Composite metal oxide and preparation method and application thereof

CN119500125APending Publication Date: 2025-02-25GUANGDONG INST FOR DRUG CONTROL (GUANGDONG INST FOR DRUG QUALITY GUANGDONG PORT DRUG CONTROL INST)
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Patent Information

Application Number
CN202411383656.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-09-30
Publication Date
2025-02-25

AI Technical Summary

Technical Problem

Existing technologies are insufficient to effectively remove parvoviruses from blood products, and traditional methods may affect the medicinal value of raw plasma.

Method used

A composite metal oxide (silver peroxide and manganese dioxide) was prepared by combining ultraviolet light with a silver source, potassium permanganate and a strong reducing agent solution on the surface of a substrate material. This composite metal oxide was then used to inactivate parvovirus.

Benefits of technology

It achieves highly efficient inactivation of parvoviruses, increasing the removal rate by 4-5 logarithmic levels, without affecting the raw plasma components, and is low in cost and easy to operate.

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Abstract

The invention discloses a composite metal oxide. The composite metal oxide is composed of silver peroxide and manganese dioxide. The composite metal oxide disclosed by the invention can be used as a catalyst to realize continuous and efficient inactivation of parvoviruses in blood products in combination with ultraviolet rays, and the catalyst prepared by the invention can be used for improving the parvovirus load removal rate by 4-5 logarithmic levels, that is, the parvoviruses can be completely removed and inactivated when the parvovirus load in raw material plasma does not exceed 10 < 5 > Copies / mL. The method for inactivating the parvovirus by combining the catalyst with ultraviolet rays does not need to adjust pH and add soluble chemical substances, so that the components of raw material plasma are not influenced, the application cost is low, the operation is simple and convenient, and the method has a wide application prospect.
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Citation Information

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