Whole herbal burn and wound prescription ointment

Through the design of the entire herbal burning trauma group paste, combined with cleaning and repair functions, the problems of cumbersome and adverse reactions in burn and scald treatment are solved, and rapid and safe wound healing and scar reduction are achieved.

CN119424531APending Publication Date: 2025-02-14GUANGXI HUAJIAN PHARMACEUTICAL TECHNOLOGY CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202411577517.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-06
Publication Date
2025-02-14

AI Technical Summary

Technical Problem

The existing treatment methods for burns and scalds need to be cleaned separately and applied to medicine. They are cumbersome and easy to cause infection. Commonly used drugs are highly irritating and lead to adverse reactions.

Method used

A full-herbal sausage paste was designed, including yellow dan, Panax notoginseng, Danzi, rhubarb, oyster, borneol, sesame oil, tea oil, beeswax, pearls, honeysuckle, dandelion and calcined gypsum, which were melted through hot water. and heating and melting process preparation, combining cleaning and repair functions to simplify processing steps.

Benefits of technology

While promoting wound healing, this ointment inhibits and kills pathogenic microorganisms, reduces scar formation, and achieves natural skin growth and healing. It has fewer toxicities and side effects and does not leave scars.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure HDA0005172950640000011
    Figure HDA0005172950640000011
  • Figure HDA0005172950640000021
    Figure HDA0005172950640000021
Patent Text Reader

Abstract

The invention relates to a whole herbal burn and wound formula ointment, which comprises the following raw materials by weight: 3-5 parts of yellow lead, 2-5 parts of pseudo-ginseng, 2-5 parts of cortex moutan, 3-6 parts of rheum officinale, 10-30 parts of oyster, 1-3 parts of borneol, 3-8 parts of sesame oil, 10-20 parts of tea oil, 10-20 parts of beeswax, 1-3 parts of pearl, 1-3 parts of honeysuckle, 1-3 parts of dandelion, and 3-5 parts of calcined gypsum. The components in the formula cooperate with one another, repair of the body is rapidly promoted, pathogenic microorganisms can be strongly inhibited and killed, and necrotic skin and muscular tissue of wounds can be automatically cleaned; the growth of granulation tissues of the wound surface is firstly promoted, and traceless repair is realized.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a whole-herb burn and wound formula ointment. Background Art

[0002] For severe burns and scalds with depth of Ⅱ0 to Ⅲ0, and for serious trauma, rotten and necrotic wounds, there is no better way except skin grafting and amputation. Once skin grafting is performed, it will bring new body trauma and sequelae. After recovery, patients will almost always be left with scars that affect body functions, large areas of severe burns, facial and body skin damage, and lifelong disability, leaving lifelong psychological trauma to patients. It also leaves a terrible shadow on the young hearts of innocent and happy little angels for life.

[0003] At present, when burns and scalds occur, wound cleaning and medication are two separate steps. If the cleaning is not timely, the wound will ulcerate and seriously affect skin repair. Therefore, repeated cleaning and medication are required, which is cumbersome. Improper wound treatment by patients themselves can easily cause infection and can only be carried out under the guidance or operation of professional medical staff. In addition, the commonly used burn and scald medicines themselves are irritating to a certain extent, and patients have large adverse reactions when using them. Therefore, the applicant has designed a herbal burn and wound formula ointment that combines the two functions of cleaning and repairing, simplifies the steps for patients to treat wounds, and the herbal formula is gentler and less irritating to the skin. Summary of the invention

[0004] In view of the above problems, the present invention provides a whole-herbal burn and wound ointment.

[0005] The present invention is achieved through the following technical solutions:

[0006] A herbal burn and wound ointment comprising the following raw materials in weight fraction ratio:

[0007] 1-3 parts of yellow ochre, 2-5 parts of Panax notoginseng, 2-5 parts of Cortex Moutan, 3-6 parts of Rhubarb, 10-30 parts of oyster, 1-3 parts of borneol, 3-8 parts of sesame oil, 10-20 parts of tea oil, 10-20 parts of beeswax, 1-3 parts of pearl, 1-3 parts of honeysuckle, 1-3 parts of dandelion and 3-5 parts of calcined gypsum.

[0008] Furthermore, the preparation method of the whole herbal burn and wound ointment is as follows:

[0009] (1) Pretreatment: Grind Panax notoginseng, Cortex Moutan, Radix Rhei, Pearl, Gypsum Fibrosum and Oyster into powder and pass through a 100-200 mesh sieve for later use;

[0010] (2) Dissolving with hot water: Heat water to 50-60°C and add the reserved Panax notoginseng, Cortex Moutan, Rhubarb and Pearl Powder. Heat to 90-100°C while stirring until completely dissolved. Cool the mixture to room temperature and sieve for later use.

[0011] (3) Heating and melting: add yellow lead, borneol, sesame oil, tea oil and beeswax to the mixed solution obtained in the above step, heat it to 160-200° C., stir and mix for 10-15 minutes, then slowly cool it down while stirring, add honeysuckle and dandelion powder, stir and mix, and then cool it down to obtain the whole herbal burn and wound ointment.

[0012] The functions of each ingredient in the formula are as follows:

[0013] Huangdan, the name of traditional Chinese medicine, is used in prescriptions as "lead dan, yellow dan, Guangdan, Dongdan", and is also known as "lead dan, Taodan, lead yellow, yellow dan, red dan, dan powder, Guodan, Zhufen, Songdan, Dongdan, Zhudan, Zhangdan, Taodan powder", etc. This product is lead tetraoxide processed from pure lead. It is made by refining lead, sulfur, saltpeter, etc. Huangdan has the effects of relieving itching and hemostasis, sterilizing and relieving pain, and healing sores and promoting tissue regeneration when used externally. It can also improve the adhesion of ointments.

[0014] The Chinese name of Panax notoginseng. It is the dried root of Panax notoginseng (Burk.) FHChen of the Araliaceae family. It has the effects of removing blood stasis and stopping bleeding, promoting blood circulation and relieving pain. It is mainly used to treat bleeding, traumatic injuries, and swelling and pain caused by blood stasis. The role of this component in the present invention is to use Panax notoginseng to reduce swelling, remove blood stasis, stop pain and stop bleeding.

[0015] Paeonia suffruticosa root bark is the dried root bark of the Ranunculaceae plant Paeonia suffruticosa. It is cylindrical or semi-cylindrical, with a gray-brown or yellow-brown outer surface, a plurality of horizontal long lenticels and fine root marks, a light gray-yellow or light brown inner surface, obvious fine longitudinal lines, common shiny crystals, hard and brittle. Modern research has shown that Paeonia suffruticosa root bark mainly contains chemical components such as paeonol, which is used to treat fever-induced rashes, hematemesis, epistaxis, carbuncle, ulcer, amenorrhea, dysmenorrhea, and injuries from falls. The effect of this component in the present invention is antibacterial and anti-inflammatory, which plays a role in cleaning wounds to avoid wound inflammation and ulceration.

[0016] Rhubarb, medicinal rhubarb is a herbaceous plant of the genus Rheum in the Polygonaceae family. Its roots and rhizomes are thick and yellow inside; the stems are thick and covered with short white hairs; the leaves are nearly round, the upper surface of the leaves is smooth and hairless, and the petioles are thick and cylindrical; the pedicels are slender, the flower disk is thin and petal-shaped; the fruits are oblong and elliptical; the seeds are broadly ovate; the flowering period is May-June; the fruiting period is August-September. Medicinal rhubarb is named rhubarb because its rhizomes are yellow. The role of this ingredient in the present invention is anti-inflammatory and analgesic, promoting wound healing and anti-fungal effects.

[0017] Oyster powder generally refers to oyster carbon powder. When used externally, it generally has the effects and functions of astringency and hemostasis, calcium supplementation, assisting in improving skin condition, assisting in preventing osteoporosis, and assisting in improving anemia. This ingredient in the present invention plays the role of hemostasis and utilizing the rich vitamins, amino acids, taurine and other nutrients in rhubarb. After proper use by patients, it can improve skin condition and achieve better skin repair effects.

[0018] Borneol, also known as borneol, is an organic compound with a cool feeling and a special aroma. Borneol plays the role of anti-inflammatory and analgesic, promoting wound healing and antibacterial and antipruritic in the present invention.

[0019] Sesame oil, tea oil, beeswax and calcined gypsum are necessary auxiliary materials for ointments.

[0020] Pearl powder contains a variety of amino acids and trace elements, which can help reduce skin pigmentation and reduce scar formation. Honeysuckle and dandelion have a certain aroma that can improve patients' acceptance of the ointment. In addition, honeysuckle and dandelion have anti-inflammatory and antibacterial effects.

[0021] The preparation process mentioned in the present invention is designed according to the water solubility characteristics of each component in the formula and the activity requirements of the effective components.

[0022] How to use

[0023] 1. Clean and disinfect the wound surface. For minor superficial wounds, apply plaster directly, cover with sterile gauze, and stick with medical tape;

[0024] 2. For ulcerated and larger wounds, remove necrotic tissue, clean the wound, spread the plaster on the wound with the thickness of a hard coin, cover it with sterile gauze, and fix it with medical tape or bandage; or evenly apply a thick layer of plaster on sterile gauze and then cover the wound. The medical patch is not fixed and should be changed once a day.

[0025] Compared with the prior art, the advantages and beneficial effects of the present invention are:

[0026] The herbal formula used in the present invention is less irritating to the skin, and the toxicity and side effects of the herbal formula are smaller than those of western medicine. The ingredients in the formula used in the present invention cooperate with each other to quickly promote the repair of the body, can strongly inhibit and kill pathogenic microorganisms, and automatically clean up necrotic skin and muscle tissue of the wound; first promote the growth of granulation tissue on the wound surface to evenly cover the wound surface; then promote the growth of normal skin tissue around the wound toward the center, naturally merge the inside and the outside, maintain the natural repair state of the body, grow smoothly and beautifully, without abnormal proliferation and skin dysfunction, and can achieve natural growth and healing of the skin to restore smooth skin quality without surgery or skin grafting, leaving no scars. BRIEF DESCRIPTION OF THE DRAWINGS Figure 1 This is a comparison chart of the repair effects of the present invention and silver sulfadiazine (SSD) ointment; Figure 2 The figure is a comparison of the antibacterial effects of the present invention and mupirocin. DETAILED DESCRIPTION

[0027] The present invention is further described in detail below by way of examples. These examples are only used to illustrate the present invention and do not limit the protection scope of the present invention.

[0028] Example 1

[0029] A herbal burn and wound ointment comprising the following raw materials in weight fraction ratio:

[0030] 1 part of yellow ochre, 2 parts of notoginseng, 2 parts of moutan bark, 3 parts of rhubarb, 10 parts of oyster, 1 part of borneol, 3 parts of sesame oil, 10 parts of tea oil, 10 parts of beeswax, 1 part of pearl, 1 part of honeysuckle, 1 part of dandelion and 3 parts of calcined gypsum.

[0031] Preferably, the whole herbal burn and wound ointment is prepared by the following method:

[0032] (1) Pretreatment: Grind Panax notoginseng, Cortex Moutan, Radix Rhei, Pearl, Gypsum Fibrosum and Oyster into powder and pass through a 100-mesh sieve for later use;

[0033] (2) Dissolving with hot water: Heat water to 50°C and add the reserved Panax notoginseng, Cortex Moutan, Rhubarb and Pearl Powder. Heat to 90°C while stirring until completely dissolved. Cool the mixture to room temperature and sieve for later use.

[0034] (3) Heating and melting: add yellow lead, borneol, sesame oil, tea oil and beeswax to the mixed solution obtained in the above step, heat to 160°C, stir and mix for 10 minutes, then slowly cool down while stirring, add honeysuckle and dandelion powder, stir and mix, and then cool to obtain the whole herbal burn and wound ointment.

[0035] Example 2

[0036] A herbal burn and wound ointment comprising the following raw materials in weight fraction ratio:

[0037] 2 parts of yellow ochre, 3 parts of Panax notoginseng, 3 parts of Cortex Moutan, 4 parts of Rhubarb, 15 parts of oyster, 2 parts of Borneolum, 5 parts of sesame oil, 15 parts of tea oil, 15 parts of beeswax, 2 parts of pearl, 2 parts of honeysuckle, 2 parts of dandelion and 2 parts of calcined gypsum.

[0038] Preferably, the whole herbal burn and wound ointment is prepared by the following method:

[0039] (1) Pretreatment: Grind Panax notoginseng, Cortex Moutan, Radix Rhei, Pearl, Gypsum Fibrosum and Oyster into powder and pass through a 150-mesh sieve for later use;

[0040] (2) Dissolving with hot water: Heat water to 55°C and add the reserved Panax notoginseng, Cortex Moutan, Rhubarb and Pearl Powder. Heat to 95°C while stirring until completely dissolved. Cool the mixture to room temperature and sieve for later use.

[0041] (3) Heating and melting: add yellow lead, borneol, sesame oil, tea oil and beeswax to the mixed solution obtained in the above step, heat to 200°C, stir and mix for 10 minutes, then slowly cool down while stirring, add honeysuckle and dandelion powder, stir and mix, and then cool to obtain the whole herbal burn and wound ointment.

[0042] Example 3

[0043] A herbal burn and wound ointment comprising the following raw materials in weight fraction ratio:

[0044] 3 parts of yellow ochre, 5 parts of Panax notoginseng, 5 parts of Cortex Moutan, 6 parts of Radix Rhei, 30 parts of oysters, 3 parts of Borneolum, 8 parts of sesame oil, 20 parts of tea oil, 20 parts of beeswax, 3 parts of pearls, 3 parts of honeysuckle, 3 parts of dandelions and 5 parts of calcined gypsum.

[0045] Preferably, the whole herbal burn and wound ointment is prepared by the following method:

[0046] (1) Pretreatment: Grind Panax notoginseng, Cortex Moutan, Radix Rhei, Pearl, Gypsum Calcium and Oyster into powder and pass through a 200-mesh sieve for later use;

[0047] (2) Dissolving with hot water: Heat water to 60°C and add the reserved Panax notoginseng, Cortex Moutan, Rhubarb and Pearl Powder. Heat to 100°C while stirring until completely dissolved. Cool the mixture to room temperature and sieve for later use.

[0048] (3) Heating and melting: add yellow lead, borneol, sesame oil, tea oil and beeswax to the mixed solution obtained in the above step, heat to 185°C, stir and mix for 15 minutes, then slowly cool down while stirring, add honeysuckle and dandelion powder, stir and mix, and then cool to obtain the whole herbal burn and wound ointment.

[0049] Effective experiments:

[0050] The applicant collected clinical data of patients with small-area burns and compared the skin repair of patients with the same number of people and the same degree of burns using the present invention and using silver sulfadiazine. The results are as follows:

[0051] The X-axis is time, and the Y-axis is the degree of skin repair (%)

[0052] It can be seen that the skin repair effect of the present invention within 366 hours is better than that of the traditional burn medicine silver sulfadiazine.

[0053] The applicant also compared the antibacterial effect by setting up an experimental group and a control group. The present invention and mupirocin were added to two culture media of the same bacterial species and the same colony number in the laboratory for comparison, and samples were taken at three time points of 0 hours, 24 hours and 48 hours to compare the antibacterial effect. The results are as follows Figure 2 .

[0054] The X-axis is the sampling time, and the Y-axis is the average bacterial count (CFU / mL)

[0055] It can be seen from the figure that the antibacterial effect of the present invention is significantly better than that of mupirocin.

Claims

1. A herbal burn and wound ointment, characterized in that: Contains the following raw materials in weight fraction ratio: 1-3 parts of yellow ochre, 2-5 parts of Panax notoginseng, 2-5 parts of Cortex Moutan, 3-6 parts of Rhubarb, 10-30 parts of oyster, 1-3 parts of borneol, 3-8 parts of sesame oil, 10-20 parts of tea oil, 10-20 parts of beeswax, 1-3 parts of pearl, 1-3 parts of honeysuckle, 1-3 parts of dandelion and 3-5 parts of calcined gypsum.

2. The herbal burn and wound ointment according to claim 1, characterized in that: The preparation method is as follows: (1) Pretreatment: Grind Panax notoginseng, Cortex Moutan, Radix Rhei, Pearl, Gypsum Calcium and Oyster into powder and pass through a 100-200 mesh sieve for later use; (2) Dissolving with hot water: Heat water to 50-60°C and add the reserved Panax notoginseng, Cortex Moutan, Rhubarb and Pearl Powder. Heat to 90-100°C while stirring until completely dissolved. Cool the mixture to room temperature and sieve for later use. (3) Heating and melting: add yellow lead, borneol, sesame oil, tea oil and beeswax to the mixed solution obtained in the above step, heat it to 160-200° C., stir and mix for 10-15 minutes, then slowly cool it down while stirring, add honeysuckle and dandelion powder, stir and mix, and then cool it down to obtain the whole herbal burn and wound ointment.