Sticky sampling device for cast-off cells

Abstract

The invention discloses an exfoliated cell sticking and sampling device which comprises a sampler, the sampler comprises a shell, a conical tube and a storage tube, the conical tube is fixedly mounted at the bottom of the shell and communicated with the shell, the storage tube is fixedly mounted on the surface of the conical tube and communicated with the conical tube, and the storage tube is obliquely arranged. The invention aims to solve the technical problems that in the process of sampling cast-off cells by an existing cast-off cell sticking and sampling device, manual sticking is needed, so that the labor intensity of a user is high, the sticking efficiency is low, the situation that a sampling result cannot meet the requirement easily occurs, and a sticking structure is difficult to feed efficiently.

Description

Technical Field

[0001] The invention relates to the technical field of microbial sampling, in particular to a device for sampling exfoliated cells by adhesion. Background Art

[0002] In DNA detection, it is of great significance to detect microorganisms in exfoliated cells. Adhesive devices can help accurately collect exfoliated tissue samples, thereby improving the accuracy of experimental results. For the task of extracting exfoliated cells from large-area fabrics, the area that needs to be sampled is extremely large. Experimenters even need to hold the adhesive device and click it continuously for multiple times, which is a huge workload and time-consuming. In addition, since the strength and number of times of each sticking by the experimenter are different, it is impossible to ensure that the sampling results meet the requirements. The exfoliated cell adhesive device with Chinese patent application number 201420184135.3 has a structure including an adhesive roller and an operating handle for pushing the adhesive roller to roll. The adhesive roller includes a wheel body, a cushion layer attached to the outer circumference of the wheel body, and a composite adhesive surface layer wrapped on the outer circumference of the cushion layer. The composite adhesive surface layer is a layer of sterile double-sided adhesive layer with sterile inner protective film layer and outer protective film layer on the inner and outer sides respectively. The adhesive device adheres to the exfoliated cells through the adhesive surface layer.

[0003] In the process of sampling exfoliated cells, the existing exfoliated cell sticking sampling device needs to manually stick to the exfoliated cells, which leads to high labor intensity and low sticking efficiency for users. It is easy for the sampling results to fail to meet the requirements, and it is difficult to efficiently load the sticking structure. Summary of the invention

[0004] The technical problem to be solved by the present invention is that in the process of sampling exfoliated cells in the existing exfoliated cell adhesion sampling device, manual adhesion is required, which leads to high labor intensity for users and low adhesion efficiency, and it is easy for the sampling results to fail to meet the requirements, and it is difficult to efficiently load the adhesion structure.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: a device for collecting and sampling exfoliated cells, comprising a sampler, The sampler comprises a housing, a conical tube and a storage tube, wherein the conical tube is fixedly mounted on the bottom of the housing and communicated with the housing, the storage tube is fixedly mounted on the surface of the conical tube and communicated with the housing, and the storage tube is arranged obliquely; The inner cavity of the storage tube is provided with a plurality of sticking devices, and a material discharge assembly is rotatably connected to the conical tube. The material discharge assembly is movably connected to the sticking device and is used to control the falling of the sticking device. An annular proximity sensor is fixedly installed at the bottom of the shell, and the annular proximity sensor detects the falling sticking device.

[0006] As a preferred solution of the exfoliated cell adhesion sampling device of the present invention, wherein: a closing cover is threadedly connected to the top of the shell, a control module is fixedly installed inside the closing cover, and the control module is electrically connected to the annular proximity sensor.

[0007] As a preferred solution of the exfoliated cell adhesion sampling device of the present invention, a power supply system is fixedly installed in the inner cavity of the shell, a charging module electrically connected to the power supply system is fixedly installed on the power supply system, and the charging module penetrates the surface of the shell.

[0008] As a preferred embodiment of the exfoliated cell adhesion sampling device described in the present invention, the bottom of the inner cavity of the shell is fixedly connected to an iron core, the surface of the iron core is sleeved with an electromagnetic coil, a movable slide rod is movably connected inside the iron core, a limit ring is fixedly sleeved on the surface of the movable slide rod, and the limit ring is located at the bottom of the iron core. When the electromagnetic coil is energized, it controls the movable slide rod inside the iron core to move downward, and a reset spring is movably sleeved on the surface of the movable slide rod, and the reset spring is located at the top of the iron core. The electromagnetic coil is electrically connected to the control module.

[0009] As a preferred solution of the exfoliated cell adhesion sampling device described in the present invention, the adhesion device includes an elastomer, the surface of the elastomer is movably connected to the inner wall of the storage tube, a slot is provided on the top of the elastomer, the inner diameter of the slot is matched with the diameter of the bottom of the movable sliding rod, the bottom of the elastomer is fixedly connected to a adhesion seat, and the bottom of the adhesion seat is fixedly connected to a rubber surface body.

[0010] As a preferred solution of the exfoliated cell adhesion sampling device described in the present invention, wherein: the feeding assembly includes a knob, the knob is rotatably connected to the surface of the conical tube, the rear side of the knob is fixedly connected to a rotating rod, the rotating rod is rotatably connected to the inner wall of the conical tube, the rotating rod surface is fixedly sleeved with a swinging piece, one end of the swinging piece is provided with a chuck, the other end of the swinging piece is provided with a material dividing claw, one end of the chuck is fixedly connected with an elastic arc piece, the elastic arc piece is movably connected to the surface of the elastomer for limiting the elastomer, one end of the material dividing claw is provided with a claw head, the claw head is movably connected to the bottom of the elastomer for controlling the falling of the elastomer.

[0011] As a preferred solution of the exfoliated cell adhesion sampling device of the present invention, wherein: a rotating mechanism is sleeved on the surface of the sampler, and a plurality of rapid filling mechanisms are fixedly connected to the surface of the rotating mechanism.

[0012] As a preferred embodiment of the exfoliated cell adhesion sampling device described in the present invention, the rotating mechanism includes a swivel, the swivel is movably sleeved on the surface of the shell, the bottom of the swivel is rotatably connected to a magnetic seat, the magnetic seat is fixedly sleeved on the surface of the shell, a plurality of magnetic parts are installed inside the magnetic seat, the magnetic parts are magnetically connected to the swivel, a plurality of anti-slip protrusions are provided on the top of the swivel surface, and a connecting arm is fixedly connected to the swivel surface.

[0013] As a preferred solution of the exfoliated cell adhesion sampling device described in the present invention, wherein: the rapid filling mechanism includes a filling tube, a fixed arm is fixedly connected to the surface of the filling tube, the fixed arm is fixedly connected to the connecting arm, the filling tube is located at the top of the storage tube, the bottom of the filling tube is aligned with the top of the storage tube, the top threaded sleeve of the filling tube is provided with a threaded cover, the bottom of the filling tube is fixedly connected to a discharge assembly, the bottom of the filling tube surface is fixedly connected to a positioning assembly, and the inside of the filling tube is movably connected to a pushing assembly.

[0014] As a preferred solution of the exfoliated cell adhesion sampling device of the present invention, the discharging assembly includes a fixing ring, the fixing ring is fixedly installed at the bottom of the filling tube, a rubber ring is fixedly connected to the inner wall of the fixing ring, a plurality of rubber sheets are arranged inside the rubber ring, and a petal groove is arranged on the opposite side of the rubber sheet; The positioning assembly comprises a sliding seat, the sliding seat is fixedly mounted on the bottom of the fixed ring surface, a positioning pin is fixedly connected to the top of the sliding seat inner cavity, a spring is movably sleeved on the surface of the positioning pin, a fixing piece is fixedly connected to the bottom of the spring, a stop pin is fixedly connected to the bottom of the sliding seat in a sliding manner, and a surface of the stop pin is movably connected to the surface of the storage tube; The pushing assembly includes a pushing cylinder, the surface of which is movably connected to the inner wall of the storage tube, the bottom of which is provided with a rounded corner, the surface of which is fixedly connected to a pushing handle, the surface of the stuffing tube is provided with a sliding cavity used in conjunction with the pushing handle, the surface of the pushing handle is fixedly connected to a damping ring, and the damping ring is movably sleeved on the surface of the stuffing tube.

[0015] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention rotates the material discharge component so that the picker falls from the storage tube into the conical tube. When the material discharge component is rotated, the swinging member is rotated upward by the knob and the rotating rod. The swinging member drives the chuck and the material separation claw to swing slightly at the same time. The chuck drives the elastic arc-shaped sheet to swing downward and contact the surface of the elastic body to squeeze the elastic body downward. Then the material separation claw drives the claw head to swing upward, releasing the limit on the elastic body at the bottom, so that the picker at the bottom can enter the inner cavity of the conical tube. After the feeding is completed, the material discharge component is reset, and the material discharge component continues to fix the picker.

[0016] 2. The present invention can detect the adhesive collector by setting an annular proximity sensor and transmit the detection signal to the control module. The control module controls the electromagnetic coil to work, and the charging module and the power supply system power the control module, the annular proximity sensor and the electromagnetic coil. During the operation of the electromagnetic coil, a strong magnetic field is generated. This magnetic field acts on the iron core and the movable slide bar. The movable slide bar is made of ferromagnetic material. Due to the effect of electromagnetic attraction, the movable slide bar begins to overcome the resistance of the reset spring and moves downward along the inner wall of the iron core. Finally, the bottom of the movable slide bar is inserted into the card slot, driving the elastomer and the adhesive collector to move downward. The bottom of the adhesive collector extends out of the conical tube and drives the rubber surface body to contact the detached cell tissue to sample the cell tissue. During the sampling process, the electromagnetic coil is controlled to be powered on and off. When the power is off, the reset spring drives the movable slide bar to reset, so that the adhesive collector moves upward. When the power is on, the movable slide bar drives the adhesive collector to move downward to realize the rapid lifting and lowering of the adhesive collector, and multiple adhesive collections are performed on a target area. After the adhesive collection is completed, the adhesive collector is pushed out from the bottom of the conical tube by the movable slide bar, which is convenient for removing the adhesive collector. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the structure of the sampler of the present invention; Figure 2 It is a schematic diagram of the cross-sectional structure of the sampler of the present invention; Figure 3 It is a schematic diagram of the structure of the blanking assembly of the present invention; Figure 4 The structure of the adhesive extractor of the present invention is shown in FIG. Figure 1 ; Figure 5 The structure of the adhesive extractor of the present invention is shown in FIG. Figure 2 ; Figure 6 is a cross-sectional view of a sampler of the present invention; Figure 7 For the present invention Figure 6 A magnified view of middle; Figure 8 It is a schematic diagram of the falling state of the adhesive extractor of the present invention; Fig. 9It is a schematic diagram of the assembly state of the adhesive extractor and the movable slide rod of the present invention; Fig.10 It is a schematic diagram of the adhesive extractor of the present invention in the rising state; Fig.11 It is a schematic diagram of the structure of the sampler, the rotating mechanism and the rapid filling mechanism of the present invention; Fig.12 It is an exploded view of the rotating mechanism of the present invention; Fig.13 It is a structural schematic diagram of the rapid filling mechanism of the present invention; Fig.14 It is a schematic cross-sectional view of the quick filling mechanism of the present invention; Fig.15 It is a schematic diagram of the structure of the pusher assembly of the present invention; Fig.16 It is a schematic diagram of the structure of the discharging assembly of the present invention; Fig.17 It is a schematic cross-sectional structure diagram of the positioning assembly of the present invention.

[0018] In the figure: 100, sampler; 101, shell; 102, conical tube; 103, storage tube; 104, adhesive; 1041, elastic body; 1042, slot; 1043, adhesive seat; 1044, rubber surface; 105, blanking assembly; 1051, knob; 1052, rotating rod; 1053, swinging member; 1054, chuck; 1055, elastic arc sheet; 1056, material separation claw; 1057, claw head; 106, closing cover; 107, control module; 108, power supply system; 109, charging module; 110, iron core; 111, electromagnetic coil; 112, movable slide; 113, annular proximity sensor; 114, reset spring; 115, limit ring; 200, rotating mechanism; 201, swivel; 202, connecting arm; 203, magnetic seat; 204, magnetic part; 205, anti-skid protrusion; 300, quick filling mechanism; 301, filling tube; 302, fixed arm; 303, discharging assembly; 3031, fixing ring; 3032, rubber ring; 3033, rubber sheet; 3034, petal groove; 304, positioning assembly; 3041, sliding seat; 3042, positioning pin; 3043, spring; 3044, fixing part; 3045, stop pin; 305, threaded cover; 306, pushing assembly; 3061, pushing cylinder; 3062, pushing handle; 3063, fillet; 3064, damping collar; 307, sliding cavity. DETAILED DESCRIPTION

[0019] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0020] like Figure 1-Figure 10As shown, this embodiment provides an exfoliated cell adhesion sampling device, including a sampler 100, the sampler 100 includes a shell 101, a conical tube 102 and a storage tube 103, the conical tube 102 is fixedly installed on the bottom of the shell 101 and is connected thereto, the storage tube 103 is fixedly installed on the surface of the conical tube 102 and is connected thereto, and the storage tube 103 is arranged at an angle.

[0021] Furthermore, a plurality of adhesives 104 are provided in the inner cavity of the storage tube 103, a material discharge assembly 105 is rotatably connected to the conical tube 102, and the material discharge assembly 105 is movably connected to the adhesive 104 for controlling the falling of the adhesive 104, and an annular proximity sensor 113 is fixedly installed at the bottom of the shell 101, and the annular proximity sensor 113 detects the falling adhesive 104.

[0022] Furthermore, a closing cover 106 is threadedly connected to the top of the housing 101 , and a control module 107 is fixedly installed inside the closing cover 106 . The control module 107 is electrically connected to the annular proximity sensor 113 .

[0023] Furthermore, a touch switch is provided on the top of the control module 107 .

[0024] Furthermore, a power supply system 108 is fixedly installed in the inner cavity of the shell 101 , and a charging module 109 electrically connected to the power supply system 108 is fixedly installed on the power supply system 108 , and the charging module 109 penetrates the surface of the shell 101 .

[0025] Furthermore, an iron core 110 is fixedly connected to the bottom of the inner cavity of the shell 101, an electromagnetic coil 111 is sleeved on the surface of the iron core 110, a movable slide rod 112 is movably connected inside the iron core 110, a limit ring 115 is fixedly sleeved on the surface of the movable slide rod 112, and the limit ring 115 is located at the bottom of the iron core 110. When the electromagnetic coil 111 is energized, it controls the movable slide rod 112 inside the iron core 110 to move downward, a return spring 114 is movably sleeved on the surface of the movable slide rod 112, and the return spring 114 is located at the top of the iron core 110, and the electromagnetic coil 111 is electrically connected to the control module 107.

[0026] Furthermore, the adhesive device 104 includes an elastomer 1041, the surface of the elastomer 1041 is movably connected to the inner wall of the storage tube 103, a slot 1042 is provided on the top of the elastomer 1041, the inner diameter of the slot 1042 is adapted to the diameter of the bottom of the movable slide rod 112, an adhesive seat 1043 is fixedly connected to the bottom of the elastomer 1041, and a rubber surface body 1044 is fixedly connected to the bottom of the adhesive seat 1043.

[0027] Furthermore, the unloading component 105 includes a knob 1051, which is rotatably connected to the surface of the conical tube 102. A rotating rod 1052 is fixedly connected to the rear side of the knob 1051. The rotating rod 1052 is rotatably connected to the inner wall of the conical tube 102. A swinging piece 1053 is fixedly sleeved on the surface of the rotating rod 1052. A chuck 1054 is provided at one end of the swinging piece 1053, and a material dividing claw 1056 is provided at the other end of the swinging piece 1053. An elastic arc piece 1055 is fixedly connected to one end of the chuck 1054. The elastic arc piece 1055 is movably connected to the surface of the elastomer 1041 for limiting the position of the elastomer 1041. A claw head 1057 is provided at one end of the material dividing claw 1056. The claw head 1057 is movably connected to the bottom of the elastomer 1041 for controlling the falling of the elastomer 1041.

[0028] When the exfoliated cell tissue is to be adhered, the unloading component 105 is rotated to make the adhesive 104 fall from the inside of the storage tube 103 into the conical tube 102. When the unloading component 105 is rotated, the swinging piece 1053 is rotated upward by the knob 1051 and the rotating rod 1052. The swinging piece 1053 simultaneously drives the chuck 1054 and the material dividing claw 1056 to swing slightly. The chuck 1054 drives the elastic arc piece 1055 to swing downward and contact the surface of the elastomer 1041 to squeeze the elastomer 1041 downward. Then the material dividing claw 1056 drives the claw head 1057 to swing upward, releasing the limit on the bottom elastomer 1041, so that the adhesive 104 at the bottom can enter the inner cavity of the conical tube 102. After the feeding is completed, the unloading component 105 is reset, and the unloading component 105 continues to fix the adhesive 104.

[0029] When the picker 104 falls to the bottom of the inner cavity of the conical tube 102, the annular proximity sensor 113 detects the picker 104 and transmits the detection signal to the control module 107. The control module 107 controls the electromagnetic coil 111 to work. The charging module 109 and the power supply system 108 power the control module 107, the annular proximity sensor 113 and the electromagnetic coil 111. During the operation of the electromagnetic coil 111, a strong magnetic field will be generated. This magnetic field acts on the iron core 110 and the movable slide 112. The movable slide 112 is made of ferromagnetic material. Due to the effect of electromagnetic attraction, the movable slide 112 begins to overcome the resistance of the reset spring 114 and moves downward along the inner wall of the iron core 110. Finally, the movable slide 112 The bottom is inserted into the card slot 1042, driving the elastic body 1041 and the adhesive seat 1043 to move downward, the bottom of the adhesive seat 1043 extends out of the conical tube 102, and drives the rubber surface body 1044 to contact the detached cell tissue to sample the cell tissue. During the sampling process, the electromagnetic coil 111 is controlled to be powered on and off. When the power is off, the reset spring 114 drives the movable slide bar 112 to reset, so that the adhesive device 104 moves upward. When the power is on, the movable slide bar 112 drives the adhesive device 104 to move downward to achieve rapid lifting of the adhesive device 104, and multiple adhesives are performed on a target area. After the adhesive is completed, the adhesive device 104 is pushed out from the bottom of the conical tube 102 by the movable slide bar 112 to facilitate the removal of the adhesive device.

[0030] For further information, please refer to Figure 11-17 A rotating mechanism 200 is sleeved on the surface of the sampler 100, and a plurality of quick filling mechanisms 300 are fixedly connected to the surface of the rotating mechanism 200.

[0031] Furthermore, the rotating mechanism 200 includes a rotating ring 201, which is movably mounted on the surface of the shell 101. The bottom of the rotating ring 201 is rotatably connected to a magnetic seat 203, which is fixedly mounted on the surface of the shell 101. A plurality of magnetic parts 204 are installed inside the magnetic seat 203, and the magnetic parts 204 are magnetically connected to the rotating ring 201. A plurality of anti-slip protrusions 205 are provided on the top of the surface of the rotating ring 201, and a connecting arm 202 is fixedly connected to the surface of the rotating ring 201.

[0032] Furthermore, the swivel 201 is made of iron metal material.

[0033] Furthermore, the quick filling mechanism 300 includes a filling tube 301, a fixed arm 302 is fixedly connected to the surface of the filling tube 301, the fixed arm 302 is fixedly connected to the connecting arm 202, the filling tube 301 is located at the top of the storage tube 103, the bottom of the filling tube 301 is aligned with the top of the storage tube 103, a threaded cover 305 is provided on the top threaded sleeve of the filling tube 301, a discharge assembly 303 is fixedly connected to the bottom of the filling tube 301, a positioning assembly 304 is fixedly connected to the bottom of the surface of the filling tube 301, and a pushing assembly 306 is movably connected inside the filling tube 301.

[0034] Furthermore, the discharging assembly 303 includes a fixing ring 3031, which is fixedly installed at the bottom of the filling tube 301, and a rubber ring 3032 is fixedly connected to the inner wall of the fixing ring 3031. A plurality of rubber sheets 3033 are arranged inside the rubber ring 3032, and a petal groove 3034 is arranged on the opposite side of the rubber sheet 3033.

[0035] Furthermore, the positioning assembly 304 includes a sliding seat 3041, which is fixedly installed on the bottom of the surface of the fixing ring 3031, and the top of the inner cavity of the sliding seat 3041 is fixedly connected with a positioning pin 3042, and the surface of the positioning pin 3042 is movably sleeved with a spring 3043, and the bottom of the spring 3043 is fixedly connected with a fixing piece 3044, and the bottom of the fixing piece 3044 is fixedly connected with a stop pin 3045, and the stop pin 3045 is slidably connected to the bottom of the sliding seat 3041, and the surface of the stop pin 3045 is movably connected to the surface of the storage tube 103.

[0036] Furthermore, the pushing assembly 306 includes a pushing cylinder 3061, the surface of which is movably connected to the inner wall of the storage tube 103, a rounded corner 3063 is provided at the bottom of the pushing cylinder 3061, a pushing handle 3062 is fixedly connected to the surface of the pushing cylinder 3061, a sliding cavity 307 for use with the pushing handle 3062 is provided on the surface of the filling tube 301, a damping ring 3064 is fixedly connected to the surface of the pushing handle 3062, and the damping ring 3064 is movably sleeved on the surface of the filling tube 301.

[0037] When the adhesive dispenser 104 needs to be replenished, the rotating mechanism 200 is first assembled, the rotating ring 201 is placed on the surface of the storage tube 103, and is placed on the magnetic seat 203. The magnetic part 204 inside the magnetic seat 203 magnetically attracts the rotating ring 201, so that the rotating ring 201 can be adsorbed on the magnetic seat 203 and rotate on the top of the magnetic seat 203. The rotating ring 201 drives several quick filling mechanisms 300 to rotate simultaneously through the connecting arm 202 to replenish the adhesive dispenser 104.

[0038] The inside of the filling tube 301 of the quick filling mechanism 300 is filled with a number of sticking devices 104 in advance, and then the pushing assembly 306 is installed on the top of the inner cavity of the filling tube 301, and the threaded cover 305 is screwed on the top of the filling tube 301 to limit the top of the pushing assembly 306. When the filling tube 301 moves to the top of the storage tube 103, the positioning assembly 304 contacts the surface of the storage tube 103 to limit the filling tube 301 so that the filling tube 301 and the storage tube 103 can be aligned, and the pushing assembly 306 is moved inside the sliding cavity 307 and the filling tube 301. The pushing assembly 306 drives the several sticking devices 104 to move downward, and the sticking devices 104 pass through the discharge assembly 303 and enter into the storage tube 103 to quickly fill the inside of the storage tube 103.

[0039] When the positioning assembly 304 is limiting, the surface of the stop pin 3045 contacts the surface of the storage tube 103 to prevent the filling tube 301 from excessive rotation. When the filling is completed and the storage tube 103 needs to be rotated further, the stop pin 3045 is moved upward. The stop pin 3045 compresses the spring 3043 through the fixing part 3044, and the positioning pin 3042 limits the top of the spring 3043. When the stop pin 3045 retracts to the inside of the sliding seat 3041, it is away from the surface of the storage tube 103, so that the filling tube 301 can continue to rotate.

[0040] During the operation of the pushing assembly 306, the pushing cylinder 3061 is moved downward by the pushing handle 3062, the pushing handle 3062 slides inside the sliding cavity 307, and the damping ring 3064 slides on the surface of the filling tube 301, thereby increasing the damping of the pushing cylinder 3061 during its movement, so that the feeding can be stable. The rounded corner 3063 at the bottom of the pushing cylinder 3061 contacts the top of the sticking device 104 to drive several sticking devices 104 to move downward. By setting the rounded corner 3063, it is easy to insert the pushing cylinder 3061 into the storage tube 103.

[0041] During the operation of the discharge component 303, the fixing ring 3031 fixes the rubber ring 3032, the adhesive seat 1043 first passes through the rubber sheet 3033, and then the elastic body 1041 passes through the rubber sheet 3033. When the adhesive 104 passes through the rubber sheet 3033, several rubber sheets 3033 are deformed outward, so that several petal grooves 3034 are connected, and a discharge channel is formed inside the rubber ring 3032. The adhesive 104 enters the storage tube 103 through the discharge channel. When the entry is completed, the rubber sheet 3033 automatically resets to seal the inside of the rubber ring 3032 to prevent the adhesive 104 from passing through the discharge component 303 and falling.

Claims

1. A device for collecting and sampling exfoliated cells, comprising a sampler (100), characterized in that: The sampler (100) comprises a housing (101), a conical tube (102) and a storage tube (103); the conical tube (102) is fixedly mounted on the bottom of the housing (101) and is in communication with the housing; the storage tube (103) is fixedly mounted on the surface of the conical tube (102) and is in communication with the housing; and the storage tube (103) is arranged at an angle; The inner cavity of the storage tube (103) is provided with a plurality of sticking devices (104); a material discharge assembly (105) is rotatably connected to the conical tube (102); the material discharge assembly (105) is movably connected to the sticking devices (104) and is used to control the falling of the sticking devices (104); an annular proximity sensor (113) is fixedly mounted on the bottom of the shell (101); the annular proximity sensor (113) detects the falling sticking devices (104).

2. The exfoliated cell collection and sampling device according to claim 1, characterized in that: A closing cover (106) is threadedly connected to the top of the housing (101), a control module (107) is fixedly installed inside the closing cover (106), and the control module (107) is electrically connected to the annular proximity sensor (113).

3. The exfoliated cell adhesion sampling device according to claim 2, characterized in that: A power system (108) is fixedly installed in the inner cavity of the shell (101), and a charging module (109) electrically connected to the power system (108) is fixedly installed on the power system (108), and the charging module (109) penetrates the surface of the shell (101).

4. The exfoliated cell adhesion sampling device according to claim 3, characterized in that: An iron core (110) is fixedly connected to the bottom of the inner cavity of the shell (101), an electromagnetic coil (111) is sleeved on the surface of the iron core (110), a movable slide bar (112) is movably connected inside the iron core (110), a limit ring (115) is fixedly sleeved on the surface of the movable slide bar (112), and the limit ring (115) is located at the bottom of the iron core (110). When the electromagnetic coil (111) is energized, it controls the movable slide bar (112) inside the iron core (110) to move downward, a return spring (114) is movably sleeved on the surface of the movable slide bar (112), and the return spring (114) is located at the top of the iron core (110), and the electromagnetic coil (111) is electrically connected to the control module (107).

5. The exfoliated cell collection and sampling device according to claim 4, characterized in that: The adhesive remover (104) comprises an elastic body (1041), the surface of the elastic body (1041) is movably connected to the inner wall of the storage tube (103), a slot (1042) is provided on the top of the elastic body (1041), the inner diameter of the slot (1042) is matched with the diameter of the bottom of the movable slide rod (112), the bottom of the elastic body (1041) is fixedly connected to an adhesive removal seat (1043), and the bottom of the adhesive removal seat (1043) is fixedly connected to a rubber surface body (1044).

6. The exfoliated cell collection and sampling device according to claim 5, characterized in that: The blanking assembly (105) comprises a knob (1051), the knob (1051) being rotatably connected to the surface of the conical tube (102), a rotating rod (1052) being fixedly connected to the rear side of the knob (1051), the rotating rod (1052) being rotatably connected to the inner wall of the conical tube (102), a swinging member (1053) being fixedly sleeved on the surface of the rotating rod (1052), a chuck (1054) being provided at one end of the swinging member (1053), and the swinging member (1053) being fixedly sleeved on the surface of the rotating rod (1052). ) is provided with a material dividing claw (1056) at the other end, one end of the clamp (1054) is fixedly connected to an elastic arc-shaped piece (1055), the elastic arc-shaped piece (1055) is movably connected to the surface of the elastic body (1041) and is used to limit the elastic body (1041), and one end of the material dividing claw (1056) is provided with a claw head (1057), the claw head (1057) is movably connected to the bottom of the elastic body (1041) and is used to control the falling of the elastic body (1041).

7. The exfoliated cell collection and sampling device according to claim 6, characterized in that: The surface of the sampler (100) is sleeved with a rotating mechanism (200), and the surface of the rotating mechanism (200) is fixedly connected with a plurality of quick filling mechanisms (300).

8. The exfoliated cell collection and sampling device according to claim 7, characterized in that: The rotating mechanism (200) comprises a rotating ring (201), the rotating ring (201) is movably sleeved on the surface of the shell (101), the bottom of the rotating ring (201) is rotatably connected to a magnetic seat (203), the magnetic seat (203) is fixedly sleeved on the surface of the shell (101), a plurality of magnetic parts (204) are installed inside the magnetic seat (203), the magnetic parts (204) are magnetically connected to the rotating ring (201), a plurality of anti-slip protrusions (205) are provided on the top of the surface of the rotating ring (201), and a connecting arm (202) is fixedly connected to the surface of the rotating ring (201).

9. The exfoliated cell collection and sampling device according to claim 8, characterized in that: The quick filling mechanism (300) comprises a filling tube (301), a fixed arm (302) is fixedly connected to the surface of the filling tube (301), the fixed arm (302) is fixedly connected to the connecting arm (202), the filling tube (301) is located at the top of the storage tube (103), the bottom of the filling tube (301) is aligned with the top of the storage tube (103), a threaded cover (305) is provided on the top of the filling tube (301), a discharging assembly (303) is fixedly connected to the bottom of the filling tube (301), a positioning assembly (304) is fixedly connected to the bottom of the surface of the filling tube (301), and a pushing assembly (306) is movably connected inside the filling tube (301).

10. The exfoliated cell collection and sampling device according to claim 9, characterized in that: The discharge assembly (303) comprises a fixing ring (3031), the fixing ring (3031) being fixedly mounted on the bottom of the filling tube (301), a rubber ring (3032) being fixedly connected to the inner wall of the fixing ring (3031), a plurality of rubber sheets (3033) being arranged inside the rubber ring (3032), and a petal groove (3034) being arranged on the opposite side of the rubber sheet (3033); The positioning assembly (304) comprises a sliding seat (3041), the sliding seat (3041) is fixedly mounted on the bottom of the surface of the fixing ring (3031), a positioning pin (3042) is fixedly connected to the top of the inner cavity of the sliding seat (3041), a spring (3043) is movably sleeved on the surface of the positioning pin (3042), a fixing piece (3044) is fixedly connected to the bottom of the spring (3043), a stop pin (3045) is fixedly connected to the bottom of the fixing piece (3044), the stop pin (3045) is slidably connected to the bottom of the sliding seat (3041), and the surface of the stop pin (3045) is movably connected to the surface of the storage tube (103); The pushing assembly (306) comprises a pushing cylinder (3061), the surface of which is movably connected to the inner wall of the storage tube (103), the bottom of which is provided with a rounded corner (3063), the surface of which is fixedly connected to a pushing handle (3062), the surface of which is provided with a sliding cavity (307) for use with the pushing handle (3062), the surface of which is fixedly connected to a damping collar (3064), and the damping collar (3064) is movably sleeved on the surface of the filling tube (301).

Images