Traditional Chinese medicine compound shampoo and preparation method thereof

Abstract

The invention discloses traditional Chinese medicine compound shampoo and a preparation method thereof. Comprising the following components in parts by weight: 30-50 parts of a traditional Chinese medicine extract, 20-30 parts of a surfactant, 10-20 parts of a softening agent, 10-20 parts of a conditioner, 3-10 parts of essence, 1-3 parts of a preservative and 100-200 parts of water. According to the traditional Chinese medicine compound shampoo disclosed by the invention, a formula combining traditional Chinese medicine components and chemical components is adopted, so that the effects of removing dandruff and relieving itching are achieved on the basis of softening hair; in the components, the combined use of the piper wallichii extract and the cacumen biotae extract has the effect of removing dandruff, the combined use of the indigo naturalis extract and the drymoglossum piloselloides extract has the effect of relieving itching, the combined use of the alkylamidopropyl dimethylamine and the guar hydroxypropyltrimethylammonium chloride has the effect of improving combability, and the alkylamidopropyl dimethylamine and the guar hydroxypropyltrimethylammonium chloride have synergistic interaction.

Description

Technical Field

[0001] The invention belongs to the technical field of bathing products, and particularly relates to a Chinese medicine compound shampoo and a preparation method thereof. Background Art

[0002] Shampoo is a widely used personal care product, mainly used to clean the grease, sweat, exfoliated cells and foreign pollutants on the scalp and hair, keeping the scalp and hair clean and beautiful. The main ingredients of shampoo include surfactants, conditioners, active ingredients and additives. Surfactants are the core ingredients of shampoo, responsible for cleaning the hair and scalp, while avoiding excessive cleaning that causes the loss of natural oils. Conditioners give hair softness, gloss and anti-static properties. In addition, shampoo may also contain other ingredients such as pigments, fragrances, moisturizers, etc. to enhance the product experience.

[0003] Many shampoos contain chemical ingredients that are harmful to health, such as silicone oil, sulfates, parabens, formaldehyde-releasing substances, phthalates, etc. These ingredients may cause skin irritation, allergic reactions, hair loss, hormone imbalance and other problems. Long-term use of shampoos containing silicone oil or other harmful ingredients may cause clogged pores, dry hair, hair loss and other problems. Silicone oil is particularly difficult to wash off and easily remains on the scalp. Long-term accumulation may cause serious scalp problems.

[0004] Dandruff is a common problem that affects about 50% of adults worldwide, and it is more common in men than women. Dandruff generally refers to the appearance of flaky scales on the scalp or in the hair, and is often accompanied by itching. Currently, the academic community believes that there are three main factors that determine the formation of dandruff: Malassezia proliferation, scalp lipid secretion, and individual susceptibility. These three factors are interrelated and determine the time and form of dandruff. Current shampoos cannot completely solve the problem of dandruff and itching on the scalp. Summary of the invention

[0005] The purpose of the present invention is to provide a Chinese medicine compound shampoo and a preparation method thereof.

[0006] A traditional Chinese medicine compound shampoo comprises the following components in parts by weight: 30-50 parts of traditional Chinese medicine extract, 20-30 parts of surfactant, 10-20 parts of softener, 10-20 parts of conditioner, 3-10 parts of essence, 1-3 parts of preservative and 100-200 parts of water.

[0007] The Chinese medicinal extracts are heather vine extract, arborvitae leaf extract, indigo naturalis extract and scutellaria baicalensis extract.

[0008] The extraction method of the heather vine extract is as follows: taking the stems and leaves of heather vine, crushing them, adding 6-10 times the weight of water of heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.7-1.0 g / mL to obtain the heather vine extract.

[0009] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 8-12 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.7-1.0 g / mL to obtain the Platycladus orientalis leaf extract.

[0010] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 80-120 mesh sieve, adding water in an amount of 5-8 times the weight of indigo naturalis, refluxing and extracting them 1-3 times, combining the filtrates, filtering them with activated carbon, and concentrating the filtrate to 0.8-1.0 g / mL to obtain the indigo naturalis extract.

[0011] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 80-100 mesh sieve, adding water in an amount of 6-10 times the weight of Indigo naturalis, refluxing and extracting them 1-3 times, combining the filtrates, filtering them with activated carbon, and concentrating the filtrate to 0.7-0.9 g / mL to obtain the scutellaria baicalensis extract.

[0012] The surfactant is one or more of sodium laureth sulfate, laureth-2, sodium dodecyl sulfate, coconut oil monoethanolamide, and cocamidopropyl betaine.

[0013] The softener is one or more of polydimethylsiloxane, amino-terminated polydimethylsiloxane, polyquaternium-22, and polyquaternium-37.

[0014] The conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0015] The essence is one or more of jasmine essence, orchid essence, mint essence, rose essence, lavender essence, violet essence, and basil essence.

[0016] The preservative is one or more of ethylhexylglycerin, caprylyl glycol, p-hydroxyacetophenone, chlorphenesin, and phenoxyethanol.

[0017] The preparation method of the Chinese medicine compound shampoo is carried out according to the following steps: adding 20-30 parts of surfactant, 10-20 parts of softener and 10-20 parts of conditioner into 100-200 parts of water at 50-80°C, stirring evenly, cooling to room temperature (25°C), adding 30-50 parts of Chinese medicine extract, 3-10 parts of essence and 1-3 parts of preservative, and stirring evenly.

[0018] The beneficial effects of the invention are as follows: the Chinese medicine compound shampoo of the invention adopts a formula combining Chinese medicine components and chemical components, and achieves the effects of removing dandruff and relieving itching on the basis of softening hair; the combined use of the heather vine extract and the Platycladus orientalis leaf extract in the components has the effect of removing dandruff, the combined use of the Indigo naturalis extract and the Schefflera schefflera extract has the effect of relieving itching, and the combined use of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride has the effect of improving combing properties, and all of them synergistically enhance the effect. DETAILED DESCRIPTION

[0019] In order to facilitate the understanding of the present invention, the present invention will be described more fully below. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure of the present invention more thorough and comprehensive.

[0020] Example 1 A traditional Chinese medicine compound shampoo comprises the following components in parts by weight: 40 parts of traditional Chinese medicine extracts, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane, 15 parts of conditioning agents, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of caprylyl glycol, and 150 parts of water; the traditional Chinese medicine extracts are heather vine extract, arborvitae leaf extract, indigo naturalis extract, and scutellaria baicalensis extract; the dosage mass ratio is 2:1:1:3; the conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0021] The extraction method of the heather vine extract is as follows: taking stems and leaves of the heather vine, crushing them, adding water 8 times the weight of the heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.9 g / mL to obtain the heather vine extract.

[0022] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 10 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.85 g / mL to obtain the Platycladus orientalis leaf extract.

[0023] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 100-mesh sieve, adding water in an amount of 6 times the weight of indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.9 g / mL to obtain the indigo naturalis extract.

[0024] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 90-mesh sieve, adding water in an amount of 8 times the weight of Indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.8 g / mL to obtain the scutellaria baicalensis extract.

[0025] The preparation method of the Chinese medicine compound shampoo is carried out according to the following steps: at 65°C, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane and 15 parts of a conditioning agent are added to 150 parts of water, stirred evenly, cooled to room temperature (25°C), 40 parts of Chinese medicine extract, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of caprylyl glycol are added, and stirred evenly.

[0026] Example 2 A traditional Chinese medicine compound shampoo comprises the following components in parts by weight: 30 parts of traditional Chinese medicine extracts, 20 parts of sodium lauryl sulfate, 10 parts of polyquaternium-22, 10 parts of a conditioning agent, 4 parts of mint essence, 0.5 parts of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of p-hydroxyacetophenone, and 100 parts of water; the traditional Chinese medicine extracts are heather vine extract, arborvitae leaf extract, indigo naturalis extract, and scutellaria baicalensis extract, and the mass ratio of the extracts is 1:1:1:2; the conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0027] The extraction method of the heather vine extract is as follows: taking stems and leaves of heather vine, crushing them, adding water 6 times the weight of heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.75 g / mL to obtain the heather vine extract.

[0028] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 8 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.8 g / mL to obtain the Platycladus orientalis leaf extract.

[0029] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through an 80-mesh sieve, adding water in an amount of 5 times the weight of indigo naturalis, refluxing and extracting them once, filtering with activated carbon, concentrating the filtrate to 0.85 g / mL, and obtaining the indigo naturalis extract.

[0030] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through an 80-mesh sieve, adding water in an amount of 6 times the weight of Indigo naturalis, refluxing and extracting them once, filtering with activated carbon, concentrating the filtrate to 0.75 g / mL, and obtaining the scutellaria baicalensis extract.

[0031] The preparation method of the traditional Chinese medicine compound shampoo is carried out according to the following steps: at 55° C., 20 parts of sodium lauryl sulfate, 10 parts of polyquaternium-22 and 10 parts of a conditioning agent are added into 100 parts of water, stirred evenly, cooled to room temperature (25° C.), 30 parts of traditional Chinese medicine extract, 4 parts of mint essence, 0.5 parts of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of p-hydroxyacetophenone are added, and stirred evenly.

[0032] Example 3 A traditional Chinese medicine compound shampoo comprises the following components in parts by weight: 50 parts of traditional Chinese medicine extracts, 30 parts of cocamidopropyl betaine, 20 parts of polyquaternium-37, 20 parts of a conditioning agent, 8 parts of violet essence, 1 part of phenoxyethanol, 1 part of caprylyl glycol, 1 part of chlorphenesin, and 200 parts of water; the traditional Chinese medicine extracts are heather vine extract, arborvitae leaf extract, indigo naturalis extract, and scutellaria baicalensis extract, and the usage mass ratio is 3:1:1:4; the conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0033] The extraction method of the heather vine extract is as follows: taking the stems and leaves of heather vine, crushing them, adding water 10 times the weight of heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.95 g / mL to obtain the heather vine extract.

[0034] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 12 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.9 g / mL to obtain the Platycladus orientalis leaf extract.

[0035] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 120-mesh sieve, adding water in an amount of 8 times the weight of indigo naturalis, refluxing and extracting them 3 times, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.95 g / mL to obtain the indigo naturalis extract.

[0036] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 100-mesh sieve, adding water in an amount 10 times the weight of Indigo naturalis, refluxing and extracting them three times, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.85 g / mL to obtain the scutellaria baicalensis extract.

[0037] The preparation method of the traditional Chinese medicine compound shampoo is carried out according to the following steps: at 75° C., 30 parts of cocamidopropyl betaine, 20 parts of polyquaternium-37 and 20 parts of a conditioning agent are added into 200 parts of water, stirred evenly, cooled to room temperature (25° C.), 50 parts of a traditional Chinese medicine extract, 8 parts of violet essence, 1 part of phenoxyethanol, 1 part of caprylyl glycol and 1 part of chlorphenesin are added, and stirred evenly.

[0038] Comparative Example 1 A Chinese medicine compound shampoo comprises the following components in parts by weight: 40 parts of Chinese medicine extracts, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane, 15 parts of conditioning agents, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of caprylyl glycol, and 150 parts of water; the Chinese medicine extracts are heather vine extract, indigo naturalis extract, and scutellaria baicalensis extract; the dosage mass ratio is 3:1:3; the conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0039] The extraction method of the heather vine extract is as follows: taking stems and leaves of the heather vine, crushing them, adding water 8 times the weight of the heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.9 g / mL to obtain the heather vine extract.

[0040] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 100-mesh sieve, adding water in an amount of 6 times the weight of indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.9 g / mL to obtain the indigo naturalis extract.

[0041] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 90-mesh sieve, adding water in an amount of 8 times the weight of Indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.8 g / mL to obtain the scutellaria baicalensis extract.

[0042] The preparation method of the Chinese medicine compound shampoo is carried out according to the following steps: at 65°C, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane and 15 parts of a conditioning agent are added to 150 parts of water, stirred evenly, cooled to room temperature (25°C), 40 parts of Chinese medicine extract, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of caprylyl glycol are added, and stirred evenly.

[0043] Comparative Example 2 A Chinese medicine compound shampoo comprises the following components in parts by weight: 40 parts of Chinese medicine extract, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane, 15 parts of a conditioning agent, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of caprylyl glycol, and 150 parts of water; the Chinese medicine extract is Platycladus orientalis leaf extract, Indigo naturalis extract, and Scutellaria baicalensis extract; the dosage mass ratio is 3:1:3; the conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0044] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 10 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.85 g / mL to obtain the Platycladus orientalis leaf extract.

[0045] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 100-mesh sieve, adding water in an amount of 6 times the weight of indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.9 g / mL to obtain the indigo naturalis extract.

[0046] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 90-mesh sieve, adding water in an amount of 8 times the weight of Indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.8 g / mL to obtain the scutellaria baicalensis extract.

[0047] The preparation method of the Chinese medicine compound shampoo is carried out according to the following steps: at 65°C, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane and 15 parts of a conditioning agent are added to 150 parts of water, stirred evenly, cooled to room temperature (25°C), 40 parts of Chinese medicine extract, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of caprylyl glycol are added, and stirred evenly.

[0048] Comparative Example 3 A Chinese medicine compound shampoo comprises the following components in parts by weight: 40 parts of Chinese medicine extracts, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane, 15 parts of conditioning agents, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of caprylyl glycol, and 150 parts of water; the Chinese medicine extracts are heather vine extract, arborvitae leaf extract, and indigo naturalis extract; the dosage mass ratio is 2:1:4; the conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0049] The extraction method of the heather vine extract is as follows: taking stems and leaves of the heather vine, crushing them, adding water 8 times the weight of the heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.9 g / mL to obtain the heather vine extract.

[0050] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 10 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.85 g / mL to obtain the Platycladus orientalis leaf extract.

[0051] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 100-mesh sieve, adding water in an amount of 6 times the weight of indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.9 g / mL to obtain the indigo naturalis extract.

[0052] The preparation method of the Chinese medicine compound shampoo is carried out according to the following steps: at 65°C, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane and 15 parts of a conditioning agent are added to 150 parts of water, stirred evenly, cooled to room temperature (25°C), 40 parts of Chinese medicine extract, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of caprylyl glycol are added, and stirred evenly.

[0053] Comparative Example 4 A Chinese medicine compound shampoo comprises the following components in parts by weight: 40 parts of Chinese medicine extract, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane, 15 parts of a conditioning agent, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of caprylyl glycol, and 150 parts of water; the Chinese medicine extract is heather vine extract, Platycladus orientalis leaf extract, and scutellaria baicalensis extract; the dosage mass ratio is 2:1:4; the conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:1.

[0054] The extraction method of the heather vine extract is as follows: taking stems and leaves of the heather vine, crushing them, adding water 8 times the weight of the heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.9 g / mL to obtain the heather vine extract.

[0055] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 10 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.85 g / mL to obtain the Platycladus orientalis leaf extract.

[0056] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 90-mesh sieve, adding water in an amount of 8 times the weight of Indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.8 g / mL to obtain the scutellaria baicalensis extract.

[0057] The preparation method of the Chinese medicine compound shampoo is carried out according to the following steps: at 65°C, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane and 15 parts of a conditioning agent are added to 150 parts of water, stirred evenly, cooled to room temperature (25°C), 40 parts of Chinese medicine extract, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of caprylyl glycol are added, and stirred evenly.

[0058] Comparative Example 5 A traditional Chinese medicine compound shampoo comprises the following components in parts by weight: 40 parts of traditional Chinese medicine extracts, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane, 15 parts of alkylamidopropyl dimethylamine, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of caprylyl glycol, and 150 parts of water; the traditional Chinese medicine extracts are heather vine extract, arborvitae leaf extract, indigo naturalis extract, and scutellaria baicalensis extract; and the dosage mass ratio is 2:1:1:3.

[0059] The extraction method of the heather vine extract is as follows: taking stems and leaves of the heather vine, crushing them, adding water 8 times the weight of the heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.9 g / mL to obtain the heather vine extract.

[0060] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 10 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.85 g / mL to obtain the Platycladus orientalis leaf extract.

[0061] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 100-mesh sieve, adding water in an amount of 6 times the weight of indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.9 g / mL to obtain the indigo naturalis extract.

[0062] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 90-mesh sieve, adding water in an amount of 8 times the weight of Indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.8 g / mL to obtain the scutellaria baicalensis extract.

[0063] The preparation method of the traditional Chinese medicine compound shampoo is carried out according to the following steps: at 65°C, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane and 15 parts of alkylamidopropyl dimethylamine are added to 150 parts of water, stirred evenly, cooled to room temperature (25°C), 40 parts of traditional Chinese medicine extract, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of caprylyl glycol are added, and stirred evenly.

[0064] Comparative Example 6 A traditional Chinese medicine compound shampoo comprises the following components in parts by weight: 40 parts of traditional Chinese medicine extracts, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane, 15 parts of guar hydroxypropyltrimethylammonium chloride, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin, 0.5 parts of caprylyl glycol, and 150 parts of water; the traditional Chinese medicine extracts are heather vine extract, arborvitae leaf extract, indigo naturalis extract, and scutellaria baicalensis extract; and the dosage mass ratio is 2:1:1:3.

[0065] The extraction method of the heather vine extract is as follows: taking stems and leaves of the heather vine, crushing them, adding water 8 times the weight of the heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.9 g / mL to obtain the heather vine extract.

[0066] The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 10 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.85 g / mL to obtain the Platycladus orientalis leaf extract.

[0067] The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 100-mesh sieve, adding water in an amount of 6 times the weight of indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.9 g / mL to obtain the indigo naturalis extract.

[0068] The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 90-mesh sieve, adding water in an amount of 8 times the weight of Indigo naturalis, refluxing and extracting them twice, combining the filtrates, filtering with activated carbon, and concentrating the filtrate to 0.8 g / mL to obtain the scutellaria baicalensis extract.

[0069] The preparation method of the traditional Chinese medicine compound shampoo is carried out according to the following steps: at 65°C, 25 parts of sodium laureth sulfate, 15 parts of polydimethylsiloxane and 15 parts of guar hydroxypropyltrimethylammonium chloride are added to 150 parts of water, stirred evenly, cooled to room temperature (25°C), 40 parts of traditional Chinese medicine extract, 6 parts of jasmine essence, 1 part of phenoxyethanol, 0.5 parts of ethylhexylglycerin and 0.5 parts of caprylyl glycol are added, and stirred evenly.

[0070] Experimental Example 1: Ketoconazole powder was diluted to 0.2 mg / mL with mDixon medium. The extract of Heather striata and Platycladus orientalis leaves prepared in Example 1 were diluted 5 times with distilled water and set aside.

[0071] To prepare the culture medium, add 66 g mDixon culture medium powder, 10 g Tween 40, and 1.5 g agar powder to 1 L of water, sterilize under high pressure at 121°C for 15 min, cool to 50°C and pour into a plate. After solidification, place in a 4°C refrigerator for later use.

[0072] The test strain is Malassezia furfur (M. furfur, ATCC 44344), which is purchased as a freeze-dried powder in an ampoule tube. Heat the tip of the ampoule tube over a flame, drip sterile water onto the heated area to break it, knock off the top of the ampoule tube with tweezers, and pass the opening over the flame once, use a sterile pipette to draw 1 mL of sterile saline, drip it into the tube, wait for the powder to dissolve and become suspended, use a sterile pipette to draw the bacterial solution onto a sterile plate, and culture at 32°C for 3 days before subculturing. After two subculturings, pick the colony with an inoculation loop in sterile saline, blow and aspirate several times, adjust its turbidity to McFarland No. 1 turbidimetric tube, spread the plate and count its concentration to 3×10 6 CFU / mL. Dilute the bacterial suspension 10 times with sterile saline, take 100μL and evenly spread on the plate, and dry. Place 2 Oxford cups evenly on each plate, add 200μL of drug solution to each Oxford cup, set up 3 parallels for each drug, and set up a 0.2mg / mL ketoconazole positive control. Incubate at 32℃ for 72 h in an incubator, take pictures, and measure the diameter of the inhibition zone with Image J. Measure each cup 3 times and take the average value.

[0073] The experimental results were statistically analyzed using SPSS 24.0 software. The measurement data were expressed as x±(mean±standard deviation). The Kolmogorov-Smirnov test was used for data normality test. For data that met the normal distribution, the t-test was used to compare the mean differences between the two groups. P<0.05 was considered statistically significant. The measurement results are shown in Table 1: Table 1

[0074] Note: * represents P < 0.05 compared with the group of "100 μL of Heather vine extract + 100 μL of Platycladus orientalis leaf extract".

[0075] Experimental Example 2: C57BL / 6 adult mice of the same size were selected and randomly divided into Example 1-3 groups, Comparative Example 1-4 groups, and a model blank group, a total of 8 groups, 10 mice in each group; 2 days before the experiment, the back of the mice was shaved, and the shaved area was 3 cm×3 cm. On the day of the experiment, the corresponding shampoo was evenly applied to the shaved area of ​​each group of mice, and deionized water was evenly applied to the shaved area of ​​the mice in the model blank group, and the application amount for each mouse was 1 mL; 30 minutes after the application, 1.5 mg / kg of 4-aminopyridine was subcutaneously injected at the shaved area, and the number of licking reactions of each group of animals within 20 minutes after the injection of 4-aminopyridine was recorded (average per animal).

[0076] The experimental results were statistically analyzed using SPSS 24.0 software. The measurement data were expressed as x±(mean±standard deviation). The Kolmogorov-Smirnov test was used for data normality test. For data that met the normal distribution, the t-test was used to compare the mean differences between the two groups. P<0.05 was considered statistically significant. The measurement results are shown in Table 2: Table 2

[0077] Note: * represents P < 0.05 compared with the group in Example 1.

[0078] Experimental Example 3: The shampoos prepared in Examples 1-3 of the present invention and Comparative Examples 5-6 were subjected to performance tests. The wet hair combing property was measured using a tensile tester. The shampoos were considered stable if they were left standing for 3 months at 45°C without stratification. The experimental results were statistically analyzed using SPSS 24.0 software. The quantitative data results were expressed as x±(mean±standard deviation). The Kolmogorov-Smirnov test method was used for data normality test. For data that met the normal distribution, the mean difference between the two groups was compared using a t-test. The difference was considered statistically significant when P<0.05. The test results are shown in Table 3: Table 3

[0079] Note: * represents P < 0.05 compared with Example 1 group The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A Chinese medicine compound shampoo, characterized in that: The invention comprises the following components in parts by weight: 30-50 parts of Chinese herbal medicine extract, 20-30 parts of surfactant, 10-20 parts of softener, 10-20 parts of conditioner, 3-10 parts of essence, 1-3 parts of preservative and 100-200 parts of water.

2. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The Chinese medicinal extracts are heather vine extract, arborvitae leaf extract, indigo naturalis extract and spatholobi extract.

3. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The extraction method of the heather vine extract is as follows: taking the stems and leaves of heather vine, crushing them, adding 6-10 times the weight of water of heather vine, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.7-1.0 g / mL to obtain the heather vine extract.

4. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The extraction method of the Platycladus orientalis leaf extract is as follows: taking Platycladus orientalis leaves, crushing them, adding water 8-12 times the weight of the Platycladus orientalis leaves, performing microwave extraction, filtering to obtain a filtrate, and concentrating the filtrate to 0.7-1.0 g / mL to obtain the Platycladus orientalis leaf extract.

5. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The extraction method of the indigo naturalis extract is as follows: taking the stems and leaves of indigo naturalis, drying them in the sun, crushing them, passing them through a 80-120 mesh sieve, adding water in an amount of 5-8 times the weight of indigo naturalis, refluxing and extracting them 1-3 times, combining the filtrates, filtering them with activated carbon, and concentrating the filtrate to 0.8-1.0 g / mL to obtain the indigo naturalis extract.

6. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The extraction method of the scutellaria baicalensis extract is as follows: taking the stems and leaves of the scutellaria baicalensis, drying them in the sun, crushing them, passing them through a 80-100 mesh sieve, adding water in an amount of 6-10 times the weight of Indigo naturalis, refluxing and extracting them 1-3 times, combining the filtrates, filtering them with activated carbon, and concentrating the filtrate to 0.7-0.9 g / mL to obtain the scutellaria baicalensis extract.

7. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The surfactant is one or more of sodium laureth sulfate, laureth-2, sodium dodecyl sulfate, coconut oil monoethanolamide, and cocamidopropyl betaine; the softener is one or more of polydimethylsiloxane, amino-terminated polydimethylsiloxane, polyquaternium-22, and polyquaternium-37.

8. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The conditioning agent is a mixture of alkylamidopropyl dimethylamine and guar hydroxypropyltrimethylammonium chloride in a mass ratio of 2:

1.

9. The Chinese medicinal compound shampoo according to claim 1, characterized in that: The essence is one or more of jasmine essence, orchid essence, mint essence, rose essence, lavender essence, violet essence, and basil essence; the preservative is one or more of ethylhexylglycerin, caprylyl glycol, p-hydroxyacetophenone, chlorphenesin, and phenoxyethanol.

10. The method for preparing the Chinese medicinal compound shampoo according to claim 1, characterized in that: Proceed as follows: at 50-80°C, add 20-30 parts of surfactant, 10-20 parts of softener, 10-20 parts of conditioner, 3-10 parts of flavor, and 1-3 parts of preservative to 100-200 parts of water, stir evenly, cool to room temperature, add 30-50 parts of Chinese herbal extract, and stir evenly.

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