A low-temperature transport and storage device for stem cells

By designing a low-temperature transport and storage device for stem cells, including storage and transportation mechanisms, buffering mechanisms and protective mechanisms, the cell damage caused by sliding and falling of the low-temperature storage and transportation box during stem cell transportation is solved, and the stable fixation of the test tube and buffering and protection of the box are achieved, thereby improving the survival rate of stem cells.

CN119218555BActive Publication Date: 2025-05-13SHANDONG ZHONGRUIYUAN BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411780467.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-12-05
Publication Date
2025-05-13
Estimated Expiration
2044-12-05

AI Technical Summary

Technical Problem

During long-distance stem cell transportation, the surface of the low-temperature storage and transportation box is slippery and makes it difficult to carry, which easily falls off, and thus damages stem cells.

Method used

A stem cell low-temperature transportation storage and transportation device is designed, including storage and transportation mechanism, buffer mechanism and protective mechanism. The storage and transportation mechanism ensures the stable and fixed test tubes through the combination of sealing plates, placement plates and clamping blocks; the buffering mechanism uses hydraulic oil and spring return rods to absorb vibrations of the box; the protection mechanism reduces the rolling and vibration of the box when it falls through protective airbags and inclined connection blocks.

Benefits of technology

It effectively prevents damage to stem cell test tubes during transportation. By evenly distributing impact force and reducing vibration, the survival rate of stem cells is improved, and the risk of further damage to the test tubes is reduced when it falls.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to the technical field of stem cell transportation, and discloses a low-temperature transportation storage and transportation device for stem cells, comprising a storage and transportation mechanism, wherein the storage and transportation mechanism also comprises a box body, the top of the box body is rotatably connected with a sealing plate, and the inner wall of the box body is slidably connected with two placement plates. When the box body falls during transportation, since a counterweight block 1 is installed on the right side of the box body, the right side of the box body is heavier, and the heavier side will contact the ground first, so the contact plate on the right side will contact the ground first, so that the contact plate is squeezed and moves upward, driving a push rod to move, pushing the right side of the placement plate at the bottom to move, allowing the placement plate at the bottom to rotate, and allowing the placement plate to change from an inclined state to a horizontal state, thereby driving the test tube to become a horizontal state, so that the impact force on the test tube can be evenly distributed, reducing damage to the cells, thereby protecting the cells.
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Description

Technical Field

[0001] The present invention relates to the technical field of stem cell transportation equipment, and in particular to a low-temperature transportation and storage device for stem cells. Background Art

[0002] With the rapid development of social economy, stem cells are cells with the potential for proliferation and differentiation, have the ability to self-renew and replicate, and can produce highly differentiated functional cells. The use of stem cell technology will have immeasurable value in the treatment of diseases such as diabetes, cancer, heart disease, leukemia, Parkinson's disease and Alzheimer's disease.

[0003] When stem cells are transported over long distances, it is often necessary to move the storage boxes containing the stem cells onto transport vehicles. In order to preserve the stem cells, the temperature inside the storage boxes is usually low. The low temperature environment may cause the surface of the storage boxes to be slippery, making it easy for the storage boxes to slide during transportation, and may even cause the storage boxes to fall, damaging the stem cells inside the storage boxes. Summary of the invention

[0004] In order to solve the above technical problems, the present invention provides a low-temperature transportation storage device for stem cells, comprising a storage mechanism, the storage mechanism also comprising a box, the top of the box is rotatably connected to a sealing plate, and the inner wall of the box is slidably connected to two placement plates;

[0005] The buffer mechanism comprises two fixed sleeves 1 fixedly connected to the bottom of the box body, the inner walls of the two fixed sleeves 1 are slidably connected with spring return rods 2, and the bottom of the box body is fixedly connected with four fixed sleeves 2;

[0006] The protection mechanism comprises two fixed frames fixedly connected to the front and back of the box body, the side walls of the two fixed frames at the bottom are fixedly connected with connecting frames, and the outer walls of the two connecting frames are rotatably connected with rotating frames.

[0007] Preferably, the storage and transportation mechanism further comprises a counterweight block fixedly connected to the inner wall of the box body, four fixed plates are fixedly connected to the tops of the two placement plates, a plurality of clamping blocks are slidably connected to the tops of the two placement plates, and a spring return rod is fixedly connected to the side walls of the plurality of clamping blocks;

[0008] Among them, the outer walls of several spring reset rods are slidably connected to the inner wall of the fixed plate, and the inner walls of the two placement plates are slidably connected with test tubes. The staff opens the sealing plate and inserts the test tubes containing stem cells into the holes of the placement plate. During the insertion process, the test tube will squeeze the clamping block, so that the two clamping blocks move away from each other, and at the same time squeeze the spring reset rod 1, so that the spring reset rod 1 accumulates rebound force, and the clamping block clamps the test tube through the rebound force of the spring reset rod 1 until the test tube is clamped by the upper and lower clamping blocks at the same time, and the test tube is fixed. After the test tube is installed, the sealing plate is closed.

[0009] Preferably, the storage and transportation mechanism further comprises two contact plates arranged at the bottom of the box body, a push rod is fixedly connected to the side wall of the right contact plate, the outer wall of the push rod is slidably connected to the inner wall of the box body, and four connecting rods are fixedly connected to the top of the bottom placement plate;

[0010] Among them, sliding sleeves are fixedly connected to the side walls of the two placement plates, and a cold air tank is fixedly connected to the bottom of the inner wall of the box. When the box falls during transportation, since a counterweight block is installed on the right side of the box, the right side of the box is heavier, and the heavier side will contact the ground first. Therefore, the contact plate on the right side will contact the ground first, so that the contact plate is squeezed and moves upward, driving the push rod to move, and pushing the right side of the bottom placement plate to move.

[0011] Preferably, the storage and transportation mechanism also includes four fixing frames arranged on the side walls of the placement plate, the side walls of the two fixing frames on the right are fixedly connected to the side walls of the counterweight block 1, the side walls of the two fixing frames on the left are fixedly connected to the inner wall of the box body, and the inner walls of the four sliding sleeves are slidably connected to the outer walls of the fixing frames, so that the placement plate at the bottom rotates, driving the sliding sleeve on the right to slide in the fixing frame on the right, and the sliding sleeve on the left to rotate in the fixing frame on the left. When the placement plate at the bottom moves, it will also drive the connecting rod to push the connecting rod at the top to move, so that the placement plate at the top rotates, so that the placement plate changes from an inclined state to a horizontal state, thereby driving the test tube to a horizontal state, such as: Figure 6 As shown, by making the placement plate horizontal, the impact force on the test tube can be evenly distributed, reducing damage to the cells. Horizontal placement also prevents the test tube from tilting for a long time, which may cause the cells to settle or aggregate in a certain position, thereby affecting the cell activity, thereby protecting the cells.

[0012] Preferably, the buffer mechanism also includes a connecting rod rotatably connected to the top of the contact plate, the inner walls of the four fixed sleeves are slidably connected with extrusion rods, the side walls of the four extrusion rods are rotatably connected to the inner wall of the connecting rod, and the bottoms of the two spring return rods are fixedly connected to the top of the contact plate. By utilizing the force of the movement of the contact plate, when the contact plate moves upward, the spring return rod 2 will also be driven to move, so that the spring return rod 2 is squeezed. At the same time, when the contact plate moves, it will also drive the connecting rod to move, so that the connecting rod rotates and pushes the extrusion rod away from the fixed sleeve.

[0013] Preferably, the buffer mechanism further comprises a push rod fixedly connected to the side wall of the right extrusion rod, the outer walls of the two push rods are slidably connected to the inner wall of the fixed sleeve 2, the inner walls of the four fixed sleeves 2 are provided with hydraulic oil, the inner walls of the four fixed sleeves 2 are provided with oil delivery grooves, when the extrusion rod moves, the hydraulic oil inside the fixed sleeve 2 is squeezed, and the squeezed hydraulic oil enters the oil delivery groove, and as the extrusion rod continues to move, a gap is left on the right side of the fixed sleeve 2, such as: Figure 8 As shown, the hydraulic oil entering the oil delivery groove can enter the gap on the right side of the extrusion rod, and the vibration of the box body is buffered by the spring return rod 2.

[0014] Preferably, the protection mechanism further comprises an extrusion plate slidably connected to the inner wall of the fixed frame, the side walls of the two extrusion plates are fixedly connected with connecting plates, the side walls of the two connecting plates are slidably connected to the inner wall of the rotating frame, and the inner walls of the two rotating frames are slidably connected to the side walls of the push rod;

[0015] The side walls of the four fixed frames are all connected with gas pipes, and the side walls of the box body are all fixedly connected with four protective air bags. By utilizing the force of the movement of the extrusion rod, the extrusion rod is temporarily away from the fixed sleeve, which also drives the push rod to move, slide on the inner wall of the rotating frame, and push the rotating frame to rotate, so that the rotating frame tilts. When the rotating frame rotates, it will push the connecting plate to move toward the box body. When the connecting plate moves, it will drive the extrusion plate to move, so that the extrusion plate squeezes the gas inside the fixed frame.

[0016] Preferably, the protective mechanism also includes an inclined connecting block fixedly connected to the side wall of the connecting plate, the front and back sides of the box are fixedly connected with telescopic rods, the front and back sides of the box are slidably connected with counterweight blocks 2, the bottoms of the two counterweight blocks 2 are fixedly connected with inclined rods, the bottoms of the two telescopic rods are fixedly connected to the tops of the counterweight blocks 2, and the force of the movement of the connecting plate will also drive the inclined connecting block to move when the connecting plate approaches the box, and the inclined connecting block will contact the contact plate during the movement process. Since the contact surfaces of the inclined connecting block and the inclined rod are both inclined surfaces, the inclined connecting block will smoothly push the inclined rod to rise, thereby driving the counterweight block 2 on the lighter side of the box to rise.

[0017] The present invention has the following beneficial effects:

[0018] (1) When the present invention is used, the staff opens the sealing plate and inserts the test tube containing stem cells into the hole of the placement plate. During the insertion process, the test tube will squeeze the clamping block, causing the two clamping blocks to move away from each other, and at the same time squeeze the spring return rod 1, allowing the spring return rod 1 to accumulate rebound force. Through the rebound force of the spring return rod 1, the clamping block clamps the test tube until the test tube is clamped by the upper and lower clamping blocks at the same time, thereby fixing the test tube. After the test tube is installed, the sealing plate is closed. When the box falls during transportation, since a counterweight block 1 is installed on the right side of the box, the right side of the box is heavier, and the heavier side The right side will contact the ground first, so the contact plate on the right will contact the ground first, so that the contact plate is squeezed and moves upward, driving the push rod to move, pushing the right side of the bottom placement plate to move, allowing the placement plate at the bottom to rotate, driving the sliding sleeve on the right to slide in the right fixed frame, and the sliding sleeve on the left to rotate in the left fixed frame. When the placement plate at the bottom moves, it will also drive the connecting rod to push the connecting rod at the top to move, so that the placement plate at the top rotates, so that the placement plate changes from an inclined state to a horizontal state, thereby driving the test tube to a horizontal state, such as: Figure 6 As shown, by making the placement plate horizontal, the impact force on the test tube can be evenly distributed, reducing damage to the cells. Horizontal placement also prevents the test tube from tilting for a long time, which may cause the cells to settle or aggregate in a certain position, thereby affecting the cell activity, thereby protecting the cells.

[0019] (2) The present invention utilizes the force of the contact plate moving upward, and when the contact plate moves upward, it also drives the spring return rod 2 to move, so that the spring return rod 2 is squeezed. At the same time, when the contact plate moves, it also drives the connecting rod to move, so that the connecting rod rotates and pushes the squeezing rod away from the fixed sleeve 1. When the squeezing rod moves, it squeezes the hydraulic oil inside the fixed sleeve 2, and the squeezed hydraulic oil enters the oil delivery tank. As the squeezing rod continues to move, a gap will be left on the right side of the fixed sleeve 2, such as: Figure 8 As shown, the hydraulic oil entering the oil tank can enter the gap on the right side of the extrusion rod, and the vibration of the box body is buffered by the spring return rod 2. When the rebound force of the spring return rod 2 is released, the contact plate is returned, driving the extrusion rod to return. Since there is hydraulic oil on the right side of the extrusion rod, the extrusion rod will be affected by the resistance of the hydraulic oil when it returns, thereby absorbing the rebound force of the spring return rod 2, preventing the spring return rod 2 from rebounding frequently, causing the push rod to frequently push the placement plate, causing the placement plate to shake, thereby reducing the impact of the vibration on the test tube and improving the survival rate of stem cells.

[0020] (3) The present invention utilizes the force of the extrusion rod moving. When the extrusion rod moves away from the fixed sleeve, it also drives the push rod to move, slide on the inner wall of the rotating frame, and drive the rotating frame to rotate, so that the rotating frame tilts. When the rotating frame rotates, it will push the connecting plate to move toward the box body. When the connecting plate moves, it will drive the extrusion plate to move, so that the extrusion plate squeezes the gas inside the fixed frame. The squeezed gas will enter the protective airbag through the air supply pipe, thereby expanding the protective airbag at the corner of the box body. The supporting effect of the protective airbag at the corner can help the box body remain relatively stable when it falls, reduce the possibility of rolling, and reduce the possibility of further damage to the test tube.

[0021] (4) The present invention utilizes the force of the movement of the connecting plate. When the connecting plate approaches the box, it will also drive the inclined connecting block to move. During the movement process, the inclined connecting block will contact the contact plate. Since the contact surfaces of the inclined connecting block and the inclined rod are both inclined, the inclined connecting block will smoothly push the inclined rod to rise, driving the counterweight block 2 on the lighter side of the box to rise, allowing the telescopic rod to retract. The force generated by the rise of the counterweight block 2 can offset part of the downward gravity, thereby reducing the force on the box when it falls, thereby reducing the vibration of the box, and reducing the risk of damage to the stem cells inside the box. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0023] Figure 1 It is a schematic cross-sectional view of the overall structure of the present invention;

[0024] Figure 2 It is a schematic diagram of the overall structure of the present invention;

[0025] Figure 3 It is a schematic cross-sectional view of the box body of the present invention;

[0026] Figure 4 For the present invention Figure 3 A is an enlarged schematic diagram;

[0027] Figure 5 It is a bottom-view cross-sectional schematic diagram of the box body of the present invention;

[0028] Figure 6 This is a schematic diagram of the work flow of placing a plate according to the present invention;

[0029] Figure 7 It is a cross-sectional schematic diagram of a fixing sleeve of the present invention;

[0030] Figure 8 For the present invention Figure 7 A magnified schematic diagram of B;

[0031] Fig. 9 It is a cross-sectional schematic diagram of a fixing frame of the present invention;

[0032] Fig.10 It is a schematic cross-sectional view of the box body of the present invention from the left.

[0033] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0034] In the figure: 1. storage and transportation mechanism; 101. box; 102. sealing plate; 103. placement plate; 104. counterweight block 1; 105. fixing plate; 106. clamping block; 107. spring return rod 1; 108. test tube; 109. contact plate; 110. push rod; 111. connecting rod; 112. sliding sleeve; 113. fixing frame; 114. cold air tank; 2. buffer mechanism; 201. fixing sleeve 1; 202. spring return rod Spring return rod 2; 203, fixed sleeve 2; 204, connecting rod; 205, extrusion rod; 206, oil tank; 207, push rod; 3, protection mechanism; 301, fixed frame; 302, connecting frame; 303, rotating frame; 304, connecting plate; 305, extrusion plate; 306, air pipe; 307, protective airbag; 308, inclined connecting block; 309, inclined rod; 310, telescopic rod; 311, counterweight block 2. DETAILED DESCRIPTION

[0035] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0036] For example, see Figure 1-Figure 6 The present invention is a low-temperature transport storage device for stem cells, comprising a storage mechanism 1, wherein the storage mechanism 1 further comprises a box 101, a sealing plate 102 is rotatably connected to the top of the box 101, and two placement plates 103 are slidably connected to the inner wall of the box 101;

[0037] The buffer mechanism 2 includes two fixed sleeves 201 fixedly connected to the bottom of the box body 101, the inner walls of the two fixed sleeves 201 are slidably connected with spring return rods 202, and the bottom of the box body 101 is fixedly connected with four fixed sleeves 203;

[0038] The protection mechanism 3 includes two fixed frames 301 fixedly connected to the front and back of the box body 101, the side walls of the two fixed frames 301 at the bottom are fixedly connected to connecting frames 302, and the outer walls of the two connecting frames 302 are rotatably connected to rotating frames 303.

[0039] The storage and transportation mechanism 1 also includes a counterweight block 104 fixedly connected to the inner wall of the box body 101, four fixed plates 105 are fixedly connected to the tops of the two placement plates 103, a plurality of clamping blocks 106 are slidably connected to the tops of the two placement plates 103, and a spring return rod 107 is fixedly connected to the side walls of the plurality of clamping blocks 106;

[0040] Among them, the outer walls of several spring reset rods 107 are slidably connected to the inner wall of the fixed plate 105, and the inner walls of the two placement plates 103 are slidably connected with test tubes 108. The staff opens the sealing plate 102 and inserts the test tube 108 containing stem cells into the hole of the placement plate 103. During the insertion process, the test tube 108 will squeeze the clamping block 106, so that the two clamping blocks 106 move away from each other, and at the same time squeeze the spring reset rod 107, so that the spring reset rod 107 accumulates rebound force, and the clamping block 106 clamps the test tube 108 through the rebound force of the spring reset rod 107 until the test tube 108 is clamped by the upper and lower clamping blocks 106 at the same time, and the test tube 108 is fixed. After the test tube 108 is installed, the sealing plate 102 is closed.

[0041] The storage and transportation mechanism 1 also includes two contact plates 109 arranged at the bottom of the box body 101, a push rod 110 is fixedly connected to the side wall of the right contact plate 109, and the outer wall of the push rod 110 is slidably connected to the inner wall of the box body 101, and four connecting rods 111 are fixedly connected to the top of the bottom placement plate 103;

[0042] Among them, the side walls of the two placement plates 103 are fixedly connected with sliding sleeves 112, and the bottom of the inner wall of the box body 101 is fixedly connected with a cold air tank 114. When the box body 101 falls during transportation, since a counterweight block 104 is installed on the right side of the box body 101, the right side of the box body 101 is heavier, and the heavier side will contact the ground first. Therefore, the contact plate 109 on the right side will contact the ground first, so that the contact plate 109 is squeezed and moves upward, driving the push rod 110 to move, and pushing the right side of the placement plate 103 at the bottom to move.

[0043] The storage and transportation mechanism 1 also includes four fixing frames 113 arranged on the side walls of the placement plate 103. The side walls of the two fixing frames 113 on the right are fixedly connected to the side walls of the counterweight block 104, and the side walls of the two fixing frames 113 on the left are fixedly connected to the inner walls of the box body 101. The inner walls of the four sliding sleeves 112 are slidably connected to the outer walls of the fixing frames 113, so that the placement plate 103 at the bottom rotates, driving the sliding sleeve 112 on the right to slide in the fixing frame 113 on the right, and the sliding sleeve 112 on the left to rotate in the fixing frame 113 on the left. When the placement plate 103 at the bottom moves, it will also drive the connecting rod 111 to push the connecting rod 111 at the top to move, so that the placement plate 103 at the top rotates, so that the placement plate 103 changes from an inclined state to a horizontal state, thereby driving the test tube 108 to a horizontal state, such as: Figure 6 As shown, by making the placement plate 103 horizontal, the impact force on the test tube 108 can be evenly distributed, reducing damage to the cells. The horizontal placement also prevents the test tube 108 from tilting for a long time, causing the cells to precipitate or aggregate in a certain position, thereby affecting the cell activity, thereby protecting the cells.

[0044] For example 2, please refer to Figure 7-10 The present invention is a low-temperature transportation and storage device for stem cells. On the basis of Example 1, the buffer mechanism 2 also includes a connecting rod 204 rotatably connected to the top of the contact plate 109, and the inner walls of the four fixed sleeves 203 are slidably connected with extrusion rods 205. The side walls of the four extrusion rods 205 are rotatably connected to the inner walls of the connecting rod 204. The bottoms of the two spring return rods 202 are fixedly connected to the top of the contact plate 109. By utilizing the force of the movement of the contact plate 109, when the contact plate 109 moves upward, the spring return rod 202 is also driven to move, so that the spring return rod 202 is squeezed. At the same time, when the contact plate 109 moves, the connecting rod 204 is also driven to move, so that the connecting rod 204 rotates and pushes the extrusion rod 205 away from the fixed sleeve 1 201.

[0045] The buffer mechanism 2 also includes a push rod 207 fixedly connected to the side wall of the right extrusion rod 205. The outer walls of the two push rods 207 are slidably connected to the inner wall of the fixed sleeve 203. The inner walls of the four fixed sleeves 203 are provided with hydraulic oil. The inner walls of the four fixed sleeves 203 are provided with oil delivery grooves 206. When the extrusion rod 205 moves, the hydraulic oil inside the fixed sleeve 203 is squeezed, and the squeezed hydraulic oil enters the oil delivery groove 206. As the extrusion rod 205 continues to move, a gap will be left on the right side of the fixed sleeve 203, such as: Figure 8 As shown, the hydraulic oil entering the oil delivery groove 206 can enter the gap on the right side of the extrusion rod 205, and the vibration of the box body 101 is buffered by the spring return rod 202.

[0046] The protection mechanism 3 further includes an extrusion plate 305 slidably connected to the inner wall of the fixed frame 301, and the side walls of the two extrusion plates 305 are fixedly connected with connecting plates 304, and the side walls of the two connecting plates 304 are slidably connected to the inner wall of the rotating frame 303, and the inner walls of the two rotating frames 303 are slidably connected to the side walls of the push rod 207;

[0047] The side walls of the four fixed frames 301 are all connected with air pipes 306, and the side walls of the box body 101 are all fixedly connected with four protective air bags 307. By utilizing the force of the movement of the extrusion rod 205, when the extrusion rod 205 moves away from the fixed sleeve 201, it also drives the push rod 207 to move, slide on the inner wall of the rotating frame 303, and push the rotating frame 303 to rotate, so that the rotating frame 303 is tilted. When the rotating frame 303 rotates, it will push the connecting plate 304 to move toward the box body 101. When the connecting plate 304 moves, it will drive the extrusion plate 305 to move, so that the extrusion plate 305 squeezes the gas inside the fixed frame 301.

[0048] The protection mechanism 3 also includes an inclined connecting block 308 fixedly connected to the side wall of the connecting plate 304, a telescopic rod 310 is fixedly connected to the front and back of the box body 101, and a counterweight block 311 is slidably connected to the front and back of the box body 101, and the bottoms of the two counterweight blocks 311 are fixedly connected to the inclined rod 309, and the bottoms of the two telescopic rods 310 are fixedly connected to the top of the counterweight block 311. By utilizing the force of the movement of the connecting plate 304, when the connecting plate 304 approaches the box body 101, the inclined connecting block 308 will also be driven to move, and the inclined connecting block 308 will contact the contact plate 109 during the movement process. Since the contact surfaces of the inclined connecting block 308 and the inclined rod 309 are both inclined surfaces, the inclined connecting block 308 will smoothly push the inclined rod 309 to rise, thereby driving the counterweight block 311 on the lighter side of the box body 101 to rise.

[0049] There is no limitation on the number of the above components, and relevant technicians in the field can freely set them according to actual needs, as long as the above components are installed at the connection positions of the corresponding components.

[0050] A specific application of this embodiment is as follows: when the present invention is used, the staff opens the sealing plate 102 and inserts the test tube 108 containing stem cells into the hole of the placement plate 103. During the insertion process, the test tube 108 will squeeze the clamping block 106 to move the two clamping blocks 106 away from each other, and at the same time squeeze the spring return rod 107 to allow the spring return rod 107 to accumulate resilience. Through the resilience of the spring return rod 107, the clamping block 106 clamps the test tube 108 until the test tube 108 is clamped by the upper and lower clamping blocks 106 at the same time, thereby fixing the test tube 108. After the test tube 108 is installed, the sealing plate 102 is closed. When the box 101 is transported and dropped, since the counterweight block 104 is installed on the right side of the box 101, the box The right side of 101 is heavier, and the heavier side will contact the ground first, so the contact plate 109 on the right will contact the ground first, so that the contact plate 109 is squeezed and moves upward, driving the push rod 110 to move, pushing the right side of the bottom placement plate 103 to move, allowing the placement plate 103 at the bottom to rotate, driving the sliding sleeve 112 on the right to slide in the fixing frame 113 on the right, and the sliding sleeve 112 on the left to rotate in the fixing frame 113 on the left. When the placement plate 103 at the bottom moves, it will also drive the connecting rod 111 to push the connecting rod 111 at the top to move, so that the placement plate 103 at the top rotates, so that the placement plate 103 changes from an inclined state to a horizontal state, thereby driving the test tube 108 to a horizontal state, such as: Figure 6 As shown, by making the placement plate 103 tend to be horizontal, the impact force on the test tube 108 can be evenly distributed, reducing damage to the cells. The horizontal placement also prevents the test tube 108 from tilting for a long time, causing the cells to precipitate or aggregate in a certain position, thereby affecting the cell activity, thereby protecting the cells.

[0051] The interior of the box 101 is kept at a low temperature by the cold air tank 114;

[0052] When the contact plate 109 moves upward, it also drives the spring return rod 202 to move, so that the spring return rod 202 is squeezed. At the same time, when the contact plate 109 moves, it also drives the connecting rod 204 to move, so that the connecting rod 204 rotates and pushes the squeezing rod 205 away from the fixed sleeve 1 201. When the squeezing rod 205 moves, it squeezes the hydraulic oil inside the fixed sleeve 203, and the squeezed hydraulic oil enters the oil delivery groove 206. As the squeezing rod 205 continues to move, a gap will be left on the right side of the fixed sleeve 203, such as: Figure 8As shown, the hydraulic oil entering the oil delivery groove 206 can enter the gap on the right side of the squeezing rod 205, and the vibration of the box body 101 is buffered by the spring return rod 202. When the rebound force of the spring return rod 202 is released, the contact plate 109 is returned, driving the squeezing rod 205 to return. Since there is hydraulic oil on the right side of the squeezing rod 205, when the squeezing rod 205 returns, it will be affected by the resistance of the hydraulic oil, thereby absorbing the rebound force of the spring return rod 202, preventing the spring return rod 202 from rebounding frequently, causing the push rod 110 to frequently push the placement plate 103, causing the placement plate 103 to shake, thereby reducing the impact of the vibration on the test tube 108 and improving the survival rate of stem cells.

[0053] Secondly, when the squeezing rod 205 moves away from the fixing sleeve 201, it also drives the pushing rod 207 to move, slide on the inner wall of the rotating frame 303, and push the rotating frame 303 to rotate, so that the rotating frame 303 is tilted. When the rotating frame 303 rotates, it will push the connecting plate 304 to move toward the box body 101. When the connecting plate 304 moves, it will drive the squeezing plate 305 to move, so that the squeezing plate 305 squeezes the gas inside the fixing frame 301. The squeezed gas will enter the protective airbag 307 through the gas pipe 306, so that the protective airbag 307 at the corner of the box body 101 will expand. The supporting effect of the protective airbag 307 at the corner can help the box body 101 to remain relatively stable when it falls, reduce the possibility of rolling, and reduce the possibility of further damage to the test tube 108;

[0054] When the connecting plate 304 approaches the box 101, it will also drive the inclined connecting block 308 to move. During the movement, the inclined connecting block 308 will contact the contact plate 109. Since the contact surfaces of the inclined connecting block 308 and the inclined rod 309 are both inclined surfaces, the inclined connecting block 308 will smoothly push the inclined rod 309 to rise, driving the counterweight block 2 311 on the lighter side of the box 101 to rise, allowing the telescopic rod 310 to retract. The force generated by the rise of the counterweight block 2 311 can offset part of the downward gravity, thereby reducing the force on the box 101 when it falls, thereby reducing the vibration of the box 101, and reducing the risk of damage to the stem cells inside the box 101.

[0055] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A low-temperature transport storage device for stem cells, comprising a storage mechanism, wherein the storage mechanism further comprises a box, a sealing plate is rotatably connected to the top of the box, and two placement plates are slidably connected to the inner wall of the box, characterized in that: Also includes: A buffer mechanism, the buffer mechanism comprising two fixed sleeves 1 fixedly connected to the bottom of the box body, the inner walls of the two fixed sleeves 1 are slidably connected with spring return rods 2, and the bottom of the box body is fixedly connected with four fixed sleeves 2; A protection mechanism, the protection mechanism comprising two fixed frames fixedly connected to the front and back of the box body, the side walls of the two fixed frames at the bottom are fixedly connected to connecting frames, and the outer walls of the two connecting frames are rotatably connected to rotating frames; The storage and transportation mechanism also includes a counterweight block fixedly connected to the inner wall of the box body, four fixed plates are fixedly connected to the tops of the two placement plates, a plurality of clamping blocks are slidably connected to the tops of the two placement plates, and a spring return rod is fixedly connected to the side walls of the plurality of clamping blocks; Among them, the outer walls of several of the spring return rods are slidably connected to the inner wall of the fixed plate, and the inner walls of the two placement plates are slidably connected with test tubes; The storage and transportation mechanism also includes two contact plates arranged at the bottom of the box body, a push rod is fixedly connected to the side wall of the contact plate on the right side, the outer wall of the push rod is slidably connected to the inner wall of the box body, and four connecting rods are fixedly connected to the top of the placement plate at the bottom; Wherein, the side walls of the two placement plates are fixedly connected with sliding sleeves, and the bottom of the inner wall of the box body is fixedly connected with a cold air tank; The storage and transportation mechanism also includes four fixed frames arranged on the side walls of the placement plate, the side walls of the two fixed frames on the right side are fixedly connected to the side wall of the counterweight block 1, the side walls of the two fixed frames on the left side are fixedly connected to the inner walls of the box body, and the inner walls of the four sliding sleeves are slidably connected to the outer walls of the fixed frames.

2. A stem cell low-temperature transportation and storage device according to claim 1, characterized in that: The buffer mechanism also includes a connecting rod rotatably connected to the top of the contact plate, the inner walls of the four fixed sleeves are slidably connected with extrusion rods, the side walls of the four extrusion rods are rotatably connected to the inner wall of the connecting rod, and the bottoms of the two spring return rods are fixedly connected to the top of the contact plate.

3. A stem cell low-temperature transport storage device according to claim 2, characterized in that: The buffer mechanism also includes a push rod fixedly connected to the side wall of the right extrusion rod, the outer walls of the two push rods are slidably connected to the inner wall of the fixed sleeve 2, the inner walls of the four fixed sleeves 2 are provided with hydraulic oil, and the inner walls of the four fixed sleeves 2 are provided with oil delivery grooves.

4. The low-temperature transport and storage device for stem cells according to claim 3, characterized in that: The protection mechanism also includes an extrusion plate slidably connected to the inner wall of the fixed frame, the side walls of the two extrusion plates are fixedly connected with connecting plates, the side walls of the two connecting plates are slidably connected to the inner wall of the rotating frame, and the inner walls of the two rotating frames are slidably connected to the side walls of the push rod; The side walls of the four fixed frames are all connected with air delivery pipes, and the side walls of the box body are all fixedly connected with four protective air bags.

5. The low-temperature transport and storage device for stem cells according to claim 4, characterized in that: The protective mechanism also includes an inclined connecting block fixedly connected to the side wall of the connecting plate, the front and back sides of the box body are fixedly connected with telescopic rods, the front and back sides of the box body are slidably connected with counterweight blocks 2, the bottoms of the two counterweight blocks 2 are fixedly connected with inclined rods, and the bottoms of the two telescopic rods are fixedly connected to the top of the counterweight block 2.

Citation Information

Patent Citations

  • Transportation device applied to stem cells

    CN219340167U

  • Multifunctional coaming for turnover box

    CN221091901U