Traditional Chinese medicine composition for diabetes as well as preparation method and application thereof

Abstract

The invention provides a traditional Chinese medicine composition for diabetes as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises 2-10 parts of cordyceps sinensis, 5-30 parts of lucid ganoderma, 30-50 parts of American ginseng, 10-50 parts of astragalus membranaceus, 10-40 parts of codonopsis pilosula, 5-35 parts of pseudo-ginseng, 20-70 parts of folium eriobotryae and 1-3 parts of liquorice. The pharmaceutical composition is a traditional Chinese medicine pill and other preparations prepared by combining cordyceps sinensis, lucid ganoderma, American ginseng, astragalus membranaceus, codonopsis pilosula, pseudo-ginseng, loquat leaves, liquorice and the like, the pharmaceutical composition is applied to clinical treatment of diabetes mellitus, and a large number of tests prove that the pharmaceutical composition has a remarkable curative effect and can stabilize and control blood sugar. The traditional Chinese medicine preparation is a pure traditional Chinese medicine preparation, has no side effect on human body, can regulate the balance of heart, liver, spleen, lung and kidney of human body, remove blood stasis, clear turbidity, quench thirst, tonify qi and dredge collaterals so as to achieve the purpose of reducing blood sugar, and is suitable for patients with hyperglycemia, diabetes and the like. The traditional Chinese medicine composition is good in medicine property, reasonable and simple in formula, easy to prepare, convenient to take, mild in medicine property, free of toxic and side effects, suitable for industrial production and high in application value.

Description

Technical Field

[0001] The present invention relates to the technical field of Chinese medicine formula, and in particular to a Chinese medicine composition for diabetes, a preparation method and application thereof. Background Art

[0002] With the improvement of people's living standards and changes in dietary structure, as well as my country's entry into an aging society, the number of patients with diabetes has also been increasing year by year. Diabetes is a metabolic disease caused by defective or impaired insulin secretion. It is directly manifested as high blood sugar. If the disease is not effectively controlled, it will also cause damage and functional impairment of other tissues and organs such as eyes, kidneys, and blood vessels. Since there are a large number of people with diabetes in my country, and this type of disease is the third largest non-communicable disease threatening human health after cardiovascular and tumors.

[0003] At present, Western medicine for the treatment of diabetes mainly includes the following categories: biguanides, sulfonylureas, glucosidase inhibitors, thiazolidinediones, and insulin. The above drugs have the characteristics of strong hypoglycemic effect and rapid onset, but they often lack overall coordination. Long-term use has obvious side effects on the liver and kidneys, and the hypoglycemic effect will indeed decrease, resulting in a certain degree of drug resistance.

[0004] In the field of traditional Chinese medicine treatment, the patent with the publication number "CN101491635B" and the name of "a traditional Chinese medicine composition for treating diabetes" discloses a traditional Chinese medicine preparation made of multiple raw materials. This technology uses a large number of raw materials, and the preparation method is cumbersome and complicated. Due to the large number of raw materials used, too many raw materials may cause other side effects. Therefore, it is not currently effective for many hyperglycemic patients. Summary of the invention

[0005] In view of this, in order to solve the problems existing in the technical background, the present invention proposes a Chinese medicine composition for diabetes, a preparation method and application thereof, and the specific technical scheme is as follows:

[0006] A Chinese medicine composition for diabetes, comprising the following components in parts by weight: cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis pilosula, notoginseng, loquat leaves, and liquorice;

[0007] 2-10 parts of cordyceps, 5-30 parts of ganoderma lucidum, 30-50 parts of American ginseng, 10-50 parts of astragalus, 10-40 parts of codonopsis, 5-35 parts of panax notoginseng, 20-70 parts of loquat leaves, and 1-3 parts of liquorice;

[0008] The method for preparing the Chinese medicine preparation of the Chinese medicine composition comprises the following steps:

[0009] Step 1: weigh the raw materials according to the above proportions, and dry cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis, notoginseng, loquat leaves, and licorice respectively, so that the water loss rate of each raw material is controlled below 70%, and the drying process is as follows: the thickness of the plate is controlled below 2 cm, the steam pressure is controlled to 0.02-0.20Mpa, and the temperature is 60°C±2°C for 2-3 hours. After drying, after passing through a 300-mesh sieve, the crushed materials are mixed and stirred evenly to obtain a mixture;

[0010] Step 2, placing the mixture into a heating container, adding 3-4 times the amount of water into the container, soaking for 1.5 hours, boiling over high heat, decocting over low heat for 1-2 hours, filtering through gauze to obtain filtrate 1 and medicinal residues; then adding 1-2 times the amount of water into the boiled medicinal residues, heating and boiling for 1-2 hours, cooling and obtaining filtrate 2, combining the two filtrates, heating, evaporating and concentrating into a thick paste with a relative density of 1.10-1.20, and setting aside;

[0011] Step 3, adding xylitol to the warm thick paste in step 2, and quickly stirring to mix the xylitol and the thick paste evenly;

[0012] Step 4: Place the mixture obtained in step 3 in a mold, press it into a cake shape, and then roll it into balls;

[0013] Step 5: Wrap the pills obtained in step 4 with cellophane and wax shell.

[0014] Furthermore, the diameter of the finished Chinese medicine pills in step 5 is 0.5-1 cm.

[0015] Furthermore, the cordyceps is 2 parts, ganoderma lucidum is 5 parts, American ginseng is 30 parts, astragalus is 10 parts, codonopsis is 10 parts, panax notoginseng is 5 parts, loquat leaves is 20 parts, and liquorice is 1 part.

[0016] Furthermore, the cordyceps is 10 parts, ganoderma lucidum is 30 parts, American ginseng is 50 parts, astragalus is 50 parts, codonopsis is 40 parts, panax notoginseng is 35 parts, loquat leaves is 70 parts, and liquorice is 3 parts.

[0017] Furthermore, the cordyceps 6 parts, ganoderma lucidum 16 parts, American ginseng 40 parts, astragalus 30 parts, codonopsis pilosula 25 parts, panax notoginseng 20 parts, loquat leaves 45 parts, liquorice 2 parts.

[0018] Furthermore, the preparation method also includes a process of adding excipients to prepare capsules or tablets.

[0019] The application of the Chinese medicine preparation obtained by the Chinese medicine composition in medicine for treating diabetes.

[0020] The above technical solution has the following beneficial effects:

[0021] The present invention is a Chinese medicine pill preparation made from cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis, notoginseng, loquat leaf, licorice and the like.

[0022] Cordyceps can regulate the balance of the five internal organs, resist kidney damage and tumors, have certain therapeutic effects on cardiovascular and cerebrovascular diseases, and enhance human immunity. It is a particularly nourishing medicine. When combined with other raw materials, it can not only show its own efficacy, but also enhance the efficacy of the matching medicine.

[0023] Lingzhi has the functions of strengthening the spleen and replenishing qi, nourishing the heart and calming the mind, nourishing and protecting the liver, improving eyesight and nourishing blood, etc. It can effectively enhance the body's immunity;

[0024] Astragalus, replenishes Qi and raises Yang, strengthens the exterior and stops sweating, produces body fluid and nourishes blood, relieves stagnation and arthritis, removes toxins and relieves stranguria, improves sexual function, and replenishes the kidney and strengthens the essence;

[0025] American ginseng can promote the production of body fluids and quench thirst, nourish yin, replenish vital energy, regulate blood pressure, dredge cardiovascular and cerebrovascular blockages, enhance vascular elasticity, promote protein synthesis, increase the amount of superoxide sodium enzyme in blood cells, lower blood sugar, and improve the body's disease resistance.

[0026] Codonopsis root, invigorates the spleen and lungs, nourishes blood and produces body fluid, resists ulcers, calms and relieves pain, promotes sleep, increases red blood cells and hemoglobin, resists bacteria and bacteria, assists in anti-tumor, and can regulate liver function when combined with Astragalus.

[0027] Panax notoginseng can replenish qi and blood, relax muscles, activate blood circulation and remove blood stasis, dredge cardiovascular and cerebrovascular vessels, remove waste from blood and blood vessel walls, relieve cerebral vascular sclerosis, and lower blood lipids and blood sugar.

[0028] Loquat leaves can clear the lungs and stop coughing, reduce adverse qi and stop vomiting, resolve phlegm and calm asthma, and regulate spleen and stomach disorders. When combined with the above ingredients, the function of loquat leaves is improved, and the effect on the lungs is particularly good. When the lungs are full of qi, the blood will circulate, and when the blood circulates, other organs will naturally balance.

[0029] Licorice can relieve cough and resolve phlegm, detoxify, alleviate the properties of drugs, balance the matching degree of various drugs so that they can play their respective effects and enhance the efficacy of various drugs after matching.

[0030] In the formation of diabetes, overeating is the initial root cause of diabetes. Eating too much increases the workload of the spleen and stomach, increases fat, and has a particularly great impact on the liver and kidneys. Over time, it accumulates in the stomach and intestines, forming a big belly and obesity, which makes the five internal organs unbalanced, leading to damage to the islet function, inability to secrete the insulin needed by the body, and gradually increase blood sugar. Over time, complications occur. The Chinese medicine composition of the present invention is treated from the following inventions to clean up intestinal garbage and make the intestines unobstructed. If qi is not stagnant, blood will stagnate, so it is necessary to replenish qi and nourish blood, dredge tendons and blood vessels, keep blood unobstructed, regulate the spleen and stomach to aid digestion, and balance The functions of the internal organs gradually restore the function of the pancreas, ensure the trace elements needed by the body, and promote body balance. Due to the recovery of various organs, insulin production is promoted. Whether it is blood lipids, blood pressure, or blood sugar, all complications are naturally effectively controlled and treated. It is applied to the clinical treatment of diabetes. The inventor has proved through a large number of experiments that the pharmaceutical composition of the present invention has significant therapeutic effects, can stabilize and control blood sugar, and effectively treat all complications of diabetes, including leg and foot ulcers, blurred vision, lowering blood sugar and lipids, balancing blood pressure, cerebral vascular sclerosis, restoring liver, kidney, spleen, and lung functions, and restoring pancreatic function.

[0031] The present invention is a pure Chinese medicine preparation, has no side effects on the human body, regulates the balance of the five internal organs of the human body, heart, liver, spleen, lungs and kidneys, removes blood stasis, clears turbidity, quenches thirst, replenishes qi and dredges, thereby achieving the purpose of lowering blood sugar, and is suitable for patients with hyperglycemia, diabetes and the like.

[0032] The invention has good medicinal properties, reasonable and simple formula, simple preparation, convenient administration, mild medicinal properties, no toxic and side effects, is suitable for industrial production, and has great application value. DETAILED DESCRIPTION

[0033] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] Example 1: A Chinese medicine composition for diabetes, comprising the following components by weight: cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis pilosula, notoginseng, loquat leaf, and liquorice;

[0035] 2 parts of Cordyceps sinensis, 5 parts of Ganoderma lucidum, 30 parts of American ginseng, 10 parts of Astragalus, 10 parts of Codonopsis pilosula, 5 parts of Panax notoginseng, 20 parts of loquat leaves, and 1 part of Licorice;

[0036] The preparation method of the Chinese medicine preparation of the Chinese medicine composition comprises the following steps: Step 1: weighing each raw material according to the above ratio, drying Cordyceps sinensis, Ganoderma lucidum, American ginseng, Astragalus, Codonopsis pilosula, Panax notoginseng, loquat leaf, and Licorice respectively, so that the water loss rate of each raw material is controlled below 70%, and the drying process is as follows: the thickness of the plate is controlled below 2 cm, the steam pressure is controlled at 0.02-0.20Mpa, and the temperature is 60℃±2℃ for 2-3 hours. After drying, the raw materials are passed through a 300-mesh sieve, and the dried raw materials are dried. The crushed materials are mixed and stirred evenly to obtain a mixture; step 2, placing the mixture into a heating container, adding 3-4 times the amount of water into the container, soaking for 1.5 hours, boiling over high heat, decocting over low heat for 1-2 hours, filtering through gauze to obtain filtrate 1 and medicinal residues; then adding 1-2 times the amount of water into the boiled medicinal residues, heating and boiling for 1-2 hours, cooling and obtaining filtrate 2, combining the two filtrates, heating, evaporating and concentrating to a thick paste with a relative density of 1.10-1.20, and setting aside;

[0037] Step 3, adding xylitol to the warm thick paste in step 2, and quickly stirring to mix the xylitol and the thick paste evenly;

[0038] Step 4: Place the mixture obtained in step 3 in a mold, press it into a cake shape, and then roll it into balls;

[0039] Step 5: Wrap the pills obtained in step 4 with cellophane and wax shell.

[0040] The Chinese medicine preparation prepared by the Chinese medicine composition is used in medicines for treating diabetes.

[0041] Example 2: A Chinese medicine composition for diabetes, comprising the following components by weight: cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis pilosula, notoginseng, loquat leaf, and liquorice;

[0042] 10 parts of Cordyceps sinensis, 30 parts of Ganoderma lucidum, 50 parts of American ginseng, 50 parts of Astragalus, 40 parts of Codonopsis pilosula, 35 parts of Panax notoginseng, 70 parts of loquat leaves, and 3 parts of Licorice;

[0043] The preparation method of the Chinese medicine preparation of the Chinese medicine composition comprises the following steps: Step 1: weighing each raw material according to the above ratio, drying Cordyceps sinensis, Ganoderma lucidum, American ginseng, Astragalus, Codonopsis pilosula, Panax notoginseng, loquat leaf, and Licorice respectively, so that the water loss rate of each raw material is controlled below 70%, and the drying process is as follows: the thickness of the plate is controlled below 2 cm, the steam pressure is controlled at 0.02-0.20Mpa, and the temperature is 60℃±2℃ for 2-3 hours. After drying, the raw materials are passed through a 300-mesh sieve, and the dried raw materials are dried. The crushed materials are mixed and stirred evenly to obtain a mixture; step 2, placing the mixture into a heating container, adding 3-4 times the amount of water into the container, soaking for 1.5 hours, boiling over high heat, decocting over low heat for 1-2 hours, filtering through gauze to obtain filtrate 1 and medicinal residues; then adding 1-2 times the amount of water into the boiled medicinal residues, heating and boiling for 1-2 hours, cooling and obtaining filtrate 2, combining the two filtrates, heating, evaporating and concentrating to a thick paste with a relative density of 1.10-1.20, and setting aside;

[0044] Step 3, adding xylitol to the warm thick paste in step 2, and quickly stirring to mix the xylitol and the thick paste evenly;

[0045] Step 4: Place the mixture obtained in step 3 in a mold, press it into a cake shape, and then roll it into balls;

[0046] Step 5: Wrap the pills obtained in step 4 with cellophane and wax shell.

[0047] The Chinese medicine preparation prepared by the Chinese medicine composition is used in medicines for treating diabetes.

[0048] Example 3: A Chinese medicine composition for diabetes, comprising the following components by weight: cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis pilosula, notoginseng, loquat leaf, and liquorice;

[0049] 10 parts of Cordyceps sinensis, 30 parts of Ganoderma lucidum, 50 parts of American ginseng, 50 parts of Astragalus, 40 parts of Codonopsis pilosula, 35 parts of Panax notoginseng, 70 parts of loquat leaves, and 3 parts of Licorice;

[0050] The preparation method of the Chinese medicine preparation of the Chinese medicine composition comprises the following steps: Step 1: weighing each raw material according to the above ratio, drying Cordyceps sinensis, Ganoderma lucidum, American ginseng, Astragalus, Codonopsis pilosula, Panax notoginseng, loquat leaf, and Licorice respectively, so that the water loss rate of each raw material is controlled below 70%, and the drying process is as follows: the thickness of the plate is controlled below 2 cm, the steam pressure is controlled at 0.02-0.20Mpa, and the temperature is 60℃±2℃ for 2-3 hours. After drying, the raw materials are passed through a 300-mesh sieve, and the dried raw materials are dried. The crushed materials are mixed and stirred evenly to obtain a mixture; step 2, placing the mixture into a heating container, adding 3-4 times the amount of water into the container, soaking for 1.5 hours, boiling over high heat, decocting over low heat for 1-2 hours, filtering through gauze to obtain filtrate 1 and medicinal residues; then adding 1-2 times the amount of water into the boiled medicinal residues, heating and boiling for 1-2 hours, cooling and obtaining filtrate 2, combining the two filtrates, heating, evaporating and concentrating to a thick paste with a relative density of 1.10-1.20, and setting aside;

[0051] Step 3, adding xylitol to the warm thick paste in step 2, and quickly stirring to mix the xylitol and the thick paste evenly;

[0052] Step 4: Place the mixture obtained in step 3 in a mold, press it into a cake shape, and then roll it into balls;

[0053] Step 5: Wrap the pills obtained in step 4 with cellophane and wax shell.

[0054] The Chinese medicine preparation prepared by the Chinese medicine composition is used in medicines for treating diabetes.

[0055] Experimental method: A hyperglycemic mouse model will be constructed.

[0056] Preparation process: 60 male mice aged 4-6 months were fed normally for 10 days and then randomly divided into a normal group (20 mice) and a modeling group (40 mice). From the 11th day, the mice in the normal group were fed with conventional feed, while the mice in the modeling group were fed with high-sugar and high-fat feed.

[0057] Experimental process: The modeling group mice were injected with 2% streptozotocin intraperitoneally once to establish the diabetes model, and the normal group rats were injected with citric acid buffer at a dosage of 0.1mL / 100g. After 72 hours, the tail vein blood of the modeling group mice was collected, and the blood sugar ≥16.7mmol / L was considered a successful model. Finally, there were 40 model animals. Except for the normal group, which was given a normal diet, the other groups continued to be fed with high-sugar and high-fat feed during the treatment process, and all were given drug treatment. The 40 successful modeling mice were randomly divided into four groups, 10 in each group, namely A, B, C, and D.

[0058] Group A was given about 5g of the Chinese medicine pills in Example 1, Group B was given about 5g of the Chinese medicine pills in Example 2, and Group C was given about 5g of the pills in Example 3, 5g each time, 2-3 times a day; the normal group and Group D were given an equal amount of physiological saline. All were administered 2-3 times a day for 60 consecutive days. On the 10th and 60th days of administration, glucose tolerance tests were performed on mice in each group. After 60 days of administration, the blood glucose values ​​and other data of mice in each group were detected, and the results are shown in Table 1.

[0059] Group Blood glucose level before treatment Blood glucose level after treatment A 27.89Mmol / L 13.89Mmol / L B 27.45Mmol / L 11.89Mmol / L C 27.75Mmol / L 16.89Mmol / L D 25.18Mmol / L 24.37Mmol / L Normal group 5.88Mmol / L 5.89Mmol / L

[0060] From the above data, it can be seen that the fasting blood glucose of mice taking the compositions in each embodiment of the present invention is significantly reduced compared with the normal group. The Chinese medicine composition provided by the present invention has a significant effect of lowering blood sugar. At the same time, the effect of Example 2 is better than that of Example 1 and Example 3. Comparing Example 1 with Example 3, both have certain therapeutic effects on the treatment of hyperglycemia, but the effect is not obvious compared with Example 2.

[0061] It is shown that the Chinese medicine composition provided by the present invention, which comprises 10 parts of cordyceps, 30 parts of ganoderma lucidum, 50 parts of American ginseng, 50 parts of astragalus, 40 parts of codonopsis pilosula, 35 parts of panax notoginseng, 70 parts of loquat leaves and 3 parts of liquorice, has the best effect.

[0062] The blood glucose values ​​after treatment in Table 1 are the average blood glucose values ​​2 hours after the meal.

[0063] The clinical treatment cases are as follows:

[0064] The present invention randomly selects 100 examples of diabetes cases, after taking the pill made by the Chinese medicine composition in the present embodiment 2, it is divided into three grades of marked effect, effective and weak effect, and the performance of marked effect is that there is no hyperglycemia throughout the day, 1 hour blood sugar 5.6-7.8mmol / L after the meal, and 2 hours blood sugar after the meal is at 4.4-6.7mmol / L. Effective performance is fasting blood sugar <9.6mmol / L, 2 hours blood sugar after the meal <9mmol / L, and 2 hours blood sugar after the meal is at 5-8mmol / L, and clinical manifestation is that symptoms alleviate, blood sugar is controlled, and complications alleviate, and the performance of weak effect is that blood sugar reduction is not obvious, and complication does not have obvious alleviation either. After treatment, 90 examples of marked effect, 9 examples of effective, 1 example of weak effect, and total effective rate 100%.

[0065] Treatment Example 1, information of diabetic patient: female, 52 years old, diagnosed with type 2 diabetes for 10 years. Before treatment, the fasting blood glucose value was 19.53mmol / L. After taking the hypoglycemic Chinese medicine composition provided in Example 2 in pills, 5-6g each time, three times a day, for 3 months, the fasting blood glucose value was 6mmol / L, which returned to the normal standard.

[0066] Treatment Example 2: Information of a diabetic patient, male, 62 years old, with a medical history of 16 years, fasting blood sugar of 12.8, which could only be maintained at about 10 after treatment with Chinese and Western medicine. After a few months, the fasting blood sugar rose to about 15-18, about 29 after a meal, and vision dropped sharply, itching all over the body, pain and numbness around the feet, and ulcers in both legs. He started taking insulin in 2021. Initially 18 units / day, gradually increased to 45 units / day after a few years. Unfortunately, he suffered from abdominal distension, less food and more stool, indigestion, dizziness, trance, and listlessness. Since taking the pills made of the hypoglycemic Chinese medicine composition of the present invention, the effect is remarkable, the eyes gradually become clear, the itching and ulceration of the skin gradually disappear, the blood pressure is normal, the immunity gradually improves, and the sexual function gradually recovers. After taking it for two months, the insulin injection was reduced to 18 units / day, and the insulin was completely stopped after 4 months. After 6 months, all normal values ​​were restored, and the fasting value was below 7.5mmol / L.

[0067] Treatment Example 3: Information of a diabetic patient, male, 68 years old, weighing 120kg, with a medical history of 13 years, mainly due to thirst, polydipsia, and intermittent oral ulcers for more than 2 years, blood sugar was 24.3mmol / L, urine sugar (+), diagnosed as type II diabetes, taking the pills prepared by the method of the present invention, 3 times a day, 5-6g each time, after taking the pills for 1 week, the symptoms of oral ulcers were significantly alleviated, and the fasting blood sugar was reduced to 15mmol / L after 1 month, and the fasting blood sugar was reduced to 11mmol / L after taking the pills of the present invention for 3 months. After 6 months, the fasting blood sugar value was 9.6mmol / L.

[0068] Treatment Example 4: Information of a diabetic patient, 52 years old, female, weighing 50kg, with a medical history of 8 years, the main causes are dry mouth, polydipsia, polyuria, dizziness, and mouth sores. The blood sugar is 26.3mmol / L, and the urine sugar is (+). The patient is diagnosed with type II diabetes. The patient takes the Yalian pills prepared by the method of the present invention, 3 times a day, 5-6g each time. After taking the medicine for 1 week, the symptoms of mouth sores are significantly relieved. After 3 weeks, the fasting blood sugar is reduced to 14.3mmol / L. After taking the medicine for 6 months, the fasting blood sugar is reduced to 9.6mmol / L. The fasting value is 6.7mmol / L after 9 months.

[0069] Treatment Example 5: Information of a diabetic patient, 40 years old, weighing 55 kg, with a medical history of 3 years. The main causes were dry mouth, polydipsia, weakness in the limbs, blurred vision, and sores in the mouth and tongue. The blood sugar was 22.9 mmol / L, and the urine sugar was (+). He was diagnosed with type 2 diabetes. He took the Yalian pills prepared by the method of the present invention, 3 times a day, 5-6 g each time. After taking the medicine for 1 week, the symptoms of sores in the mouth and tongue were relieved. The fasting blood sugar was 18 mmol / L. After 1 month, the fasting blood sugar dropped to 12.4 mmol / L. After 3 months, the fasting blood sugar dropped to 8 mmol / L. After 6 months, the fasting blood sugar value was 5.9 mmol / L.

[0070] The above five treatment cases all had no side effects, and the present invention had significant curative effect on diabetes. The herbal preparation is used for a course of treatment of two months, and 3-5 courses of treatment can cure the disease depending on the severity of the disease.

[0071] The present invention is a Chinese medicine pill preparation made from a combination of cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis, panax notoginseng, loquat leaves, licorice, etc., which is used in the clinical treatment of diabetes. The inventor has proved through a large number of experiments that the pharmaceutical composition of the present invention has significant therapeutic effects and can stabilize and control blood sugar.

[0072] The present invention is a pure Chinese medicine preparation, which has no side effects on the human body, regulates the balance of the five internal organs of the human body, heart, liver, spleen, lungs and kidneys, removes blood stasis, clears turbidity, quenches thirst, replenishes qi and dredges, thereby achieving the purpose of lowering blood sugar, and is suitable for patients with hyperglycemia, diabetes, etc. The preparation is a course of treatment of two months, and 3-5 courses of treatment can cure the disease depending on the severity of the lesion.

[0073] Overall, the invention has good medicinal properties, a reasonable and simple formula, simple preparation, convenient administration, mild medicinal properties, no toxic side effects, is suitable for industrial production, and has great application value.

[0074] The basic principles and main features of the present invention are described above. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for illustrating the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which shall fall within the scope of the present invention to be protected. The scope of protection of the invention shall be defined by the attached claims and their equivalents.

Claims

1. A Chinese medicine composition for diabetes, characterized in that: The composition comprises the following raw materials in parts by weight: The cordyceps is 2-10 parts, ganoderma lucidum is 5-30 parts, American ginseng is 30-50 parts, astragalus is 10-50 parts, codonopsis is 10-40 parts, panax notoginseng is 5-35 parts, loquat leaves is 20-70 parts, and liquorice is 1-3 parts.

2. A method for preparing a Chinese medicine preparation for diabetes, characterized in that: The Chinese medicine composition according to claim 1, wherein the preparation method comprises the following steps: Step 1: weigh the raw materials according to the above proportions, and dry cordyceps, ganoderma lucidum, American ginseng, astragalus, codonopsis, notoginseng, loquat leaves, and licorice respectively, so that the water loss rate of each raw material is controlled below 70%, and the drying process is as follows: the thickness of the plate is controlled below 2 cm, the steam pressure is controlled to 0.02-0.20Mpa, and the temperature is 60°C±2°C for 2-3 hours. After drying, after passing through a 300-mesh sieve, the crushed materials are mixed and stirred evenly to obtain a mixture; Step 2, placing the mixture into a heating container, adding 3-4 times the amount of water into the container, soaking for 1.5 hours, boiling over high heat, decocting over low heat for 1-2 hours, filtering through gauze to obtain filtrate 1 and medicinal residues; then adding 1-2 times the amount of water into the boiled medicinal residues, heating and boiling for 1-2 hours, cooling and obtaining filtrate 2, combining the two filtrates, heating, evaporating and concentrating into a thick paste with a relative density of 1.10-1.20, and setting aside; Step 3, adding xylitol to the warm thick paste in step 2, and quickly stirring to mix the xylitol and the thick paste evenly; Step 4: Place the mixture obtained in step 3 in a mold, press it into a cake shape, and then roll it into balls; Step 5: Package the pills obtained in step 4 with cellophane and wax shell.

3. A Chinese medicine composition for diabetes according to claim 1, characterized in that: The diameter of the finished Chinese medicine pills in step 5 is 0.5-1 cm.

4. A Chinese medicine composition for diabetes according to claim 1, characterized in that: The invention comprises 2 parts of cordyceps, 5 parts of ganoderma lucidum, 30 parts of American ginseng, 10 parts of astragalus, 10 parts of codonopsis pilosula, 5 parts of panax notoginseng, 20 parts of loquat leaves and 1 part of liquorice.

5. A Chinese medicine composition for diabetes according to claim 1, characterized in that: The invention comprises 10 parts of cordyceps, 30 parts of ganoderma lucidum, 50 parts of American ginseng, 50 parts of astragalus, 40 parts of codonopsis pilosula, 35 parts of panax notoginseng, 70 parts of loquat leaves and 3 parts of liquorice.

6. A Chinese medicine composition for diabetes according to claim 1, characterized in that: The invention comprises 6 parts of cordyceps, 16 parts of ganoderma lucidum, 40 parts of American ginseng, 30 parts of astragalus, 25 parts of codonopsis pilosula, 20 parts of panax notoginseng, 45 parts of loquat leaves and 2 parts of liquorice.

7. A Chinese medicine composition for diabetes according to claim 2, characterized in that: The preparation method also includes a process of adding excipients to prepare capsules or tablets.

8. Use of a Chinese medicine preparation prepared from the Chinese medicine composition according to claim 2 in medicine for treating diabetes.