Formula and preparation method of granules for softening hardness to dissipate stagnation

Abstract

The invention discloses a formula of granules for softening hardness to dissipate stagnation. The traditional Chinese medicine is prepared from the following raw materials: 10 to 50g of spica prunellae, 10 to 15g of rhizoma curcumae, 10 to 30g of bulbus fritillariae thunbergii, 10 to 20g of spina gleditsiae, 10 to 20g of edible tulip, 10 to 30g of radix scrophulariae, 4 to 13g of ginger processed pinellia, 4 to 13g of frankincense, 4 to 13g of myrrh, 10 to 90g of radix paeoniae alba, 10 to 14g of myrcia, 2 to 12g of roasted ephedra, 2 to 12g of vinegar tortoise shell, 10 to 20g of raw dragon bone and oyster shell, 10 to 20g of ginseng, 10 to 30g of radix clematidis, 8 to 13g of fructus crataegi, 3 to 9g of rhizoma polygoni cuspidati, 3 to 9g of rhizoma corydalis, 3 to 5g of herba menthae, 3 The invention relates to the technical field of hard lump resolving particles. According to the formula and the preparation method of the hard lump-resolving granules, the effects of softening hard lumps, diminishing swelling, dredging collaterals and resolving masses are achieved, and nodules, goiter and breast nuclei caused by phlegm and blood stasis and qi-blood arthralgia dampness can be treated. The purpose of transforming tumor cells into normal cells is achieved, and the drug treatment effect is improved.

Description

Technical Field

[0001] The invention relates to the technical field of softening and dispersing granules, and in particular to a formula of softening and dispersing granules and a preparation method thereof. Background Art

[0002] Sarcoidosis is a multi-organ disease, often invading the lungs, lymph nodes, skin, liver, eyes, spleen, bones, parotid glands and heart. Physical examinations found that about 40.9% of patients were accompanied by symptoms. Symptoms include weight loss, fatigue, weakness, fever, dry cough, less sputum, shortness of breath, chest pain, hemoptysis, etc. About 1 / 4 of the cases have eye or skin lesions. Eye diseases include iridocyclitis, acute chromatosis, keratoconjunctivitis, cataracts, glaucoma, etc. The most common skin lesion is erythema nodosum (accounting for about 1 / 3 of the skin lesions). It is common on the face, neck, shoulders or limbs, and there are also chilblain-like lupus, macules, papules, etc. The parotid glands are enlarged, the liver and spleen are enlarged, the facial nerve is paralyzed, and the superficial lymph nodes are enlarged. In sarcoid myocarditis, there may be arrhythmias, conduction blocks, ventricular aneurysms, and multiple arthritis. Cystic changes in the phalanges are seen in 5-10% of cases. In the past, it was believed that less than 1% of patients had pleural effusion, but recent statistics show that up to 10% of patients have pleural effusion. It is more common in chronic cases with multiple organ invasion. There may be a small amount of interlobar pleural effusion. The incidence of sarcoidosis varies greatly around the world. It is more common in cold regions and countries and less common in tropical regions. The first case was reported in my country in 1958, and by 1991, more than 400 cases had been reported nationwide.

[0003] There are many drugs for the treatment of sarcoidosis, including Chinese medicine and Western medicine. Since the drugs directly kill tumor cells and cannot transform tumor cells into normal cells, their efficacy is not satisfactory. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a formula for softening and dispersing granules and a preparation method thereof, which solve the above-mentioned problems.

[0005] To achieve the above purpose, the present invention is achieved through the following technical scheme: a formula for softening and dispersing granules, composed of the following raw materials: 10-50g of Prunella Vulgaris, 10-15g of Curcuma, 10-30g of Fritillaria Thunbergii, 10-20g of Sophora flavescens, 10-20g of Trillium, 10-20g of Scrophularia ningpoensis, 4-13g of Pinellia ternata, 4-13g of Frankincense, 4-13g of Myrrh, 10-90g of White Peony Root, 10-14g of Bay Leaf, 2-12g of Ephedra sinica, 2-12g of Vinegar Tortoise Shell, 10-20g of Raw Dragon and Oyster Mud, 10-20g of Ginseng, 10-30g of Clematis, 8-13g of Hawthorn, 3-9g of Polygonum cuspidatum, 3-9g of Corydalis, 3-5g of Menthus, 3-9g of Burdock Root, 1-3g of Poria and 10-14g of Smilax glabra.

[0006] Preferably, a formula for softening and dispersing granules is composed of the following raw materials: 30g of Prunella Vulgaris, 12g of Curcuma, 20g of Fritillaria Thunbergii, 15g of Sophora flavescens, 15g of Trillium, 20g of Scrophularia ningpoensis, 9g of Pinellia ternata, 9g of Frankincense, 9g of Myrrh, 50g of White Peony Root, 12g of Bay Leaf, 7g of Ephedra sinica, 2g of Vinegar Tortoise Shell, 15g of Raw Dragon and Oyster Mud, 15g of Ginseng, 20g of Clematis, 11g of Hawthorn, 6g of Polygonum cuspidatum, 6g of Corydalis yanhusuo, 4g of Menthus, 6g of Burdock Root, 2g of Poria and 12g of Smilax glabra.

[0007] A method for preparing a hardness softening and dispersing granule formula, comprising the following steps: Step 1, prepare the materials, weigh Prunella Vulgaris, Curcuma, Fritillaria Thunbergii, Sophora japonica, Psoralea corylifolia, Scrophularia ningpoensis, Pinellia ternata, frankincense, myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, Poria cocos and tongcao according to the proportion; Step 2: Remove weeds and clean. Remove weeds on the surface of Prunella Vulgaris, clean and dry it for later use; it can clear the liver and reduce fire, improve eyesight, disperse lumps and reduce swelling.

[0008] Select and dig up the roots of Curcuma zedoaria, remove the soil on the rhizomes, wash and dry them for later use; it can promote qi and resolve blood, eliminate accumulation and relieve pain; it can be used for heart pain due to blood and qi, food stagnation, abdominal distension and pain, blood stasis, amenorrhea, dysmenorrhea, lumps and masses, and injuries from falls.

[0009] Wash the Fritillaria thunbergii, cut into sections, dry in the sun and set aside; bitter in taste; cold in nature. Meridians: Lung and Heart Meridians.

[0010] Remove impurities from soapberry; soak uncut ones briefly, moisten thoroughly, cut into thick slices, wash and dry for later use; disinfect and remove pus; remove wind; kill insects. It is used to treat carbuncle, swelling, scrofula, sores, stubborn ringworms, lack of milk after childbirth, retained placenta, and leprosy.

[0011] Remove impurities from Trillium gracile, soak in water, pick up, moisten thoroughly, slice, dry, and set aside; it has the effects of relieving asthma and cough, relieving pain, and anti-cancer, and can be used to treat bronchitis, asthma, breast cancer, nasopharyngeal cancer and other tumors Pick out impurities from Scrophularia, remove the rhizome, wash and soak, slice, and dry; for febrile diseases, heat enters the blood; fever; thirst; red tongue; spots; bone steaming and fatigue cough; insomnia; constipation due to loss of body fluid; dry and blurred vision; sore throat; scrofula and phlegm nodules; carbuncles and ulcers.

[0012] Sift the ginger and pinellia to remove dust, wash and dry for later use; use it for cough and asthma due to excessive phlegm, dizziness and palpitations caused by phlegm and fluid, dizziness caused by wind and phlegm, headache caused by phlegm, vomiting and nausea, chest and abdominal distension, and plum pit qi; use it raw for external treatment of carbuncles, swellings and phlegm nodules.

[0013] Vinegar-fried frankincense is a method of stir-frying frankincense by adding a certain amount of rice vinegar to the cleaned or cut medicine until the surface is shiny. It is used for chest pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to masses, rheumatic pain, tendon and vein spasm, bruises, carbuncles and ulcers.

[0014] Sift myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao to remove dust, wash and dry for later use; Step 3: Soaking the raw materials: adding all the dried grass, zedoaria, fritillaria thunbergii, soapberry, trillium, scrophularia, pinellia ternata and frankincense into a first soaking bucket, and adding clean water into the bucket to soak the materials; Step 4, concentration and extraction, the raw materials soaked in the first soaking barrel in step 3 are added to a crusher, the materials are chopped into particles, the mixed particle raw materials are put into a heating container, and clean water is added to soak, so that the clean water covers the top of the raw materials, the heating container heats the materials to boil, and after boiling, a low fire is turned on to continue boiling, the boiled materials are separated into solid and liquid, and the separated liquid is added to a centrifuge to centrifuge and filter the solid impurities to obtain a concentrated material; Step 5, add myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao as auxiliary materials into the grinder and grind and crush; Step 6: Add the mixed auxiliary materials ground and crushed in step 5 into the second soaking bucket, and soak them in clean water. After soaking, heat the storage container until it boils, stir the materials continuously during the boiling process, and then filter the liquid to obtain a filtrate; Step 7: Evenly mix the concentrated solution obtained in step 4 and the filtrate obtained in step 6, and then filter out impurities by centrifugation; Step 8, boiling and concentrating the mixed medicine again to form a thick paste; Step 9: The obtained thick paste is made into wet granules by a granulator, and then the granules are dried.

[0015] Preferably, the temperature of the clean water added to the first soaking barrel in step three is 90°C.

[0016] Preferably, in step three, after adding clean water into the first soaking bucket, use a shovel to stir the raw materials along the edge of the bucket to the center of the bucket so that the water level is 20 cm above the surface of the material.

[0017] Preferably, in step three, the water temperature in the first soaking barrel is maintained at 75° C.-80° C., and the soaking time is 8-12 hours.

[0018] Preferably, in step five, the auxiliary material is crushed to 10-30 mesh.

[0019] Preferably, in step eight, the concentrate is concentrated to a relative density of 1.2-1.3.

[0020] Preferably, after drying in step nine, the granules are sieved with a 10-12 mesh screen.

[0021] The present invention provides a formula for softening and dispersing granules and a preparation method thereof. The formula has the following beneficial effects: the main ingredients are: tortoise shell with vinegar and Prunella vulgaris; the auxiliary ingredients are: Curcuma zedoaria, frankincense, myrrh, Sophora flavescens, Fritillaria thunbergii, Pinellia ternata, Tripterygium wilfordii; the auxiliary ingredients are: Scrophularia ningpoensis, ginseng, white peony root, bay leaf; the envoys are: Clematidis and roasted ephedra, and the main effects are softening and relieving swelling, unblocking meridians and dispersing granules, and the granules can be used to treat nodules, goiters, and breast nodules caused by phlegm and blood stasis, and qi and blood stasis and dampness. The purpose of transforming tumor cells into normal cells is achieved, and the drug treatment effect is improved. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Example

[0023] The invention provides a technical scheme: a formula of softening and dispersing granules, which is composed of the following raw materials: 10g of Prunella Vulgaris, 10g of Curcuma Atractylodes, 10g of Fritillaria Thunbergii, 10g of Sophora japonica, 10g of Tripterygium wilfordii, 10g of Scrophularia ningpoensis, 4g of Pinellia ternata, 4g of Olibanum incense, 4g of Myrrha, 10g of White Peony Root, 10g of Bay Leaf, 2g of Ephedra sinica, 2g of Vinegar Tortoise Shell, 10g of Raw Dragon and Oyster Mud, 10g of Ginseng, 10g of Clematis, 8g of Crataegus pinnatifida, 3g of Polygonum cuspidatum, 3g of Rhizoma Corydalis, 3g of Mentha, 3g of Burdock Root, 1g of Poria and 10g of Smilax glabra.

[0024] A method for preparing a hardness softening and dispersing granule formula, comprising the following steps: Step 1, prepare the materials, weigh Prunella Vulgaris, Curcuma, Fritillaria Thunbergii, Sophora japonica, Psoralea corylifolia, Scrophularia ningpoensis, Pinellia ternata, frankincense, myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, Poria cocos and tongcao according to the proportion; Step 2: Remove weeds and clean. Remove weeds on the surface of Prunella Vulgaris, clean and dry it for later use; it can clear the liver and reduce fire, improve eyesight, disperse lumps and reduce swelling.

[0025] Select and dig up the roots of Curcuma zedoaria, remove the soil on the rhizomes, wash and dry them for later use; it can promote qi and resolve blood, eliminate accumulation and relieve pain; it can be used for heart pain due to blood and qi, food stagnation, abdominal distension and pain, blood stasis, amenorrhea, dysmenorrhea, lumps and masses, and injuries from falls.

[0026] Wash the Fritillaria thunbergii, cut into sections, dry in the sun and set aside; bitter in taste; cold in nature. Meridians: Lung and Heart Meridians.

[0027] Remove impurities from soapberry; soak uncut ones briefly, moisten thoroughly, cut into thick slices, wash and dry for later use; disinfect and remove pus; remove wind; kill insects. It is used to treat carbuncle, swelling, scrofula, sores, stubborn ringworms, lack of milk after childbirth, retained placenta, and leprosy.

[0028] Remove impurities from Trillium gracile, soak in water, pick up, moisten thoroughly, slice, dry, and set aside; it has the effects of relieving asthma and cough, relieving pain, and anti-cancer, and can be used to treat bronchitis, asthma, breast cancer, nasopharyngeal cancer and other tumors Pick out impurities from Scrophularia, remove the rhizome, wash and soak, slice, and dry; for febrile diseases, heat enters the blood; fever; thirst; red tongue; spots; bone steaming and fatigue cough; insomnia; constipation due to loss of body fluid; dry and blurred vision; sore throat; scrofula and phlegm nodules; carbuncles and ulcers.

[0029] Sift the ginger and pinellia to remove dust, wash and dry for later use; use it for cough and asthma due to excessive phlegm, dizziness and palpitations caused by phlegm and fluid, dizziness caused by wind and phlegm, headache caused by phlegm, vomiting and nausea, chest and abdominal distension, and plum pit qi; use it raw for external treatment of carbuncles, swellings and phlegm nodules.

[0030] Vinegar-fried frankincense is a method of stir-frying frankincense by adding a certain amount of rice vinegar to the cleaned or cut medicine until the surface is shiny. It is used for chest pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to masses, rheumatic pain, tendon and vein spasm, bruises, carbuncles and ulcers.

[0031] Sift myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao to remove dust, wash and dry for later use; Step 3: Soaking the raw materials: adding all the dried grass, zedoaria, fritillaria thunbergii, soapberry, trillium, scrophularia, pinellia ternata and frankincense into a first soaking bucket, and adding clean water into the bucket to soak the materials; Step 4, concentration and extraction, the raw materials soaked in the first soaking barrel in step 3 are added to a crusher, the materials are chopped into particles, the mixed particle raw materials are put into a heating container, and clean water is added to soak, so that the clean water covers the top of the raw materials, the heating container heats the materials to boil, and after boiling, a low fire is turned on to continue boiling, the boiled materials are separated into solid and liquid, and the separated liquid is added to a centrifuge to centrifuge and filter the solid impurities to obtain a concentrated material; Step 5, add myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao as auxiliary materials into the grinder and grind and crush the auxiliary materials into 10 mesh; Step 6: Add the mixed auxiliary materials ground and crushed in step 5 into the second soaking bucket, and soak them in clean water. After soaking, heat the storage container until it boils, stir the materials continuously during the boiling process, and then filter the liquid to obtain a filtrate; Step 7: Evenly mix the concentrated solution obtained in step 4 and the filtrate obtained in step 6, and then filter out impurities by centrifugation; Step 8, decoct and concentrate the mixed medicine again to form a thick paste with a relative density of 1.2; Step 9: Use a granulator to make wet granules from the obtained thick paste, then dry the granules, and then use a 10-12 mesh sieve to sieve the granules after drying.

[0032] In step 3, the temperature of the clean water added to the first soaking bucket is 90°C.

[0033] In step 3, add clean water to the first soaking bucket and use a shovel to stir the raw materials along the edge of the bucket to the center of the bucket so that the water level is 20 cm above the surface of the material.

[0034] In step 3, the water temperature in the first soaking bucket is maintained at 75° C. and the soaking time is 8 hours. Example

[0035] The invention provides a technical scheme: a formula of softening and dispersing granules, which is composed of the following raw materials: 30g of Prunella Vulgaris, 12g of Curcuma Atractylodes, 20g of Fritillaria Thunbergii, 15g of Sophora japonica, 15g of Tripterygium wilfordii, 20g of Scrophularia ningpoensis, 9g of Pinellia ternata, 9g of Olibanum incense, 9g of Myrrha, 50g of White Peony Root, 12g of Bay Leaf, 7g of Ephedra sinica with moxibustion, 2g of Vinegar-scented Tortoise Shell, 15g of Raw Dragon and Oyster Mud, 15g of Ginseng, 20g of Clematis, 11g of Hawthorn, 6g of Polygonum cuspidatum, 6g of Rhizoma Corydalis, 4g of Menthus fragrans, 6g of Burdock Root, 2g of Poria and 12g of Smilax glabra.

[0036] A method for preparing a hardness softening and dispersing granule formula, comprising the following steps: Step 1, prepare the materials, weigh Prunella Vulgaris, Curcuma, Fritillaria Thunbergii, Sophora japonica, Psoralea corylifolia, Scrophularia ningpoensis, Pinellia ternata, frankincense, myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, Poria cocos and tongcao according to the proportion; Step 2: Remove weeds and clean. Remove weeds on the surface of Prunella Vulgaris, clean and dry it for later use; it can clear the liver and reduce fire, improve eyesight, disperse lumps and reduce swelling.

[0037] Select and dig up the roots of Curcuma zedoaria, remove the soil on the rhizomes, wash and dry them for later use; it can promote qi and resolve blood, eliminate accumulation and relieve pain; it can be used for heart pain due to blood and qi, food stagnation, abdominal distension and pain, blood stasis, amenorrhea, dysmenorrhea, lumps and masses, and injuries from falls.

[0038] Wash the Fritillaria thunbergii, cut into sections, dry in the sun and set aside; bitter in taste; cold in nature. Meridians: Lung and Heart Meridians.

[0039] Remove impurities from soapberry; soak uncut ones briefly, moisten thoroughly, cut into thick slices, wash and dry for later use; disinfect and remove pus; remove wind; kill insects. It is used to treat carbuncle, swelling, scrofula, sores, stubborn ringworms, lack of milk after childbirth, retained placenta, and leprosy.

[0040] Remove impurities from Trillium gracile, soak in water, pick up, moisten thoroughly, slice, dry, and set aside; it has the effects of relieving asthma and cough, relieving pain, and anti-cancer, and can be used to treat bronchitis, asthma, breast cancer, nasopharyngeal cancer and other tumors Pick out impurities from Scrophularia, remove the rhizome, wash and soak, slice, and dry; for febrile diseases, heat enters the blood; fever; thirst; red tongue; spots; bone steaming and fatigue cough; insomnia; constipation due to loss of body fluid; dry and blurred vision; sore throat; scrofula and phlegm nodules; carbuncles and ulcers.

[0041] Sift the ginger and pinellia to remove dust, wash and dry for later use; use it for cough and asthma due to excessive phlegm, dizziness and palpitations caused by phlegm and fluid, dizziness caused by wind and phlegm, headache caused by phlegm, vomiting and nausea, chest and abdominal distension, and plum pit qi; use it raw for external treatment of carbuncles, swellings and phlegm nodules.

[0042] Vinegar-fried frankincense is a method of stir-frying frankincense by adding a certain amount of rice vinegar to the cleaned or cut medicine until the surface is shiny. It is used for chest pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to masses, rheumatic pain, tendon and vein spasm, bruises, carbuncles and ulcers.

[0043] Sift myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao to remove dust, wash and dry for later use; Step 3: Soaking the raw materials: adding all the dried grass, zedoaria, fritillaria thunbergii, soapberry, trillium, scrophularia, pinellia ternata and frankincense into a first soaking bucket, and adding clean water into the bucket to soak the materials; Step 4, concentration and extraction, the raw materials soaked in the first soaking barrel in step 3 are added to a crusher, the materials are chopped into particles, the mixed particle raw materials are put into a heating container, and clean water is added to soak, so that the clean water covers the top of the raw materials, the heating container heats the materials to boil, and after boiling, a low fire is turned on to continue boiling, the boiled materials are separated into solid and liquid, and the separated liquid is added to a centrifuge to centrifuge and filter the solid impurities to obtain a concentrated material; Step 5: Add myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao as auxiliary materials into the grinder and grind and crush the auxiliary materials into 20 mesh; Step 6: Add the mixed auxiliary materials ground and crushed in step 5 into the second soaking bucket, and soak them in clean water. After soaking, heat the storage container until it boils, stir the materials continuously during the boiling process, and then filter the liquid to obtain a filtrate; Step 7: Evenly mix the concentrated solution obtained in step 4 and the filtrate obtained in step 6, and then filter out impurities by centrifugation; Step 8, decoct and concentrate the mixed medicine again to form a thick paste, and concentrate it to a relative density of 1.25; Step 9: Use a granulator to make wet granules from the obtained thick paste, then dry the granules, and then use a 10-12 mesh sieve to sieve the granules after drying.

[0044] In step 3, the temperature of the clean water added to the first soaking bucket is 90°C.

[0045] In step 3, add clean water to the first soaking bucket and use a shovel to stir the raw materials along the edge of the bucket to the center of the bucket so that the water level is 20 cm above the surface of the material.

[0046] In step 3, the water temperature in the first soaking bucket is maintained at 78° C. and the soaking time is 10 hours. Example

[0047] The invention provides a technical scheme: a formula of softening and dispersing granules, which is composed of the following raw materials: 50g of Prunella Vulgaris, 15g of Curcuma Atractylodes, 30g of Fritillaria Thunbergii, 20g of Sophora flavescens, 20g of Tripterygium wilfordii, 30g of Scrophularia ningpoensis, 13g of Pinellia ternata, 13g of Olibanum incense, 13g of Myrrha, 90g of White Peony Root, 14g of Bay Leaf, 12g of Ephedra sinica with moxibustion, 12g of Tortoise Shell with Vinegar, 20g of Raw Dragon and Oyster Mud, 20g of Ginseng, 30g of Clematis, 13g of Hawthorn, 9g of Polygonum cuspidatum, 9g of Rhizoma Corydalis, 5g of Menthus fragrans, 9g of Burdock Root, 3g of Poria and 14g of Smilax glabra.

[0048] A method for preparing a hardness softening and dispersing granule formula, comprising the following steps: Step 1, prepare the materials, weigh Prunella Vulgaris, Curcuma, Fritillaria Thunbergii, Sophora japonica, Psoralea corylifolia, Scrophularia ningpoensis, Pinellia ternata, frankincense, myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, Poria cocos and tongcao according to the proportion; Step 2: Remove weeds and clean. Remove weeds on the surface of Prunella Vulgaris, clean and dry it for later use; it can clear the liver and reduce fire, improve eyesight, disperse lumps and reduce swelling.

[0049] Select and dig up the roots of Curcuma zedoaria, remove the soil on the rhizomes, wash and dry them for later use; it can promote qi and resolve blood, eliminate accumulation and relieve pain; it can be used for heart pain due to blood and qi, food stagnation, abdominal distension and pain, blood stasis, amenorrhea, dysmenorrhea, lumps and masses, and injuries from falls.

[0050] Wash the Fritillaria thunbergii, cut into sections, dry in the sun and set aside; bitter in taste; cold in nature. Meridians: Lung and Heart Meridians.

[0051] Remove impurities from soapberry; soak uncut ones briefly, moisten thoroughly, cut into thick slices, wash and dry for later use; disinfect and remove pus; remove wind; kill insects. It is used to treat carbuncle, swelling, scrofula, sores, stubborn ringworms, lack of milk after childbirth, retained placenta, and leprosy.

[0052] Remove impurities from Trillium gracile, soak in water, pick up, moisten thoroughly, slice, dry, and set aside; it has the effects of relieving asthma and cough, relieving pain, and anti-cancer, and can be used to treat bronchitis, asthma, breast cancer, nasopharyngeal cancer and other tumors Pick out impurities from Scrophularia, remove the rhizome, wash and soak, slice, and dry; for febrile diseases, heat enters the blood; fever; thirst; red tongue; spots; bone steaming and fatigue cough; insomnia; constipation due to loss of body fluid; dry and blurred vision; sore throat; scrofula and phlegm nodules; carbuncles and ulcers.

[0053] Sift the ginger and pinellia to remove dust, wash and dry for later use; use it for cough and asthma due to excessive phlegm, dizziness and palpitations caused by phlegm and fluid, dizziness caused by wind and phlegm, headache caused by phlegm, vomiting and nausea, chest and abdominal distension, and plum pit qi; use it raw for external treatment of carbuncles, swellings and phlegm nodules.

[0054] Vinegar-fried frankincense is a method of stir-frying frankincense by adding a certain amount of rice vinegar to the cleaned or cut medicine until the surface is shiny. It is used for chest pain, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to masses, rheumatic pain, tendon and vein spasm, bruises, carbuncles and ulcers.

[0055] Sift myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao to remove dust, wash and dry for later use; Step 3: Soaking the raw materials: adding all the dried grass, zedoaria, fritillaria thunbergii, soapberry, trillium, scrophularia, pinellia ternata and frankincense into a first soaking bucket, and adding clean water into the bucket to soak the materials; Step 4, concentration and extraction, the raw materials soaked in the first soaking barrel in step 3 are added to a crusher, the materials are chopped into particles, the mixed particle raw materials are put into a heating container, and clean water is added to soak, so that the clean water covers the top of the raw materials, the heating container heats the materials to boil, and after boiling, a low fire is turned on to continue boiling, the boiled materials are separated into solid and liquid, and the separated liquid is added to a centrifuge to centrifuge and filter the solid impurities to obtain a concentrated material; Step 5: Add myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao as auxiliary materials into the grinder and grind and crush the auxiliary materials into 20 mesh; Step 6: Add the mixed auxiliary materials ground and crushed in step 5 into the second soaking bucket, and soak them in clean water. After soaking, heat the storage container until it boils, stir the materials continuously during the boiling process, and then filter the liquid to obtain a filtrate; Step 7: Evenly mix the concentrated solution obtained in step 4 and the filtrate obtained in step 6, and then filter out impurities by centrifugation; Step 8, decoct and concentrate the mixed medicine again to form a thick paste, and concentrate it to a relative density of 1.25; Step 9: Use a granulator to make wet granules from the obtained thick paste, then dry the granules, and then use a 10-12 mesh sieve to sieve the granules after drying.

[0056] In step 3, the temperature of the clean water added to the first soaking bucket is 90°C.

[0057] In step 3, add clean water to the first soaking bucket and use a shovel to stir the raw materials along the edge of the bucket to the center of the bucket so that the water level is 20 cm above the surface of the material.

[0058] In step 3, the water temperature in the first soaking bucket is maintained at 78° C. and the soaking time is 10 hours.

[0059] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions. The sentence "includes an element defined by ... does not exclude the existence of other identical elements in the process, method, article or device including the element".

[0060] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A formula for softening and dispersing granules, characterized in that: The composition is composed of the following raw materials: 10-50g of Prunella Vulgaris, 10-15g of Curcuma Atractylodes, 10-30g of Fritillaria Thunbergii, 10-20g of Sophora flavescens, 10-20g of Trillium, 10-20g of Scrophularia ningpoensis, 4-13g of Pinellia ternata, 4-13g of Frankincense, 4-13g of Myrrh, 10-90g of White Peony Root, 10-14g of Bay Leaf, 2-12g of Ephedra sinica, 2-12g of Vinegar Tortoise Shell, 10-20g of Raw Dragon and Oyster Mud, 10-20g of Ginseng, 10-30g of Clematis, 8-13g of Hawthorn, 3-9g of Polygonum cuspidatum, 3-9g of Corydalis yanhusuo, 3-5g of Menthus fragrans, 3-9g of Burdock Root, 1-3g of Poria and 10-14g of Smilax glabra.

2. A formulation of softening and dispersing granules according to claim 1, characterized in that: It is composed of the following raw materials: 30g of Prunella Vulgaris, 12g of Curcuma, 20g of Fritillaria Thunbergii, 15g of Sophora flavescens, 15g of Trillium, 20g of Scrophularia ningpoensis, 9g of Pinellia ternata, 9g of Frankincense, 9g of Myrrh, 50g of White Peony Root, 12g of Bay Leaf, 7g of Ephedra sinica, 2g of Vinegar Tortoise Shell, 15g of Raw Dragon and Oyster Mud, 15g of Ginseng, 20g of Clematis, 11g of Hawthorn, 6g of Polygonum cuspidatum, 6g of Corydalis yanhusuo, 4g of Menthus, 6g of Burdock Root, 2g of Poria and 12g of Smilax glabra.

3. A method for preparing a hard-hardening and hard-dispersing granule formula, characterized in that: It consists of the following steps: Step 1, prepare the materials, weigh Prunella Vulgaris, Curcuma, Fritillaria Thunbergii, Sophora japonica, Psoralea corylifolia, Scrophularia ningpoensis, Pinellia ternata, frankincense, myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, Poria cocos and tongcao according to the proportion; Step 2: Remove weeds and clean the surface of the herb. Remove weeds and clean and dry the herb for later use. Select and dig up the roots of Curcuma zedoaria, remove the soil on the rhizomes, wash and dry them for later use; Wash the Fritillaria thunbergii, cut into sections, dry in the sun and set aside; Remove impurities from soapberry; soak uncut ones for a while, moisten thoroughly, cut into thick slices, wash and dry for later use; Remove impurities from Trillium, soak in water, pick up, soak thoroughly, slice, dry, and set aside; Pick out impurities from Scrophularia, remove the rhizome, wash and soak thoroughly, slice, and dry; Sift the ginger and pinellia tuber to remove the dust, wash and dry them for later use; Vinegar frankincense: take clean frankincense, add a certain amount of rice vinegar to the cleaned or cut medicine and stir-fry until the surface is shiny; Sift myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao to remove dust, wash and dry for later use; Step 3: Soaking the raw materials: adding all the dried grass, zedoaria, fritillaria thunbergii, soapberry, trillium, scrophularia, pinellia ternata and frankincense into a first soaking bucket, and adding clean water into the bucket to soak the materials; Step 4, concentration and extraction, the raw materials soaked in the first soaking barrel in step 3 are added to a crusher, the materials are chopped into particles, the mixed particle raw materials are put into a heating container, and clean water is added to soak, so that the clean water covers the top of the raw materials, the heating container heats the materials to boil, and after boiling, a low fire is turned on to continue boiling, the boiled materials are separated into solid and liquid, and the separated liquid is added to a centrifuge to centrifuge and filter the solid impurities to obtain a concentrated material; Step 5, add myrrh, white peony root, bay leaf, moxibustion ephedra, vinegar tortoise shell, raw dragon bone, ginseng, clematis, hawthorn, knotweed, corydalis, mint, burdock root, poria and tongcao as auxiliary materials into the grinder and grind and crush; Step 6: Add the mixed auxiliary materials ground and crushed in step 5 into the second soaking bucket, and soak them in clean water. After soaking, heat the storage container until it boils, stir the materials continuously during the boiling process, and then filter the liquid to obtain a filtrate; Step 7: Evenly mix the concentrated solution obtained in step 4 and the filtrate obtained in step 6, and then filter out impurities by centrifugation; Step 8, boiling and concentrating the mixed medicine again to form a thick paste; Step 9: The obtained thick paste is made into wet granules by a granulator, and then the granules are dried.

4. The method for preparing a hard-hardening and hard-dispersing granule formula according to claim 3, characterized in that: In step 3, the temperature of the clean water added to the first soaking bucket is 90°C.

5. The method for preparing a hard-hardening and hard-dispersing granule formula according to claim 3, characterized in that: In step 3, add clean water to the first soaking bucket and use a shovel to stir the raw materials along the edge of the bucket to the center of the bucket so that the water level is 20 cm above the surface of the material.

6. The method for preparing a hard-hardening and hard-dispersing granule formula according to claim 3, characterized in that: In step 3, the water temperature in the first soaking bucket is maintained at 75°C-80°C, and the soaking time is 8-12 hours.

7. The method for preparing a hard-hardening and hard-dispersing granule formula according to claim 3, characterized in that: In step 5, the auxiliary materials are crushed into 10-30 meshes.

8. The method for preparing a hard-hardening and hard-dispersing granule formula according to claim 3, characterized in that: In step eight, the relative density is concentrated to 1.2-1.

3.

9. The method for preparing a hard-hardening and hard-dispersing granule formula according to claim 3, characterized in that: After drying in step nine, sieve the particles with a 10-12 mesh sieve.