections;

[0084] An equivalent diameter calculation module 300, used for calculating the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement results;

[0085] A lumen reserve coefficient calculation module 400, configured to calculate the lumen reserve coefficient based on the equivalent lumen diameter and the equivalent blood vessel wall diameter of a plurality of sections;

[0086] The evaluation module 500 is used to determine the severity level of the mural thrombus according to the lumen reserve coefficient.

[0087] Based on the above embodiment, the equivalent diameter calculation module 300 may include:

[0088] The equivalent flow cavity diameter calculation unit is used to calculate the equivalent flow cavity diameter according to Calculate and obtain the equivalent flow cavity diameter;

[0089] Equivalent vessel wall diameter calculation unit, used to calculate the equivalent vessel wall diameter according to Calculating and obtaining the equivalent blood vessel wall diameter;

[0090] in, It represents the equivalent flow cavity diameter; Indicates the maximum diameter of the flow cavity; Indicates the minimum diameter of the flow cavity; represents the equivalent vessel wall diameter; Indicates the maximum diameter of the blood vessel wall; Indicates the minimum diameter of the blood vessel wall.

[0091] Based on the above embodiment, the flow cavity reserve coefficient calculation module 400 may include:

[0092] The flow cavity reserve coefficient calculation unit is used to calculate the Calculating and obtaining the flow cavity reserve coefficient;

[0093] in, represents the flow cavity reserve coefficient; Indicates the total number of slices; represents the equivalent flow cavity diameter of the nth section; Represents the equivalent vessel wall diameter of the nth section.

[0094] Based on the above embodiment, the evaluation module 500 may include:

[0095] A first result unit, used for determining that the severity level of the mural thrombus is low mural thrombus when the lumen reserve coefficient is less than a first preset threshold value;

[0096] A second result unit is used for determining that the severity level of the mural thrombus is moderate mural thrombus when the lumen reserve coefficient is greater than the first preset threshold value and less than the second preset threshold value;

[0097] The third result unit is used for indicating that when the lumen reserve coefficient is greater than the second preset threshold, the severity level of the mural thrombus is high mural thrombus; wherein the first preset threshold is less than the second preset threshold.

[0098] Based on the above embodiment, the mural thrombus assessment device may further include:

[0099] A first data sending module, used for sending the lumen reserve coefficient and the severity level of the mural thrombus to a memory for storage;

[0100] The second data display module is used to send the lumen reserve coefficient and the severity level of the mural thrombus to a display for display.

[0101] It should be noted that the order of the modules and units in the above-mentioned mural thrombus assessment device can be changed without affecting the logic.

[0102] The mural thrombus evaluation device provided by the embodiment of the present invention comprises a section extraction module, a measurement module, an equivalent diameter calculation module, a lumen reserve coefficient calculation module and an evaluation module, wherein the section extraction module is used to determine multiple sections according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the lumen boundary, the mural thrombus and the lumen structure; the measurement module is used to measure the maximum diameter and the minimum diameter of the lumen in the target section, and the maximum diameter and the minimum diameter of the vascular wall to obtain a measurement result; the measurement result includes the maximum lumen diameter, the minimum lumen diameter, the maximum vascular wall diameter and the minimum vascular wall diameter; the target section is any one of the multiple sections; the equivalent diameter calculation module is used to calculate the equivalent lumen diameter and the equivalent vascular wall diameter of the target section based on the measurement result; the lumen reserve coefficient calculation module is used to calculate the lumen reserve coefficient based on the equivalent lumen diameter and the equivalent vascular wall diameter of the multiple sections; the evaluation module is used to determine the severity level of the mural thrombus through the lumen reserve coefficient. The flow cavity reserve coefficient FLR proposed in the present invention does not require complex and time-consuming operations such as model annotation and volume calculation and analysis. The analysis can be completed simply and efficiently with the help of commonly used measurement tools in clinical practice. At the same time, the FLR parameter can effectively reflect the severity of mural thrombus in aneurysms, providing an additional basis for the clinical diagnosis and management of aortic aneurysms. Furthermore, on the basis of the existing maximum aneurysm diameter and its growth rate parameters, the quantitative assessment of mural thrombus provided by the present invention is used to supplement the personalized assessment index of aneurysm risk, which is helpful for comprehensive and accurate clinical diagnosis and management of aneurysms and reduces the risk of aneurysm rupture. In addition, the present invention has a simple calculation method and high analysis efficiency, which is convenient for clinical acquisition and use.

[0103] The following is an introduction to a mural thrombus assessment device provided in an embodiment of the present invention. The mural thrombus assessment device described below and the mural thrombus assessment method described above can be referenced to each other.

[0104] Please refer to Figure 8 , Figure 8 A schematic structural diagram of a mural thrombus assessment device provided by an embodiment of the present invention may include:

[0105] A memory 10, used for storing computer programs;

[0106] The processor 20 is used to execute a computer program to implement the above-mentioned mural thrombus assessment method.

[0107] The memory 10 , the processor 20 , and the communication interface 31 all communicate with each other via the communication bus 32 .

[0108] In the embodiment of the present invention, the memory 10 is used to store one or more programs, and the program may include program code, and the program code includes computer operation instructions. In the embodiment of the present invention, the memory 10 may store programs for implementing the following functions:

[0109] Determine multiple sections according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the cavity boundary, the mural thrombus and the cavity structure;

[0110] The maximum diameter and the minimum diameter of the lumen in the target section, as well as the maximum diameter and the minimum diameter of the blood vessel wall are measured to obtain measurement results; the measurement results include the maximum diameter of the lumen, the minimum diameter of the lumen, the maximum diameter of the blood vessel wall, and the minimum diameter of the blood vessel wall; the target section is any one of the multiple sections;

[0111] Based on the measurement results, the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section are calculated;

[0112] The lumen reserve coefficient was calculated based on the equivalent lumen diameter and equivalent vascular wall diameter of multiple sections;

[0113] The severity of mural thrombus was determined by the flow reserve coefficient.

[0114] In a possible implementation, the memory 10 may include a program storage area and a data storage area, wherein the program storage area may store an operating system and an application required for at least one function, etc.; the data storage area may store data created during use.

[0115] In addition, the memory 10 may include a read-only memory and a random access memory, and provide instructions and data to the processor. A portion of the memory may also include an NVRAM. The memory stores an operating system and operating instructions, executable modules or data structures, or a subset thereof, or an extended set thereof, wherein the operating instructions may include various operating instructions for implementing various operations. The operating system may include various system programs for implementing various basic tasks and processing hardware-based tasks.

[0116] The processor 20 may be a central processing unit (CPU), an application specific integrated circuit, a digital signal processor, a field programmable gate array or other programmable logic device, a microprocessor or any conventional processor, etc. The processor 20 may call a program stored in the memory 10 .

[0117] The communication interface 31 may be an interface of a communication module, and is used to connect to other devices or systems.

[0118] Of course, it should be noted that Figure 8 The structure shown does not constitute a limitation on the mural thrombus assessment device in the embodiment of the present invention. In actual applications, the mural thrombus assessment device may include Figure 8 More or fewer components than shown, or combinations of certain components.

[0119] The computer-readable storage medium provided in an embodiment of the present invention is introduced below. The computer-readable storage medium described below and the mural thrombus assessment method described above can be referenced to each other.

[0120] The present invention also provides a computer-readable storage medium, on which a computer program is stored. When the computer program is executed by a processor, the steps of the above-mentioned mural thrombus assessment method are implemented.

[0121] The computer-readable storage medium may include: a USB flash drive, a mobile hard disk, a read-only memory (ROM), a random access memory (RAM), a magnetic disk or an optical disk, and other media that can store program codes.

[0122] In this specification, each embodiment is described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the embodiments can be referred to each other. For the device disclosed in the embodiment, since it corresponds to the method disclosed in the embodiment, the description is relatively simple, and the relevant parts can be referred to the method part.

[0123] Professionals may further appreciate that the units and algorithm steps of each example described in conjunction with the embodiments disclosed herein can be implemented in electronic hardware, computer software, or a combination of the two. In order to clearly illustrate the interchangeability of hardware and software, the composition and steps of each example have been generally described in the above description according to function. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Professionals and technicians may use different methods to implement the described functions for each specific application, but such implementation should not be considered to be beyond the scope of the present invention.

[0124] Finally, it should be noted that, in this article, relationships such as first and second, etc. are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprises" or any other variations are intended to cover non-exclusive inclusion, so that a process, method, article or device that includes a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0125] The above is a detailed introduction to a mural thrombus assessment method, device, equipment and readable storage medium provided by the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for a person skilled in the art, according to the idea of ​​the present invention, there will be changes in the specific implementation method and application scope. In summary, the content of this specification should not be understood as a limitation on the present invention.

Claims

1. A mural thrombus assessment device, characterized in that: include: A section extraction module is used to determine multiple sections according to the size of the tumor in the target part image; The section includes the blood vessel wall boundary, the lumen boundary, the mural thrombus and the lumen structure; A measuring module, used for measuring the maximum diameter and minimum diameter of the lumen in the target section, and the maximum diameter and minimum diameter of the blood vessel wall, to obtain a measurement result; the measurement result includes the maximum diameter of the lumen, the minimum diameter of the lumen, the maximum diameter of the blood vessel wall, and the minimum diameter of the blood vessel wall; the target section is any one of the multiple sections; An equivalent diameter calculation module, used for calculating the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement results; A lumen reserve coefficient calculation module, used for calculating the lumen reserve coefficient based on the equivalent lumen diameter and equivalent blood vessel wall diameter of multiple sections; An evaluation module is used to determine the severity level of the mural thrombus according to the flow cavity reserve coefficient.

2. The mural thrombus assessment device according to claim 1, characterized in that: Equivalent diameter calculation module, including: The equivalent flow cavity diameter calculation unit is used to calculate the equivalent flow cavity diameter according to Calculate and obtain the equivalent flow cavity diameter; Equivalent vessel wall diameter calculation unit, used to calculate the equivalent vessel wall diameter according to Calculating and obtaining the equivalent blood vessel wall diameter; in, It represents the equivalent flow cavity diameter; Indicates the maximum diameter of the flow cavity; Indicates the minimum diameter of the flow cavity; represents the equivalent vessel wall diameter; Indicates the maximum diameter of the blood vessel wall; Indicates the minimum diameter of the blood vessel wall.

3. The mural thrombus assessment device according to claim 1, characterized in that: Flow cavity reserve coefficient calculation module, including: The flow cavity reserve coefficient calculation unit is used to calculate the Calculating and obtaining the flow cavity reserve coefficient; in, represents the flow cavity reserve coefficient; Indicates the total number of slices; represents the equivalent flow cavity diameter of the nth section; Represents the equivalent vessel wall diameter of the nth section.

4. The mural thrombus assessment device according to claim 1, characterized in that: Assessment modules include: A first result unit, used for determining that the severity level of the mural thrombus is low mural thrombus when the lumen reserve coefficient is less than a first preset threshold value; A second result unit is used for determining that the severity level of the mural thrombus is moderate mural thrombus when the lumen reserve coefficient is greater than the first preset threshold value and less than the second preset threshold value; The third result unit is used for indicating that when the lumen reserve coefficient is greater than the second preset threshold, the severity level of the mural thrombus is high mural thrombus; wherein the first preset threshold is less than the second preset threshold.

5. The mural thrombus assessment device according to claim 1, characterized in that: Also includes: A first data sending module, used for sending the lumen reserve coefficient and the severity level of the mural thrombus to a memory for storage; The second data display module is used to send the lumen reserve coefficient and the severity level of the mural thrombus to a display for display.

6. A method for evaluating mural thrombus, characterized in that: Applicable to processors, including: Determine multiple sections according to the size of the tumor in the target part image; the sections include the vascular wall boundary, the cavity boundary, the mural thrombus and the cavity structure; The maximum diameter and the minimum diameter of the lumen in the target section, as well as the maximum diameter and the minimum diameter of the blood vessel wall are measured to obtain measurement results; the measurement results include the maximum diameter of the lumen, the minimum diameter of the lumen, the maximum diameter of the blood vessel wall, and the minimum diameter of the blood vessel wall; the target section is any one of the multiple sections; Calculate the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement results; Calculate the lumen reserve coefficient based on the equivalent lumen diameter and the equivalent blood vessel wall diameter of multiple sections; The severity of the mural thrombus is determined by the flow reserve coefficient.

7. The mural thrombus assessment method according to claim 6, characterized in that: Calculating the equivalent lumen diameter and the equivalent blood vessel wall diameter of the target section based on the measurement results includes: according to Calculate and obtain the equivalent flow cavity diameter; according to Calculating and obtaining the equivalent blood vessel wall diameter; in, It represents the equivalent flow cavity diameter; Indicates the maximum diameter of the flow cavity; Indicates the minimum diameter of the flow cavity; represents the equivalent vessel wall diameter; Indicates the maximum diameter of the blood vessel wall; Indicates the minimum diameter of the blood vessel wall.

8. The mural thrombus assessment method according to claim 6, characterized in that: The severity of mural thrombus is determined by the flow reserve coefficient, including: When the lumen reserve coefficient is less than the first preset threshold, the severity level of the mural thrombus is low mural thrombus; When the lumen reserve coefficient is greater than the first preset threshold value and less than the second preset threshold value, the severity level of the mural thrombus is moderate mural thrombus; When the lumen reserve coefficient is greater than the second preset threshold, the severity level of the mural thrombus is high mural thrombus; wherein the first preset threshold is less than the second preset threshold.

9. A mural thrombus assessment device, characterized in that: include: Memory for storing computer programs; A processor, configured to implement the mural thrombus assessment method according to any one of claims 6 to 8 when executing the computer program.

10. A computer-readable storage medium, characterized in that: The computer-readable storage medium stores computer-executable instructions, and when the computer-executable instructions are loaded and executed by the processor, the mural thrombus assessment method according to any one of claims 6 to 8 is implemented.

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