Liquid sucking device and liquid changing system

Abstract

The invention relates to the field of in-vitro diagnosis automation equipment, in particular to a liquid sucking device and a liquid changing system. A liquid suction device comprises a confluence piece, a first liquid suction assembly, a second liquid suction assembly and a liquid suction driving assembly. The first liquid suction assembly is used for sucking liquid above a first liquid level in the container, and the first liquid suction assembly is communicated with the confluence piece; the second liquid suction assembly is located on the downstream of the first liquid suction assembly and used for sucking liquid above a second liquid level in the container, the second liquid level is lower than the first liquid level, and the second liquid suction assembly is communicated with the confluence piece; the liquid suction driving assembly is in driving connection with the first liquid suction assembly and the second liquid suction assembly so that the first liquid suction assembly and the second liquid suction assembly can sequentially suck liquid in the container and convey the liquid to the confluence piece. The liquid suction device is high in liquid suction efficiency, short in consumed time and capable of improving the instrument testing speed.

Description

Technical Field

[0001] The present application relates to the field of in vitro diagnostic automation equipment, and in particular to a liquid aspiration device and a liquid replacement system. Background Art

[0002] In order to separate free and immune complex markers, the fully automatic chemiluminescence immunoassay analyzer needs to go through multiple cleaning stages, each of which includes aspirating waste liquid and injecting new liquid once. However, the current waste liquid aspirating device is inefficient and time-consuming, which affects the instrument's testing speed.

[0003] The information disclosed in this background technology section is only intended to enhance the understanding of the overall background of the invention and should not be regarded as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to a person skilled in the art. Summary of the invention

[0004] Based on this, it is necessary to provide a liquid suction device and a liquid replacement system to address the problems that the current waste liquid suction device is inefficient, time-consuming, and affects the instrument testing speed.

[0005] In a first aspect, a liquid suction device comprises:

[0006] Busbars;

[0007] A first liquid suction component, the first liquid suction component is used to suck liquid above a first liquid level in the container, and the first liquid suction component is connected to the manifold;

[0008] a second liquid-absorbing component, the second liquid-absorbing component being located downstream of the first liquid-absorbing component, the second liquid-absorbing component being used to absorb liquid above a second liquid level in the container, the second liquid level being lower than the first liquid level, the second liquid-absorbing component being in communication with the manifold; and

[0009] The liquid suction driving component is drivingly connected to the first liquid suction component and the first liquid suction component, so that the first liquid suction component and the second liquid suction component suck the liquid in the container in turn and transport it to the conduit.

[0010] In one embodiment, the first pipetting component includes a first pipetting needle, and the second pipetting component includes a second pipetting needle. Along the liquid level height direction of the container, the bottom end of the second pipetting needle is lower than the first pipetting needle.

[0011] In one embodiment, the first pipette component further includes a first pipette needle seat, the second pipette component further includes a second pipette needle seat, the first pipette needle is disposed on the first pipette needle seat, and the second pipette needle seat is disposed on the second pipette needle seat.

[0012] In one embodiment, the liquid suction drive assembly includes a first liquid suction drive member and a second liquid suction drive member, the first liquid suction drive member is drivingly connected to the first liquid suction assembly so that the first liquid suction assembly absorbs the liquid in the container and transports it to the collection piece; the second liquid suction drive member is drivingly connected to the second liquid suction assembly so that the second liquid suction assembly absorbs the liquid in the container and transports it to the collection piece.

[0013] In one embodiment, the first liquid suction drive member includes a first peristaltic pump, which is driven and connected to the first liquid suction component, and the second liquid suction member includes a second peristaltic pump, which is driven and connected to the second liquid suction component.

[0014] In one embodiment, the manifold includes a main channel and a first liquid inlet and a second liquid inlet connected to the main channel, the main channel has a liquid outlet at one end along its length direction, the first liquid inlet and the second liquid inlet are arranged on both sides of the main channel along its length direction, the first liquid inlet is connected to the first liquid absorption component, and the second liquid inlet is connected to the second liquid absorption component.

[0015] In one embodiment, the first liquid inlet and the second liquid inlet are staggered.

[0016] In one embodiment, the first liquid inlet includes a plurality of ports, and the second liquid inlet includes a plurality of ports. Along the length direction of the main road, all of the first liquid inlets and all of the second liquid inlets are spaced apart, and the first liquid inlet is located between two adjacent second liquid inlets.

[0017] In one embodiment, the diameter of the main channel is D, and the diameter of the first liquid inlet or the second liquid inlet is d, satisfying: D≥1.5d.

[0018] In a second aspect, a fluid exchange system is provided, comprising the fluid aspiration device as described in the first aspect.

[0019] The above-mentioned liquid suction device is provided with a first liquid suction component and a second liquid suction component, which are respectively responsible for sucking liquids at different liquid levels. Compared with a single liquid suction structure, this layered suction method can clean the waste liquid in the reaction container more accurately and quickly. The first liquid suction component first processes the waste liquid above the first liquid level, and then the second liquid suction component processes the liquid above the relatively lower second liquid level, so as to avoid excessive waste liquid remaining due to a single suction, reduce the time-consuming operation of repeatedly sucking the same position, and improve the overall liquid suction efficiency. The liquid suction drive component drives the first liquid suction component and the second liquid suction component at the same time, and allows the two to operate in sequence. This integrated drive design optimizes the continuity of the liquid suction process, reduces the delay and jamming when different components are connected, and compared with the traditional step-by-step operation device, it can complete the liquid suction action compactly and orderly, saving time, thereby helping the fully automatic chemiluminescence immunoassay to speed up the test speed. The introduction of a confluence piece allows the liquids sucked by the first liquid suction component and the second liquid suction component to converge here. The confluence design simplifies the collection path of waste liquid, avoids the complicated process and resistance loss caused by multi-pipeline decentralized drainage, makes the aspiration process smoother and more efficient, helps to shorten the aspiration time, and indirectly improves the instrument testing efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the conventional technology, the drawings required for use in the embodiments or the conventional technology descriptions are briefly introduced below. Obviously, the drawings described below are merely embodiments of the present application, and ordinary technicians in this field can obtain other drawings based on the disclosed drawings without paying any creative work.

[0021] FIG. 1 is a schematic diagram of a liquid aspiration device provided in an embodiment of the present application.

[0022] FIG. 2 is a schematic diagram of another liquid aspiration device provided in an embodiment of the present application.

[0023] FIG. 3 is a schematic diagram of a current collector provided in an embodiment of the present application.

[0024] Explanation of the reference numerals: 100, liquid aspiration device; 1, conduit; 11, main channel; 12, first liquid inlet; 13, second liquid inlet; 14, liquid outlet; 2, first liquid aspiration assembly; 21, first liquid aspiration needle; 22, first liquid aspiration needle seat; 3, second liquid aspiration assembly; 31, second liquid aspiration needle; 32, second liquid aspiration needle seat; 4, liquid aspiration drive assembly; 41, first liquid aspiration drive member; 42, second liquid aspiration drive member; 5, container. DETAILED DESCRIPTION

[0025] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific embodiments disclosed below.

[0026] In the detection process of the fully automatic chemiluminescence immunoassay, the effective separation of free markers and immune complex markers can ensure the high accuracy of the test results. To achieve separation, conventional operations rely on a cleaning and separation procedure, which aims to remove unbound components in the reactant system, especially free labeled antigens and antibodies. Cleaning and separation mainly include two steps: aspiration and injection. In essence, aspiration is the use of the negative pressure principle to accurately remove redundant components that do not participate in the reaction in the reaction vessel, namely waste liquid; injection is based on a fluid transport mechanism to accurately inject appropriate cleaning buffer into the reaction vessel after the waste liquid is emptied. In view of the accuracy requirements of immunoassay, the cleaning and separation process often needs to go through three or more rounds to ensure the thoroughness of impurity removal. The current aspiration device takes a long time to pump and has low working efficiency, which affects the speed of the analyzer.

[0027] Please refer to Figures 1 and 2. Based on the above problems, in the first aspect, the embodiment of the present application provides a liquid suction device 100, including a manifold 1, a first liquid suction component 2, a second liquid suction component 3 and a liquid suction drive component 4. The first liquid suction component 2 is used to suck liquid above a first liquid level in a container 5, and the first liquid suction component 2 is connected to the manifold 1. The second liquid suction component 3 is located downstream of the first liquid suction component 2. The second liquid suction component 3 is used to suck liquid above a second liquid level in the container 5, the second liquid level is lower than the first liquid level, and the second liquid suction component 3 is connected to the manifold 1. The liquid suction drive component 4 is driven and connected to the first liquid suction component 2 and the first liquid suction component 2, so that the first liquid suction component 2 and the second liquid suction component 3 successively suck the liquid in the container 5 and transport it to the manifold 1. Please refer to the A direction in Figures 1 and 2, which is the moving direction of the container 5. The container 5 containing the liquid to be absorbed moves toward the first absorption component 2 and the second absorption component 3. The container 5 first moves to the bottom of the first absorption component 2, and the absorption drive component 4 drives the first absorption component 2 to absorb the liquid above the first liquid level in the container 5 and transfer it to the manifold 1. Then the container 5 moves to the bottom of the second absorption component 3, and the absorption drive component 4 drives the second absorption component 3 to absorb the liquid above the second liquid level in the container 5 and transfer it to the manifold 1.

[0028] The first liquid absorption component 2 and the second liquid absorption component 3 are set to absorb waste liquid at different liquid levels respectively, and multi-stage liquid absorption can be achieved to improve the absorption efficiency. Compared with a single liquid absorption device 100, this layered liquid absorption can clean the waste liquid in the reaction container 5 more comprehensively and quickly. The first liquid absorption component 2 first processes the waste liquid above the first liquid level, and the remaining low-level waste liquid is then processed by the second liquid absorption component 3, reducing the single liquid absorption residue, avoiding repeated suction of the same area, greatly shortening the overall suction time, and improving the liquid absorption efficiency. Equipped with a liquid absorption drive component 4, the first and second liquid absorption components 3 are uniformly driven to operate in sequence, and the integrated drive optimization process is integrated. The components of the traditional liquid absorption device 100 have poor synergy and time-consuming connection. However, the device can make the liquid absorption process compact and coherent through the liquid absorption drive component 4, reduce the time loss caused by component switching and startup pauses, and enable the liquid absorption operation to be completed quickly and orderly, accelerate the entire cleaning and separation process, and thus improve the analyzer speed. The introduction of the manifold 1 to gather the liquids absorbed by the two liquid absorbing components can simplify the collection of waste liquid. In the past, multiple liquid absorbing lines may correspond to multiple waste liquid collection paths, which is not only complicated but also easy to generate resistance, slowing down the liquid absorbing speed. The manifold 1 integrates the flow direction of the waste liquid, making the waste liquid transportation smoother, reducing the fluid transmission resistance, further helping to improve the liquid absorbing efficiency, and indirectly solving the problem of the time-consuming and low efficiency of the existing liquid absorbing device 100.

[0029] In an optional embodiment, the first liquid suction assembly 2 can be lowered by a lifting device to absorb liquid above a first liquid level in the container 5, and the second liquid suction assembly 3 can also be lowered by a lifting device to absorb liquid above a second liquid level in the container 5. Exemplarily, the lifting device can be a linear module, such as a ball screw linear module, a synchronous belt linear module, a gear rack linear module, etc.

[0030] Please refer to Figures 1 and 2. In other optional embodiments, the first liquid suction component 2 includes a first liquid suction needle 21, and the second liquid suction component 3 includes a second liquid suction needle 31. Along the liquid level height direction of the container 5, the bottom of the second liquid suction needle 31 is lower than the first liquid suction needle 21. The bottom end of the second liquid suction needle 31 is lower than the first liquid suction needle 21, and the bottom end of the second liquid suction needle 31 can extend into a deeper position of the container 5, so it can absorb liquid above the second liquid level. The first liquid suction needle 21 and the second liquid suction needle 31 of fixed height do not need to wait for the lifting action, and can directly absorb liquid, so that the liquid suction link of each round of cleaning and separation is more compact, and the overall detection process is accelerated. The first liquid suction needle 21 and the second liquid suction needle 31 are set according to different liquid level heights, which simplifies the mechanical structure, makes the equipment more compact and small, and is conducive to reasonable layout in the limited space inside the instrument, which is convenient for later maintenance. The first liquid suction needle 21 and the second liquid suction needle 31 are fixedly installed, with higher stability, ensuring long-term stable and accurate operation of the instrument. Since the position of the aspiration needle is fixed, it can stably and accurately aspirate liquid above the target liquid level, avoiding the problem of inaccurate aspiration position caused by positioning deviation of the lifting device or interference from factors such as mechanical transmission clearance and wear, thereby improving the accuracy and reliability of the aspiration process.

[0031] Refer to Fig. 1 and Fig. 2, in some embodiments, the first liquid suction assembly 2 also includes a first liquid suction needle seat 22, the second liquid suction assembly 3 also includes a second liquid suction needle seat 32, the first liquid suction needle 21 is arranged on the first liquid suction needle seat 22, and the second liquid suction needle seat 32 is arranged on the second liquid suction needle seat 32. The first liquid suction needle seat 22 and the second liquid suction needle seat 32 are provided, so that the first liquid suction needle 21 and the second liquid suction needle 31 can be accurately positioned during assembly, reduce the difficulty of installation, and improve assembly efficiency. When the first liquid suction needle 21 and the second liquid suction needle 31 have malfunctions such as blockage and wear and need to be replaced, the operator can directly disassemble and replace them quickly through the needle seat, without complicated operation procedures, and reduce the equipment downtime maintenance time. The first liquid suction needle seat 22 and the second liquid suction needle seat 32 can buffer vibrations, and avoid the first liquid suction needle 21 and the second liquid suction needle 31 from being collided and shaken by external forces and being bent or damaged.

[0032] Please refer to FIG. 1 , in an optional embodiment, two liquid suction driving members respectively drive the first liquid suction component 2 and the second liquid suction component 3 to suck the liquid of the same stage.

[0033] Please refer to FIG. 2 . In another optional embodiment, a liquid suction driving member provides power to drive the first liquid suction component 2 and the second liquid suction component 3 to respectively suck the liquid of the same level of liquid.

[0034] Please refer to FIG. 1 . In some embodiments, the liquid suction drive assembly 4 includes a first liquid suction drive member 41 and a second liquid suction drive member 42. The first liquid suction drive member 41 is driven and connected to the first liquid suction assembly 2 so that the first liquid suction assembly 2 absorbs the liquid in the container 5 and delivers it to the conduit 1. The second liquid suction drive member 42 is driven and connected to the second liquid suction assembly 3 so that the second liquid suction assembly 3 absorbs the liquid in the container 5 and delivers it to the conduit 1. The first liquid suction drive member 41 and the second liquid suction drive member 42 are controlled separately, so that the first liquid suction assembly 2 and the second liquid suction assembly 3 can prepare for liquid suction at the same time, reducing waiting time. After completing the injection of the previous stage, the two do not need to wait for the same driving source to start in sequence, and can start the liquid suction at the same time, so that the turnover of the liquid suction link is faster, and the subsequent processes are compactly connected, and finally the overall test efficiency of the fully automatic chemiluminescence immunoassay is improved.

[0035] In an optional embodiment, the liquid suction drive assembly 4 may include a peristaltic pump or a metering pump, etc.

[0036] In some embodiments, the first liquid suction drive 41 includes a first peristaltic pump, which is drivably connected to the first liquid suction component 2, and the second liquid suction component includes a second peristaltic pump, which is drivably connected to the second liquid suction component 3. The peristaltic pump relies on a rotary wheel to squeeze the hose to transport the liquid. The suction force generated in this way is relatively gentle, which can reduce the disturbance of key substances such as paramagnetic particles in the container 5. In the immunoassay process, the stability of the state of these particles is crucial to the accuracy of the subsequent luminescent reaction. The gentle liquid suction mode of the dual peristaltic pumps avoids strong suction that causes particle agglomeration and changes in the precipitation state, and maintains the stability of the reaction system.

[0037] The specific structure of the busbar 1 is described below:

[0038] Please refer to FIG3 . In some embodiments, the conduit 1 includes a main channel 11 and a first liquid inlet 12 and a second liquid inlet 13 connected to the main channel. The main channel 11 has a liquid outlet 14 at one end along its length. The first liquid inlet 12 and the second liquid inlet 13 are arranged on both sides of the main channel 11 along its length. The first liquid inlet 12 is connected to the first liquid suction component 2, and the second liquid inlet 13 is connected to the second liquid suction component 3. By setting a single main channel 11 and matching the first liquid inlet 12 and the second liquid inlet 13, the waste liquid from the first liquid suction component 2 and the second liquid suction component 3 can be orderly gathered into the same main channel. Compared with laying complex and dispersed waste liquid output lines for each liquid suction component separately, this simple design greatly simplifies the waste liquid collection process, reduces the number of pipelines, reduces the layout confusion and interference risks caused by multiple pipelines, and improves the stability of the overall system. The concentrated main channel 11 can utilize the natural convergence characteristics of liquid to allow the waste liquid to flow more smoothly to the liquid outlet 14 under the action of gravity or suction. Compared with the multi-branch, decentralized pipeline layout, this structure avoids the problems of uneven diversion of waste liquid between different branches and inconsistent flow resistance, ensuring the rapid and stable discharge of waste liquid, helping to shorten the single liquid aspiration cycle, thereby speeding up the entire cleaning and separation process and improving the test speed of the fully automatic chemiluminescence immunoassay analyzer.

[0039] Please refer to Figure 3. In some embodiments, the first liquid inlet 12 and the second liquid inlet 13 are staggered, which can reduce the pressure shock when the first liquid inlet 12 and the second liquid inlet 13 are simultaneously fed. When the first liquid suction component 2 and the second liquid suction component 3 work at the same time and transport waste liquid to the confluence 1, if the first liquid inlet 12 and the second liquid inlet 13 are arranged opposite each other, the two waste liquid flows will collide head-on, and a large pressure shock will be generated instantly, which may not only interfere with the normal liquid suction of the liquid suction component, but may even cause pipeline vibration and shaking, affecting the stability of the equipment. The staggered setting can make the two waste liquid flows enter the main road 11 in an interlaced manner, avoid direct collision, disperse the concentrated pressure shock, and maintain the stability of the confluence process. The staggered arrangement makes the sequence and flow trajectory of the waste liquid more diverse when it enters the main road 11, so that there is more time and space for the liquids to mix and merge with each other. Compared with the simple counter-mixing under the facing setting, this mixing method is softer and more uniform, which is conducive to the subsequent waste liquid flowing to the liquid outlet 14 in a more stable flow state, reducing the turbulence caused by the local liquid flow rate and uneven concentration, and ensuring the continuity of the entire waste liquid transportation process. Due to the reduction of fluctuations caused by pressure shocks, the first liquid absorption component 2 and the second liquid absorption component 3 are also less disturbed by the reaction force during operation, and can maintain a stable suction force to ensure the accuracy of each liquid absorption amount. This is very critical for the fully automatic chemiluminescence immunoassay instrument. The stable liquid absorption link can lay the foundation for subsequent precise cleaning separation and luminescence reaction, and improve the accuracy of the test results.

[0040] Please refer to FIG3 . In some embodiments, the first liquid inlet 12 includes a plurality of liquid inlets, and the second liquid inlet 13 includes a plurality of liquid inlets. Along the length direction of the main channel 11, all the first liquid inlets 12 and all the second liquid inlets 13 are arranged at intervals, and the first liquid inlet 12 is located between two adjacent second liquid inlets 13. The design of multiple liquid inlets allows the waste liquid from the first liquid suction component 2 and the second liquid suction component 3 to enter the main channel 11 more evenly. Compared with a single liquid inlet, multiple liquid inlets can disperse the inflow of waste liquid, avoid local excessive pressure caused by the concentrated influx of waste liquid from one place, thereby reducing the risks of pipeline blockage, backflow, etc., ensuring that the waste liquid continues to flow to the liquid outlet 14 in a stable manner, and maintaining the smooth operation of the entire liquid suction system.

[0041] 3 , in an optional embodiment, the number of the first liquid inlet 12 and the second liquid inlet 13 may be the same or different. For example, the number of the first liquid inlet 12 and the second liquid inlet 13 may be three, four, five, or the like.

[0042] Please refer to Figure 3. In some embodiments, the diameter of the main road 11 is D, and the diameter of the first liquid inlet 12 or the second liquid inlet 13 is d, satisfying: D≥1.5d. Such a setting can meet the discharge flux requirements of the waste liquid. The larger diameter of the main road 11 provides sufficient space for the waste liquid to flow out. When the first liquid absorption component 2 and the second liquid absorption component 3 transport waste liquid at the same time, the flow of the waste liquid that converges is large, and the relatively wide main road 11 can avoid the congestion of waste liquid. Compared with pipes with too small diameters, this size setting can reduce the resistance to liquid flow, allowing the waste liquid to flow to the liquid outlet 14 without hindrance under natural gravity or moderate suction, maintaining efficient discharge flux, and improving the turnover rate of the overall liquid absorption process. When multiple streams of waste liquid flow into the main road 11 from the liquid inlet, it is easy to cause instantaneous pressure changes. The thicker main road 11 can effectively buffer such pressure fluctuations, avoid reverse impact on the liquid absorption components and pipelines due to sudden pressure increases, and ensure the stability of the liquid absorption process. Since there is enough space to accommodate the waste liquid, even if the liquid inlet speed and flow rate change slightly, it will not cause a sharp rise and fall of the pressure in the main channel 11, and a stable liquid suction power is maintained, which is conducive to accurate liquid suction. At the same time, it can reduce the risk of blockage and extend the service life of the equipment.

[0043] In a second aspect, an embodiment of the present application provides a liquid exchange system, which includes the liquid aspiration device 100 as described in the first aspect.

[0044] In the description of the present application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application.

[0045] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of this application, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0046] In this application, unless otherwise clearly specified and limited, if the terms "installed", "connected", "connected", "fixed" and the like appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances.

[0047] In the present application, unless otherwise clearly specified and limited, if there is a description that a first feature is "above" or "below" a second feature, etc., or similar descriptions appear, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0048] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only implementation method.

[0049] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0050] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be construed as limiting the scope of the patent application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent application shall be subject to the attached claims.

Claims

1. A liquid suction device, characterized in that: include: Busbars; A first liquid suction component, the first liquid suction component is used to suck liquid above a first liquid level in the container, and the first liquid suction component is connected to the manifold; a second liquid-absorbing component, the second liquid-absorbing component being located downstream of the first liquid-absorbing component, the second liquid-absorbing component being used to absorb liquid above a second liquid level in the container, the second liquid level being lower than the first liquid level, the second liquid-absorbing component being in communication with the manifold; and The liquid suction driving component is drivingly connected to the first liquid suction component and the first liquid suction component, so that the first liquid suction component and the second liquid suction component suck the liquid in the container in turn and transport it to the conduit.

2. The liquid suction device according to claim 1, characterized in that The first liquid suction component includes a first liquid suction needle, and the second liquid suction component includes a second liquid suction needle. Along the liquid level height direction of the container, the bottom end of the second liquid suction needle is lower than the first liquid suction needle.

3. The liquid suction device according to claim 2, characterized in that: The first pipetting assembly further includes a first pipetting needle seat, and the second pipetting assembly further includes a second pipetting needle seat. The first pipetting needle is disposed on the first pipetting needle seat, and the second pipetting needle seat is disposed on the second pipetting needle seat.

4. The liquid suction device according to claim 1, characterized in that: The liquid suction drive component includes a first liquid suction drive component and a second liquid suction drive component. The first liquid suction drive component is drivingly connected to the first liquid suction component so that the first liquid suction component sucks the liquid in the container and transports it to the conduit; the second liquid suction drive component is drivingly connected to the second liquid suction component so that the second liquid suction component sucks the liquid in the container and transports it to the conduit.

5. The liquid suction device according to claim 4, characterized in that: The first liquid suction drive component includes a first peristaltic pump, which is drivingly connected to the first liquid suction component, and the second liquid suction component includes a second peristaltic pump, which is drivingly connected to the second liquid suction component.

6. The liquid suction device according to claim 1, characterized in that: The conduit comprises a main channel and a first liquid inlet and a second liquid inlet connected to the main channel. The main channel has a liquid outlet at one end along its length direction. The first liquid inlet and the second liquid inlet are arranged on both sides of the main channel along its length direction. The first liquid inlet is connected to the first liquid absorption component, and the second liquid inlet is connected to the second liquid absorption component.

7. The liquid suction device according to claim 6, characterized in that: The first liquid inlet and the second liquid inlet are staggered.

8. The liquid suction device according to claim 7, characterized in that: The first liquid inlets include a plurality of ports, and the second liquid inlets include a plurality of ports. Along the length direction of the main road, all of the first liquid inlets and all of the second liquid inlets are spaced apart, and the first liquid inlet is located between two adjacent second liquid inlets.

9. The liquid suction device according to claim 6, characterized in that: The diameter of the main channel is D, and the diameter of the first liquid inlet or the second liquid inlet is d, satisfying: D≥1.5d.

10. A liquid replacement system, characterized in that: The liquid exchange system comprises the liquid aspiration device as described in any one of claims 1 to 9.

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