Hydrophilic PMMA composition, preparation method and application

Abstract

The invention belongs to the technical field of high polymer materials, and particularly relates to a hydrophilic PMMA composition, a preparation method and application. The hydrophilic PMMA composition is prepared from the following raw materials in parts by weight: 90-96 parts of PMMA resin, 2-6 parts of a hydrophilic auxiliary agent, 0-3 parts of a compatilizer and 0.2 part of an antioxidant, the hydrophilic auxiliary agent is prepared from the following raw materials in parts by weight: 0 to 4 parts of alkyl sulfonate, 1.5 to 2 parts of glyceryl monostearyl ester, 0.5 to 2 parts of ethoxylamine and 0 to 4 parts of erucyl amide; the hydrophilic PMMA composition prepared by the invention has better compatible toughness and better hydrophilicity, the transparency can be adjusted by compounding auxiliaries, and the hydrophilic PMMA composition can be used as a hydrophilic material for preparing medical consumables.

Description

Technical Field

[0001] The invention belongs to the technical field of polymer materials, and in particular relates to a hydrophilic PMMA composition, a preparation method and an application thereof. Background Art

[0002] In our daily life, we often see that the consumables used in hospitals and medical in vitro testing and analysis rooms often need to have the following characteristics: 1. Transparency; 2. Hydrophilicity; 3. Convenient manufacturability; 4. Convenient sterilization; 5. Low biological cytotoxicity; Therefore, for a long time, hospitals have used a large number of glass products, and the fragile nature of glass products can easily lead to the loss of liquid samples and cause secondary accidents. With the advancement of technology, the optimization of material synthesis processes, and the upgrading of post-processing methods, more and more plastic products are gradually replacing glass products in hospitals.

[0003] Polymethyl methacrylate has the advantages of high transparency, low price, easy machining, etc., with a refractive index of 1.49 and a specific gravity of 1.19g / cm3. It is a commonly used glass substitute material. As a transparent plastic, it is characterized by high light transmittance, 90-92% of ordinary light can pass through, 73-76% of ultraviolet light can pass through, while ordinary glass can only pass through 0.6% of ultraviolet light, so it is also called organic glass, and its application is mostly concentrated in the field of optical products; however, due to the nature of the material itself, the hydrophilicity, fluidity and toughness of conventional polymethyl methacrylate are not very good. Summary of the invention

[0004] In view of the deficiencies of the prior art, the present invention provides a hydrophilic PMMA composition, a preparation method and an application thereof. The purpose of the present invention can be achieved by the following technical solutions:

[0005] A hydrophilic PMMA composition comprises the following raw materials in parts by weight:

[0006] 90-96 parts of PMMA resin, 2-6 parts of hydrophilic additive, 0-3 parts of compatibilizer and 0.2 parts of antioxidant;

[0007] The hydrophilic adjuvant comprises the following raw materials in parts by weight: 0-4 parts of alkyl sulfonate, 1.5-2 parts of glycerol monostearyl ester, 0.5-2 parts of ethoxylated amine and 0-4 parts of erucamide.

[0008] Preferably, the melt flow rate of the PMMA resin is 15 to 20 g / 10 min.

[0009] Preferably, the compatibilizer is a PMMA graft.

[0010] Preferably, the antioxidant includes one or more of antioxidant 1076 and antioxidant 168.

[0011] A method for preparing a hydrophilic PMMA composition comprises the following steps:

[0012] 90-96 parts of PMMA resin, 2-6 parts of hydrophilic additives, 0-3 parts of compatibilizers and 0.2 parts of antioxidants are mixed, extruded, granulated, cooled and air-dried to obtain a hydrophilic PMMA composition.

[0013] Preferably, the extrusion temperature is 200-230°C.

[0014] Preferably, the melt flow rate of the PMMA resin is 15 to 20 g / 10 min.

[0015] Preferably, the compatibilizer is a PMMA graft.

[0016] Preferably, the antioxidant includes one or more of antioxidant 1076 and antioxidant 168.

[0017] Application of the hydrophilic PMMA composition or the hydrophilic PMMA composition prepared by the method described above in the production of medical consumables.

[0018] Beneficial effects of the present invention:

[0019] 1. The hydrophilic PMMA composition prepared by the present invention has good hydrophilicity, a simple preparation method, and can be formed into a liquid collection tube. Liquid can be quickly collected through a capillary effect, thereby replacing glass equipment and having the characteristic of being not easily damaged.

[0020] 2. The hydrophilic PMMA composition prepared by the present invention has good fluidity and hydrophilicity, and can be used to prepare medical test strips and medical in vitro fluid collection consumables, which can ensure both good molding performance and the use characteristics of the shell material. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention are described clearly and completely. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] The specific information of the raw materials used in the following examples and comparative examples is as follows:

[0023] PMMA resin, manufactured by Wanhua Chemical, brand SF01;

[0024] Alkyl sulfonate, produced by Cargill Bioindustries, brand name ATMER 190;

[0025] Glycerol monostearyl ester, produced by Cargill Bioindustries, brand name ATMER 129;

[0026] Ethoxylated amines, manufactured by Cargill Bioindustries, brand name ATMER 262;

[0027] Erucamide, manufactured by Cargill Bioindustries, brand name OPTISLIP ER;

[0028] Transparent compatibilizer, manufactured by Jindaquan, brand A-866;

[0029] Antioxidant: BASF 1076 and 168 are compounded in a mass ratio of 1:2;

[0030] Example 1

[0031] 94 parts of PMMA resin and 2 parts of ethoxylated amine are initially mixed for 30 seconds, and then 2 parts of glycerol monostearate, 2 parts of erucamide and 0.2 parts of antioxidant are added, mixed in a low mixing pot to obtain a mixture, and then added to a twin-screw extruder. After the material is melted in the twin-screw extruder, it is extruded and granulated through the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0032] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and the screw speed is 400rpm.

[0033] Example 2

[0034] 93 parts of PMMA resin and 2 parts of ethoxylated amine are initially mixed for 30 seconds, and then 2 parts of glycerol monostearate, 2 parts of erucamide and 0.2 parts of antioxidant are added, mixed in a low mixing pot to obtain a mixture, and then added to a twin-screw extruder. After the material is melted in the twin-screw extruder, it is extruded and granulated through the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0035] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and the screw speed is 400rpm.

[0036] Example 3

[0037] 93 parts of PMMA resin and 0.5 parts of ethoxylated amine are initially mixed for 30 seconds, and then 1.5 parts of glycerol monostearate, 4 parts of erucamide and 0.2 parts of antioxidant are added, mixed in a low mixing pot to obtain a mixture, and then added to a twin-screw extruder. After the material is melted in the twin-screw extruder, it is extruded and granulated through the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0038] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and the screw speed is 400rpm.

[0039] Example 4

[0040] 90 parts of PMMA resin and 0.5 parts of ethoxylated amine are initially mixed for 30 seconds, and then 4 parts of alkyl sulfonate, 1.5 parts of glycerol monostearyl ester, 2 parts of erucamide and 0.2 parts of antioxidant are added, mixed in a low mixing pot to obtain a mixture, and then added to a twin-screw extruder. After the material is melted in the twin-screw extruder, it is extruded and granulated by the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0041] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and the screw speed is 400rpm.

[0042] Example 5

[0043] 93 parts of PMMA resin and 0.5 parts of ethoxylated amine are initially mixed for 30 seconds, and then 4 parts of alkyl sulfonate, 1.5 parts of glycerol monostearyl ester and 0.2 parts of antioxidant are added, mixed in a low mixing pot to obtain a mixture, and then added to a twin-screw extruder. After the material is melted in the twin-screw extruder, it is extruded and granulated through the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0044] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and the screw speed is 400rpm.

[0045] Example 6

[0046] 90 parts of PMMA resin and 2 parts of ethoxylated amine are initially mixed for 30 seconds, and then 4 parts of alkyl sulfonate, 1.5 parts of glycerol monostearyl ester, 3 parts of transparent compatibilizer and 0.2 parts of antioxidant are added, mixed in a low mixing pot to obtain a mixture, and then added into a twin-screw extruder at the same time. After the material is melted in the twin-screw extruder, it is extruded and granulated by the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0047] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and the screw speed is 400rpm.

[0048] Comparative Example 1

[0049] 96 parts of PMMA resin and 2 parts of ethoxylated amine are initially mixed for 30 seconds, and then 2 parts of glycerol monostearate and 0.2 parts of antioxidant are added, mixed in a low mixing pot to obtain a mixture, and then added to a twin-screw extruder. After the material is melted in the twin-screw extruder, it is extruded and granulated through the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0050] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and the screw speed is 400rpm.

[0051] Comparative Example 2

[0052] 94 parts of PMMA resin, 6 parts of alkyl sulfonate and 0.2 parts of antioxidant are mixed in a low mixing pot to obtain a mixture, and then added into a twin-screw extruder. After the materials are melted in the twin-screw extruder, they are extruded and granulated through the extruder, and then cooled and air-dried to obtain a hydrophilic PMMA composition.

[0053] Among them, the screw aspect ratio of the twin-screw extruder is 40:1, and the melt extrusion conditions of the twin-screw extruder are: zone one temperature 200°C, zone two temperature 210°C, zone three temperature 220°C, zone four temperature 220°C, zone five temperature 210°C, zone six temperature 210°C, zone seven temperature 220°C, zone eight temperature 220°C, zone nine temperature 230°C, and screw speed 200rpm.

[0054]

[0055]

[0056] The obtained hydrophilic PMMA composition was subjected to performance testing, and the testing standards were as follows:

[0057] Melt flow rate, according to GB / T3682230℃×3.8kg

[0058] Izod notch impact, according to GB / T1843 pendulum 2.75J, room temperature 23℃

[0059] Static contact angle, according to GB / T 30693-2014, molding color plate test

[0060] Dyne value, according to GB / T 1633-2000, molding color plate test

[0061] Light transmittance, according to GB / T 9721, 3mm thick color plate test

[0062] The results of the measurement are shown in Table 1.

[0063] Table 1

[0064]

[0065] By comparing the data in Table 1, it can be seen that when alkyl sulfonate is added into the system, the transparency of the material decreases significantly, but its improvement on hydrophilicity is the most obvious; glycerol monostearyl ester, ethoxylated amine, and erucic acid amide have little effect on the transparency of the material; hydrophilic additives are easy to absorb moisture on the surface of the material due to their strong hydrophilic effect, and some strong polar groups can easily combine with water through hydrogen bonds to form some conductive paths, achieving an antistatic effect, which can effectively prevent dust from gathering on the surface of the material. At the same time, the addition of hydrophilic additives greatly improves the interface properties of PMMA and enhances the adhesion with other plastic materials. Whether it is two-color injection molding or laser welding, the bonding strength between the two materials can be significantly improved; at the same time, appropriate transparent compatibilizers can improve the toughness of the material and the injection molding delamination phenomenon, avoid the brittle fracture and snakeskin pattern phenomenon of translucent materials, and at the same time can slightly improve the hydrophilicity of the material.

[0066] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0067] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments, and the above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected.

Claims

1. A hydrophilic PMMA composition, characterized in that: It includes the following raw materials in parts by weight: 90-96 parts of PMMA resin, 2-6 parts of hydrophilic additive, 0-3 parts of compatibilizer and 0.2 parts of antioxidant; The hydrophilic adjuvant comprises the following raw materials in parts by weight: 0-4 parts of alkyl sulfonate, 1.5-2 parts of glycerol monostearyl ester, 0.5-2 parts of ethoxylated amine and 0-4 parts of erucamide.

2. A hydrophilic PMMA composition according to claim 1, characterized in that: The melt flow rate of the PMMA resin is 15 to 20 g / 10 min.

3. A hydrophilic PMMA composition according to claim 1, characterized in that: The compatibilizer is a PMMA graft.

4. A hydrophilic PMMA composition according to claim 1, characterized in that: The antioxidant includes one or more of the antioxidant 1076 and the antioxidant 168 .

5. A method for preparing a hydrophilic PMMA composition, characterized in that: The following steps are involved: 90-96 parts of PMMA resin, 2-6 parts of hydrophilic additive, 0-3 parts of compatibilizer and 0.2 parts of antioxidant are mixed, extruded, granulated, cooled and air-dried to obtain a hydrophilic PMMA composition.

6. The method for preparing the hydrophilic PMMA composition according to claim 5, characterized in that: The extrusion temperature is 200-230°C.

7. The method for preparing the hydrophilic PMMA composition according to claim 5, characterized in that: The melt flow rate of the PMMA resin is 15 to 20 g / 10 min.

8. The method for preparing the hydrophilic PMMA composition according to claim 5, characterized in that: The compatibilizer is a PMMA graft.

9. The method for preparing the hydrophilic PMMA composition according to claim 5, characterized in that: The antioxidant includes one or more of the antioxidant 1076 and the antioxidant 168 .

10. Use of the hydrophilic PMMA composition according to any one of claims 1 to 4 or the hydrophilic PMMA composition prepared by the method according to claims 5 to 9 in the production of medical consumables.

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