Liquid dispenser with controlled dispensing

Abstract

The disclosed dispenser provides controlled dispensing of liquid. The dispenser has a housing that supports a fluid retention system, a fluid delivery system, a perfusion mechanism, and an actuation control mechanism. The perfusion mechanism generates and stores an actuation force that breaks the sealed fluid delivery system, and the force can be controllably released to dispense the liquid with an actuation control mechanism. The actuation control mechanism includes a plunger slidably advanced by a force from the irrigation mechanism into a barrel containing the fluid. The actuation control mechanism also includes an actuation button that interlocks with the plunger to start and stop dispensing. Optionally, the dispenser has two cartridges and a mixing chamber for dispensing a multi-component liquid, such as an adhesive.

Description

Technical Field

[0001] The present disclosure relates to a liquid dispenser with controlled dispensing of liquid. In particular, the liquid dispenser includes a priming mechanism for generating and storing an actuation force that can be controllably released using an actuation control mechanism to dispense the liquid. Background Art

[0002] Staples and sutures are commonly used for wound closure in an operating room setting. While they are used for high tension and large closures, tissue adhesives are also used for small wounds alone or in combination with internal deep sutures. Tissue adhesives can relieve pain, can lead to better cosmetic results, and provide an antimicrobial barrier against further infection. Tissue adhesives can also be applied quickly compared to staples and sutures. Common tissue adhesives are cyanoacrylate-based compositions that have very low viscosities. In addition, the dispenser is typically a sealed tube containing the tissue adhesive, wherein once the opening is unsealed, the tube is simply squeezed to deliver the low viscosity adhesive. Therefore, these commonly used tissue adhesives are not easy to control when delivered to the wound. Summary of the invention

[0003] The disclosed dispenser provides controlled distribution of liquid. The dispenser has a housing that supports a fluid retention system, a fluid delivery system, a priming mechanism, and an actuation control mechanism. The priming mechanism generates and stores an actuation force that destroys the sealed fluid delivery system, and the force can be controllably released by the actuation control mechanism to distribute the liquid. The actuation control mechanism includes a plunger that is slidably advanced into a barrel containing the fluid by force from the priming mechanism. The actuation control mechanism also includes an actuation button that interlocks with the plunger to start and stop distribution. Optionally, the dispenser has two barrels and a mixing chamber for distributing multi-component liquids.

[0004] The priming mechanism is primed by moving from a first, unprimed position to a second, primed position, compressing the spring and also translating the fluid retaining system into engagement with the fluid delivery system. In particular, a sealed container retaining the fluid is pierced and the contained fluid is then communicated with the fluid delivery system. The energy stored in the spring from the priming is then controllably released via an actuation control mechanism.

[0005] In one embodiment, the liquid dispenser has a proximal end and a distal end, and a housing that supports a fluid retention system, a fluid delivery system, an injection mechanism, and an actuation control mechanism, the actuation control mechanism having an applicator tip at the distal end. The fluid retention system includes a first barrel with a seal for retaining a first liquid, a first piston that can slide in the first barrel. The fluid delivery system includes a first puncture element and a nozzle extending from the first barrel to the applicator tip. The injection mechanism includes an injection button slidably connected to the housing, a spring disposed in the injection button, and an injection latch extending from the injection button. The actuation control mechanism includes a plunger slidably connected to the housing, the plunger including a first fluid dispensing arm engaged with the first piston, and a plurality of plunger engagement extensions. Each plunger engagement extension is spaced apart from an adjacent plunger engagement extension. The spring abutment surface contacts the spring. The actuation button is connected to a plurality of actuation engagement extensions. Each actuation extension is spaced apart from an adjacent actuation extension by an actuation extension gap. The priming button is movable from a first, unprimed position to a second, primed position, wherein in the second priming position (i) the priming latch is locked with a priming movable retainer in the housing to restrict movement in the proximal direction and the spring is compressed against the spring abutment surface of the plunger, and (ii) the puncture element is engaged into the first barrel by a seal.

[0006] In one embodiment, the actuation button is movable from a first engaged position, in which the actuation engagement extension is interconnected with the plunger engagement extension to limit movement of the plunger, to a second disengaged position, in which the actuation engagement extension is disengaged from the plunger engagement extension.

[0007] In one embodiment, the fluid retention system further comprises a second barrel retaining a second liquid and a second piston slidable within the second barrel, and wherein the plunger further comprises a second fluid dispensing arm engaged with the second piston.

[0008] The actuation button is in a first engaged position in the rest position, and displacement of the actuation button into the housing moves it to a second disengaged position. When the priming button is in the first unprimed position, the priming latch locks with a priming rest retainer in the housing to restrict movement in the proximal direction.

[0009] In one embodiment, a method of dispensing a liquid from a dispenser includes moving a priming mechanism to a second priming position, wherein the priming latch is retained in a priming movable retainer and compresses a spring against a spring abutment surface, and actuating the actuation button to disengage the actuation engagement extension from the plunger engagement extension, so that the spring slidably moves the spring abutment surface and the first fluid displacement arm of the plunger in a first fluid barrel. In addition, the method includes actuating the actuation button to engage the actuation engagement extension, the plunger engagement extension, thereby stopping the slidable movement of the plunger. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] Figure 1 is a cross-sectional view of one embodiment of a liquid dispenser with controlled dispensing;

[0011] Figure 2 yes Figure 1 An exploded perspective view of a disassembled dispenser;

[0012] Figure 3 is in the storage, unfilled position Figure 1 A cross-sectional view of an assembled dispenser;

[0013] Figure 4 yes Figure 1 A cross-sectional view of the assembled dispenser in a priming position with the actuation control mechanism not released and not dispensing liquid;

[0014] Figure 5 yes Figure 1 a cross-sectional view of the assembled dispenser in a priming position with the actuation control mechanism partially released and dispensing liquid;

[0015] Figure 6 yes Figure 1 A cross-sectional view of the assembled dispenser in a priming position with the actuation control mechanism fully released and liquid having been fully dispensed;

[0016] Figure 7 yes Figure 3 A perspective cutaway view of an actuation control mechanism of a liquid dispenser;

[0017] Figure 8 yes Figure 4 A cross-sectional view of the assembled dispenser showing the path of liquid flowing out of the dispenser;

[0018] Fig. 9A is a perspective view of one embodiment of an applicator tip for a liquid dispenser;

[0019] Fig. 9B is a front perspective view of an embodiment of an applicator tip for a liquid dispenser;

[0020] Fig. 9C is a perspective view of an embodiment of an applicator tip for a liquid dispenser;

[0021] Fig.9D is a side cross-sectional view of an applicator tip for a liquid dispenser;

[0022] FIG. 10A to FIG. 10F is a perspective view of an embodiment of a puncture element;

[0023] Fig.11is a perspective view of a second embodiment of a liquid dispenser.

[0024] Although the above-mentioned drawings illustrate embodiments of the present invention, as pointed out in the discussion, other embodiments are also contemplated. In all cases, the present disclosure presents the present invention in an exemplary and non-restrictive manner. Those skilled in the art may design many other modifications and embodiments that fall within the scope and spirit of the present invention. The accompanying drawings may not be drawn to scale. DETAILED DESCRIPTION

[0025] Various designs for liquid dispensers are disclosed. The disclosed liquid dispenser 100 includes a priming mechanism 400 that generates and stores an actuation force that can be controllably released using an actuation control mechanism 500 to dispense contained liquid 311 .

[0026] Figure 1 is a perspective view of a liquid dispenser 100 for controlled dispensing. Figure 2 yes Figure 1 1 is an exploded perspective view of the disassembled dispenser 100. Figures 3 to 6 The actuation process of the dispenser 100 is shown. Figure 7 An actuation control mechanism 500 of the dispenser 100 is shown. Figure 8 A first liquid 311 and a second liquid 321 dispensed from the dispenser 100 are shown. Fig. 9A 9E shows an alternative embodiment of the applicator tip 220. FIG. 10A to FIG. 10F Alternative embodiments of piercing elements 352, 354 are shown. Common reference numerals in the drawings will be used for common elements.

[0027] Dispenser 100 includes housing 200. Housing 200 supports, holds or accommodates some or all of the components. Dispenser 100 includes fluid retention system 300, fluid delivery system 350, priming mechanism 400 and actuation control mechanism 500, each of which will be described in more detail below. Housing 200 is fixed, while some or all of fluid retention system 300, priming mechanism 400 and actuation control mechanism 500 move relative to housing 200.

[0028] The elements of the dispenser 100 will be described. Figure 2 , Figure 7 , Fig. 9A To Figure 9E and FIG. 10A to FIG. 10F The relative motion of the dispenser 100 will be Figures 3 to 6 Described in. case

[0029] like Figure 1As shown, the housing 200 has a distal end 202 and a proximal end 204 opposite the distal end 202. Generally, the housing 200 extends along a longitudinal axis 205. An applicator tip 220 is located at the distal end 202, from which the contained liquid 311 is dispensed. Generally, for ease of assembly, the housing 200 has a top housing 210 and a bottom housing 212 that are connected together to contain the internal components. Various support features can be formed in the housing 100 to provide structural stability to the housing 100 itself and to provide a resting surface for the components contained in the housing 200.

[0030] Within the walls of the top housing 210 or the bottom housing 212 or both are a perfusion stationary retainer 230 and a perfusion movable retainer 232 (see Figures 3 to 6 ). When the filling button 410 is in the first non-filling position ( Figure 3 ), the priming stationary retainer 230 receives the priming latch 430 of the priming button 410. When the priming button is actuated to the second priming position ( Figure 4 ), the priming movable retainer 232 receives the priming latch 430. In one embodiment, the dispenser 100 is a single-use item, and thus for both the priming stationary retainer 230 and the priming movable retainer 232, the interface with the priming latch 430 enables the priming mechanism 400 to slide from the proximal end 204 to the distal end 202 without being released back into the proximal end 204. In other embodiments, the dispenser 100 may be reusable, and thus, the priming latch 430 may be released via actuation from the priming stationary retainer 230 or the priming movable retainer 232, so that the priming mechanism 400 may be released and reactivated.

[0031] Within the housing 200, extending from the top housing 210 or the bottom housing 212, or both, is a cartridge holder 240. The cartridge holder 240 is a deformable protrusion that holds the fluid retention system 300 in a position prior to activation by the priming mechanism 400. This can provide stability during storage and prevent damage or leakage. When the priming mechanism 400 is activated, sufficient force is applied to deform, rupture or collapse the cartridge holder 240 and allow the fluid retention system 300 to translate within the housing 200 in a direction toward the distal end 202, as shown in FIG. Figure 4 This translation allows the barrel to be pierced by a piercing mechanism of a fluid delivery system.

[0032] The housing 200 may include a delivery indicator opening 250, such as Figure 2 or Fig.11As will be described in more detail below, the actuation control mechanism 500 is slidably moved during dispensing, and a portion of the actuation control mechanism 500 may be visible through the delivery indicator opening 250. This may provide a visual indication to the user when how much redispensing distance is remaining, giving an indication of how much liquid is left to be dispensed. Fluid retention system

[0033] like Figure 1 and Figure 2 As best shown, the fluid retention system 300 has a first fluid cylinder 310, a first piston 312 at the proximal end 204, and a first seal 314. The first fluid cylinder 310 retains a first liquid 311. Figure 8 ) The first piston 312 is assembled in the first fluid cylinder 310 and can slide in the first cylinder 310. The first liquid 311 can be any number of viscous components. For example, the first liquid 311 can be an adhesive, a skin protectant, an oil, or a solvent.

[0034] like Figure 2 and Figure 3 As shown, the fluid holding system 200 optionally further comprises a second fluid cylinder 320 for holding a second liquid 321. The second fluid cylinder 320 further comprises a second piston 322 mounted in the second fluid cylinder 320.

[0035] Typically, during storage and before use, the first liquid 311 is sealed in the first fluid cylinder 310 by a first seal 314, and the second liquid 321 is sealed in the second fluid cylinder 320 by a second seal 324. The seals 314, 324 are typically pierceable membranes and can be multi-layer laminates that are welded or otherwise secured to the cylinders for a secure seal. In alternative embodiments, a septum contained within the first fluid cylinder 310 (and the second fluid cylinder 320, if included) can be used instead of a seal pierced by a piercing element.

[0036] The optional barrel extension 330 can extend from the first fluid barrel 310 toward the proximal end 204. In use, as described below, when the priming mechanism 400 is primed ( Figure 4 ), a portion of the priming cap 414 presses against the cartridge extension 330 to displace the cartridge holder 240 and actuate the first fluid cartridge 310. In this embodiment, after priming, the first piercing element 352 pierces the first seal 314 (as well as the second piercing element 354 and the second seal 324, if included).

[0037] Optional plunger engagement tab 340 ( Figure 2) extends from the fluid retention system. The plunger engagement tab 340 is slidably received in the tab channel 521 of the actuation control mechanism 500 to securely and slidably connect the fluid retention system 300 with the actuation control mechanism 500 and in particular with the plunger 520.

[0038] In some embodiments, it is advantageous to include both the first liquid 311 and the second liquid 321. For example, the first liquid 311 and the second liquid 321 can be materials that are incompatible and separated from each other during storage but have the advantage of being used together. For example, the first liquid 311 and the second liquid 321 can react with each other, so they must be separated during storage, and change when mixed in use. In one embodiment, the first liquid 311 and the second liquid 321 are two-part adhesive systems that are cross-linked together. An example of a two-part adhesive includes an epoxy system, and a specific example is hydrophobic oxalate and polyethyleneimine. Each liquid 311 is viscous, and when in contact with another liquid, the liquid will mix, cross-link or solidify and begin to harden.

[0039] Typically, adhesives used on the skin are one-part cyanoacrylate adhesives that have very low viscosity, are exothermic when cured, and are brittle when cured. Dispensers that can control the delivery of two-part systems expand the options for biocompatible, strong, and fast-curing adhesives for skin applications. Fluid delivery systems

[0040] like Figure 2 , Figure 3 , Figure 4 As best shown, extending from the fluid holding system 300 is a fluid delivery system 350. The fluid delivery system 350 has a first piercing element 352 and a nozzle 360 ​​at the distal end 202. The first fluid barrel 310 holds a first liquid 311. The nozzle 360 ​​extends from the first fluid barrel 310 to dispense the first liquid 311.

[0041] The nozzle 360 ​​can dispense the liquid 311 without a separate applicator tip 220. As shown in this embodiment, the nozzle 360 ​​is within the applicator tip 220, so that the applicator tip 220 can be shaped to spread the first liquid 311 only outside the nozzle 360 ​​in the length or width direction. In addition, the applicator tip 220 can have a wide edge to allow the dispensed first liquid 311 to be scraped, spread, or wiped.

[0042] Various embodiments of the applicator tip 220 are described in 9A to 9D . The applicator tip 220 allows the user to shape the liquid 311 during dispensing. The applicator tip 220 may include a dimple 222 adjacent to the location of the nozzle 360. This Fig.9DActuation of the applicator tip 220 allows the recess 222 to be filled with the liquid 311 and released to control the flow rate to the target surface independently of the rate of dispensing from the nozzle 360. Fig. 9B The curved surface of the applicator tip 220, best shown in FIG. 1 , controls the width and height of the dispensed liquid 311 by the tilt of the angle at which the dispenser 100 is held against the target surface.

[0043] The applicator tip 220 can be soft or rigid, depending on the viscosity of the dispensed liquid 311. In addition, the applicator tip 220 can be used to reshape the liquid 311 that has not completely solidified.

[0044] In an embodiment having a second fluid barrel 320, a separate nozzle may extend from the second fluid barrel 320 to dispense the second liquid 321. As shown in this embodiment, the nozzle 340 is secured to the first fluid barrel 310 and the second fluid barrel 320. In this embodiment, adjacent to the first fluid barrel 310 and the second barrel 320 is a mixing chamber 356 into which the first liquid 311 enters and into which the second liquid 321 enters before passing through the nozzle 360. A first barrel liner 316 and a second barrel liner 326 may be included in the interface between the nozzle 360 ​​(or mixing chamber 356, if included) and the first fluid barrel 310, the second fluid barrel 320, respectively. Typically, these barrel liners 316, 326 are flexible, compliant and rubbery materials. As shown in FIG. Figure 3 As best shown, the barrel liners 316, 326 include recessed portions and as shown in FIG. Figure 4 As shown, a portion of the cylinder gaskets 316, 326 enters the first fluid cylinder 310 and the second fluid cylinder 320, respectively, to form a tight seal and prevent the liquids 311, 321 from leaking. A portion of the cylinder gaskets 316, 326 remains outside the first fluid cylinder 310 and the second fluid cylinder 320 ( Figure 4 Optionally, within the nozzle 430 is a static mixer 364 for enabling mixing of the first liquid 311 and the second liquid 321 prior to dispensing from the nozzle 360 ​​.

[0045] Typically, during storage and before use, the first liquid 311 is sealed in the first fluid barrel 310 by the first seal 314, and the second liquid 321 is sealed in the second fluid barrel 320 by the second seal 324. The actuation of the fluid retention system 300 caused by the activation of the priming mechanism 500 causes the first fluid barrel 310 to engage with the first puncture element 352 to pierce the first seal 314. Similarly, if included, the actuation of the priming mechanism 500 and the fluid retention system 300 can cause the second fluid barrel 320 to engage with the second puncture element 354 to pierce the second seal 324. The seals 314, 324 are typically pierceable membranes and can be multi-layer laminates that are welded or otherwise fixed to the barrel for a secure seal. In alternative embodiments, a septum contained in the first fluid barrel 310 (and the second fluid barrel 320, if included) can be used instead of a seal pierced by a puncture element.

[0046] The piercing elements 352, 354 are shaped with tips 353, 355 to pierce, puncture, cut the seals 314, 324. The rest of the piercing elements 352, 354 is wider and larger than the tips 353, 355 to press the pierced, pierced, cut seals 314, 324 away from the fluid path within the piercing elements. Therefore, the pierced seals 314, 324 are less likely to block the dispensed liquids 311, 321. FIG. 10A to FIG. 10F Alternative embodiments of puncturing elements 352 , 354 having pointed ends 353 , 355 are shown. Perfusion mechanism

[0047] The priming mechanism 400 has a priming button 410, a spring 420, and at least one (here several) priming latches 430. Optionally, there is a spring seat 412 in the priming button 410 for securely holding the spring 420. Optionally, directly at the proximal end 204 is a priming cap 414 that can be separated from the priming button 410 and holds the spring seat 412.

[0048] The priming mechanism 400 moves relative to the housing 200 to compress or further compress the spring 420. In this embodiment, the priming mechanism 400 is located at the proximal end 204 of the housing 200. In the first unprimed position, the spring 420 may be in a static position or slightly compressed. In the second priming position, where the priming mechanism 400 has moved toward the distal end 202, the spring 420 becomes more compressed. In addition, the priming latch 430 is fixed in the priming movable retainer 232 to hold the priming mechanism 400 and the compressed spring 420 in place. Actuation control mechanism

[0049] The actuation control mechanism 500 includes an actuation button 510 and a slidable plunger 520. The actuation control mechanism 500 controls the start and stop of dispensing of the contained liquid 311, 321. Figure 7 A perspective cutaway view of a portion of the actuation button 510 and the slidable plunger is shown in a locked engagement position.

[0050] The actuation button 510 is accessible from the exterior portion of the housing 200. The actuation button 510 can be pressed inwardly into the housing 200. In this embodiment, the actuation button 510 is connected to the housing at a hinge 514, and is separated from the housing at a frame 515 in the remaining portion of the actuation button 510 except the hinge 514. This arrangement allows the actuation button 510 to flex at the hinge 514, and due to the disconnection at the frame 515, the actuation button 510 can be pressed inwardly into the housing 200. Other embodiments of the actuation button 510 may be included as long as it is bent inwardly relative to the housing 200.

[0051] The actuation engagement extensions 512 are connected to the actuation button 510, and each actuation engagement extension is separated from the adjacent actuation engagement extension by an actuation extension gap 513. As can be seen in this embodiment, these actuation engagement extensions 512 are similar to a series of teeth or gears. Since the actuation engagement extensions 512 are connected to the actuation button 510, the movement of the actuation button 510 causes similar movement of the actuation engagement extensions 512.

[0052] The plunger 520 provides a contact connection with the priming mechanism 400 and selective engagement and disengagement with the actuation control button 510 to start or stop dispensing the liquid 311, 321 from the fluid holding system 300. The plunger 520 includes a displacement arm for each fluid cylinder. In this embodiment, the plunger 520 has a first fluid displacement arm 522 to engage with the first fluid cylinder 310, thereby pressing the first liquid 311 from the first fluid cylinder 310. The plunger 520 has a second fluid displacement arm 524 to engage with the second fluid cylinder 320, thereby pressing the second liquid 321 from the second fluid cylinder 320.

[0053] The spring abutment surface 530 of the plunger 520 is adjacent to the spring 420. In the first unprimed position or the second primed position, the pressing force from the spring 420 presses on the spring abutment surface 530.

[0054] The plunger 520 includes a plunger engagement extension 526, each of which is separated from an adjacent plunger engagement extension by a plunger extension gap 528. As can be seen in this embodiment, these plunger engagement extensions 526 are similar to a series of teeth or gears. When locked, (i) the plunger engagement extension 526 cooperates with the actuation extension gap 513, and (ii) the actuation engagement extension 512 cooperates in the plunger extension gap 528. In order to disengage, the actuation button 510 is pressed, which causes the connected actuation engagement extension 512 and the actuation extension gap 513 to also move and disconnect from the engagement with the plunger engagement extension 526 and the plunger extension gap 528. When the spring 420 is pressed on the spring abutment surface 530 and the actuation control mechanism is disengaged, the plunger 520 moves longitudinally toward the distal end 202, thereby engaging with the fluid retention system 300. The plunger 520 strikes the piston 312, 322 using the momentum from the gap between the plunger 520 and the piston 312, 322. This momentum is used to release the piston 312, 322 from the inner wall 310, 320 of the cylinder. The piston 312, 322 is then driven through the cylinder. Figure 2 As best seen in the figure, the ends of the pistons 312, 322 at the distal end 202 expand slightly to expand against the inner walls of the barrels 310, 320 as the pistons traverse during dispensing (typically the barrels are stretched to be narrower at the piston end and wider at the sealing end) so that there is no increased friction during dispensing. use

[0055] Figures 3 to 6 There are shown various steps for using the dispenser 100. Not all reference numerals are used to illustrate actuation in these figures.

[0056] Figure 3 Is in storage, unfilled position Figure 120. A cross-sectional view of the assembled dispenser 100 is shown in FIG. 20. In the storage, unprimed position, the liquids 311, 321 are enclosed and sealed within the respective barrels 310, 320 to prevent leakage. In this unprimed position, the priming mechanism 400 is in a maximum extended position toward the proximal end 204. The priming latch 430 is in the priming stationary retainer 230, which prevents the priming mechanism 400 from being completely removed from the housing 200. The spring 420 can be relaxed, but more typically the spring 420 is slightly compressed against the spring abutment surface 530 to prevent slipping and rattling. The engagement of the actuation engagement extension 512 of the actuation control mechanism 500 with the plunger engagement extension 526 of the plunger 520 holds the plunger 520 from moving. Additionally, the cartridge retainer 240 is adjacent the fluid retaining system 300 on the side opposite to the pressure applied from the spring 420 to the spring abutment surface 530 and provides a slight resistance to positioning the seals 314, 324, preventing premature contact with the puncture elements 352, 354 prior to priming.

[0057] Figure 4 yes Figure 1 5. A cross-sectional view of the assembled dispenser 100 in the primed position and with the actuation control mechanism 500 in a locked engagement position with the plunger 520. In the primed position, the priming mechanism 400 is actuated longitudinally within the housing 200 toward the distal end 202. The priming latch 430 is in the priming movable retainer 232, which retains the priming mechanism 400 in the primed position and prevents the priming mechanism 400 from returning to the unprimed position. For a single-use dispenser, this is essentially irreversible, and once the device is primed, it remains primed. In some embodiments, the dispenser may be reusable, and therefore the priming latch 430 will disengage from the priming movable retainer 232. As shown in FIG. Figure 3 As shown, in the primed position, the spring 420 is more compressed than in the unprimed position. The compressed spring in the primed position generates the force required to dispense the fluid.

[0058] exist Figure 4 In the prime position, when the Prime button is switched from the first unprimed ( Figure 3 ) position moves to the injection position ( Figure 4 ), the priming mechanism 400 translates the first barrel 310 into contact with the first piercing element 352 to form an open fluid path between the fluid retention system 300 and the fluid delivery system 350. A portion (412) of the priming mechanism 400 actuates against the barrel extension 300 to translate the barrel toward the distal end and rupture / bend the barrel retainer 240. This causes the barrels 310, 320 to engage with the piercing elements 352, 354 to pierce the seals 314, 324. Although in Figure 4In this priming position shown, the fluid barrels 310, 320 are engaged with the piercing elements 352, 354 to open the sealed barrels, but the actuation control mechanism 500 is still in the locked engagement position and the plunger 520 has not yet been activated to press against the barrels 310, 320 to force dispensing of the liquids 311, 321.

[0059] Figure 5 yes Figure 1 A cross-sectional view of the assembled dispenser 100 in the priming position and the actuation control mechanism 500 partially releasing and dispensing the liquids 311, 321. The priming mechanism 400 is in the same position as the Figure 4 524. The actuation control button 510 and the connected actuation engagement extension 512 have been pressed and bent inwardly at the hinge 514 toward the housing 200. This causes the actuation engagement extension 512 to disengage from the plunger engagement extension 526. As a result, the plunger 520 becomes free to slide relative to the housing 200. The spring 420 presses on the spring abutment surface 530, thereby translating the movement of the plunger toward the distal end 202. The displacement arms 522, 524 engage with the first fluid barrel 310 to force the first liquid 311 to the nozzle 360, and, if included, engage with the second fluid barrel 320 to force the second liquid 321 to the nozzle 360. The liquids 311, 321 enter the nozzle 360 ​​and are dispensed from the dispenser 100.

[0060] If included, the liquids 311, 321 enter a mixing chamber before entering the nozzle 360. If included, the liquids 311, 321 pass through a static mixer 364 through the nozzle 360 ​​to achieve mixing of the first liquid 311 with the second liquid 321 before being dispensed from the dispenser 100. The spring constant affects the rate at which the liquids 311, 321 are dispensed. Therefore, to accommodate for dispensing that is too fast or too slow, springs of different constants can be used.

[0061] Figure 6 yes Figure 1 A cross-sectional view of the assembled dispenser in the priming position with the actuation control mechanism 500 fully released and the liquids 311, 321 fully dispensed. The priming mechanism 400 is in the same position as the Figure 4 The same position as described in Figure 5 Here, the spring 420 has pressed against the spring abutment surface 530 and thus the plunger 520 has fully entered the fluid barrel 310 , 320 .

[0062] Figure 8 yes Figure 4, showing the paths of the first liquid 311 passing from the first fluid cartridge 310 and the second liquid 321 passing from the second fluid cartridge 320 into the mixing chamber 356 and then into the nozzle 360 ​​including the static mixer 364 . manufacture

[0063] Dispenser is made of materials and methods commonly used by those skilled in the art. For example, dispenser is typically formed by all or combination of polymer materials, adhesives, metals. For example, rigid materials for parts such as housing, perfusion mechanism, plunger and mixing chamber can be formed by polymethyl methacrylate (PMMA), acrylonitrile butadiene styrene (ABS), polycarbonate (PC) or ABS / PC blends. Elastomers (for seals and gaskets) or semi-rigid materials for parts such as pistons can be formed by thermoplastic elastomers, thermoplastic polyurethanes, thermoplastic vulcanizates, silicones, polyethylene (HDPE, LLDPE, MDPE) or polypropylene. Seals can be formed by foil such as aluminum, ideally with a polymer layer compatible with the surface to which it will be combined. Dispenser is manufactured by assembling individually molded, 3-D printed parts that are combined, fixed, and sealed together in a commonly used method. When used as a dispenser for medical items, the dispenser should be able to withstand sterilization.

[0064] Although specific embodiments have been shown and described herein, it should be understood that these embodiments are merely illustrations of many possible specific arrangements that can be designed in the application of the principles of the present invention. Without departing from the spirit and scope of the present invention, those skilled in the art can design many and varied other arrangements based on these principles. The scope of the present disclosure should not be limited to the structures described in this application, but only to the structures described in the language of the claims and the equivalents of those structures.

Claims

1. A liquid dispenser having a proximal end and a distal end, the liquid dispenser comprising: a housing supporting a fluid retention system, a fluid delivery system, an priming mechanism, and an actuation control mechanism having an applicator tip at the distal end; The fluid retention system comprises: A first cylinder having a sealing member, the first cylinder being used to hold a first liquid; a first piston, the first piston being able to slide within the first cylinder; The fluid delivery system comprises: a first piercing element; a nozzle extending from the first barrel to the applicator tip; The perfusion mechanism comprises: a priming button slidably connected to the housing; a spring, the spring being disposed in the filling button; a priming latch extending from the priming button; The actuation control mechanism comprises: A plunger slidably connected to the housing, the plunger comprising: a first fluid dispensing arm engaged with the first piston; a plurality of plunger engagement extensions, wherein each plunger engagement extension is spaced apart from an adjacent plunger engagement extension; a spring abutment surface, the spring abutment surface in contact with the spring; an actuation button coupled to a plurality of actuation engagement extensions, wherein each actuation extension is spaced apart from an adjacent actuation extension by an actuation extension gap; Wherein the priming button is movable from a first, unprimed position to a second, primed position to translate the first barrel into contact with the first piercing element and form an open fluid path between the fluid retaining system and the fluid delivery system.

2. A liquid dispenser according to claim 1, wherein in the second priming position, the priming latch is locked with a priming movable retainer in the housing to restrict movement in the proximal direction and compresses the spring against the spring abutment surface of the plunger.

3. A liquid dispenser according to any one of the preceding claims, wherein in the second filling position, the spring is more compressed than in the first unfilled position, and the spring in the filling position generates a force for dispensing the first liquid.

4. A liquid dispenser according to any one of the preceding claims, wherein the actuating button is capable of moving from a first engaged position to a second disengaged position, wherein in the first engaged position, the actuating engagement extension is interconnected with the plunger engagement extension to limit the movement of the plunger, and in the second disengaged position, the actuating engagement extension is disengaged from the plunger engagement extension.

5. A liquid dispenser according to any one of the preceding claims, Wherein the fluid retention system further comprises: a second cylinder, the second cylinder retaining a second liquid; and a second piston, the second piston being able to slide within the second cylinder; wherein the plunger further comprises a second fluid dispensing arm engaged with the second piston; The fluid delivery system further comprises a second puncture element.

6. The liquid dispenser of claim 5, wherein the nozzle receives the first liquid and the second liquid.

7. A liquid dispenser according to any one of the preceding claims, wherein the nozzle comprises a static mixer.

8. The liquid dispenser of any one of the preceding claims, further comprising a mixing chamber connecting the first and second barrels to the nozzle.

9. The liquid dispenser of any preceding claim, wherein the applicator tip comprises a depression adjacent the nozzle.

10. The liquid dispenser of any one of the preceding claims, further comprising a barrel liner surrounding the first piercing element to form a sealing contact between the housing and the pierced first barrel.

11. The liquid dispenser of any one of the preceding claims, wherein the first piercing element comprises a tip and a body, wherein the body is substantially aligned within the first barrel to displace the seal.

12. The liquid dispenser of any preceding claim, wherein the actuation button is accessible at the housing.

13. A liquid dispenser according to any one of the preceding claims, wherein the actuation button is in the first engaged position in a rest position and displacement of the actuation button into the housing moves it to the second disengaged position.

14. The liquid dispenser of any one of the preceding claims, wherein with the fill button in the first unfilled position, the fill latch locks with a fill stationary retainer in the housing to restrict movement in a proximal direction.

15. A liquid dispenser according to any one of the preceding claims, comprising a plurality of priming latches.

16. The liquid dispenser of any of the preceding claims, wherein the fluid retention system further comprises a plunger engagement tab slidably received within a tab channel in the plunger.

17. A method of dispensing a liquid from the dispenser of claim 1, the method comprising: moving the priming mechanism to the second priming position wherein the priming latch is retained in the priming movable retainer and the spring is compressed against the spring abutment surface; The actuation button is actuated to disengage the actuation engagement extension from the plunger engagement extension, causing the spring to slidably move the spring abutment surface and first fluid displacement arm of the plunger in a first fluid barrel.

18. The method according to claim 17, further comprising: The actuation button is actuated to engage the actuation engagement extension, the plunger engagement extension, and thereby stop the slidable movement of the plunger.

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