Cyclocarya paliurus, radix puerariae and folium mori capsule and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine, in particular to cyclocarya paliurus, radix puerariae and folium mori capsules and a preparation method thereof.The preparation method comprises the steps that dried radix puerariae, dried folium mori and cyclocarya paliurus are extracted to prepare a radix puerariae and folium mori concentrated solution and a cyclocarya paliurus concentrated solution; combining the radix puerariae and folium mori concentrated solution and the cyclocarya paliurus concentrated solution, performing steam concentration until the water content is less than 5%, performing crushing to obtain dry paste powder, mixing the dry paste powder with chromium-enriched yeast, microcrystalline cellulose and silicon dioxide, and performing capsule filling on the mixed material to obtain the cyclocarya paliurus, radix puerariae and folium mori capsules. The cyclocarya paliurus, radix puerariae and folium mori capsules are easy to prepare, low in cost and capable of assisting in reducing blood sugar, the cyclocarya paliurus, radix puerariae and folium mori capsules are prepared from radix puerariae, folium mori and cyclocarya paliurus, and the health care effect is good.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine, and in particular to a Cyclocarya paliurus, Pueraria lobata, and mulberry leaf capsule and a preparation method thereof. Background Art

[0002] At present, the effective ingredients of Cyclocarya paliurus in tea powder or tea bags on the market have not been fully extracted. The user's body cannot quickly absorb the effective ingredients of Cyclocarya paliurus after drinking, so that the health care and therapeutic effect of Cyclocarya paliurus is slow and not significant. In addition, during the drinking process, this type of Cyclocarya paliurus tea tastes bitter and difficult to drink. Summary of the invention

[0003] The invention aims to provide a Cyclocarya paliurus, Pueraria root and mulberry leaf capsule and a preparation method thereof.

[0004] To achieve the above object, the present invention provides the following technical solutions:

[0005] A method for preparing Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsules comprises the following steps:

[0006] S1, chopping dried kudzu root and mulberry leaf, soaking them in water, filtering and concentrating them to obtain kudzu root and mulberry leaf concentrate;

[0007] S2, chopping the dried Cyclocarya paliurus into pieces, soaking the pieces in water, filtering, and concentrating the pieces to obtain a Cyclocarya paliurus concentrate;

[0008] S3, combining the obtained Pueraria lobata mulberry leaf concentrate and Cyclocarya paliurus concentrate, performing steam concentration, spray drying, crushing and screening to obtain a dry paste powder;

[0009] S4, taking the dry paste powder and mixing it with chromium-enriched yeast, microcrystalline cellulose, magnesium stearate and silicon dioxide, and filling the mixed materials into capsules to prepare Cyclocarya paliurus, Pueraria lobata and mulberry leaf capsules.

[0010] Furthermore, the chopping in step S1 and the chopping in step S2 are both cut into pieces with a length not exceeding 2 cm.

[0011] Furthermore, in step S1, the mass ratio of the kudzu root and the mulberry leaf is 1:1, the water temperature for soaking is 95° C.-100° C., and the soaking time is 24-72 hours.

[0012] Furthermore, the water temperature for soaking in step S2 is 95° C.-100° C., and the soaking time is 24-48 hours.

[0013] Furthermore, the steam temperature of the steam concentration in step S3 is 100° C., and the concentration time is 3-4 hours.

[0014] Furthermore, the spray drying temperature in step S3 is 115-125°C.

[0015] Furthermore, the mesh size of the crushing and screening in step S3 is 80 meshes.

[0016] Furthermore, the chromium-enriched yeast, microcrystalline cellulose, magnesium stearate and silicon dioxide in step S4 are all materials that can pass through an 80-mesh sieve.

[0017] Furthermore, the mass ratio of the dry paste powder to chromium-enriched yeast, microcrystalline cellulose, magnesium stearate and silicon dioxide in step S4 is 500:4:2:1:1.

[0018] The present invention also includes a Cyclocarya paliurus, Pueraria lobata and mulberry leaf capsule, which is prepared by the preparation method described in any one of the above claims.

[0019] Compared with the prior art, the present invention provides a Cyclocarya paliurus, Pueraria root, mulberry leaf capsule which is simple to prepare, low in cost and can assist in lowering blood sugar, and a preparation method thereof. The Cyclocarya paliurus, Pueraria root, mulberry leaf and Cyclocarya paliurus are used to prepare the Cyclocarya paliurus, Pueraria root, mulberry leaf and Cyclocarya paliurus, which has a good health-care effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 The changes of blood sugar in the test group and the control group 2 hours before and after the test. DETAILED DESCRIPTION

[0021] The technical scheme of the present invention is further described below in conjunction with specific examples. It should be understood that the following examples are only exemplary descriptions and explanations of the present invention, and should not be construed as limiting the scope of protection of the present invention. All technologies implemented based on the above content of the present invention are included in the scope that the present invention is intended to protect.

[0022] Example 1

[0023] A Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsule is prepared according to the following steps:

[0024] S1, chopping dried kudzu root and mulberry leaf in a mass ratio of 1:1 into pieces not exceeding 2 cm in length, soaking in water at 95° C.-100° C. for 24-72 hours, filtering, and concentrating to obtain a kudzu root and mulberry leaf concentrate;

[0025] S2, chopping the dried Cyclocarya paliurus into pieces not exceeding 2 cm in length, soaking them in water at 95° C. to 100° C. for 24 to 48 hours, filtering, and concentrating to obtain a Cyclocarya paliurus concentrate;

[0026] S3, combining the obtained Pueraria lobata mulberry leaf concentrate and Cyclocarya paliurus concentrate, concentrating under 100° C. steam for 3-4 hours, spray drying at 115-125° C., and crushing through an 80-mesh sieve to obtain a dry paste powder;

[0027] S4, taking the dry paste powder and mixing it with chromium-rich yeast that can pass through an 80-mesh sieve, microcrystalline cellulose, magnesium stearate and silicon dioxide in a mass ratio of 500:4:2:1:1, and filling the mixed materials into capsules to prepare Cyclocarya paliurus, Pueraria lobata and mulberry leaf capsules.

[0028] Example 2

[0029] A Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsule is prepared according to the following steps:

[0030] S1, chopping dried kudzu root and mulberry leaf in a mass ratio of 1:1 into pieces not exceeding 2 cm in length, soaking in water at 95°C-100°C for 24-72 hours, filtering, and concentrating to obtain a kudzu root and mulberry leaf concentrate having a density of 1.10-1.15;

[0031] S2, chopping the dried Cyclocarya paliurus into pieces not exceeding 2 cm in length, soaking them in water at 95° C. to 100° C. for 24 to 48 hours, filtering, and concentrating to obtain a Cyclocarya paliurus concentrate having a density of 1.20 to 1.30;

[0032] S3, combining the obtained Pueraria lobata mulberry leaf concentrate and Cyclocarya paliurus concentrate in a ratio of 1:1, concentrating under 100° C. steam for 3-4 hours, spray drying at 115-125° C., and crushing through an 80-mesh sieve to obtain a dry paste powder;

[0033] S4, taking the dry paste powder and mixing it with chromium-rich yeast that can pass through an 80-mesh sieve, microcrystalline cellulose, magnesium stearate and silicon dioxide in a mass ratio of 500:4:2:1:1, and filling the mixed materials into capsules to prepare Cyclocarya paliurus, Pueraria lobata and mulberry leaf capsules.

[0034] Example 3

[0035] A Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsule is prepared according to the following steps:

[0036] S1, chopping 175 kg of dried kudzu root and 175 kg of mulberry leaves into pieces not exceeding 2 cm in length, soaking them in 6.3 tons of water at 98° C. for 48 hours, filtering, and concentrating to obtain a kudzu root and mulberry leaf concentrate having a density of 1.10-1.15;

[0037] S2, chopping 289 kg of dried Cyclocarya paliurus into pieces not exceeding 2 cm in length, soaking them in 98° C. water for 36 hours, filtering, and concentrating to obtain a Cyclocarya paliurus concentrate having a density of 1.20-1.30;

[0038] S3, combining the obtained Pueraria lobata mulberry leaf concentrate and Cyclocarya paliurus concentrate in a ratio of 1:1, concentrating under 100° C. steam for 3.5 h, spray drying at 120° C., and crushing through an 80-mesh sieve to obtain a dry paste powder;

[0039] S4, taking the dry paste powder and mixing it with chromium-rich yeast that can pass through an 80-mesh sieve, microcrystalline cellulose, magnesium stearate and silicon dioxide in a mass ratio of 500:4:2:1:1, and filling the mixed materials into capsules at 0.5g±7.5% per capsule to obtain the example Cyclocarya paliurus, Pueraria lobata and mulberry leaf capsules.

[0040] Fasting blood sugar and 2h postprandial blood sugar abnormalities were collected from adult hyperglycemia populations, and 110 volunteers were screened and randomly divided into a trial group and a control group, with 55 cases in the control group and 55 cases in the trial group. The main factors affecting the results such as age, gender, course of disease, and type of medication were considered during grouping, and a balance test was conducted to ensure the comparability between the groups. (A total of 7 cases dropped out of the two groups, including 3 cases in the control group and 4 cases in the trial group). The actual number of participants who completed the study: 52 cases in the control group and 51 cases in the trial group.

[0041] The trial group took Cyclocarya paliurus, Pueraria lobata and mulberry leaf capsules.

[0042] The control group was blank control.

[0043] Changes in blood sugar two hours after meal: Blood sugar levels of volunteers were tested two hours after eating 100g of refined flour steamed bread.

[0044] See also Figure 1 The blood glucose level of the trial group 2 hours after the meal was significantly lower than that before the trial; there was no significant difference in the blood glucose level of the control group before and 2 hours after the trial.

[0045] Although the specific implementation modes of the present invention are described above, those skilled in the art should understand that the specific implementation modes described are only illustrative and are not intended to limit the scope of the present invention. Any modifications and changes made by those skilled in the art in accordance with the spirit of the present invention should be included in the scope of protection of the claims of the present invention.

Claims

1. A method for preparing Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsules, characterized in that: The following steps are involved: S1, chopping dried kudzu root and mulberry leaf, soaking them in water, filtering and concentrating them to obtain kudzu root and mulberry leaf concentrate; S2, chopping the dried Cyclocarya paliurus into pieces, soaking the pieces in water, filtering, and concentrating the pieces to obtain a Cyclocarya paliurus concentrate; S3, combining the obtained Pueraria lobata mulberry leaf concentrate and Cyclocarya paliurus concentrate, performing steam concentration, spray drying, crushing and screening to obtain a dry paste powder; S4, taking the dry paste powder and mixing it with chromium-enriched yeast, microcrystalline cellulose, magnesium stearate and silicon dioxide, and filling the mixed materials into capsules to prepare Cyclocarya paliurus, Pueraria lobata and mulberry leaf capsules.

2. The method for preparing the Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsules according to claim 1, characterized in that: The chopping in step S1 and the chopping in step S2 are both cut into pieces with a length not exceeding 2 cm.

3. The method for preparing the Cyclocarya paliurus, Puerariae and Mulberry Leaf Capsule according to claim 1, characterized in that: In step S1, the mass ratio of the kudzu root and the mulberry leaf is 1:1, the water temperature for soaking is 95° C.-100° C., and the soaking time is 24-72 hours.

4. The method for preparing the Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsules according to claim 1, characterized in that: The water temperature for soaking in step S2 is 95° C.-100° C., and the soaking time is 24-48 hours.

5. The method for preparing the Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsules according to claim 1, characterized in that: The steam temperature of the steam concentration in step S3 is 100° C., and the concentration time is 3-4 hours.

6. The method for preparing the Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsules according to claim 1, characterized in that: The spray drying temperature in step S3 is 115-125°C.

7. The method for preparing the Cyclocarya paliurus, Puerariae and Mulberry Leaf Capsules according to claim 1, characterized in that: The mesh size of the crushing and screening in step S3 is 80 meshes.

8. The method for preparing the Cyclocarya paliurus, Puerariae and Mulberry Leaf Capsules according to claim 1, characterized in that: The chromium-enriched yeast, microcrystalline cellulose, magnesium stearate and silicon dioxide in step S4 are all materials that can pass through an 80-mesh sieve.

9. The method for preparing the Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsules according to claim 1, characterized in that: The mass ratio of the dry paste powder to chromium-enriched yeast, microcrystalline cellulose, magnesium stearate and silicon dioxide in step S4 is 500:4:2:1:

1.

10. A Cyclocarya paliurus, Puerariae, and Mulberry Leaf Capsule, characterized by: Cyclocarya paliurus, kudzu root and mulberry leaf capsules prepared by the preparation method described in any one of claims 1 to 9.

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