Light-loss-resistant sunscreen gel

Abstract

The invention belongs to the field of daily chemicals, and discloses an anti-light-loss sunscreen gel, which comprises 2.5-3.5 wt% of a polydimethylsiloxane PEG-10 / 15 cross-linked polymer, 0.5-1.5 wt% of an anti-light-loss sunscreen agent, and the balance of water. 0.2 to 0.4 wt% of PEG-10 (Polyethylene Glycol-10) polydimethylsiloxane; 5 to 10 weight percent of polydimethylsiloxane; the sunscreen composition is prepared from a water-soluble sunscreen agent, an oil-soluble sunscreen agent, polyquaternium-61, a solubilizer, an oil-soluble active ingredient and the balance of water. According to the sunscreen gel, an oil-in-water-in-oil system is constructed, oil-soluble active ingredients are wrapped in the innermost layer, the secondary outer layer is a water layer containing a water-soluble sunscreen agent, the outermost layer is a continuous phase containing an oil-soluble sunscreen agent, and due to the design of the two sunscreen layers, the active ingredients in the innermost layer are not prone to fading and losing activity.

Description

Technical Field

[0001] The invention relates to the field of sunscreen products, and in particular to an anti-photodamage sunscreen gel. Background Art

[0002] Most existing sunscreens use chemical sunscreens and / or physical sunscreens for sun protection;

[0003] In the prior art, there are not many technical solutions for sunscreen gel. For example, Chinese patent publication No. CN 116115523 A, the subject is sunscreen gel, which discloses that the following components are included in parts by mass: 16.3 to 27.6 parts of sunscreen agent, 4 to 5 parts of emulsifier, 2 to 10 parts of film former, 8 to 40 parts of moisturizer, 8 to 12 parts of emollient, 20 to 100 parts of solvent, 0.3 to 0.8 parts of neutralizer, and 0.1 to 1 parts of preservative; the technical effect is that a transparent gel can be obtained.

[0004] There are sunscreens in the oil phase of the above products. In subsequent studies, we found that if oil-soluble active ingredients that are easily oxidized and degraded are directly added to the formula, the active ingredients are easily oxidized. The reason is that the active ingredients are easily exposed to ultraviolet rays.

[0005] Therefore, at the beginning of the design, we conceived that if we could construct two sunscreen layers through the above-mentioned oil phase and water phase containing sunscreen, then the degradation of active ingredients such as discoloration could be reduced.

[0006] There are the following difficulties in implementing this plan:

[0007] 1. How to build the envisioned system;

[0008] 2. How to ensure that the constructed system can still maintain a transparent gel state. Summary of the invention

[0009] One of the purposes of the present invention is to provide an anti-photodamage sunscreen gel, which constructs an oil-in-water-in-oil system, wraps the oil-soluble active ingredients in the innermost layer, the second outermost layer is a water layer containing a water-soluble sunscreen agent, and the outermost layer is a continuous phase containing an oil-soluble sunscreen agent. Through the design of two sunscreen layers, the active ingredients in the innermost layer can be prevented from being easily degraded.

[0010] To achieve the above object, the present invention provides an anti-light damage sunscreen gel, comprising:

[0011] PEG-10 / 15 cross-linked polydimethylsiloxane 2.5-3.5 wt%;

[0012] PEG-10 polydimethylsiloxane 0.2-0.4wt%;

[0013] Polydimethylsiloxane 5-10wt%;

[0014] Water-soluble sunscreen, oil-soluble sunscreen, polyquaternium-61, solubilizer, oil-soluble active ingredient;

[0015] The dosage of the polyquaternium salt-61 is 0.002-0.02wt%;

[0016] The solubilizing agent is used in an amount of 0.01 to 0.1 wt %;

[0017] The oil-soluble sunscreen contains ethylhexyl salicylate;

[0018] The amount of ethylhexyl salicylate is not less than 2wt%;

[0019] The remaining amount of water.

[0020] In the above system, polydimethylsiloxane PEG-10 / 15 cross-linked polymer, PEG-10 polydimethylsiloxane, and polydimethylsiloxane are continuous oil phases; the emulsifiers constituting the oil-in-water-in-oil microcapsules are polyquaternium salts and PPG-13-decyltetradecyl alcohol polyether-24; water, water-soluble sunscreen agents, and other water-soluble ingredients that may exist (such as water-soluble active ingredients allowed to be added in the formula) constitute the water phase of the microcapsules; and the oil-soluble active ingredients are the oil phase of the microcapsules.

[0021] Through the above structure, a double sunscreen layer can be constructed through a continuous phase and an aqueous phase to reduce the effect of light on oil-soluble active ingredients.

[0022] In the process of constructing the system, it was further discovered that when an oil-in-water-in-oil emulsion system is used, the following factors will destroy the stability of the system, making the system opaque and / or not in a gel state;

[0023] Factor 1: Selection and dosage of emulsifier polyquaternium-61;

[0024] Factor 2: the amount of ethylhexyl salicylate, an oil-soluble sunscreen ingredient;

[0025] Factor 3: The amount of polydimethylsiloxane used.

[0026] Among them, the choice of emulsifier and the amount of ethylhexyl salicylate used are the main factors, and polydimethylsiloxane is a secondary factor.

[0027] The above factors jointly determine the state of the system.

[0028] In the above-mentioned anti-photodamage sunscreen gel, the solubilizer is one or more combinations of PPG-13-decyltetradecyl alcohol polyether-24, polysorbate-20, and PEG-40 hydrogenated castor oil.

[0029] In the above-mentioned anti-photodamage sunscreen gel, the oil-soluble active ingredient is one or more combinations of astaxanthin, guaiac, lithospermum oil, sea buckthorn fruit oil, palmetto fruit oil, carotene, grape seed oil, and blueberry seed oil.

[0030] Of course, if the oil-soluble active ingredient itself is not easily degraded or oxidized, there is no need to use the system of the present invention; if the system only contains water-soluble active ingredients, since a sunscreen layer has been constructed by the continuous phase containing the oil-soluble sunscreen agent, there is no need to use the system of the present invention. The system of the present invention is particularly aimed at formulations containing oil-soluble active ingredients that are easily degraded or oxidized; however, the system of the present invention does not exclude the encapsulation of only oil-soluble active ingredients that are not easily degraded or oxidized.

[0031] The purpose of using oil-soluble active ingredients in this case is often based on functional needs, such as auxiliary sun protection, improving skin color, etc.; in this case, there are no additional restrictions on the selection of oil-soluble active ingredients.

[0032] In the above-mentioned anti-light damage sunscreen gel, the amount of the oil-soluble sunscreen agent does not exceed 5wt%; the amount of the water-soluble sunscreen agent is 8-13wt%. Generally speaking, in practical applications, the amount of the water-soluble sunscreen agent does not need to be restricted too much, and its effect on stability is not obvious, but it is not recommended to use it in excess of the normal amount.

[0033] In the above-mentioned anti-photodamage sunscreen gel, the oil-soluble sunscreen agent is one or more combinations of octocrylene, homosalate, isoamyl p-methoxycinnamate, polysilicone-15, ethylhexyl methoxycinnamate, and ethylhexyl salicylate;

[0034] The water-soluble sunscreen agent is one or more combinations of disodium phenyl dibenzimidazole tetrasulfonate, terephthalylidene dicamphor sulfonic acid, and phenylbenzimidazole sulfonic acid.

[0035] In the above-mentioned anti-photodamage sunscreen gel, the oil-soluble sunscreen agent is composed of at least three of isoamyl p-methoxycinnamate, polysilicone-15, ethylhexyl methoxycinnamate, and ethylhexyl salicylate.

[0036] In the above-mentioned anti-light damage sunscreen gel, the water-soluble sunscreen agent includes disodium phenyl dibenzimidazole tetrasulfonate and camphor terephthalene sulfonic acid; the amount of disodium phenyl dibenzimidazole tetrasulfonate is 1.5wt% to 5wt%; the amount of camphor terephthalene sulfonic acid is 1.0wt% to 5wt%; preferably, the amount of disodium phenyl dibenzimidazole tetrasulfonate is 1.9wt% to 5wt%; the amount of camphor terephthalene sulfonic acid is 1.3wt% to 5wt%.

[0037] In the above-mentioned anti-photodamage sunscreen gel, the water-soluble sunscreen agent further comprises phenylbenzimidazole sulfonic acid, and the amount of the phenylbenzimidazole sulfonic acid is 5wt% to 9wt%.

[0038] The above-mentioned anti-photodamage sunscreen gel also includes one or more combinations of moisturizers, emollients, pH regulators, and skin protectants.

[0039] In the above-mentioned anti-photodamage sunscreen gel, the amount of the oil-soluble active ingredient is 0.01-1 wt %.

[0040] Beneficial Effects

[0041] The sunscreen gel of the present invention constructs an oil-in-water-in-oil system, wraps the oil-soluble active ingredients in the innermost layer, the second outermost layer is a water layer containing a water-soluble sunscreen agent, and the outermost layer is a continuous phase containing an oil-soluble sunscreen agent. Through the design of two sunscreen layers, the active ingredients in the innermost layer can be prevented from being easily degraded.

[0042] By properly selecting and using emulsifiers, oil-soluble sunscreens, and polydimethylsiloxane, the system can be kept in a transparent gel state. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] Figure 1 Schematic diagram of the preparation of the pre-emulsion of the present invention;

[0044] Figure 2 It is a graph showing the test results of the retained samples of two gels of the present invention. DETAILED DESCRIPTION

[0045] The present invention will be further described below in conjunction with the embodiments, but it does not constitute any limitation to the present invention. Any limited number of modifications made within the scope of the claims of the present invention are still within the scope of the claims of the present invention.

[0046] In order to explain the technical content of the present invention in detail, further description is given below in conjunction with the implementation modes.

[0047] Reagent Source

[0048] Dimethicone: XIAMETER TM PMX-200Silicone Fluid 10cSt N, Dow (Zhangjiagang) Investment Co., Ltd.;

[0049] Phenylbenzimidazole sulfonic acid: Neo Hydro, Dezhixin Flavors & Fragrances (Nantong) Co., Ltd.;

[0050] Disodium phenyl dibenzimidazole tetrasulfonate: Neo AP, Dezhixin Flavors & Fragrances (Nantong) Co., Ltd.;

[0051] Terephthalidene dicamphor sulfonic acid: TC-UV TDSA, Guangzhou Tianci High-tech Materials Co., Ltd.;

[0052] Isoamyl p-methoxycinnamate: Neo E1000, Dezhixin Flavors & Fragrances (Nantong) Co., Ltd.;

[0053] Polysilicone-15: SLX, DSM Vitamins (Shanghai) Co., Ltd.;

[0054] Ethylhexyl Methoxycinnamate: MCX, DSM Nutritional Products Ltd.;

[0055] Ethylhexyl Salicylate: EHS, DSM Vitamins (Shanghai) Co., Ltd.;

[0056] Dimethicone PEG-10 / 15 crosspolymer: SSG-210SP, ShinEtsu;

[0057] PEG-10 polydimethylsiloxane: KF-6017, Shin-Etsu Silicone International Trading (Shanghai) Co., Ltd.;

[0058] Polyquaternium-61: Lipidure-NR; NOF Corporation;

[0059] Polyquaternium-10: UCARE TM Polymer JR-400P; Dow (Zhangjiagang) Investment Co., Ltd.;

[0060] Polyquaternium-6: Bonquat P6; Bonderalia Italia Srl

[0061] PPG-13-decyltetradecyl alcohol polyether-24: SOLUBULE GS-01; NOF Corporation;

[0062] PEG-40 Hydrogenated Castor Oil: CO 40; BASF (China) Co., Ltd.

[0063] Polysorbate 20: Tween 20; Guangdong Runhua Chemical Co., Ltd.

[0064] Astaxanthin: BIO-ASTAO5; Xianting (Guangzhou) Trading Co., Ltd.;

[0065] Guaiazulene: Guaiazulene (version number 01) Jiangsu Jiafu Pharmaceutical Co., Ltd.

[0066] Part I Preparation of Sunscreen Gel

[0067] The preparation method is:

[0068] 1. Add dimethicone, isoamyl p-methoxycinnamate, polysilicone-15, ethylhexyl methoxycinnamate, ethylhexyl salicylate, dimethicone PEG-10 / 15 crosspolymer, and PEG-10 dimethicone into the production tank, stir well, and set aside.

[0069] 2. Add water and terephthalylidene dicamphor sulfonic acid to the water phase pot and heat to 82-85°C, stir evenly, cool to below 45°C, add sodium hydroxide, phenylbenzimidazole sulfonic acid, disodium phenyl dibenzimidazole tetrasulfonate, glycerol, butylene glycol, and glycerol polyether-26 in sequence, stir evenly,

[0070] 3. Slowly add the second step into the first step and stir evenly;

[0071] 4. Add the pre-emulsion to the production tank, stir evenly, take samples for testing, and after passing the test, fill and package them into finished products. The preparation method of the pre-emulsion is: mix polyquaternium salt-61, PPG-13-decyltetradecanol polyether-24, and oil-soluble active ingredients evenly, then slowly add them dropwise into water, accompanied by magnetic stirring, to form an oil-in-water pre-emulsion. The preparation of the pre-emulsion can refer to Figure 1 The schematic diagram shown;

[0072] The formula can be referred to Table 1 to Table 4;

[0073] Table 1 Formula Unit: g

[0074]

[0075] Table 2 Formula Unit: g

[0076]

[0077]

[0078] Table 3 Formula Unit: g

[0079]

[0080] Sample 14

[0081] Referring to the above preparation method, the formula is substantially the same as sample 5, except that polyquaternium-61 is replaced with an equal amount of polyquaternium-6;

[0082] Sample state: semi-transparent essence state.

[0083] Sample 15

[0084] Referring to the above preparation method, the formula is substantially the same as sample 5, except that polyquaternium-61 is replaced with an equal amount of polyquaternium-10.

[0085] Sample state: semi-transparent essence state.

[0086] Sample 16

[0087] With reference to the above preparation method, the formula is substantially the same as that of sample 5, except that PPG-13-decyltetradecyl alcohol polyether-24 is replaced with an equal amount of polysorbate-20.

[0088] Sample state: transparent gel state.

[0089] Sample 17

[0090] With reference to the above preparation method, the formula is substantially the same as that of Sample 5, except that PPG-13-decyltetradecyl alcohol polyether-24 is replaced with an equal amount of PEG-40 hydrogenated castor oil.

[0091] Sample state: transparent gel state.

[0092] Sample 18

[0093] With reference to the above preparation method, the formula is basically the same as sample 5, except that an equal amount of astaxanthin is replaced with guaiac, and its state is a transparent gel state.

[0094] Result analysis:

[0095] 1. It can be seen from Sample 1 and Samples 2-9 that when the oil-in-water-in-oil system is not constructed, the system remains in a transparent gel state;

[0096] 2. It can be seen from Samples 1-10, Samples 11 and Sample 12 that the use of ethylhexyl salicylate, an oil-soluble sunscreen agent, is very critical in the system of the present invention, as it determines the transparency and state of the system.

[0097] 3. It can be seen from samples 2-10, 14 and 15 that the use of polyquaternium-61 emulsifier is also very critical, which also determines the transparency and state of the system.

[0098] 4. It can be seen from samples 2-10 and sample 13 that the emollient polydimethylsiloxane can affect the transparency and state of the system to a certain extent.

[0099] It is clear from the above samples that constructing an oil-in-water-in-oil system will affect the stability of the original system. By controlling the type and amount of oil-soluble sunscreen, the type of solubilizer, and the amount of polydimethylsiloxane, the system can be made into a transparent gel state.

[0100] Part 2 Stability Test

[0101] Test samples:

[0102] Astaxanthin sunscreen gel: Sample No. 5;

[0103] Astaxanthin ordinary gel: the formula of sample No. 5 is adopted, but polyquaternium-61 and PPG-13-decyltetradecyl alcohol polyether-24 are not added to the formula, and only 0.05g astaxanthin is added.

[0104] The samples were used for retention, light exposure and high temperature tests; each group of samples was packed in 3 transparent bottles, one of which was kept away from light, one was placed in a high temperature oven for 24 hours, and the other was placed in a light box with uninterrupted light for 24 hours;

[0105] The test period is from 0 to 28 days;

[0106] Test result reference Figure 2 ;

[0107] It can be seen from the above results that the product of the present invention has good stability under long-term storage, and will not change at room temperature, and only has very slight changes under extreme conditions; while ordinary gel products that do not apply the invention will undergo obvious fading reaction under short-term room temperature conditions. At the same time, it is particularly important to note that ordinary astaxanthin gel will fade even in a light-proof state, but it will fade slower than under light or high temperature.

Claims

1. A sunscreen gel that resists light damage, characterized in that: include: PEG-10 / 15 cross-linked polydimethylsiloxane 2.5-3.5 wt%; PEG-10 polydimethylsiloxane 0.2-0.4wt%; Polydimethylsiloxane 5-10wt%; Water-soluble sunscreen, oil-soluble sunscreen, polyquaternium-61, solubilizer, oil-soluble active ingredient; The dosage of the polyquaternium salt-61 is 0.002-0.02wt%; The solubilizing agent is used in an amount of 0.01 to 0.1 wt %; The oil-soluble sunscreen contains ethylhexyl salicylate; The amount of ethylhexyl salicylate is not less than 2wt%; The remaining amount of water.

2. The anti-light damage sunscreen gel according to claim 1, characterized in that: The solubilizer is one or more combinations of PPG-13-decyltetradecyl alcohol polyether-24, polysorbate-20, and PEG-40 hydrogenated castor oil.

3. The anti-light damage sunscreen gel according to claim 1, characterized in that: The oil-soluble active ingredient is one or more combinations of astaxanthin, guaiac, lithospermum oil, sea buckthorn fruit oil, palm fruit oil, carotene, grape seed oil, and blueberry seed oil.

4. The anti-light damage sunscreen gel according to claim 1, characterized in that: The amount of the oil-soluble sunscreen agent used is no more than 5 wt %; the amount of the water-soluble sunscreen agent used is 8-13 wt %.

5. The anti-light damage sunscreen gel according to claim 1, characterized in that: The oil-soluble sunscreen is one or more combinations of octocrylene, homosalate, isoamyl p-methoxycinnamate, polysilicone-15, ethylhexyl methoxycinnamate, and ethylhexyl salicylate; The water-soluble sunscreen agent is one or more combinations of disodium phenyl dibenzimidazole tetrasulfonate, terephthalylidene dicamphor sulfonic acid, and phenylbenzimidazole sulfonic acid.

6. The anti-light damage sunscreen gel according to claim 5, characterized in that: The oil-soluble sunscreen agent is composed of at least three of isopentyl p-methoxycinnamate, polysilicone-15, ethylhexyl methoxycinnamate and ethylhexyl salicylate.

7. The anti-light damage sunscreen gel according to claim 1, characterized in that: The water-soluble sunscreen comprises disodium phenyl dibenzimidazole tetrasulfonate and camphor terephthalene sulfonic acid; the amount of disodium phenyl dibenzimidazole tetrasulfonate is 1.5 wt % to 5 wt %; the amount of camphor terephthalene sulfonic acid is 1.0 wt % to 5 wt %.

8. The anti-light damage sunscreen gel according to claim 1, characterized in that: The water-soluble sunscreen further comprises phenylbenzimidazole sulfonic acid, and the amount of the phenylbenzimidazole sulfonic acid is 5wt% to 9wt%.

9. The anti-light damage sunscreen gel according to claim 1, characterized in that: It also includes one or more combinations of moisturizers, emollients, pH adjusters, and skin protectants.

10. The anti-light damage sunscreen gel according to any one of claims 1 to 9, characterized in that: The amount of the oil-soluble active ingredient is 0.01-1 wt %.

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