Insecticidal composition and application thereof

Abstract

The invention belongs to the technical field of pesticide compounding, and particularly relates to an insecticidal composition, the effective components of the insecticidal composition comprise an active component A and an active component B, the active component A is a compound represented by a formula (I), the active component B is an aryl isoxazoline insecticide, and the mass ratio of the active component A to the active component B is 1: 30-40: 1. The compound insecticide disclosed by the invention has an obvious synergistic effect, the dosage of the insecticide is reduced, the production cost and the environmental risk are reduced, the generation of drug resistance of pests is delayed, and the compound insecticide can be used for comprehensive treatment of resistant pests and used for preventing and treating hemiptera, lepidoptera and coleoptera pests.

Description

Technical Field

[0001] The invention belongs to the technical field of pesticides and insecticides, and in particular relates to an insecticide composition and its application in preventing and controlling lepidopteran pests. Background Art

[0002] Aryl isoxazolines, such as fluoxetine and isoxazoline, are allosteric modulators of γ-aminobutyric acid (GABA)-gated chloride channels. They block activated γ-aminobutyric acid chloride channels by allosteric blocking, causing pests to become overexcited and spasmodic, ultimately leading to death. They have a unique mechanism of action, have no cross-resistance with other insecticides, and exhibit high broad-spectrum activity against various lepidoptera, thysanoptera, and diptera pests.

[0003] After the inventors' compounding research, the compound represented by formula (I) was rationally compounded with aromatic isoxazoline insecticides, such as fluazifop and cyprodinil, and surprisingly found that the insecticidal composition had a synergistic effect under a certain mass ratio, and there are no related reports on the compounding of the compound represented by formula (I) with fluazifop and cyprodinil. Summary of the invention

[0004] The purpose of the present invention is to provide an insecticide composition which has synergistic effect, reduces drug resistance, has low use cost and good prevention effect.

[0005] To achieve the above object, the technical solution adopted by the present invention is: an insecticide composition, wherein the active ingredients of the insecticide composition include active ingredient A and active ingredient B, and active ingredient A is a compound of formula (I), and the structural formula is as follows:

[0006] The active ingredient B is an arylisoxazoline insecticide.

[0007] Furthermore, the aromatic isoxazoline insecticide is selected from any one of oxazolidinone and cyprodinil;

[0008] Furthermore, the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 40:1;

[0009] Furthermore, the mass ratio of the active ingredient A to the active ingredient B is 1:28 to 28:1 or any value between the above values;

[0010] Furthermore, the mass ratio of the compound of formula (I) to oxazolidinone is 1:30 to 22:1;

[0011] Furthermore, the mass ratio of the compound of formula (I) to oxazolidinone is 1:18 to 22:1;

[0012] Furthermore, the mass ratio of the compound of formula (I) to oxazolidinone is 1:30, 1:18, 1:9, 2:5, 3:2, 6:1, 14:1, 22:1;

[0013] Furthermore, the mass ratio of the compound of formula (I) to oxazolidinone is 1:18, 1:9, 2:5, 3:2, 6:1, 14:1, 22:1;

[0014] Furthermore, the mass ratio of the compound of formula (I) to cyprodinil is 1:28 to 40:1;

[0015] Furthermore, the mass ratio of the compound of formula (I) to cyfluthrin is 1:28 to 28:1;

[0016] Furthermore, the mass ratio of the compound of formula (I) to cyfluthrin is 1:28, 1:14, 1:7, 4:1, 8:1, 12:1, 28:1, 40:1;

[0017] Furthermore, the mass ratio of the compound of formula (I) to cyfluthrin is 1:28, 1:14, 1:7, 4:1, 8:1, 12:1, 28:1;

[0018] Furthermore, based on the total weight of the insecticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 0.5 to 90 wt%;

[0019] Furthermore, based on the total weight of the insecticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 1 to 80 wt%;

[0020] The insecticide composition of the present invention can be prepared by a processing method known to those skilled in the art, that is, after mixing the active ingredient with a liquid solvent or a solid carrier, one or more of a surfactant such as a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a stabilizer, a penetrant and a carrier are added;

[0021] Further, the wetting agent is selected from a mixture of one or more of sodium dodecyl sulfate, sodium dodecylbenzene sulfonate, lakai powder BX, wetting and penetrating agent F, sapodilla powder, silkworm feces or soapberry powder;

[0022] Further, the dispersant is selected from a mixture of one or more of polycarboxylates, lignin sulfonates, alkylphenol polyoxyethylene ether formaldehyde condensate sulfates, alkylbenzene sulfonate calcium, naphthalenesulfonic acid formaldehyde condensate sodium salts, alkylphenol polyoxyethylene ether phosphates, fatty amine polyoxyethylene ethers, fatty acid polyoxyethylene ethers or glycerol fatty acid ester polyoxyethylene ethers;

[0023] Furthermore, the emulsifier is selected from Nongru 500# (calcium alkylbenzene sulfonate), OP series phosphate ester (nonylphenol polyoxyethylene ether phosphate), 600# phosphate ester (phenylphenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether ammonium sulfate, alkyl biphenyl ether disulfonic acid magnesium salt, triethanolamine salt, Nongru 400# (benzyl dimethylphenol polyoxyethyl ether), Nongru 700# (alkylphenol formaldehyde resin polyoxyethyl ether), Ningru 36# (phenylethylphenol formaldehyde resin polyoxyethylene ether), A mixture of one or more of the following: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 51, 52, 53, 54, 55, 56, 57, 58, 59, 61, 62, 63, 64, 65, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 101, 114, 115, 126, 130, 131, 132, 133, 134, 135, 136, 137

[0024] Furthermore, the thickener is selected from a mixture of one or more of xanthan gum, polyvinyl alcohol, bentonite, carboxymethyl cellulose or magnesium aluminum silicate;

[0025] Further, the disintegrant is selected from a mixture of one or more of bentonite, urea, ammonium sulfate, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate;

[0026] Further, the antifreeze agent is selected from a mixture of one or more of ethylene glycol, propylene glycol, glycerol or urea;

[0027] Furthermore, the defoaming agent is selected from silicone oil, silicone compounds, C 10 ~C 20 Saturated fatty acid compounds or C8~C 10 A mixture of one or more fatty alcohol compounds;

[0028] Further, the solvent is selected from a mixture of one or more of N,N-dimethylformamide, cyclohexanone, toluene, xylene, dimethyl sulfoxide, methanol, ethanol, trimethylcyclohexanone, N-octylpyrrolidone, ethanolamine, triethanolamine, isopropylamine, N-methylpyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, ethanolamine, isopropylamine, ethyl acetate or acetonitrile;

[0029] Further, the stabilizer is selected from a mixture of one or more of epoxy soybean oil, epichlorohydrin, BHT, ethyl acetate, and triphenyl phosphate;

[0030] Further, the penetrant is selected from a mixture of one or more of penetrant JFC (fatty alcohol polyoxyethylene ether), penetrant T (diisooctyl maleate sulfonate), azone or silicone;

[0031] Further, the carrier is one, two or three of a solvent or a filler, and water is preferably deionized water;

[0032] Furthermore, the filler is selected from a mixture of one or more of kaolin, diatomaceous earth, bentonite, attapulgite, white carbon black, starch or light calcium carbonate;

[0033] The above substances are all commercially available.

[0034] The insecticidal composition of the present invention can be processed into any agriculturally acceptable dosage form;

[0035] Furthermore, the insecticide composition can be prepared into an agriculturally acceptable formulation, and the formulation is selected from a solid formulation and / or a liquid formulation;

[0036] Furthermore, the solid preparation includes powders, granules, pellets, tablets, strips, wettable powders, oil-dispersible powders, emulsion powders, water-dispersible granules, emulsion granules, water-dispersible tablets, soluble powders, soluble tablets or soluble granules;

[0037] Further, the liquid preparation includes a soluble solution, a soluble gel, an oil, a film-spreading oil, an emulsifiable concentrate, a latex, a dispersible liquid, an ointment, an aqueous emulsion, an oil emulsion, a microemulsion, a fat, a suspension, a microcapsule suspension, an oil suspension, a dispersible oil suspension, a suspoemulsion, a microcapsule suspension-suspension, a microcapsule suspension-water emulsion or a microcapsule suspension-suspoemulsion;

[0038] Furthermore, the solid preparation is selected from wettable powders and water dispersible granules; the liquid preparation is selected from emulsifiable concentrates, aqueous emulsions, microemulsions, suspensions, suspoemulsions, and dispersible oil suspensions;

[0039] Furthermore, the solid preparation is selected from wettable powders and water dispersible granules; the liquid preparation is selected from emulsifiable concentrates and suspensions.

[0040] The present invention also provides the use of the above insecticide composition in controlling lepidopteran pests;

[0041] Further, the lepidopteran pests include: Adoxophyes spp., Adoxophyes orana, Agrotis spp. (cutworm), Agrotis ipsilon (black cutworm), Alabama argillacea (cotton leafworm), Amorbia cuneana, Amyelosis transitella (navelorangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia g emma talis, Archips argyrospila (fruittreeleafroller), Archips rosana (rose leafroller), Agrotis spp. (black cutworm), Agrotis spp. (cotton leafworm), Amorbia cuneana, Amyelosis transitella (navelorangeworm), Anacamptodes defectaria, Anarsia lineatella (peach twig borer), Anomis sabulifera (jute looper), Anticarsia g emma talis, Archips argyrospila (fruittreeleafroller), Archips rosana (rose leafroller), Agrotis spp. (black cutworm ...grotis spp. (cotton leafworm), Agrotis spp. (cotton leafworm), Agrotis spp. (cotton leafworm), Agrotis spp. (cotton leafworm), Agrotis spp. leaf roller), Argyrotaenia spp. (tortricid moths), Argyrotaenia citrana (orange tortrix), Autographa gamma, Bonagota cranaodes, Borbo cinnara (rice leaf folder), Bucculatrix thurberiella (cotton leaf perforator), Caloptilia spp. (leaf miners), Capua reticulana, Carposina niponensis (peach fruit moth), Chilo spp., Chlumetia transversa (mango shoot borer), Choristoneura rosaceana (obliquebanded leaf roller),

[0042] leafroller), Chrysodeixis spp., Cnaphalocerusmedinalis (grass

[0043] leafroller), Colias spp., Conpomorpha cramerella, Cossus cossus (carpenter moth), Crambus spp. (sod webworms), Cydia funebrana (plum fruit moth), Cydia molesta (oriental fruit moth), Cydianignicana (pea moth), Cydia pomonella (codling moth), Darna diducta, Diaphania spp. (stem borers), Diatraea spp. (stalk borers), Diatraea saccharalis (sugarcane borer), Diatraea graniosella (southwester cornborer), Earias spp. (cotton bollworm), Earias insulata (Egyptian bollworm), Earias vitella (rough northern bollworm), Ecdytopophaaurantianum, Elasmopalpus lignosellus (lesser cornstalk borer), Epiphysias postruttana (light brown apple moth), Ephestia spp. (flour moths), Ephestia cautella (almond moth), Ephestia elutella (tobbaco moth), moth), Ephestia kuehniella (Mediterranean flour moth), Epimeces spp.), Epinotia aporema, Erionota thrax (bananaskipper), Eupoecilia ambiguella (grape berry moth), Euxoa auxiliaris (army cutworm), Feltia spp. (cutworms), Gortyna spp. (stemblerers), Grapholita molesta (Oriental fruit moth).

[0044] (oriental fruit moth), Hedylepta indicate (beanleaf webber), Helicoverpa sp p. (southworm), Helicoverpa armigera, Helicoverpa zea, Heliothis spp., Heliothis virescens, Hellula undalis (cabbage webworm), Indarbela spp. (root borers), Keiferia lycopersicella, Leucinodes orbonalis, Leucoptera malifoliella, Lithocollectis spp., Lobesia botrana (grape fruit moth), fruitmoth), Loxagrotis spp., Loxagrotis albicosta (western bean cutworm), Lymantria dispar (gypsy moth), Lyonetia clerkella (apple leaf miner), Mahasena corbetti (oil palm bagworm), Malacosoma spp.)(tent caterpillars), Mamestra brassicae(cabbage armyworm), Maruca testulalis(bean pod borer), Metisa plana, Mythimna unipuncta(true armyworm), Neoleucinodes elegantalis, Nymphula depunctalis, Operophtherabrumata, Ostrinia nubilalis(European corn borer), Oxydia vesulia, Pandemis cerasana(common currant tortrix), Pandemis heparana(brown apple tortrix), Papilio demodocus, Pectinophora gossypiella(pink bellworm), (bottomworm), Peridroma spp. (cutworm), Peridroma saucia (variegated cutworm), Perileucoptera coffeella (white coffee leafminer), Phthorimaea operculella (potato tuber moth), Phyllocnisitis citrella, Phyllonorycter spp., Pieris rapae, Plathypena scabra, Plodia interpunctella, Plutellaxylostella (diamondback moth), Polychrosis viteana (grapeberry moth), Prays endocarpa, Prays olive moth oleae) (olive moth), Pseudaletia spp.) (spodoptera), Pseudaletia unipunctata (armyworm), Pseudoplusia includes (, Rachiplusia nu, Scirpophaga incertulas, Sesamia spp. (stem borers), Sesamia inferens (pink rice stem borer), Sesamia nonagrioides, Setora nitens, Sitotroga cerealella (Angoumois grain moth), Sparganothis pilleriana, Spodoptera spp., Spodoptera exigua, Spodoptera fugiperda, Spodoptera oridania (southern armyworm), Synanthedon spp., Thecla basilides, Thermisia gemmatalis, Tineola bisselliella (webbing clothes moth), Trichoplusia ni (cabbage worm), Tuta absoluta;

[0045] Furthermore, the lepidopteran pests include Plutella xylostella, Spodoptera exigua, Spodoptera litura, Fall Armyworm, Chilo suppressalis, Cotton bollworm, and Pieris rapae;

[0046] The present invention also provides the above-mentioned insecticidal composition, which is applied to the pests to be controlled or the medium where they grow in an effective dose.

[0047] The beneficial effects of the present invention are:

[0048] 1) The insecticidal composition of the present invention has a synergistic effect on the control of lepidopteran pests at a certain mass ratio;

[0049] 2) Significantly reduce the amount of pesticides used and delay the resistance of lepidopteran pests to a single dose;

[0050] 3) Reduces environmental pollution and is safe for humans and animals. DETAILED DESCRIPTION

[0051] The present invention is further described below with reference to the examples. The percentages in the examples are all percentages by weight, but the present invention is not limited thereto.

[0052] The insecticidal composition of the present invention can be provided in the form of a formulation. It can be prepared into a suspension, water dispersible granules, wettable powder, dispersible oil suspension, etc. as needed. The content of the active ingredient in the composition of the present invention depends on the application amount when used alone, and also depends on the mixing ratio and the degree of synergistic effect. The optimal range of the active ingredient content varies according to the formulation type of the composition.

[0053] Preparation Example

[0054] Preparation Example 1:

[0055] 42% compound of formula (I)·oxazolidinone water dispersible granules (24:18)

[0056] Preparation formula: 24% of the compound of formula (I), 18% of fluazifop-dopamine, 7% of sodium lignin sulfonate, 7% of naphthalene sulfonate formaldehyde condensate, 2.5% of sodium dodecyl sulfate, 7% of white carbon black, 10% of starch, and the balance is made up of kaolin;

[0057] Preparation method: According to the formula ratio of the embodiment, the active ingredient is added to the carrier, and a surfactant and other functional additives are added thereto, mixed, and after air flow pulverization, 10-25% of water is added, and then kneading, granulation, drying and sieving are performed to obtain a water-dispersible granule product.

[0058] Preparation Example 2:

[0059] 46% formula (Ⅰ) compound·oxazolidinone wettable powder (26:20)

[0060] Preparation formula: 26% of the compound of formula (I), 20% of oxazolidinone, 4.5% of alkyl naphthalene sulfonate (Morwet EFW), 4% of block copolymer dispersant D-800, 3% of sodium alkyl polyoxyethylene ether sulfonate, 5.5% of sodium lignin sulfonate, and kaolin to make up the balance;

[0061] Preparation method: Active ingredients, other functional adjuvants and fillers are mixed according to the formula ratio, stirred evenly in a stirring kettle, and ground and mixed evenly for multiple times by a jet mill to prepare the wettable powder of the composition of the present invention.

[0062] Preparation Example 3:

[0063] 36% compound of formula (Ⅰ)·Cyclosulfuron wettable powder (28:8)

[0064] Preparation formula: 28% of the compound of formula (I), 8% of cyfluthrin, 4.5% of alkyl naphthalene sulfonate (Morwet EFW), 4% of block copolymer dispersant D-800, 3% of sodium alkyl polyoxyethylene ether sulfonate, 6.5% of starch, and the balance of kaolin;

[0065] Preparation method: Same as Preparation Example 2.

[0066] Preparation Example 4:

[0067] 25% formula (Ⅰ) compound·Cyprofenoxam suspension (20:5)

[0068] Preparation formula: 20% of the compound of formula (I), 5% of cyfluthrin, 3.5% of polyether, 3% of phenethylphenol polyether phosphate, 1.5% of naphthalenesulfonate (2020), 2% of dioctyl sodium succinate sulfonate, 1.1% of magnesium aluminum silicate, 0.25% of xanthan gum, 4.5% of glycerol, 0.02% of benzisothiazolinone, 0.5% of organosilicon defoamer, and the balance is made up of deionized water;

[0069] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in a reactor in sequence, water is added to mix evenly, and the suspension is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0070] Preparation Example 5:

[0071] 30% formula (Ⅰ) compound·oxazolidinone suspension concentrate (20:10)

[0072] Preparation formula: 20% of the compound of formula (I), 10% of oxazolidinone, 3.5% of polyether, 3% of phenethylphenol polyether phosphate salt, 1% of naphthalenesulfonate (2020), 2% of sodium dioctyl sulfosuccinate, 1.1% of magnesium aluminum silicate, 0.2% of xanthan gum, 5% of ethylene glycol, 0.02% of benzisothiazolinone, 0.5% of organosilicon defoamer, and the balance is made up of deionized water;

[0073] Preparation method: Same as Preparation Example 4.

[0074] Preparation Example 6:

[0075] 10% compound of formula (I)·Cyclosulfuron dispersible oil suspension (8:2)

[0076] Preparation formula: 8% of the compound of formula (I), 2% of cyfluthrin, 2% of succinate sulfonate, 12% of alkylaryl polyoxyethylene polyoxypropylene ether, 3% of fatty alcohol polyoxyethylene ether, 3% of calcium dodecylbenzene sulfonate, 1.5% of silicon dioxide, 0.5% of organic bentonite, 15% of 200# solvent oil, and the balance is made up of methyl oleate;

[0077] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in a reactor in sequence, and solvent oil is added to mix evenly. After high-speed shearing, wet sand grinding, and finally homogenous filtration, the dispersible oil suspension product is obtained.

[0078] Indoor biological activity assay:

[0079] The specific test methods are as follows:

[0080] Lepidoptera larvae: a combination of leaf and insect dipping;

[0081] Test insect age: Use sensitive populations raised indoors for multiple generations, and select healthy and uniform Lepidoptera 2nd instar larvae (no less than 60 per treatment).

[0082] Use tweezers to place fresh cabbage slices in the drug solution and immerse them for 10 seconds, then take them out. After the drug solution dries naturally, place the cabbage slices in a culture dish lined with moisturizing filter paper. Place the test insects in the drug solution for 5 seconds, absorb the excess drug solution with filter paper, and place the test insects in a culture dish with leaves immersed in the corresponding concentration.

[0083] Each treatment was repeated 4 times, and the blank treatment was used as the control. The treated test insects were placed in an artificial intelligence culture room at 26±1°C, a light duration of L:D=16h:8h, and a relative humidity of 60% for breeding.

[0084] After treatment with the pesticide, the mortality of the test insects was investigated at 48 hours. The criterion for judging the death of the test insects was obvious shrinkage of the insect body or inability to crawl normally after being pricked with a needle. The number of dead insects was recorded.

[0085] Data statistics and analysis:

[0086] According to the survey data, the adjusted mortality rate of each treatment was calculated using the following formula:

[0087]

[0088] Where:

[0089] P——mortality rate, in percentage (%);

[0090] K——indicates the number of dead insects, in units of heads;

[0091] N——represents the total number of insects treated, in heads.

[0092]

[0093] Where:

[0094] P1——adjusted mortality rate, in percentage (%);

[0095] P t——Treatment mortality rate, expressed as percentage (%);

[0096] P0——blank control mortality rate, in percentage (%).

[0097] Data statistics and analysis: If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made; if the control mortality rate is greater than 20%, the test needs to be repeated.

[0098] The data were processed by probability value analysis method; the DPS statistical analysis system was used to analyze the toxicity regression line and LC 50 The activity of the test agent on the biological test material was evaluated by using the value, 95% confidence limit and correlation coefficient r.

[0099] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0100]

[0101] Where:

[0102] ATI——Actual Toxicity Index of Mixture;

[0103] S——LC of standard pesticide 50 , the unit is milligrams per liter (mg / L);

[0104] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0105] TTI=TI A *P A +TI B *P B

[0106] Where:

[0107] TTI – Theoretical Toxicity Index of Mixtures;

[0108] TI A ——A: toxicity index of the agent;

[0109] P A ——The percentage of agent A in the mixture, in percentage (%);

[0110] TI B ——Toxicity index of agent B;

[0111] P B ——The percentage of agent B in the mixture, in percentage (%).

[0112]

[0113] Where:

[0114] CTC – Co-toxicity coefficient;

[0115] ATI——Actual Toxicity Index of Mixture;

[0116] TTI - Theoretical Toxicity Index of Mixture.

[0117] The co-toxicity coefficient of the combination CTC≥120 shows a synergistic effect; CTC≤80 shows an antagonistic effect; 80<CTC<120 shows an additive effect.

[0118] Indoor activity test of Pieris rapae

[0119] As shown in Table 1, oxazolidinone has a high toxicity to Pieris rapae, and its LC 50 The LC value of the compound of formula (I) against Pieris rapae is 2.446 mg / L. 50 It is 12.726mg / L.

[0120] When the weight ratio of the compound of formula (I) and oxazolidinone to Pieris rapae is 1:30-22:1, the co-toxicity coefficient is greater than 80, and the mixture of the two exhibits an additive or synergistic effect within this weight ratio range; when the compound of formula (I) and oxazolidinone are mixed to Pieris rapae in a weight ratio of 1:18-22:1, the co-toxicity coefficient is greater than 120, and the mixture of the two exhibits a synergistic effect within this weight ratio range.

[0121] Table 1 The results of the toxicity test of the compound of formula (I) and flubendiamide against Pieris rapae

[0122]

[0123] As shown in Table 2, cyfluthrin has a high toxicity to Pieris rapae, and its LC 50 The LC of the compound of formula (I) against Pieris rapae is 1.051 mg / L. 50 It is 12.726mg / L.

[0124] When the weight ratio of the compound of formula (I) and ciprofloxacin to Pieris rapae is 1:28 to 40:1, the co-toxicity coefficient is greater than 80, showing an additive or synergistic effect, and no antagonistic effect occurs; when the weight ratio of the compound of formula (I) and ciprofloxacin to Pieris rapae is 1:28 to 28:1, the co-toxicity coefficient is greater than 120, indicating that the mixture of the two exhibits a synergistic effect within this weight ratio range.

[0125] Table 2 The results of the toxicity test of the compound of formula (I) and cyfluthrin against Pieris rapae

[0126]

[0127] Field Trial on Controlling Cabbage Lobelia

[0128] Test crops: Chinese cabbage (Chengza No. 5);

[0129] Test target: Pieris rapae;

[0130] Test reference: Based on GB / T 17980.13-2000 "Guidelines for field efficacy tests (I): Pesticides for the control of lepidopteran larvae on cruciferous vegetables";

[0131] Test location: Chinese cabbage test field in Xiazhuang, Chengyang District, Qingdao City, Shandong Province;

[0132] Application equipment: 3WBS-16 electric backpack sprayer;

[0133] Trial time: August 12, 2023;

[0134] Test environment: The test site is flat, the soil texture is loam, and the land management level, soil fertility and irrigation conditions are consistent;

[0135] Test drug:

[0136] Table 3 Field test design and dosage

[0137]

[0138]

[0139] Weather: It was sunny on the day of application, and it was sunny or cloudy within 7 days after application.

[0140] Others: The cultivation and water and fertilizer conditions in each plot were uniform and consistent, and no fungicide, insecticide or herbicide was used in the first 30 days of the experiment.

[0141] Test method: Apply the pesticide once during the peak period of cabbage looper occurrence (mostly 2nd to 4th instar).

[0142] Plot size and repetition: random block arrangement, plot size 20m 2 , each treatment was repeated 4 times.

[0143] Survey method: Randomly sample five points in each plot, hang a sign on 4 plants at each point, investigate the number of cabbage loopers on all the cabbages, investigate the base number of insects before applying pesticides, and investigate the number of remaining insects 3 days and 10 days after applying pesticides.

[0144] Calculation formula and data analysis:

[0145]

[0146] Test results:

[0147] Safety: During the trial period and subsequent observations, the Chinese cabbage grew normally, with no obvious pesticide damage or other adverse phenomena occurring.

[0148] As can be seen from Table 4, 3 days after application, 30% of the compound of formula (I)·oxazolidinone suspension concentrate (20:10) and 36% of the compound of formula (I)·cyprodinil wettable powder (28:8) showed good rapid effect on cabbage loopers, with the control effects being 89.16% and 86.87% respectively, which were significantly higher than the control single agent.

[0149] Table 4 Field control effect of different pesticides on Chinese cabbage worms (3 days after pesticide application)

[0150]

[0151] Note: The above insect population base and control efficacy data are the average of 4 replicates, and the values ​​are rounded to two decimal places. Different letters after the control efficacy data in the same column indicate significant differences (P < 0.05).

[0152] As can be seen from Table 5, 10 days after application, 30% of the compound of formula (I)·oxazolidinone suspension concentrate (20:10) and 36% of the compound of formula (I)·cyprodinil wettable powder (28:8) showed good persistence against Chinese cabbage loopers, with the control effects being 94.64% and 93.25%, respectively, which were significantly higher than the control single agent.

[0153] Table 5 Field control effect of different pesticides on Chinese cabbage worms (10 days after application)

[0154]

[0155] Note: The above insect population base and control efficacy data are the average of 4 replicates, and the values ​​are rounded to two decimal places. Different letters after the control efficacy data in the same column indicate significant differences (P < 0.05).

[0156] Although the application describes specific embodiments in detail by means of examples, the disclosure of the application may adopt various modifications and alternative forms. However, it should be understood that the disclosure of the application is not limited to the disclosed specific forms. On the contrary, the disclosure of the application covers all modifications, equivalents and alternative forms within the scope of the disclosure of the application, and the scope of the application is limited by the attached claims and their legal equivalents.

Claims

1. An insecticidal composition, characterized in that: The active ingredients of the insecticide composition include active ingredient A and active ingredient B. Active ingredient A is a compound of formula (I) with the following structural formula: The active ingredient B is an arylisoxazoline insecticide.

2. The insecticidal composition according to claim 1, characterized in that The aromatic isoxazoline insecticide is selected from any one of fluazifop-flumizone and cyprodinil flumizone.

3. The insecticidal composition according to claim 1, characterized in that The mass ratio of the active ingredient A to the active ingredient B is 1:30 to 40:1; Preferably, the mass ratio of the active ingredient A to the active ingredient B is 1:28 to 28:

1.

4. The insecticidal composition according to claim 1, characterized in that The mass ratio of the compound of formula (I) to oxazolidinone is 1:30 to 22:1, and the mass ratio of the compound of formula (I) to cyprodinil is 1:28 to 40:1; Preferably, the mass ratio of the compound of formula (I) to fluazifop-flumizone is 1:18 to 22:1, and the mass ratio of the compound of formula (I) to fluazifop-flumizone is 1:28 to 28:

1.

5. The insecticidal composition according to claim 1, characterized in that: Based on the total weight of the insecticide composition being 100 wt%, the sum of the contents of the active ingredient A and the active ingredient B in the insecticide composition is 0.5 to 90 wt%; Preferably, the total content of the active ingredient A and the active ingredient B in the insecticide composition is 1 to 80 wt %.

6. The insecticidal composition according to claim 1, characterized in that The insecticide composition further comprises an adjuvant, which is selected from one or more of a wetting agent, a dispersant, an emulsifier, a thickener, a disintegrant, an antifreeze agent, a defoaming agent, a solvent, a stabilizer, a penetrant and a carrier.

7. The insecticidal composition according to claim 6, characterized in that The insecticide composition is prepared into a formulation form permitted in agriculture, and the formulation form is selected from a solid formulation and / or a liquid formulation; Preferably, the solid preparation is selected from wettable powders and water-dispersible granules; the liquid preparation is selected from emulsifiable concentrates, aqueous emulsions, microemulsions, suspensions, suspoemulsions, and dispersible oil suspensions.

8. Use of the insecticidal composition according to any one of claims 1 to 7 in controlling agricultural, forestry or horticultural herbivorous pests.

9. The use according to claim 8, characterized in that The herbivorous pests are lepidoptera pests; Preferably, the lepidopteran pests include Plutella xylostella, Spodoptera exigua, Spodoptera litura, Spodoptera frugiperda, Chilo suppressalis, Cotton bollworm, and Pieris rapae.

10. The use according to claim 8, characterized in that The insecticide composition is applied to the pests to be controlled or the medium where they grow in an effective dose.

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