Traditional Chinese medicine composition capable of relieving sore throat, medicinal preparation and preparation method of medicinal preparation
Through the clearing and detoxifying effects of traditional Chinese medicine compositions such as Jinbuckwheat, the problem of limited treatment effect of acute pharyngitis is solved, effective treatment of acute pharyngitis is achieved, and superior in safety and cost are shown.
Patent Information
- Application Number
- CN202411671425.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-21
- Publication Date
- 2025-01-10
AI Technical Summary
The prior art has problems with limited therapeutic effects and insufficient drug safety in the treatment of acute pharyngitis, especially in the case of complex and diverse causes and common viral infections. It is difficult for existing drugs to effectively solve the pain of the throat, dry throat, and burning pharyngeal fever. Symptoms.
The traditional Chinese medicine composition of Jin buckwheat, Scutellaria baicalensis, Fritillaria zheba, Loquat leaves, Knotweed, Scrophularia ginseng, Brocade lantern, Dendrobium, Arhat fruit and licorice is used to clear heat and detoxify, and to reduce swelling, form a traditional Chinese medicine composition of pharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal apharyngeal a and pharmaceutical preparations, used to treat acute pharyngitis, and are prepared into tablets, capsules or oral liquids by water extraction.
This traditional Chinese medicine composition has a good therapeutic effect on acute pharyngitis. The patient has no obvious adverse reactions during use. The preparation method is simple, low-cost, and easy to administer. It has significant therapeutic advantages.
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Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of medicines, and in particular relates to a throat-relieving Chinese medicine composition, a pharmaceutical preparation and a preparation method thereof. Background Art
[0002] Acute pharyngitis is a primary diagnosis and treatment disease in the Department of Otolaryngology. It develops rapidly and has a high incidence rate. The main clinical manifestations are sore throat, dry throat, and burning sensation in the throat, occasionally accompanied by dysphagia, fever, headache, lymphadenopathy and other milder symptoms. At present, the causes of acute pharyngitis are complex and diverse, including viral infection, bacterial infection and other physical and chemical factors. Among them, viral infection is more common, accounting for more than half of the total causes, followed by bacterial infection. The onset season of acute pharyngitis is not obvious. It is prone to occur during climate change and seasonal changes. There is no obvious regional difference. It can occur in men, women, old and young, and is widely distributed in the population. At present, clinical treatment is mainly symptomatic analgesic, including oral analgesics, gargle drugs, nebulization, etc., and antiviral drugs and antibiotics are given when necessary.
[0003] Traditional Chinese medicine classifies "acute pharyngitis" as "laryngitis", and the understanding of it has a long history. According to modern archaeological research, the name of laryngitis was first recorded in the ancient Western Han Dynasty medical book "Fifty-two Disease Prescriptions". The classic Chinese medicine book "Inner Canon" discusses the etiology, pathogenesis and clinical manifestations of laryngitis in detail, emphasizing the pathogenesis of laryngitis, believing that it is caused by dysfunction of internal organs, imbalance of yin and yang, and evil heat and toxic gas, which lead to blockage of the throat qi and meridians, thus causing the disease. Many doctors in later generations have conducted extensive discussions on laryngitis based on the "Inner Canon", enriching the understanding of laryngitis in traditional Chinese medicine. With the development of modernization of traditional Chinese medicine, modern pharmacology has found through purification and separation of effective ingredients of traditional Chinese medicine that the effective ingredients not only have the effect of inhibiting the growth and reproduction of pathogens and regulating immunity, but are also safe and reliable, and are not easy to produce drug resistance.
[0004] However, the current drugs for treating acute pharyngitis have their own advantages and disadvantages, and more different types of drugs for treating acute pharyngitis still need to be developed. Summary of the invention
[0005] In view of the shortcomings of the prior art, the present invention aims to provide a Chinese medicine composition for relieving pharyngitis, a pharmaceutical preparation and a preparation method thereof. The Chinese medicine composition and the pharmaceutical preparation have a good therapeutic effect on acute pharyngitis and have no obvious adverse reactions in patients.
[0006] To achieve this object, the present invention adopts the following technical solutions:
[0007] In a first aspect, the present invention provides a Chinese medicine composition for relieving throat pain, the Chinese medicine composition comprising the following components:
[0008] Fagopyrum scabra, Scutellaria baicalensis, Fritillaria thunbergii, loquat leaf, Polygonum cuspidatum, Scrophularia ningpoensis, Lantern Festival, Dendrobium candidum, Momordica grosvenori and Licorice.
[0009] In some embodiments of the present invention, the throat-relieving Chinese medicine composition comprises the following components in parts by weight:
[0010] 4-12 parts of golden buckwheat, 5-13 parts of scutellaria, 2-10 parts of thunbergia thunbergii, 4-12 parts of loquat leaves, 2-10 parts of knotweed, 4-12 parts of figwort, 4-12 parts of lanterns, 2-10 parts of dendrobium, 2-8 parts of momordica grosvenori and 1-5 parts of liquorice.
[0011] The weight proportion of golden fagopyrum can be, for example, 4, 5, 6, 7, 8, 9, 10, 11 or 12 parts, etc. However, the present invention is not limited to the listed values, and other values not listed within the range are also applicable.
[0012] The weight proportion of Scutellaria baicalensis radix can be, for example, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts, 12 parts or 13 parts, etc. However, the present invention is not limited to the listed values, and other values not listed within the range are also applicable.
[0013] The weight parts of Fritillaria thunbergii can be, for example, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0014] The weight proportion of loquat leaves can be, for example, 4, 5, 6, 7, 8, 9, 10, 11 or 12 parts, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0015] The weight proportion of knotweed can be, for example, 2, 3, 4, 5, 6, 7, 8, 9 or 10 parts, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0016] The weight proportion of Scrophularia ningpoensis can be, for example, 4, 5, 6, 7, 8, 9, 10, 11 or 12 parts, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0017] The weight parts of the brocade lantern can be, for example, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts or 12 parts, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0018] The weight proportion of the dendrobium can be, for example, 2, 3, 4, 5, 6, 7, 8, 9 or 10 parts, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0019] The weight proportions of Momordica grosvenori can be, for example, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 6.5, 7, 7.5 or 8, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0020] The weight proportion of liquorice can be, for example, 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts or 5 parts, etc. However, the present invention is not limited to the listed values, and other unlisted values within the range are also applicable.
[0021] In some embodiments of the present invention, the throat-relieving Chinese medicine composition comprises the following components in parts by weight:
[0022] 6-10 parts of golden buckwheat, 7-11 parts of scutellaria, 4-8 parts of thunbergia thunbergii, 6-10 parts of loquat leaves, 4-8 parts of knotweed, 6-10 parts of figwort, 6-10 parts of brocade lantern, 4-8 parts of dendrobium, 3.5-6.5 parts of momordica and 2-4 parts of liquorice.
[0023] In some embodiments of the present invention, the throat-relieving Chinese medicine composition comprises the following components in parts by weight:
[0024] 8 parts of golden buckwheat, 9 parts of scutellaria, 6 parts of thunbergia thunbergii, 8 parts of loquat leaves, 6 parts of polygonum cuspidatum, 8 parts of figwort, 8 parts of brocade lanterns, 6 parts of dendrobium, 5 parts of momordica and 3 parts of liquorice.
[0025] The inventor has found that the cause of laryngeal paralysis is that the six exogenous pathogens invade the human body's skin and skin, and the pathogenic heat is internal, so it invades the throat, or there is heat accumulation in the lungs and stomach, and the surface pathogens are not resolved, and the internal and external entanglements are entangled, burning the throat. In the clinical treatment of acute laryngeal paralysis, the inventor uses drugs that are mostly heat-clearing, phlegm-resolving, and throat-relieving. After long-term research, the drug properties of various drugs are fully mastered, thereby proposing the present invention. Clinical experiments have proved that the Chinese medicine composition of the present invention has a good therapeutic effect on laryngeal paralysis patients, especially acute pharyngitis, and the patient has no obvious adverse reactions during the treatment process.
[0026] In the Chinese medicine composition provided by the present invention, the compatibility mechanism of each component is as follows:
[0027] The main medicine in the prescription is the bitter and cold Scutellaria baicalensis, which is used to purge fire, and the pungent and astringent Fagopyrum truncatum, which is used to detoxify, directly reduce the heat of the lung and stomach. The minister uses the bitter and cold Fritillaria thunbergii to clear heat and resolve phlegm, detoxify, disperse knots and eliminate carbuncle; the bitter and slightly cold loquat leaf is good at treating stomach heat, vomiting, irritability and thirst; the slightly bitter and slightly cold Polygonum cuspidatum is good at clearing heat and detoxifying, dispersing blood stasis and relieving pain; the sweet, bitter and salty Scrophularia ningpoensis is good at clearing heat and cooling blood, nourishing yin and reducing fire, detoxifying and dispersing knots, and is good at treating febrile diseases that damage yin, red tongue and thirst, fluid damage constipation, and sore throat. The bitter and cold Lantern is good at treating sore throat and hoarseness; Dendrobium can benefit the stomach and produce fluid, nourish yin and clear heat, and is good at treating febrile diseases that damage fluid, dry mouth and thirst. The assistant medicine Momordica grosvenori can clear heat and moisten the lungs, relieve sore throat and open the voice; Licorice can both clear heat and detoxify and harmonize the various medicines. The combination of these medicines can clear away heat and detoxify, relieve sore throat and reduce swelling, and can solve the problems of sore throat, dry throat and burning sensation in the throat.
[0028] In a second aspect, the present invention provides a use of the throat-relieving Chinese medicinal composition as described in the first aspect in the preparation of a medicament for treating acute pharyngitis.
[0029] In a third aspect, the present invention provides a throat-relieving pharmaceutical preparation, which comprises the effective ingredients of the traditional Chinese medicine composition as described in the first aspect.
[0030] In some embodiments of the present invention, the pharmaceutical preparation further comprises an excipient.
[0031] In some embodiments of the present invention, the dosage form of the pharmaceutical preparation is tablets, capsules, granules or oral liquid.
[0032] In a fourth aspect, the present invention provides a method for preparing the pharmaceutical preparation according to the third aspect, the preparation method comprising the following steps:
[0033] (1) extracting the throat-relieving Chinese medicine composition according to the first aspect with water to obtain a water extract;
[0034] (2) preparing the aqueous extract into the dosage form of the pharmaceutical preparation.
[0035] In some embodiments of the present invention, during the water extraction in step (1), the amount of water used is 1-5 times the mass of the throat-relieving Chinese medicine composition; for example, it can be 1 time, 1.5 times, 2 times, 2.5 times, 3 times, 3.5 times, 4 times, 4.5 times or 5 times, etc. However, the present invention is not limited to the listed values, and other values not listed within the range are also applicable.
[0036] In some embodiments of the present invention, the water extraction method in step (1) is: decocting at least 2 times (for example, 2 times, 3 times, 4 times, 5 times, etc.), and decocting for 20-60 minutes (for example, 20 minutes, 25 minutes, 30 minutes, 35 minutes, 40 minutes, 45 minutes, 50 minutes, 55 minutes or 60 minutes, etc.) after the water boils each time. However, the present invention is not limited to the listed values, and other values not listed in the range are also applicable.
[0037] Compared with the prior art, the present invention has the following beneficial effects:
[0038] 1. The throat-relieving Chinese medicine composition provided by the present invention is scientifically compatible with golden buckwheat, scutellaria, thunbergia thunbergii, loquat leaves, polygonum cuspidatum, figwort, lantern, dendrobium, momordica grosvenori and liquorice, which can achieve the effects of clearing away heat and detoxifying, relieving throat and reducing swelling, has a good therapeutic effect on acute pharyngitis, and the patient has no obvious adverse reactions during the treatment process.
[0039] 2. The pharmaceutical preparation provided by the present invention has a simple prescription, a simple production process, few toxic and side effects, and is convenient to administer. The preparation is easy to manufacture and has low cost. DETAILED DESCRIPTION
[0040] The technical solution of the present invention is further described below by means of specific implementation methods. It should be understood by those skilled in the art that the specific implementation methods are only used to help understand the present invention and should not be regarded as specific limitations of the present invention.
[0041] Example 1
[0042] The present embodiment provides a throat-relieving Chinese medicine composition, comprising the following components in parts by weight:
[0043] 4 parts of golden buckwheat, 13 parts of scutellaria, 2 parts of thunbergia thunbergii, 12 parts of loquat leaves, 2 parts of knotweed, 12 parts of figwort, 4 parts of brocade lantern, 10 parts of dendrobium, 2 parts of momordica and 5 parts of liquorice.
[0044] This embodiment also provides a throat-clearing decoction, the preparation method of which is as follows:
[0045] According to the ratio of the throat-relieving Chinese medicine composition provided in this embodiment, 4 g of golden buckwheat, 13 g of scutellaria, 2 g of thunbergia, 12 g of loquat leaf, 2 g of polygonum cuspidatum, 12 g of figwort, 4 g of brocade lantern, 10 g of dendrobium, 2 g of momordica and 5 g of liquorice were taken, water was added until it was about 3 cm higher than the raw materials, soaked for 30 minutes, decocted twice, the first decocting time was 30 minutes after the water boiled, the second time used less water than the first time, and the decocting time was 20 minutes after the water boiled, and the two medicinal liquids were combined to obtain 400 mL of throat-relieving decoction.
[0046] Example 2
[0047] The present embodiment provides a throat-relieving Chinese medicine composition, comprising the following components in parts by weight:
[0048] 12 parts of golden buckwheat, 5 parts of scutellaria, 10 parts of thunbergia thunbergii, 4 parts of loquat leaves, 10 parts of knotweed, 4 parts of figwort, 12 parts of brocade lanterns, 2 parts of dendrobium, 8 parts of momordica and 1 part of liquorice.
[0049] This embodiment also provides a throat-clearing decoction, the preparation method of which is as follows:
[0050] According to the ratio of the throat-relieving Chinese medicine composition provided in this embodiment, 12g of golden buckwheat, 5g of scutellaria, 10g of thunbergia, 4g of loquat leaf, 10g of knotweed, 4g of scrophularia, 12g of lantern, 2g of dendrobium, 8g of momordica and 1g of liquorice were taken, water was added to about 3cm higher than the raw materials, soaked for 30 minutes, decocted twice, the first decocting time was decocted for 30 minutes after the water boiled, the second time used less water than the first time, and the decocting time was decocted for 20 minutes after the water boiled, and the two medicinal liquids were combined to obtain 400mL of throat-relieving decoction.
[0051] Example 3
[0052] The present embodiment provides a throat-relieving Chinese medicine composition, comprising the following components in parts by weight:
[0053] 6 parts of golden buckwheat, 11 parts of scutellaria, 4 parts of thunbergia thunbergii, 10 parts of loquat leaves, 4 parts of polygonum cuspidatum, 10 parts of figwort, 6 parts of brocade lanterns, 8 parts of dendrobium, 3.5 parts of momordica grosvenori and 4 parts of liquorice.
[0054] This embodiment also provides a throat-clearing decoction, the preparation method of which is as follows:
[0055] According to the ratio of the throat-relieving Chinese medicine composition provided in this embodiment, 6 g of golden buckwheat, 11 g of scutellaria, 4 g of thunbergia, 10 g of loquat leaf, 4 g of polygonum cuspidatum, 10 g of figwort, 6 g of brocade lantern, 8 g of dendrobium, 3.5 g of momordica grosvenori and 4 g of liquorice were taken, water was added until it was about 3 cm higher than the raw materials, soaked for 30 minutes, decocted twice, the first decocting time was 30 minutes after the water boiled, the second time used less water than the first time, and the decocting time was 20 minutes after the water boiled, and the two medicinal liquids were combined to obtain 400 mL of throat-relieving decoction.
[0056] Example 4
[0057] The present embodiment provides a throat-relieving Chinese medicine composition, comprising the following components in parts by weight:
[0058] 10 parts of golden buckwheat, 7 parts of scutellaria, 8 parts of thunbergia thunbergii, 6 parts of loquat leaves, 8 parts of polygonum cuspidatum, 6 parts of figwort, 10 parts of lanterns, 4 parts of dendrobium, 6.5 parts of momordica and 2 parts of liquorice.
[0059] This embodiment also provides a throat-clearing decoction, the preparation method of which is as follows:
[0060] According to the ratio of the throat-relieving Chinese medicine composition provided in this embodiment, 10g of golden buckwheat, 7g of scutellaria, 8g of thunbergia, 6g of loquat leaf, 8g of polygonum cuspidatum, 6g of figwort, 10g of lantern lantern, 4g of dendrobium, 6.5g of momordica grosvenori and 2g of liquorice were taken, water was added until it was about 3cm higher than the raw materials, soaked for 30 minutes, decocted twice, the first decocting time was decocted for 30 minutes after the water boiled, the second time used less water than the first time, and the decocting time was decocted for 20 minutes after the water boiled, and the two medicinal liquids were combined to obtain 400mL of throat-relieving decoction.
[0061] Example 5
[0062] The present embodiment provides a throat-relieving Chinese medicine composition, comprising the following components in parts by weight:
[0063] 8 parts of golden buckwheat, 9 parts of scutellaria, 6 parts of thunbergia thunbergii, 8 parts of loquat leaves, 6 parts of polygonum cuspidatum, 8 parts of figwort, 8 parts of brocade lanterns, 6 parts of dendrobium, 5 parts of momordica and 3 parts of liquorice.
[0064] This embodiment also provides a throat-clearing decoction, the preparation method of which is as follows:
[0065] According to the ratio of the throat-relieving Chinese medicine composition provided in this embodiment, 8g of golden buckwheat, 9g of scutellaria, 6g of thunbergia, 8g of loquat leaf, 6g of polygonum cuspidatum, 8g of figwort, 8g of brocade lantern, 6g of dendrobium, 5g of momordica and 3g of liquorice were taken, water was added to about 3cm higher than the raw materials, soaked for 30 minutes, decocted twice, the first decocting time was decocted for 30 minutes after the water boiled, the second time used less water than the first time, and the decocting time was decocted for 20 minutes after the water boiled, and the two medicinal liquids were combined to obtain 400mL of throat-relieving decoction.
[0066] 1. Clinical efficacy test
[0067] Retrospective analysis was conducted to screen out patients with acute pharyngitis that met the Western medical diagnostic criteria and whose TCM syndrome type was lung and stomach heat from the respiratory department of a certain hospital, and to evaluate the therapeutic effect of the drug of the present invention on acute pharyngitis.
[0068] Control group: 30 cases, oral administration of Lanqin oral liquid, specification: 10mL, manufacturer: Yangtze River Pharmaceutical Group Co., Ltd. Main ingredients: Radix Isatidis, Radix Scutellariae, Fructus Gardeniae, Cortex Phellodendri, Fructus Sterculiae. 3 times a day, 10mL (1 bottle) each time, half an hour after meals, 5 days as a course of treatment, a total of 1 course of treatment.
[0069] Treatment group: 30 cases, orally took the throat-clearing decoction provided in Example 5 of the present invention, twice a day, 200 mL each time, half an hour after a meal, 5 days as one course of treatment, a total of one course of treatment.
[0070] 2. Clinical efficacy evaluation criteria:
[0071] 2.1 Symptom score
[0072] Clinical symptoms of sore throat, dry throat, and burning sensation in the throat were scored using VAS, and the sum of the scores of each symptom was calculated as the main reference indicator for evaluating clinical efficacy. The score ranged from 0 to 10, with 0 being the mildest and 10 being the most severe.
[0073] 2.2 Physical sign scoring
[0074] The physical sign scoring adopts the grading standard, with a score of 0-3 points, which is a secondary reference indicator. The clinical sign scoring standard is shown in Table 1.
[0075] Table 1
[0076]
[0077] 2.3. Efficacy Index
[0078] Therapeutic index N = (difference in total symptom scores before and after treatment ÷ total symptom scores before treatment) × 100%;
[0079] Cured: Symptoms such as sore throat, dry throat, and burning sensation in the throat completely disappear N ≥ 90%;
[0080] Significantly effective: symptoms such as sore throat, dry throat, and burning sensation in the throat basically disappeared 66.67%≤N<90%;
[0081] Effective: Symptoms such as sore throat, dry throat, and burning sensation in the throat were alleviated by 33.33%≤N<66.67%;
[0082] Ineffective: There was no significant improvement in symptoms such as sore throat, dry throat, and burning sensation in the throat. N<33.33%.
[0083] 3. Treatment results
[0084] 3.1 Symptom score
[0085] The symptom scores of the control group and the treatment group before and after treatment are shown in Table 2.
[0086] Table 2
[0087]
[0088]
[0089] In the table, * indicates comparison with the control group, p<0.05.
[0090] The results of the t-test are as follows:
[0091] (1) The symptom scores of the two groups before treatment were similar in terms of pharyngeal pain, dry throat, and pharyngeal burning sensation, P>0.05, indicating that the symptom scores of the two groups before treatment were comparable.
[0092] (2) After treatment, the symptom scores of the two groups were significantly different in terms of sore throat and burning sensation in the throat (P<0.05), indicating that the treatment group was better than the control group in treating sore throat and burning sensation in acute pharyngitis. In terms of dry throat, P>0.05, there was no significant difference in the treatment effect of the treatment group on dry throat compared with the control group.
[0093] (3) Comparison of the total symptom scores between the two groups after treatment showed a significant difference (p<0.05), indicating that the treatment group was better than the control group in the treatment of acute pharyngitis.
[0094] 3.2 Physical sign scoring
[0095] The physical sign scores of the control group and the treatment group before and after treatment are shown in Table 3.
[0096] Table 3
[0097] Group Before treatment After treatment Treatment Group 1.83±0.53 0.60±0.67* Control group 1.76±0.50 1.00±0.74
[0098] In the table, * indicates comparison with the control group, p<0.05.
[0099] The results of the t-test are as follows:
[0100] (1) The physical sign scores of the two groups before treatment were P>0.05. This showed that there was no difference in the physical sign scores of the two groups before treatment and they were comparable.
[0101] (2) There was a significant difference in the physical sign scores between the two groups after treatment (p<0.05), indicating that the treatment group was more effective than the control group in treating acute pharyngitis and pharyngeal congestion.
[0102] 3.3 Therapeutic index
[0103] No obvious adverse reactions occurred in the treatment group or the control group during medication.
[0104] The efficacy indexes of the control group and the treatment group after treatment are shown in Table 4.
[0105] Table 4
[0106] Group Number of cases cure Significant effect efficient invalid Treatment Group 30 3(10.00%) 21(70.00%) 5(16.67%) 1(3.33%) Control group 30 1(3.33%) 12(40.00%) 14(46.67%) 3(10.00%)
[0107] It can be seen from the data in Tables 2 to 4 that after treatment, the symptom scores and sign scores of the patients in the treatment group were lower than those of the patients in the control group, and the cure rate and significant efficacy of the treatment group were better than those of the control group, indicating that the throat-relieving Chinese medicine composition and pharmaceutical preparation provided by the present invention can effectively treat acute pharyngitis, and the therapeutic effect is better than that of Lanqin oral liquid.
[0108] The above description is only a specific embodiment of the present disclosure, so that those skilled in the art can understand or implement the present disclosure. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present disclosure. Therefore, the present disclosure will not be limited to the embodiments described herein, but will conform to the widest scope consistent with the principles and novel features disclosed herein.
Claims
1. A Chinese medicine composition for relieving throat pain, characterized in that: The throat-relieving Chinese medicine composition comprises the following components: Fagopyrum scabra, Scutellaria baicalensis, Fritillaria thunbergii, loquat leaf, Polygonum cuspidatum, Scrophularia ningpoensis, Lantern Festival, Dendrobium candidum, Momordica grosvenori and Licorice.
2. The throat-relieving Chinese medicine composition according to claim 1, characterized in that: The throat-relieving Chinese medicine composition comprises the following components in parts by weight: 4-12 parts of golden buckwheat, 5-13 parts of scutellaria, 2-10 parts of thunbergia thunbergii, 4-12 parts of loquat leaves, 2-10 parts of knotweed, 4-12 parts of figwort, 4-12 parts of lanterns, 2-10 parts of dendrobium, 2-8 parts of momordica grosvenori and 1-5 parts of liquorice.
3. The throat-relieving Chinese medicine composition according to claim 1 or 2, characterized in that: The throat-relieving Chinese medicine composition comprises the following components in parts by weight: 6-10 parts of golden buckwheat, 7-11 parts of scutellaria, 4-8 parts of thunbergii, 6-10 parts of loquat leaves, 4-8 parts of knotweed, 6-10 parts of figwort, 6-10 parts of lanterns, 4-8 parts of dendrobium, 3.5-6.5 parts of momordica and 2-4 parts of liquorice.
4. The throat-relieving Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The throat-relieving Chinese medicine composition comprises the following components in parts by weight: 8 parts of golden buckwheat, 9 parts of scutellaria, 6 parts of thunbergia thunbergii, 8 parts of loquat leaves, 6 parts of polygonum cuspidatum, 8 parts of figwort, 8 parts of brocade lanterns, 6 parts of dendrobium, 5 parts of momordica and 3 parts of liquorice.
5. Use of the throat-relieving Chinese medicinal composition according to any one of claims 1 to 4 in the preparation of a medicament for treating acute pharyngitis.
6. A throat-relieving drug preparation, characterized in that: The pharmaceutical preparation comprises the effective ingredients of the throat-relieving Chinese medicine composition according to any one of claims 1 to 4.
7. The pharmaceutical preparation according to claim 6, characterized in that The pharmaceutical preparation further includes an excipient.
8. The pharmaceutical preparation according to claim 6 or 7, characterized in that The dosage form of the pharmaceutical preparation is tablet, capsule, granule or oral solution.
9. A method for preparing a pharmaceutical preparation according to any one of claims 6 to 8, characterized in that: The preparation method comprises the following steps: (1) extracting the throat-relieving Chinese medicine composition according to any one of claims 1 to 4 with water to obtain a water extract; (2) preparing the aqueous extract into the dosage form of the pharmaceutical preparation.
10. The preparation method according to claim 9, characterized in that: When the water extraction is performed in step (1), the amount of water used is 1-5 times the mass of the throat-relieving Chinese medicine composition; Preferably, the water extraction method in step (1) is: decocting at least twice, each time decocting for 20-60 minutes after the water boils.