Tumor sampling device convenient to sample
By designing a tumor sampling device including an annular isolation plate, a sampling mechanism, an expansion mechanism and a regulation mechanism, the problems of tumor sampling instability and basement membrane blockage in the prior art are solved, and the rapid and efficient tumor sampling is achieved without handheld sampling. Effect.
Patent Information
- Application Number
- CN202411772052.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-04
- Publication Date
- 2025-02-14
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing tumor sampling device requires a doctor to hold a sampler to sample the patient's tumor. When the tumor basement membrane is thick, the syringe of the sampling device cannot enter the inside of the tumor smoothly, resulting in unstable sampling and misjudgment of location.
A tumor sampling device including an annular isolation plate, a sampling mechanism, an expansion mechanism and a regulation mechanism is designed. The sampling mechanism creates negative pressure through the air extraction valve, the expansion mechanism clears the tumor base membrane through the expansion plate, and the adjustment mechanism provides cleaning and observation field through the micro camera and transparent cover, ensuring that the sampling tube can enter the inside of the tumor stably and accurately.
It realizes stable and rapid tumor sampling without a doctor's handheld sampler, avoids systolic tubes from entering other tissues or misalignment, and improves sampling efficiency and accuracy.
Smart Images

Figure CN119423856A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of tumor sampling equipment, and in particular to a tumor sampling device which is convenient for sampling. Background Art
[0002] At present, when screening tumors in medical research and clinical fields, it is necessary to sample the tumor for pathology. When doing tumor pathology, the tumor needs to be sampled first, and then the removed tumor is cut into appropriate sizes and made into inspection specimens. However, due to the various shapes of tumors, there are polyp-like, papillary, villous, nodular, lobed, cystic, cauliflower-like, mushroom-like, infiltrative mass-like, diffuse hypertrophic and ulcerative, etc., which leads to the various shapes of the cut tumors. When the traditional tumor sampling device is cutting and separating the tumor, it is impossible to accurately locate the tumor, which leads to the rolling of the tumor when cutting the tumor, and ultimately the tumor cannot be cut and separated quickly and efficiently, affecting the efficiency of tumor sampling.
[0003] Patent No. CN115444464A proposes a tumor sampling device, including a needle body, a needle, a hollow truncated cone-shaped cutting piece, a first push plate, a hollow first push rod and a reset spring; one side of the first push rod is connected to the needle, and the first push rod is connected to the needle, and the other side of the first push rod is detachably connected to the first push plate, the reset spring is sleeved on the first push rod, one side of the reset spring is connected to the inner side wall of the needle body, and the other side of the reset spring is connected to the first push plate, the cutting piece is installed on the inner side wall of the first push rod, the inner diameter of the cutting piece close to the first push plate is smaller than the inner diameter of the cutting piece away from the first push plate, and the inner diameter of the needle is larger than the inner diameter of the cutting piece. The present invention can avoid the problem of samples falling when medical staff take samples of tumors, and improve work efficiency.
[0004] The existing devices have the following problems when in use: First, the existing devices require doctors to hold a sampler to sample the patient's tumor when in use. This method has many unstable factors. When the doctor holds the sampler, his elbow is suspended in the air and cannot form a strong support, which easily causes the needle to pierce other tissues of the patient; Second, when the basement membrane of the tumor itself is thick or the proliferative tissue of the tumor overflows the basement membrane of the tumor, the former will cause the needle of the sampling device to encounter greater resistance when entering the tumor. When the doctor punctures the tumor with force, the needle may be misplaced or even penetrate the tumor. The latter will affect the doctor's judgment on the location of the tumor body, which is not conducive to effective sampling; Third, the existing devices are mostly used for tumors with good basement membranes when sampling, but different types of tumors have different shapes. In the absence of a field of view to observe the tumor, the doctor needs to rely on his own experience to judge the location of the tumor body and the location of the sampling point, which easily leads to the doctor misjudging the location where the tumor needs to be sampled due to the lack of field of view of the tumor when sampling the tumor.
[0005] Therefore, the present application provides a tumor sampling device that is convenient for sampling to meet the needs. Summary of the invention
[0006] The technical problem to be solved by the present invention is to provide a tumor sampling device that is convenient for sampling to solve the problem that the existing sampling device requires the doctor to hold a sampler to sample the patient's tumor and the needle of the sampling device cannot smoothly enter the tumor when the tumor basement membrane is thick.
[0007] In order to solve the above technical problems, the present invention provides the following technical solutions:
[0008] A tumor sampling device with convenient sampling comprises an annular isolation plate, a sampling mechanism is arranged inside the annular isolation plate, an expansion mechanism is arranged on one side of the sampling mechanism, and an adjustment mechanism is arranged on one side of the expansion mechanism;
[0009] A sampling mechanism, the sampling mechanism includes a first shell, a knob, a threaded sleeve, a swivel, a positioning rod, a collar, a threaded block, a sampling tube and an exhaust valve, the first shell is arranged on one side of the expansion mechanism, a knob is arranged on one side of the first shell, a threaded sleeve is fixedly connected to the bottom of the knob, a swivel is movably connected to the bottom of the threaded sleeve, a positioning rod is fixedly connected to the bottom of the swivel, a collar is fixedly connected to the bottom of the positioning rod, the threaded sleeve is threadedly sleeved on one side of the threaded block, a sampling tube is fixedly connected to one side of the threaded block, and an exhaust valve is arranged on one side of the sampling tube.
[0010] As a preferred scheme, the sampling mechanism also includes a limit plate, a partition, a first slider, a protrusion, a straight plate, a slide rail and a first slide groove. The limit plate is fixedly connected to the inside of the sampling tube, one side of the limit plate is fixedly connected to the partition, one side of the limit plate is movably connected to the first slider, the top of the first slider is fixedly connected to the protrusion, one side of the protrusion is fixedly connected to the straight plate, one side of the limit plate is fixedly connected to the slide rail, and the first slide groove is opened at the top of the sampling tube.
[0011] As a preferred solution, the first slider is movably mounted on one side of the first slide groove, and the first slider is also movably connected to the inside of the limit plate, and the partition separates the sampling tube into two cavities.
[0012] As a preferred solution, the positioning rod is movably connected to one side of the sampling tube, and the collar is movably sleeved on one side of the sampling tube.
[0013] As a preferred scheme, the expansion mechanism includes a first expansion arm, a second expansion arm, a first positioning axis and a second positioning axis. The first expansion arm and the second expansion arm are symmetrically arranged with the straight plate as the center. The first expansion arm and the second expansion arm include a first connecting rod, a first limiting hole, a first positioning plate, a first limiting column, a first connecting rod, a second limiting hole and an expansion plate. The first positioning axis and the second positioning axis are fixedly connected to the inside of the first shell. The first connecting rod is movably connected to one side of the collar. A first limiting hole is provided on one side of the first connecting rod. A first positioning plate is movably connected to one side of the first connecting rod. A first limiting column is fixedly connected to one side of the first positioning plate. A first limiting column is movably connected to one side of the first connecting rod. A second limiting hole is provided on one side of the first connecting rod. An expansion plate is fixedly installed on the end of the first connecting rod.
[0014] As a preferred solution, the first expansion arm and the second expansion arm also include a second positioning plate, a second limiting column, an air spring and a third positioning plate, the second positioning plate is fixedly connected to the bottom of the first limiting column, a second limiting column is arranged on the top of the second positioning plate, one side of the second positioning plate is fixedly connected to the third positioning plate, one side of the third positioning plate is fixedly installed with an air spring, and the air spring is fixedly installed on one side of the sampling tube.
[0015] As a preferred solution, the second limiting column is fixedly connected to the bottom of the first positioning plate, the second limiting column is movably connected to one side of the first connecting rod, and the third positioning plate is fixedly connected to one side of the first positioning plate.
[0016] As a preferred solution, the first connecting rod is rotatably connected to one side of the first positioning shaft with the first limiting hole as the center, and the first connecting rod is rotatably connected to one side of the second positioning shaft with the second limiting hole as the center.
[0017] As a preferred solution, the adjustment mechanism includes a positioning ring, a second shell, a second slide groove, a block, a positioning hole, a pull rod, a damping block, a metal spring and a second slider. The positioning ring is fixedly installed on the top of the annular isolation plate, one side of the positioning ring is fixedly connected to the second shell, a second slide groove is provided inside the second shell, one side of the second shell is fixedly connected to a block, one side of the block is provided with a positioning hole, one side of the positioning hole is movably sleeved with a pull rod, the bottom of the pull rod is fixedly connected to a damping block, a metal spring is fixedly connected between the damping block and the block, the metal spring is movably sleeved on one side of the pull rod, one side of the damping block is movably connected to the second slider, the second slider is fixedly installed on one side of the first shell, and the second slider is also movably connected to the inside of the second slide groove.
[0018] As a preferred solution, the adjustment mechanism also includes a light strip, a guide groove, a miniature camera, a transparent cover, a nozzle, a liquid storage tank, a top cover and a soft plug. The light strip is fixedly installed inside the annular isolation plate, the guide groove is opened at the bottom of the annular isolation plate, the miniature camera is fixedly installed inside the annular isolation plate, a transparent cover is arranged on one side of the miniature camera, a nozzle is arranged on the top of the transparent cover, one side of the nozzle is connected to the liquid storage tank, the top of the liquid storage tank is fixedly connected to the top cover, the top of the top cover is movably connected to the soft plug, the transparent cover is fixedly installed inside the annular isolation plate, and the liquid storage tank is fixedly installed on one side of the annular isolation plate.
[0019] Compared with the prior art, the present invention has at least the following beneficial effects:
[0020] 1. A tumor sampling device with convenient sampling, by setting a sampling tube, by setting an air extraction valve on one side of the sampling tube, the air inside the sampling tube is extracted by the air extraction valve before sampling, so that the inside of the sampling tube is negative pressure, when the sampling tube enters the tumor, the straight plate can be driven to move the first slider toward the inside of the limit plate by turning the knob, at this time, the tumor tissue outside the sampling tube is extracted into the inside of the sampling tube by the negative pressure inside the sampling tube, the sampling is convenient, and the annular isolation plate forms a support, so that the doctor does not need to hold the sample by hand, which improves the stability during sampling.
[0021] 2. A tumor sampling device with convenient sampling, which is provided with an expansion plate. The expansion plate can expand to both sides of the sampling tube to push the basement membrane on the top of the tumor to both sides, thereby preventing the basement membrane or the hyperplastic tissue of the tumor from blocking the sampling tube from entering the interior of the tumor to sample the tissue inside the tumor. Under the action of the air spring, the first connecting rod and the second connecting rod can reset themselves, and the operation is simple.
[0022] 3. A tumor sampling device with convenient sampling, which blocks the pus flowing out of the erosive tumor by setting a transparent cover, and continuously cleans the tumor and the transparent cover with physiological saline inside the liquid storage tank to ensure that the surface of the transparent cover will not be covered by pus, thereby ensuring the observation field of the micro camera, providing a good field of view for the sampling of the sampling mechanism, and performing accurate sampling. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] The accompanying drawings, which are incorporated herein and constitute a part of the specification, illustrate embodiments of the present disclosure and, together with the description, further serve to explain the principles of the present disclosure and to enable those skilled in the relevant art to make and use the present disclosure.
[0024] Figure 1 A schematic diagram of the main structure of a tumor sampling device that is convenient for sampling;
[0025] Figure 2A schematic diagram of the partial structure of a tumor sampling device that is convenient for sampling;
[0026] Figure 3 A schematic diagram of the main structure of a sampling mechanism of a tumor sampling device that is convenient for sampling;
[0027] Figure 4 It is a schematic diagram of the local structure of the sampling mechanism;
[0028] Figure 5 This is a schematic diagram of the main structure of the expansion mechanism;
[0029] Figure 6 It is a schematic diagram of the main structure of the regulating mechanism;
[0030] Figure 7 It is a schematic diagram of the local structure of the regulating mechanism;
[0031] Figure 8 This is a schematic diagram of the partial decomposition structure of the regulating mechanism.
[0032] 1. Annular isolation plate; 2. Sampling mechanism; 201. First housing; 202. Knob; 203. Threaded sleeve; 204. Rotating ring; 205. Positioning rod; 206. Collar; 207. Threaded block; 208. Sampling tube; 209. Air extraction valve; 210. Limiting plate; 211. Partition plate; 212. First slider; 213. Bump; 214. Straight plate; 215. Slide rail; 216. First slide groove; 3. Expansion mechanism; 31. First expansion arm; 32. Second expansion arm; 301. First connecting rod; 302. First limiting hole; 303. First positioning plate; 304. First limiting column; 305. Second connecting rod; 306. The second limiting hole; 307, expansion plate; 308, second positioning plate; 309, second limiting column; 310, air spring; 311, third positioning plate; 312, first positioning axis; 313, second positioning axis; 4, adjustment mechanism; 401, positioning ring; 402, second shell; 403, second slide groove; 404, block; 405, positioning hole; 406, pull rod; 407, damping block; 408, metal spring; 409, second slider; 410, light strip; 411, guide groove; 412, miniature camera; 413, transparent cover; 414, nozzle; 415, liquid storage tank; 416, top cover; 417, soft plug.
[0033] As shown in the figure, in order to clearly implement the structure of the embodiment of the present invention, specific structures and devices are marked in the figure, but this is only for illustrative purposes and is not intended to limit the present invention to the specific structure, device and environment. According to specific needs, ordinary technicians in this field can adjust or modify these devices and environments, and the adjustments or modifications made are still included in the scope of the attached claims. DETAILED DESCRIPTION
[0034] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0035] Example
[0036] like Figure 1 and Figure 2 As shown, an embodiment of the present invention provides a tumor sampling device with convenient sampling, comprising an annular isolation plate 1, a sampling mechanism 2 is arranged inside the annular isolation plate 1, an expansion mechanism 3 is arranged on one side of the sampling mechanism 2, and an adjustment mechanism 4 is arranged on one side of the expansion mechanism 3;
[0037] like Figure 3 , Figure 4 and Figure 5 As shown, the sampling mechanism 2 includes a first shell 201, a knob 202, a threaded sleeve 203, a swivel 204, a positioning rod 205, a collar 206, a threaded block 207, a sampling tube 208 and an air extraction valve 209. The first shell 201 is arranged on one side of the expansion mechanism 3, and a knob 202 is arranged on one side of the first shell 201. The bottom of the knob 202 is fixedly connected with the threaded sleeve 203, the bottom of the threaded sleeve 203 is movably connected with the swivel 204, the bottom of the swivel 204 is fixedly connected with the positioning rod 205, the bottom of the positioning rod 205 is fixedly connected with the collar 206, the threaded sleeve 203 is threadedly sleeved on one side of the threaded block 207, the one side of the threaded block 207 is fixedly connected with the sampling tube 208, and the one side of the sampling tube 208 is provided with an air extraction valve 209.
[0038] The sampling mechanism 2 also includes a limit plate 210, a partition 211, a first slider 212, a protrusion 213, a straight plate 214, a slide rail 215 and a first slide groove 216. The limit plate 210 is fixedly connected to the inside of the sampling tube 208, one side of the limit plate 210 is fixedly connected to the partition 211, one side of the limit plate 210 is movably connected to the first slider 212, the top of the first slider 212 is fixedly connected to the protrusion 213, one side of the protrusion 213 is fixedly connected to the straight plate 214, one side of the limit plate 210 is fixedly connected to the slide rail 215, and the first slide groove 216 is opened at the top of the sampling tube 208.
[0039] The first slider 212 is movably mounted on one side of the first slide groove 216 . The first slider 212 is also movably connected to the inside of the limiting plate 210 . The partition plate 211 divides the sampling tube 208 into two cavities.
[0040] The positioning rod 205 is movably connected to one side of the sampling tube 208 , and the collar 206 is movably sleeved on one side of the sampling tube 208 .
[0041] It is necessary to further explain that: in the normal state, the first slider 212 is located at one side of the first slide groove 216, the first slide groove 216 is closed, and the air in the sampling tube 208 is extracted through the air extraction valve 209, and the interior of the sampling tube 208 is in a negative pressure state. When it is necessary to sample the tumor, the annular isolation plate 1 is first aligned with the top of the tumor and placed, and then the position of the sampling tube 208 and the tumor where sampling is required is determined by the adjustment mechanism 4. After the sampling tube 208 is moved to the top of the tumor sampling location with the assistance of the adjustment mechanism 4, the relative position of the sampling mechanism 2 and the tumor is adjusted, and then the knob 202 is manually turned to drive the threaded sleeve 203 to rotate at the same time. At this time, the threaded sleeve 203 is spirally moved through the threaded groove opened between the threaded block 207. When the threaded sleeve 203 moves, the rotating ring 204 and the positioning rod 205 are driven to move along the sampling tube 208 toward the direction of the knob 202. At this time, as the positioning rod 205 moves, the positioning rod 205 drives the collar 206 and the straight plate 214 to drive the first slider 212 to slide inside the first slide groove 216 through the moving protrusion 213. When the first slider 212 moves to the inside of the limiting plate 210, the first slider 212 no longer blocks the outside air from entering the inside of the sampling tube 208. At this time, the sampling tube 208 enters the inside of the tumor. Under the action of negative pressure, the tumor sample is extracted into the inside of the sampling tube 208. Finally, the knob 202 is rotated in the opposite direction to finally drive the first slider 212 to reset to prevent the tumor sample from escaping from the cavity inside the sampling tube 208.
[0042] like Figure 3 and Figure 5 As shown, the expansion mechanism 3 includes a first expansion arm 31, a second expansion arm 32, a first positioning shaft 312 and a second positioning shaft 313. The first expansion arm 31 and the second expansion arm 32 are symmetrically arranged with the straight plate 214 as the center. The first expansion arm 31 and the second expansion arm 32 include a first connecting rod 301, a first limiting hole 302, a first positioning plate 303, a first limiting column 304, a first connecting rod 305, a second limiting hole 306 and an expansion plate 307. The first positioning shaft 312 and the second positioning shaft 313 are fixedly connected. Inside the first shell 201, the first connecting rod 301 is movably connected to one side of the ring 206, a first limiting hole 302 is opened on one side of the first connecting rod 301, a first positioning plate 303 is movably connected to one side of the first connecting rod 301, a first limiting column 304 is fixedly connected to one side of the first positioning plate 303, a first limiting column 304 is movably connected to one side of the first connecting rod 305, a second limiting hole 306 is opened on one side of the first connecting rod 305, and an expansion plate 307 is fixedly installed at the end of the first connecting rod 305.
[0043] The first expansion arm 31 and the second expansion arm 32 also include a second positioning plate 308, a second limiting column 309, an air spring 310 and a third positioning plate 311. The second positioning plate 308 is fixedly connected to the bottom of the first limiting column 304, and a second limiting column 309 is arranged on the top of the second positioning plate 308. One side of the second positioning plate 308 is fixedly connected to the third positioning plate 311, and one side of the third positioning plate 311 is fixedly installed with an air spring 310. The air spring 310 is fixedly installed on one side of the sampling tube 208.
[0044] The second limiting column 309 is fixedly connected to the bottom of the first positioning plate 303 , the second limiting column 309 is movably connected to one side of the first connecting rod 301 , and the third positioning plate 311 is fixedly connected to one side of the first positioning plate 303 .
[0045] The first connecting rod 301 is rotatably connected to one side of the first positioning shaft 312 with the first limiting hole 302 as the center, and the first connecting rod 305 is rotatably connected to one side of the second positioning shaft 313 with the second limiting hole 306 as the center.
[0046] It needs to be further explained that: when it is necessary to sample the tumor, with the cooperation of the adjustment mechanism 4, the expansion plate 307 is aligned with the top of the tumor, and then the first connecting rod 301 is driven to move in the direction of the knob 202 through the collar 206 on the sampling mechanism 2. At this time, the first connecting rod 301 is restricted by the first positioning shaft 312 inside the first limiting hole 302, and the first connecting rod 301 deflects with the first positioning shaft 312 as the axis. While deflecting, the first positioning shaft 312 moves from one side of the first limiting hole 302 to the other side, and at the same time At the same time, the second limiting column 309 and the third positioning plate 311 are driven to apply pressure to the air spring 310, and the first connecting rod 305 is further driven to rotate with the second positioning shaft 313 inside the second limiting hole 306 as the axis. At this time, the second positioning shaft 313 will move from one side of the second limiting hole 306 to the other side, and finally drive the expansion plate 307 to move away from the sampling tube 208. The tumor wound at the bottom of the sampling tube 208 is expanded by the expansion plate 307, so that the sampling tube 208 can enter the basement membrane of the tumor for sampling.
[0047] like Figure 6 , Figure 7 and Figure 8As shown, the adjustment mechanism 4 includes a positioning ring 401, a second shell 402, a second slide groove 403, a block 404, a positioning hole 405, a pull rod 406, a damping block 407, a metal spring 408 and a second slider 409. The positioning ring 401 is fixedly installed on the top of the annular isolation plate 1, one side of the positioning ring 401 is fixedly connected to the second shell 402, the second shell 402 is provided with a second slide groove 403, one side of the second shell 402 is fixedly connected to the block 404, one side of the block 404 A positioning hole 405 is opened on the side, a pull rod 406 is movably sleeved on one side of the positioning hole 405, a damping block 407 is fixedly connected to the bottom of the pull rod 406, a metal spring 408 is fixedly connected between the damping block 407 and the clamping block 404, the metal spring 408 is movably sleeved on one side of the pull rod 406, a second slider 409 is movably connected to one side of the damping block 407, the second slider 409 is fixedly installed on one side of the first shell 201, and the second slider 409 is also movably connected to the inside of the second slide groove 403.
[0048] The adjustment mechanism 4 also includes a light strip 410, a guide groove 411, a micro camera 412, a transparent cover 413, a nozzle 414, a liquid storage tank 415, a top cover 416 and a soft plug 417. The light strip 410 is fixedly installed inside the annular isolation plate 1, the guide groove 411 is opened at the bottom of the annular isolation plate 1, the micro camera 412 is fixedly installed inside the annular isolation plate 1, a transparent cover 413 is arranged on one side of the micro camera 412, a nozzle 414 is arranged on the top of the transparent cover 413, one side of the nozzle 414 is connected to the liquid storage tank 415, the top of the liquid storage tank 415 is fixedly connected to the top cover 416, the top of the top cover 416 is movably connected to the soft plug 417, the transparent cover 413 is fixedly installed inside the annular isolation plate 1, and the liquid storage tank 415 is fixedly installed on one side of the annular isolation plate 1.
[0049] It needs to be further explained that: in normal state, the soft plug 417 is fixed to the inside of the groove opened on the top of the top cover 416 by the friction between the bottom material and the top cover 416, and no saline is added to the inside of the liquid storage tank 415. When the basement membrane of the tumor to be sampled is ulcerated and pus inside the tumor flows out, the pus will block the field of view of the micro camera 412 set on the inner wall of the annular isolation plate 1. At this time, the pus is isolated from the micro camera 412 by the transparent cover 413, and the inside of the annular isolation plate 1 is illuminated by turning on the light strip 410. Finally, physiological saline is added to the inside of the liquid storage tank 415 by pulling out the soft plug 417. The physiological saline cleans the pus on the surface of the transparent cover 413 through the nozzle 414, and then the discarded physiological saline flows out of the annular isolation plate 1 through the guide groove 411, ensuring that when sampling the ulcerated tumor, the pus will not splash out of the annular isolation plate 1, and the position of the tumor is accurately located by the micro camera 412.
[0050] Working principle and use process of the present invention: During the use of the present invention, when a tumor sampling device with convenient sampling is used, first, when it is necessary to sample the tumor, with the cooperation of the adjustment mechanism 4, the expansion plate 307 is aligned with the top of the tumor, and then the first connecting rod 301 is driven to move in the direction of the knob 202 through the collar 206 on the sampling mechanism 2. At this time, the first connecting rod 301 is restricted by the first positioning shaft 312 inside the first limiting hole 302, and the first connecting rod 301 deflects with the first positioning shaft 312 as the axis. While deflecting, the first positioning shaft 312 will move from the first The limiting hole 302 moves from one side to the other side, and at the same time drives the second limiting column 309 and the third positioning plate 311 to apply pressure to the air spring 310, and further drives the first connecting rod 305 to rotate with the second positioning axis 313 inside the second limiting hole 306 as the axis. At this time, the second positioning axis 313 will move from one side of the second limiting hole 306 to the other side, and finally drive the expansion plate 307 to move away from the sampling tube 208. The tumor wound at the bottom of the sampling tube 208 is expanded by the expansion plate 307, so that the sampling tube 208 can enter the basement membrane of the tumor for sampling.
[0051] Next, the soft plug 417 is fixed to the inside of the groove opened on the top of the top cover 416 by the friction between the bottom material and the top cover 416. No saline is added to the inside of the liquid storage tank 415. When the basement membrane of the tumor to be sampled is ulcerated and pus inside the tumor flows out, the pus will block the field of view of the micro camera 412 set on the inner wall of the annular isolation plate 1. At this time, the pus is isolated from the micro camera 412 by the transparent cover 413, and the inside of the annular isolation plate 1 is illuminated by turning on the light strip 410. Finally, physiological saline is added to the inside of the liquid storage tank 415 by pulling out the soft plug 417. The physiological saline cleans the pus on the surface of the transparent cover 413 through the nozzle 414, and then the discarded physiological saline flows out of the annular isolation plate 1 through the guide groove 411, ensuring that when sampling the ulcerated tumor, the pus will not splash out of the annular isolation plate 1, and the position of the tumor is accurately located by the micro camera 412.
[0052] Next, the damping block 407 is driven to move toward the blocking block 404 by manually pulling the pull rod 406. At this time, the damping block 407 is separated from the second slider 409. At this time, the damping block 407 no longer restricts the second slider 409 by friction. The sampling mechanism 2 on one side of the second slider 409 can freely adjust its position. With the cooperation of the micro camera 412, the sampling mechanism 2 can be adjusted to a suitable height to sample the tumor.
[0053] Finally, the air inside the sampling tube 208 is extracted through the air extraction valve 209, and the interior of the sampling tube 208 is in a negative pressure state. When it is necessary to sample the tumor, the annular isolation plate 1 is aligned with the top of the tumor and placed, and then the sampling tube 208 and the location where the tumor needs to be sampled are determined by the adjustment mechanism 4. After the sampling tube 208 is moved to just above the tumor sampling location with the assistance of the adjustment mechanism 4, the relative position of the sampling mechanism 2 and the tumor is adjusted, and then the threaded sleeve 203 is driven to rotate at the same time by manually turning the knob 202. At this time, the threaded sleeve 203 is spirally moved through the threaded groove opened between the threaded block 207. When the threaded sleeve 203 moves, the rotating ring 204 and the fixed ring 204 are driven at the same time. The positioning rod 205 moves along the sampling tube 208 toward the direction of the knob 202. At this time, as the positioning rod 205 moves, the positioning rod 205 drives the collar 206 and the straight plate 214 to drive the first slider 212 to slide inside the first slide groove 216 through the moving protrusion 213. When the first slider 212 moves to the inside of the limiting plate 210, the first slider 212 no longer blocks the outside air from entering the inside of the sampling tube 208. At this time, the sampling tube 208 enters the inside of the tumor. Under the action of negative pressure, the tumor sample is extracted into the inside of the sampling tube 208. Finally, the knob 202 is rotated in the opposite direction to finally drive the first slider 212 to reset to prevent the tumor sample from escaping from the cavity inside the sampling tube 208.
[0054] Finally, it should be noted that the above are only preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. A tumor sampling device that is convenient for sampling, characterized in that: It comprises an annular isolation plate (1), a sampling mechanism (2) is arranged inside the annular isolation plate (1), an expansion mechanism (3) is arranged on one side of the sampling mechanism (2), and an adjustment mechanism (4) is arranged on one side of the expansion mechanism (3); The sampling mechanism (2) comprises a first housing (201), a knob (202), a threaded sleeve (203), a rotating ring (204), a positioning rod (205), a collar (206), a threaded block (207), a sampling tube (208) and an air extraction valve (209), wherein the first housing (201) is arranged on one side of the expansion mechanism (3), a knob (202) is arranged on one side of the first housing (201), and a bottom of the knob (202) is fixedly connected to A threaded sleeve (203), the bottom of which is movably connected to a swivel (204), the bottom of which is fixedly connected to a positioning rod (205), the bottom of which is fixedly connected to a collar (206), the threaded sleeve (203) is threadedly sleeved on one side of a threaded block (207), one side of which is fixedly connected to a sampling tube (208), and one side of the sampling tube (208) is provided with an air extraction valve (209).
2. A tumor sampling device with convenient sampling according to claim 1, characterized in that: The sampling mechanism (2) further comprises a limit plate (210), a partition plate (211), a first slider (212), a convex block (213), a straight plate (214), a slide rail (215) and a first slide groove (216); the limit plate (210) is fixedly connected to the inside of the sampling tube (208); one side of the limit plate (210) is fixedly connected to the partition plate (211); one side of the limit plate (210) is movably connected to the first slider (212); the top of the first slider (212) is fixedly connected to the convex block (213); one side of the convex block (213) is fixedly connected to the straight plate (214); one side of the limit plate (210) is fixedly connected to the slide rail (215); and the first slide groove (216) is opened at the top of the sampling tube (208).
3. A tumor sampling device with convenient sampling according to claim 2, characterized in that: The first slider (212) is movably mounted on one side of the first slide groove (216), and the first slider (212) is also movably connected to the inside of the limit plate (210). The partition (211) divides the sampling tube (208) into two cavities.
4. A tumor sampling device with convenient sampling according to claim 1, characterized in that: The positioning rod (205) is movably connected to one side of the sampling tube (208), and the sleeve ring (206) is movably sleeved on one side of the sampling tube (208).
5. A tumor sampling device with convenient sampling according to claim 1, characterized in that: The expansion mechanism (3) comprises a first expansion arm (31), a second expansion arm (32), a first positioning shaft (312) and a second positioning shaft (313); the first expansion arm (31) and the second expansion arm (32) are symmetrically arranged with the straight plate (214) as the center; the first expansion arm (31) and the second expansion arm (32) comprise a first connecting rod (301), a first limiting hole (302), a first positioning plate (303), a first limiting column (304), a first connecting rod (305), a second limiting hole (306) and an expansion plate (307); the first positioning shaft (312) and the second positioning shaft (313) are fixedly connected at Inside the first shell (201), the first connecting rod (301) is movably connected to one side of the ring (206), a first limiting hole (302) is opened on one side of the first connecting rod (301), a first positioning plate (303) is movably connected to one side of the first connecting rod (301), a first limiting column (304) is fixedly connected to one side of the first positioning plate (303), a first connecting rod (305) is movably connected to one side of the first limiting column (304), a second limiting hole (306) is opened on one side of the first connecting rod (305), and an expansion plate (307) is fixedly installed at the end of the first connecting rod (305).
6. A tumor sampling device for convenient sampling according to claim 5, characterized in that: The first expansion arm (31) and the second expansion arm (32) further include a second positioning plate (308), a second limiting column (309), an air spring (310) and a third positioning plate (311), wherein the second positioning plate (308) is fixedly connected to the bottom of the first limiting column (304), a second limiting column (309) is provided on the top of the second positioning plate (308), a third positioning plate (311) is fixedly connected to one side of the second positioning plate (308), an air spring (310) is fixedly installed on one side of the third positioning plate (311), and the air spring (310) is fixedly installed on one side of the sampling tube (208).
7. A tumor sampling device for convenient sampling according to claim 6, characterized in that: The second limiting column (309) is fixedly connected to the bottom of the first positioning plate (303), the second limiting column (309) is movably connected to one side of the first connecting rod (301), and the third positioning plate (311) is fixedly connected to one side of the first positioning plate (303).
8. The tumor sampling device with convenient sampling according to claim 5, characterized in that: The first connecting rod (301) is rotatably connected to one side of the first positioning shaft (312) with the first limiting hole (302) as the center, and the first connecting rod (305) is rotatably connected to one side of the second positioning shaft (313) with the second limiting hole (306) as the center.
9. The tumor sampling device with convenient sampling according to claim 1, characterized in that: The regulating mechanism (4) comprises a positioning ring (401), a second shell (402), a second slide groove (403), a block (404), a positioning hole (405), a pull rod (406), a damping block (407), a metal spring (408) and a second slider (409); the positioning ring (401) is fixedly mounted on the top of the annular isolation plate (1); one side of the positioning ring (401) is fixedly connected to the second shell (402); a second slide groove (403) is provided inside the second shell (402); one side of the second shell (402) is fixedly connected to the block (404); one side of the block (404) A positioning hole (405) is opened on the side, a pull rod (406) is movably sleeved on one side of the positioning hole (405), a damping block (407) is fixedly connected to the bottom of the pull rod (406), a metal spring (408) is fixedly connected between the damping block (407) and the clamping block (404), the metal spring (408) is movably sleeved on one side of the pull rod (406), a second slider (409) is movably connected to one side of the damping block (407), the second slider (409) is fixedly installed on one side of the first shell (201), and the second slider (409) is also movably connected to the inside of the second slide groove (403).
10. The tumor sampling device with convenient sampling according to claim 1, characterized in that: The adjustment mechanism (4) further comprises a light strip (410), a guide groove (411), a micro camera (412), a transparent cover (413), a nozzle (414), a liquid storage tank (415), a top cover (416) and a soft plug (417); the light strip (410) is fixedly mounted inside the annular isolation plate (1); the guide groove (411) is provided at the bottom of the annular isolation plate (1); the micro camera (412) is fixedly mounted inside the annular isolation plate (1); and the micro camera (414) is provided at the bottom of the annular isolation plate (1). A transparent cover (413) is provided on one side of the annular isolation plate (12), a nozzle (414) is provided on the top of the transparent cover (413), one side of the nozzle (414) is connected to a liquid storage tank (415), the top of the liquid storage tank (415) is fixedly connected to a top cover (416), the top of the top cover (416) is movably connected to a soft plug (417), the transparent cover (413) is fixedly installed inside the annular isolation plate (1), and the liquid storage tank (415) is fixedly installed on one side of the annular isolation plate (1).
Citation Information
Patent Citations
Tumor sampling device
CN115444464A