Optimized formula containing ossein and casein phosphopeptides and combining glucosamine for increasing bone mineral density with traditional Chinese medicines of rhizoma drynariae and radix morindae officinalis
By using optimized formulas of components such as D-amino acid glucose potassium sulfate, the problems of bone density reduction and joint cartilage damage in osteoarthropathy are solved, and the effect of effectively improving bone density and repairing joint cartilage is achieved, providing a long-term Sustainable treatment options.
Patent Information
- Application Number
- CN202411016121.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-27
- Publication Date
- 2025-02-18
AI Technical Summary
The existing treatment methods for osteoarthropathy mainly rely on symptomatic drugs, which have side effects and cannot effectively solve the problems of reduced bone density and articular cartilage damage.
Optimized formulas of D-amino acid glucose potassium sulfate, bone granule extract, Morinaceae, casein phosphopeptide and calcium carbonate are used to promote chondrocyte regeneration, enhance bone density and improve joint function, providing a long-term solution by promoting chondrocyte regeneration, enhancing bone density and improving joint function. Continuous treatment options.
Effectively improve bone density, reduce the symptoms of respiratory and low back pain caused by osteoporosis, inhibit the activity of cartilage destruction enzymes, repair joint cartilage, restore normal physiological functions of joint parts, and have strong product stability, with a shelf life of more than 24 months .
Abstract
Description
Technical Field
[0001] The present invention relates to an optimized formula containing bone collagen and casein phosphopeptide, which is a combination of glucosamine for increasing bone density and traditional Chinese medicines Rhizoma Drynariae and Radix Morindae Officinalis. Background Art
[0002] Osteoarthritis, also known as degenerative osteoarthritis, abbreviated as OA, starts from the articular cartilage and affects the entire joint structure, including subchondral bone, ligaments, synovium, joint capsule and extra-articular muscles. It is a disease that eventually leads to joint deformity and loss of function due to partial or complete loss of articular cartilage. Osteoarthritis is the most common disease among the elderly. Patients suffer from pain and swelling every day. It is defined by the World Health Organization as the "number one disabling disease." The latest random sampling survey on the incidence of osteoarthritis in the knees, hips and hands of the elderly shows that the prevalence of osteoarthritis in the elderly over 55 years old is more than 50%, and the prevalence in people over 75 years old is about 80%; although osteoarthritis causes pain in the joints, the root cause is in the cartilage; the knee joint has a thin layer of cartilage, which is like a "lubricant" between bones. Without its protection, bones will rub against bones when walking, and it will be very painful because the periosteum is rich in nerves and blood vessels; cartilage is a dense gelatinous substance, which is not only strong, but also more elastic than bones; Current status of bone and joint treatment: patients are treated with some drugs to relieve symptoms, which mainly include analgesics and non-steroidal anti-inflammatory drugs. The basic pathological changes of osteoarthritis are not affected, but pain relief and symptom improvement can be achieved quickly. However, the side effects are large, gastrointestinal reactions, renal toxicity, blood changes, increased bleeding risk, etc. are prone to occur, and it is not suitable for long-term use. Since the etiology of osteoarthritis is complex and the course of disease is usually long, the long-term illness will inevitably lead to the decline of the body functions of these patients. Combined with the current situation of osteoarthritis in my country, the clinical medicine of osteoarthritis has put forward five major requirements for the development of new drugs for osteoarthritis: improving the condition of joint disease; enhancing bone protection; improving joint immunity; improving gastrointestinal absorption function; It has no effect on the treatment of other diseases, has no side effects, and can be taken for a long time; Bone and joint diseases are definitely difficult to deal with. After contracting, joints become swollen, painful, effused, stiff, hyperplastic, with bone spurs, and difficult to move. The most annoying thing is that they cannot be cured for a long time and are very likely to recur. Medical research shows that "the root of joint pain is cartilage." If the drugs used do not contain enough glucosamine, an effective ingredient that can repair cartilage, they will naturally not be able to fundamentally solve the problem of bone and joint diseases. Summary of the invention
[0003] The invention aims to adopt a scientific combination of D-amino acid glucose sulfate potassium salt, drynaria extract, Morinda officinalis, casein phosphopeptide and calcium carbonate according to a new reasonable scientific formula based on modern nutrition theory.
[0004] From the perspective of molecular structure, glucosamine sulfate is a sulfate radical, which has no side effects and can be taken before or after meals. From the perspective of safety, sulfate ions can be taken for a long time, and D-glucosamine sulfate potassium salt is a glucosamine sulfate that can also supplement potassium. It is an important participant in human protein synthesis and is a small molecule that is easily absorbed. D-amino acid glucose sulfate potassium salt repairs cartilage and enhances bone density. It can more efficiently and quickly promote glucosamine to repair cartilage, promote chondrocyte regeneration, promote collagen synthesis, and strengthen cartilage; it promotes blood fluidity and permeability, and cooperates with cartilage repair, anti-aging, and eyesight.
[0005] Collagen, also known as structural protein, accounts for 30%-40% of the total protein in the human body. It is an important component of human muscles and skin, and is very helpful in maintaining the toughness of bones, the coordination of human movements and the elasticity of the skin. Collagen prevents the loss of nutrients and locks in nutrients.
[0006] Drynaria fortunei is a traditional Chinese medicine that nourishes the kidney, promotes blood circulation and stops bleeding. It can treat chronic diarrhea due to kidney deficiency, low back pain, rheumatic arthralgia, toothache, tinnitus, bruises, sprains, bone injuries, etc. It can promote blood circulation, remove blood stasis, and relieve inflammation and pain.
[0007] Morinda officinalis is a traditional Chinese medicine that can nourish kidney yang, strengthen tendons and bones, and dispel rheumatism. It has the effects of improving immunity, increasing white blood cell levels, and dispelling rheumatism. Heng has the reputation of "Southern Ginseng" and can warm and nourish kidney yang, strengthen tendons and bones.
[0008] Casein phosphopeptide Casein phosphopeptide (CPP) is a biologically active polypeptide extracted from milk using bovine casein as raw material through biotechnology. It can be used in various nutritional foods and health foods. It can effectively promote the body's absorption and effective utilization of divalent mineral nutrients such as calcium, iron, and zinc, and promote the absorption of trace elements calcium, iron, zinc, and selenium in the human body.
[0009] Calcium, known as the element of life, is one of the most important essential elements for the human body. Calcium is not only the main nutrient for human bones and teeth, but also participates in many physiological functions of the human body. It plays a vital role in maintaining the functions of the immune system and neuromuscular system; it replenishes the element calcium lost by the human body.
[0010] In order to overcome the shortcomings and deficiencies of the existing glucosamine technology, such as the unsatisfactory effect of the single combination variety and the unreasonable combination, the purpose of the present invention is to provide an optimized formula of glucosamine for increasing bone density, which is combined with the traditional Chinese medicines Drynaria fortunei and Morinda officinalis and contains collagen and casein phosphopeptide.
[0011] The purpose of the present invention is achieved through the following technical solutions: An optimized formula of glucosamine for increasing bone density combined with Chinese medicines Rhizoma Drynariae and Morinda officinalis containing bone collagen and casein phosphopeptide comprises the following steps: Contents: D-amino acid glucose potassium sulfate, drynaria extract, Morinda officinalis, casein phosphopeptide, calcium carbonate; Preparation of the contents: weigh the raw materials of the contents according to the formula amount and mix them evenly to obtain the contents; The main steps of the powder granule preparation after uniform mixing are: mixing, drying, capsule filling, bottling and other main processes.
[0012] The invention discloses an optimized formula of glucosamine for increasing bone density, which is combined with Chinese medicines Rhizoma Drynariae and Morinda officinalis and contains bone collagen and casein phosphopeptide. Adults can take 3 capsules twice a day with warm water. The effective ingredients can stimulate chondrocytes to synthesize a large amount of human cartilage matrix, and can stimulate the human body to synthesize glucosamine and collagen to make up for the proteoglycan and collagen organic matter in the bone matrix that have been consumed and lost. Glucosamine can also inhibit the activity of bone-destroying and degrading enzymes, so that less is consumed and more is synthesized, and the bone matrix is gradually improved. Bone density can be effectively improved, osteoporosis can be resisted, respiratory and back pain symptoms caused by it can be eliminated, and the activity of cartilage-destroying enzymes can be inhibited to continuously repair articular cartilage that has been damaged by wear or inflammatory substances, thereby restoring the normal physiological function of the joint part. The product can be taken for a long time, and the shelf life is more than 24 months. The product has strong stability.
[0013] In addition, the present invention may also be implemented in other ways, and any obvious replacement without departing from the concept of the present invention is within the protection scope of the present invention.
[0014] Success Stories: Aunt Yan from Mudanjiang is 83 years old. She took the product home and took it for 3 days. She felt a little numbness and heat in her right leg, so she took another 3 boxes. Now she has taken it for 20 days. Before, she dared not lift her right leg when walking, and she walked slowly. Now both legs are the same, and she walks much more briskly. Aunt Luan is 81 years old. She dare not touch cold water with her hands. When she touches cold water, her finger joints feel like being pricked by needles, and her legs and feet also hurt. In her words, her whole body hurts. After taking it for 7 days, she is much better now and does not hurt as much as before. Aunt Wang from Yuxi is 80 years old. She used to walk unsteadily, suffer from leg pain and cramps, and her daughter was worried about her when she went out. She couldn’t stretch her fingers, especially couldn’t squat. Since taking the sixth-generation glucosamine, Aunt Wang’s walking has improved a lot, and her finger joints don’t hurt as much, especially she can squat. It’s amazing that an 80-year-old can squat and stand up continuously! Uncle Sheng Zhimin, 76 years old, had leg pain and cramps when walking, and felt weak after standing for a long time. He had many joint problems, which caused his physical condition to deteriorate day by day, and his eyes often shed tears when exposed to the wind. He took Glucosamine Collagen for two weeks and the effect was obvious. He took 6 capsules a day and could read the newspaper much more clearly. He walked more powerfully, his legs and feet became more flexible, and his hand joints were no longer so numb and swollen. Some joints feel hot and itchy; some joints feel less heavy; some joints feel more flexible than before; Some feel less soreness and pain now; some had joint pain before, but now the pain has improved significantly; some people with frozen shoulder have difficulty raising their arms and have experienced tingling pain, but now the pain has eased and the effect is better when used with blood circulation products; some feel that their joints are more painful than at the beginning, but after about 1-2 weeks, the pain has eased and gradually improved.
Claims
1. An optimized formula for increasing bone density, comprising glucosamine combined with the Chinese medicines Rhizoma Drynariae and Morinda officinalis, and containing collagen and casein phosphopeptide.
1.
2. According to claim 1, an optimized formula of glucosamine for increasing bone density combined with Chinese medicines Rhizoma Drynariae and Morinda officinalis containing collagen and casein phosphopeptide is obtained by weighing the raw materials according to the formula amount and mixing them evenly to obtain the powder granule preparation after mixing evenly, and the main steps are: mixing, drying, capsule filling, bottling and other main processes to prepare the preparation method 2.
3. The finished product of the optimized formula of glucosamine for increasing bone density according to claim 2, combined with the Chinese medicines Rhizoma Drynariae and Morinda Officinalis, containing collagen and casein phosphopeptide, is a hard capsule 3.
4. According to claims 1 and 2, an optimized formula of glucosamine for increasing bone density combined with the traditional Chinese medicines Rhizoma Drynariae and Morinda officinalis containing collagen and casein phosphopeptide comprises: D-amino acid glucose potassium sulfate, Rhizoma Drynariae extract, Morinda officinalis, casein phosphopeptide, and calcium carbonate 4.