PET detection device, PET system and PET detection method

By introducing movable detector modules and robotic arm systems into the PET system, adjusting the position and size of the detector ring, the problem of insufficient sensitivity in local imaging of the existing PET system is solved, and high-resolution imaging is achieved. And reduce clinical diagnosis and treatment costs and equipment needs.

CN119214673APending Publication Date: 2024-12-31TSINGHUA UNIVERSITY
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Patent Information

Application Number
CN202411503985.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-25
Publication Date
2024-12-31

AI Technical Summary

Technical Problem

It is difficult for existing PET systems to adjust the size and position of the detector ring when performing local imaging, resulting in insufficient sensitivity and increasing the cost of clinical diagnosis and treatment.

Method used

A PET detection device is designed, including a movable detector module and a robotic arm system, which can adjust the position and size of the detector ring in the detection hole to adapt to the imaging needs of different body parts.

Benefits of technology

High-resolution local imaging is achieved, which reduces the cost of clinical diagnosis and treatment, reduces the demand for special PET equipment, and saves hospital resources.

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Abstract

The invention provides a PET detection device, a PET system and a PET detection method. According to the invention, the PET detection device comprises a rack, the rack is provided with a detection hole penetrating through the rack, and a moving part capable of extending into the detection hole is arranged in the rack; a plurality of detector modules, the plurality of detector modules are arranged on the moving part, the moving part can drive each detector module to move in the detection hole, and the moving part moves the corresponding detector module to a preset position so as to form at least one detector ring in the detection hole; and each detector ring is surrounded by at least part of the plurality of detector modules. Therefore, the PET detection device provided by the embodiment of the invention has the advantage of conveniently meeting the spatial resolution required by local imaging.
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Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a PET detection device, a PET system and a PET detection method. Background Art

[0002] The PET (positron emission tomography) system can reconstruct images reflecting the physiological functions of radioactive tracers in the living body based on the distribution information of the radioactive tracer, and has become one of the indispensable tools for clinical diagnosis and treatment. In the related art, the PET system is designed to perform whole-body imaging to capture the distribution of tracers throughout the body. It requires a larger detector ring aperture, usually surrounded by multiple detectors to form a fixed ring structure. However, with the development of radioactive drugs and the improvement of detector accuracy, PET is increasingly used for imaging of local areas such as nerves and heart. When performing local imaging, it is necessary to reduce the ring radius and adjust the field of view to increase the sensitivity of the system. Therefore, it is necessary to adjust the detector ring accordingly for specific imaging sites to achieve high-resolution local imaging. In the related art, by developing PET dedicated to local imaging, such as a dedicated PET system for the brain, this further increases the cost of clinical diagnosis and treatment. Summary of the invention

[0003] The present invention aims to solve one of the technical problems in the related art at least to a certain extent.

[0004] To this end, embodiments of the present invention provide a PET detection device, a PET system, and a PET detection method.

[0005] A PET detection device according to an embodiment of the present invention includes:

[0006] A frame, wherein the frame has a detection hole extending therethrough, and a movable portion is disposed in the frame and can extend into the detection hole;

[0007] Multiple detector modules are arranged on the moving part, and the moving part can drive each detector module to move in the detection hole. The moving part moves the corresponding detector module to a preset position to form at least one detector ring in the detection hole, and each detector ring is surrounded by at least part of the multiple detector modules.

[0008] Therefore, the PET detection device according to the embodiment of the present invention has the advantage of being able to easily meet the spatial resolution required for local imaging.

[0009] The PET detection device according to an embodiment of the present invention includes a scanning bed, which includes a bed body and a driving unit. The driving unit can drive the bed body to move into the detection hole so that a subject lying on the bed body is sent into the detection hole. The bed body has a plurality of holes, and the plurality of holes penetrate the bed body along the thickness direction of the bed body. The detector module can extend into the holes to form the detector ring.

[0010] In some embodiments, the length direction of the scanning bed and the axial direction of the detection hole are both the first direction, the width direction of the scanning bed is the second direction, and any two of the first direction, the second direction and the up-down direction are perpendicular to each other;

[0011] The bed body is provided with a first row of holes, a second row of holes and a third row of holes in sequence in the first direction, the first row of holes includes two head and neck holes spaced apart in the second direction, the second row of holes includes two trunk holes spaced apart in the second direction, the third row of holes includes a leg hole, the leg hole is located between the two head and neck holes in the second direction, and the leg hole is located between the two trunk holes in the second direction.

[0012] In some embodiments, the moving part includes a plurality of mechanical arms, each of which is connected to at least one of the detector modules. The mechanical arm can drive the detector module connected thereto to move within the detection hole so as to adjust the position and orientation of the detector module.

[0013] In some embodiments, the inner side surface of the frame includes a first inner side surface, a second inner side surface, a third inner side surface and a fourth inner side surface, the first inner side surface, the second inner side surface, the third inner side surface and the fourth inner side surface define a rectangular detection hole, the first inner side surface and the third inner side surface are perpendicular to the up and down directions, the first inner side surface and the third inner side surface are relatively arranged in the up and down directions, the first inner side surface faces the lower side, the third inner side surface faces the upper side, the second inner side surface and the fourth inner side surface are relatively arranged in the second direction, the second inner side surface and the fourth inner side surface are perpendicular to the second direction, and a plurality of the robotic arms are provided on each of the first inner side surface, the second inner side surface, the third inner side surface and the fourth inner side surface.

[0014] In some embodiments, a plurality of first grooves arranged in a matrix are provided on the first inner side surface, the openings of the first grooves face downward, the first grooves extend in the up-down direction, a mechanical arm is provided in each of the first grooves, a plurality of first drivers are provided in the rack, each of the first drivers is connected to a mechanical arm, and the first driver can drive the mechanical arm connected thereto to extend out of the first groove;

[0015] The second inner side surface is provided with a plurality of second grooves arranged in a matrix, the openings of the second grooves face the fourth inner side surface, the second grooves extend along the second direction, each of the second grooves is provided with a mechanical arm, the rack is provided with a plurality of second drivers, each of the second drivers is connected to a mechanical arm, and the second driver can drive the mechanical arm connected thereto to extend out of the second groove;

[0016] The third inner side surface is provided with a plurality of third grooves arranged in a matrix, the openings of the third grooves are facing upward, the third grooves extend in the up-down direction, each of the third grooves is provided with a mechanical arm, the rack is provided with a plurality of third drivers, each of the third drivers is connected to a mechanical arm, and the third driver can drive the mechanical arm connected thereto to extend out of the third groove;

[0017] The fourth inner side surface is provided with a plurality of fourth grooves arranged in a matrix, the openings of the fourth grooves face the second inner side surface, the fourth grooves extend along the second direction, each of the fourth grooves is provided with a robotic arm, the rack has a plurality of fourth drivers, each of the fourth drivers is connected to a robotic arm, and the fourth driver can drive the robotic arm connected thereto to extend out of the fourth groove.

[0018] In some embodiments, the mechanical arm includes a first connecting rod, a second connecting rod and an actuator, the first connecting rod is connected to the frame, the second connecting rod can rotate relative to the first connecting rod, the actuator can rotate relative to the second connecting rod, and the detector module is arranged on the actuator;

[0019] The driving part includes a fifth driver, a base and a telescopic part, wherein the fifth driver can drive the base to move along the first direction, the telescopic part is arranged on the base, the telescopic part is connected to the bed body and can drive the bed body to move in the up and down directions;

[0020] The detector ring is a circular ring body or an elliptical ring body;

[0021] Each of the detector rings includes a group of detector module sub-rings, and each of the detector module sub-rings includes a plurality of the detector modules spaced apart in the circumferential direction;

[0022] Alternatively, each of the detector rings includes a plurality of groups of detector module sub-rings, each of the detector module sub-rings includes a plurality of detector modules spaced apart in the circumferential direction, and the plurality of groups of detector module sub-rings are arranged sequentially in the first direction.

[0023] The present invention also proposes a PET system, comprising a detector control unit and the above-mentioned PET detection device, wherein the PET detection device is connected to the detector control unit.

[0024] The present invention also proposes a PET detection method using the above-mentioned PET detector, comprising the following steps:

[0025] The subject lying on the bed of the scanning bed is placed into the detection hole of the frame;

[0026] Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring around the entire body of the subject;

[0027] And / or, the corresponding detector module is moved to a preset position by using the moving part on the frame, so as to form a detector ring around the local body area of ​​the subject.

[0028] In some embodiments, the bed body is provided with a first row of holes, a second row of holes and a third row of holes in sequence in the first direction, the first row of holes includes two head and neck holes spaced apart in the second direction, the second row of holes includes two trunk holes spaced apart in the second direction, the third row of holes includes a leg hole, the leg hole is located between the two head and neck holes in the second direction, and the leg hole is located between the two trunk holes in the second direction;

[0029] Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring that penetrates the two head and neck holes and surrounds the head and neck of the subject;

[0030] Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring that penetrates the two trunk holes and surrounds the trunk of the subject;

[0031] Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring that penetrates the leg hole and surrounds the leg of the subject;

[0032] The detector rings arranged around multiple local areas of the subject's body may be formed in stages, or may be formed at once. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] Figure 1 Schematic diagram of a PET detection device according to an embodiment of the present invention.

[0034] Figure 2is a rear view of a PET detection device according to an embodiment of the present invention.

[0035] Figure 3 is a schematic diagram of a moving part according to an embodiment of the present invention.

[0036] Figure 4 is a schematic diagram of a scanning bed according to an embodiment of the present invention.

[0037] Figure 5 is a top view of a scanning bed according to an embodiment of the present invention.

[0038] Figure 6 4 is a schematic diagram of a detector ring of a PET detection device according to an embodiment of the present invention.

[0039] Figure 7 FIG. 4 is another schematic diagram of a detector ring of a PET detection device according to an embodiment of the present invention.

[0040] Figure 8 FIG. 4 is another schematic diagram of a detector ring of a PET detection device according to an embodiment of the present invention.

[0041] Fig. 9 is a schematic diagram of a robotic arm according to an embodiment of the present invention.

[0042] Reference numerals:

[0043] 1. frame, 11. detection hole, 12. first inner side surface, 13. second inner side surface, 131. second groove, 14. third inner side surface, 141. third groove, 15. fourth inner side surface;

[0044] 2. Robotic arm, 21. First connecting rod, 22. Second connecting rod, 23. Actuator;

[0045] 3. Detector module;

[0046] 4. scanning bed, 41. bed body, 42. first row of holes, 421. head and neck holes, 43. second row of holes, 431. trunk holes, 44. third row of holes, 441. leg holes, 45. base, 46. telescopic part;

[0047] 5. Detector ring. DETAILED DESCRIPTION

[0048] Embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and intended to be used to explain the present invention, but should not be understood as limiting the present invention.

[0049] The following describes a PET (positron emission tomography) detection device according to an embodiment of the present invention with reference to the accompanying drawings. Figures 1 to 9As shown, the PET detection device according to the embodiment of the present invention includes a rack 1 and a plurality of detector modules 3 .

[0050] The frame 1 has a detection hole 11 passing through it, and a moving part that can extend into the detection hole 11 is provided in the frame 1. A plurality of detector modules 3 are provided on the moving part, and the moving part can drive each detector module 3 to move in the detection hole 11. The moving part moves the corresponding detector module 3 to a preset position so as to form at least one detector ring 5 in the detection hole 11, and each detector ring 5 is surrounded by at least part of the plurality of detector modules 3.

[0051] The PET detection device according to the embodiment of the present invention is provided with a moving part in the frame 1 that can drive each detector module 3 to move in the detection hole 11, so that the position of each of the multiple detector modules 3 can be moved, and then the position and hole radius of the detector ring 5 of the PET detection device according to the embodiment of the present invention can be adjusted. So that when the staff detects different positions of the subject, the moving part moves part or all of the multiple detector modules 3, so that after the position and the size of the ring radius of the detector ring 5 newly surrounded by the moved detector modules 3 are adjusted, the newly formed detector ring 5 is suitable for detecting the subject. In particular, when detecting a local area of ​​the subject's body, the moving part moves part of the multiple detector modules 3 to form a new detector ring 5 with a smaller ring radius located in the local area of ​​the body, so that the scanning sensitivity of the PET detection device is higher, so as to meet the spatial resolution required for local imaging.

[0052] Therefore, the PET detection device according to the embodiment of the present invention has the advantage of being able to easily meet the spatial resolution required for local imaging.

[0053] like Figures 1 to 5 As shown, in some embodiments, the PET detection device includes a scanning bed 4.

[0054] The scanning bed 4 includes a bed body 41 and a driving unit, and the driving unit can drive the bed body 41 to move into the detection hole 11 so that the subject lies on the bed body 41 and is sent into the detection hole 11. The bed body 41 has a plurality of holes, and the plurality of holes penetrate the bed body 41 along the thickness direction of the bed body 41. Specifically, the thickness direction of the bed body 41 is the up-down direction, and the bed body 41 has a plurality of holes penetrating it along the up-down direction. The length direction of the scanning bed 4 and the axial direction of the detection hole 11 are both the first direction, and the detection hole 11 is open on both sides of the first direction, and the driving unit can drive the bed body 41 to move in the up-down direction and the first direction. The width direction of the scanning bed 4 is the second direction, and any two of the first direction, the second direction and the up-down direction are perpendicular to each other. The first direction can be the front-to-back direction, and the second direction can be the left-to-right direction. The up-to-down direction, the front-to-back direction, and the left-to-right direction are shown by the arrows in the figure. For example, the length direction of the scanning bed 4 and the axial direction of the detection hole 11 are both the front-to-back direction, the detection hole 11 is open on both sides of the front-to-back direction, the driving unit can drive the bed body 41 to move in the up-down direction and the front-to-back direction, and the width direction of the scanning bed 4 is the left-to-right direction.

[0055] In some embodiments, the driving unit includes a fifth driver, a base 45, and a telescopic unit 46. The fifth driver can drive the base 45 to move in the first direction, so that the bed 41 can move into the detection hole 11 in the first direction. The telescopic unit 46 is provided on the base 45, and the telescopic unit 46 is connected to the bed 41 and can drive the bed 41 to move in the up-down direction, so that the bed 41 can be located in a suitable detection position in the up-down direction. For example, the fifth driver is a motor.

[0056] The detector modules 3 can be extended into the holes to form a detector ring 5. Specifically, when the moving part moves a plurality of detector modules 3, a part of the detector modules 3 can be extended into the corresponding holes, so that when imaging a part, the newly formed detector ring 5 can pass through the holes on the bed 41 and be arranged around the body part of the subject, that is, it is not necessary to be arranged around the entire circumference of the entire bed 41, thereby reducing the hole radius of the newly formed detector ring 5.

[0057] In some embodiments, the detector ring 5 is a circular ring or an elliptical ring. For example, the detector ring 5 is a circular ring.

[0058] In some embodiments, each detector ring 5 includes a group of detector module sub-rings, and each detector module sub-ring includes a plurality of detector modules 3 spaced apart in the circumferential direction. Alternatively, each detector ring 5 includes multiple groups of detector module sub-rings, and each detector module sub-ring includes multiple detector modules 3 spaced apart in the circumferential direction, and multiple groups of detector module sub-rings are arranged in sequence in the first direction. Specifically, the shape and size of the detector ring 5 are related to the detection position of the subject. When detecting the entire body of the subject, the detector ring 5 has a larger ring radius and is arranged on the circumferential side of the bed 41, and each detector ring 5 includes multiple groups of detector module sub-rings so as to have sufficient size in the first direction. When detecting a part of the subject, the detector ring 5 has a smaller ring radius and is arranged on the circumferential side of the body part, and each detector ring 5 includes one or more groups of detector module sub-rings.

[0059] like Figure 4 and Figure 5 As shown, in some embodiments, the bed body 41 is provided with a first row of holes 42 , a second row of holes 43 and a third row of holes 44 in sequence in the first direction.

[0060] The first row of holes 42 includes two head and neck holes 421 spaced apart in the second direction, the second row of holes 43 includes two trunk holes 431 spaced apart in the second direction, and the third row of holes 44 includes a leg hole 441, the leg hole 441 is located between the two head and neck holes 421 in the second direction, and the leg hole 441 is located between the two trunk holes 431 in the second direction. Specifically, the first row of holes 42, the second row of holes 43, and the third row of holes 44 are arranged according to the position of the human body's trunk. When the subject lies on the bed 41, the two head and neck holes 421 spaced apart in the second direction may be located on both sides of the human head and neck in the second direction, the two trunk holes 431 spaced apart in the second direction may be located on both sides of the trunk (chest and abdomen) in the second direction, and the leg hole 441 may be located between the two legs of the human body in the second direction.

[0061] Therefore, when detecting the head and neck of a human body, the detector ring 5 can pass through the two head and neck holes 421 and be arranged around the head and neck (such as Figure 6 When detecting the human body's trunk, the detector ring 5 can pass through the two trunk holes 431 and be arranged around the trunk (as shown in FIG. Figure 7 When detecting a leg of a human body, the detector ring 5 can pass through the leg hole 441 and be arranged around the side of the leg (as shown in FIG. Figure 8 As shown in FIG. 4 ). Five holes are provided in three areas of the bed 41, respectively on the left and right sides of the head and neck, the left and right sides of the trunk, and the middle of the legs when the subject lies flat. By providing holes on the bed 41, the detector module 3 is allowed to pass through the bed 41 under the control of the robot arm 2 to form a detector ring structure, thereby realizing imaging of specific parts.

[0062] like Figure 3 As shown, in some embodiments, the moving part includes a plurality of mechanical arms 2, each mechanical arm 2 is connected to at least one detector module 3, and the mechanical arm 2 can drive the detector module 3 connected thereto to move in the detection hole 11 so as to adjust the position and orientation of the detector module 3. Specifically, each mechanical arm 2 can move one or more detector modules 3, thereby facilitating the formation of a new detector ring 5. For example, the mechanical arm 2 is a two-axis mechanical arm, a three-axis mechanical arm, a four-axis mechanical arm, a five-axis mechanical arm, or a six-axis mechanical arm.

[0063] like Fig. 9 As shown, the mechanical arm 2 includes a first connecting rod 21, a second connecting rod 22 and an actuator 23. The first connecting rod 21 is connected to the frame 1, the second connecting rod 22 can rotate relative to the first connecting rod 21, the actuator 23 can rotate relative to the second connecting rod 22, and the detector module 3 is arranged on the actuator 23. Specifically. The first connecting rod 21 is connected to the frame 1 through a moving pair and allows the first connecting rod 21 to slide relative to the frame 1, so as to drive the mechanical arm 2 to move in a straight line. The first connecting rod 21 and the second connecting rod 22 are connected by a rotating pair, and the second connecting rod 22 and the actuator 23 are connected by a rotating pair, so that the detector module 3 can rotate. The mechanical arm 2 is composed of a double connecting rod, including a moving pair and two rotating pairs, forming a planar connecting rod structure, which can realize radial extension and in-plane angle adjustment. The two connecting rods (the first connecting rod 21 and the second connecting rod 22) are combined by a slide rail, and the connecting rod extension and retraction can be realized by a motor. The actuator 23 at the end of each mechanical arm is equipped with a detector module 3, which is composed of a plurality of photoelectric devices and scintillation crystals, wherein the photoelectric devices may be photomultiplier tubes, photodiodes, silicon photomultiplier tubes, etc. The scintillation crystal may be at least one of BGO (bismuth germanate), LSO (lutetium silicate), NaI (sodium iodide), LYSO (cerium-doped lutetium yttrium silicate), LaBr3 (lanthanum bromide), GSO (gadolinium silicate), LGSO (lutetium gadolinium silicate), and GACC (gadolinium aluminum calcium ore). For example, the first connecting rod 21 is slidably connected to the frame 1 through a slide rail.

[0064] In some embodiments, the inner side of the frame 1 includes a first inner side 12 , a second inner side 13 , a third inner side 14 and a fourth inner side 15 , and the first inner side 12 , the second inner side 13 , the third inner side 14 and the fourth inner side 15 define a rectangular detection hole 11 .

[0065] like Figure 1 and Figure 2As shown, the first inner side surface 12 and the third inner side surface 14 are perpendicular to the up-down direction, and the first inner side surface 12 and the third inner side surface 14 are arranged opposite to each other in the up-down direction, the first inner side surface 12 faces the lower side, and the third inner side surface 14 faces the upper side. The second inner side surface 13 and the fourth inner side surface 15 are arranged opposite to each other in the second direction, and the second inner side surface 13 and the fourth inner side surface 15 are perpendicular to the second direction, and a plurality of robot arms 2 are arranged on each of the first inner side surface 12, the second inner side surface 13, the third inner side surface 14, and the fourth inner side surface 15. For example, the second inner side surface 13 faces the right side, and the fourth inner side surface 15 faces the left side.

[0066] In some embodiments, a plurality of first grooves arranged in a matrix are provided on the first inner side surface 12, the opening of the first groove faces the lower side, and the first groove extends in the up-down direction. A mechanical arm 2 is provided in each first groove, and a plurality of first drivers are provided in the rack 1, each first driver is connected to a mechanical arm 2, and the first driver can drive the mechanical arm 2 connected thereto to extend out of the first groove. Specifically, a plurality of mechanical arms 2 arranged in a matrix are installed in the first inner side surface 12, and the first driver can drive the corresponding mechanical arm 2 to move downward so that the detector module 3 on the mechanical arm 2 moves downward. For example, the first driver can drive the (first connecting rod 21) of the mechanical arm 2 connected thereto to move in the up-down direction.

[0067] The second inner side surface 13 is provided with a plurality of second grooves 131 arranged in a matrix, the opening of the second grooves 131 faces the fourth inner side surface 15, and the second grooves 131 extend along the second direction. A mechanical arm 2 is arranged in each second groove 131, and a plurality of second drivers are installed in the rack 1, each second driver is connected to a mechanical arm 2, and the second driver can drive the mechanical arm 2 connected thereto to extend out of the second groove 131. Specifically, a plurality of mechanical arms 2 arranged in a matrix are installed in the second inner side surface 13, and the second driver can drive the corresponding mechanical arm 2 to move toward the fourth inner side surface 15 in the second direction, so that the detector module 3 on the mechanical arm 2 moves toward the fourth inner side surface 15 in the second direction. For example, the second driver can drive the (first connecting rod 21) of the mechanical arm 2 connected thereto to move in the left-right direction.

[0068] The third inner side surface 14 is provided with a plurality of third grooves 141 arranged in a matrix, the opening of the third grooves 141 faces upward, the third grooves 141 extend in the up-down direction, a mechanical arm 2 is provided in each third groove 141, and a plurality of third drivers are provided in the rack 1, each third driver is connected to a mechanical arm 2, and the third driver can drive the mechanical arm 2 connected thereto to extend out of the third groove 141. Specifically, a plurality of mechanical arms 2 arranged in a matrix are installed in the third inner side surface 14, and the third driver can drive the corresponding mechanical arm 2 to move upward, so that the detector module 3 on the mechanical arm 2 moves upward. For example, the third driver can drive the (first connecting rod 21) of the mechanical arm 2 connected thereto to move in the up-down direction.

[0069] The fourth inner side surface 15 is provided with a plurality of fourth grooves arranged in a matrix, the opening of the fourth groove faces the second inner side surface 13, and the fourth groove extends along the second direction. A mechanical arm 2 is provided in each fourth groove, and a plurality of fourth drivers are provided in the rack 1, each of which is connected to a mechanical arm 2, and the fourth driver can drive the mechanical arm 2 connected thereto to extend out of the fourth groove. Specifically, a plurality of mechanical arms 2 arranged in a matrix are installed in the fourth inner side surface 15, and the fourth driver can drive the corresponding mechanical arm 2 to move toward the second inner side surface 13 in the second direction, so that the detector module 3 on the mechanical arm 2 moves toward the second inner side surface 13 in the second direction. For example, the fourth driver can drive the (first connecting rod 21) of the mechanical arm 2 connected thereto to move in the left-right direction.

[0070] The present invention also proposes a PET system. The PET system according to an embodiment of the present invention includes a detector control unit and a PET detection device according to an embodiment of the present invention. The PET detection device according to an embodiment of the present invention is connected to the detector control unit. Specifically, the detector control unit can control the PET detection device so that when detecting the body or a part of the body, the detector control unit can control the position and hole radius of the detector ring 5 formed by the PET detection device to form a detector ring 5 suitable for detection. And the open ring structure PET detection device can dynamically adjust the position, size and shape of the detector ring according to different subjects, and adjust the detector module according to the differences in the subject's body shape, position on the detector bed, and body shape, to form a circular ring detector or an elliptical detector with different radius sizes, so as to optimize the imaging plan for each subject.

[0071] Therefore, the PET system according to the embodiment of the present invention has the advantage of being able to easily satisfy the spatial resolution required for local imaging.

[0072] The present invention further proposes a PET detection method using the PET detection device according to an embodiment of the present invention. The PET detection method according to the embodiment of the present invention comprises the following steps:

[0073] The subject lying on the bed 41 of the scanning bed 4 is put into the detection hole 11 of the rack 1 .

[0074] The corresponding detector module 3 is moved to a preset position by using the moving part on the frame 1, so as to form a detector ring 5 around the entire body of the subject. And / or, the corresponding detector module 3 is moved to a preset position by using the moving part on the frame 1, so as to form a detector ring 5 around a local area of ​​the body of the subject.

[0075] Using the moving part on the rack 1 to move the corresponding detector module 3 to a preset position so as to form a detector ring 5 around the entire body of the subject; and / or using the moving part on the rack 1 to move the corresponding detector module 3 to a preset position so as to form a detector ring 5 around a local area of ​​the body of the subject includes:

[0076] a. Using the moving part on the frame 1 to move the corresponding detector module 3 to a preset position, so as to form a detector ring 5 around the entire body of the subject, that is, to form a detector ring 5 with a larger hole radius around the entire body of the subject, so as to detect the entire body of the subject;

[0077] b. Using the moving part on the frame 1 to move the corresponding detector module 3 to a preset position, so as to form a detector ring 5 around the local area of ​​the subject's body, that is, to form a detector ring 5 with a smaller hole radius around the local area of ​​the subject's body, so as to detect the local area of ​​the subject's body;

[0078] c. Use the moving part on the rack 1 to move the corresponding detector module 3 to a preset position so as to form a detector ring 5 around the entire body of the subject. Use the moving part on the rack 1 to move the corresponding detector module 3 to a preset position so as to form a detector ring 5 around the local body area of ​​the subject. That is, a detector ring 5 with a larger hole radius is formed around the entire body of the subject, and a detector ring 5 is formed around the local body area of ​​the subject, so that the spatial resolution of the body detection is higher at the same time. For example, a detector ring 5 can be formed around the entire body of the subject first, and then a detector ring 5 can be formed around the local body area of ​​the subject.

[0079] Therefore, the PET detection method according to the embodiment of the present invention has the advantage of being able to easily meet the spatial resolution required for local imaging.

[0080] like Figure 6 As shown, in some embodiments, the corresponding detector module 3 is moved to a preset position by using a moving part on the frame 1 to form a detector ring 5 that penetrates the two head and neck holes 421 and is arranged around the head and neck of the subject.

[0081] like Figure 7 As shown, in some embodiments, the corresponding detector module 3 is moved to a preset position by using a moving part on the frame 1 to form a detector ring 5 that penetrates the two trunk holes 431 and is arranged around the trunk of the subject.

[0082] like Figure 8 As shown, in some embodiments, the corresponding detector module 3 is moved to a preset position using a moving part on the frame 1 to form a detector ring 5 that passes through the leg hole 441 and is arranged around the side of the subject's (one) leg.

[0083] The detector rings 5 ​​arranged around multiple local areas of the subject's body can be formed in batches, or the detector rings 5 ​​arranged around multiple local areas of the subject's body can be formed at once. That is, the detector rings 5 ​​arranged around the subject's head and neck, the subject's trunk, and the subject's (one) leg can be formed separately, or multiple detector rings 5 ​​arranged around the subject's head and neck, the subject's trunk, and the subject's (one) leg can be formed simultaneously.

[0084] The PET detection device according to the embodiment of the present invention can realize high-resolution PET imaging of different parts including the whole body, head and neck, chest cavity and joints in the same device. Compared with the whole body PET device in the related art, when imaging a part, the radius of the detector ring 5 is reduced by telescoping the mechanical arm 2 equipped with the detector module 3, which greatly improves the sensitivity of the device, thereby achieving the resolution of a dedicated PET device for a specific area. The open ring structure PET device proposed in this patent can effectively reduce the demand for dedicated PET equipment, reduce the cost of purchasing equipment for hospitals, and eliminate the need for multiple dedicated PET devices for specific areas. Therefore, it also saves hospital space resources.

[0085] In the description of the present invention, it is to be understood that the terms “center”, “longitudinal”, “lateral”, “length”, “width”, “thickness”, “up”, “down”, “front”, “back”, “left”, “right”, “vertical”, “horizontal”, “top”, “bottom”, “inside”, “outside”, “clockwise”, “counterclockwise”, “axial”, “radial”, “circumferential”, etc., indicating orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0086] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0087] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0088] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0089] In the present invention, the terms "one embodiment", "some embodiments", "examples", "specific examples", or "some examples" etc. mean that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the described specific features, structures, materials or characteristics may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0090] Although the embodiments of the present invention have been shown and described above, it is to be understood that the above embodiments are exemplary and are not to be construed as limitations of the present invention. A person skilled in the art may change, modify, replace and vary the above embodiments within the scope of the present invention.

Claims

1. A PET detection device, characterized in that: include: A frame, wherein the frame has a detection hole extending therethrough, and a movable portion is disposed in the frame and can extend into the detection hole; Multiple detector modules are arranged on the moving part, and the moving part can drive each detector module to move in the detection hole. The moving part moves the corresponding detector module to a preset position to form at least one detector ring in the detection hole, and each detector ring is surrounded by at least part of the multiple detector modules.

2. The PET detection device according to claim 1, characterized in that: The scanning bed includes a bed body and a driving unit. The driving unit can drive the bed body to move into the detection hole so that a subject lying on the bed body is sent into the detection hole. The bed body has a plurality of holes, and the plurality of holes penetrate the bed body along the thickness direction of the bed body. The detector module can extend into the holes to form the detector ring.

3. The PET detection device according to claim 2, characterized in that: The length direction of the scanning bed and the axial direction of the detection hole are both the first direction, the width direction of the scanning bed is the second direction, and any two of the first direction, the second direction and the up-down direction are perpendicular to each other; The bed body is provided with a first row of holes, a second row of holes and a third row of holes in sequence in the first direction, the first row of holes includes two head and neck holes spaced apart in the second direction, the second row of holes includes two trunk holes spaced apart in the second direction, the third row of holes includes a leg hole, the leg hole is located between the two head and neck holes in the second direction, and the leg hole is located between the two trunk holes in the second direction.

4. The PET detection device according to claim 3, characterized in that: The moving part includes a plurality of mechanical arms, each of which is connected to at least one of the detector modules. The mechanical arm can drive the detector module connected thereto to move within the detection hole so as to adjust the position and orientation of the detector module.

5. The PET detection device according to claim 4, characterized in that: The inner side surface of the frame includes a first inner side surface, a second inner side surface, a third inner side surface and a fourth inner side surface, the first inner side surface, the second inner side surface, the third inner side surface and the fourth inner side surface define a rectangular detection hole, the first inner side surface and the third inner side surface are perpendicular to the up-down direction, the first inner side surface and the third inner side surface are arranged opposite to each other in the up-down direction, the first inner side surface faces the lower side, the third inner side surface faces the upper side, the second inner side surface and the fourth inner side surface are arranged opposite to each other in the second direction, the second inner side surface and the fourth inner side surface are perpendicular to the second direction, and a plurality of the robotic arms are arranged on each of the first inner side surface, the second inner side surface, the third inner side surface and the fourth inner side surface.

6. The PET detection device according to claim 5, characterized in that: The first inner side surface is provided with a plurality of first grooves arranged in a matrix, the openings of the first grooves are facing downward, the first grooves extend in the up-down direction, each of the first grooves is provided with a mechanical arm, the rack is provided with a plurality of first drivers, each of the first drivers is connected to a mechanical arm, and the first driver can drive the mechanical arm connected thereto to extend out of the first groove; The second inner side surface is provided with a plurality of second grooves arranged in a matrix, the openings of the second grooves face the fourth inner side surface, the second grooves extend along the second direction, each of the second grooves is provided with a mechanical arm, the rack is provided with a plurality of second drivers, each of the second drivers is connected to a mechanical arm, and the second driver can drive the mechanical arm connected thereto to extend out of the second groove; The third inner side surface is provided with a plurality of third grooves arranged in a matrix, the openings of the third grooves are facing upward, the third grooves extend in the up-down direction, each of the third grooves is provided with a mechanical arm, the rack is provided with a plurality of third drivers, each of the third drivers is connected to a mechanical arm, and the third driver can drive the mechanical arm connected thereto to extend out of the third groove; The fourth inner side surface is provided with a plurality of fourth grooves arranged in a matrix, the openings of the fourth grooves face the second inner side surface, the fourth grooves extend along the second direction, each of the fourth grooves is provided with a robotic arm, the rack has a plurality of fourth drivers, each of the fourth drivers is connected to a robotic arm, and the fourth driver can drive the robotic arm connected thereto to extend out of the fourth groove.

7. The PET detection device according to any one of claims 4 to 6, characterized in that: The mechanical arm comprises a first connecting rod, a second connecting rod and an actuator, the first connecting rod is connected to the frame, the second connecting rod can rotate relative to the first connecting rod, the actuator can rotate relative to the second connecting rod, and the detector module is arranged on the actuator; The driving part includes a fifth driver, a base and a telescopic part, wherein the fifth driver can drive the base to move along the first direction, the telescopic part is arranged on the base, the telescopic part is connected to the bed body and can drive the bed body to move in the up and down directions; The detector ring is a circular ring body or an elliptical ring body; Each of the detector rings includes a group of detector module sub-rings, and each of the detector module sub-rings includes a plurality of the detector modules spaced apart in the circumferential direction; Alternatively, each of the detector rings includes a plurality of groups of detector module sub-rings, each of the detector module sub-rings includes a plurality of detector modules spaced apart in the circumferential direction, and the plurality of groups of detector module sub-rings are arranged sequentially in the first direction.

8. A PET system, characterized in that: It comprises a detector control unit and the PET detection device according to any one of claims 1 to 7, wherein the PET detection device is connected to the detector control unit.

9. A PET detection method using the PET detector according to any one of claims 2 to 7, characterized in that: The following steps are involved: The subject lying on the bed of the scanning bed is placed into the detection hole of the frame; Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring around the entire body of the subject; And / or, the corresponding detector module is moved to a preset position by using the moving part on the frame, so as to form a detector ring around the local body area of ​​the subject.

10. The PET detection device according to claim 9, characterized in that: The bed body is provided with a first row of holes, a second row of holes and a third row of holes in sequence in the first direction, the first row of holes includes two head and neck holes spaced apart in the second direction, the second row of holes includes two trunk holes spaced apart in the second direction, the third row of holes includes a leg hole, the leg hole is located between the two head and neck holes in the second direction, and the leg hole is located between the two trunk holes in the second direction; Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring that penetrates the two head and neck holes and surrounds the head and neck of the subject; Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring that penetrates the two trunk holes and surrounds the trunk of the subject; Using the moving part on the frame to move the corresponding detector module to a preset position, so as to form a detector ring that penetrates the leg hole and surrounds the leg of the subject; The detector rings arranged around multiple local areas of the subject's body may be formed in stages, or may be formed at once.