A multi-cell assembly installation auxiliary device for repairing endometrial injury
By designing a multi-cell assembly installation auxiliary equipment and using slider and reel mechanisms to cut and coil gel cell carriers, the problems of unstable assembly and irregular shape in the prior art are solved, and the accuracy and effectiveness of stable assembly and endometrial repair of multi-cell assembly are achieved.
Patent Information
- Application Number
- CN202411404918.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-10
- Publication Date
- 2025-07-01
- Estimated Expiration
- 2044-10-10
AI Technical Summary
The lack of dedicated auxiliary equipment during the installation of existing multi-cell assembly results in unstable assembly, irregular shape and structure, affecting the accuracy and effectiveness of endometrial repair.
A multi-cell assembly installation auxiliary equipment is designed, using slider and reel mechanisms to cut and wind up gel cell carriers to ensure the shape and structural stability of the cell carriers, and adjust the cutting specifications through an annular cutter and adjustment screws.
Through this device, the stable assembly and regular shape of multi-cell assembly is achieved, the accuracy and effectiveness of endometrial repair are improved, and the damage to cell activity is reduced.
Smart Images

Figure CN119286639B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of medical auxiliary devices, and more specifically, to a multi-cell assembly installation auxiliary device for repairing endometrial injury. Background Art
[0002] A multi-cell assembly is an organoid formed by assembling multiple cell types using a cell carrier, with a spatial organizational structure. They can be closer to real human tissues in terms of structure and function, and can be used as a research model to replace in vivo experiments for in vitro functional studies of human cells or tissues, helping researchers to understand tissue function more deeply. More importantly, the produced multi-cell assemblies can be applied to clinical tissue transplantation and injury repair treatments. The multi-cell assembly belongs to a three-dimensional, multi-level, tissue engineering constructed structure, and its preparation and assembly processes are complex. Therefore, it is necessary to design a multi-cell assembly installation auxiliary device that can simultaneously achieve automation of preparation and assembly and improve operation efficiency.
[0003] Before stacking and assembling the multi-cell assemblies, the cells need to be cultured in an existing incubator. After the cells are cultured in the incubator, gel is added and mixed, and after culturing for a period of time, it solidifies to form a cell carrier. When assembling the multi-cell assemblies, usually in a culture dish, the first layer of cells and gel are first mixed and cultured. After solidification, the second layer of cells and gel are mixed and then added to the first layer, and the same process is repeated to assemble the next layer of cell carrier. However, the surfaces of the cell carriers in different layers are irregular, the combination is unstable, and the assembled shape and size are not controlled. It is also possible to separately prepare different cell carriers, and then use a push plate or tweezers to pick up and transfer the cell carriers for stacking and installation. However, in the current above laboratory operations, only traditional laboratory cell culture equipment can be used, and there is no dedicated equipment that matches the assembly operation, which seriously affects the assembly process, and the assembly time is long, which may affect cell activity. During the process of stacking and assembling multiple layers of cell carriers, the traditional equipment for picking up or transferring cannot ensure the stability of the shape and structure of the assembled cell carriers and the flexibility of the operation. Especially when each layer of cell carrier is relatively thin, when using tweezers to pick up during the assembly process, the surface integrity of each layer of cell carrier is extremely easy to be damaged. If the positions of the cell carriers in each layer are inclined or shifted during the assembly and movement, it will cause the situation of misalignment of the cell carrier assembly, affecting the accuracy of endometrial assembly. Currently, there is no special equipment for assisting the installation of endometrial assemblies, and it can only be manually performed in the laboratory. The operation is cumbersome and rough. As a result, the shape and structure of the assembled cell carriers are irregular, affecting the subsequent in-vivo uterine cavity transplantation operation and the effectiveness of repairing endometrial injury. Summary of the Invention
[0004] The object of the present invention is to provide an installation auxiliary device for a multi - cell assembly for repairing endometrial injury, so as to solve the problems raised in the above - mentioned background technology:
[0005] In order to achieve the above object, the present invention provides the following technical solutions:
[0006] An installation auxiliary device for a multi - cell assembly for repairing endometrial injury, including an auxiliary device body. A workbench is fixedly installed on the top surface of the auxiliary device body. A bracket is fixedly installed on one end surface of the workbench. A chute is opened on the inner side surface of the bracket. A plurality of sliders matching with the chute are slidably connected inside the chute. A cutting knife is fixedly installed on the surface of any one of the sliders. A reel is rotatably connected to the surface of any one of the sliders. The reel is located on one side of the cutting knife. A film is fixedly coated on the surface of the reel. A first gear is coaxially and fixedly installed on the surface of the reel. The surface of the workbench is fixedly connected with culture boxes having the same number as the sliders. A culture dish matching with the culture box is slidably connected inside the culture box. A first toothed plate meshing with the first gear is fixedly installed on the inner side surface of the bracket. The number of the first toothed plates is the same as that of the culture boxes, and the first toothed plates and the culture boxes are in corresponding positions. A cutting table is fixedly installed on the surface of the workbench. The cutting table is located on one side of the culture box. A bottom film that can be laid is arranged on the surface of the cutting table. A gel cell carrier is arranged inside any one of the culture boxes. A second toothed plate corresponding to the cutting table is fixedly installed on the inner side surface of the bracket. The first gear is matched with the second toothed plate. A fixed seat capable of vertically moving up and down is arranged above the cutting table. An annular cutting knife is fixedly installed on the bottom surface of the fixed seat.
[0007] By adopting the above - mentioned technical solution, the movement of the slider drives the cutting knife and the reel to move. The movement of the cutting knife cuts the gel cell carrier inside the culture box. As the slider continues to move, at this time, the first gear rolls on the surface of the first toothed plate and drives the reel to rotate. A layer of the gel cell carrier cut by the cutting knife is wound on the surface of the film. A plurality of sliders move in the reverse direction in the chute. The gel cell carrier wound on the surface of the film moves towards the cutting table following the slider. The first gear rolls on the surface of the second toothed plate and drives the reel to rotate in the reverse direction, spreading the gel cell carrier wound on the surface of the film flat on the surface of the bottom film. The gel cell carriers wound on the surface of the film behind are stacked neatly one above the other. The plurality of reels and the plurality of culture boxes are in corresponding positions, so that the position of a layer of the gel cell carrier wound on the surface of the film is consistent, thereby preventing the misalignment of the assembly of the gel cell carriers. Using the reel to wind, compared with pushing plates or picking up with tweezers, it ensures the stability of the shape and structure of the assembled cell carrier. The shape and structure of the assembled gel cell carrier are regular, ensuring the effectiveness of subsequent human intrauterine transplantation operations and the repair of endometrial injury.
[0008] Preferably, a support frame is fixedly installed on the inner side surface of the bracket, an electric telescopic rod is fixedly installed on the bottom surface of the support frame, and the telescopic end of the electric telescopic rod is fixedly connected to the surface of the fixed seat.
[0009] Preferably, a transmission device for conveying the bottom film is arranged inside the cutting table, a servo motor for driving the transmission device is fixedly installed on the surface of the cutting table, and multiple layers of assembled cell carriers are stacked and placed on the surface of the bottom film.
[0010] Preferably, a lead screw is rotatably connected inside the sliding groove, the slider is slidably connected to the sliding groove through the lead screw, a first motor is fixedly installed on the surface of one end of the bracket, the output end of the first motor is fixedly connected to the lead screw, a connecting frame is fixedly installed on the inner side surface of one end of the bracket, a controller is fixedly installed on the surface of the connecting frame, and the first motor is electrically connected to the controller through a wire.
[0011] Preferably, the electric telescopic rod is electrically connected to the controller through a wire, and the servo motor is electrically connected to the controller through a wire.
[0012] Preferably, the annular cutting knife includes two corresponding fixed knife plates, a first movable ring knife and a second movable ring knife. An activity groove is formed inside the two fixed knife plates. The first movable ring knife and the second movable ring knife are both slidably connected to the fixed knife plates through the activity groove. A partition plate is fixedly installed on the inner wall of the activity groove. First springs are arranged on both sides of the partition plate. The first movable ring knife and the second movable ring knife are both elastically connected to the partition plate through the first springs. A fixed plate is fixedly installed between the two fixed knife plates. Corresponding end surfaces of the fixed plate are fixedly connected with threaded rods. One ends of the two threaded rods respectively penetrate through the first movable ring knife and the second movable ring knife, and adjusting screws are arranged on the surfaces of the two threaded rods.
[0013] By adopting the above technical solution, by rotating the adjusting screw, the first movable ring knife and the second movable ring knife move towards the inside of the fixed knife plate to squeeze the first spring. During the process of adjusting the size of the annular cutting knife, the scale is observed in real time, so that the annular cutting knife is adjusted to a cutting specification suitable for the size of the endometrial injury, which increases the function of the auxiliary device body and makes the auxiliary device body multifunctional.
[0014] Preferably, a scale for observing the positions of the first movable ring knife and the second movable ring knife is arranged on the surface of one of the fixed knife plates, and the scale is fixedly connected to the surface of the fixed knife plate.
[0015] By adopting the above technical solution, the setting of the scale can observe the movement positions of the first movable ring knife and the second movable ring knife in real time.
[0016] Preferably, a vertical plate is fixedly connected inside the auxiliary device body. A moving groove is formed on the surface of the vertical plate. A movable frame matching the moving groove is slidably connected inside the moving groove. One end of the movable frame is fixedly connected with a moving plate. The top surface of the moving plate is fixedly installed with slope blocks having the same number as the incubators. The bottom surface of the incubator is slidably connected with a guide rod. One end of the guide rod is fixedly connected with the bottom surface of the culture dish. The other end of the guide rod is fixedly connected with a ball head contacting the slope block. A second spring is elastically connected between the culture dish and the incubator.
[0017] By adopting the above technical solution, the reciprocating movement of the moving plate drives multiple slope blocks to move, thereby causing the slope blocks to squeeze the ball head to different degrees. The guide rod follows the movement of the ball head to drive the culture dish to move and stretch the second spring. The movement of the culture dish pushes the gel cell carrier inside the incubator out. The different degrees of squeezing of the ball head by the slope blocks enable the height of the gel cell carrier leaking out of the incubator to be adjusted, thereby realizing that the cutting knife can cut gel cell carriers with different thicknesses.
[0018] Preferably, a third toothed plate is fixedly connected to the bottom surface of the moving plate. A second gear meshing with the third toothed plate is rotatably connected to the bottom surface of the third toothed plate. A second motor is fixedly installed on the surface of the vertical plate. The output end of the second motor is fixedly connected with the second gear.
[0019] Preferably, one end of the second spring is fixedly connected with the bottom surface of the culture dish, and the other end of the second spring is fixedly connected with the inner bottom surface of the incubator.
[0020] Compared with the prior art, the beneficial effects of the present invention are:
[0021] 1) When the auxiliary device for installing the multi - cell assembly for repairing endometrial injury operates, the movement of the slider drives the cutting knife and the reel to move. The movement of the cutting knife cuts the gel cell carrier inside the incubator. As the slider continues to move, at this time, the first gear rolls on the surface of the first toothed plate to drive the reel to rotate. The layer of gel cell carrier cut by the cutting knife is wound on the surface of the film. Multiple sliders move in the reverse direction in the chute. The gel cell carrier wound on the surface of the film follows the slider and moves towards the cutting table. The first gear rolls on the surface of the second toothed plate to drive the reel to rotate in the reverse direction, and the gel cell carrier wound on the surface of the film is spread flat on the surface of the bottom film. The subsequent gel cell carriers wound on the surface of the film are stacked neatly one above the other. The multiple reels correspond to the positions of the multiple incubators, so that the position of the layer of gel cell carrier wound on the surface of the film is consistent, thereby preventing the misalignment of the assembly of the gel cell carrier. Using the reel to wind, compared with the push plate or the forceps to pick up, it ensures the stability of the shape and structure of the assembled cell carrier. The shape and structure of the assembled gel cell carrier are regular, ensuring the effectiveness of the subsequent human intrauterine transplantation operation and the repair of endometrial injury.
[0022] 2) When the multi - cell assembly installation auxiliary device for repairing endometrial injury is in operation, by rotating the adjusting screw, the first movable ring cutter and the second movable ring cutter move towards the inside of the fixed cutter plate to squeeze the first spring. During the process of adjusting the size of the circular cutter, the scale is observed in real - time, so that the circular cutter is adjusted to a cutting specification suitable for the size of the endometrial injury, which increases the function of the auxiliary device body and makes the auxiliary device body more versatile.
[0023] 3) When the multi - cell assembly installation auxiliary device for repairing endometrial injury is in operation, the moving plate reciprocates to drive multiple ramp blocks to move. Then, the ramp blocks squeeze the ball head to different degrees. The guide rod follows the movement of the ball head to drive the culture dish to move and stretch the second spring. The movement of the culture dish pushes the gel cell carrier inside the culture box out. The different degrees of extrusion of the ramp blocks on the ball head enable the height of the gel cell carrier leaking out of the culture box to be adjustable, so that the cutting knife can cut gel cell carriers with different thicknesses. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 is the overall structural schematic diagram of the present invention;
[0025] Figure 2 is the surface structural schematic diagram of the workbench of the present invention;
[0026] Figure 3 is the structural schematic diagram of the position of the chute and the slider of the present invention;
[0027] Figure 4 is the structural schematic diagram of the position of the moving plate and the ramp block of the present invention;
[0028] Figure 5 is the structural schematic diagram of the position of the culture box and the first toothed plate of the present invention;
[0029] Figure 6 is the structural schematic diagram of the cutting table of the present invention;
[0030] Figure 7 is the structural schematic diagram of the circular cutter of the present invention;
[0031] Figure 8 is the structural schematic diagram of the installation position of the fixed plate and the threaded rod of the present invention;
[0032] Figure 9 is the structural schematic diagram of the position of the movable frame and the moving plate of the present invention;
[0033] Figure 10 is the internal structural schematic diagram of the culture box of the present invention.
[0034] Description of reference numerals in the figure: 1. Auxiliary equipment body; 2. Workbench; 3. Bracket; 4. Slide groove; 5. Slide block; 6. Cutting knife; 7. Reel; 8. Film; 9. First gear; 10. Incubator; 11. First toothed plate; 12. Cutting table; 13. Transmission equipment; 14. Bottom film; 15. Gel cell carrier; 16. Support frame; 17. Electric telescopic rod; 18. Fixed seat; 19. Ring cutter; 20. Second toothed plate; 21. Lead screw; 22. First motor; 23. Connecting frame; 24. Controller; 25. Assembled cell carrier; 26. Servo motor; 27. First movable ring cutter; 28. Second movable ring cutter; 29. Movable groove; 30. Partition board; 31. First spring; 32. Scale; 33. Fixed plate; 34. Threaded rod; 35. Adjusting screw; 36. Vertical plate; 37. Movable frame; 38. Moving plate; 39. Second motor; 40. Moving groove; 41. Third toothed plate; 42. Ramp block; 43. Second gear; 44. Petri dish; 45. Guide rod; 46. Ball head; 47. Second spring; 48. Fixed knife plate. Detailed implementation manner
[0035] Example 1
[0036] Please refer to Figures 1 to 10, A multi - cell assembly installation auxiliary device for repairing endometrial injury, including an auxiliary device body 1. The auxiliary device body 1 can automatically produce multi - cell assemblies. A workbench 2 is fixedly installed on the top surface of the auxiliary device body 1. A bracket 3 is fixedly installed on one end surface of the workbench 2. A chute 4 is provided on the inner side surface of the bracket 3. A plurality of sliders 5 matching with it are slidably connected inside the chute 4. A cutting knife 6 is fixedly installed on the surface of any one of the sliders 5. A reel 7 is rotatably connected to the surface of any one of the sliders 5. The reel 7 is located on one side of the cutting knife 6. A film 8 is fixedly coated on the surface of the reel 7. According to the height of the gel cell carrier 15, multiple layers of the film 8 can be wound around the surface of the reel 7 so that the film 8 and the gel cell carrier 15 are at the same height. A first gear 9 is coaxially fixedly installed on the surface of the reel 7. The first gear 9 meshes with a first toothed plate 11, and the first gear 9 rotates in units of turns on the surface of the first toothed plate 11. The surface of the workbench 2 is fixedly connected with incubators 10 having the same number as the sliders 5. A culture dish 44 matching with it is slidably connected inside the incubator 10. The culture dish 44 and the inner wall of the incubator 10 form a culture space. The incubator 10 is a conventional small - scale temperature - controlled incubator 10 in the prior art. Cells are added into the culture space formed by the culture dish 44 and the inner wall of the incubator 10. The incubator 10 works to culture the cells for 30 to 60 minutes. After the cell culture is completed, gel (the viscosity of the gel can be adjusted) is added. After the cell mass is stable, the culture dish 44 rises to push out the formed gel cells, and then the next step of cutting, stacking and assembling is carried out. A first toothed plate 11 meshing with the first gear 9 is fixedly installed on the inner side surface of the bracket 3. The number of the first toothed plates 11 is the same as that of the incubators 10, and the first toothed plates 11 and the incubators 10 are in corresponding positions. A cutting table 12 is fixedly installed on the surface of the workbench 2. The cutting table 12 is located on one side of the incubator 10. A bottom film 14 that can be laid is provided on the surface of the cutting table 12. A gel cell carrier 15 is provided inside any one of the incubators 10. The gel cell carrier 15 is a gel cell carrier 15 with gel solidified in the prior art. A second toothed plate 20 corresponding to the position of the cutting table 12 is fixedly installed on the inner side surface of the bracket 3. The first gear 9 matches with the second toothed plate 20, and the first gear 9 rotates in units of turns on the surface of the second toothed plate 20. A fixed seat 18 that can move vertically up and down is provided above the cutting table 12. An annular cutting knife 19 is fixedly installed on the bottom surface of the fixed seat 18. By the movement of the slider 5, the cutting knife 6 and the reel 7 are driven to move. The cutting knife 6 moves to cut the gel cell carrier 15 inside the incubator 10. As the slider 5 continues to move, at this time, the first gear 9 rolls on the surface of the first toothed plate 11 to drive the reel 7 to rotate, and a layer of the gel cell carrier 15 cut by the cutting knife 6 is wound on the surface of the film 8. The multiple sliders 5 move in the reverse direction in the chute 4, and the gel cell carrier 15 wound on the surface of the film 8 moves towards the cutting table 12 following the slider 5. The first gear 9 rolls on the surface of the second toothed plate 20 to drive the reel 7 to rotate in the reverse direction.The gel cell carrier 15 wound on the surface of the film 8 is laid flat on the surface of the bottom film 14, and the gel cell carriers 15 wound on the surface of the film 8 later are stacked neatly one above the other. The multiple reels 7 correspond to the positions of the multiple incubators 10, so that the positions of one layer of the gel cell carrier 15 wound on the surface of the film 8 are the same, thereby preventing the gel cell carrier 15 from being assembled out of position. Using the reel 7 to wind, compared with using a push plate or tweezers to pick up, it ensures the stability of the shape and structure of the assembled cell carrier 25. The assembled gel cell carrier 15 has a regular shape and structure, ensuring the effectiveness of subsequent intrauterine transplantation operations in the human body and the repair of endometrial injuries.
[0037] A support frame 16 is fixedly installed on the inner side surface of the bracket 3. A power telescopic rod 17 is fixedly installed on the bottom surface of the support frame 16. The power telescopic rod 17 is a conventional electric control push rod in the prior art. The telescopic end of the power telescopic rod 17 is fixedly connected to the surface of the fixed seat 18. The power telescopic rod 17 provides power for the movement of the circular cutter 19.
[0038] A transmission device 13 for conveying the bottom film 14 is arranged inside the cutting table 12. The transmission device 13 is a conventional device for conveying the bottom film 14 in the prior art. A servo motor 26 for driving the transmission device 13 is fixedly installed on the surface of the cutting table 12. Multiple layers of assembled cell carriers 25 are stacked on the surface of the bottom film 14. The servo motor 26 is a conventional servo rotating device in the prior art.
[0039] A lead screw 21 is rotatably connected inside the chute 4. The slider 5 is slidably connected to the chute 4 through the lead screw 21. A first motor 22 is fixedly installed on the surface of one end of the bracket 3. The first motor 22 is a conventional forward and reverse motor in the prior art. The output end of the first motor 22 is fixedly connected to the lead screw 21. A connecting frame 23 is fixedly installed on the inner side surface of one end of the bracket 3. A controller 24 is fixedly installed on the surface of the connecting frame 23. The first motor 22 is electrically connected to the controller 24 through a wire. The controller 24 is a conventional programmable controller 24 in the prior art.
[0040] The power telescopic rod 17 is electrically connected to the controller 24 through a wire. The servo motor 26 is electrically connected to the controller 24 through a wire.
[0041] Steps of using the present invention: When the multi-cell assembly installation auxiliary device for repairing endometrial injury is in use, in the initial position, multiple incubators 10 and multiple sliders 5 are arranged at staggered intervals. When stacking multi-layer cell carriers, by operating the controller 24, at this time, the first motor 22 rotates forward to drive the lead screw 21 to rotate. Multiple equally spaced sliders 5 move simultaneously inside the chute 4. The movement of the slider 5 drives the cutting knife 6 and the reel 7 to move. The movement of the cutting knife 6 cuts the gel cell carrier 15 inside the incubator 10. The surface of the reel 7 is at the same height as the gel cell carrier 15. When the first gear 9 moves to mesh with the first toothed plate 11, as the slider 5 continues to move, at this time, the first gear 9 rolls on the surface of the first toothed plate 11 to drive the reel 7 to rotate. Since the surface of the reel 7 is fixedly coated with a film 8, at this time, a layer of the gel cell carrier 15 cut by the cutting knife 6 is wound on the surface of the film 8. When the reel 7 finishes winding a layer of the gel cell carrier 15, at this time, the first gear 9 disengages from the first toothed plate 11. Multiple reels 7 finish winding multiple layers of the gel cell carrier 15. The first motor 22 rotates in reverse to drive multiple sliders 5 to move in the reverse direction inside the chute 4. At this time, the gel cell carrier 15 wound on the reel 7 moves with the slider 5. At this time, the gel cell carrier 15 wound on the surface of the film 8 moves towards the cutting table 12 with the slider 5. During the movement of the gel cell carrier 15 wound on the surface of the film 8, it will not contact the surface of the uncut gel cell carrier 15 inside the incubator 10. When the first gear 9 moves to contact the second toothed plate 20, as the first gear 9 rolls on the surface of the second toothed plate 20 to drive the reel 7 to rotate in the reverse direction, the servo motor 26 is started in advance, so that the transmission device 13 works to lay the bottom film 14 on the surface of the cutting table 12. The reel 7 rotates in the reverse direction to spread the gel cell carrier 15 wound on the surface of the film 8 flat on the surface of the bottom film 14. The subsequent gel cell carriers 15 wound on the surface of the film 8 are stacked neatly one above the other. After the stacking is completed, the electric telescopic rod 17 extends to drive the annular cutting knife 19 to move downward to cut the neatly stacked multi-layer assembled cell carriers 25. After the cutting is completed, the electric telescopic rod 17 retracts to drive the annular cutting knife 19 to reset. At this time, the cut assembled cell carriers 25 are taken off from the surface of the cutting table 12. By operating the controller 24 again, multiple sliders 5 move back to the initial position, adjust the height of the gel cell carrier 15, and repeat the above steps again. In this scheme, the movement of the slider 5 drives the cutting knife 6 and the reel 7 to move. The movement of the cutting knife 6 cuts the gel cell carrier 15 inside the incubator 10. As the slider 5 continues to move, at this time, the first gear 9 rolls on the surface of the first toothed plate 11 to drive the reel 7 to rotate. A layer of the gel cell carrier 15 cut by the cutting knife 6 is wound on the surface of the film 8. Multiple sliders 5 move in the reverse direction inside the chute 4. The gel cell carrier 15 wound on the surface of the film 8 moves towards the cutting table 12 with the slider 5. The first gear 9 rolls on the surface of the second toothed plate 20 to drive the reel 7 to rotate in the reverse direction, and spreads the gel cell carrier 15 wound on the surface of the film 8 flat on the surface of the bottom film 14.The gel cell carriers 15 wound on the surface of the film 8 at the back are stacked neatly one above the other in sequence. A plurality of reels 7 correspond to a plurality of incubators 10 in position, so that the positions of one layer of gel cell carriers 15 wound on the surface of the film 8 are the same, thereby preventing the gel cell carriers 15 from being assembled out of position. Using the reel 7 to wind, compared with picking up by a push plate or tweezers, it ensures the stability of the shape and structure of the assembled cell carrier 25. The assembled gel cell carriers 15 have regular shapes and structures, ensuring the effectiveness of subsequent intrauterine transplantation operations on the human body and the repair of endometrial injuries.
[0042] Example 2
[0043] When repairing endometrial injuries, it is necessary to select multi-layer assembled cell carriers 25 of appropriate sizes according to the size of the injuries. For cutting the assembled cell carriers 25, it is necessary to cut them into assembled cell carriers 25 of different sizes in advance. The problem is solved through the following solutions.
[0044] Please refer to Figures 1 to 10 , the difference based on Example 1 is that the annular cutter 19 includes two corresponding fixed knife plates 48, a first movable ring knife 27 and a second movable ring knife 28. Activity grooves 29 are formed inside the two fixed knife plates 48. The first movable ring knife 27 and the second movable ring knife 28 are both slidably connected to the fixed knife plates 48 through the activity grooves 29. Partition plates 30 are fixedly installed on the inner walls of the activity grooves 29. First springs 31 are arranged on both sides of the partition plates 30. The first movable ring knife 27 and the second movable ring knife 28 are both elastically connected to the partition plates 30 through the first springs 31. A fixing plate 33 is fixedly installed between the two fixed knife plates 48. Corresponding end surfaces of the fixing plate 33 are fixedly connected with threaded rods 34. One ends of the two threaded rods 34 respectively penetrate through the first movable ring knife 27 and the second movable ring knife 28. Adjusting screws 35 are arranged on the surfaces of the two threaded rods 34. By rotating the adjusting screws 35, the first movable ring knife 27 and the second movable ring knife 28 move towards the inside of the fixed knife plates 48 to squeeze the first springs 31. During the process of adjusting the size of the annular cutter 19, the scale 32 is observed in real time, so that the annular cutter 19 is adjusted to a cutting specification suitable for the size of the endometrial injury, increasing the functions of the auxiliary device body 1 and making the auxiliary device body 1 multifunctional.
[0045] A scale 32 for observing the positions of the first movable ring knife 27 and the second movable ring knife 28 is arranged on the surface of one of the fixed knife plates 48. The scale 32 is fixedly connected to the surface of the fixed knife plate 48. The setting of the scale 32 can observe the movement positions of the first movable ring knife 27 and the second movable ring knife 28 in real time.
[0046] Usage steps of the present invention: When this multi-cell assembly installation auxiliary device for repairing endometrial injury is in use, before the annular cutter 19 cuts the neatly stacked assembled cell carriers 25, according to the size of the endometrial injury, the overall size of the annular cutter 19 is adjusted. During the adjustment, by rotating the adjustment screw 35, the first movable ring cutter 27 and the second movable ring cutter 28 move towards the inside of the fixed cutter plate 48 to squeeze the first spring 31. During the process of adjusting the size of the annular cutter 19, the scale 32 is observed in real time, so that the annular cutter 19 is adjusted to a cutting specification suitable for the size of the endometrial injury. In this solution, by rotating the adjustment screw 35, the first movable ring cutter 27 and the second movable ring cutter 28 move towards the inside of the fixed cutter plate 48 to squeeze the first spring 31. During the process of adjusting the size of the annular cutter 19, the scale 32 is observed in real time, so that the annular cutter 19 is adjusted to a cutting specification suitable for the size of the endometrial injury, which increases the functions of the auxiliary device body 1 and makes the auxiliary device body 1 more versatile.
[0047] Embodiment 3
[0048] After the assembled cell carriers 25 are assembled with different thicknesses, it is necessary to cut the gel cell carriers 15 with different thicknesses inside the incubator 10. The problem is solved through the following solution.
[0049] Please refer to Figures 1 to 10 , which is different from the basis of Embodiment 1 in that a vertical plate 36 is fixedly connected inside the auxiliary device body 1. A moving groove 40 is formed on the surface of the vertical plate 36. A movable frame 37 matching the moving groove 40 is slidably connected inside the moving groove 40. One end of the movable frame 37 is fixedly connected with a moving plate 38. The top surface of the moving plate 38 is fixedly installed with slope blocks 42 having the same number as the incubators 10. The bottom surface of the incubator 10 is slidably connected with a guide rod 45. One end of the guide rod 45 is fixedly connected with the bottom surface of the culture dish 44. The other end of the guide rod 45 is fixedly connected with a ball head 46 in contact with the slope block 42. A second spring 47 is elastically connected between the culture dish 44 and the incubator 10. By reciprocating the movement of the moving plate 38 to drive the movement of a plurality of slope blocks 42, the slope blocks 42 squeeze the ball head 46 to different degrees. The guide rod 45 drives the movement of the culture dish 44 to stretch the second spring 47 following the movement of the ball head 46. The movement of the culture dish 44 pushes out the gel cell carrier 15 inside the incubator 10. The different degrees of squeezing of the ball head 46 by the slope blocks 42 enable the height of the gel cell carrier 15 leaking out of the incubator 10 to be adjustable, so as to realize that the cutting knife 6 can cut the gel cell carriers 15 with different thicknesses.
[0050] The bottom surface of the moving plate 38 is fixedly connected with a third toothed plate 41. The bottom surface of the third toothed plate 41 is rotatably connected with a second gear 43 meshing with it. The surface of the vertical plate 36 is fixedly installed with a second motor 39. The output end of the second motor 39 is fixedly connected with the second gear 43. The second motor 39 is a conventional forward and reverse motor in the prior art.
[0051] One end of the second spring 47 is fixedly connected with the bottom surface of the culture dish 44, and the other end of the second spring 47 is fixedly connected with the inner bottom surface of the incubator 10. The second spring 47 is used for the reset of the culture dish 44.
[0052] Usage steps of the present invention: When the multi-cell assembly installation auxiliary device for repairing endometrial injury is in use, operate the controller 24. The second motor 39 rotates forward and backward to drive the second gear 43 to rotate, so that the moving plate 38 reciprocates to drive a plurality of ramp blocks 42 to move. Furthermore, the ramp blocks 42 squeeze the ball head 46 to different degrees. The guide rod 45 follows the movement of the ball head 46 to drive the culture dish 44 to move and stretch the second spring 47. The movement of the culture dish 44 pushes out the gel cell carrier 15 inside the incubator 10. This solution drives a plurality of ramp blocks 42 to move through the reciprocating movement of the moving plate 38. Furthermore, the ramp blocks 42 squeeze the ball head 46 to different degrees. The guide rod 45 follows the movement of the ball head 46 to drive the culture dish 44 to move and stretch the second spring 47. The movement of the culture dish 44 pushes out the gel cell carrier 15 inside the incubator 10. The ramp blocks 42 squeeze the ball head 46 to different degrees, so that the height of the gel cell carrier 15 leaking out of the incubator 10 can be adjusted. Furthermore, the cutting knife 6 can cut the gel cell carrier 15 with different thicknesses.
[0053] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art of this industry should understand that the present invention is not limited by the above embodiments. The above embodiments and the descriptions in the specification are only preferred examples of the present invention and are not used to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection of the present invention is defined by the appended claims and their equivalents.
Claims
1. A multi-cell assembly installation auxiliary device for repairing endometrial damage, comprising an auxiliary device body (1), characterized in that: A workbench (2) is fixedly mounted on the top surface of the auxiliary equipment body (1), a bracket (3) is fixedly mounted on one end surface of the workbench (2), a slide groove (4) is provided on the inner side surface of the bracket (3), a plurality of sliders (5) matching therewith are slidably connected inside the slide groove (4), a cutting knife (6) is fixedly mounted on the surface of any one of the sliders (5), a reel (7) is rotatably connected to the surface of any one of the sliders (5), the reel (7) is located on one side of the cutting knife (6), a film (8) is fixedly coated on the surface of the reel (7), a first gear (9) is coaxially fixedly mounted on the surface of the reel (7), the surface of the workbench (2) is fixedly connected with the same number of incubators (10) as the sliders (5), the interior of the incubators (10) is slidably connected with culture dishes (44) matching therewith, the inner side of the bracket (3) A first tooth plate (11) meshing with a first gear (9) is fixedly installed on the surface of the workbench (2), the number of the first tooth plates (11) is the same as that of the incubator (10), and the positions of the first tooth plates (11) and the incubator (10) correspond to each other; a cutting table (12) is fixedly installed on the surface of the workbench (2), the cutting table (12) is located on one side of the incubator (10), the surface of the cutting table (12) is provided with a paved bottom film (14), any one of the incubators (10) is provided with a gel cell carrier (15), a second tooth plate (20) corresponding to the position of the cutting table (12) is fixedly installed on the inner side surface of the bracket (3), the first gear (9) matches the second tooth plate (20), a fixing seat (18) capable of vertical up and down movement is provided above the cutting table (12), and a ring-shaped cutter (19) is fixedly installed on the bottom surface of the fixing seat (18); A support frame (16) is fixedly mounted on the inner side surface of the bracket (3), an electric telescopic rod (17) is fixedly mounted on the bottom surface of the support frame (16), and the telescopic end of the electric telescopic rod (17) is fixedly connected to the surface of the fixing seat (18); A transmission device (13) for transmitting a base film (14) is arranged inside the cutting table (12), a servo motor (26) for driving the transmission device (13) is fixedly mounted on the surface of the cutting table (12), and a plurality of layers of assembled cell carriers (25) are stacked and placed on the surface of the base film (14); The slide groove (4) is internally rotatably connected with a screw rod (21), the slider (5) is slidably connected to the slide groove (4) through the screw rod (21), a first motor (22) is fixedly mounted on the surface of one end of the bracket (3), the output end of the first motor (22) is fixedly connected to the screw rod (21), a connecting frame (23) is fixedly mounted on the inner side surface of one end of the bracket (3), a controller (24) is fixedly mounted on the surface of the connecting frame (23), and the first motor (22) is electrically connected to the controller (24) through a wire; The electric telescopic rod (17) is electrically connected to the controller (24) via a wire, and the servo motor (26) is electrically connected to the controller (24) via a wire.
2. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 1, characterized in that: The annular cutter (19) comprises two corresponding fixed blade plates (48), a first movable ring blade (27) and a second movable ring blade (28). The two fixed blade plates (48) are provided with movable grooves (29) inside. The first movable ring blade (27) and the second movable ring blade (28) are both slidably connected to the fixed blade plate (48) through the movable grooves (29). A partition plate (30) is fixedly installed on the inner wall of the movable groove (29). Both sides of the partition plate (30) are provided with first springs (31). The first movable ring knife (27) and the second movable ring knife (28) are elastically connected to the partition (30) via a first spring (31); a fixed plate (33) is fixedly installed between the two fixed knife plates (48); the corresponding end surfaces of the fixed plate (33) are fixedly connected with threaded rods (34); one end of the two threaded rods (34) respectively penetrates the first movable ring knife (27) and the second movable ring knife (28); and the surfaces of the two threaded rods (34) are provided with adjusting screws (35).
3. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 2, characterized in that: A scale (32) for observing the positions of the first movable ring knife (27) and the second movable ring knife (28) is provided on the surface of one of the fixed knife plates (48), and the scale (32) is fixedly connected to the surface of the fixed knife plate (48).
4. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 1, characterized in that: The auxiliary equipment body (1) is fixedly connected with a vertical plate (36) inside, a movable groove (40) is provided on the surface of the vertical plate (36), a movable frame (37) matching with the vertical plate (36) is slidably connected inside the movable groove (40), a movable plate (38) is fixedly connected to one end of the movable frame (37), a slope block (42) the same number as the incubator (10) is fixedly mounted on the top surface of the movable plate (38), a guide rod (45) is slidably connected to the bottom surface of the incubator (10), one end of the guide rod (45) is fixedly connected to the bottom surface of the incubator (44), the other end of the guide rod (45) is fixedly connected to a ball head (46) in contact with the slope block (42), and a second spring (47) is elastically connected between the incubator (44) and the incubator (10).
5. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 4, characterized in that: The bottom surface of the movable plate (38) is fixedly connected to a third tooth plate (41), and the bottom surface of the third tooth plate (41) is rotatably connected to a second gear (43) meshing therewith. A second motor (39) is fixedly mounted on the surface of the vertical plate (36), and an output end of the second motor (39) is fixedly connected to the second gear (43).
6. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 4, characterized in that: One end of the second spring (47) is fixedly connected to the bottom surface of the culture dish (44), and the other end of the second spring (47) is fixedly connected to the inner bottom surface of the culture box (10).
Citation Information
Patent Citations
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