Energy-saving grinding device for ganciclovir crude product before impurity removal

Abstract

The invention discloses an energy-saving grinding device before impurity removal of a ganciclovir crude product, belongs to the technical field of ganciclovir grinding, and aims to solve the problems of high energy consumption and long time during grinding of the ganciclovir crude product. The device comprises a shell and an inner cylinder arranged in the shell, and further comprises a grinding roller arranged in the inner cylinder, the inner cylinder is composed of a third grinding cylinder, a second grinding cylinder, a first grinding cylinder and a collecting disc, the diameters of the third grinding cylinder, the second grinding cylinder and the first grinding cylinder are gradually decreased, and the inner cylinder is matched with the grinding roller which is fixedly connected and provided with inclined grinding teeth on the outer edge to form a multi-layer progressive grinding space; the grinding teeth incline and rotate to generate an inclined downward extrusion force, so that the material crushing is more efficient, the grinding degree can be accurately controlled, and the material is sequentially subjected to coarse grinding and accurate grinding, the motor drives the grinding roller to rotate forwards and backwards, and the material transfer and circulation are realized through the cooperation of the linkage mechanism and the discharging control mechanism, the anticlockwise rotation grinding of the motor and the clockwise rotation of the motor; the overall grinding efficiency is greatly improved, the grinding period is effectively shortened, and the efficiency is improved compared with traditional grinding equipment.

Description

Technical Field

[0001] The invention relates to the technical field of ganciclovir grinding, in particular to an energy-saving grinding device for ganciclovir crude products before impurity removal. Background Art

[0002] Ganciclovir is an important antiviral drug with a wide range of applications in the pharmaceutical field. Its crude product is usually a preliminary product obtained during chemical synthesis, contains a lot of impurities and the particle state is often uneven, and cannot be directly used in the subsequent key links of pharmaceutical production.

[0003] In the production process of ganciclovir, grinding the crude ganciclovir is a key step, which aims to reduce the particle size and increase the specific surface area, so as to facilitate the subsequent impurity removal, refining and other processes. The traditional grinding method mainly relies on equipment such as ball mills and vibration mills. The ball mill drives the grinding balls to impact and rub the crude product through the rotation of the grinding jar. Although it can achieve a certain degree of grinding effect, it has the problems of high energy consumption and long grinding time. Summary of the invention

[0004] The object of the present invention is to provide an energy-saving grinding device for ganciclovir crude product before impurity removal, which solves the problem of high energy consumption and long time in grinding of ganciclovir crude product in the background art.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: an energy-saving grinding device for ganciclovir crude product before impurity removal, comprising an outer shell and an inner cylinder arranged inside the outer shell, and also comprising a grinding roller arranged inside the inner cylinder, wherein the inner cylinder comprises a third grinding cylinder, a second grinding cylinder, a first grinding cylinder and a collecting plate connected in sequence from top to bottom, and the diameters of the first grinding cylinder, the second grinding cylinder and the third grinding cylinder decrease upward in sequence, the grinding roller comprises a first grinding disc, a second grinding disc and a third grinding disc which are respectively rotatably connected to the insides of the first grinding cylinder, the second grinding cylinder and the third grinding cylinder, and the first grinding disc, the second grinding disc and the third grinding disc are fixedly connected, the outer edges of the first grinding disc, the second grinding disc and the third grinding disc are evenly distributed with grinding teeth, and the grinding teeth are arranged obliquely, and one side of the grinding teeth is connected to the first grinding disc, the second grinding disc and the third grinding disc. The outer wall of the third grinding disk has a smooth transition, and the other side of the grinding teeth is provided with a slope with the outer walls of the first grinding disk, the second grinding disk and the third grinding disk. Gaps for grinding are formed between the first grinding disk, the second grinding disk and the third grinding disk and the inner walls of the first grinding cylinder, the second grinding cylinder and the third grinding cylinder. The gap between the third grinding disk and the third grinding cylinder is larger than the gap between the second grinding disk and the second grinding cylinder, and the gap between the first grinding disk and the first grinding cylinder. A motor is arranged below the grinding roller inside the shell, and the motor is used to drive the grinding roller to rotate forward and reversely. A linkage mechanism is arranged outside the grinding roller inside the shell, and a discharging control mechanism and a positioning plate are arranged above the grinding roller inside the shell, wherein the linkage mechanism and the discharging control mechanism are used to control the grinding of materials from top to bottom in sequence, and the positioning plate is used to position the discharging control mechanism.

[0006] Furthermore, a second retaining ring is fixedly connected to the bottom of the third grinding cylinder, a gap is provided between the second retaining ring and the second grinding cylinder, the outer lower part of the second retaining ring is fixedly connected to the second grinding cylinder through a fixing piece, the bottom of the second grinding cylinder is fixedly connected to the first retaining ring, a gap is provided between the first retaining ring and the first grinding cylinder, the outer lower part of the first retaining ring is fixedly connected to the first grinding cylinder through a fixing piece, and the bottom of the first grinding cylinder is fixedly connected to the collecting plate.

[0007] Furthermore, an inclined collecting groove is provided inside the collecting plate, a discharge pipe is provided outside the collecting plate, and one end of the discharge pipe is connected to the collecting groove, and the other end of the discharge pipe extends to the outside of the outer shell; a dividing plate is also provided on the top of the third grinding cylinder, a gap is provided between the dividing plate and the third grinding cylinder, the dividing plate is fixedly connected to the third grinding cylinder through a fixing part, and the dividing plate and the third grinding plate are not fixed.

[0008] Furthermore, the output end of the motor is fixedly connected to a driving rod, the top of the driving rod is fixedly connected to the middle of the bottom of the first grinding disk, the outside of the driving rod is provided with an external thread, and the external thread is a threaded shape protruding outward; the linkage mechanism includes a movable frame, the movable frame is L-shaped, and the movable frame is provided with two groups. A threaded seat is provided at the connection between the two groups of movable frames, the threaded seat is installed on the outside of the driving rod, and the threaded seat corresponds to the driving rod, a compression spring is installed between the bottom of the movable frame and the inner wall of the bottom of the outer shell, and a connecting frame is fixedly installed on the inner side of the top of the movable frame.

[0009] Furthermore, the discharge control mechanism includes a first baffle ring, a second baffle ring and a third baffle ring which are arranged in sequence from the inside to the outside, wherein the bottoms of the first baffle ring, the second baffle ring and the third baffle ring are the tops of the first grinding cylinder, the second grinding cylinder and the third grinding cylinder respectively, and the connecting frame is fixedly connected to the first baffle ring, the second baffle ring and the third baffle ring through a slider, and the first baffle ring, the second baffle ring and the third baffle ring are slidably connected to the lower part of the inner part of the positioning plate, and a feed pipe extending to the outside of the outer shell is provided at the top of the positioning plate, and a groove running through the upper and lower parts is provided in the middle of the positioning plate.

[0010] Furthermore, the material discharging control mechanism also includes a first material stop ring and a second material stop ring slidably connected under the positioning plate, wherein the first material stop ring and the second material stop ring are respectively located on the inner sides of the first stop ring and the second stop ring, and correspond to the outer walls of the first stop ring and the second stop ring.

[0011] Furthermore, a transmission mechanism is provided between the first retaining ring and the first material retaining ring, and between the second retaining ring and the second material retaining ring.

[0012] Furthermore, the transmission mechanism includes a second tooth groove arranged on the inner walls of the first retaining ring and the second retaining ring, a spur gear arranged on the outer walls of the first retaining ring and the second retaining ring, and also includes a first tooth groove installed under the positioning plate through a mounting frame, and the first tooth groove is meshingly connected between the second tooth groove and the spur gear.

[0013] Compared with the prior art, the present invention has the following beneficial effects:

[0014] The energy-saving grinding device for ganciclovir crude product before impurity removal provided by the present invention comprises an inner cylinder composed of a third grinding cylinder, a second grinding cylinder, a first grinding cylinder and a collecting plate with decreasing diameters, which cooperates with a grinding roller which is fixedly connected and has inclined grinding teeth on the outer edge to form a multi-level progressive grinding space. The inclination and rotation of the grinding teeth generate an oblique downward extrusion force, which makes material crushing more efficient, and can accurately control the degree of grinding so that the material is sequentially subjected to coarse grinding and fine grinding. The motor drives the grinding roller to rotate in both directions, and the motor grinds by counterclockwise rotation through the cooperation of the linkage mechanism and the material discharging control mechanism, and realizes material transfer and circulation by clockwise rotation, thereby greatly improving the overall grinding efficiency and effectively shortening the grinding cycle. Compared with traditional grinding equipment, the efficiency is improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0016] Figure 2 It is a disassembled diagram of the overall structure of the present invention;

[0017] Figure 3 It is a cross-sectional view of the inner cylinder, grinding roller, motor and positioning plate structure of the present invention;

[0018] Figure 4 This is a structural exploded view of the inner cylinder, grinding roller, motor, linkage mechanism, discharge control mechanism and positioning plate of the present invention;

[0019] Figure 5 It is an exploded view of the inner cylinder, grinding roller and motor structure of the present invention;

[0020] Figure 6 It is a cross-sectional view of the inner cylinder and the grinding roller of the present invention;

[0021] Figure 7 It is a schematic diagram of the linkage mechanism and the material discharging control mechanism of the present invention;

[0022] Figure 8 It is a plan cross-sectional view of the linkage mechanism, the material discharging control mechanism and the positioning plate structure of the present invention.

[0023] In the figure: 1. outer shell; 2. inner cylinder; 21. first grinding cylinder; 22. second grinding cylinder; 221. first retaining ring; 23. third grinding cylinder; 231. second retaining ring; 24. collecting plate; 241. collecting trough; 242. discharge pipe; 3. grinding roller; 31. first grinding disc; 32. second grinding disc; 33. third grinding disc; 34. grinding teeth; 35. material distribution disc; 4. motor; 41. driving rod; 42. external thread; 5. linkage mechanism; 51. movable frame; 52. threaded seat; 53. compression spring; 54. connecting frame; 55. slider; 6. discharge control mechanism; 61. first retaining ring; 62. second retaining ring; 63. third retaining ring; 64. first retaining ring; 65. second retaining ring; 66. transmission mechanism; 661. first tooth groove; 662. second tooth groove; 663. spur gear; 7. positioning plate; 71. feed pipe. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0025] In order to solve the technical problem of high energy consumption and long time in grinding of crude ganciclovir, such as Figure 1-Figure 8 As shown, the following preferred technical solutions are provided:

[0026] like Figure 1-Figure 3 As shown in FIG. 1 , the energy-saving grinding device for ganciclovir crude product before impurity removal comprises a housing 1 and an inner cylinder 2 arranged inside the housing 1, and further comprises a grinding roller 3 arranged inside the inner cylinder 2. Figure 4-Figure 5 As shown, the inner cylinder 2 includes a third grinding cylinder 23, a second grinding cylinder 22, a first grinding cylinder 21 and a collecting plate 24 connected in sequence from top to bottom, and the diameters of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23 decrease upward in sequence, and the grinding roller 3 includes a first grinding disc 31, a second grinding disc 32 and a third grinding disc 33 that are rotatably connected to the inside of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23, respectively, and the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33 are fixedly connected, and the first grinding disc 31 The outer edges of the second grinding disc 32 and the third grinding disc 33 are evenly distributed with grinding teeth 34, and the grinding teeth 34 are inclined. One side of the grinding teeth 34 has a smooth transition with the outer walls of the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33, and the other side of the grinding teeth 34 has a slope with the outer walls of the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33. A gap for grinding is formed between the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33 and the inner walls of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23, as shown in FIG. Figure 6As shown, the gap between the third grinding disc 33 and the third grinding cylinder 23 is larger than the gap between the second grinding disc 32 and the second grinding cylinder 22, which is larger than the gap between the first grinding disc 31 and the first grinding cylinder 21. A motor 4 is arranged inside the housing 1 below the grinding roller 3. The motor 4 is used to drive the grinding roller 3 to rotate forward and reversely. A linkage mechanism 5 is arranged outside the grinding roller 3 inside the housing 1. A discharging control mechanism 6 and a positioning plate 7 are arranged above the grinding roller 3 inside the housing 1. The linkage mechanism 5 and the discharging control mechanism 6 are used to control the material to be ground from top to bottom in sequence. The positioning plate 7 is used to position the discharging control mechanism 6. When the motor 4 drives the grinding roller 3 to rotate counterclockwise, the first grinding disc 31 and the second grinding disc 32 are rotated counterclockwise. The grinding teeth 34 on the outside of the third grinding disc 33 continuously squeeze the material so that the material is ground and crushed. Since the grinding teeth 34 are inclined, the material has a force of being squeezed obliquely downward under the action of rotation, which is more conducive to crushing. When the motor 4 drives the grinding roller 3 to rotate clockwise, the slope between the grinding teeth 34 and the outer walls of the first grinding disc 31, the second grinding disc 32 and the third grinding disc 33, and the inclined grinding teeth 34 will drive the material to move upward, so that the material in the third grinding cylinder 23 can fall into the second grinding cylinder 22, and the material in the second grinding cylinder 22 can fall into the first grinding cylinder 21. The material in the first grinding cylinder 21 enters the collecting tank 241 and finally flows out from the discharge pipe 242.

[0027] like Figure 5 As shown, the bottom of the third grinding cylinder 23 is fixedly connected with a second retaining ring 231, a gap is provided between the second retaining ring 231 and the second grinding cylinder 22, the outer lower part of the second retaining ring 231 is fixedly connected to the second grinding cylinder 22 through a fixing piece, the bottom of the second grinding cylinder 22 is fixedly connected with a first retaining ring 221, a gap is provided between the first retaining ring 221 and the first grinding cylinder 21, the outer lower part of the first retaining ring 221 is fixedly connected to the first grinding cylinder 21 through a fixing piece, and the bottom of the first grinding cylinder 21 is fixedly connected to the collecting plate 24.

[0028] An inclined collecting groove 241 is provided inside the collecting plate 24, and a discharge pipe 242 is provided outside the collecting plate 24, and one end of the discharge pipe 242 is connected to the collecting groove 241, and the other end of the discharge pipe 242 extends to the outside of the outer shell 1; a dividing plate 35 is also provided on the top of the third grinding cylinder 23, and a gap is provided between the dividing plate 35 and the third grinding cylinder 23, and the dividing plate 35 is fixedly connected to the third grinding cylinder 23 through a fixing part, and the dividing plate 35 and the third grinding plate 33 are not fixed.

[0029] like Figure 5 As shown, a driving rod 41 is fixedly connected to the output end of the motor 4, the top of the driving rod 41 is fixedly connected to the middle of the bottom of the first grinding disc 31, and an external thread 42 is provided on the outside of the driving rod 41, and the external thread 42 is a threaded shape protruding outward.

[0030] like Figure 7 As shown, the linkage mechanism 5 includes a movable frame 51, which is L-shaped. The movable frame 51 is provided with two groups. A threaded seat 52 is provided at the connection between the two groups of movable frames 51. The threaded seat 52 is installed on the outside of the driving rod 41, and the threaded seat 52 corresponds to the driving rod 41. A compression spring 53 is installed between the bottom of the movable frame 51 and the inner wall of the bottom of the shell 1. A connecting frame 54 is fixedly installed on the inner side of the top of the movable frame 51. When the threaded seat 52 is located above the external thread 42, under the action of the deadweight of the linkage mechanism 5, the driving rod 41 rotates counterclockwise, and the threaded seat 52 descends until the threaded seat 52 is disengaged from the external thread 42. The threaded seat 52 can slide on the outside of the driving rod 41, and the driving rod 41 rotates clockwise. The threaded seat 52 engages with the external thread 42 under the action of the compression spring 53, and the threaded seat 52 rises.

[0031] like Figure 7-Figure 8 As shown, the discharge control mechanism 6 includes a first baffle ring 61, a second baffle ring 62 and a third baffle ring 63 which are arranged in sequence from the inside to the outside, wherein the bottoms of the first baffle ring 61, the second baffle ring 62 and the third baffle ring 63 are respectively the tops of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23, the connecting frame 54 is fixedly connected to the first baffle ring 61, the second baffle ring 62 and the third baffle ring 63 through a slider 55, the first baffle ring 61, the second baffle ring 62 and the third baffle ring 63 are slidably connected to the lower part of the inner part of the positioning plate 7, the top of the positioning plate 7 is provided with a feed pipe 71 extending to the outside of the outer shell 1, and the middle part of the positioning plate 7 is provided with a groove which passes through from top to bottom.

[0032] The material discharging control mechanism 6 also includes a first material stop ring 64 and a second material stop ring 65 slidably connected under the positioning plate 7, wherein the first material stop ring 64 and the second material stop ring 65 are respectively located on the inner sides of the first stop ring 61 and the second stop ring 62, and correspond to the outer walls of the first stop ring 221 and the second stop ring 231.

[0033] A transmission mechanism 66 is provided between the first baffle ring 61 and the first baffle ring 64 and between the second baffle ring 62 and the second baffle ring 65. When the motor 4 drives the driving rod 41 to rotate counterclockwise, under the meshing action of the threaded seat 52 and the external thread 42, the movable frame 51 descends, and drives the first baffle ring 61, the second baffle ring 62 and the third baffle ring 63 to descend through the connecting frame 54 and the slider 55, and the first baffle ring 64 and the second baffle ring 65 to rise. At this time, the internal materials of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23 are ground under the counterclockwise rotation of the grinding roller 3. When the material is ground, the motor 4 drives the driving rod 41 to rotate clockwise, the movable frame 51 rises, the first baffle ring 61, the second baffle ring 62 and the third baffle ring 63 rise, and the first baffle ring 64 and the second baffle ring 65 rise. The baffle ring 65 descends, and the material overflows from the top of the first grinding cylinder 21, the second grinding cylinder 22 and the third grinding cylinder 23. The material overflowing from the first grinding cylinder 21 remains between the outer wall of the first grinding cylinder 21 and the inner wall of the second baffle ring 65, and the material overflowing from the second grinding cylinder 22 remains between the outer wall of the second grinding cylinder 22 and the inner wall of the first baffle ring 64. The material overflowing from the third grinding cylinder 23 enters the collecting trough 241 and is discharged from the discharge pipe 242. When the motor 4 is converted to counterclockwise rotation, the first baffle ring 61, the second baffle ring 62 and the third baffle ring 63 descend, and the first baffle ring 64 and the second baffle ring 65 rise. The material ground by the first grinding cylinder 21 enters the second grinding cylinder 22, and the material ground by the second grinding cylinder 22 enters the third grinding cylinder 23.

[0034] The transmission mechanism 66 includes a second tooth groove 662 arranged on the inner walls of the first retaining ring 61 and the second retaining ring 62, a spur gear 663 arranged on the outer walls of the first retaining ring 64 and the second retaining ring 65, and also includes a first tooth groove 661 installed below the positioning plate 7 through a mounting frame, the first tooth groove 661 is meshingly connected between the second tooth groove 662 and the spur gear 663, that is, when the first retaining ring 61 and the second retaining ring 62 descend, the first tooth groove 661 meshes with the spur gear 663 and the second tooth groove 662 to drive the first retaining ring 64 and the second retaining ring 65 to rise, and when the first retaining ring 61 and the second retaining ring 62 are lifted or lowered, the first tooth groove 661 meshes with the spur gear 663 and the second tooth groove 662 to drive the first retaining ring 64 and the second retaining ring 65 to descend.

[0035] The material enters the device through the feed pipe 71 and falls on the material distribution plate 35 to be dispersed. At this time, the first retaining ring 61, the second retaining ring 62, and the third retaining ring 63 are in the initial lower position, and the first retaining ring 64 and the second retaining ring 65 are in the initial upper position, so that the material can first enter the third grinding cylinder 23 to prepare for grinding;

[0036] The motor 4 drives the grinding roller 3 to rotate counterclockwise, and the grinding teeth 34 continuously grind the materials in the third grinding cylinder 23 by virtue of the inclined design and the downward extrusion force generated by the rotation. When the materials are ground to the standard, the motor 4 rotates clockwise, and the threaded seat 52 meshes with the external thread 42 of the driving rod 41 under the action of the compression spring 53 and rises, and drives the first stop ring 61, the second stop ring 62, and the third stop ring 63 to rise to the upper position through the linkage mechanism 5, and at the same time, the first stop ring 64 and the second stop ring 65 are lowered to the lower position by the transmission mechanism 66, so that the materials in the third grinding cylinder 23 overflow to the space between the third stop ring 63 and the third grinding cylinder 23;

[0037] The motor 4 rotates counterclockwise again, the first baffle ring 61, the second baffle ring 62, and the third baffle ring 63 descend, the first baffle ring 64 and the second baffle ring 65 rise, and the material enters the second grinding cylinder 22 for grinding. During this period, new material can enter the third grinding cylinder 23. Subsequently, the motor 4 is controlled to turn to make the material of the second grinding cylinder 22 enter the first grinding cylinder 21 for grinding, and finally discharged from the discharge pipe 242 of the first grinding cylinder 21, realizing three cycles of grinding and achieving continuous operation of feeding and discharging.

[0038] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0039] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An energy-saving grinding device for ganciclovir crude product before impurity removal, comprising a housing (1) and an inner cylinder (2) arranged inside the housing (1), and also comprising a grinding roller (3) arranged inside the inner cylinder (2), characterized in that: The inner cylinder (2) comprises a third grinding cylinder (23), a second grinding cylinder (22), a first grinding cylinder (21) and a collecting plate (24) which are sequentially connected from top to bottom, and the diameters of the first grinding cylinder (21), the second grinding cylinder (22) and the third grinding cylinder (23) decrease in sequence upwards, and the grinding roller (3) comprises a first grinding plate (31), a second grinding plate (32) and a third grinding plate which are respectively rotatably connected to the inside of the first grinding cylinder (21), the second grinding cylinder (22) and the third grinding cylinder (23). The first grinding disc (31), the second grinding disc (32) and the third grinding disc (33) are fixedly connected, and the outer edges of the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33) are evenly distributed with grinding teeth (34), and the grinding teeth (34) are arranged in an inclined manner, and one side of the grinding teeth (34) is smoothly transitioned with the outer wall of the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33), and the other side of the grinding teeth (34) is connected to the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33). The outer walls of the grinding disc (32) and the third grinding disc (33) are provided with a slope, and gaps for grinding are formed between the first grinding disc (31), the second grinding disc (32) and the third grinding disc (33) and the inner walls of the first grinding cylinder (21), the second grinding cylinder (22) and the third grinding cylinder (23), and the gap between the third grinding disc (33) and the third grinding cylinder (23) is larger than the gap between the second grinding disc (32) and the second grinding cylinder (22), and the gap between the first grinding disc (31) and the first grinding cylinder (21). A motor (4) is arranged inside the shell (1) below the grinding roller (3), and the motor (4) is used to drive the grinding roller (3) to rotate in the forward and reverse directions. A linkage mechanism (5) is arranged inside the shell (1) outside the grinding roller (3), and a discharge control mechanism (6) and a positioning plate (7) are arranged inside the shell (1) above the grinding roller (3), wherein the linkage mechanism (5) and the discharge control mechanism (6) are used to control the grinding of materials from top to bottom, and the positioning plate (7) is used to position the discharge control mechanism (6).

2. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 1 is characterized in that: The bottom of the third grinding cylinder (23) is fixedly connected to a second retaining ring (231), a gap is provided between the second retaining ring (231) and the second grinding cylinder (22), the lower outer side of the second retaining ring (231) is fixedly connected to the second grinding cylinder (22) via a fixing member, the bottom of the second grinding cylinder (22) is fixedly connected to a first retaining ring (221), a gap is provided between the first retaining ring (221) and the first grinding cylinder (21), the lower outer side of the first retaining ring (221) is fixedly connected to the first grinding cylinder (21) via a fixing member, and the bottom of the first grinding cylinder (21) is fixedly connected to a collecting plate (24).

3. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 1 is characterized in that: An inclined collecting groove (241) is provided inside the collecting plate (24), and a discharge pipe (242) is provided outside the collecting plate (24), one end of the discharge pipe (242) is connected to the collecting groove (241), and the other end of the discharge pipe (242) extends to the outside of the outer shell (1).

4. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 1 is characterized in that: A material distribution plate (35) is also provided on the top of the third grinding cylinder (23), a gap is provided between the material distribution plate (35) and the third grinding cylinder (23), the material distribution plate (35) is fixedly connected to the third grinding cylinder (23) via a fixing piece, and the material distribution plate (35) and the third grinding plate (33) are not fixed.

5. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 1 is characterized in that: The output end of the motor (4) is fixedly connected to a driving rod (41), the top of the driving rod (41) is fixedly connected to the middle of the bottom of the first grinding disc (31), and the outside of the driving rod (41) is provided with an external thread (42), and the external thread (42) is in the shape of a thread protruding outward.

6. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 5, characterized in that: The linkage mechanism (5) comprises a movable frame (51), the movable frame (51) is L-shaped, and the movable frame (51) is provided with two groups. A threaded seat (52) is provided at the connection between the two groups of movable frames (51), the threaded seat (52) is installed outside the driving rod (41), and the threaded seat (52) corresponds to the driving rod (41), a compression spring (53) is installed between the bottom of the movable frame (51) and the inner wall of the bottom of the shell (1), and a connecting frame (54) is fixedly installed on the inner side of the top of the movable frame (51).

7. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 6 is characterized in that: The discharging control mechanism (6) comprises a first baffle ring (61), a second baffle ring (62) and a third baffle ring (63) which are arranged in sequence from the inside to the outside, wherein the bottoms of the first baffle ring (61), the second baffle ring (62) and the third baffle ring (63) are respectively the tops of the first grinding cylinder (21), the second grinding cylinder (22) and the third grinding cylinder (23), the connecting frame (54) is fixedly connected to the first baffle ring (61), the second baffle ring (62) and the third baffle ring (63) through a slider (55), the first baffle ring (61), the second baffle ring (62) and the third baffle ring (63) are slidably connected to the inner bottom of the positioning plate (7), the top of the positioning plate (7) is provided with a feeding pipe (71) extending to the outside of the housing (1), and the middle of the positioning plate (7) is provided with a groove penetrating from top to bottom.

8. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 7, characterized in that: The material discharging control mechanism (6) further comprises a first material stop ring (64) and a second material stop ring (65) slidably connected below the positioning plate (7), wherein the first material stop ring (64) and the second material stop ring (65) are respectively located on the inner sides of the first stop ring (61) and the second stop ring (62), and correspond to the outer walls of the first stop ring (221) and the second stop ring (231).

9. The energy-saving grinding device for ganciclovir crude product before impurity removal as claimed in claim 8, characterized in that: A transmission mechanism (66) is provided between the first retaining ring (61) and the first material retaining ring (64), and between the second retaining ring (62) and the second material retaining ring (65).

10. The energy-saving grinding device for ganciclovir crude product before impurity removal according to claim 9, characterized in that: The transmission mechanism (66) comprises a second tooth groove (662) arranged on the inner wall of the first retaining ring (61) and the second retaining ring (62), a spur gear (663) arranged on the outer wall of the first retaining ring (64) and the second retaining ring (65), and also comprises a first tooth groove (661) installed below the positioning plate (7) through a mounting frame, and the first tooth groove (661) is meshingly connected between the second tooth groove (662) and the spur gear (663).

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